Anne Martin

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• Type de publi. :
• Date de publi. : 23/06/2014
• Auteurs : Thomas LoyauChristelle Hennequet-AntierCécile BerriMarco MoroldoPatrice MartinVincent CousthamMichel Jacques M.J. DuclosSandrine LagarrigueS. YahavAnne Collin
• Organismes : Unité de Recherches Avicoles Unité de Recherches Avicoles Unité de Recherches Avicoles Génétique Animale et Biologie Intégrative Génétique Animale et Biologie Intégrative Unité de Recherches Avicoles Unité de Recherches Avicoles Physiologie, Environnement et Génétique pour l'Animal et les Systèmes d'Elevage [Rennes] Institute of Animal Sciences Unité de Recherches Avicoles

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Résumé : absent

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• Type de publi. : Communication dans un congrès
• Date de publi. : 11/06/2014
• Auteurs : Martin SoubrierMarie-Anne VernyBruno PereiraThomas FrayssacMarion CoudercSandrine Malochet-GuinamandAnne TournadreSylvain MathieuJean-Jacques Dubost
• Organismes : CHU Gabriel Montpied [Clermont-Ferrand] Unité de Nutrition Humaine Unité de biostatistique CHU Gabriel Montpied [Clermont-Ferrand] CHU Gabriel Montpied [Clermont-Ferrand] CHU Gabriel Montpied [Clermont-Ferrand] CHU Gabriel Montpied [Clermont-Ferrand] CHU Gabriel Montpied [Clermont-Ferrand] CHU Gabriel Montpied [Clermont-Ferrand]

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• Type de publi. : Communication dans un congrès
• Date de publi. : 01/06/2014
• Auteurs : Anne FischerBeth ShapiroMartin HellerChristiane SchneePascal Sirand-PugnetJoachim FreyJoerg Jores
• Organismes : International Centre of Insect Physiology and Ecology Pennsylvania State University Friedrich-Loeffler-Institut Friedrich-Loeffler-Institut Biologie du fruit et pathologie Universität Bern / University of Bern International Livestock Research Institute [CGIAR, Nairobi]

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• Type de publi. : Article dans une revue
• Date de publi. : 01/06/2014
• Auteurs : Romain CoustelMathias HaackéV. RouessacJean DurandMartin DrobekA. Julbe
• Organismes : Laboratoire de Chimie Physique et Microbiologie pour l'Environnement Institut Européen des membranes Institut Européen des membranes Institut Européen des membranes Institut Européen des membranes Institut Européen des membranes Institut Européen des membranes
• Publié dans Microporous and Mesoporous Materials le 28/10/2020

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Résumé : In this work the structure-property relationships of SiCxNy(O):H gas separation membranes prepared by PECVD is investigated. X-ray photoemission spectroscopy, fast Fourier transform infra-red spectroscopy and X-ray reflectometry are used to determine both the atomic and chemical bond concentrations in the PECVD membrane materials. Coupling these experimental data with a continuous random network model (cluster approach), a 3D molecular description of the material is proposed. It is shown that such approach can depict the composition and the electronic density of the PECVD Sic(x)N(y)(O):H, thus providing description of material porosity that accounts for the measured gas transport properties of both He and N-2 through the membranes.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/06/2014
• Auteurs : Cong LuJan-Martin HeldtManon Guille-CollignonFrédéric LemaîtreGérard JaouenAnne VessieresChristian Amatore
• Organismes : Processus d'Activation Sélective par Transfert d'Energie Uni-électronique ou Radiatif (UMR 8640) Processus d'Activation Sélective par Transfert d'Energie Uni-électronique ou Radiatif (UMR 8640) Processus d'Activation Sélective par Transfert d'Energie Uni-électronique ou Radiatif (UMR 8640) Laboratoire Charles Friedel Chemical Biology Chimie et biochimie des complexes moléculaires Chemical Biology Processus d'Activation Sélective par Transfert d'Energie Uni-électronique ou Radiatif (UMR 8640)
• Publié dans ChemMedChem le 29/10/2020

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Résumé : no abstract

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• Type de publi. : Article dans une revue
• Date de publi. : 31/05/2014
• Auteurs : Katriina HeikkiläIda E.H. MadsenSolja T. NybergEleonor I. FranssonHugo WesterlundPeter J.M. WesterholmMarianna VirtanenJussi VahteraAri VäänänenTöres TheorellSakari B SuominenMartin J ShipleyPaula SaloReiner RuguliesJaana PenttiJan H. PejtersenTuula OksanenMaria NordinMartin L. NielsenAnne KouvonenAki KoskinenMarkku KoskenvuoAnders KnutssonJane E. FerrieNico DraganoHermann BurrMarianne BorritzJakob B. BjornerLars AlfredssonDavid G BattyArchana Singh-ManouxMika Kivimaki
• Organismes : Finnish Institute of Occupational Health National Research Centre for the Working Environment Finnish Institute of Occupational Health Health Sciences School Institute of Environmental Medicine Department of Epidemiology and Public Health Occupational and Environmental Medicine Finnish Institute of Occupational Health Department of Epidemiology and Public Health Department of Public Health Finnish Institute of Occupational Health Stress Research Institute Department of Public Health Folkhälsan Research Center Department of Epidemiology and Public Health Finnish Institute of Occupational Health Department of Psychology, Turku, Finland Department of Public Health [Copenhagen] National Research Centre for the Working Environment Finnish Institute of Occupational Health The Danish National Centre for Social Research Finnish Institute of Occupational Health Department of Public Health and Clinical Medicine, Occupational and Environmental Medicine Leibniz-Institut für Katalyse School of Sociology, Social Policy, & Social Work Warsaw School of Social Sciences and Humanities Finnish Institute of Occupational Health Department of Public Health Department of Health Sciences Department of Epidemiology and Public Health Institute for Medical Informatics, Biometry, and Epidemiology Federal Institute for Occupational Safety and Health Department of Occupational and Environmental Medicine National Research Centre for the Working Environment Institute of Environmental Medicine Department of Epidemiology and Public Health Department of Epidemiology and Public Health Centre de recherche en épidémiologie et santé des populations Department of Epidemiology and Public Health
• Publié dans Allergy le 26/10/2020

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Résumé : Many patients and healthcare professionals believe that work-related psychosocial stress, such as job strain, can make asthma worse, but this is not corroborated by empirical evidence. We investigated the associations between job strain and the incidence of severe asthma exacerbations in working-age European men and women. We analysed individual-level data, collected between 1985 and 2010, from 102 175 working-age men and women in 11 prospective European studies. Job strain (a combination of high demands and low control at work) was self-reported at baseline. Incident severe asthma exacerbations were ascertained from national hospitalization and death registries. Associations between job strain and asthma exacerbations were modelled using Cox regression and the study-specific findings combined using random-effects meta-analyses. During a median follow-up of 10 years, 1 109 individuals experienced a severe asthma exacerbation (430 with asthma as the primary diagnostic code). In the age- and sex-adjusted analyses, job strain was associated with an increased risk of severe asthma exacerbations defined using the primary diagnostic code (hazard ratio, HR: 1.27, 95% confidence interval, CI: 1.00, 1.61). This association attenuated towards the null after adjustment for potential confounders (HR: 1.22, 95% CI: 0.96, 1.55). No association was observed in the analyses with asthma defined using any diagnostic code (HR: 1.01, 95% CI: 0.86, 1.19). Our findings suggest that job strain is probably not an important risk factor for severe asthma exacerbations leading to hospitalization or death.

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Fichiers liés : Heikkila et al. job strain asthma Allergy 2014.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 31/05/2014
• Auteurs : Guillaume AssiéEric LetouzéMartin FassnachtA. JouinotWindy LuscapOlivia BarreauHanin OmeiriStéphanie RodriguezKarine PerlemoineFernande René-CorailNabila ElarouciSilviu SbieraMatthias KroissBruno AllolioJens WaldmannMarcus QuinklerMassimo MannelliFranco ManteroThomas PapathomasRonald de KrijgerAntoine TabarinVéronique KerlanEric BaudinFrédérique TissierBertrand DoussetLionel GroussinLaurence AmarEric ClauserXavier BertagnaBruno RagazzonFelix BeuschleinRossella LibéAurélien de ReynièsJérôme Bertherat
• Organismes : Institut Cochin Service d'Endocrinologie Génomique Fonctionnelle des Tumeurs Solides Medizinische Klinik und Poliklinik IV Comprehensive Heart Failure Center Endocrine and Diabetes Unit Institut Cochin Service d'Endocrinologie Institut Cochin Institut Cochin Institut Cochin Institut Cochin "Cartes d'Identité des Tumeurs " Medizinische Klinik und Poliklinik IV Endocrine and Diabetes Unit Comprehensive Heart Failure Center Endocrine and Diabetes Unit Erasmus University Medical Center [Rotterdam] Reinier de Graaf Hospital Institut National de la Santé et de la Recherche Médicale Groupe d'Etude de la Thrombose de Bretagne Occidentale Signalisation Hormonale, Physiopathologie Endocrinienne et Métabolique Médecine nucléaire Institut Cochin Hypertension unit Assistance Publique–Hôpitaux de Paris Institut Cochin Pôle Endocrinologie-Diabétologie Adultes-Enfants Medizinische Klinik und Poliklinik IV (le programme) Cartes d'identité des tumeurs Institut Cochin
• Publié dans Nature Genetics le 29/10/2020

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Résumé : Adrenocortical carcinomas (ACCs) are aggressive cancers originating in the cortex of the adrenal gland. Despite overall poor prognosis, ACC outcome is heterogeneous. We performed exome sequencing and SNP array analysis of 45 ACCs and identified recurrent alterations in known driver genes (CTNNB1, TP53, CDKN2A, RB1 and MEN1) and in genes not previously reported in ACC (ZNRF3, DAXX, TERT and MED12), which we validated in an independent cohort of 77 ACCs. ZNRF3, encoding a cell surface E3 ubiquitin ligase, was the most frequently altered gene (21%) and is a potential new tumor suppressor gene related to the β-catenin pathway. Our integrated genomic analyses further identified two distinct molecular subgroups with opposite outcome. The C1A group of ACCs with poor outcome displayed numerous mutations and DNA methylation alterations, whereas the C1B group of ACCs with good prognosis displayed specific deregulation of two microRNA clusters. Thus, aggressive and indolent ACCs correspond to two distinct molecular entities driven by different oncogenic alterations.

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• Type de publi. : Article dans une revue
• Date de publi. : 15/05/2014
• Auteurs : Erik GeisslerAnne-Marie HechtFerenc Horkay
• Organismes : Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères] Laboratoire Interdisciplinaire de Physique [Saint Martin d’Hères] Section on Tissue Biophysics and Biomimetics [Bethesda]
• Publié dans Macromolecular Symposia le 27/10/2020

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Résumé : The effect of the simultaneous presence of mono- and divalent cations on the thermodynamics of polyelectrolyte solutions is not fully understood. In physiological conditions, combinations of these ions affect structure formation in biopolymer systems. It is known that divalent counterions form a tight sheath around the polymer backbone, while monovalent ions are distributed in a diffuse cloud. Dynamic light scattering measurements of the collective diffusion coefficient D and the osmotic compressibility of semi-dilute hyaluronan solutions containing different ratios of sodium and calcium ions are compared with simple polyelectrolyte models. Scaling relationships are derived in terms of polymer concentration and ionic strength J of the added salt. Differences in the effects of sodium and calcium ions are expressed only through J.

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• Type de publi. : Communication dans un congrès
• Date de publi. : 11/05/2014
• Auteurs : Teresa LettieriRaquel N. CarvalhoAugustine ArukweSelim Ait-AissaAnne Bado-NillesStefania BalzamoSabrina BarbizziMonica BuchettiAnders BaunShimshon BelkinMaria BelliMartin BenisekLudek BlahaMirco Dalla BonaFrançois BrionElisa CalabrettaDaniela ContiNicolas CreusotWilfried Sanchez
• Organismes : JRC Institute for Environment and Sustainability JRC Institute for Environment and Sustainability Institut National de l'Environnement Industriel et des Risques Institut National de l'Environnement Industriel et des Risques Stress Environnementaux et BIOsurveillance des milieux aquatiques Istituto Superiore per la Protezione e la Ricerca Ambientale Istituto Superiore per la Protezione e la Ricerca Ambientale Istituto Superiore per la Protezione e la Ricerca Ambientale Istituto Superiore per la Protezione e la Ricerca Ambientale Research Centre for Toxic Compounds in the Environment [Brno] Research Centre for Toxic Compounds in the Environment [Brno] Research Centre for Toxic Compounds in the Environment [Brno] Institut National de l'Environnement Industriel et des Risques Istituto Superiore per la Protezione e la Ricerca Ambientale Istituto Superiore per la Protezione e la Ricerca Ambientale Institut National de l'Environnement Industriel et des Risques Institut National de l'Environnement Industriel et des Risques

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Résumé : Thousands different chemicals are discharged into the environment from agriculture, industry, medical facilities, house-holds. Currently, there is an increasing concern for the environmental impact of mixture of compounds since the additive and eventual synergistic effects are unknown and could produce serious adverse effects. Recently, a document from the European Commission on combination effects of chemicals highlighted the need to ensure that risks associated with chemical mixtures are properly understood and assessed. To address this issue, a joint-effort of 16 European and associated research groups participated to an exercise to test a synthetic reference chemical mixture on the own routine bioassays to investigate the chemical mixtures effects. The reference material included class of pesticides, pharmaceuticals, industrial products, heavy metals and polyaromatic hydrocarbons. The mixures were prepared, each compound at Equivalent Quality Standard (EQS) value, the safety limit concentration allowed by the European Water Framework Directive, (WFD).The bioassays proposed by the groups could cover the entire ecosystem from bacteria to fish as well in vitro assays providing an unique scenario from ecological risk assessment perspective. The results showed that effects were observed at very low concentration on algal-bacteria composition in a marine microcosm, immobilization in crustacean, fish embryo toxicity and frog embryo development. We conclude that some precaution on the chemical mixture assessment should be taken even in case the individual compounds are present at EQS, the safety limit concentration under European legislation.

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Fichiers liés : 2014-151_post-print.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 07/05/2014
• Auteurs : Andrew J ConstableJessica Melbourne-ThomasStuart P CorneyKevin R ArrigoChristophe BarbraudDavid K A BarnesNathaniel L BindoffPhilip W BoydAngelika BrandtDaniel P CostaAndrew T DavidsonHugh W DucklowLouise EmmersonMitsuo FukuchiJulian GuttMark A HindellEileen E HofmannGraham W HosieTakahiro IidaSarah JacobNadine M JohnstonSo KawaguchiNobuo KokubunPhilippe KoubbiMary-Anne LeaAzwianewi MakhadoRob A MassomKlaus MeinersMichael P MeredithEugene J MurphyStephen NicolKeith ReidKate RichersonMartin J RiddleStephen R RintoulWalker O SmithColin SouthwellJonathon S StarkMichael SumnerKerrie M SwadlingKunio T TakahashiPhil N TrathanDirk C WelsfordHenri WeirmerskirchKaren J WestwoodBarbara C WieneckeDieter Wolf-GladrowSimon W WrightJose C XavierPhilippe Ziegler
• Organismes : Centre d'Études Biologiques de Chizé - UMR 7372 Biocenter Grindel and Zoological Museum Australian Antarctic Division National Institute of Polar Research [Tokyo] Alfred-Wegener-Institut, Helmholtz-Zentrum für Polar- und Meeresforschung = Alfred Wegener Institute for Polar and Marine Research = Institut Alfred-Wegener pour la recherche polaire et marine Institute for Marine and Antarctic Studies [Hobart] Australian Antarctic Division Institute for Marine and Antarctic Studies [Hobart] Economics Centre d'Études Biologiques de Chizé - UMR 7372
• Publié dans Global Change Biology le 25/10/2020

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Résumé : Antarctic and Southern Ocean (ASO) marine ecosystems have been changing for at least the last 30 years, including in response to increasing ocean temperatures and changes in the extent and seasonality of sea-ice; the magnitude and direction of these changes differ between regions around Antarctica that could see populations of the same species changing differently in different regions. This paper reviews current and expected changes in ASO physical habitats in response to climate change. It then reviews how these changes may impact the autecology of marine biota of this polar region: microbes, zooplankton, salps, Antarctic krill, fish, cephalopods, marine mammals, seabirds, and benthos. The general prognosis for ASO marine habitats is for an overall warming and freshening, strengthening of westerly winds, with a potential pole-ward movement of those winds and the frontal systems, and an increase in ocean eddy activity. Many habitat parameters will have regionally specific changes, particularly relating to sea-ice characteristics and seasonal dynamics. Lower trophic levels are expected to move south as the ocean conditions in which they are currently found move pole-ward. For Antarctic krill and finfish, the latitudinal breadth of their range will depend on their tolerance of warming oceans and changes to productivity. Ocean acidification is a concern not only for calcifying organisms, but also for crustaceans such as Antarctic krill; it is also likely to be the most important change in benthic habitats over the coming century. For marine mammals and birds, the expected changes primarily relate to their flexibility in moving to alternative locations for food and the energetic cost of longer or more complex foraging trips for those that are bound to breeding colonies. Few species are sufficiently well studied to make comprehensive species-specific vulnerability assessments possible. Priorities for future work are discussed. This article is protected by copyright. All rights reserved.

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