Diego SANCHEZ

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 01/07/2025
• Auteurs : Francesco ColizziPaula Blázquez-SánchezGiovanni BussiIsabelle AndréFederico BallabioThomas BayerFederica BertocchiniErik ButenschönEmanuele CarosatiAlessia de PieroAnia Di Pede-MattatelliLeonardo FaggianLorenzo FavaroPedro Alexandrino FernandesAlfonso FerrettiPeter FojanAndreas GagsteigerEva García-RuizLucia GardossiToni GiorginoNorbert GraefeJonas GunkelDiego JiménezMalene Billeskov KellerGeorg KünzeSierin LimGuy LippensMiguel Maria-SolanoKarolina MitusińskaVicent MolinerGianluca MollaMarthinus Wessel MyburghNicolas PanelCésar Ramírez-SarmientoDominique RocherBirgit StrodelBelén Taroncher RuizOnur TurakCristiano VarroneDaniele VezziniPeter WesthWolfgang Zimmermann
• Organismes : Laboratory of Medicinal Chemistry, Institute for Advanced Chemistry of Catalonia Institute of Marine Sciences / Institut de Ciències del Mar [Barcelona] Leipzig University / Universität Leipzig Scuola Internazionale Superiore di Studi Avanzati / International School for Advanced Studies Toulouse Biotechnology Institute Istituto di Biofisica [Milano] Department of Biotechnology & Enzyme Catalysis, Institute of Biochemistry Leipzig University / Universität Leipzig Dipartimento di Scienze Chimiche e Farmaceutiche Dipartimento di Scienze Chimiche e Farmaceutiche Institute of Marine Sciences / Institut de Ciències del Mar [Barcelona] DAFNAE, University of Padova DAFNAE, University of Padova Department of Microbiology, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa. Universidade do Porto = University of Porto Scuola Normale Superiore di Pisa Istituto Nazionale di Fisica Nucleare [Pisa] Department of Materials and Production [Aalborg] Universität Bayreuth [Deutschland] = University of Bayreuth [Germany] = Université de Bayreuth [Allemagne] Instituto de Catálisis y Petroleoquímica Dipartimento di Scienze Chimiche e Farmaceutiche Istituto di Biofisica [Milano] Leipzig University / Universität Leipzig Leipzig University / Universität Leipzig Division of Biological and Environmental Sciences and Engineering Department of Biotechnology and Biomedicine Leipzig University / Universität Leipzig Center for Scalable Data Analytics and Artificial Intelligence Nanyang Technological University [Singapour] Toulouse Biotechnology Institute Institute of Marine Sciences / Institut de Ciències del Mar [Barcelona] National Research Council of Italy | Consiglio Nazionale delle Ricerche Institute of Advanced Materials “Dipartimento di Biotecnologie e Scienze della Vita” DAFNAE, University of Padova Department of Microbiology, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa. Toulouse Biotechnology Institute Institute for biological and medical engineering [Santiago] DAFNAE, University of Padova Department of Microbiology, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa. Institute of Biological Information Processing [Jülich] Institute of Theoretical and Computational Chemistry Plastics Technology Centre-AIMPLAS Universität Bayreuth [Deutschland] = University of Bayreuth [Germany] = Université de Bayreuth [Allemagne] Department of Chemistry and Bioscience [Aalborg] DAFNAE, University of Padova Department of Microbiology, Stellenbosch University, Private Bag X1, Matieland 7602, South Africa. Department of Biotechnology and Biomedicine Leipzig University / Universität Leipzig

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Résumé : Plastics are essential to modern life, yet poor disposal practices contribute to low recycling rates and environmental accumulation-biological degradation and by-product reuse offer a path to mitigate this global threat. This report highlights key insights, future challenges, and research priorities identified during the CECAM workshop "Computations Meet Experiments to Advance the Enzymatic Depolymerization of Plastics One Atom at a Time", held in Trieste from May 6-8, 2025. The workshop brought together an interdisciplinary community of scientists focused on advancing the sustainable use of plastics through enzyme-based degradation. A key point from the discussions is that many bottlenecks in enzymatic recycling arise not only from process engineering challenges, but also from a limited understanding of the underlying molecular mechanisms. We argue that constraints on economic viability and sustainability (e.g., harsh solvents, high temperatures, substrate crystallinity, pretreatments) can-and should-be addressed directly through enzyme design, provided these factors are understood at the molecular level, in synergy with process optimization. For this, it is essential to rely on the integration of experimental and computational approaches to uncover the molecular and mechanistic basis of enzymatic plastic degradation. We highlight how the small-format structure of the workshop, in line with the usual CECAM format, fostered a collaborative, friendly, and relaxed atmosphere. We hope this report encourages future initiatives and the formation of shared consortia to support an open, collaborative, and bio-based plastic recycling community.

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Fichiers liés : 2507.14413v1.pdf

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Source

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 18/06/2025
• Auteurs : K NaidooJ Ruiz-ZapateroN TessoreB JoachimiA LoureiroN AghanimB AltieriA AmaraL AmendolaS AndreonN AuricchioC BaccigalupiD BagotM BaldiS BardelliP BattagliaA BivianoE BranchiniM BresciaS CameraV CapobiancoC CarboneV.F CardoneJ CarreteroM CastellanoG CastignaniS CavuotiK.C ChambersA CimattiC Colodro-CondeG CongedoL ConversiY CopinF CourbinH.M CourtoisA da SilvaH DegaudenziG de LuciaF DubathX DupacS DusiniStephanie EscoffierM FarinaR FarinelliS FarrensF FaustiniS FerriolF FinelliP FosalbaM FrailisE FranceschiM FumanaS GaleottaK GeorgeB GillisC GiocoliJ Gracia-CarpioA GrazianF GruppW HolmesF HormuthA HornstrupK JahnkeM JhabvalaE KeihänenS KermicheA KiesslingM KilbingerB KubikM KümmelM KunzH Kurki-SuonioA.M.C Le BrunS LigoriP.B LiljeV LindholmI LloroG MainettiD MainoE MaioranoO MansuttiS MarcinO MarggrafM MartinelliN MartinetF MarulliR MasseyE MedinaceliS MeiY MellierM MeneghettiE MerlinG MeylanA MoraL MoscardiniC NeissnerS.-M NiemiC PadillaS PaltaniF PasianK PedersenW.J PercivalV PettorinoS PiresG PolentaM PoncetL.A PopaF RaisonR ReboloA RenziJ RhodesG RiccioE RomelliM RoncarelliC RossetR SagliaZ SakrA.G SánchezD SaponeB SartorisP SchneiderT SchrabbackA SecrounE SefusattiG SeidelM SeiffertS SerranoP SimonC SirignanoG SirriA Spurio ManciniL StancoJ SteinwagnerP Tallada-CrespíD TavagnaccoA.N TaylorI TerenoS ToftR Toledo-MoreoF TorradeflotI TutusausL ValenzianoJ ValiviitaT VassalloG. Verdoes KleijnA VeropalumboY WangJ WellerG ZamoraniF.M ZerbiElena ZuccaV AllevatoM BallardiniM BolzonellaE BozzoC BuriganaR CabanacM CalabreseA CappiD Di FerdinandoJ.A. Escartin VigoL GabarraJ Martín-FleitasS MatthewN MauriR.B MetcalfA PezzottaM PöntinenI RissoV ScottezM SerenoM TentiM VielM WiesmannY AkramiI.T AndikaS AnselmiM ArchidiaconoF Atrio-BarandelaA Balaguera-AntolinezD BertaccaMatthieu BétherminA BlanchardL BlotS BorganiM.L BrownS BrutonA CalabroB Camacho QuevedoF CaroC.S CarvalhoT CastroF CogatoS ConseilA.R CoorayS DaviniG DesprezA Díaz-SánchezJ.J DiazS Di DomizioJ.M DiegoP DimauroA EniaY FangA.G FerrariP.G FerreiraA FinoguenovA FontanaA FrancoK GangaJ García-BellidoT GasparettoV GautardE GaztanagaF GiacominiF GianottiG GozaliaslM GuidiC.M GutierrezA HallC Hernández-MonteagudoH HildebrandtJ HjorthS JoudakiJ.J.E KajavaY KangV KansalD KaragiannisK KiiveriC.C KirkpatrickS KrukM LattanziL LegrandM LemboF LeporiG LeroyG.F LesciJ LesgourguesL LeuzziT.I LiaudatJ Macias-PerezG MaggioM MagliocchettiF MannucciR MaoliC.J.A.P MartinsL MaurinM MiluzioP MonacoC MorettiG MorganteS NadathurA Navarro-AlsinaL PaganoF PassalacquaK PatersonL PatriziiA PisaniD PotterS QuaiM RadovichP.-F RocciS SacquegnaM SahlénD.B SandersE SarpaA SchneiderD SciottiE SellentinL.C SmithK TanidisG TesteraR TeyssierS TosiA TrojaM TucciC ValieriA VenholaD VerganiG VerzaP VielzeufN.A Walton
• Organismes : Institut d'astrophysique spatiale Centre National d'Études Spatiales [Toulouse] Institut de Physique des 2 Infinis de Lyon Institut de Physique des 2 Infinis de Lyon Centre de Physique des Particules de Marseille Astrophysique Interprétation Modélisation Institut de Physique des 2 Infinis de Lyon Centre de Physique des Particules de Marseille Astrophysique Interprétation Modélisation Institut de Physique des 2 Infinis de Lyon Centre de Calcul de l'IN2P3 Laboratoire d'Astrophysique de Marseille AstroParticule et Cosmologie Centre Pierre Binétruy Institut d'Astrophysique de Paris Agence Spatiale Européenne = European Space Agency Agence Spatiale Européenne = European Space Agency Astrophysique Interprétation Modélisation Centre National d'Études Spatiales [Toulouse] AstroParticule et Cosmologie Institut de recherche en astrophysique et planétologie Centre de Physique des Particules de Marseille Institut de recherche en astrophysique et planétologie Institut de recherche en astrophysique et planétologie Joseph Louis LAGRANGE Institut d'Astrophysique de Paris Université de Lille, Sciences et Technologies Laboratoire Univers et Théories Observatoire astronomique de Strasbourg Institut de recherche en astrophysique et planétologie Institut de Physique des 2 Infinis de Lyon AstroParticule et Cosmologie Commissariat à l'énergie atomique et aux énergies alternatives Institut d'Astrophysique de Paris Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Institut d'astrophysique spatiale Centre de Physique des Particules de Marseille Institut d'astrophysique spatiale Centre de Physique des Particules de Marseille

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Résumé : We develop techniques for generating accurate and precise internal covariances for measurements of clustering and weak lensing angular power spectra. These methods are designed to produce non-singular and unbiased covariances for Euclid's large anticipated data vector and will be critical for validation against observational systematic effects. We construct jackknife segments that are equal in area to high precision by adapting the binary space partition algorithm to work on arbitrarily shaped regions on the unit sphere. Jackknife estimates of the covariances are internally derived and require no assumptions about cosmology or galaxy population and bias. Our covariance estimation, called DICES (Debiased Internal Covariance Estimation with Shrinkage), first estimates a noisy covariance through conventional delete-1 jackknife resampling. This is followed by linear shrinkage of the empirical correlation matrix towards the Gaussian prediction, rather than linear shrinkage of the covariance matrix. Shrinkage ensures the covariance is non-singular and therefore invertible, critical for the estimation of likelihoods and validation. We then apply a delete-2 jackknife bias correction to the diagonal components of the jackknife covariance that removes the general tendency for jackknife error estimates to be biased high. We validate internally derived covariances, which use the jackknife resampling technique, on synthetic Euclid-like lognormal catalogues. We demonstrate that DICES produces accurate, non-singular covariance estimates, with the relative error improving by $33\%$ for the covariance and $48\%$ for the correlation structure in comparison to jackknife estimates. These estimates can be used for highly accurate regression and inference.

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Source

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 18/06/2025
• Auteurs : W GillardT MaciaszekE PrietoF GruppA CostilleK JahnkeJ ClemensS DusiniM CarleC SirignanoE MedinaceliS LigoriE FranceschiM TrifoglioW BonR BarbierS FerriolA SecrounN AuricchioP BattagliaC BonoliL CorcioneF HormuthD Le MignantG MorganteC PadillaR Toledo-MoreoL ValenzianoR BenderF.J CastanderP.B LiljeA BalestraJ.-J.C BarriereM BertheC BoderndorfA BonnefoiV CapobiancoR CasasH ChoF DucretJ.-L GimenezW HolmesA HornstrupM JhabvalaE JulloR KohleyB KubikR LaureijsI LloroC MacabiauY MellierG PolentaG.D RaccaA RenziM SchirmerG SeidelM SeiffertG SirriG SmadjaL StancoS WachterH AusselT AuphanB.R GranettR CharyY CopinP HudelotV Le BrunF TorradeflotP.N AppletonP CasenoveP.-Y ChabaudM FrailisM FumanaL GuzzoG MainettiD MainoM MorescoW.J PercivalR ScaramellaM ScodeggioN.R StickleyD VibertY WangJ ZoubianN AghanimB AltieriA AmaraS AndreonC BaccigalupiM BaldiS BardelliA BivianoA BonchiE BranchiniM BresciaJ BrinchmannS CameraG Cañas-HerreraC CarboneJ CarreteroS CasasM CastellanoG CastignaniS CavuotiK.C ChambersA CimattiC Colodro-CondeG CongedoC.J ConseliceL ConversiF CourbinH.M CourtoisJ.-G CubyA da SilvaR da SilvaH DegaudenziG de LuciaA.M Di GiorgioH DoleM DouspisF DubathX DupacStephanie EscoffierM FabriciusM FarinaR FarinelliP FosalbaS FotopoulouN FourmanoitP FranzettiS GaleottaK GeorgeB GillisC GiocoliP Gómez-AlvarezJ Gracia-CarpioA GrazianS.V.H HauganJ HoarH HoekstraI.M HookE KeihänenS KermicheA KiesslingM KümmelM KunzH Kurki-SuonioQ Le Boulc'HA.M.C Le BrunP LiebingV LindholmE MaioranoO MansuttiS MarcinO MarggrafK MarkovicM MartinelliN MartinetF MarulliR MasseyS MaurogordatoH.J MccrackenS MeiM MelchiorM MeneghettiE MerlinG MeylanA MoraL MoscardiniR NakajimaC NeissnerR.C NicholS.-M NiemiJ.W NightingaleS PaltaniF PasianK PedersenV PettorinoS PiresM PoncetL.A PopaL PozzettiF RaisonR ReboloJ RhodesG RiccioE RomelliM RoncarelliE RossettiR SagliaZ SakrA.G SánchezD SaponeB SartorisJ.A SchewtschenkoP SchneiderT SchrabbackE SefusattiP SimonJ SteinwagnerP Tallada-CrespíD TavagnaccoA.N TaylorH.I TeplitzI TerenoS ToftI TutusausJ ValiviitaT VassalloG. Verdoes KleijnA VeropalumboJ WellerA ZaccheiG ZamoraniF.M ZerbiI.A ZinchenkoElena ZuccaV AllevatoM BallardiniM BolzonellaE BozzoC BuriganaR CabanacA CappiD Di FerdinandoJ.A. Escartin VigoL GabarraW.G HartleyJ Martín-FleitasS MatthewN MauriR.B MetcalfA PezzottaM PöntinenC PorcianiI RissoV ScottezM SerenoM TentiM VielM WiesmannY AkramiI.T AndikaS AnselmiM ArchidiaconoF Atrio-BarandelaD BertaccaMatthieu BétherminA BlanchardL BlotS BorganiM.L BrownS BrutonA CalabroB Camacho QuevedoF CaroC.S CarvalhoT CastroY CharlesF CogatoS ConseilA.R CoorayO CucciatiS DaviniF de PaolisG DesprezA Díaz-SánchezJ.J DiazS Di DomizioJ.M DiegoP DimauroPierre-Alain DucA EniaY FangA.M.N FergusonA.G FerrariA FinoguenovA FrancoK GangaJ García-BellidoT GasparettoV GautardE GaztanagaF GiacominiF GianottiG GozaliaslA GregorioM GuidiC.M GutierrezA HallS HemmatiC Hernández-MonteagudoH HildebrandtJ HjorthJ.J.E KajavaY KangV KansalD KaragiannisK KiiveriC.C KirkpatrickS KrukJ Le GraetL LegrandM LemboF LeporiG LeroyG.F LesciJ LesgourguesL LeuzziT.I LiaudatS.J LiuA LoureiroJ Macias-PerezG MaggioM MagliocchettiC ManciniF MannucciR MaoliC.J.A.P MartinsL MaurinC.J.R McpartlandM MiluzioP MonacoA MontoroC MorettiS NadathurK NaidooA Navarro-AlsinaF PassalacquaK PatersonL PatriziiA PisaniD PotterS QuaiM RadovichP.-F RocciS SacquegnaM SahlénD.B SandersE SarpaA SchneiderD SciottiE SellentinL.C SmithK TanidisC TaoG TesteraR TeyssierS TosiA TrojaM TucciC ValieriA VenholaD VerganiG VerzaN.A WaltonL Zalesky
• Organismes : Centre de Physique des Particules de Marseille Centre National d'Études Spatiales [Toulouse] Laboratoire d'Astrophysique de Marseille Laboratoire d'Astrophysique de Marseille Centre de Physique des Particules de Marseille Laboratoire d'Astrophysique de Marseille Laboratoire d'Astrophysique de Marseille Institut de Physique des 2 Infinis de Lyon Institut de Physique des 2 Infinis de Lyon Centre de Physique des Particules de Marseille Laboratoire d'Astrophysique de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Astrophysique Interprétation Modélisation Laboratoire d'Astrophysique de Marseille Laboratoire d'Astrophysique de Marseille Laboratoire d'Astrophysique de Marseille Laboratoire d'Astrophysique de Marseille Institut de Physique des 2 Infinis de Lyon Agence Spatiale Européenne = European Space Agency Institut de Physique des 2 Infinis de Lyon Institut d'Astrophysique de Paris Agence Spatiale Européenne = European Space Agency Institut de Physique des 2 Infinis de Lyon Astrophysique Interprétation Modélisation Centre de Physique des Particules de Marseille Institut de Physique des 2 Infinis de Lyon Institut d'Astrophysique de Paris Laboratoire d'Astrophysique de Marseille Centre National d'Études Spatiales [Toulouse] Laboratoire d'Astrophysique de Marseille Centre de Calcul de l'IN2P3 Laboratoire d'Astrophysique de Marseille Centre de Physique des Particules de Marseille Institut d'astrophysique spatiale Agence Spatiale Européenne = European Space Agency Institut de Physique des 2 Infinis de Lyon Laboratoire d'Astrophysique de Marseille Institut d'astrophysique spatiale Institut d'astrophysique spatiale Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Centre de Calcul de l'IN2P3 Laboratoire d'Astrophysique de Marseille Joseph Louis LAGRANGE Institut d'Astrophysique de Paris AstroParticule et Cosmologie Centre Pierre Binétruy Agence Spatiale Européenne = European Space Agency Agence Spatiale Européenne = European Space Agency Astrophysique Interprétation Modélisation Centre National d'Études Spatiales [Toulouse] Institut de recherche en astrophysique et planétologie Institut de recherche en astrophysique et planétologie Institut de recherche en astrophysique et planétologie Joseph Louis LAGRANGE Institut d'Astrophysique de Paris Université de Lille, Sciences et Technologies Laboratoire Univers et Théories Observatoire astronomique de Strasbourg Institut de recherche en astrophysique et planétologie Laboratoire d'Astrophysique de Marseille Institut de Physique des 2 Infinis de Lyon Observatoire astronomique de Strasbourg AstroParticule et Cosmologie Commissariat à l'énergie atomique et aux énergies alternatives Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Institut d'astrophysique spatiale Centre de Physique des Particules de Marseille Institut d'astrophysique spatiale Centre de Physique des Particules de Marseille

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Résumé : ESA's Euclid cosmology mission relies on the very sensitive and accurately calibrated spectroscopy channel of the Near-Infrared Spectrometer and Photometer (NISP). With three operational grisms in two wavelength intervals, NISP provides diffraction-limited slitless spectroscopy over a field of $0.57$ deg$^2$. A blue grism $\text{BG}_\text{E}$ covers the wavelength range $926$--$1366$ nm at a spectral resolution $R=440$--$900$ for a $0.5''$ diameter source with a dispersion of $1.24$ nm px$^{-1}$. Two red grisms $\text{RG}_\text{E}$ span $1206$ to $1892$ nm at $R=550$--$740$ and a dispersion of $1.37$ nm px$^{-1}$. We describe the construction of the grisms as well as the ground testing of the flight model of the NISP instrument where these properties were established.

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Source

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 11/06/2025
• Auteurs : Georges AadErlend AakvaagBraden Keim AbbottSara AbdelhameedKira AbelingNils Julius AbichtHaider AbidiMohammed AboelelaAsmaa AboulhormaHalina AbramowiczYiming AbulaitiBobby Samir AcharyaAnke AckermannClaire Adam BourdariosLeszek AdamczykSagar AddepalliMatthew John AddisonJahred AdelmanAytul AdiguzelTim AdyeTony AffolderYoav AfikMerve Nazlim AgarasAnamika AggarwalCatalin AgheorghieseiFaig AhmadovSudha AhujaXiaocong AiGiulio AielliArya AikotMalak Ait TamlihatBrahim AitbenchikhMelike AkbiyikTorsten AkessonAndrei AkimovDaiya AkiyamaNilima Nilesh AkolkarSina AktasGian Luigi AlberghiJustin AlbertUna Helena AlbertiPietro AlbicoccoGuillaume AlbouySara AlderweireldtZackary Lee AlegriaMartin AleksaIgor AlexandrovCalin AlexaTheodoros AlexopoulosFabrizio AlfonsiMalte AlgrenMuhammad AlhroobBabar AliHanadi AliShahzad AliSamuel William AlibocusMalik AlievGianluca AlimontiWael AlkakhiCorentin AllaireBenedict AllbrookeJonny AllenJulia Frances AllenPhilip Patrick AllportAlberto AloisioFrancisco AlonsoCristiano AlpigianiZainab Mohammad K AlsolamiAdrian Alvarez FernandezMario Alves CardosoMariagrazia AlviggiMohamed AlyYara Do Amaral CoutinhoAlessandro AmblerChristoph AmelungMaximilian AmerlChristoph AmesThiziri AmezzaDante AmideiBaktash AminiKyle AmirieArtem AmirkhanovSusana Patricia Amor dos SantosKieran Robert AmosDimitra AmperiadouShiwen AnChristos AnastopoulosTim AndeenJohn Kenneth AndersAdam Campbell AndersonAttilio AndreazzaStylianos AngelidakisAaron AngeramiAlexey AnisenkovAlberto AnnoviClaire AntelEgor AntipovMario AntonelliFabio AnulliMasato AokiTakumi AokiMarco AparoLudovica Aperio BellaMariano ApicellaChristian AppeltAram ApyanMichaela ArampatziSergio Javier Arbiol ValChiara ArcangelettiAyana Tamu ArceJean-Francois ArguinSpyros ArgyropoulosJan-Hendrik ArlingOlivier ArnaezHannah ArnoldGiacomo ArtoniHaruka AsadaKanae AsaiSiranush AsatryanNedaa Alexandra AsbahRachel Amy Ashby PickeringAsim Mohammed AslamKetevi Adikle AssamaganRobert AstalosSten AstrandRose AtashiRyan Justin AtkinHicham AtmaniPrachi AtmasiddhaKamil AugstenAdrien AuriolVolker Andreas AustrupGiuseppe AvolioKonstantinos AxiotisAmir AzzamDominik BabalHenri BachacouKonstantinos BachasAlexander BachiuErik BachmannMathias Josef BackesAnthony BadeaTamas Marton BaerPaolo BagnaiaMarzieh BahmaniDaniel BahnerKehang BaiJohn BainesLuke BainesKeith BakerEvelin BakosDebottam Bakshi GuptaLuiz Eduardo Balabram FilhoVeena BalakrishnanRahul BalasubramanianEvgenii BaldinPetr BalekEric BallabeneFabrice BalliLisa Marie BaltesWilliam Keaton BalunasJohannes BalzIsaac BamwidhiElzbieta BanasMarilena BandieramonteAnjishnu BandyopadhyayShubham BansalLiron BarakMarawan BarakatElisabetta BarberioDario BarberisMarlon Benoit BarberoMarten Zefanja BarelTeresa BarillariMartin BarisitsTim BarklowPetr BaronDiego BaronToni BaroncelliAlan BarrJackson BarrFernando BarreiroJoao Barreiro Guimaraes da CostaMaura BarrosSergey BarsovFalk BartelsRainer BartoldusAdam Edward BartonPavol BartosAlexander BasanMarta Baselga BacarditSaleh BashiriAhmed BassalatMatthew Joseph BassoSusan BatajuRussell BateRichard BatesSouad BatlamousMarco BattagliaDaariimaa BattulgaMatteo BauceMichael BauerPatrick BauerLukas BayerTomas BazzanoJames BeachamTristan BeauJean Yves BeaucampPierre-Hugues BeaucheminPhilip BechtleHans Peter BeckKathrin BeckerAndrew BeddallVadim BednyakovChris BeeLars BeemsterMarcia BegalliMichael BegelJanna Katharina BehrJoshua Falco BeirerFlorian BeisiegelMohamed BelfkirGideon BellaLorenzo BellagambaAlain BelleriveCasey Dominik BellgraphPanagiotis BellosKonstantin BeloborodovDriss BenchekrounFatima BendebbaYan BenhammouKees BenkendorferLydia Audrey BeresfordMatteo Mario BerettaElin Bergeaas KuutmannNicolas BergerBenedikt Ludwig BergmannJuerg BeringerGregorio BernardiCatrin BerniusFlorian Urs BernlochnerFlorent BernonAdrian Berrocal GuardiaTracey BerryPeter BertaAnne-Sophie BertholdAnnalisa BertiRaphael BertrandSiegfried BethkeAlessandra BettiAdrian BevanLucas BezioNaman Kumar BhallaShudhashil BharthuarSomadutta BhattaPrajita BhattaraiZubair BhattiKartik Deepak BhideVallary Shashikant BhopatkarRiccardo Maria BianchiGianluca BiancoOtmar BiebelMichela BigliettiSully BillingsleyYassine BimgdiMarcello BindiAnna BinghamAhmet BingulCesare BiniGareth Adam BirdMattias BirmanMarek BirosStanislav BiryukovTobias BisanzEmanuele BisceglieJyoti Prakash BiswalDiptaparna BiswasIngo BlochAndrew James BlueUlla BlumenscheinViktor BobrovnikovLucrezia BoccardoMichael BoehlerBurkhard BohmDanijela BogavacAlexander BogdanchikovLaura BoggiaVeronique BoisvertPetar BokanTomasz BoldMarco BombenMarcella BonaMaarten BoonekampAlbert Gyorgy BorbelyIurii BordulevGuennadi BorissovDaniela BortolettoDavide BoscheriniMartine Fernandez-BosmanKhalil BouaoudaNaseem BouchharLeo BoudetJoseph BoudreauEva Bouhova-ThackerDjamel Eddine BoumedieneRomain BouquetAntonio BoveiaJamie BoydDiallo BoyeIgor BoykoLeon BozianuJuraj BracinikNihal BrahimiGerhard Immanuel BrandtOleg BrandtBenjamin Paul BrauJim BrauRoy Schimmel BrenerLydia BrennerRichard BrennerShikma BresslerGreta BriantiDavid BrittonDaniel BritzgerIan BrockRaymond BrockGustaaf BrooijmansJammel BrooksEthan Michael BrooksLiza BrostLeesa BrownLaura Elaine BruceTim Lukas BrucklerPawel Bruckman de RenstromBen BruersAlessia BruniGraziano BruniDavid BrunnerMarco BruschiNello BruscinoTrygve BuanesQuentin BuatDaniel Alexander BuchinAndy BuckleyOleg BulekovBrendon BullardSergey BurdinCarsten BurgardAngela Maria BurgerBlake Oliver BurghgraveOleksandr BurlayenkoJared Dynes BurlesonJackson Carl BurzynskiElena Laura BuschVolker BuescherPeter John BusseyJohn Mark ButlerCraig Macleod ButtarJonathan ButterworthWill ButtingerCarlos Josue Buxo VazquezAlexey BuzykaevSusana Cabrera UrbanLuca CadamuroHuacheng CaiYuchen CaiYizhou CaiValentina CairoOrhan CakirNoemi CalacePaolo CalafiuraGiovanni CalderiniPhilippe CalfayanLara CalicGiuseppe CalleaLuiz Pereira CalobaDavid CalvetSamuel CalvetReina Coromoto Camacho ToroStefano CamardaDaniel Camarero MunozPaolo CamarriClement CamincherMario CampanelliAlessandra CamplaniVincenzo CanaleAli Can CanbayEnzo CanoneroJosu Cantero GarciaYumeng CaoFrancesca CapocasaMarcella CapuaAntonio CarboneRoberto CardarelliJuan Carlos CardenasMichael Patrick CardiffGiovandomenico CarducciTancredi CarliGiampaolo CarlinoJuan Ignacio CarlottoBen CarlsonEvan Michael CarlsonJoseph CarmignaniLeonardo CarminatiAlberto CarnelliMaria CarnesaleSascha CaronEdson Carquin LopezIsabel Beth CarrSonia CarraGiuseppe CarrattaClara Carrion MartinezAnthony Maurel CarrollPilar Casado LechugaPierluigi CasolaroMaximilian CasparFlorencia Luciana CastilloLucia Castillo GarciaVictoria Castillo GimenezNuno CastroAndrea CatinaccioJames CatmoreTom CavaliereViviana CavaliereLaura Juliana Caviedes BetancourtEmre CelebiSofia CellaVilius CepaitisKarel CernyAugusto Santiago CerqueiraAlex CerriLucio CerritoFabio CeruttiBeatrice CervatoAlberto CervelliGianmario CesariniSerkant CetinPaul Mickael ChabrillatRagansu ChakkappaiSnigdho 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• Organismes : Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules AstroParticule et Cosmologie Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies AstroParticule et Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire des deux Infinis de Toulouse Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules AstroParticule et Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie AstroParticule et Cosmologie Laboratoire des deux Infinis de Toulouse AstroParticule et Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille AstroParticule et Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire des deux Infinis de Toulouse Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire des deux Infinis de Toulouse Laboratoire des deux Infinis de Toulouse Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire des deux Infinis de Toulouse Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire des deux Infinis de Toulouse Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire des deux Infinis de Toulouse Laboratoire de Physique des 2 Infinis Irène Joliot-Curie

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Résumé : This paper presents the first observation of top-quark pair production in association with two photons ($t\bar{t}\gamma\gamma$). The measurement is performed in the single-lepton decay channel using proton-proton collision data collected by the ATLAS detector at the Large Hadron Collider. The data correspond to an integrated luminosity of 140 fb$^{-1}$ recorded during Run 2 at a centre-of-mass energy of 13 TeV. The $t\bar{t}\gamma\gamma$ production cross section, measured in a fiducial phase space based on particle-level kinematic criteria for the lepton, photons, and jets, is found to be $2.42^{+0.58}_{-0.53}\, \text{fb}$, corresponding to an observed significance of 5.2 standard deviations. Additionally, the ratio of the production cross section of $t\bar{t}\gamma\gamma$ to top-quark pair production in association with one photon is determined, yielding $(3.30^{+0.70}_{-0.65})\times 10^{-3}$.

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