Diego SANCHEZ

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• Type de publi. : Article dans une revue
• Date de publi. : 01/11/2016
• Auteurs : Andrea Gloria-SoriaDiego AyalaAmbicadutt BheecarryOlger Calderon-ArguedasDave ChadeeMarina ChiapperoMaureen CoetzeeKhouaildi Bin ElaheeIldefonso Fernandez-SalasHany KamalBasile KamgangEmad KhaterLaura D KramerVicki KramerAlma Lopez-SolisJoel LutomiahAdemir J MartinsMaria Victoria MicieliChristophe PaupyAlongkot PonlawatNil RaholaSyed Basit RasheedJoshua RichardsonAmag SalehRosa Maria Sanchez-CasasGonçalo SeixasCarla SousaWalter TabachnickAdriana TroyoJeffrey R Powell
• Organismes : Yale University [New Haven] Diversity, ecology, evolution & Adaptation of arthropod vectors Ministry of Health and Quality of Life Centro de Investigación en Enfermedades Tropicales The University of the West Indies [Kingston] Universidad Nacional de Córdoba [Argentina] University of the Witwatersrand [Johannesburg] Ministry of Health and Quality of Life Centro Regional de Investigación en Salud Pública = Regional Centre of Research in Public Health [Tapachula, Mexique] Centre for Research in Infectious Diseases [Yaoundé] King Saud University [Riyadh] Wadsworth Center Centro Regional de Investigación en Salud Pública = Regional Centre of Research in Public Health [Tapachula, Mexique] Kenya Medical Research Institute Fundação Oswaldo Cruz / Oswaldo Cruz Foundation Centro de Estudios Parasitologicos y de Vectores [La Plata] Diversity, ecology, evolution & Adaptation of arthropod vectors Armed Forces Research Institute of Medical Sciences [Bangkok] Diversity, ecology, evolution & Adaptation of arthropod vectors University of Peshawar Yale University [New Haven] King Saud University [Riyadh] Universidade Nova de Lisboa = NOVA University Lisbon Universidade Nova de Lisboa = NOVA University Lisbon University of Florida [Gainesville] Universidad de Costa Rica Yale University [New Haven]
• Publié dans Molecular Ecology le 29/10/2020

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Résumé : Mosquitoes, especially Aedes aegypti, are becoming important models for studying invasion biology. We characterized genetic variation at 12 microsatellite loci in 79 populations of Ae. aegypti from 30 countries in six continents, and used them to infer historical and modern patterns of invasion. Our results support the two subspecies Ae. aegypti formosus and Ae. aegypti aegypti as genetically distinct units. Ae. aegypti aegypti populations outside Africa are derived from ancestral African populations and are monophyletic. The two subspecies co-occur in both East Africa (Kenya) and West Africa (Senegal). In rural/forest settings (Rabai District of Kenya), the two subspecies remain genetically distinct, whereas in urban settings, they introgress freely. Populations outside Africa are highly genetically structured likely due to a combination of recent founder effects, discrete discontinuous habitats and low migration rates. Ancestral populations in sub-Saharan Africa are less genetically structured, as are the populations in Asia. Introduction of Ae. aegypti to the New World coinciding with trans-Atlantic shipping in the 16th to 18th centuries was followed by its introduction to Asia in the late 19th century from the New World or from now extinct populations in the Mediterranean Basin. Aedes mascarensis is a genetically distinct sister species to Ae. aegypti s.l. This study provides a reference database of genetic diversity that can be used to determine the likely origin of new introductions that occur regularly for this invasive species. The genetic uniqueness of many populations and regions has important implications for attempts to control Ae. aegypti, especially for the methods using genetic modification of populations.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/10/2016
• Auteurs : Brian FinanChristoffer ClemmensenZhimeng ZhuKerstin StemmerKarine GauthierLuisa MüllerMeri de AngelisKristin MorethFrauke NeffDiego Perez-TilveKatrin FischerDominik LutterMiguel Sánchez-GarridoPeng LiuJan TuckermannMohsen MalehmirMarc HealyAchim WeberMathias HeikenwalderMartin JastrochMaximilian KleinertSigrid JallSara BrandtFrederic FlamantKarl-Werner SchrammHeike BiebermannYvonne DöringChristian WeberKirk HabeggerMichaela KeuperVasily GelfanovFa LiuJosef KöhrleJan RozmanHelmut FuchsValerie Gailus-DurnerMartin Hrabě de AngelisSusanna HofmannBin YangMatthias TschöpRichard DimarchiTimo Müller
• Organismes : Institut de Génomique Fonctionnelle de Lyon
• Publié dans Cell le 28/10/2020

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Résumé : Glucagon and thyroid hormone (T3) exhibit therapeutic potential for metabolic disease but also exhibit undesired effects. We achieved synergistic effects of these two hormones and mitigation of their adverse effects by engineering chemical conjugates enabling delivery of both activities within one precisely targeted molecule. Coordinated glucagon and T3 actions synergize to correct hyperlipidemia, steatohepatitis, atherosclerosis, glucose intolerance, and obesity in metabolically compromised mice. We demonstrate that each hormonal constituent mutually enriches cellular processes in hepatocytes and adipocytes via enhanced hepatic cholesterol metabolism and white fat browning. Synchronized signaling driven by glucagon and T3 reciprocally minimizes the inherent harmful effects of each hormone. Liver-directed T3 action offsets the diabetogenic liability of glucagon, and glucagon-mediated delivery spares the cardiovascular system from adverse T3 action. Our findings support the therapeutic utility of integrating these hormones into a single molecular entity that offers unique potential for treatment of obesity, type 2 diabetes, and cardiovascular disease.

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• Type de publi. : Article dans une revue
• Date de publi. : 29/08/2016
• Auteurs : Alexander AabPedro AbreuMarco AgliettaImen Al SamaraiIvone AlbuquerqueIngomar AllekotteAlejandro AlmelaJesus Alvarez CastilloJaime Alvarez-MuñizMichelangelo AmbrosioGioacchino Alex AnastasiLuis AnchordoquiBelén AndradaSofia AndringaCarla AramoFernando ArquerosNicusor ArseneHernán Gonzalo AsoreyPedro AssisJulien AublinGualberto AvilaAlina Mihaela BadescuAlexandru BalaceanuRicardo Jorge Barreira LuzColin BausJim BeattyKarl-Heinz BeckerJose A BellidoC. BeratMario Edoardo BertainaXavier BertouPeter BiermannPierre BilloirJonathan BiteauSimon G BlaessAlberto BlancoJiri BlazekCarla BleveMartina BoháčováDenise BoncioliCarla BonifaziNataliia BorodaiAna Martina BottiJeffrey BrackIliana BrancusThomas BretzAriel BridgemanFlorian Lukas BriechlePeter BuchholzAntonio BuenoStijn BuitinkMario BuscemiKaren S Caballero-MoraLorenzo CaccianigaÁngel CancioFabrizia CanforaLaurentiu CarameteRossella CarusoAntonella CastellinaGabriella CataldiLorenzo CazonRosanna CesterAlan G ChavezJose Augusto ChinellatoJiri ChudobaRoger W ClayRoberta ColalilloAlan ColemanLaura CollicaMaria Rita ColucciaRuben ConceiçãoFernando ContrerasMathew J CooperStephane CoutuCorbin CovaultJames CroninStefano d'AmicoBruno DanielSergio DassoKai DaumillerBruce R DawsonRogerio M de AlmeidaSijbrand J de JongGiuseppe de MauroJoao de Mello NetoIvan de MitriJaime de OliveiraVitor de SouzaJoachim DebatinOlivier DelignyClaudio Di GiulioArmando Di MatteoMary Lucia Díaz CastroFrancisco DiogoCarola DobrigkeitJuan Carlos d'OlivoAlexei DorofeevRita dos AnjosMaria Teresa DovaAndrej DundovicJan EbrRalph EngelMartin ErdmannMona ErfaniCarlos O EscobarJoão EspadanalAlberto EtchegoyenHeino FalckeKe FangGlennys FarrarAnderson FauthNorberto FazziniBrian FickJuan Manuel FigueiraAndrej FilipčičOctavian FratuMartín Miguel FreireToshihiro FujiiAlan FusterRomain GaiorBeatriz GarcíaDiego Garcia-PintoFlorian GatéHartmut GemmekeAlexandru Gherghel-LascuPiera Luisa GhiaUgo GiaccariMarco GiammarchiMaria GillerDariusz GłasChristian GlaserHenry GlassGeraldina GolupMariano Gómez BerissoPrimo F Gómez VitaleNicolás GonzálezBen GookinAlessio GorgiPeter GorhamPhilippe GouffonAurelio GrilloTrent D GrubbFausto GuarinoGermano GuedesMatías Rolf HampelPatricia HansenDiego HarariThomas A HarrisonJohn HartonQader Dorosti HasankiadehAndreas HaungsThomas HebbekerDieter HeckPhilipp HeimannAlexander E HerveGary C HillCarlos HojvatEwa HoltPiotr HomolaJörg HörandelPavel HorvathMiroslav HrabovskýTim HuegeJohannes HulsmanAntonio InsoliaPaula Gina IsarIngolf JandtStefan JansenJeffrey A JohnsenMariela JosebachuiliAlex KääpäOlga KambeitzKarl-Heinz KampertPeter KasperIgor KatkovBianca KeilhauerErnesto KempJulian KempRoger KieckhaferHans KlagesMatthias KleifgesJonny KleinfellerRaphael KrauseNicole KrohmDaniel KuempelGasper Kukec MezekNorbert KunkaAlaa Kuotb AwadDanielle LahurdMarkus LauscherPaul LebrunRemigiusz LeguminaMarcelo Augusto Leigui de OliveiraA. Letessier SelvonIsabelle Lhenry-YvonKatrin LinkLuis LopesRebeca LópezAida López CasadoQuentin LuceAgustin LuceroMax MalacariManuela MallamaciDusan MandatPaul MantschAnalisa MariazziIoana MarişGiovanni MarsellaDaniele MartelloHumberto MartinezOscar Martínez BravoJimmy Masías MezaHermann-Josef MathesSebastian MathysJames MatthewsJohn MatthewsGiorgio MatthiaeEric MayottePeter MazurCarlos MedinaGustavo Medina-TancoDiego MeloAlexander MenshikovStefano MessinaMaria Isabel MichelettiLukas MiddendorfIgnacio A MinayaLino MiramontiBogdan MitricaDaniela MocklerLaura Molina-BuenoSilvia MollerachF. MontanetCarlo MorelloMiguel MostafáGero MüllerMarcio Aparecido MullerSarah MüllerIvo NaranjoLukas NellenJens NeuserPhong H NguyenMihai Niculescu-OglinzanuMarcus NiechciolLukas NiemietzTim NiggemannDave NitzDalibor NosekVladimir NovotnyLyberis NožkaLuis NúñezLivingstone OchiloFoteini OikonomouAngela OlintoDaniel Pakk Selmi-DeiMiroslav PalatkaJuan PallottaPhilipp PapenbreerGonzalo ParenteAlejandra ParraThomas PaulMiroslav PechFrancisco PedreiraJan PękalaRodrigo PelayoJesús Peña-RodriguezLuiz Augusto PereiraLorenzo PerroneChristine PetersSergio PetreraJamyang PhuntsokRicardo PiegaiaTanguy PierogPablo PieroniMário PimentaValerio PirronelloManuel PlatinoMatthias PlumCzeslaw PorowskiRaul Ribeiro PradoPaolo PriviteraMichael ProuzaEduardo J QuelSven QuerchfeldSean QuinnRaúl Ramos-PollanJulian RautenbergDiego RavignaniDarius ReinertBenoît RevenuJan RidkyMarkus RissePablo RistoriVincenzo RiziWashington Rodrigues de CarvalhoGonzalo Rodriguez FernandezJorge Rubén Rodriguez RojoDmytro RogozinMarkus RothEsteban RouletAdrian RoveroSteven J SaffiAlexandra SaftoiuHumberto SalazarAhmed SalehFrancisco Salesa GreusGaetano SalinaJose Sanabria GomezFederico SánchezPatricia Sanchez-LucasEdivaldo Moura SantosEva SantosFred SarazinBiswaijt SarkarRaul SarmentoChristian A SarmientoRicardo SatoMarkus SchauerViviana ScheriniHarald SchielerMichael SchimpDavid SchmidtOlaf ScholtenPetr SchovánekFrank G SchröderAlexander SchulzJohannes SchulzJohannes SchumacherSergio SciuttoAlberto SegretoMariangela SettimoAmir ShadkamRonald C ShellardGuenter SiglGaia SilliOctavian SimaAndrzej ŚmiałkowskiRadomir ŠmídaGregory SnowPaul SommersSebastian SonntagJennifer SorokinRuben SquartiniDenis StancaSamo StaničJaroslaw StasielakP. StassiFrancesco StrafellaFederico SuarezMauricio Suarez DuránTristan SudholzTiina SuomijärviA. Daniel SupanitskyJohn SwainZbigniew SzadkowskiAlvaro TaboadaOscar Alejandro TabordaAlex TapiaVanessa Menezes TheodoroCharles TimmermansCarlos J Todero PeixotoLenka TomankovaBernardo ToméGuillermo Torralba ElipeDiego Torres MachadoMarco TorriPetr TravnicekMarta TriniRalf UlrichMichael UngerMartin UrbanJose F Valdés GaliciaInes ValiñoLaura ValoreGuus van AarPatrick van BodegomA. M. van den BergArjen van VlietEnrique VarelaBernardo Vargas CárdenasGary VarnerJose R VázquezRicardo VázquezDarko VeberičIndira D Vergara QuispeValerio VerziJakub VichaLuis VillaseñorSerguei VorobiovHernan WahlbergOscar WainbergDavid WalzAlan WatsonMarc WeberAndreas WeindlLawrence WienckeHenryk WilczyńskiTobias WinchenDavid WittkowskiBrian WundheilerSarka WykesLili YangDiana YelosAlexey YushkovEnrique ZasDanilo ZavrtanikMarko ZavrtanikArnulfo ZepedaBenedikt ZimmermannMichael ZiolkowskiZizhao ZongFrancesca Zuccarello
• Organismes : Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie
• Publié dans Physical Review D le 02/11/2020

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Résumé : On September 14, 2015 the Advanced LIGO detectors observed their first gravitational-wave (GW) transient GW150914. This was followed by a second GW event observed on December 26, 2015. Both events were inferred to have arisen from the merger of black holes in binary systems. Such a system may emit neutrinos if there are magnetic fields and disk debris remaining from the formation of the two black holes. With the surface detector array of the Pierre Auger Observatory we can search for neutrinos with energy above 100 PeV from point-like sources across the sky with equatorial declination from about -65 deg. to +60 deg., and in particular from a fraction of the 90% confidence-level (CL) inferred positions in the sky of GW150914 and GW151226. A targeted search for highly-inclined extensive air showers, produced either by interactions of downward-going neutrinos of all flavors in the atmosphere or by the decays of tau leptons originating from tau-neutrino interactions in the Earth's crust (Earth-skimming neutrinos), yielded no candidates in the Auger data collected within $\pm 500$ s around or 1 day after the coordinated universal time (UTC) of GW150914 and GW151226, as well as in the same search periods relative to the UTC time of the GW candidate event LVT151012. From the non-observation we constrain the amount of energy radiated in ultrahigh-energy neutrinos from such remarkable events.

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• Type de publi. : Article dans une revue
• Date de publi. : 26/07/2016
• Auteurs : Bentham JamesCesare Mariachiara DiStevens Gretchen AZhou BinBixby HonorCowan MelanieFortunato LéaHajifathalian KavehLu YuanRiley Leanne MKontis VasilisPaciorek Christopher JEzzati MajidAbdeen Ziad AHamid Zargar AbdulAbu-Rmeileh Niveen MAcosta-Cazares BenjaminAdams RobertAekplakorn WichaiAguilar-Salinas Carlos AAgyemang CharlesAhmadvand AlirezaAhrens WolfgangAl-Hazzaa Hazzaa MAl-Othman Amani RashedRaddadi Rajaa AlAli Mohamed MAlkerwi Ala'AAlvarez-Pedrerol MarAly EmanAmouyel PhilippeAmuzu AntoinetteAndersen Lars BoAnderssen Sigmund AAnjana Ranjit MohanAounallah-Skhiri HajerAriansen IngerAris TahirArlappa NimmathotaArveiler DominiqueAssah Felix KAvdicová MáriaAzizi FereidounBabu Bontha VBahijri SuhadBalakrishna NagallaBandosz PiotrBanegas José RBarbagallo Carlo MBarceló AlbertoBarkat AminaBarros Mauro VBata IqbalBatieha Anwar MBatista Rosangela LBaur Louise ABeaglehole RobertRomdhane Habiba BenBenet MikhailBennett James EBernabe-Ortiz AntonioBernotiene GailuteBettiol HeloisaBhagyalaxmi AroorBharadwaj SumitBhargava Santosh KBhatti ZaidBhutta Zulfiqar ABi HongshengBi YufangBjerregaard PeterBjertness EspenBjertness Marius BBjörkelund CeciliaBlokstra AnnekeBo SimonaBobak MartinBoddy Lynne MBoehm Bernhard OBoeing HeinerBoissonnet Carlos PBongard VaninaBovet PascalBraeckman LutgartBragt Marjolijn CeBrajkovich ImperiaBranca FrancescoBreckenkamp JuergenBrenner HermannBrewster Lizzy MBrian Garry RBruno GraziellaBueno-De-Mesquita Hb(as)Bugge AnnaBurns ConLeón Antonio Cabrera DeCacciottolo JosephCama TilemaCameron ChristineCamolas JoséCan GünayCândido Ana Paula CCapuano VincenzoCardoso Viviane CCarlsson Axel CCarvalho Maria JCasanueva Felipe FCasas Juan-PabloCaserta Carmelo AChamukuttan SnehalathaChan Angelique WChan QueenieChaturvedi Himanshu KChaturvedi NishiChen Chien-JenChen FangfangChen HuashuaiChen ShuohuaChen ZhengmingCheng Ching-YuChetrit AngelaChiolero ArnaudChiou Shu-TiChirita-Emandi AdelaCho BelongCho YumiChristensen KaareChudek JerzyCifkova RenataClaessens FrankClays ElsConcin HansCooper CyrusCooper RachelCoppinger Tara CCostanzo SimonaCottel DominiqueCowell ChrisCraig Cora LCrujeiras Ana Bd'Arrigo Graziellad'Orsi EleonoraDallongeville JeanDamasceno AlbertinoDamsgaard Camilla TDanaei GoodarzDankner RachelDauchet LucBacker Guy DeBacquer Dirk DeGaetano Giovanni DeHenauw Stefaan DeSmedt Delphine DeDeepa MohanDeev Alexander DDehghan AbbasDelisle HéléneDelpeuch FrancisDeschamps ValérieDhana KlodianCastelnuovo Augusto F DiDias-Da-Costa Juvenal SoaresDiaz AlejandroDjalalinia ShirinDo Ha TpDobson Annette JDonfrancesco ChiaraDonoso Silvana PDöring AngelaDoua KouamelanDrygas WojciechDzerve VilnisEgbagbe EEggertsen RobertEkelund UlfAti Jalila ElElliott PaulEngle-Stone ReinaErasmus Rajiv TErem CihangirEriksen LouisePeña Jorge Escobedo-de LaEvans AlunFaeh DavidFall Caroline HFarzadfar FarshadFelix-Redondo Francisco JFerguson Trevor SFernández-Bergés DanielFerrante DanielFerrari MarikaFerreccio CatterinaFerrieres JeanFinn Joseph DFischer KristaFlores Eric MonterubioFöger BernhardFoo Leng HuatForslund Ann-SofieForsner MariaFortmann Stephen PFouad Heba MFrancis Damian KFranco Maria Do CarmoFranco Oscar HFrontera GuillermoFuchs Flavio DFuchs Sandra CFujita YukiFurusawa TakuroGaciong ZbigniewGafencu MihaiGareta DickmanGarnett Sarah PGaspoz Jean-MichelGasull MagdaGates LouiseGeleijnse Johanna MGhasemian AnooshehGiampaoli SimonaGianfagna FrancescoGiovannelli JonathanGiwercman AleksanderGoldsmith Rebecca AGonçalves HelenGross Marcela GonzalezRivas Juan P GonzálezGorbea Mariano BonetGottrand FredericGraff-Iversen SidselGrafnetter DušanGrajda AnetaGrammatikopoulou Maria GGregor Ronald DGrodzicki TomaszGrøntved AndersGruden GrabriellaGrujic VeraGu DongfengGualdi-Russo EmanuelaGuan Ong PengGudnason VilmundurGuerrero RamiroGuessous IdrisGuimaraes Andre LGulliford Martin CGunnlaugsdottir JohannaGunter MarcGuo XiuhuaGuo YinGupta Prakash CGureje OyeGurzkowska BeataGutierrez LauraGutzwiller FelixHalkjær JytteHambleton Ian RHardy RebeccaKumar Rachakulla HariHata JunHayes Alison JHe JiangHendriks Marleen ElisabethCadena Leticia HernandezHerrala SauliHeshmat RaminHihtaniemi Ilpo TapaniHo Sai YinHo Suzanne CHobbs MichaelHofman AlbertHormiga Claudia MHorta Bernardo LHouti LeilaHowitt ChristinaHtay Thein TheinHtet Aung SoeHtike Maung Maung ThanHu YonghuaHusseini AbdullatifHuu Chinh NguyenHuybrechts IngeHwalla NahlaIacoviello LiciaIannone Anna GIbrahim Mohsen MIkeda NayuIkram M ArfanIrazola Vilma EIslam MuhammadIvkovic VanjaIwasaki MasanoriJackson Rod TJacobs Jeremy MJafar TazeenJamil Kazi MJamrozik KonradJanszky ImreJasienska GrazynaJelakovic BojanJiang Chao QiangJoffres MichelJohansson MattiasJonas Jost BJørgensen TorbenJoshi PradeepJuolevi AnneJurak GregorJureša VesnaKaaks RudolfKafatos AnthonyKalter-Leibovici OfraKapantais EfthymiosKasaeian AmirKatz JoanneKaur PrabhdeepKavousi MaryamKeil UlrichBoker Lital KeinanKeinänen-Kiukaanniemi SirkkaKelishadi RoyaKemper Han CgKengne Andre PKersting MathildeKey TimothyKhader Yousef SalehKhalili DavoodKhang Young-HoKhaw Kay-Tee HKhouw Ilse MslKiechl StefanKillewo JaphetKim JeongseonKlimont JeannetteKlumbiene JurateKoirala BhaweshKolle ElinKolsteren PatrickKorrovits PaulKoskinen SeppoKouda KatsuyasuKoziel SlawomirKratzer WolfgangKrokstad SteinarKromhout DaanKruger Herculina SKubinova RuzenaKujala Urho MKula KrzysztofKulaga ZbigniewKumar R KrishnaKurjata PawelKusuma Yadlapalli SKuulasmaa KariKyobutungi CatherineLaamiri Fatima ZahraLaatikainen TiinaLachat CarlLaid YoucefLam Tai HingLandrove OrlandoLanska VeraLappas GeorgLarijani BagherLaugsand Lars ELaxmaiah AvulaBao Khanh Le NguyenLe Tuyen DLeclercq CatherineLee JeannetteLee JeongheeLehtimäki TerhoLekhraj RampalLeón-Muñoz Luz MLi YanpingLilly Christa LLim Wei-YenLima-Costa M FernandaLin Hsien-HoLin XuLinneberg AllanLissner LaurenLitwin MieczyslawLiu JingLorbeer RobertoLotufo Paulo ALozano José EugenioLuksiene DaliaLundqvist AnnamariLunet NunoLytsy PerMa GuanshengMa JunMachado-Coelho George LlMachi SukaMaggi StefaniaAno Dianna JMaire BernardMakdisse MarciaMalekzadeh RezaMalhotra RahulRao Kodavanti MallikharjunaMalyutina SofiaManios YannisMann Jim IManzato EnzoMargozzini PaulaMarkey OonaghMarques-Vidal PedroMarrugat JaumeYves Martin-PrevelMartorell ReynaldoMasoodi Shariq RMathiesen Ellisiv BMatsha Tandi EMazur ArturMbanya Jean Claude NMcfarlane Shelly RMcgarvey Stephen TMckee MartinMclachlan StelaMclean Rachael MMcnulty Breige AYusof Safiah MdMediene-Benchekor SounniaMeirhaeghe AlineMeisinger ChristaMenezes Ana Maria BMensink Gert BmMeshram Indrapal IMetspalu AndresMi JieMichaelsen Kim FMikkel KairitMiller Jody CMiquel Juan FranciscoMiranda J JaimeMišigoj-Durakovic MarjetaMohamed Mostafa KMohammad KazemMohammadifard NoushinMohan ViswanathanYusoff Muhammad Fadhli MohdMolbo DrudeMøller Niels CMolnár DénesMondo Charles KMonterrubio Eric AMonyeki Kotsedi Daniel KMoreira Leila BMorejon AlainMoreno Luis AMorgan KarenMortensen Erik LykkeMoschonis GeorgeMossakowska MalgorzataMostafa AyaMota JorgeMotlagh Mohammad EsmaeelMotta JorgeMu Thet ThetMuiesan Maria LorenzaMüller-Nurasyid MartinaMurphy NeilMursu JaakkoMurtagh Elaine MMusa Kamarul ImranMusil VeraNagel GabrieleNakamura HarunobuJana NámešnáNang Ei Ei KNangia Vinay BNankap MartinNarake SameerMuñoz Eva Maria NavarreteNeal William ANenko IlonaNeovius MartinNervi FlavioNeuhauser Hannelore KNguyen Nguyen DNguyen Quang NgocMartínez Ramfis E NietoNing GuangNinomiya ToshiharuNishtar SaniaNoale MariannaNorat TeresaNoto DavideNsour Mohannad AlO'Reilly DermotOh KyungwonOlayan Iman HOlinto Maria Teresa AnselmoOltarzewski MaciejOmar Mohd AOnat AltanOrdunez PedroOrtiz Ana POsler MereteOsmond CliveOstojic Sergej MOtero Johanna AOvervad KimOwusu-Dabo EllisPaccaud Fred MichelPadez CristinaPahomova ElenaPajak AndrzejPalli DomenicoPalloni AlbertoPalmieri LuigiPanda-Jonas SonghomitraPanza FrancescoParnell Winsome RParsaeian MahboubehPecin IvanPednekar Mangesh SPeeters Petra HPeixoto Sergio VianaPeltonen MarkkuPereira Alexandre CPérez Cynthia MPeters AnnettePetkeviciene JaninaPeykari NiloofarPham Son ThaiPigeot IrisPikhart HynekPilav AidaPilotto LorenzaPistelli FrancescoPitakaka FredaPiwonska AleksandraPlans-Rubió PedroPoh Bee KoonPorta MiquelPortegies Marileen LpPoulimeneas DimitriosPradeepa RajendraPrashant MathurPrice Jacqueline FPuiu MariaTartu Margus PunabQasrawi Radwan FQorbani MostafaBao Tran QuocRadisauskas RicardasRahman MahmudurRaitakari OlliRaj ManuRao Sudha RamachandraRamachandran AmbadyRamke JacquelineRamos RafelRampal SanjayRasmussen FinnRedon JosepReganit Paul Ferdinand MRibeiro RobespierreRiboli ElioRigo FernandoWit Tobias F Rinke DeRitti-Dias Raphael MRivera Juan ARobinson Sian MRobitaille CynthiaRodríguez-Artalejo FernandoRodriguez-Perez María del CristoRodríguez-Villamizar Laura ARojas-Martinez RosalbaRojroongwasinkul NipaRomaguera DoraRonkainen KimmoRosengren AnnikaRouse IanRubinstein AdolfoRühli Frank JRui OrnelasRuiz-Betancourt Blanca SandraHorimoto Andrea Rv RussoRutkowski MarcinSabanayagam CharumathiSachdev Harshpal SSaidi OlfaSalanave BenoitMartinez Eduardo SalazarSalomaa VeikkoSalonen Jukka TSalvetti MassimoSánchez-Abanto JoseSans SusanaSantos Diana ASantos OsvaldoSantos Renata Nunes DosSantos RuteSaramies Jouko LSardinha Luis BSarrafzadegan NizalSaum Kai-UweSavva Savvas CScazufca MarciaRosario Angelika SchaffrathSchargrodsky HermanSchienkiewitz AnjaSchmidt Ida MariaSchneider Ione JSchultsz ConstanceSchutte Aletta ESein Aye AyeSen AbhijitSenbanjo Idowu OSepanlou Sadaf GShalnova Svetlana ASharma Sanjib KShaw Jonathan EShibuya KenjiShin Dong WookShin YouchanShiri RahmanSiantar RosalynnSibai Abla MSilva Antonio MSilva Diego Augusto SantosSimon MarySimons JudithSimons Leon ASjostrom MichaelSlowikowska-Hilczer JolantaSlusarczyk PrzemyslawSmeeth LiamSmith Margaret CSnijder Marieke BSo Hung-KwanEugène SobngwiSöderberg StefanSoekatri Moesijanti YeSolfrizzi VincenzoSonestedt EmilySong YiSørensen Thorkild IaSoric MarojeJérome Charles SossaSoumare AichaStaessen Jan AStarc GregorStathopoulou Maria GStaub KasparStavreski BillSteene-Johannessen JosteinStehle PeterStein Aryeh DStergiou George SStessman JochananStieber JuttaStöckl DorisStocks TanjaStokwiszewski JakubStratton GarethStronks KarienStrufaldi Maria WanySun Chien-AnSundström JohanSung Yn-TzSunyer JordiSuriyawongpaisal PaibulSwinburn Boyd ASy Rody GSzponar LucjanTai E ShyongTammesoo Mari-LiisTamosiunas AbdonasTang LineTang XunTanser FrankTao YongTarawneh Mohammed RasoulTarp JakobTarqui-Mamani Carolina BTaylor AnneTchibindat FélicitéTheobald HolgerThijs LutgardeThuesen Betina HTjonneland AnneTolonen Hanna KTolstrup Janne STopbas MuratTopór-Madry RomanTorrent MatiesToselli StefaniaPierre TraissacTrichopoulou AntoniaTrichopoulos DimitriosTrinh Oanh ThTrivedi AtulTshepo LechabaTulloch-Reid Marshall KTuomainen Tomi-PekkaTuomilehto JaakkoTurley Maria LTynelius PerTzotzas ThemistoklisTzourio ChristopheUeda PeterUkoli Flora AmUlmer HannoUnal BelginUusitalo Hannu MtValdivia GonzaloVale SusanaValvi DamaskiniSchouw Yvonne T van DerHerck Koen VanMinh Hoang VanRossem Lenie VanValkengoed Irene Gm VanVanderschueren DirkVanuzzo DiegoVatten LarsVega TomasVelasquez-Melendez GustavoVeronesi GiovanniVerschuren Wm MoniqueVerstraeten RoosmarijnVictora Cesar GViegi GiovanniViet LucieViikari-Juntura EiraVineis PaoloVioque JesusVirtanen Jyrki KSophie Visvikis-SiestViswanathan BharathiVollenweider PeterVoutilainen SariVrdoljak AnaVrijheid MartineWade Alisha NWagner AlineWalton JanetteMohamud Wan Nazaimoon WanWang Ming-DongWang QianWang Ya XingWannamethee S GoyaWareham NicholasWeerasekera DeepaWhincup Peter HWidhalm KurtWidyahening Indah SWiecek AndrzejWijga Alet HWilks Rainford JWilleit JohannWilsgaard TomWojtyniak BogdanWong Jyh EiinWong Tien YinWoo JeanWoodward MarkWu Frederick CWu JianfengWu Shou LingXu HaiquanXu LiangYamborisut UruwanYan WeiliYang XiaoguangYardim NazanYe XingwangYiallouros Panayiotis KYoshihara AkihiroYou Qi ShengYounger-Coleman Novie OYusoff Ahmad FZainuddin Ahmad AZambon SabinaZdrojewski TomaszZeng YiZhao DongZhao WenhuaZheng YingfengZhou MaigengZhu DanZimmermann EstherCisneros And Julio ZuñigaIvana Radić
• Organismes : Institut de Recherche pour le Développement Institut de Recherche pour le Développement Nutrition et Alimentation des Populations aux Suds Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire Nutrition et Alimentation des Populations aux Suds Interactions Gène-Environnement en Physiopathologie Cardio-Vasculaire
• Publié dans eLife le 23/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2016
• Auteurs : Daniel Ă CurcioSamir DelibegovicZaza DemetrashviliBelinda de Ă SimoneSameer DhingraJose J. DiazĂ Isidoro Di CarloAngel DillipSalomone Di SaverioMichael P. Ă DoyleGereltuya DorjAgron DogjaniHervé DupontĂ Soumitra R. EachempatiMushira Abdulaziz EnaniValery N. EgievMutasim M. Ă ElmangoryPaula FerradaJoseph R. FitchettGustavo P. Ă FragaNathalie GuessenndHelen GiamarellouWagih Ă GhnnamGeorge GkiokasStaphanie R. GoldbergĂ Carlos Augusto GomesHarumi GomiManuel Guzman-BlancoĂ Mainul HaqueSonja HansenAndreas HeckerWolfgang R. Ă HeizmannTorsten HerzogAdrien Montcho HodonouSuk-Kyung HongReinhold Ă Kafka-RitschLewis J. KaplanGarima KapoorAleksandar Ă KaramarkovicMartin G. KeesJakub KenigRonald Ă KigubaPeter K. KimYoram KlugerVladimir Ă KhokhaKaoru KoikeKenneth Y. Y. KokVictory KongĂ Matthew C. KnoxKenji InabaArda IsikKatia IskandarRao R. Ă IvaturyMaurizio LabbateFrancesco M. LabricciosaPierre-Francois Ă LaterreRifat LatifiJae Gil LeeĂ Young Ran LeeMarc LeoneAri LeppaniemiYousheng LiStephen Y. Ă LiangTonny LohoMarc MaegeleSydney Ă MalamaHany E. MareiIgnacio Martin-LoechesSanjay MarwahAmos Ă MasseleMichael McfarlaneRenato Bessa MeloĂ Ionut NegoiDavid P. NicolauCarl Erik NordĂ Richard Ofori-AsensoAbdelkarim H. OmariCarlos A. OrdonezĂ Mouaqit OuadiiGerson Alves Pereira JuniorDiego PiazzaĂ Guntars PupelisTimothy Miles RawsonMiran RemsSandro RizoliClaudio Ă RochaBoris SakakhushevMiguel Sanchez-GarciaNorio Ă SatoHelmut A. Segovia LohseGabriele SgangaBoonying Ă SiribumrungwongVishal G. ShelatKjetil SoreideRodolfo Ă SotoPeep TalvingJonathan V. TilsedĂ Jean-Francois TimsitGabriel TruebaNgo Tat TrungJan UlrychHarry Ă Van GoorAndras VereczkeiRavinder S. VohraĂ Imtiaz WaniWaldemar UhlYonghong XiaoKuo-Ching YuanSanoop K. Ă ZachariahJean-Ralph ZaharTanya L. ZakrisonAntonio Ă CorcioneRita M. MelottiClaudio ViscoliĂ Perluigi VialeMassimo SartelliDieter G. WeberEtienne RuppeĂ Matteo BassettiBrian J. WrightLuca AnsaloniFausto CatenaFederico Ă CoccoliniFikri M. Abu-ZidanRaul CoimbraĂ Ernest E. MooreFrederick A. MooreRonald V. MaierJan Ă J. de WaeleAndrew W. KirkpatrickEwen A. GriffithsĂ Christian EckmannAdrian J. BrinkJohn E. MazuskiAddison K. Ă MayRob G. SawyerDominik MertzPhilippe MontraversAnand Ă KumarJason A. RobertsJean-Louis VincentĂ Richard R. WatkinsWarren LowmanBrad SpellbergIain J. Ă AbbottAbdulrashid Kayode AdesunkanmiSara Al-DahirĂ Majdi N. Al-HasanFerdinando AgrestaAsma A. AlthaniĂ Shamshul AnsariRashid AnsumanaGoran AugustinMiklosh BalaZsolt J. Ă BaloghOussama BaraketAneel BhanguĂ Marcelo A. BeltranMichael BernhardWalter L. BifflĂ Marja A. BoermeesterStephen M. BrecherJill R. Cherry-BukowiecĂ Otmar R. BuyneMiguel A. CainzosKelly A. CairnsĂ Adrian Camacho-OrtizSujith J. ChandyAsri Che JusohĂ Alain Chichom-MefireCaroline ColijnFrancesco CorcioneYunfeng Cui
• Organismes : CHU Amiens-Picardie 6th Department of Internal Medicine Department of Anesthesiology and Intensive Care Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes Hartford Hospital Department of Laboratory Medicine Equipe mobile d'infectiologie Service Microbiologie-Hygiène Hospitalière Infectious Diseases Service d'anesthésie - réanimation chirurgicale [CHU Bichat] Université libre de Bruxelles
• Publié dans World Journal of Emergency Surgery le 22/10/2020

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Résumé : Intra-abdominal infections (IAI) are an important cause of morbidity and ă are frequently associated with poor prognosis, particularly in high-risk ă patients. ă The cornerstones in the management of complicated IAIs are timely ă effective source control with appropriate antimicrobial therapy. Empiric ă antimicrobial therapy is important in the management of intra-abdominal ă infections and must be broad enough to cover all likely organisms ă because inappropriate initial antimicrobial therapy is associated with ă poor patient outcomes and the development of bacterial resistance. ă The overuse of antimicrobials is widely accepted as a major driver of ă some emerging infections (such as C. difficile), the selection of ă resistant pathogens in individual patients, and for the continued ă development of antimicrobial resistance globally. The growing emergence ă of multi-drug resistant organisms and the limited development of new ă agents available to counteract them have caused an impending crisis with ă alarming implications, especially with regards to Gram-negative ă bacteria. ă An international task force from 79 different countries has joined this ă project by sharing a document on the rational use of antimicrobials for ă patients with IAIs. The project has been termed AGORA (Antimicrobials: A ă Global Alliance for Optimizing their Rational Use in Intra-Abdominal ă Infections). The authors hope that AGORA, involving many of the world's ă leading experts, can actively raise awareness in health workers and can ă improve prescribing behavior in treating IAIs.

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Fichiers liés : 13017_2016_Article_89.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2016
• Auteurs : Jean-Luc AdamG. Conesa BalbastreJulien FaivreChristophe FurgetR. GuernaneS. KoxJ.S. RealC. SilvestreA. VauthierR. VernetI. BelikovB. HippolyteC. KuhnA. MaireL. MolnarChristelle RoyX. Sanchez CastroV. BarretN. BastidA. Batista CamejoP. CrochetP. DupieuxS. LiX. LopezF. MansoSarah Porteboeuf HoussaisP. RosnetB. VulpescuLaurent AphecetcheA. BaldisseriGuillaume BatigneH. BorelJ. Castillo CastellanosJ.L. CharvetC. CheshkovB. CheynisL. DucrouxMarie GermainJ.-Y. GrossiordA. LardeuxJ. Martin BlancoGines Martinez GarciaL. MassacrierH. Pereira Da CostaPhilippe PillotL. RonfletteY. SchutzAlexandre ShabetaiDiego StoccoB. TeyssierR. TieulentA. UrasM. WangZ. Conesa Del ValleI. DasB. EspagnonC. HadjidakisI. LakomovC. SuireJ. D. Tapia TakakiM. TarhiniL. Valencia Palomo
• Organismes : Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Centre de Calcul de l'IN2P3 Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay
• Publié dans Physics Letters B le 02/11/2020

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Résumé : We present results of a search for two hypothetical strange dibaryon states, i.e. the H-dibaryon and the possible $\overline{\Lambda\mathrm{n}}$ bound state. The search is performed with the ALICE detector in central (0-10%) Pb-Pb collisions at $ \sqrt{s_{\rm{NN}}} = 2.76$ TeV, by invariant mass analysis in the decay modes $\overline{\Lambda\mathrm{n}} \rightarrow \overline{\mathrm{d}} \pi^{+} $ and H-dibaryon $\rightarrow \Lambda \mathrm{p} \pi^{-}$. No evidence for these bound states is observed. Upper limits are determined at 99% confidence level for a wide range of lifetimes and for the full range of branching ratios. The results are compared to thermal, coalescence and hybrid UrQMD model expectations, which describe correctly the production of other loosely bound states, like the deuteron and the hypertriton.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2016
• Auteurs : Diego Sánchez-MartínezPilar LanuzaNatalia GómezAura MuntasellElisa CisnerosManuela MoraruGemma AzacetaAlberto AnelLuis Martinez-LostaoMartin VillalbaLuis PalomeraCarlos VilchesJosé García MarcoJulián Pardo
• Organismes : Universidad de Zaragoza = University of Zaragoza [Saragossa University] = Université de Saragosse Universidad de Zaragoza = University of Zaragoza [Saragossa University] = Université de Saragosse Hospital Universitario Puerta de Hierro-Majadahonda [Madrid, Spain] IMIM-Hospital del Mar Hospital Universitario Puerta de Hierro-Majadahonda [Madrid, Spain] Hospital Universitario Puerta de Hierro-Majadahonda [Madrid, Spain] Aragón Health Research Institute [Zaragoza, Spain] Universidad de Zaragoza = University of Zaragoza [Saragossa University] = Université de Saragosse Universidad de Zaragoza = University of Zaragoza [Saragossa University] = Université de Saragosse Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB) Aragón Health Research Institute [Zaragoza, Spain] IMIM-Hospital del Mar Hospital Universitario Puerta de Hierro-Majadahonda [Madrid, Spain] Universidad de Zaragoza = University of Zaragoza [Saragossa University] = Université de Saragosse
• Publié dans Frontiers in Immunology le 25/10/2020

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Résumé : Mutational status of TP53 together with expression of wild-type (wt) IGHV represents the most widely accepted biomarkers, establishing a very poor prognosis in B-cell chronic lymphocytic leukemia (B-CLL) patients. Adoptive cell therapy using allogeneic HLA-mismatched Natural killer (NK) cells has emerged as an effective and safe alternative in the treatment of acute myeloid and lymphoid leukemias that do not respond to traditional therapies. We have described that allogeneic activated NK cells eliminate hematological cancer cell lines with multidrug resistance acquired by mutations in the apoptotic machinery. This effect depends on the activation protocol, being B-lymphoblastoid cell lines (LCLs) the most effective stimulus to activate NK cells. Here, we have further analyzed the molecular determinants involved in allogeneic NK cell recognition and elimination of B-CLL cells, including the expression of ligands of the main NK cell-activating receptors (NKG2D and NCRs) and HLA mismatch. We present preliminary data suggesting that B-CLL susceptibility significantly correlates with HLA mismatch between NK cell donor and B-CLL patient. Moreover, we show that the sensitivity of B-CLL cells to NK cells depends on the prognosis based on TP53 and IGHV mutational status. Cells from patients with worse prognosis (mutated TP53 and wt IGHV) are the most susceptible to activated NK cells. Hence, B-CLL prognosis may predict the efficacy of allogenic activated NK cells, and, thus, NK cell transfer represents a good alternative to treat poor prognosis B-CLL patients who present a very short life expectancy due to lack of effective treatments.

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Fichiers liés : IRMB 49_P 44_Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells_fimmu-07-00454.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2016
• Auteurs : Alexander AabPedro AbreuMarco AgliettaEun-Joo AhnImen Al SamaraiIvone AlbuquerqueIngomar AllekottePatrick AllisonAlejandro AlmelaJesus Alvarez CastilloJaime Alvarez-MuñizRafael Alves BatistaMichelangelo AmbrosioAmin AminaeiGioacchino Alex AnastasiLuis AnchordoquiSofia AndringaCarla AramoFernando ArquerosNicusor ArseneHernán Gonzalo AsoreyPedro AssisJulien AublinGualberto AvilaNafiun AwalAlina Mihaela BadescuColin BausJim BeattyKarl Heinz BeckerJose A. BellidoC. BeratMario Edoardo BertainaXavier BertouPeter BiermannPierre BilloirSimon G. BlaessAlberto BlancoMiguel BlancoJiri BlazekCarla BleveHans BlümerMartina BoháčováDenise BoncioliCarla BonifaziNataliia BorodaiJeffrey BrackIliana BrancusThomas BretzAriel BridgemanPedro BrogueiraPeter BuchholzAntonio BuenoStijn BuitinkMario BuscemiKaren S. Caballero-MoraBarbara CaccianigaLorenzo CaccianigaMarina CandussoLaurentiu CarameteRossella CarusoAntonella CastellinaGabriella CataldiLorenzo CazonRosanna CesterAlan G. ChavezAndrea ChiavassaJose Augusto ChinellatoJiri ChudobaMarco CilmoRoger W ClayGiuseppe CoccioloRoberta ColalilloAlan ColemanLaura CollicaMaria Rita ColucciaRuben ConceiçãoFernando ContrerasMathew J. CooperAlain CordierStephane CoutuCorbin CovaultJames CroninRichard DallierBruno DanielSergio DassoKai DaumillerBruce R. DawsonRogerio M. de AlmeidaSijbrand J. de JongGiuseppe de MauroJoao de Mello NetoIvan de MitriJaime de OliveiraVitor de SouzaLuis del PeralOlivier DelignyNiraj DhitalClaudio Di GiulioArmando Di MatteoJohana Chirinos DiazMary Lucia Díaz CastroFrancisco DiogoCarola DobrigkeitWendy DoctersJuan Carlos d'OlivoAlexei DorofeevQader Dorosti HasankiadehRita Dos AnjosMaria Teresa DovaJan EbrRalph EngelMartin ErdmannMona ErfaniCarlos O. EscobarJoao EspadanalAlberto EtchegoyenHeino FalckeKe FangGlennys FarrarAnderson FauthNorberto FazziniAndrew P. FergusonBrian FickJuan Manuel FigueiraAlberto FilevichAndrej FilipčičOctavian FratuMartín Miguel FreireToshihiro FujiiBeatriz GarcíaDiego Garcia-GamezDiego Garcia-PintoFlorian GateHartmut GemmekeAlexandru Gherghel-LascuPiera Luisa GhiaUgo GiaccariMarco GiammarchiMaria GillerDariusz GłasChristian GlaserHenry GlassGeraldina GolupMariano Gómez BerissoPrimo F. Gómez VitaleNicolás GonzálezBen GookinJacob GordonAlessio GorgiPeter GorhamPhilippe GouffonNathan GriffithAurelio GrilloTrent D. GrubbFausto GuarinoGermano GuedesMatías Rolf HampelPatricia HansenDiego HarariThomas A. HarrisonSebastian HartmannJohn HartonAndreas HaungsThomas HebbekerDieter HeckPhilipp HeimannAlexander E. HerveGary C. HillCarlos HojvatNicholas HollonEwa HoltPiotr HomolaJörg HörandelPavel HorvathMiroslav HrabovskýDaniel HuberTim HuegeAntonio InsoliaPaula Gina IsarIngolf JandtStefan JansenCecilia JarneJeffrey A. JohnsenMariela JosebachuiliAlex KääpäOlga KambeitzKarl Heinz KampertPeter KasperIgor KatkovBianca KeilhauerErnesto KempRoger KieckhaferHans KlagesMatthias KleifgesJonny KleinfellerRaphael KrauseNicole KrohmDaniel KuempelGasper Kukec MezekNorbert KunkaAlaa Metwaly Kuotb AwadDanielle LahurdLuca LatronicoRobert LauerMarkus LauscherPascal LautridouS. Le CozD. LebrunPaul LebrunMarcelo Augusto Leigui de OliveiraA. Letessier SelvonIsabelle Lhenry-YvonKatrin LinkLuis LopesRebeca LópezAida López CasadoK. LouedecAgustin LuceroMax MalacariManuela MallamaciJennifer MallerDusan MandatPaul MantschAnalisa MariazziVincent MarinIoana MarişGiovanni MarsellaDaniele MartelloHumberto MartinezOscar Martínez BravoDiane MartraireJimmy Masías MezaHermann-Josef MathesSebastian MathysJames MatthewsJohn MatthewsGiorgio MatthiaeDaniela MaurizioEric MayottePeter MazurCarlos MedinaGustavo Medina-TancoRebecca MeissnerVictor MelloDiego MeloAlexander MenshikovStefano MessinaMaria Isabel MichelettiLukas MiddendorfIgnacio A. MinayaLino MiramontiBogdan MitricaLaura Molina-BuenoSilvia MollerachF. MontanetCarlo MorelloMiguel MostafáCelio A. MouraMarcio Aparecido MullerGero MüllerSarah MüllerSergio NavasPetr NecesalLukas NellenAnna NellesJens NeuserPhong H. NguyenMihai Niculescu-OglinzanuMarcus NiechciolLukas NiemietzTim NiggemannDave NitzDalibor NosekVladimir NovotnyLyberis NožkaLuis NúñezLivingstone OchiloFoteini OikonomouAngela OlintoNoelia PachecoDaniel Pakk Selmi-DeiMiroslav PalatkaJuan PallottaPhilipp PapenbreerGonzalo ParenteAlejandra ParraThomas PaulMiroslav PechJan PękalaRodrigo PelayoIuri PepeLorenzo PerroneEmily PetermannChristine PetersSergio PetreraYevgeniy PetrovJamyang PhuntsokRicardo PiegaiaTanguy PierogPablo PieroniMário PimentaValerio PirronelloManuel PlatinoMatthias PlumAlessio PorcelliCzeslaw PorowskiRaul Ribeiro PradoPaolo PriviteraMichael ProuzaEduardo J QuelSven QuerchfeldSean QuinnJulian RautenbergOlivier RavelDiego RavignaniDarius ReinertBenoît RevenuJan RidkyMarkus RissePablo RistoriVincenzo RiziWashington Rodrigues de CarvalhoJorge Rubén Rodriguez RojoMaria Dolores Rodríguez-FríasDmytro RogozinJaime RosadoMarkus RothEsteban RouletAdrian RoveroSteven J. SaffiAlexandra SaftoiuHumberto SalazarAhmed SalehFrancisco Salesa GreusGaetano SalinaJose Sanabria GomezFederico SánchezPatricia Sanchez-LucasEdivaldo Moura SantosEva SantosFred SarazinBiswaijt SarkarRaul SarmentoChristian Sarmiento-CanoRicardo SatoCarlos ScarsoMarkus SchauerViviana ScheriniHarald SchielerDavid SchmidtOlaf ScholtenHarm SchoorlemmerPetr SchovánekFrank G. SchröderAlexander SchulzJohannes SchulzJohannes SchumacherSergio SciuttoAlberto SegretoMariangela SettimoAmir ShadkamRonald C. ShellardGuenter SiglOctavian SimaAndrzej ŚmiałkowskiRadomir ŠmídaGregory SnowPaul SommersSebastian SonntagJ. SorokinRuben SquartiniYogendra N. SrivastavaDenis StancaSamo StaničJames StapletonJaroslaw StasielakMaurice StephanA. StutzFederico SuarezMauricio Suarez DuránTiina SuomijärviA. Daniel SupanitskyMichael SutherlandJohn SwainZbigniew SzadkowskiOscar Alejandro TabordaAlex TapiaAndreas TepeVanessa Menezes TheodoroCharles TimmermansCarlos J. Todero PeixotoGabriel TomaLenka TomankovaBernardo ToméAurelio TonachiniGuillermo Torralba ElipeDiego Torres MachadoPetr TravnicekMarta TriniRalf UlrichMichael UngerMartin UrbanJose F. Valdés GaliciaInes ValiñoLaura ValoreGuus van AarPatrick van BodegomA. M. van den BergSjoert van VelzenArjen van VlietEnrique VarelaBernardo Vargas CárdenasGary VarnerRafael VasquezJose R. VázquezRicardo VázquezDarko VeberičValerio VerziJakub VichaMariela VidelaLuis VillaseñorBrian VlcekSerguei VorobiovHernan WahlbergOscar WainbergDavid WalzAlan WatsonMarc WeberKlaus WeidenhauptAndreas WeindlChristoph WellingFelix WernerAllan WidomLawrence WienckeHenryk WilczyńskiTobias WinchenDavid WittkowskiBrian WundheilerSarka WykesLili YangTolga YapiciAlexey YushkovEnrique ZasDanilo ZavrtanikMarko ZavrtanikArnulfo ZepedaBenedikt ZimmermannMichael ZiolkowskiFrancesca Zuccarello
• Organismes : Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de l'Accélérateur Linéaire Unité Scientifique de la Station de Nançay Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire d'Orsay Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire d'Orsay Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique Subatomique et de Cosmologie
• Publié dans Physical Review Letters le 02/11/2020

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Résumé : We measure the energy emitted by extensive air showers in the form of radio emission in the frequency range from 30 to 80 MHz. Exploiting the accurate energy scale of the Pierre Auger Observatory, we obtain a radiation energy of 15.8 \pm 0.7 (stat) \pm 6.7 (sys) MeV for cosmic rays with an energy of 1 EeV arriving perpendicularly to a geomagnetic field of 0.24 G, scaling quadratically with the cosmic-ray energy. A comparison with predictions from state-of-the-art first-principle calculations shows agreement with our measurement. The radiation energy provides direct access to the calorimetric energy in the electromagnetic cascade of extensive air showers. Comparison with our result thus allows the direct calibration of any cosmic-ray radio detector against the well-established energy scale of the Pierre Auger Observatory.

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Fichiers liés : PhysRevLett.116.241101.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2016
• Auteurs : Jean-Luc AdamLaurent AphecetcheB. AudurierA. BaldisseriGuillaume BatigneI. BelikovH. BorelJ. Castillo CastellanosJ.L. CharvetC. CheshkovB. CheynisL. DucrouxMagali EstienneMarie GermainJ.-Y. GrossiordB. HippolyteA. LardeuxJ. Martin BlancoGines Martinez GarciaL. MassacrierL. MolnarD.A. Moreira De GodoyA. MorrealeH. Pereira Da CostaPhilippe PillotF. RamiL. RonfletteChristelle RoyX. Sanchez CastroAlexandre ShabetaiDiego StoccoB. TeyssierR. TieulentA. UrasR. VernetM. WangG. Conesa BalbastreJulien FaivreChristophe FurgetR. GuernaneS. KoxJ.S. RealC. SilvestreA. VauthierZ. Conesa Del ValleI. DasB. EspagnonC. HadjidakisI. LakomovC. SuireJ. D. Tapia TakakiM. TarhiniL. Valencia Palomo
• Organismes : Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Institut Pluridisciplinaire Hubert Curien Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire de Lyon Institut Pluridisciplinaire Hubert Curien Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut Pluridisciplinaire Hubert Curien Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Institut Pluridisciplinaire Hubert Curien Laboratoire de physique subatomique et des technologies associées Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Centre de Calcul de l'IN2P3 Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay
• Publié dans Physics Letters B le 02/11/2020

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Résumé : The production of the hypertriton nuclei $^{3}_{\Lambda}\mathrm H$ and $^{3}_{\bar{\Lambda}} \overline{\mathrm H}$ has been measured for the first time in Pb-Pb collisions at $\sqrt{s_{\rm NN}}$ = 2.76 TeV with the ALICE experiment at LHC energies. The total yield, d$N$/d$y$ $\times \mathrm{B.R.}_{\left( ^{3}_{\Lambda}\mathrm H \rightarrow ^{3}\mathrm{He},\pi^{-} \right)} = \left( 3.86 \pm 0.77 (\mathrm{stat.}) \pm 0.68 (\mathrm{syst.})\right) \times 10^{-5}$ in the 0-10% most central collisions, is consistent with the predictions from a statistical thermal model using the same temperature as for the light hadrons. The coalescence parameter $B_3$ shows a dependence on the transverse momentum, similar to the $B_2$ of deuterons and the $B_3$ of $^{3}\mathrm{He}$ nuclei. The ratio of yields $S_3$ = $^{3}_{\Lambda}\mathrm H$/($^{3}\mathrm{He}$ $\times \Lambda/\mathrm{p}$) was measured to be $S_3$ = 0.60 $\pm$ 0.13 (stat.) $\pm$ 0.21 (syst.) in 0-10% centrality events; this value is compared to different theoretical models. The measured $S_3$ is fully compatible with thermal model predictions. The measured $^{3}_{\Lambda}\mathrm H$ lifetime, $ \tau = 181^{+54}_{-39} (\mathrm{stat.}) \pm 33 (\mathrm{syst.})\ \mathrm{ps}$ is compatible within 1$\sigma$ with the world average value.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2016
• Auteurs : Jean-Luc AdamG. Conesa BalbastreJulien FaivreChristophe FurgetR. GuernaneJ.S. RealC. SilvestreA. VauthierR. VernetI. BelikovB. HippolyteC. KuhnA. MaireL. MolnarChristelle RoyX. Sanchez CastroV. BarretN. BastidA. Batista CamejoP. CrochetP. DupieuxS. LiX. LopezF. MansoSarah Porteboeuf HoussaisP. RosnetB. VulpescuLaurent AphecetcheB. AudurierA. BaldisseriGuillaume BatigneH. BorelJ. Castillo CastellanosJ.-L. CharvetC. CheshkovB. CheynisL. DucrouxMarie GermainJ.-Y. GrossiordA. LardeuxJ. Martin BlancoL. MassacrierD.A. Moreira De GodoyA. MorrealeH. Pereira Da CostaPhilippe PillotL. RonfletteY. SchutzAlexandre ShabetaiDiego StoccoB. TeyssierR. TieulentA. UrasM. WangZ. Conesa Del ValleI. DasB. EspagnonC. HadjidakisI. LakomovC. SuireJ. D. Tapia TakakiM. TarhiniL. Valencia Palomo
• Organismes : Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Centre de Calcul de l'IN2P3 Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de Physique Corpusculaire - Clermont-Ferrand Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire de Lyon Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Institut de Physique Nucléaire de Lyon Laboratoire de physique subatomique et des technologies associées Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay Institut de Physique Nucléaire d'Orsay
• Publié dans Physical Review C le 02/11/2020

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Résumé : Transverse momentum ($p_{\rm{T}}$) spectra of pions, kaons, and protons up to $p_{\rm{T}} = 20$ GeV/$c$ have been measured in Pb-Pb collisions at $\sqrt{s_{\rm NN}} = 2.76$ TeV using the ALICE detector for six different centrality classes covering 0-80%. The proton-to-pion and the kaon-to-pion ratios both show a distinct peak at $p_{\rm{T}} \approx 3$ GeV/$c$ in central Pb-Pb collisions that decreases towards more peripheral collisions. For $p_{\rm{T}} > 10$ GeV/$c$, the nuclear modification factor is found to be the same for all three particle species in each centrality interval within systematic uncertainties of 10-20%. This suggests there is no direct interplay between the energy loss in the medium and the particle species composition in the hard core of the quenched jet. For $p_{\rm{T}} < 10$ GeV/$c$, the data provide important constraints for models aimed at describing the transition from soft to hard physics.

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