Diego SANCHEZ

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• Type de publi. : Article dans une revue
• Date de publi. : 12/11/2024
• Auteurs : Adrián Palencia-CamposLaura Ruiz-CañasMarcelina Abal-SanisidroJuan Carlos López-GilSandra Batres-RamosSofia Mendes SaraivaBalbino YagüeDiego NavarroDiego NavarroSonia AlcaláJuan A RubioloNadège BidanLaura SánchezSimona MuraPatrick C HermannMaría de la FuenteBruno Sainz
• Organismes : Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain] Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain] Centro de Investigación Biomédica en Red de Cáncer Complejo Hospitalario Universitario de Santiago de Compostela [ESpaña] = USC University Hospital Complex [Spain] = Centre hospitalier universitaire de Saint-Jacques-de-Compostelle [Espagne] Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain] Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain] Instituto Ramon y Cajal de Investigacion Sanitaria [Madrid, Spain] Instituto de Investigación Sanitaria de Santiago de Compostela / Health Research Institute of Santiago de Compostela Centro de Investigación Biomédica en Red de Cáncer Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain] Evaluation non destructive des structures et des matériaux Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain] Universidad Autónoma de Madrid Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain] Instituto Ramon y Cajal de Investigacion Sanitaria [Madrid, Spain] Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain] Universidade de Santiago de Compostela [España] = University of Santiago de Compostela [Spain] = Université de Saint-Jacques-de-Compostelle [Espagne] Institut Galien Paris-Saclay Universidade de Santiago de Compostela [España] = University of Santiago de Compostela [Spain] = Université de Saint-Jacques-de-Compostelle [Espagne] Institut Galien Paris-Saclay Universität Ulm - Ulm University [Ulm, Allemagne] Centro de Investigación Biomédica en Red de Cáncer Instituto de Investigaciones Biomédicas Alberto Sols [Madrid, Spain]
• Publié dans Journal of Nanobiotechnology le 24/10/2020

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Résumé :

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Fichiers liés : Main text_Reprogramming Tumor-Associated Macrophages with Lipid Nanosystems Reduces PDAC Tumor Burden and Liver Metastasis_ref.pdf

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Source

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• Type de publi. : Article dans une revue
• Date de publi. : 01/11/2024
• Auteurs : Bin ZhouArchie RaynerEdward GreggKate ShefferRodrigo Carrillo-LarcoJames BennettJonathan ShawChristopher PaciorekRosie SingletonAna Barradas PiresGretchen StevensGoodarz DanaeiVictor Pf LhosteNowell PhelpsRachel HeapLakshya JainYse d'Ailhaud de BrisisAgnese GaleazziAndre KengneAnu MishraNayu IkedaHsien-Ho LinCarlos Aguilar-SalinasRanjit Mohan AnjanaHabiba Ben RomdhaneKairat DavletovShubash GanapathyChristin HeidemannYousef Saleh KhaderYoung-Ho KhangAvula LaxmaiahJean Claude N MbanyaViswanathan MohanKm Venkat NarayanMeda PavkovEugène SobngwiAlisha WadeNovie Younger-ColemanTomasz ZdrojewskiLeandra Abarca-GómezMohsen Abbasi-KangevariHanan Abdul RahimNiveen Abu-RmeilehShalkar AdambekovRobert AdamsWichai AekplakornShoaib AfzalImelda AgdeppaJavad Aghazadeh-AttariCharles AgyemangNoor Ani AhmadAli AhmadiNaser AhmadiNastaran AhmadiSoheir AhmedWolfgang AhrensKamel AjlouniSarah Al-HamliHalima Al-HinaiJawad Al-LawatiDeena Al AsfoorMonira AlaroujFadia AlbuhairanShahla AldhukairMohamed AliMohammed AliAnna AlievaFarbod AlinezhadAbdullah AlkandariAla'A AlkerwiEman AlyDeepak AmarapurkarLars Bo AndersenSigmund AnderssenDolores AndradeAlireza Ansari-MoghaddamHajer Aounallah-SkhiriJoana AraújoTahir ArisRaphael ArkuNimmathota ArlappaKrishna AryalThor AspelundFelix AssahBatyrbek AssembekovShiu Lun Au YeungJuha AuvinenMária AvdičováKishwar AzadAna AzevedoMohsen Azimi-NezhadFereidoun AziziFlora BacopoulouNagalla BalakrishnaYulia BalanovaMohamed BamoshmooshMaciej BanachPiotr BandoszJosé BanegasCarlo BarbagalloAlberto BarceloMaja BaretićLena BarreraMarta BarretoAbdul BasitAnwar BatiehaAline BatistaLouise BaurAntonisamy BelavendraTheodora BenedekMikhail BenetMichaela BenzevalSalim BerkinbayevAntonio Bernabe-OrtizXimena Berrios CarrasolaHeloísa BettiolAugustin BeybeySantosh BhargavaYufang BiElysée Claude Bika LeleMukharram BikbovBihungum BistaPeter BjerregaardEspen BjertnessMarius BjertnessCecilia BjörkelundKatia BlochAnneke BlokstraMartin BobakBernhard BoehmJose BoggiaCarlos BoissonnetStig BojesenMarialaura BonaccioAlice Bonilla-VargasHerman BorghsSteve BotombaPascal BovetImperia BrajkovichHermann BrennerLizzy BrewsterGarry BrianYajaira BriceñoMiguel BritoGloria BuenoAnna BuggeFrank BuntinxAntonio Cabrera de LeónRoberta CaixetaGünay CanAna Paula C CândidoMario CapanzanaNaděžda ČapkováEduardo CapuanoRocco CapuanoVincenzo CapuanoViviane CardosoAxel CarlssonFelipe CasanuevaLaura CensiCharalambos ChadjigeorgiouParinya ChamnanSnehalatha ChamukuttanQueenie ChanFadi CharcharNish ChaturvediChien-Jen ChenHuashuai ChenLong-Sheng ChenChing-Yu ChengBahman CheraghianAngela ChetritShu-Ti ChiouMaría-Dolores ChirlaqueJerzy ChudekRenata CifkovaMassimo CirilloFrank ClaessensJanine ClarkeEmmanuel CohenHans ConcinCyrus CooperCojocaru CosminSimona CostanzoMelanie CowanChris CowellAmelia CrampinAna CrujeirasJuan CruzFelipe CureauSarah CuschieriGraziella d'ArrigoEleonora d'OrsiHaroldo da Silva-FerreiraJean DallongevilleAlbertino DamascenoRachel DanknerSaeed DastgiriLuc DauchetAmalia de CurtisGiovanni de GaetanoStefaan de HenauwDavid de RidderMohan DeepaVincent Jr DegennaroStefaan DemarestElaine DennisonValérie DeschampsMeghnath DhimalZivka DikaShirin DjalaliniaChiara DonfrancescoMaria DorobantuNico DraganoWojciech DrygasShufa DuYong DuCharmaine DuantePriscilla DubozRosemary DudaAnar DushpanovaVilnis DzerveElzbieta Dziankowska-ZaborszczykNarges EbrahimiRicky EddieEbrahim EftekharVasiliki EfthymiouEruke EgbagbeRobert EggertsenSareh EghtesadClara Ladi EjembiMohammad El-KhateebJalila El AtiDenise Eldemire-ShearerRoberto ElosuaOfem EnangRajiv ErasmusCihangir EremGul ErgorLouise EriksenJohan ErikssonAli EsmaeiliRoger EvansGuy FagherazziNoushin FahimfarIldar FakhradiyevAlbina FakhretdinovaCaroline FallElnaz FaramarziMojtaba FarjamFarshad FarzadfarYosef FarziMohammad Reza FattahiAsher FawwadFrancisco Felix-RedondoTrevor FergusonDaniel Fernández-BergésDesha FernandoThomas FerraoMarika FerrariMarco FerrarioCatterina FerreccioEldridge FerrerEdith Jm FeskensGünther FinkDavid FloodMaria ForsnerSandrine Fosse-EdorhEdward FottrellHeba FouadDamian FrancisGuillermo FronteraIsti FujiatiMatsuda FumihikoTakuro FurusawaZbigniew GaciongFabio GalvanoSarah GarnettJean-Michel GaspozMagda GasullAndrea GazzinelliUlrike GehringEbrahim GhaderiSeyyed-Hadi GhamariAli GhanbariErfan GhasemiOana-Florentina Gheorghe-FroneaAnup GhimireAlessandro GialluisiSimona GiampaoliFrancesco GianfagnaTiffany GillJonathan GiovannelliGlen GironellaAleksander GiwercmanMarcel GoldbergDavid GoltzmanAleksandra GomulaHelen GonçalvesMauer GonçalvesDavid Gonzalez-ChicaMarcela Gonzalez-GrossJuan González-RivasAngel GonzalezAtsushi GotoFrederic GottrandDušan GrafnetterMaria GrammatikopoulouAndriene GrantAnne Sameline GrimsgaardTomasz GrodzickiAnders GrøntvedGiuseppe GrossoDongfeng GuVilmundur GudnasonRamiro GuerreroIdris GuessousUnjali GujralRajeev GuptaLaura GutierrezXinyi GweeSeongjun HaRosa HaghshenasHamid HakimiIan HambletonBehrooz HamzehDominique HangeSari HantunenJie 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KalmatayevaOfra Kalter-LeiboviciArgyro KarakostaKhem KarkiMarzieh KatibehPrasad KatulandaJussi KauhanenGyulli KazakbaevaFrançois KazeCalvin KeSirkka Keinänen-KiukaanniemiRoya KelishadiMaryam KeramatiMathilde KerstingKazem KhalagiArsalan KhaledifarDavood KhaliliBahareh KheiriMotahareh KheradmandAlireza Khosravi FarsaniUrsula Kiechl-KohlendorferSophia KiechlStefan KiechlHyeon Chang KimAndrew KingstonHeidi KlakkJana KlanovaMichael KnoflachPatrick KolsterenJürgen KönigRaija KorpelainenPaul KorrovitsJelena KosSeppo KoskinenSudhir KowlessurSlawomir KozielWolfgang KratzerSusi KriemlerPeter Lund KristensenSteinar KrokstadDaan KromhoutRuzena KubinovaUrho KujalaMukhtar KulimbetVaitheeswaran KulothunganMeena KumariVladimir KutsenkoCatherine KyobutungiQuang Ngoc LaTiina LaatikainenDemetre LabadariosCarl LachatYoucef LaidLachmie LallAnne LangstedTiina LankilaVera LanskaGeorg LappasBagher LarijaniTint Swe LattMartino LaurenziGwenaëlle Le CorollerJeannette LeeTerho LehtimäkiDaniel LemogoumGabriel LeungCharlie LimWei-Yen LimM Fernanda Lima-CostaYi-Jing LinLars LindLauren LissnerLiping LiuXiaotian LiuWei-Cheng LoHelle-Mai LoitEsther Lopez-GarciaTania LopezJosé Eugenio LozanoDalia LuksieneAnnamari LundqvistNuno LunetThomas LungMichala LustigováGuansheng MaGeorge Ll Machado-CoelhoAristides Machado-RodriguesEnguerran MaciaLuisa MacieiraAhmed MadarGladys MaestreStefania MaggiDianna MaglianoEmmanuella MagriplisGowri MahasampathBernard MaireMarcia MakdisseKonstantinos MakrilakisMohammad-Reza MalekpourFatemeh MalekzadehReza MalekzadehSofia MalyutinaLynell ManiegoYannis ManiosFariborz Mansour-GhanaeiEnzo ManzatoMala Ali MapatanoAnie MarcilFrancisco MardonesPaula MargozziniPedro Marques-VidalLarissa Pruner MarquesReynaldo MartorellLuis MascarenhasMannix Masimango ImaniMasoud MasinaeiShariq MasoodiEllisiv MathiesenPrashant MathurTandi MatshaAnselmo Mc Donald PossoShelly McfarlaneStephen McgarveyScott McleanBreige McnultySounnia Mediene BenchekorKirsten MehligAmir Houshang MehrparvarJesus MelgarejoFabián MéndezAna Maria B MenezesAlibek MerekeIndrapal MeshramDiane MetoNathalie MichelsCláudia MindericoGk MiniJuan Francisco MiquelJ Jaime MirandaMohammad Reza MirjaliliDaphne MirkopoulouPietro ModestiSahar Saeedi MoghaddamKazem MohammadMohammad Reza MohammadiZahra MohammadiNoushin MohammadifardReza MohammadpourhodkiMuhammad Fadhli Mohd YusoffIraj MohebbiNiels MøllerDénes MolnárAmirabbas MomenanRoger Montenegro MendozaMahmood MoosazadehFarhad MoradpourAlain MorejonLuis MorenoKaren MorganSuzanne MorinGeorge MoschonisAlireza MoslemMildrey MosqueraMalgorzata MossakowskaAya MostafaSeyed-Ali MostafaviEugen MotaJorge MotaMaria MotaMohammad Esmaeel MotlaghJorge MottaKelias MsyambozaThet Thet MuMaria MuiesanPatricia MunroeJaakko MursuKamarul Imran MusaNorlaila MustafaMuel Telo Mc MuyerIraj NabipourGabriele NagelBalkish NaiduFarid NajafiJana NámešnáEi Ei K NangVinay NangiaTake NaseriAna Navarro-RamírezNareemarn NeelapaichitAzim NejatizadehIlona NenkoFlavio NerviTze Pin NgChung NguyenNguyen NguyenQuang Ngoc NguyenMichael NiPeng NieRamfis Nieto-MartínezGuang NingToshiharu NinomiyaNobuo NishiMarianna NoaleOscar NoboaMitsuhiko NodaBørge NordestgaardDavide NotoMohannad Al NsourIrfan NuhoğluMoffat NyirendaTerence O'NeillKyungwon OhRyutaro OhtsukaMohd Azahadi OmarAltan OnatSok King OngObinna OnodugoPedro OrdunezRui OrnelasPedro OrtizClive OsmondAfshin OstovarJohanna OteroCharlotte OttendahlAkaninyene OtuEllis Owusu-DaboElena PahomovaLuigi PalmieriWen-Harn PanDemosthenes PanagiotakosSonghomitra Panda-JonasZengchang PangFrancesco PanzaMariela PaoliSuyeon ParkMahboubeh ParsaeianChona PatalenNikhil PatelRaimund PechlanerIvan PećinJoão PedroSergio Viana PeixotoMarkku PeltonenAlexandre PereiraThaliane Mayara Pessôa dos PrazeresNiloofar PeykariModou Cheyassin PhallSon Thai PhamRafael PichardoIris PigeotHynek PikhartAida PilavPavel PilerFreda PitakakaAleksandra PiwonskaAndreia PizarroPedro Plans-RubióSilvia PlataBarry PopkinMiquel PortaAnil PoudyalFarhad PourfarziAkram PourshamsHossein PoustchiDorairaj PrabhakaranRajendra PradeepaAlison PriceJacqueline PriceRui ProvidenciaJardena PuderSoile PuhakkaMargus PunabQing QiaoMostafa QorbaniHedley QuintanaTran Quoc BaoRicardas RadisauskasSalar RahimikazerooniOlli RaitakariAmbady RamachandranManuel Ramirez-ZeaJacqueline RamkeElisabete RamosRafel RamosLekhraj RampalSanjay RampalSheena RamsayDaniel Rangel ReinaRavindra Rannan-EliyaMohammad-Mahdi RashidiJosep RedonJane Dp RennerCézane ReuterLuis RevillaNegar RezaeiAbbas RezaianzadehYeunsook RhoFernando RigoLeanne RileyUlf RisérusReina RoaLouise RobinsonWendy Rodríguez-AndersonFernando Rodríguez-ArtalejoMaría del Cristo Rodriguez-PerezLaura Rodríguez-VillamizarAndrea RodríguezUlla RoggenbuckPeter RohloffRosalba Rojas-MartinezElisabetta RomeoAnnika RosengrenJoel Gr RoyAdolfo RubinsteinMaria Ruiz-CastellPaola RussoPetra RustMarcin RutkowskiCharumathi SabanayagamHamideh SabbaghiHarshpal SachdevAlireza SadjadiAli Reza SafarpourSare SafiSaeid SafiriMohammad Hossien SaghiOlfa SaidiSatoko SakataNader SakiSanja ŠalajBenoit SalanaveJukka SalonenMassimo SalvettiJose Sánchez-AbantoDiana SantosLèlita SantosMaria Paula SantosRute SantosTamara SantosJouko SaramiesLuis SardinhaNizal SarrafzadeganYoko SatoKai-Uwe SaumStefan SavinNorie SawadaMariana SbarainiMarcia ScazufcaBeatriz SchaanHerman SchargrodskyChrista Scheidt-NaveSabine SchipfAmand Floriaan SchmidtBörge SchmidtCarsten SchmidtPeter SchnohrCatherine Mary SchoolingBen SchöttkerSara SchrammSylvain SebertMoslem SedaghattalabAye Aye SeinAbhijit SenSadaf SepanlouJennifer ServaisRonel SewpaulSvetlana ShalnovaSeyed Morteza ShamshirgaranCoimbatore Subramaniam ShanthiraniMaryam SharafkhahSanjib SharmaAlmaz SharmanAmaneh ShayanradAli Akbar ShayestehKenji ShibuyaHana Shimizu-FurusawaRahman ShiriMarat ShoranovNamuna ShresthaKhairil Si-RamleeAlfonso SianiMark SiednerDiego Augusto Santos SilvaXueling SimMary SimonJudith SimonsLeon SimonsMichael SjöströmJolanta Slowikowska-HilczerPrzemysław SlusarczykLiam SmeethStefan SöderbergAgustinus SoemantriVincenzo SolfrizziMohammad Hossein SomiAïcha SoumaréAlfonso Sousa-PozaMafalda Sousa-UvaKaren SparrenbergerJan StaessenAndreas StangBill StavreskiJostein Steene-JohannessenPeter StehleAryeh SteinJochanan StessmanJakub StokwiszewskiKarien StronksMilton Suarez-OrtegónPhalakorn SuebsamranMachi SukaChien-An SunJianping SunJohan SundströmPaibul SuriyawongpaisalRené Charles SylvaE Shyong TaiFurusawa TakuroAbdonas TamosiunasEng Joo TanBaimakhan TanabayevNikhil TandonMohammed Rasoul TarawnehCarolina Tarqui-MamaniAnne TaylorTania TelloYih Chung ThamKr ThankappanHolger TheobaldXenophon TheodoridisNihal ThomasAmanda ThriftErik TimmermansHanna TolonenJanne TolstrupMaciej TomaszewskiMurat TopbasMichael TornaritisMaties TorrentLaura Torres-ColladoGiota TouloumiPierre TraissacAreti TriantafyllouOanh Th TrinhYu-Hsiang TsaoThomas TsiampalisShoichiro TsuganeJohn TuiteleAzaliia TuliakovaMarshall Tulloch-ReidTomi-Pekka TuomainenMaria TurleyEvangelia TzalaChristophe TzourioPeter UedaEunice UgelFlora Am UkoliHanno UlmerHannu Mt UusitaloGonzalo ValdiviaDamaskini ValviRob van DamBert-Jan van den BornJohan van der HeydenHoang van MinhLenie van RossemNatasja van SchoorIrene Gm van ValkengoedDirk VanderschuerenDiego VanuzzoAnette VarboSenthil VasanTomas VegaToomas VeidebaumGustavo Velasquez-MelendezCharlotte VerdotGiovanni VeronesiRoosmarijn VerstraetenCesar VictoraLucie VietLuis VillarroelJesus VioqueJyrki VirtanenBharathi ViswanathanPeter VollenweiderAri VoutilainenMartine VrijheidJanette WaltonWan Mohamad Wan BebakarWan Nazaimoon Wan MohamudChongjian WangHuijun WangNingli WangQian WangWeiqing WangYa Xing WangYi-Ren WangYing-Wei WangS Goya WannametheeKaren Webster-KerrNiels WedderkoppWenbin WeiLeo WestburyPeter WhincupKurt WidhalmIndah WidyaheningAndrzej WięcekNilmini WijemunigeRainford WilksKarin WilleitPeter WilleitTom WilsgaardBogdan WojtyniakRoy Wong-McclureAndrew WongEmily WongMark WoodwardChao-Chun WuFrederick WuHaiquan XuLiang XuYu XuNor Azwany YaacobLi YanWeili YanTabara YasuharuChao-Yu YehMoein YoosefiAkihiro YoshiharaSan-Lin YouYu-Ling YuAhmad Faudzi YusoffAhmad ZainuddinFarhad ZamaniSabina ZambonAntonis ZampelasAbdul Hamid ZargarKo Ko ZawTajana Zeljkovic VrkicYi ZengBing ZhangLei ZhangLuxia ZhangZhen-Yu ZhangMing-Hui ZhaoWenhua ZhaoBekbolat ZholdinPaul ZimmetMarie ZinsEmanuel ZittNada ZoghlamiJulio Zuñiga CisnerosMajid Ezzati
• Organismes : University of Chinese Academy of Sciences [Beijing] Shanghai Institute of Biochemistry and Cell Biology [Shanghai, China] CSIRO Environment Business Unit Imperial College London Cohortes épidémiologiques en population
• Publié dans The Lancet le 02/11/2020

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Résumé : Summary Background Diabetes can be detected at the primary health-care level, and effective treatments lower the risk of complications. There are insufficient data on the coverage of treatment for diabetes and how it has changed. We estimated trends from 1990 to 2022 in diabetes prevalence and treatment for 200 countries and territories. Methods We used data from 1108 population-representative studies with 141 million participants aged 18 years and older with measurements of fasting glucose and glycated haemoglobin (HbA1c), and information on diabetes treatment. We defined diabetes as having a fasting plasma glucose (FPG) of 7·0 mmol/L or higher, having an HbA1c of 6·5% or higher, or taking medication for diabetes. We defined diabetes treatment as the proportion of people with diabetes who were taking medication for diabetes. We analysed the data in a Bayesian hierarchical meta-regression model to estimate diabetes prevalence and treatment. Findings In 2022, an estimated 828 million (95% credible interval [CrI] 757–908) adults (those aged 18 years and older) had diabetes, an increase of 630 million (554–713) from 1990. From 1990 to 2022, the age-standardised prevalence of diabetes increased in 131 countries for women and in 155 countries for men with a posterior probability of more than 0·80. The largest increases were in low-income and middle-income countries in southeast Asia (eg, Malaysia), south Asia (eg, Pakistan), the Middle East and north Africa (eg, Egypt), and Latin America and the Caribbean (eg, Jamaica, Trinidad and Tobago, and Costa Rica). Age-standardised prevalence neither increased nor decreased with a posterior probability of more than 0·80 in some countries in western and central Europe, sub-Saharan Africa, east Asia and the Pacific, Canada, and some Pacific island nations where prevalence was already high in 1990; it decreased with a posterior probability of more than 0·80 in women in Japan, Spain, and France, and in men in Nauru. The lowest prevalence in the world in 2022 was in western Europe and east Africa for both sexes, and in Japan and Canada for women, and the highest prevalence in the world in 2022 was in countries in Polynesia and Micronesia, some countries in the Caribbean and the Middle East and north Africa, as well as Pakistan and Malaysia. In 2022, 445 million (95% CrI 401–496) adults aged 30 years or older with diabetes did not receive treatment (59% of adults aged 30 years or older with diabetes), 3·5 times the number in 1990. From 1990 to 2022, diabetes treatment coverage increased in 118 countries for women and 98 countries for men with a posterior probability of more than 0·80. The largest improvement in treatment coverage was in some countries from central and western Europe and Latin America (Mexico, Colombia, Chile, and Costa Rica), Canada, South Korea, Russia, Seychelles, and Jordan. There was no increase in treatment coverage in most countries in sub-Saharan Africa; the Caribbean; Pacific island nations; and south, southeast, and central Asia. In 2022, age-standardised treatment coverage was lowest in countries in sub-Saharan Africa and south Asia, and treatment coverage was less than 10% in some African countries. Treatment coverage was 55% or higher in South Korea, many high-income western countries, and some countries in central and eastern Europe (eg, Poland, Czechia, and Russia), Latin America (eg, Costa Rica, Chile, and Mexico), and the Middle East and north Africa (eg, Jordan, Qatar, and Kuwait). Interpretation In most countries, especially in low-income and middle-income countries, diabetes treatment has not increased at all or has not increased sufficiently in comparison with the rise in prevalence. The burden of diabetes and untreated diabetes is increasingly borne by low-income and middle-income countries. The expansion of health insurance and primary health care should be accompanied with diabetes programmes that realign and resource health services to enhance the early detection and effective treatment of diabetes. Funding UK Medical Research Council, UK Research and Innovation (Research England), and US Centers for Disease Control and Prevention.

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Fichiers liés : NCD Diabète, Lancet 2024.pdf

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Source

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 15/10/2024
• Auteurs : Armen TumasyanWolfgang AdamJanik Walter AndrejkovicThomas BergauerSuman ChatterjeeKonstantinos DamanakisMarko DragicevicAlberto Escalante del VallePriya Sajid HussainManfred JeitlerNatascha KrammerLukas LechnerDietrich LikoIvan MikulecPeter PaulitschFlorian Michael PittersJochen SchieckRobert SchöfbeckDennis SchwarzMangesh SonawaneSebastian TemplWolfgang WaltenbergerClaudia-Elisabeth WulzMohamed Rashad DarwishTahys JanssenTomas KelloHaifa Rejeb SfarPierre van MechelenEmil Sørensen BolsJorgen d'HondtAlexandre de MoorMartin DelcourtHesham El FahamSteven LowetteSeth MoortgatAlexander MortonDenise MüllerAbanti Ranadhir SahasransuStefaan TavernierWalter van DoninckDavid VanneromBarbara ClerbauxGilles de LentdeckerLaurent FavartDmytro HohovJohny JaramilloKyeongpil LeeMostafa MahdavikhorramiInna MakarenkoAndrea MalaraSantiago ParedesLaurent PétréNicolas PostiauLaurent ThomasMax Vanden BemdenCatherine Vander VeldePascal VanlaerDidar DoburJoscha KnolleLuka LambrechtGianny MestdachCésar RendónAmrutha SamalanKirill SkovpenMichael TytgatNiels van den BosscheBasile VermassenLiam WezenbeekAnna BeneckeGiacomo BrunoFlorian Joel J BuryClaudio CaputoPieter DavidChristophe DelaereIzzeddin Suat DonertasAndrea GiammancoKhawla JaffelSandhya JainVincent LemaitreKuntal MondalAngela TaliercioTu Thong TranPietro VischiaSébastien WertzGilvan AlvesEduardo CoelhoCarsten HenselArthur MoraesPatricia Rebello TelesWalter Luiz Aldá JúniorMiguel Alves Gallo PereiraMapse Barroso Ferreira FilhoHelena Brandao MalbouissonWagner CarvalhoJose ChinellatoEliza Melo da CostaGustavo Gil da SilveiraDilson de Jesus DamiaoVitor dos Santos SousaSandro Fonseca de SouzaJordan MartinsClemencia Mora HerreraKevin Mota AmariloLuiz MundimHelio NogimaAlberto SantoroSheila Mara Silva Do AmaralAndre SznajderMauricio ThielAntonio Vilela PereiraCesar Augusto BernardesLuigi CalligarisThiago TomeiEduardo de Moraes GregoresPedro G MercadanteSergio F NovaesSandra PadulaAleksandar AleksandrovGeorgy AntchevRoumyana HadjiiskaPlamen IaydjievMilena MishevaMircho RodozovMariana ShopovaGeorgi SultanovAnton DimitrovTodor IvanovLeander LitovBorislav PavlovPeicho PetkovAnton PetrovElton ShumkaShalini ThakurTongguang ChengTahir JavaidMonika MittalLi YuanMuhammad AhmadGerry BauerZhen HuSamet LezkiKai YiGuo-Ming ChenHe-Sheng ChenMingshui ChenFabio IemmiChun-Hua JiangAnshul KapoorHongbo LiaoZhenan LiuVukasin MilosevicFabio MontiRamkrishna SharmaJunquan TaoJoshuha Thomas-WilskerJin WangHuaqiao ZhangJingzhou ZhaoAntonis AgapitosYing AnYong BanAndrew LevinCongqiao LiQiang LiXudong LyuYajun MaoSi-Jin QianXiaohu SunDayong WangJie XiaoHeng YangMeng LuZhengyun YouNan LuXuyang GaoDuncan LeggatHideki OkawaYu ZhangZhen LinChenfeng LuMeng XiaoCarlos AvilaDiego Andres Barbosa TrujilloAndrés CabreraCarlos FlorezJorge FragaJhovanny Mejia GuisaoFelipe RamirezManuel RodriguezJosé David Ruiz AlvarezDuje GiljanovicNikola GodinovicDamir LelasIvica PuljakZeljko AntunovicMarko KovacToni SculacVuko 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Résumé : Correlations between azimuthal anisotropy and mean transverse momentum of charged particles in proton-proton (pp), proton-lead (pPb), and peripheral lead-lead (PbPb) collisions are presented as a function of charged particle multiplicity. The pp, pPb and PbPb collision data were collected using the CMS detector at the LHC with a center-of-mass energy per nucleon pair of 13, 8.16 and 5.02 TeV, respectively. The two- and four-particle cumulants for the second- and third-order Fourier anisotropy harmonics are correlated with the mean transverse momentum of charged particles on an event-by-event basis. In pp and pPb systems, the observed correlation coefficients based on two-particle cumulants are found to change from negative to positive values as the charged particle multiplicity decreases. The sign changes disappear when the correlated particles are required to be further apart in pseudorapidity. Additionally, no sign changes in correlation coefficients are observed when employing four-particle cumulants. Models incorporating initial-state gluon saturation and final-state hydrodynamic evolutions are compared to pPb data and the predicted sign changes are not observed.

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Source

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• Type de publi. : Article dans une revue
• Date de publi. : 02/10/2024
• Auteurs : Philipp SchlegelYijie YinAlexander Shakeel BatesSven DorkenwaldKatharina EichlerPaul BrooksDaniel HanMarina GkantiaMarcia dos SantosEva MunnellyGriffin BadalamenteLaia Serratosa CapdevilaVarun SaneAlexandra FragniereLadann KiassatMarkus PleijzierTomke StürnerImaan TamimiChristopher DunneIrene SalgarellaAlexandre JavierSiqi FangEric PerlmanTom KazimiersSridhar JagannathanArie MatsliahAmy SterlingSzi-Chieh YuClaire MckellarKrzysztof KrukDoug BlandZairene LenizoAustin BurkeKyle Patrick WillieAlexander BatesNikitas SerafetinidisNashra HadjerolRyan WillieBen SilvermanJohn Anthony OchoJoshua BañezRey Adrian CandiladaJay GagerAnne KristiansenNelsie PanesArti YadavRemer TancontianShirleyjoy SeronaJet Ivan DolorosaKendrick Joules VinsonDustin GarnerRegine SalemAriel DagohoyJaime SkeltonMendell LopezThomas StocksAnjali PandeyDarrel Jay AkiatanJames HebditchCelia DavidDharini SapkalShaina Mae MonungolhVarun SaneMark Lloyd PielagoMiguel AlberoJacquilyn LaudeMárcia dos SantosDavid DeutschZeba VohraKaiyu WangAllien Mae GogoEmil KindAlvin Josh MandahayChereb MartinezJohn David AsisChitra NairDhwani PatelMarchan ManaytayClyde Angelo LimPhilip Lenard AmpoMichelle Darapan PantujanDaril BautistaRashmita RanaJansen SeguidoBhargavi ParmarJohn Clyde SaguimpaMerlin MooreMarkus PleijzierMark LarsonJoseph HsuItisha JoshiDhara KakadiyaAmalia BraunCathy PilapilKaushik ParmarQuinn VanderbeckChristopher DunneEva MunnellyChan Hyuk KangLena LörschJinmook LeeLucia KmecovaGizem SancerChrista BakerJenna JoroffSteven CalleYashvi PatelOlivia SatoJanice SalocotFarzaan SalmanSebastian Molina-ObandoMai BuiMatthew LichtenbergerEdmark TamboboyKatie MolloyAlexis Santana-CruzAnthony HernandezSeongbong YuMarissa SorekArzoo DiwanMonika PatelTravis AikenSarah MorejohnSanna KoskelaTansy YangDaniel LehmannJonas ChojetzkiSangeeta SisodiyaSelden KoolmanPhilip ShiuSky ChoAnnika BastBrian ReicherMarlon BlanquartLucy HoughtonHyungjun ChoiMaria IoannidouMatt CollieJoanna EckhardtBenjamin GorkoLi GuoZhihao ZhengAlisa PohMarina LinIstván TaiszWes MurfinÁlvaro Sanz DíezNils ReinhardPeter GibbNidhi PatelSandeep KumarMinsik YunMegan WangDevon JonesLucas Encarnacion-RiveraAnnalena OswaldAkanksha JadiaMert ErginkayaNik DrummondLeonie WalterIbrahim TastekinXin ZhongYuta MabuchiFernando Figueroa SantiagoUrja VermaNick ByrneEdda KunzeThomas CrahanRyan MargossianHaein KimIliyan GeorgievFabianna SzorenyiAtsuko AdachiBenjamin BargeronTomke StürnerDamian DemarestBurak GürAndrea BeckerRobert TurnbullAshley MorrenAndrea SandovalAnthony Moreno-SanchezDiego PachecoEleni SamaraHaley CrokeAlexander ThomsonConnor LaughlandSuchetana DuttaPaula Guiomar Alarcón de AntónBinglin HuangPatricia PujolsIsabel HaberAmanda González-SegarraAlbert LinDaniel ChoeVeronika LukyanovaNino ManciniZequan LiuTatsuo OkuboMiriam FlynnGianna VitelliMeghan LaturneyFeng LiShuo CaoCarolina Manyari-DiazHyunsoo YimAnh Duc LeKate MaierSeungyun YuYeonju NamDaniel BąbaAmanda AbusaifAudrey FrancisJesse GaykSommer HuntressRaquel BarajasMindy KimXinyue CuiAmy SterlingGabriella SterneAnna LiKeehyun ParkGeorgia DempseyAlan MathewJinseong KimTaewan KimGuan-Ting WuSerene DhawanMargarida BrotasCheng-Hao ZhangShanice BaileyAlexander del ToroKisuk LeeThomas MacrinaCasey Schneider-MizellSergiy PopovychOluwaseun OgedengbeRunzhe YangAkhilesh HalageriWill SilversmithStephan GerhardAndrew ChampionNils EcksteinDodam IhNico KemnitzManuel CastroZhen JiaJingpeng WuEric MitchellBarak NehoranShang MuJ. 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• Organismes : Institut de Biologie Valrose
• Publié dans Nature le 29/10/2020

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Résumé : Abstract The fruit fly Drosophila melanogaster has emerged as a key model organism in neuroscience, in large part due to the concentration of collaboratively generated molecular, genetic and digital resources available for it. Here we complement the approximately 140,000 neuron FlyWire whole-brain connectome 1 with a systematic and hierarchical annotation of neuronal classes, cell types and developmental units (hemilineages). Of 8,453 annotated cell types, 3,643 were previously proposed in the partial hemibrain connectome 2 , and 4,581 are new types, mostly from brain regions outside the hemibrain subvolume. Although nearly all hemibrain neurons could be matched morphologically in FlyWire, about one-third of cell types proposed for the hemibrain could not be reliably reidentified. We therefore propose a new definition of cell type as groups of cells that are each quantitatively more similar to cells in a different brain than to any other cell in the same brain, and we validate this definition through joint analysis of FlyWire and hemibrain connectomes. Further analysis defined simple heuristics for the reliability of connections between brains, revealed broad stereotypy and occasional variability in neuron count and connectivity, and provided evidence for functional homeostasis in the mushroom body through adjustments of the absolute amount of excitatory input while maintaining the excitation/inhibition ratio. Our work defines a consensus cell type atlas for the fly brain and provides both an intellectual framework and open-source toolchain for brain-scale comparative connectomics.

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