Pascal Fabre

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• Type de publi. :
• Date de publi. : 16/04/2023
• Auteurs : Mekan PiriyevLipin ChenHanh Le ViGabriel LogetSylvain TricotA. StrömbergTony RohelRozenn BernardLaurent PedesseauPascal TurbanPhilippe SchiefferBruno FabreYan Ting SunSebastian LourdudossYoan LégerNicolas BertruC. Cornet
• Organismes : Institut des Fonctions Optiques pour les Technologies de l'informatiON Institut des Fonctions Optiques pour les Technologies de l'informatiON Institut des Fonctions Optiques pour les Technologies de l'informatiON Institut des Sciences Chimiques de Rennes Institut de Physique de Rennes KTH Royal Institute of Technology [Kista] Institut des Fonctions Optiques pour les Technologies de l'informatiON Institut des Fonctions Optiques pour les Technologies de l'informatiON Institut des Fonctions Optiques pour les Technologies de l'informatiON Institut de Physique de Rennes Institut de Physique de Rennes Institut des Sciences Chimiques de Rennes KTH Royal Institute of Technology [Kista] KTH Royal Institute of Technology [Kista] Institut des Fonctions Optiques pour les Technologies de l'informatiON Institut des Fonctions Optiques pour les Technologies de l'informatiON Institut des Fonctions Optiques pour les Technologies de l'informatiON

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Source

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• Type de publi. : Article dans une revue
• Date de publi. : 01/04/2023
• Auteurs : Christiana KartsonakiJ Kenneth BaillieNoelia García BarrioJoaquín BaruchAbigail BeaneLucille BlumbergFernando BozzaTessa BroadleyAidan BurrellGail CarsonBarbara Wanjiru CitarellaAndrew DagensEmmanuelle DankwaChristl DonnellyJake DunningLoubna ElotmaniMartina EscherNataly FarshaitJean-Christophe GoffardBronner GonçalvesMatthew HallMadiha HashmiBenedict Sim Lim HengAntonia HoWaasila JassatMiguel Pedrera JiménezCedric LaouenanSamantha LissauerIgnacio Martin-LoechesFrance MentréLaura MersonBen MortonDaniel MunblitNikita NekliudovAlistair NicholBudha Charan Singh OinamDavid OngPrasan Kumar PandaMichele PetrovicMark PritchardNagarajan RamakrishnanGrazielle Viana RamosClaire RogerOana SandulescuMalcolm SemplePratima SharmaLouise SigfridEmily SomersAnca Streinu-CercelFabio TacconePavan Kumar VechamBharath Kumar Tirupakuzhi VijayaraghavanJia WeiEvert-Jan WilsXin Ci WongPeter HorbyAmanda RojekPiero OlliaroAli AbbasSheryl Ann AbdukahilNurul Najmee AbdulkadirRyuzo AbeLaurent AbelLara AbsilSubhash AcharyaAndrew AckerElisabeth AdamDiana AdriãoSaleh Al AgeelShakeel AhmedKate AinscoughEka AirlanggaTharwat AisaAli Ait HssainYounes Ait TamlihatTakako AkimotoErnita AkmalEman Al QasimRazi AlalqamAngela AlbertiTala Al-DabbousSenthilkumar AlegesanCynthia AlegreMarta AlessiBeatrice AlexKévin AlexandreAbdulrahman Al-FaresHuda AlfoudriImran AliAdam AliNaseem Ali ShahKazali Enagnon AlidjnouJeffrey AliudinQabas AlkhafajeeClotilde AllavenaNathalie AllouAneela AltafJoão AlvesRita AlvesJoão Melo AlvesMaria AmaralNur AmiraPhoebe AmpawRoberto AndiniClaire AndréjakAndrea AnghebenFrançois AngoulvantSéverine AnsartSivanesen AnthonidassMassimo AntonelliCarlos Alexandre Antunes de BritoArdiyan ApriyanaYaseen ArabiIrene AragaoFrancisco ArancibiaCarolline AraujoAntonio ArcadipanePatrick ArchambaultLukas ArenzJean-Benoît ArletChristel Arnold-DayLovkesh AroraRakesh AroraElise Artaud-MacariDiptesh AryalAngel AsensioMuhammad AshrafNamra AsifMohammad AsimJean Baptiste AssieAmirul AsyrafAnika 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RozeDesy RusmawatiningtyasClark RussellMaria RyanMaeve RyanSteffi RyckaertAleksander Rygh HoltenIsabela SabaSairah SadafMusharaf SadatValla SahraeiMaximilien Saint-GillesPranya SakiyalakNawal SalahuddinLeonardo SalazarJodat SaleemGabriele SalesStéphane SallaberryCharlotte Salmon GandonniereHélène SalvatorOlivier SanchezAngel Sanchez-MirallesVanessa Sancho-ShimizuGyan SandhuZulfiqar SandhuPierre-François SandrineMarlene SantosShirley Sarfo-MensahBruno Sarmento BanheiroIam Claire E SarmientoBenjamine SartonAnkana SatyaSree SatyapriyaRumaisah SatyawatiEgle SaviciuteParthena SavvidouYen Tsen SawJustin SchafferTjard SchermerArnaud ScherpereelMarion SchneiderStephan SchrollMichael SchwameisGary SchwartzBrendan SciclunaJanet ScottJames Scott-BrownNicholas SedillotTamara SeitzJaganathan SelvanayagamMageswari SelvarajooCaroline SemailleRasidah Bt SenianEric SennevilleClaudia SepulvedaFilipa SequeiraTânia SequeiraAry Serpa NetoPablo Serrano BalazoteEllen ShadowitzSyamin Asyraf ShahidanMohammad ShamsahAnuraj ShankarShaikh SharjeelCatherine ShawVictoria ShawAshraf SheharyarRohan ShettyRajesh Mohan ShettyHaixia ShiNisreen ShibanMohiuddin ShiekhNobuaki ShimeHiroaki ShimizuKeiki ShimizuSally ShrapnelPramesh Sundar ShresthaShubha Kalyan ShresthaHoi Ping ShumNassima Si MohammedNg Yong SiangJeanne SibiudeAtif SiddiquiPiret SillaotsCatarina SilvaRogério SilvaMaria Joao SilvaWai Ching SinDario SinattiPunam SinghBudha Charan SinghPompini Agustina SitompulKarisha SivamVegard SkogenSue SmithBenjamin SmoodCoilin SmythMichelle SmythMichelle SmythMorgane SnackenDominic SoTze Vee SohJoshua SolomonTom SolomonAgnès SommetRima SongTae SongJack Song ChiaMichael SonntagbauerAzlan Mat SoomAlberto SottoEdouard SoumMarta SousaAna Chora SousaMaria Sousa UvaVicente Souza-DantasAlexandra SperryElisabetta SpinuzzaB DarshanaShiranee SriskandanSarah StablerThomas StaudingerStephanie-Susanne StecherTrude SteinsvikYmkje StienstraBirgitte StiksrudEva StolzAmy StoneAdrian Streinu-CercelDavid StuartAmi StuartDecy SubektiGabriel SuenJacky SuenAsfia SultanaCharlotte SummersDubravka SupicDeepashankari SuppiahMagdalena SurovcováSuwarti SuwartiAndrey SvistunovSarah SyahrinKonstantinos SyrigosJaques SztajnbokKonstanty SzuldrzynskiShirin TabriziLysa TaghersetShahdattul Mawarni TaibEwa TalarekSara TalebJelmer TalsmaRenaud TamisierMaria Lawrensia TampubolonKim Keat TanYan Chyi TanTaku TanakaHiroyuki TanakaHayato TaniguchiHuda TaqdeesArshad TaqiCoralie TardivonPierre TattevinM Azhari TaufikHassan TawfikRichard TedderTze Yuan TeeJoão TeixeiraSofia TejadaMarie-Capucine TellierSze Kye TeohVanessa TeotonioFrançois TéouléPleun TerpstraOlivier TerrierNicolas TerziHubert Tessier-GrenierAdrian TeyAlif Adlan Mohd ThabitAnand ThakurZhang Duan ThamSuvintheran ThangaveluVincent ThibaultSimon-Djamel ThibervilleBenoît ThillJananee ThirumanickamShaun ThompsonEmma ThomsonDavid ThomsonSurain Raaj Thanga ThuraiRyan ThwaitesPaul TierneyVadim TieroshynPeter TimashevJean-François TimsitNoémie TissotJordan Zhien Yang TohMaria TokiKristian TonbySia Loong TonniiMargarida TorresAntoni TorresRosario Maria Torres Santos-OlmoHernando Torres-ZevallosMichael TowersTony TrapaniThéo TreouxCécile TromeurIoannis TrontzasTiffany TrouillonJeanne TruongChristelle TualSarah TubianaHelen TuiteJean-Marie TurmelLance TurtleAnders TveitaPawel TwardowskiMakoto UchiyamaP UdayangaAndrew UdyRoman UllrichAlberto UribeAsad UsmanTimothy UyekiCristinava VajdovicsPiero ValentiniLuís Val-FloresAmélie ValranStijn van de VeldeMarcel van den BergeMachteld van der FeltzJob van der PalenPaul van der ValkNicky van der VekensPeter van der VoortSylvie van der WerfLaura van GulikJarne van HattemCarolien van NettenFrank van Someren GreveIlonka van VeenHugo van WilligenNoémie VanelHenk VanoverscheldePooja VargheseMichael VarroneShoban Raj VasudayanCharline VauchyShaminee VeeranAurélie VeislingerSebastian VenckenSara VenturaAnnelies VerbonJames VickersJosé Ernesto VidalCésar VieiraDeepak VijayanJoy Ann VillanuevaJudit VillarPierre-Marc VilleneuveAndrea VilloldoGayatri VishwanathanBenoit VisseauxHannah VisserChiara VitielloHarald VonkemanFanny VuottoSuhaila Abdul WahabNoor Hidayu WahabNadirah Abdul WahidMarina WainsteinWan Fadzlina Wan Muhd ShukeriChih-Hsien WangSteve WebbKatharina WeilTan Pei WenSanne WesseliusT Eoin WestMurray WhamBryan WhelanNicole WhitePaul Henri WickyAurélie WiedemannSurya Otto WijayaKeith WilleSuzette WillemsVirginie WilliamsCalvin WongYew Sing WongTeck Fung WongNatalie WrightGan Ee XianLim Saio XianKuan Pei XuanIoannis XynogalasSiti Rohani Binti Mohd YakopMasaki YamazakiYazdan YazdanpanahNicholas Yee Liang HingCécile YelnikChian Hui YeohStephanie YerkovichToshiki YokoyamaHodane YonisObada YousifSaptadi YuliartoAkram ZaaqoqMarion ZabbeKai ZacharowskiMasliza ZahidMaram ZahranNor Zaila Binti ZaidanMaria ZambonMiguel ZambranoAlberto ZanellaKonrad ZawadkaNurul ZaynahHiba ZayyadAlexander ZoufalyDavid Zucman
• Organismes : University of Oxford Infection, Anti-microbiens, Modélisation, Evolution University of Oxford University of Oxford Agents infectieux, résistance et chimiothérapie - UR UPJV 4294 Agents infectieux, résistance et chimiothérapie - UR UPJV 4294 Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Ponchaillou] ARN régulateurs bactériens et médecine
• Publié dans International Journal of Epidemiology le 30/10/2020

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Résumé : Background: We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory and emerging Infection Consortium (ISARIC) COVID-19 cohort, one of the world's largest international, standardized data sets concerning hospitalized patients.Methods: The data set analysed includes COVID-19 patients hospitalized between January 2020 and January 2022 in 52 countries. We investigated how symptoms on admission, co-morbidities, risk factors and treatments varied by age, sex and other characteristics. We used Cox regression models to investigate associations between demographics, symptoms, co-morbidities and other factors with risk of death, admission to an intensive care unit (ICU) and invasive mechanical ventilation (IMV).Results: Data were available for 689 572 patients with laboratory-confirmed (91.1%) or clinically diagnosed (8.9%) SARS-CoV-2 infection from 52 countries. Age [adjusted hazard ratio per 10 years 1.49 (95% CI 1.48, 1.49)] and male sex [1.23 (1.21, 1.24)] were associated with a higher risk of death. Rates of admission to an ICU and use of IMV increased with age up to age 60 years then dropped. Symptoms, co-morbidities and treatments varied by age and had varied associations with clinical outcomes. The case-fatality ratio varied by country partly due to differences in the clinical characteristics of recruited patients and was on average 21.5%.Conclusions: Age was the strongest determinant of risk of death, with a ∼30-fold difference between the oldest and youngest groups; each of the co-morbidities included was associated with up to an almost 2-fold increase in risk. Smoking and obesity were also associated with a higher risk of death. The size of our international database and the standardized data collection method make this study a comprehensive international description of COVID-19 clinical features. Our findings may inform strategies that involve prioritization of patients hospitalized with COVID-19 who have a higher risk of death.

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Fichiers liés : dyad012.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/04/2023
• Auteurs : Jean-Francois HamelJean JorisKarem SlimJean-Marc RégimbeauEddy CotteMaxime LégerAurélien VenaraNora Abbes OrabiElodie AgutPascal AlfonsiAsma AliliJibba AmraouiAdeline AndreJean-Marc ArimonLaurent ArnalsteenRobert AsztalosCyril AudouyOphélie AumontSylvain AuvrayHubert BaiettoGregorio BalboMaryse Barreau AguileraNathan BeaupelNathan BeaupelZeineb Ben LazregSophie Beguinot-HoltzschererJean-Paul BellerArnauld BellouardImed Ben HendaMohamed BentamenePierre BernardNicolas BerthonAmélie BiblocqueThomas BievreMarco BilosiBenjamin BlancAdrien BlattDamien BlehautAnne BockJean-Pierre BongiovanniMarc BonnetNoredinne BouarroudjDavid BoissierHenry BoretRuddy BorgZoheir BouchairFrancois BouchardMohamed BoumadaniDavid BounicaudOlivier BourdeixJ. BourseauGuillaume BozioDorothée BrachetAmine BrekNicolas BriezCarole Buisset-SubiranBrigitte CalvetAnna Cartaux-TaiebMarie CastiglioniMaryline CatinoisMael Chalret Du RieuClaire ChalumeauGerald ChambrierReza ChamlouNathalie ChapelPierre ChenetPierre ChiracSeddik ChokkairiXavier ChopinNiki ChristouEtienne ChuffartFrançois CorfiottiCarmen CrausEmmanuel CuellarGilles DardenneNicola de AngelisUgo de IoroFabien DechanetRachel DellisLaurence DemaslesChristine DenetBenjamin DerooVéronique Desfourneaux-DenisSylvain DileonRichard DouardCarlos DoradoEva DorscheidFrédéric DumontFrançois DurameEmilie DuchalaisAurélien DupreSophie DufraisseMohamed Amine ElghaliEmmeric HutinAloui EmnaEric EssomeNathalie FabreVirginie FaivreJean-Luc FaucheronPatrick FavouletPhilippe FernouOlivier FirtionRenaud FlameinSabina FloreaChristophe de la FontaineDamien ForestierErwann FournDacian Vasile FrentiuRomain FrisoniAlain FrisoniThomas GautierFlorent GentySebastian GeorgeanuAdeline GermainStéphanie GibertBruno GilbertBenoit GignouxNicolas GoasguenPierre GoubaultPhilippe GresJérémie GuedjBruno GuignardJean GugenheimCaroline GuaquiereJean Luc GuiotDavid GuinierKamel HailCaroline HatwelElean IatanThérèse JaneckiThomas JanyJérôme JaspartFrédéric JourneLionel JouffretAicha KassoulFehmi KattouPhilipe KellerThomas KnepflerTarik KhouriKonstantinos KothonidisPierre LandreauGuillaume LangloisGerald Le BartzSébastien LebasDaniel LeonardDavid LeonardJulien LeporrierGuy LescureRomain LewandowskiAntonella LiddoJean-Hugues LongevilleIoan LucescuAntoine MarianiPascale MarianiGwenaelle MartinOlivier MartinetDamien MassalouJean-Loup MassardFrançois MauvaisDavide MazzaJean Mbuyamba KatapileFabrice MilouFrantz MirreCaroline Mor MartinezAlexandre MensierClaude MerguiJean-Philippe MestralletCaroline MeyerNicolas MocellinSerge MontagneOmar NaseefMarion OrvilleSandrine Ostermann-BucherMehdi OuaissiXavier PaqueronCyrielle PaquetLaurent PasseboisVirginie Pichot-DelahayeMarc PilletJean Charles PottieLaurent PlardFleur PlumereauJames PoincenotMarie PoisblancBenoit PoupardJan Martin ProskePierre PucheOlivier RaspadoRomain RiboudBarivola RakotoarisoaKevin RaynaudThierry RazafindratsiraMyriam RenaudDidier RioDidier RioJeremie RipocheBenjamin RousselMarc Saint DenisPascale SalaunPierre Yves SageMarie-Lorraine ScherrerFranck SirisierBoudewijn SmeetsMilan SmejkalJean-Philippe SteinmetzMarion TavernierRemy ThievenazMihaela TircaLaurence ToqueElhocine TrikiDimitri TzanisBernard VacherSerge VanwymeerschEstelle VauclairRomain VerhaegheVictoria VetrilaChristine VieuilleFrançois VermeulenJean-Charles VignalChristian VoilinPierre de WailliAlbert WolthuisSophie Zaepfel
• Organismes : Centre de recherche clinique CHU Clermont-Ferrand Chirurgie digestive [CHU Amiens] Simplification des soins chez les patients complexes - UR UPJV 7518 Centre Hospitalier Lyon Sud [CHU - HCL] MethodS in Patients-centered outcomes and HEalth ResEarch Medical Intensive Care, Angers University Hospital, Nantes, France Centre Hospitalier Universitaire d'Angers The Enteric Nervous System in gut and brain disorders [U1235] Hôpital Saint-Joseph [Marseille] CRLCC Val d'Aurelle - Paul Lamarque Service de chirurgie générale et viscérale
• Publié dans Journal of Gastrointestinal Surgery le 01/11/2020

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• Type de publi. : Autre publication
• Date de publi. : 21/03/2023
• Auteurs : Amandine BellecPascal MartinNeus VilàStéphane LenfantStéphane CampidelliY. J. DappeDenis FrathMaria Luisa Della RoccaBruno FabreSaioa Cobo
• Organismes : Laboratoire Matériaux et Phénomènes Quantiques Interfaces, Traitements, Organisation et Dynamique des Systèmes Université de Lorraine Nanostructures, nanoComponents & Molecules - IEMN Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520 Laboratoire Innovation en Chimie des Surfaces et NanoSciences Nanosciences et Innovation pour les Matériaux, la Biomédecine et l'Energie (ex SIS2M) Service de physique de l'état condensé Groupe Modélisation et Théorie Laboratoire de Chimie - UMR5182 Laboratoire Matériaux et Phénomènes Quantiques Institut des Sciences Chimiques de Rennes Laboratoire de chimie de coordination

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Résumé : Sommaire : – Détection électrique de la transition de spin de molécules Amandine Bellec – Electroluminescence de molécules chargées adsorbées sur une surface métallique Amandine Bellec – Approche moléculaire pour la fabrication de surfaces fonctionnalisées de Qubits moléculaires Pascal Martin – Electropolymérisation itérative contrôlée Neus Vila – Formation et dissociation induites par STM des liaisons au sein d’une molécule Stéphane Lenfant – Synthèse de nanographène sur surface semi-conductrice Stéphane Campidelli – Véritable isolant topologique moléculaire ou simple fil moléculaire conducteur ? Yannick Dappe – Transfert de l’effet d’interférence quantique moléculaire à différentes échelles de longueur Maria Luisa Della Rocca – Commutateurs moléculaires dynamiques avec conductance différentielle négative hystérétique Denis Frath – Transport de charge intermoléculaire dans des assemblages supramoléculaires Denis Frath – Un nouveau moteur moléculaire électrique Bruno Fabre – Synergie entre propriétés électroniques et magnétiques dans un complexe de manganèse Saioa Cobo

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Fichiers liés : Chronique NEMO #1.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 06/03/2023
• Auteurs : Lise CuzinPhilippe FlandreClotilde AllavenaRomain PalichClaudine DuvivierAgathe BeckerHélène LarochePascal PuglieseAndré CabieCatherine ChirouzeO BabreK BouillerF BozonA BrunelE ChevalierL Hustache-MathieuJ LagoutteQ LepillerS Marty-QuinternetP MuretB RosolenN TissotS JaffuelC JacometC AumeranO BaudA BrebionV CorbinE GoncalvezC HenquellH LaurichesseO LesensD MazzocolinA MirandN MrozekC TheisM VidalI LamauryF BissuelF BoulardE CurlierI FabreE HalleyC Herrmann-StorckC Le GuillouS MarkowiczM MarquetR OuissaM ReceveurJ ReltienP RogerB TressieresD MerrienO BollangierD BoucherT GuimardL LaineS LeautezM MorrierP PerréP PointJ FaucherA CypierreS Ducroix-RoubertouH DuroxC Genet-VillegerJ PascualP PinetS RogezJ WoillardL CotteF AderD AlfaiateAgathe BeckerA BoibieuxC BrochierF Brunel-DalmasO CannessonP ChiarelloC ChidiacA ConradS DegroodtT FerryM GodinotV IcardJ LivrozetD MakhloufiT PerpointM PerryC PouderouxS RouxM TrabaudC Triffault-FillitF ValourI RavauxA MénardS AherfiS AmraneA BelkhirP ColsonC DhiverM Martin-DegioanniL MeddebM MokhtariA MotteH Tissot-DupontC ToméiI Poizot-MartinS BrégigeonM DucassouS GalieA IvanovaI JaquetHélène LarocheV Obry-RoguetM OrticoniE RessiotA RitlengT Rojas-RojasO Zaegel-FaucherAndré CabieS AbelJ BavayB BigeardO CabrasLise CuzinR Dupin de MajoubertL FagourK GuitteaudM LehouxC MontagnacS Pierre-FrançoisK RomeJ TurmelJ ReynesN AtouiM BistoquetE DelaporteV Le MoingJ LejeuneA MakinsonN MeftahC Merle de BoeverB MontesA Montoya FerrerE TuaillonB LefèvreM AndréG BaronnetS BevilacquaL BoyerM BouillonA CharmillonM DelestanE FrentiuF GoehringerS HénardE JeanmaireC RabaudA Radjabaly-MandjeeF RaffiClotilde AllavenaE André-GarnierA Asquier-KhatiE BillaudC BironB BonnetS BouchezD BoutoilleC Brunet-CartierM CavellecC DeschanvresV FerréB GaboritA GrégoireM GrégoireT JovelinM LefebvreR LecomteR MahotP MorineauE ParedesV ReliquetE André-GarnierS SécherA SoriaPascal PuglieseS BréaudM BuscotM CarlesD ChirioE CuaP DellamonicaE DemonchyA de MonteJ DurantS FerrandoR GarraffoC MichelangeliA NaqviI PerbostC PradierB Prouvost-KellerK RissoI TouitouA ViotS Wehrlen-PuglieseL HocquelouxC GubavuV LegrosF PeiraT PrazuckV RzepeckiA SèveA CheretA Barrail-TranA CastroR ColarinoC GoujardS JaureguiberryY QuertainmontE TeicherV JolyC CharpentierD DescampsM DigumberA GervaisJ GhosnZ JuliaR LandmanS LarivenS Le GacF LouniG PeytavinC RiouxY YazdanpanahClaudine DuvivierK AmazzoughG BenabdelmoumenP BossiG CessotC CharlierP ConsignyE Gomes-PiresK JidarE LafontF LanternierO LortholaryC LouisinJ LourencoC MelenotteP ParizeA PouvaretC RouzaudA SerrisF TouamC KatlamaR AgherC BlancY DudoitN HamaniN QatibI QzaibriL LenclumeRomain PalichL SchneiderS SeangR TubianaM ValantinF Bani-SadrM BermejoJ BergerS DemotierM HentzienG JulienI KmiecD LambertH MartyY N’guyenJ RomaruC ArvieuxM BaldeyrouF BenezitJ ChapplainM DupontJ DuthéT JovelinA LebotF LemaitreA MaillardC MorlatS Patrat-DelonM Poisson-VannierC PronierM RevestJ SinteffF SoualaP TattevinA Gagneux-BrunonElisabeth Botelho-NeversA FrésardF LuchtV RonatD ReyC CheneauC Bernard-HenryE de MautortSamira Fafi-KremerP FischerP GantnerC MélounouM PartisaniP DelobelM AlvarezN BiezunskiA DebardC DelpierreC GarnierG GaubeL LelièvreM MarcelG Martin-BlondelM PiffautL PorteK SauneO RobineauE AïssiF AjanaI AlcarazE AlidjinouV BacletL BocketA BoucherV DerdourM GilbertT HuleuxB Lafon-DesmursA MeybeckM PradierM TetartP ThillM ValetteN VigetG Corvaisier
• Organismes : Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections
• Publié dans Journal of Antimicrobial Chemotherapy le 31/10/2020

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Résumé : Abstract Objectives To analyse the occurrence of virological failure (VF) in patients starting ART with an integrase strand transfer inhibitor (INSTI)-based regimen in recent years, in relation with previous episodes of low-level viral load (LLVL). Patients and methods Patients starting a first ART between 1 January 2015 and 31 December 2020 based on two NRTIs and one INSTI were included if after virological control (two measures of VL < 50 copies/mL) they had a minimum of two additional VL measurements. Cox models adjusted for sex, age, acquisition group, hepatitis B or C coinfection, place of birth, year of ART initiation, CD4+ T cells and VL at ART initiation, duration of known HIV infection and of ART regimen were used to assess the association between the time to VF and the occurrence of LLVL. ART regimen was evaluated as time-varying covariate. Results LLVL was described in 13.7% and VF in 11% of the 3302 patients. LLVL was associated with VF [adjusted HR (aHR) 1.76, 95% CI 1.28–2.41], as well as age (aHR 0.97/year, 95% CI 0.96–0.98), CD4+ T cell count at ART initiation (aHR 0.93, 95% CI 0.87–0.98), heterosexual transmission (aHR 1.76, 95% CI 1.30–2.37) and being born abroad (aHR 1.50, 95% CI 1.17–1.93). Conclusions LLVL was related to VF. Even in the absence of subsequent failure, LLV episodes have a cost. Thus any VL value above 50 copies/mL should lead to enhanced adherence counselling.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Boris SorinMichele IudiciMary-Jane GuerryMaxime SamsonPhilip BielefeldThibault MailletMathilde NouvierAlexandre KarrasLara MeyerChristian LavigneAlexis RégentCécile-Audrey DurelMarc FabrePierre CharlesQuentin RaimbourgAurélia LanteriGrégory PugnetFrédéric RivièreMarc Pineton De ChambrunPatrice CacoubGuillaume Le GuennoPierre JourdainArsène MékinianRomain PauleJérémie DionPaul LegendrePascal CohenLoïc GuillevinXavier PuéchalBenjamin Terrier
• Organismes : Immunologie - Immunopathologie - Immunothérapie [CHU Pitié Salpêtrière]
• Publié dans Rheumatology (Oxford, England) le 24/03/2022

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Boris SorinMichele IudiciMary-Jane GuerryMaxime SamsonPhilip BielefeldThibault MailletMathilde NouvierAlexandre KarrasLara MeyerChristian LavigneAlexis RégentCécile-Audrey DurelMarc FabrePierre CharlesQuentin RaimbourgAurélia LanteriGrégory PugnetFrédéric RivièreMarc Pineton De ChambrunPatrice CacoubGuillaume Le GuennoPierre JourdainArsène MékinianRomain PauleJérémie DionPaul LegendrePascal CohenLoïc GuillevinXavier PuéchalBenjamin Terrier
• Organismes : Immunologie - Immunopathologie - Immunothérapie [CHU Pitié Salpêtrière]
• Publié dans Rheumatology (Oxford, England) le 24/03/2022

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Boris SorinMichele IudiciMary-Jane GuerryMaxime SamsonPhilip BielefeldThibault MailletMathilde NouvierAlexandre KarrasLara MeyerChristian LavigneAlexis RégentCécile-Audrey DurelMarc FabrePierre CharlesQuentin RaimbourgAurélia LanteriGrégory PugnetFrédéric RivièreMarc Pineton De ChambrunPatrice CacoubGuillaume Le GuennoPierre JourdainArsène MékinianRomain PauleJérémie DionPaul LegendrePascal CohenLoïc GuillevinXavier PuéchalBenjamin Terrier
• Organismes : Immunologie - Immunopathologie - Immunothérapie [CHU Pitié Salpêtrière]
• Publié dans Rheumatology (Oxford, England) le 24/03/2022

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• Type de publi. : Rapport
• Date de publi. : 16/12/2022
• Auteurs : Florence GuillotAdeline BéaPascal Robert-Cols
• Organismes : Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés CAUE 81 ACCA

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Fichiers liés : Cordes(81)-Ormeaux 2022 prefigur 2023.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/12/2022
• Auteurs : Andi Nur CahyoRudi Hari MurtiEka T.S. PutraFetrina OktaviaSigit IsmawantoPierre MournetDenis FabrePascal Montoro
• Organismes : Indonesian Rubber Research Institute Universitas Gadjah Mada Universitas Gadjah Mada Universitas Gadjah Mada Indonesian Rubber Research Institute Indonesian Rubber Research Institute Amélioration génétique et adaptation des plantes méditerranéennes et tropicales Département Systèmes Biologiques Amélioration génétique et adaptation des plantes méditerranéennes et tropicales Département Systèmes Biologiques Amélioration génétique et adaptation des plantes méditerranéennes et tropicales Département Systèmes Biologiques
• Publié dans Industrial Crops and Products le 27/10/2020

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Résumé : Climate change has an impact. Droughts will become more common in the future and as a result is the drop of rubber production. Drought tolerant rubber genotypes, may reduce drought risk, could be discovered by selection of germplasm and crossing progenies. As perennial plant, conventional rubber selection of rubber needs long time. Molecular detection such as QTL (precise and fast detection) for screening to get drought tolerant rubber genotypes is very important to be conducted. A variable widely used to screen stress tolerance genotypes is Performance Index (PI). Measurement of PI in normal, moderate, and severe drought stress enables the calculation of the Drought Factor Index (DFI). DFI as an integrative parameter for drought tolerance trait provides simple and robust method to quantify the tolerance ability of plants to withstand drought condition. This research is the first application of DFI to select drought-tolerant rubber genotypes and to identify QTLs related to DFI. This research aimed to select candidate drought-tolerant genotypes from the biparental population PB 260 x SP 217 as well as to identify QTLs related to DFI variable. One hundred and thirty-two genotypes and four control commercial clones, namely PB 260, SP 217, GT1, and RRIM 600 have been successfully screened using DFI variable. Normal, moderate, and severe drought stresses were calibrated for each plant by monitoring the fraction of transpirable soil water (FTSW). Due to the skewed distribution of DFI data that was generated in the phenotyping step, the Kruskal-Wallis non-parametric test was used to test the significance of each QTLs using MapQTL version 6 software. From this research, it can be concluded that DFI can be used as a parameter for selection of drought tolerant rubber clones. Based on DFI calculation, the top ten high DFI genotypes/clones were genotype number 34, 206, 056, 007, 205, 225, 066, 235, 109, and clone RRIM 600. Furthermore, the most significant detection of QTL for DFI variables was found in locus g5TA2155, located at 0.553 cM in LG5. It indicated that this locus contained genes controlling DFI trait.

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