Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/02/2026
• Auteurs : Anthony L’hostellierCharles KouanfackCorine ChazallonSandra Wagner-CardosoSerge Paul EholieNeiva BanzeGuttiga HalueJacqueline CapeauConstance DelaugerreRaoul MohFabrice BonnetLiliane Mfeukeu KuateAntoine JaquetHugo PerazzoCharlotte BernardJean-Philippe BastardLauriane GoldwirtPaul VilquinPedroso Pedro NhassengoMargot LavaléeNicolas MinvielleP J DoddOlivier MarcyJean-Michel MolinaBeatriz GrinsztejnPierre O Sellier
• Organismes : Bordeaux population health Global Health in the Global South Université de Dschang [Cameroun] = University of Dschang [Cameroon] Bordeaux population health Global Health in the Global South Fundação Oswaldo Cruz / Oswaldo Cruz Foundation Centre Hospitalier Universitaire de Treichville [Abidjan, Côte d'Ivoire] Instituto Nacional de Saude [Maputo, Mozambique] University of Phayao Centre de Recherche Saint-Antoine Assistance publique - Hôpitaux de Paris (AP-HP) Programme PAC-CI Bordeaux population health Global Health in the Global South Hôpital Saint-André [Bordeaux] Université de Yaoundé I Bordeaux population health Global Health in the Global South Fundação Oswaldo Cruz / Oswaldo Cruz Foundation Bordeaux population health Global Health in the Global South Assistance publique - Hôpitaux de Paris (AP-HP) Institut Mondor de Recherche Biomédicale Hopital Saint-Louis [AP-HP] Université Paris Cité Hopital Saint-Louis [AP-HP] Université Paris Cité Instituto Nacional de Saude [Maputo, Mozambique] Agence Nationale de Recherches sur le Sida et les Hépatites Virales Agence Nationale de Recherches sur le Sida et les Hépatites Virales University of Sheffield [Sheffield] Bordeaux population health Global Health in the Global South Hopital Saint-Louis [AP-HP] Hôpital Lariboisière-Fernand-Widal [APHP] Université Paris Cité Fundação Oswaldo Cruz / Oswaldo Cruz Foundation Hopital Saint-Louis [AP-HP] Hôpital Lariboisière-Fernand-Widal [APHP] Université Paris Cité
• Publié dans BMJ Open le 26/10/2020

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Résumé : Introduction: Increasing evidence suggests that dolutegravir (DTG), endorsed by the WHO since 2018 for first-line antiretroviral therapy (ART), is associated with significant weight gain and potentially also with cardiometabolic disorders. In an effort to expand therapeutic options for people living with HIV (PLHIV), the EvaLuating the non-inferiority of DORAvirine vs DOlutegravir trial aims to compare the virologic efficacy of doravirine (DOR) and DTG-based regimens and to assess their safety, including a focus on cardiometabolic effects. Methods and analysis: This is an international, phase III, multicentre, open-label, non-inferiority, randomised trial that will enrol 610 ART-naïve PLHIV (HIV RNA≥1000 copies/mL at screening) across six countries (Brazil, Cameroon, France, Côte d'Ivoire, Mozambique and Thailand) spanning four continents. Key inclusion criteria include age ≥18 years, confirmed HIV-1 infection with plasma RNA levels ≥1000 copies/mL, indication for ART initiation and no prior ART exposure. Participants will be randomised in a 1:1 ratio to receive either DOR 100 mg once daily in combination with tenofovir disoproxil fumarate (TDF) (300 mg daily) plus lamivudine (3TC) (300 mg daily) or DTG (50 mg daily) in combination with TDF (300 mg once daily) plus either emtricitabine (FTC) (200 mg daily) or 3TC (300 mg daily). Randomisation will be stratified by screening HIV-1 RNA load (≤100 000 or >100 000 copies/mL) and by country. The primary outcome is virological efficacy, defined as the proportion of participants achieving HIV-1 RNA <50 copies/mL at week 48 on the assigned treatment (FDA Snapshot algorithm). Secondary outcomes include cardiometabolic safety endpoints (ie, weight gain, insulin resistance, hypertension, diabetes, waist and hip circumferences, waist-to-hip ratio, fasting glycaemia, insulin and fasting serum lipids), along with mental health, quality of life, virological and immunological parameters. Final data collection is expected by July 2028. Ethics and dissemination: Primary outcome results (week 48) are expected in early 2028. The project was submitted to and approved by national ethics committees and pharmaceutical regulatory authorities in all participating countries: Brazil (CEP INI FIOCRUZ (21.040-900)/CEP HGNI (26.030-380)); Cameroon (CNERSH (2024/09/1717/CE/CNERSH/SP)/Ministry of Public Health (D30-1464/AAR/MINSANTE/SG/DROS/CRC); Côte d'Ivoire: (CNESVS (0018224/MSHPCMU/CNESVS-km)/AIRP (1329/AIRP/DISMP/Om/kbaag); France (CTIS CPP/ANSM (2023-508626-10-00)); Mozambique (CNBS (20/CNBS/25)/ANARME (4635/380/ANARME)); Thailand: (IHRP (08/1944)/Thai FDA: ongoing on 19 January 2026). The trial received authorisation from the French National Commission for Data Protection and Liberties (CNIL) under approval number 924 302. Written informed consent is obtained from all participants prior to any study-specific procedures and trial enrolment, in accordance with the Declaration of Helsinki and applicable national regulations. Study findings will be disseminated through publication in peer-reviewed journals and presentations at national and international scientific conferences. Results will also be communicated to policymakers, healthcare professionals, community stakeholders and study participants through appropriate dissemination activities, including policy briefs, stakeholder meetings and lay summaries on dedicated and easily accessible platforms.

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Fichiers liés : bmjopen-16-2.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/02/2026
• Auteurs : Boris BarrovecchioGwenhael ColinLaurent ArgaudIsabelle DesmeullesPierre BaillyNicholas SedillotHelene NougueNicolas PichonShidasp SiamiGaetan PlantefeveGuillaume SchnellMaleka SchenckPierrick CronierSebastien PerbetAnais CurtiaudMichael PiagnerelliMehran MonchiNicolas DeyeJuliette AudibertCharles CerfPhilippe AriesGuillaume ThieryVincent DasS. SilvaMarc SimonGwenaelle JacqFrederic JacobsCedric DaubinVirginie LemialePascal BeuretGuillaume Gele-DecaudinJean-Pierre QuenotJean-Baptiste LascarrouOlivier LesieurChristophe GuittonStephane Legriel
• Organismes : Research on Healthcare Performance Centre Hospitalier Universitaire de Toulouse Toulouse NeuroImaging Center Institut National de la Santé et de la Recherche Médicale Université de Toulouse
• Publié dans Resuscitation le 28/10/2020

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Résumé : Brain death after hanging-induced cardiac arrest is a fatal complication about which few data are available. We aimed at identifying the early predictors of progression to brain death in patients with hanging-induced cardiac arrest.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/02/2026
• Auteurs : Loren MorgilloLèna BrionneXavier FalourdJérôme AdrienBérangère LesaintVictor TrillaudThibaut ColinartPierre OuagnePhilippe SteyerMarwa AbidaJohnny BeaugrandAlain Bourmaud
• Organismes : Institut de Recherche Dupuy de Lôme Unité de recherche sur les Biopolymères, Interactions Assemblages BIBS - Plateforme Bioressources : Imagerie, Biochimie & Structure Matériaux, ingénierie et science [Villeurbanne] Consortium Lyon Saint-Etienne de Microscopie Institut de Recherche Dupuy de Lôme Université de Bretagne Sud Institut de Recherche Dupuy de Lôme Institut de Recherche Dupuy de Lôme
• Publié dans Industrial Crops and Products le 27/10/2020

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Résumé : Flax fibres are increasingly explored as sustainable reinforcements in high-performance composites due to their remarkable stiffness and strength. However, their hygroscopic nature and complex hierarchical organisation pose challenges for dimensional stability and long-term durability. Among the intrinsic microstructural heterogeneities, kink-bands, localised deformations associated with cellulose misalignment and increased porosity, may affect water uptake and swelling. Despite their potential impact, the effect of kink-bands on water sorption and moisture-induced structural changes has not been directly investigated. This study investigates the influence of kink-band density on the hygroscopic behaviour of flax fibres using an integrated multi-scale approach combining Dynamic Vapour Sorption (DVS), Environmental Scanning Electron Microscopy (ESEM), X-ray microtomography, and solid-state Nuclear Magnetic Resonance (ss-NMR). Three flax fibre batches with distinct kink-band frequencies were prepared through controlled mechanical processing. DVS results revealed no significant difference in overall water sorption capacity between batches, indicating that kink-bands do not markedly affect global hygroscopicity. However, ESEM and X-ray tomography analyses highlighted heterogeneous swelling behaviour at the bundle and fibre scales, with kink-band regions exhibiting lower expansion than intact zones, suggesting a compensating effect of internal pores on local deformation. Solid-state NMR analyses revealed that, although fibril dimensions and overall crystallinity were unchanged, fibres with higher kink-band content exhibited increased water accessibility and subtle nanoscale polymer reorganisation. This suggests that kink-bands promote local water penetration and interactions with surrounding non-cellulosic components, without altering overall bulk hygroscopicity. Together, these results indicate that kink-bands modulate local moisture dynamics, providing new insights into the structural–functional relationships governing flax fibre behaviour in humid environments. They are also relevant for natural fibre composites, as understanding how kink-bands influence local moisture dynamics can inform predictions of dimensional stability, fibre–matrix interactions, and long-term durability.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/02/2026
• Auteurs : Claire Penetrat-RogerJulie LourtetChristophe AvelineNathalie BernardMichel CarlesAxel Maurice SzamburskiEmmanuel NovyMaya EnserTiphaine VandenberghePierre-Sylvain MarcheixJean-David WerthelGeoffroy NourrissatCécile BataillerPhilippe BoisrenoultSimon MarmorBertrand BoyerChristian DumontierPhilippe TchenioJean-Roger WertherBenoit PedeutourFlorence AimCécile ToanenLouis RonyMatthieu LalevéeThierry FavierStéphane MaugerChristophe Le DuValérie DumaineJérôme DelambreMarie FaruchMarc GarnierJean-Noël EvainChristophe HuetFranck Remy
• Organismes : Centre Hospitalier Universitaire de Nîmes Caractéristiques féminines des dysfonctions des interfaces cardio-vasculaires Hôpital Joseph Ducuing - Varsovie [Toulouse] Hopital Privé Sévigné [Cesson-Sévigné, France] Hôpital Lapeyronie [CHU Montpellier] Centre Hospitalier Universitaire de Nice Hôpital Pasteur [Nice] Stress, Immunité, Pathogènes The University of Queensland Hôpital Cochin [AP-HP] CHU Gabriel Montpied [Clermont-Ferrand] CHU Limoges Hôpital Ambroise Paré [AP-HP] Centre de Recherche Saint-Antoine Hôpital de la Croix-Rousse [CHU - HCL] Centre Hospitalier de Versailles André Mignot Groupe Hospitalier Diaconesses Croix Saint-Simon Santé Ingénierie Biologie Saint-Etienne Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] Centre de la Main [Baie-Mahault, Guadeloupe] Centre de la main [Toulon] CHU Saint-Antoine [AP-HP] Centre de la main du Pays d’Aix - SOS MAIN [Aix-en-Provence] Groupe Hospitalier Diaconesses Croix Saint-Simon Polyclinique Bordeaux Nord Aquitaine Centre Hospitalier Universitaire d'Angers CHU Rouen Clinique Toutes Aures Centre Hospitalier de Soissons Clinique de l’Alliance - Saint-Cyr-sur-Loire (FRANCE) Hôpital Cochin [AP-HP] Clinique Geoffroy Saint-Hilaire Centre Hospitalier Universitaire de Toulouse CHU Clermont-Ferrand CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble Clinique Saint-Omer [Blendecques]
• Publié dans Anaesthesia Critical Care & Pain Medicine le 27/10/2020

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• Type de publi. : Communication dans un congrès
• Date de publi. : 31/01/2026
• Auteurs : Philippe GardesLaurent CallegarinPierre PéfauWilfried LabartheMickaël Xompero
• Organismes : Institut national de recherches archéologiques préventives Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Institut de recherche sur l'architecture antique Centre National de la Recherche Scientifique Institut de recherche sur l'architecture antique Archeodunum Centre d'études et de recherches archéologiques en Gascogne

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• Type de publi. : Communication dans un congrès
• Date de publi. : 30/01/2026
• Auteurs : Carine CalastrencMarie-Claude BalFrançois BaleuxPierre CampmajoArthur ChironNicolas DobigeonMaialen GauthierLuc LapierreAntoine LaurentMatthieu Le BaillyMuriel LlubesNicolas MelladoBatiste MellierJosu Narbarte HernandesMagali PhilippeNicolas PoirierChristine RenduRomain Vercasson
• Organismes : Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Géographie de l'environnement Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Machine Learning Integrity & Safety Fairness Impact Trust Signal et Communications France, Amériques, Espagne, Sociétés, Pouvoirs, Acteurs Société Française de Photogrammétire et de télédétection Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Laboratoire Chrono-environnement (UMR 6249) Géosciences Environnement Toulouse Institut de recherche en informatique de Toulouse Géosciences Environnement Toulouse Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne] Géographie de l'environnement Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Géosciences Environnement Toulouse

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Résumé : Apport du Lidar HD de l'IGN et de la photogrammétrie par drone ✓ 23 années de prospection pédestres ✓ 882 structures inventoriées Apport du Lidar HD de l'IGN

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Fichiers liés : Seminaire_Terrae_30_janvier_2026.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 30/01/2026
• Auteurs : Carine CalastrencMarie-Claude BalFrançois BaleuxPierre CampmajoArthur ChironNicolas DobigeonMaialen GauthierLuc LapierreAntoine LaurentMatthieu Le BaillyMuriel LlubesNicolas MelladoBastiste MellierJosu Narbarte HernandezMagali PhilippeNicolas PoirierChristine RenduRomain Vercasson
• Organismes : Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Géographie de l'environnement Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Machine Learning Integrity & Safety Fairness Impact Trust Signal et Communications Institut National Polytechnique (Toulouse) France, Amériques, Espagne, Sociétés, Pouvoirs, Acteurs Centre National d'Études Spatiales [Toulouse] Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Laboratoire Chrono-environnement (UMR 6249) Géosciences Environnement Toulouse Structural Models and Tools in Computer Graphics Centre National de la Recherche Scientifique Géosciences Environnement Toulouse Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne] Géographie de l'environnement Cités, Territoires, Environnement et Sociétés Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Géosciences Environnement Toulouse

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Fichiers liés : Seminaire_Terrae_30_janvier_2026_V2.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 28/01/2026
• Auteurs : Long PhanAlice GattiZiwen HanNathaniel LiJosephina HuHugh ZhangSean ShiMichael ChoiAnish AgrawalArnav ChopraAdam KhojaRyan KimJason HausenloyOliver ZhangMantas MazeikaDaron AndersonTung NguyenMobeen MahmoodFiona FengSteven Y. FengHaoran ZhaoMichael YuVarun GangalChelsea ZouZihan WangJessica P. WangPawan KumarOleksandr PokutnyiRobert GerbiczSerguei PopovJohn-Clark LevinMstyslav KazakovJohannes SchmittGeoff GalgonAlvaro SanchezYongki LeeWill YeadonScott SauersMarc RothChidozie AguSøren RiisFabian GiskaSaiteja UtpalaZachary GiboneyGashaw M. GoshuJoan of Arc XavierSarah-Jane CrowsonMohinder Maheshbhai NaiyaNoah BurnsLennart FinkeZerui ChengHyunwoo ParkFrancesco Fournier-FacioJohn WydallisMark NandorAnkit SinghTim GehrungerJiaqi CaiBen MccartyDarling DucloselJungbae NamJennifer ZampeseRyan G. HoerrAras BachoGautier Abou LoumeAbdallah GalalHangrui CaoAlexis C GarretsonDamien SileoQiuyu RenDoru CojocPavel ArkhipovUsman QaziLianghui LiSumeet MotwaniChristian Schroeder de WittEdwin TaylorJohannes VeithEric SingerTaylor D. HartmanPaolo RissoneJaehyeok JinJack Wei Lun ShiChris G. WillcocksJoshua RobinsonAleksandar MikovAmeya PrabhuLongke TangXavier AlapontJustine Leon UroKevin ZhouEmily de Oliveira SantosAndrey Pupasov MaksimovEdward VendrowKengo ZenitaniJulien GuillodYuqi LiJoshua VendrowVladyslav KuchkinNg Ze-AnPierre MarionDenis EfremovJayson LynchKaiqu LiangAndrew GritsevskiyDakotah MartinezBen PagelerNick CrispinoDimitri ZvonkineNatanael Wildner FragaSaeed SooriOri PressHenry TangJulian SalazarSean R. GreenLina BrüsselMoon TwayanaAymeric DieuleveutT. Ryan RogersWenjin ZhangBikun LiJinzhou YangArun RaoGabriel LoiseauMikhail KalininMarco LukasCiprian ManolescuSubrata MishraAriel Ghislain Kemogne KamdoumTobias KreimanTad HoggAlvin JinCarlo BosioGongbo SunBrian P CoppolaTim TarverHaline HeidingerRafael SayousStefan IvanovJoseph M CavanaghJiawei ShenJoseph Marvin ImperialPhilippe SchwallerShaipranesh SenthilkumaAndres M BranAli DehghanAndres AlgabaBrecht VerbekenDavid NoeverRagavendran P VLisa SchutIlia SucholutskyEvgenii ZheltonozhskiiDerek LimRichard StanleyShankar SivarajanTong YangJohn MaarJulian WykowskiMartí OllerJennifer SandlinAnmol SahuYuzheng HuSara FishNasser HeydariArchimedes AprontiKaivalya RawalTobias Garcia VilchisYuexuan ZuMartin LacknerJames KoppelJeremy NguyenDaniil S. AntonenkoSteffi ChernBingchen ZhaoPierrot ArseneAlan GoldfarbSergey IvanovRafał PoświataChenguang WangDaofeng LiDonato CrisostomiAndrea AchilleosBenjamin MyklebustArchan SenDavid PerrellaNurdin KaparovMark H InlowAllen ZangElliott ThornleyDaniil OrelVladislav PoritskiShalev Ben-DavidZachary BergerParker WhitfillMichael FosterDaniel MunroLinh HoDan Bar HavaAleksey KuchkinRobert LauffDavid HolmesFrank SommerhageKeith SchneiderZakayo KazibweNate StambaughMukhwinder SinghIlias MagoulasDon ClarkeDae Hyun KimFelipe Meneguitti DiasVeit ElserKanu Priya AgarwalVictor Efren Guadarrama VilchisImmo KloseChristoph DemianUjjwala AnantheswaranAdam ZweigerGuglielmo AlbaniJeffery LiNicolas DaansMaksim RadionovVáclav RozhoňZiqiao MaChristian StumpMohammed BerkaniJacob PlatnickVolodymyr NevirkovetsLuke BaslerMarco PiccardoFerenc JeanplongNiv CohenJosef TkadlecPaul RosuPiotr PadlewskiStanislaw BarzowskiKyle MontgomeryAline MenezesArkil PatelZixuan WangJamie Tucker-FoltzJack StadeTom GoertzenFereshteh KazemiJeremiah MilbauerJohn Arnold AmbayAbhishek ShuklaYan Carlos Leyva LabradorAlan GivréHew WolffVivien RossbachMuhammad Fayez AzizYounesse KaddarYanxu ChenRobin ZhangJiayi PanAntonio TerpinNiklas MuennighoffHailey SchoelkopfEric ZhengAvishy CarmiAdam JonesJainam ShahEthan D. L. BrownKelin ZhuMax BartoloRichard WheelerAndrew HoShaul BarkanJiaqi WangMartin StehbergerEgor KretovKaustubh SridharZienab El-WasifAnji ZhangDaniel PydaJoanna TamDavid M. CunninghamVladimir GoryachevDemosthenes PatramanisMichael KrauseAndrew RedentiDaniel BugasDavid AldousJesyin LaiShannon ColemanMohsen BahalooJiangnan XuSangwon LeeSandy ZhaoNing TangMichael K. CohenMicah CarrollOrr ParadiseJan Hendrik KirchnerStefan SteinerbergerMaksym OvchynnikovJason O. MatosAdithya ShenoyBenedito Alves de Oliveira JuniorMichael WangYuzhou NiePaolo GiordanoPhilipp PetersenAnna Sztyber-BetleyPriti ShuklaJonathan CrozierAntonella PintoShreyas VermaPrashant JoshiZheng-Xin YongAllison TeeJérémy AndréolettiOrion WellerRaghav SinghalGang ZhangAlexander IvanovSeri KhouryHamid MostaghimiKunvar ThamanQijia ChenTran Quoc KhánhJacob LoaderStefano CavalleriHannah SzlykZachary BrownJonathan RobertsWilliam AlleyKunyang SunRyan StendallMax LamparthAnka ReuelTing WangHanmeng XuSreenivas Goud RaparthiPablo Hernández-CámaraFreddie MartinDmitry MalishevThomas PreuTomek KorbakMarcus AbramovitchDominic WilliamsonZiye ChenBiró BálintM Saiful BariPeyman KassaniZihao WangBehzad AnsarinejadLaxman Prasad GoswamiYewen SunHossam ElgnainyDaniel TorderaGeorge BalabanianEarth AndersonLynna KvistadAlejandro José MoyanoRajat MaheshwariAhmad SakorMurat EronIsaac C. McalisterJavier GimenezInnocent EnyekweAndrew Favre D. O.Shailesh ShahXiaoxiang ZhouFiruz KamalovRonald ClarkSherwin AbdoliTim SantensKhalida MeerHarrison K WangKalyan RamakrishnanEvan ChenAlessandro TomasielloG. Bruno de LucaShi-Zhuo LooiVinh-Kha LeNoam KoltNiels MündlerAvi SemlerEmma RodmanJacob DroriCarl J FossumMilind JagotaRonak PradeepHonglu FanTej ShahJonathan EicherMichael ChenKushal ThamanWilliam MerrillCarter HarrisJason GrossIlya GusevAsankhaya SharmaShashank AgnihotriPavel ZhelnovSiranut UsawasutsakornMohammadreza MofayeziSergei BogdanovAlexander PiperskiMarc CarauleanuDavid K. ZhangDylan LerRoman LeventovIgnat SorokoThorben JansenPascal LauerJoshua DuerschVage TaamazyanWiktor MorakWenjie MaWilliam HeldTran Đuc HuyRuicheng XianArmel Randy ZebazeMohanad MohamedJulian Noah LeserMichelle X YuanLaila YacarJohannes LenglerHossein ShahrtashEdson OliveiraJoseph W. JacksonDaniel Espinosa GonzalezAndy ZouMuthu ChidambaramTimothy ManikHector HaffendenDashiell StanderAli DasouqiAlexander ShenEmilien DucBita GolshaniDavid StapMikalai UzhouAlina Borisovna ZhidkovskayaLukas LewarkMátyás VinczeDustin WehrColin TangZaki HossainShaun PhillipsJiang MuzhenFredrik EkströmAngela HammonOam PatelNicolas RemyFaraz FarhidiGeorge MedleyForough MohammadzadehMadellene PeñaflorHaile KassahunAlena FriedrichClaire SparrowTaom SakalOmkar DhamaneAli Khajegili MirabadiEric HallmanMike BattagliaMohammad MaghsoudimehrabaniHieu HoangAlon AmitDave HulbertRoberto PereiraSimon WeberStephen MensahNathan AndreAnton PeristyyChris HarjadiHimanshu GuptaStephen MalinaSamuel AlbanieWill CaiMustafa MehkaryFrank ReidegeldAnna-Katharina DickCary FridayJasdeep SidhuWanyoung KimMariana CostaHubeyb GurdoganBrian WeberHarsh KumarTong JiangArunim AgarwalChiara CeconelloWarren S. VazChao ZhuangHaon ParkAndrew R. TawfeekDaattavya AggarwalMichael KirchhofLinjie DaiEvan KimJohan FerretYuzhou WangMinghao YanKrzysztof BurdzyLixin ZhangAntonio FrancaDiana T. PhamKang Yong LohJoshua RobinsonShreen GulGunjan ChhablaniZhehang DuAdrian CosmaColin WhiteRobin RibletPrajvi SaxenaJacob VotavaVladimir VinnikovEthan DelaneyShiv HalasyamaniSyed M. ShahidJean-Christophe MourratLavr VetoshkinRenas BachoVincent GinisAleksandr MaksapetyanFlorencia de la RosaXiuyu LiGuillaume MalodLeon LangJulien LaurendeauFatimah AdesanyaJulien PortierLawrence HollomVictor SouzaYuchen Anna ZhouYiğit YalınGbenga Daniel ObikoyaLuca ArnaboldiFilippo BigiKaniuar BachoPierre ClavierGabriel RecchiaMara PopescuNikita ShulgaNgefor Mildred TanwieThomas C. H. LuxBen RankColin NiAlesia YakimchykHuanxu LiuOlle HäggströmEmil VerkamaHimanshu NarayanHans GundlachLeonor Brito-SantanaBrian AmaroVivek VajipeyRynaa GroverYiyang FanGabriel Poesia Reis E SilvaLinwei XinYosi KratishJakub ŁuckiWen-Ding LiJustin XuKevin Joseph ScariaFreddie VargusFarzad HabibiEmanuele RodolàJules RobinsVincent ChengDeclan GrabbIda BosioTony FruhauffIdo AkovEve J. Y. LoHao QiXi JiangBen SegevJingxuan FanSarah MartinsonErik Y. WangKaylie HausknechtMichael P. BrennerMao MaoYibo JiangXinyu ZhangDavid AvagianEshawn Jessica ScipioMuhammad Rehan SiddiqiAlon RagolerJustin TanDeepakkumar PatilRebeka PlecnikAaron KirtlandRoselynn Grace MontecilloStephane DurandOmer Faruk BodurZahra AdoulMohamed ZekryGuillaume DouvilleAli KarakocTania C. B. SantosSamir ShamseldeenLoukmane KarimAnna LiakhovitskaiaNate ResmanNicholas FarinaJuan Carlos GonzalezGabe MaayanSarah HobackRodrigo de Oliveira PenaGlen ShermanHodjat MarijiRasoul PouriamaneshWentao WuGözdenur DemirSandra MendozaIsmail AlarabJoshua ColeDanyelle FerreiraBryan JohnsonHsiaoyun MillironMohammad SafdariLiangti DaiSiriphan ArthornthurasukAlexey ProninJing FanAngel Ramirez-TrinidadAshley CartwrightDaphiny PottmaierOmid TaheriDavid OutevskyStanley StepanicSamuel PerryLuke AskewRaúl Adrián Huerta RodríguezAbdelkader DendaneSam AliRicardo LorenaKrishnamurthy IyerSk Md SalauddinMurat IslamJuan GonzalezJosh DuceyRussell CampbellMaja SomrakVasilios MavroudisEric VergoJuehang QinBenjámin BorbásEric ChuJack LindseyAnil RadhakrishnanAntoine JallonI. M. J. McinnisAlex HooverSören MöllerSong BianJohn LaiTejal PatwardhanSummer YueAlexandr WangDan Hendrycks
• Organismes : Center for AI Safety Center for AI Safety Scale AI Center for AI Safety Scale AI Scale AI Scale AI Scale AI Scale AI Center for AI Safety Center for AI Safety Center for AI Safety Center for AI Safety Centre Inria de l'Université de Lille Laboratoire Jacques-Louis Lions Département de Mathématiques et Applications - ENS-PSL (UMR8553) Numerical Analysis, Geophysics and Ecology Machine Learning in Information Networks Laboratoire de Mathématiques d'Orsay Ecole Normale Supérieure Paris-Saclay Automatic Language Modelling and ANAlysis & Computational Humanities Systèmes complexes, automates et pavages Ecole Normale Supérieure Paris-Saclay Unité de Mathématiques Pures et Appliquées Centre de Mathématiques Appliquées de l'Ecole polytechnique Scale AI Scale AI Center for AI Safety
• Publié dans Nature le 29/10/2020

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Résumé : Benchmarks are important tools for tracking the rapid advancements in large language model (LLM) capabilities. However, benchmarks are not keeping pace in difficulty: LLMs now achieve more than 90% accuracy on popular benchmarks such as Measuring Massive Multitask Language Understanding1, limiting informed measurement of state-of-the-art LLM capabilities. Here, in response, we introduce Humanity’s Last Exam (HLE), a multi-modal benchmark at the frontier of human knowledge, designed to be an expert-level closed-ended academic benchmark with broad subject coverage. HLE consists of 2,500 questions across dozens of subjects, including mathematics, humanities and the natural sciences. HLE is developed globally by subject-matter experts and consists of multiple-choice and short-answer questions suitable for automated grading. Each question has a known solution that is unambiguous and easily verifiable but cannot be quickly answered by internet retrieval. State-of-the-art LLMs demonstrate low accuracy and calibration on HLE, highlighting a marked gap between current LLM capabilities and the expert human frontier on closed-ended academic questions. To inform research and policymaking upon a clear understanding of model capabilities, we publicly release HLE at https://lastexam.ai.

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Fichiers liés : s41586-025-09962-4.pdf

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 28/01/2026
• Auteurs : Roel AaijAhmed Sameh Wagih AbdelmottelebCarlos Abellan BetetaFernando Jesus AbudinénThomas AckernleyAyomide Matthew AdefisoyeBernardo AdevaMarco AdinolfiPatrik Harri AdlarsonChristina AgapopoulouChristine Angela AidalaZiad AjaltouniSimon AkarKazuyoshi AkibaMuzammil AktharPietro AlbicoccoJohannes AlbrechtRamunas AleksiejunasFederico AlessioPaula Alvarez CartelleRenaud AmalricSandra AmatoJake Lewis AmeyYasmine AmhisLiupan AnLucio AnderliniMartin AnderssonPasquale AndreolaMirco AndreottiSergio Andres EstradaAlessia AnelliDong AoCarolina ArataFlavio ArchilliZaratsyan AregMatteo ArgentonSergio Arguedas CuendisLisa ArnoneAlexander ArtamonovMarina ArtusoElie AslanidesRita Ataíde da SilvaMichele AtzeniBenjamin AudurierJuliette AuthierDavid BacherIrene Bachiller PereaSebastian BachmannMarie BachmayerJohn BackPablo Baladron RodriguezVladislav BalaguraAnna BalboniWander BaldiniZachary BaldwinLuca BalzaniHaoran BaoJuan Baptista de Souza LeiteCarlos Javier Barbero PretelMatteo BarbettiIvanildo Rui BarbosaRoger BarlowMikhail BarnyakovSergey BarsukWilliam BarterJustin BartzSaliha BashirBaasansuren BatsukhPiera BattistaAli BavarcheeAurelio BayAnja BeckMaik BeckerFranco BedeschiIgnacio BediagaNoah Albin BehlingSamuel BelinAlberto BellavistaKonstantin BelousIlia BelovIvan BelyaevGaya BenaneGiovanni BencivenniEli Ben-HaimAlexander BerezhnoyRoland BernetSergi Bernet AndresAlessandro BertolinFederico BettiJosh BexOleg BezshyykoSenjuti BhattacharyaMartin Stefan BiekerNicolo Vladi BiesuzAlice BiolchiniMatthew BirchFionn Caitlin Ros BishopAlexander BitadzeAndrea BizzetiThomas BlakeFrederic BlancJonah Evan BlankSteven BluskVladimir BocharnikovJulian Alexander BoelhauveOscar Boente GarciaThomas BoettcherAbhishek BohareAlexey BoldyrevCarolina BolognaniRiccardo BolzonellaRiccardo BonacciNikolay BondarAleksandar BordeliusFederica BorgatoSilvia BorghiMartino BorsatoJozef Tomasz BorsukElia BottalicoSonia Amina BouchibaMarcelo BovillThemistocles BowcockAlexandre BoyerConcezio BozziJames Daniel BrandenburgAlexandre Brea RodriguezNils BreerJolanta BrodzickaJames David BrownDavide BrunduEmma BuchananMarta Burgos MarcosAodhan Tomas BurkeChristopher BurrClarissa ButiJordy Sebastiaan ButterJan BuytaertWiktor ByczynskiSandro CadedduHao CaiYuman CaiAlois CailletRoberto CalabreseSaul Calderon RamirezLukas CaleficeMarta CalviMiriam Calvo GomezPatricia Camargo MagalhaesJose Ivan Cambon BouzasPierluigi CampanaAngel Fernando Campoverde QuezadaSimone CapelliMarco CaporaleLorenzo CapriottiRonald Gerardo Caravaca-MoraAngelo CarboneLidia Carcedo SalgadoRoberta CardinaleAlessandro CardiniPaolo CarnitiLeon David CarusAdrian Casais VidalRowina CasparyGianluigi CasseMarco CattaneoGiovanni CavalleroViola CavalliniSara CelaniIrene CelestinoSara CesareAbbie Jane ChadwickIbrahim ChahrourHao ChangMatthew CharlesPhilippe CharpentierEvridki ChatzianagnostouRacha CheaibMaximilien ChefdevilleChen ChenJou-An ChenShanzhen ChenZewen ChenAlex Chen HuMostafa CherifAleksei ChernovSerhii ChernyshenkoXenofon ChiotopoulosVeronika ChobanovaMarcin ChrzaszczAleksei ChubykinVladimir ChulikovPaolo CiambroneXabier Cid VidalGregory CiezarekPierfrancesco CifraPeter ClarkeMarco ClemencicHarry CliffJoel ClosierCarlos Eduardo Cocha ToapaxiVictor CocoJulien CoganEric CognerasLucian CojocariuSpencer Edward CollavitiPaula CollinsTommaso ColomboMarco ColonnaAlbert Comerma-MontellsLiliana CongedoJames ConnaughtonAndrea ContuNaomi CookeGiulio CordovaChristian Andres CoronelImanol CorredoiraAnthony CorreiaGloria CortiJozie Cottee MeldrumBenjamin CouturierDaniel Charles CraikMelissa Maria Cruz TorresMario Alberto Cubero CamposEsteban Curras RiveraRobert CurrieCesar Luiz da SilvaShakhzod DadabaevXinchen DaiElena Dall'OccoJeremy DalsenoCarmelo d'AmbrosioJessy DanielGabriella DarzeAlexander DavidsonJonathan Edward DaviesOscar de Aguiar FranciscoCamilla de AngelisFederico de BenedettiJan de BoerKristof de BruynStefano de CapuaMichel de CianUlisses de Freitas Carneiro da GracaErika de LuciaJussara de MirandaLeandro de PaulaMarilisa de SerioPatrizia de SimoneFabio de VellisJacco de VriesFrancesco DebernardisDaniel DecampSam Michael DekkersLuigi del BuonoBlaise DelaneyJianqiao DengVadym DenysenkoOlivier DeschampsFrancesco DettoriBiplab DeyPasquale Di NezzaIgor DiachkovSergey DidenkoShuchong DingYiyang DingLucas DittmannVasyl DobishukAleksandrina DochevaAlex Patrick DohenyChenzhi DongAmanda May DonohoeFrancesca DordeiAlberto dos ReisAndrew Jay DowlingLea Marie Sophie DreyfusWeisong DuanPiotr Jakub DudaLaurent DufourViacheslav DukPaolo DuranteMaciej DurasJohn Matthew DurhamOzgur DurmusAgnieszka DziurdaAlexey DzyubaSajan EasoEllinor EcksteinUlrik EgedeArtem EgorychevVictor EgorychevStephan EisenhardtEnoch EjopuLars EklundMohamed ElashriDaniel Guillermo Elizondo BlancoJan Hendrik EllbrachtScott ElyAlexandru EneJonas Nathanael EschleTimothy EvansFederica FabianoSaba FaghihLucas FalcaoBo FangRiccardo FantechiLisa FantiniMaria FariaKeira Gwyn FarmerFloris Patrick Jan FassinDavide FazziniLukasz Jerzy FelkowskiMingjie FengAlvaro Fernandez CasaniMiguel Fernandez GomezAlex Daniel FernezFabio FerrariFernando Ferreira RodriguesMartina FerrilloMassimiliano Ferro-LuzziSergey FilippovRosa Anna FiniMassimiliano FioriniMiroslaw FirlejKamil Leszek FischerDillon Scott FitzgeraldConor FitzpatrickTomasz FiutowskiFrederic FleuretAlex FominMarianna FontanaLucas Arthur ForemanRoger FortyDaniel Foulds-HoltVinicius Franco LimaManuel Franco SevillaMarkus FrankEdoardo FranzosoGiulia FrauChristoph FreiDavid Anthony FridayJinlin FuQuentin FühringTommaso FulghesuGiuliana GalatiMaria Domenica GalatiAbraham Gallas TorreiraDomenico GalliSilvia GambettaMiriam GandelmanPaolo GandiniBilal Ahmad GanieHan GaoRui GaoTian-Qi GaoYang GaoYuanning GaoYuxi GaoLuis Miguel Garcia MartinPaula Garcia MorenoJulián García PardiñasParker Taittinger GardnerLluis GarridoClara GasparArsenii GavrikovLouis Lenard GerkenEvelina GersabeckMarco GersabeckTimothy GershonSimon GhizzoZahra GhorbanimoghaddamFotis Ioannis GiasemisValerie GibsonHenryk Karol GiemzaAlexander Leon GilmanMatteo GiovannettiAlessandra GioventùLucas George GirardeyMaciej Artur GizaFabian Christoph GlaserVladimir GligorovCarla GöbelLarysa Golinka-BezshyykoElisabet GolobardesDmitry GolubkovAndrey GolutvinSergio Gomez FernandezWojciech GomulkaIsadora Gonçales VazFernanda Goncalves AbrantesMateusz GoncerzGuanghua GongJames Andrew GoodingIgor Vladimirovich GorelovClaudio GottiEkaterina GovorkovaJascha Peter GrabowskiLuis Alberto Granado CardosoEugeni GraugésElena GraveriniLuke GrazetteGiacomo GrazianiAlexandru Tudor GrecuNathan Allen GrieserLucia GrilloSergey GromovChenxi GuMarco GuariseLaetitia GuerryAbdul-Kerim GuseinovEvgeny GushchinYury GuzThierry GysKai Sebastian HabermannThomas HadavizadehChristos HadjivasiliouGuido HaefeliChristophe HaenSamuel James HakenGeorge HallettPhoebe Meredith HamiltonJan HammerichQundong HanXiaoxue HanStephanie Hansmann-MenzemerLei HaoNeville HarnewThomas James HarrisMarie HartmannSabin HashmiJibo HeNathan Barry HeatleyAndreea-Irina HedesFrederic HemmerConor HendersonRaoul HendersonRiley Dylan Leslie HendersonArthur Marius HennequinKarol HennessyLouis HenryJames Daniel HerdPaula Herrero GasconJohannes HeuelAnna-Maria HeynAdlène HicheurGuillermo Hijano MendizabalJoshua Ethan HorswillRuiwen HouYingrui HouDylan Cameron HoustonNed Francis HowarthWenhua HuXiaofan HuWouter HulsbergenRoss John HunterMikhail HushchynDavid HutchcroftMarek IdzikDmitrii IlinPhilip IltenAleksandr IniukhinAxel IohnerArtur IshteevKuzma IvshinHendrik JageSergio Javier Jaimes EllesSune JakobsenTomas JakoubekEddy JansBrij Kishor JashalAbolhassan JawaheryChanka JayaweeraAlexander Michael JelavicVukan JevticZekun JiaEmily Kaiyin JiangXiaojie JiangYi JiangYuyang JiangEsteban Jimenez MoyaNicholas JindalMalcolm JohnAllen Cris John Rubesh RajanDaniel JohnsonChristopher JonesSalil JoshiBeat JostJuan Jose Juan CastellaNathan JurikIzabela JuszczakKamila Karina KalecinskaDimitrios 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LaneGaia LanfranchiChristoph LangenbruchJan LangerThomas LathamFederico LazzariCristina LazzeroniRenaud Le GacHo Sang LeeRegis LefèvreAlexander LeflatSergey LegotinMarion LehurauxEdgar Lemos CidOlivier LeroyTadeusz LesiakEzra Douglas LesserBlake LeveringtonAnfeng LiChen LiChing-Hua LiHengne LiJiuzhao LiKechen LiLanxing LiManshu LiPeilian LiPei-Rong LiQinze LiTiange LiTianqi LiYanru LiYiming LiYujie LiZhengchen LianQiming LiangXixin LiangZhihua LiangSimone LibralonAlisha LightbodyChuangxin LinTai-Hua LinRolf LindnerHenry James LintonRoman LitvinovDuanqing LiuFrank Xiangyu LiuGuoming LiuKai LiuShuaiyi LiuWeijie LiuYiming LiuYing LiuYiwei LiuGustavo Alejandro Loachamin OrdonezIsaac Graciano LoboAniol Lobo SalviaAngelo LoiThomas LongFelipe Cesario Laterza LopesJose LopesAlbert Lopez HuertasCristina Lopez IribarnegaraySaúl López SoliñoQiuchan LuChiara LucarelliDonatella LucchesiMiriam Lucio MartinezYiheng LuoAnna LupatoEleonora LuppiKate LynchXiao-Rui LyuGe MaHeng MaSerena MaccoliniFrederic MachefertFlorin MaciucBridget MackInnes MackayLauren Grace MackeyLakshan Ram Madhan MohanMarcus Jonathan MaduraiDaniel MagdalinskiDmitrii MaisuzenkoJakub Jacek MalczewskiSneha MaldeLorenzo MalentaccaAlexander MalininTimofei MaltsevGiulia MancaGiampiero MancinelliChiara MancusoRafel Manera EscaleroFederico ManganellaDaniele ManuzziDaniele MarangottoJean François MarchandRadoslav MarchevskiUmberto MarconiEdoardo MarianiSaverio MarianiCarla Marin BenitoJörg MarksAlexander Mclean MarshallLucas MartelGabriele MartelliGiuseppe MartellottiLoris MartinazzoliMaurizio MartinelliDaniel Guillermo Martinez GomezDiego Martinez SantosFernando Martinez VidalAlexia Martorell GranollersAndré MassafferriRosen MatevAbhijit MathadViacheslav MatiuninClara MatteuzziKara Renee MattioliAndrea MauriEmilie MauriceJoan MauricioPierre Paul Louis MayencourtJose Mazorra de CosMichal MazurekDavid Mazzanti TaranconMichael MccannNiall Thomas MchughAndrew McnabRonan McnultyBrian MeadowsDmytro MelnychukDiego Mendoza GranadaPablo Eduardo Menendez Valdes PerezFanjie MengMarcel MerkAndrea MerliLucas Meyer GarciaDexing MiaoHan MiaoMikhail MikhasenkoDiego Alejandro MilanesAlessandro MinottiElisa MinucciTristan MirallesBiljana MitreskaDominik Stefan MitzelRoxana Maria MocanuAtanu ModakLeandra MoeserRazvan-Daniel MoiseEsteban Felipe Molina CardenasTitus MombächerMatthew David MonkTobias Alexandre MonnardStephane MonteilAngel Morcillo GomezGianfranco MorelloMichael Joseph MorelloMaurice Pierre MorgenthalerAlice MoroJakub MoronWouter MorrenAdam Benjamin MorrisAndrew George MorrisRaymond MountainZeqing MuEmir MuhammadFranz MuheimMick MulderKatharina MüllerFederico Muñoz-RojasRebecca MurtaViktor MytrochenkoParas NaikTatsuya NakadaRaja NandakumarTara NanutGauri NapoletanoIrina NastevaMatthew NeedhamEvgeniia NekrasovaNicola NeriSebastian NeubertNiko NeufeldPetr NeustroevJanina NicoliniDavide NicotraElisabeth Maria NielNikolay NikitinLorenzo NisiQile NiuBenedict Kamoni NjokiPedro NogarolliPiet NoggaCamille NormandJulio Novoa FernandezGabriel Matthew NowakCynthia NunezHavva Hasret NurAgnieszka Oblakowska-MuchaVladimir ObraztsovThomas OeserArtem OkhotnikovOleksandr OkhrimenkoRudolf OldemanFederica OlivaErnest Olivart PinoMicol OloccoRyunosuke Hugo O'NeilJuan Sebastian Ordonez SotoDonata OsthuesJuan Martin Otalora GoicocheaPatrick OwenMaria Aranzazu OyangurenOzlem OzcelikFrancesco PaciollaAdam PadeeKlaas Ole PadekenBhagyashree PagareTommaso PajeroAntimo PalanoLuca PaliniMatteo PalutanChucheng PanXiaofan PanStefano PanebiancoStella PaniskakiGennady PanshinLorenzo PaolucciAntonios PapanestisMarco PappagalloLuciano PappalardoCheryl PappenheimerChristopher ParkesDhruvanshu ParmarGiovanni PassalevaDaniele PassaroAlessandra PastoreMitesh PatelJairus Tristan PatocClaudia PatrignaniAntara PaulChristopher James PawleyAntonio PellegrinoJi PengXuanjia PengMonica Pepe AltarelliStefano PerazziniDmitrii PereimaHugo Pereira da CostaMaria Pereira MartinezAsier Pereiro CastroCilicia Uzziel PerezPascal PerretAnn-Kathrin PerrevoortAlberto PerroMichael Jacob PetersKonstantinos PetridisAlessandro PetroliniSerena PezzuloJacob PfallerHang PhamLorenzo PicaMauro PicciniLorenzo PiccoloBoleslaw PietrzykGuillaume PietrzykRiccardo Nunzio PilatoDavide PinciFlavio PisaniMarco PizzichemiVlad-Mihai PlacintaMaximo Plo CasasusThomas PoeschlFrancesco PolciMarco Poli LenerAnton PoluektovNatalia PolukhinaIvan PolyakovErica PolycarpoSebastien PonceDmitry PopovKatharina Luise PoppStanislav PoslavskiiKodassery PrasanthClaire ProuveDaniele ProvenzanoValery PugatchAlfonso Puicercus GomezGiovanni PunziJackson Reeves PybusQucheng QianWenbin QianNing QinRenato QuaglianiRaul Iraq Rabadan TrejoRuta RaczJonas RademackerMatteo RamaManuel Ramírez GarcíaVictoria Ramos de OliveiraMiguel Ramos PernasMurilo RangelFedor RatnikovGerhard RavenMiguel Rebollo de MiguelFederico RediJake ReichFlorian ReissZan RenP.K ResmiMiquel Ribalda GalvezRoberto RibattiGabriel RicartDomenico RiccardiStefania RicciardiKate Abigail RichardsonMary Richardson-SlipperFelix RiehnKurt RinnertPatrick RobbeGary RobertsonEduardo RodriguesAlejandro Rodriguez AlvarezEmilio Xose Rodriguez FernandezJairo Alexis Rodriguez LopezEfren Rodriguez RodriguezJonas Malte RoenschAlexander RogachevAlexander RogovskiyDavid Leonhard RolfPhilipp RoloffVladimir RomanovskiyAntonio Romero VidalGabriele RomoliniFederico RonchettiTianze RongMarcello RotondoShreya RoyMatthew Scott RudolphMiguel Ruiz DiazRamon Angel Ruiz FernandezJoan Ruiz VidalJose Javier Saavedra-AriasJuan Jose Saborido SilvaMedaer Sacha Emile R.Naylya SagidovaDebashis SahooNiladribihari SahooBiagio SaittaMatteo SalomoniIzaac SanderswoodRoberta SantacesariaCibran Santamarina RiosMarco SantimariaLeonardo SantoroEmanuele SantovettiAlessandro SaputiDanila SaraninAndrej SarnatskiyGediminas SarpisMindaugas SarpisCelestina SatrianoAlessia SattaMiroslav SaurDarya SavrinaHalime SazakFrancesco SborzacchiAlessandro ScarabottoStefan SchaelSigrid ScherlManuel SchillerHeinrich SchindlerMichael SchmellingBurkhard SchmidtNicolas SchmidtSebastian SchmittHannah SchmitzOlivier SchneiderAndreas SchopperNicole SchulteMarie Helene SchuneGeorg SchweringBarbara SciasciaAugusto SciuccatiGeorge William ScrivenIlya SegalSara SellamAlexander SemennikovThomas Christian SengerMara Senghi SoaresAntonino SergiNicola SerraLorenzo SestiniAlex SeutheBorja Sevilla SanjuanYiduo ShangDesmond Mzamo ShangaseMikhail ShapkinRashi SharmaIvan ShchemerovLesya ShchutskaTara ShearsLev ShekhtmanZhihong ShenShuqi ShengVladimir ShevchenkoBoan ShiJingyuan ShiQi ShiWenjie ShiYuya ShimizuEvgenii ShmaninRoman ShorkinJoseph David ShupperdRafael Silva CoutinhoGabriele SimiSaverio SimoneMrityunjoy SinghaNicola SkidmoreTomasz SkwarnickiMark SlaterEluned SmithMark SmithLais Soares LavraMichael SokoloffPaul SolerAnatoly SolominAleksandr SolovevKsenia SolovievaNiclas SommerfeldRongrong SongYunxuan SongYuxiang SongYintong SongFelipe Luan Souza de AlmeidaBruno Souza de PaulaKarol Mateusz SowaElisabetta Spadaro NorellaEugenia SpedicatoJannis Guido SpeerPatrick SpradlinFederico StagniMarian StahlSascha StahlSeophine StanislausMaria Zofia StefaniakOlaf SteinkampDaria StrekalinaYangjie SuFidan SuljikJiayin SunJinyi SunLiang SunDaniel SundfeldWilliam SutcliffePeter SvihraVolodymyr SvintozelskyiKrzysztof SwientekFrancesca SwystunAdam SzabelskiTomasz SzumlakYinghua TanYingao TangYuxuan TangMartin Duy TatJuan Adrian Teijeiro JimenezAleksandr TerentevFrancesco TerzuoliFrederic TeubertEric ThomasDaniel James David ThompsonAlexander Robert Thomson-StrongHanae TilquinVincent TisserandStephane t'JampensMark TobinTodor Georgiev TodorovLuca TomassettiGiorgia TonaniXingyu TongTheraa TorkLuca Toscanoda Yu TouCarina TripplGiulia TuciNiels TuningLennart Henning UeckerArtur UklejaDaniel Joachim UnverzagtAbhinaba UpadhyayBenjamin UrbachAndrii UsachovAndrey UstyuzhaninUlrich UwerVincenzo VagnoniAugustas VaitkeviciusVictoria Valcarce CadenasGiovanni ValentiNuria Valls CanudasJan van EldikHubert van HeckeEric van HerwijnenCharlotte Barbara van HulseRaphael van LaakMaarten van VeghelGerardo VasquezRicardo Vazquez GomezPablo Vazquez RegueiroCarlos Vázquez SierraStefania VecchiJavier Velilla SernaJaap VelthuisMichele VeltriAravindhan VenkateswaranMichele VerdogliaMika VesterinenWren VetensDavid Vico BenetPol Vidrier VillalbaMaria Vieites DiazXavier Vilasis-CardonaEva Vilella FiguerasAndrea VillaPascal VincentBeatriz VivacquaFelicia Carolin VolleDorothea Vom BruchNikolai VoropaevKimberley VosConstantinos VrahasJan Peter WagnerJohn WalshEliot Jane WaltonGuanyue WanAnqi WangBoxin WangChishuai WangGanrong WangHong-Jian WangJialu WangJianchun WangJianqiao WangJike WangMengzhen WangMenghao WangNanyang WangRui WangXiao WangXiaolin WangXiaohan WangYilong WangYuhao WangYinghao WangZhenzi WangZiyi WangJake Alexander WardMark WaterlaatNigel WatsonDavid WebsdaleYajing WeiZheng WeidaJohn WendelBenedict Donald C WesthenryCallum James WhiteMark WhiteheadEleanor WhiterAidan Richard WiederholdDirk WiednerMax WiegertjesCharlie WildGuy WilkinsonMichael K WilkinsonMike WilliamsMorag Jean WilliamsMark Richard James WilliamsRichard Morgan WilliamsSean James WilliamsZak WilliamsFergus WilsonMichael Andreas WinnWojciech WislickiMariusz WitekLukas WitolaTom WolfElla WoodGuy WormserStephen WottonHangyi WuJie WuXiangyu WuYanxi WuZhenhong WuKenneth WyllieShu XianZhiyu XiangYuehong XieTianyu XingAo XuLiangjun XuMenglin XuZehua XuZhihao XuZijun XuSimran YadavKang YangXueting YangYouhua YangYewon YangZhenwei YangVsevolod YeroshenkoHo Yin Dereck YeungHang YinXiaoyue YinChenxu YuJiesheng YuXuhao YuanYuan YuanJilberto Antonio Zamora SaaMikhail ZavertyaevMilosz ZdybalFrancesco ZenesiniCheng ZengMing ZengChenjia ZhangDongliang ZhangJianyu ZhangLiming ZhangRanyu ZhangShunan ZhangShulei ZhangYanxi ZhangYuge ZhangZhicai ZhangYa ZhaoAlexey ZhelezovShuang ZhengXutao ZhengYangheng ZhengTianwen ZhouXiaokang ZhouYixiong ZhouValeriia ZhovkovskaLinxuan ZhuXianglei ZhuXiaoyu ZhuYibo ZhuValery ZhukovJiahui ZhuoDavide ZulianiGianluca Zunica
• Organismes : Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire Leprince-Ringuet Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie

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Résumé : A search for the rare decay $B^{+} \to \bar Λp μ^{+} μ^{-}$ is performed using proton-proton collision data recorded by the LHCb experiment at a center-of-mass energy of $\sqrt{s}= 13$ TeV, corresponding to an integrated luminosity of 5.4 fb$^-1$. An excess of events is found with respect to the background-only expectation, with a signal significance of 3.5 standard deviations, in the low invariant-mass region of $m(\bar Λp)<2.8$ GeV/$c^2$. The branching fraction is measured to be ${\cal B}_{\rm low}({B^{+}}\to {\bar Λp μ^{+} μ^{-}})=\left(1.70 ^{+0.65}_{-0.56}(\rm stat) \pm 0.17(\rm syst) \pm 0.14(\rm ext)\right) \times 10^{-8}$, where the last uncertainty is due to external inputs on ${\cal B}(B^+\to{J/ψ\bar Λp})\times {\cal B}({J/ψ}\to{μ^+μ^-})$. With no significant signal observed in the high $m(\bar Λp)$ region above 2.8 GeV/$c^2$, an upper limit is set to be ${\cal B}_{\rm high}(B^{+}\to {\bar Λp μ^{+} μ^{-}})<2.8\,(3.7) \times 10^{-9}$ at the $90\%$ ($95\%$) confidence level.

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Source

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 27/01/2026
• Auteurs : Aram HayrapetyanVladimir MakarenkoArmen TumasyanWolfgang AdamLisa BenatoThomas BergauerMarko DragicevicCristina GiordanoPriya Sajid HussainManfred JeitlerNatascha KrammerAng LiDietrich LikoMark MatthewmanJochen SchieckRobert SchöfbeckDennis SchwarzMaryam ShooshtariMangesh SonawaneWolfgang WaltenbergerClaudia-Elisabeth WulzTahys JanssenHyejin KwonDaniel Ocampo HenaoThomas van LaerPierre van MechelenJas BierkensNordin BreugelmansJorgen d'HondtSoumya DansanaAlexandre de MoorMartin DelcourtFelix HeyenYanwen HongPavlo KashkoSteven LowetteInna MakarenkoDenise MüllerJuhee SongStefaan TavernierMichael TytgatGerrit Patrick van OnsemSenne van PutteDavid VanneromBugra BilinBarbara ClerbauxAloke Kumar DasIsabelle de BruynGilles de LentdeckerHugues EvardLaurent FavartParaskevas GianneiosAli KhalilzadehFakhri Alam KhanAndrea MalaraMuhammad Aamir ShahzadArchana SharmaLaurent ThomasMax Vanden BemdenCatherine Vander VeldePascal VanlaerFengwangdong ZhangMaarten de CoenDidar DoburGul GokbulutDavid MarckxKirill SkovpenAdina Maria TomaruNiels van den BosscheJan van der LindenJules VandenbroeckLiam WezenbeekHenriette Aarup PetersenSamuel BeinAnna BeneckeAgni BethaniGiacomo BrunoAlessandra CappatiJerome de Favereau de JeneretChristophe DelaereFrancisco Gameiro CasalinhoAndrea GiammancoAhmet Oguz GuzelVincent LemaitreJindrich LidrychPaul MalekPaola MastrapasquaSemra TurkcaparGilvan AlvesMapse Barroso Ferreira FilhoEduardo CoelhoCarsten HenselDiego Matos FigueiredoThales Menezes de OliveiraClemencia Mora HerreraPatricia Rebello TelesMariana SoeiroEdmilson José Tonelli ManganoteAntonio Vilela PereiraWalter Luiz Aldá JúniorHelena Brandao MalbouissonWagner CarvalhoJose ChinellatoMatheus Costa ReisEliza Melo da CostaGustavo Gil da SilveiraDilson de Jesus DamiaoSandro Fonseca de SouzaRaphael Gomes de SouzaSilas JesusTulio Laux KuhnMatheus MacedoKevin Mota AmariloLuiz MundimHelio NogimaJoao Pedro PinheiroAlberto SantoroAndre SznajderMauricio ThielFelipe Torres da Silva de AraujoCesar Augusto BernardesLuigi CalligarisFlorian DamasThiago TomeiEduardo de Moraes GregoresBruno Lopes da CostaIsabela Maietto SilverioPedro G MercadanteSergio F NovaesBreno OrzariSandra PadulaValerie ScheurerAleksandar AleksandrovGeorgy AntchevPetar DanevRoumyana HadjiiskaPlamen IaydjievMariana ShopovaGeorgi SultanovAnton DimitrovLeander LitovBorislav PavlovPeicho PetkovAnton PetrovSumit KeshriDavid Nicolas Laroze NavarreteShalini ThakurWilliam BrooksTongguang ChengTahir JavaidLong WangLi YuanZhen HuZhengchen LiangJinfeng LiuXining WangHeng YangGuo-Ming ChenHe-Sheng ChenMingshui ChenYe ChenQingfeng HouXiaonan HouFabio IemmiChun-Hua JiangHongbo LiaoGeliang LiuZhenan LiuJia-Ning SongShaowei SongJunquan TaoChu WangJin WangHuaqiao ZhangJingzhou ZhaoAntonis AgapitosYong BanAlexandra Carvalho Antunes de OliveiraSen DengBotao GuoQianying GuoChuqiao JiangAndrew LevinCongqiao LiQiang LiYajun MaoSitian QianSi-Jin QianXuelong QinClaudio QuarantaXiaohu SunDayong WangJin WangMingtao ZhangYuzhe ZhaoChen ZhouShuai YangZhengyun YouKhawla JaffelNan LuGerry BauerZhipeng CuiBolin LiHui WangKai YiJingqing ZhangYuji LiYilin ZhouZhen LinChenfeng LuMeng XiaoCarlos AvilaDiego Andres Barbosa TrujilloAndrés CabreraCarlos FlorezJorge FragaJose Antonio Reyes VegaCésar RendónManuel RodriguezAnderson Alexis Ruales BarbosaJosé David Ruiz AlvarezNikola GodinovicDamir LelasAna SculacMarko KovacAndro PetkovicToni SculacPedrame BargassaVuko BrigljevicBhakti Kanulal ChitrodaDinko FerencekKresimir JakovcicAndrei StarodumovTatjana SusaAlexandros AttikisKonstantinos ChristoforouSotiroulla KonstantinouChristos LeonidouLeonidas PaizanosFotios PtochosPanos A RazisHans RykaczewskiHalil SakaAnton StepennovMiroslav FingerMichael FingerEdy AyalaEdgar Carrera JarrinSherif ElgammalAli Ellithi KamelAhmed HusseinHemida MohammedMario KadastikTorben LangeChristine NielsenJoosep PataMartti RaidalNorman SeebaLaurits TaniErik BrückenAnna MilievaKenneth OsterbergMikko VoutilainenFrancisco Ignacio Garcia 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Résumé : A search for dark matter particles produced in association with a Higgs boson decaying to a bottom quark-antiquark pair in proton-proton collisions at $\sqrt{s}$ = 13 TeV is presented. The data, collected with the CMS detector at the LHC, correspond to an integrated luminosity of 101 fb$^{-1}$. The analysis is performed in exclusive categories targeting both Lorentz-boosted (merged) and resolved b jet pair topologies, covering a wide range of Higgs boson transverse momentum. A statistical combination is made with a previous search using data collected in 2016 and corresponding to an integrated luminosity of 35.9 fb$^{-1}$. The observed data agree with the standard model background predictions. Constraints are placed on models predicting new particles or interactions, such as those in the simplified frameworks of baryonic-Z' and 2HDM+a, where the latter is a type-II two-Higgs-doublet model featuring a heavy pseudoscalar with an additional light pseudoscalar. Upper limits at 95% confidence level are set on the production cross section for these models. For the baryonic-Z' model, Z' boson masses below 2.25 TeV are excluded for a dark matter particle candidate mass of 1 GeV. In the 2HDM+a model, heavy pseudoscalar masses between 850 and 1300 GeV are excluded for a light pseudoscalar mass of 350 GeV.

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