Philippe JEAN-PIERRE

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• Type de publi. : Communication dans un congrès
• Date de publi. : 07/02/2011
• Auteurs : Dmitry LevshovThierry MichelY. YuzyukChristophe VoisinLaurent AlvarezSébastien BergerPhilippe RoussignolJean-Louis Sauvajol
• Organismes : Faculty of Physics Laboratoire Charles Coulomb Faculty of Physics Laboratoire Pierre Aigrain Laboratoire Charles Coulomb Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Charles Coulomb

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Résumé : The temperature dependence of the Raman spectrum of a gelatine-based composite material doped with single-walled carbon nanotubes (SWNT@gelatin) is reported [1]. A significant up-shift of the G-mode frequency is observed when the temperature is decreased from room temperature to 20 K. This frequency shift is significantly stronger than the one found for pure thermal effects. In contrast, the features of the radial breathing modes (frequencies and width) display no significant change in the same temperature range. These results are well understood by considering a uniaxial strain on the nanotube induced by the thermal expansitivity mismatch between the nanotube and the surrounding matrix [2,3]. These conclusions are in good agreement with photoluminescence experiments performed on the same samples [4]. References [1] D. Levshov, J. Phys. Chem. C 2010, 114, 16210-16214. [2] S. Cronin, Phys. Rev. Lett. 2004, 93, 167401. [3] G. Wu, Phys. Rev. B 2005, 72, 115411. [4] S. Berger, J. Appl. Phys. 2009, 105, 094323.

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• Type de publi. : Communication dans un congrès
• Date de publi. : 07/02/2011
• Auteurs : Adrien BrilhaultSlim KammounOlivier GutierrezPhilippe TruilletChristophe Jouffrais
• Organismes : Etude de L’Interaction Personne SystèmE Etude de L’Interaction Personne SystèmE Etude de L’Interaction Personne SystèmE Etude de L’Interaction Personne SystèmE Centre National de la Recherche Scientifique Etude de L’Interaction Personne SystèmE Image & Pervasive Access Lab Laboratoire Cherchons Pour Voir

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• Type de publi. : Communication dans un congrès
• Date de publi. : 07/02/2011
• Auteurs : Benjamin LangloisDamien GarrotCyrielle RoqueletChristophe VoisinJean‐sébastien LauretThierry MichelPhilippe RoussignolClaude DelalandeEmmanuelle Deleporte
• Organismes : Laboratoire Pierre Aigrain Laboratoire de Photonique Quantique et Moléculaire Laboratoire de Photonique Quantique et Moléculaire Laboratoire Pierre Aigrain Laboratoire de Photonique Quantique et Moléculaire Laboratoire Charles Coulomb Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire de Photonique Quantique et Moléculaire

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Résumé : Single-Wall Carbon Nanotubes (SWNTs) non-covalently functionalized with organic molecules have proven to be a very promising light-harvesting system. The goal is to combine the unique transport and optical properties of nanotubes with the wide tunability of organic molecules properties. Among those molecules, porphyrins, a precursor of photosynthetic centers, show a strong absorption in the visible that is already used in dye sensitized hybrid solar cells [1]. Porphyrins link to SWNTs through π-stacking interaction which preserves most of the intrinsic properties of the SWNTs, in contrast with covalent functionalization. Moreover, the coupling is still strong enough to induce new functionalities. It was recently shown that efficient excitation energy transfer (EET) can occur in such system [2,3]. The very high quantum yield reported in this system suggests that the EET mechanism must occur on an ultrafast time-scale [4]. In order to characterize the nature of the EET mechanism, we investigate its dynamics at a subpicosecond time scale, by means of pump-probe spectroscopy. We show that the ground state recovery time of porphyrin in the compound is reduced by several orders of magnitude compared to the case or free porphyrin (Fig. 1). Concomitantly, a strong bleaching signal is observed on the optical resonances of the nanotubes showing an ultrafast population build-up upon excitation of the porphyrin (Fig. 2). We conclude that the energy transfer occurs on a time scale shorter than 100fs and that the surrounding of SWNTs by porphyrins does not affect the relaxation dynamics. References [1] W. M. Campbell, et al., The Journal of Physical Chemistry C, 111, 11760 (2007). [2] G. Magadur, et al., ChemPhysChem, 9, 1250 (2008).pp. 200-205. [3] J. P. Casey, et al., Journal of Materials Chemistry, 18, 1510 (2008). [4] C. Roquelet, et al., Applied Physics Letters, 97, 141918 (2010).

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• Type de publi. : Communication dans un congrès
• Date de publi. : 07/02/2011
• Auteurs : Cyrielle RoqueletDamien GarrotJean‐sébastien LauretChristophe VoisinValérie AlainPhilippe RoussignolJacques A. DelaireEmmanuelle Deleporte
• Organismes : Laboratoire de Photonique Quantique et Moléculaire Laboratoire de Photonique Quantique et Moléculaire Laboratoire de Photonique Quantique et Moléculaire Laboratoire Pierre Aigrain Laboratoire de Photophysique et Photochimie Supramoléculaires et Macromoléculaires Laboratoire Pierre Aigrain Laboratoire de Photophysique et Photochimie Supramoléculaires et Macromoléculaires Institut d'Alembert Laboratoire de Photonique Quantique et Moléculaire

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• Type de publi. : Article dans une revue
• Date de publi. : 07/02/2011
• Auteurs : Grégory MollionPhilippe Yolka
• Organismes : Centre de Recherches Juridiques Centre d'Etudes et de Recherches sur le Droit, l'Histoire et l'Administration Publique
• Publié dans La Semaine Juridique. Administrations et collectivités territoriales le 23/10/2020

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Résumé : Par une décision du 22 octobre 2010 concernant les suites de l'avalanche de Montroc (Chamonix, février 1999), le Conseil d'État annule un arrêt d'appel aux termes duquel les fautes alléguées n'entretenaient pas de lien direct avec le préjudice invoqué. Ce faisant, il invite la juridiction de renvoi à rechercher l'existence éventuelle d'une faute commise par l'administration lors du classement du secteur concerné en zone constructible

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• Type de publi. : Article dans une revue
• Date de publi. : 03/02/2011
• Auteurs : Marion LudwigNuno PalhaCorinne C. TorhyValérie BriolatEmma Colucci-GuyonMichel BrémontPhilippe HerbomelPierre BoudinotJean-Pierre Levraud
• Organismes : Macrophages et Développement de l'Immunité Macrophages et Développement de l'Immunité Unité de recherche Virologie et Immunologie Moléculaires Macrophages et Développement de l'Immunité Macrophages et Développement de l'Immunité Unité de recherche Virologie et Immunologie Moléculaires Macrophages et Développement de l'Immunité Unité de recherche Virologie et Immunologie Moléculaires Macrophages et Développement de l'Immunité
• Publié dans PLoS Pathogens le 27/10/2020

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Résumé : The progression of viral infections is notoriously difficult to follow in whole organisms. The small, transparent zebrafish larva constitutes a valuable system to study how pathogens spread. We describe here the course of infection of zebrafish early larvae with a heat-adapted variant of the Infectious Hematopoietic Necrosis Virus (IHNV), a rhabdovirus that represents an important threat to the salmonid culture industry. When incubated at 24 °C, a permissive temperature for virus replication, larvae infected by intravenous injection died within three to four days. Macroscopic signs of infection followed a highly predictable course, with a slowdown then arrest of blood flow despite continuing heartbeat, followed by a loss of reactivity to touch and ultimately by death. Using whole-mount in situ hybridization, patterns of infection were imaged in whole larvae. The first infected cells were detectable as early as 6 hours post infection, and a steady increase in infected cell number and staining intensity occurred with time. Venous endothelium appeared as a primary target of infection, as could be confirmed in fli1:GFP transgenic larvae by live imaging and immunohistochemistry. Disruption of the first vessels took place before arrest of blood circulation, and hemorrhages could be observed in various places. Our data suggest that infection spread from the damaged vessels to underlying tissue. By shifting infected fish to a temperature of 28 °C that is non-permissive for viral propagation, it was possible to establish when virus-generated damage became irreversible. This stage was reached many hours before any detectable induction of the host response. Zebrafish larvae infected with IHNV constitute a vertebrate model of an hemorrhagic viral disease. This tractable system will allow the in vivo dissection of host-virus interactions at the whole organism scale, a feature unrivalled by other vertebrate models.

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Fichiers liés : Whole-Body Analysis of a Viral Infection Vascular Endothelium is a Primary Target.PDF

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• Type de publi. : Article dans une revue
• Date de publi. : 02/02/2011
• Auteurs : Olivia BoyerGeneviève BenoitOlivier GribouvalFabien NevoMarie-Josèphe TêteJacques DantalBrigitte Gilbert-DussardierGuy TouchardAlexandre KarrasClaire PresneJean-Pierre GrünfeldChristophe LegendreDominique JolyPhilippe RieuNabil MohsinThierry HannedoucheValerie MoalMarie-Claire GublerIsabelle BroutinGéraldine MolletCorinne Antignac
• Organismes : Néphropathies héréditaires et rein en développement Néphropathies héréditaires et rein en développement Néphropathies héréditaires et rein en développement Neuropathies héréditaires et rein en développement Service de néphrologie pédiatrique [CHU Necker] Unit of Nephrology & Clinical Immunology Centre hospitalier universitaire de Poitiers = Poitiers University Hospital Service de Néphrologie [CHU Poitiers] Service de Néphrologie [HEGP] Service de Néphrologie [Amiens] Service de néphrologie pédiatrique [CHU Necker] Service de néphrologie adultes [CHU Necker] Évolution, génomes, comportement et écologie Hôpital universitaire Robert Debré [Reims] Sultan Qaboos University Department of Nephrology, Sun Yat-sen University Centre de néphrologie et transplantation rénale [Hôpital de la Conception - APHM] Neuropathies héréditaires et rein en développement Laboratoire de cristallographie et RMN biologiques Néphropathies héréditaires et rein en développement Néphropathies héréditaires et rein en développement
• Publié dans Journal of the American Society of Nephrology le 26/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/02/2011
• Auteurs : Sarah Beseme NambotinLydie LefrancoisXavier SainsilyPascale BerthillonMiran KimJack R. WandsMichele ChevallierPierre JalinotJean-Yves ScoazecChristian TrépoFabien ZoulimPhilippe Merle
• Organismes : Service d'hépatologie et de gastroentérologie Service d'hépatologie et de gastroentérologie Service d'hépatologie et de gastroentérologie E16 The Liver Research Center The Liver Research Center Département d'Anatomie Pathologique Laboratoire de Biologie Moléculaire de la Cellule Laboratoire Central d'Anatomie et de Cytologie Pathologiques [Hôpital Edouard Herriot - HCL] Service d'hépatologie et de gastroentérologie Service d'hépatologie et de gastroentérologie Service d'hépatologie et de gastroentérologie
• Publié dans Journal of Hepatology le 23/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/02/2011
• Auteurs : Matthieu MullerPhilippe DessogneMarc BaronJean-Michel PicquenotCéline RiopelBrigitte DiologentPierre-François DupréMichel Collet
• Organismes : Service de Gynécologie-Obstétrique service de chirurgie Groupe d'étude des proliférations lymphoïdes Service de radiologie Service de Gynécologie-Obstétrique Service de Gynécologie-Obstétrique Groupe d'Etude de la Thrombose de Bretagne Occidentale
• Publié dans Annales de Pathologie le 24/10/2020

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Résumé : Aggressive fibromatosis (desmoid tumour) of the breast is a rare tumour that accounts only for 0.2% of primary breast tumours. This is a benign mesenchymal tumour that develops from muscular fasciae and aponeuroses. It is characterized by its local evolution and its tendency to relapse without metastasizing. Wide radical resection should be attempted whenever possible. Positive margins at resection and reoperation are associated with a high risk of local recurrence. The role of radiotherapy and of medical treatments- especially anti-estrogens - remains unclear. We report here the case of desmoid tumour of the breast arising in a 9-year-old little girl.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/02/2011
• Auteurs : Fabrice LegrosThierry AncelleEric CaumesMarie-Laure DardéJean DelmontRobert DescloitresPatrick ImbertLudovic de GentileR. MiglianiPatrick OuvrardVincent RobertGérard DuvalletNathalie BoulangerFabrice ChandreNathalie Colin de VerdierePaul Henri ConsignyPascal DelaunayJérôme DepaquitBarbara DoudierMichel FrancFlorence MoulinFrédéric PagèsAurélie PrangeIsabelle QuatresousPhilippe SaviucStéphane AuvinFrancis CarsuzzaAmandine CochetFrédéric DarrietAnne DemantkeElisabeth ElefantAnna-Bella FaillouxChristophe LagneauCatherine C. PecquetGuy La RucheFrédéric SorgeArnaud TarantolaCatherine VauzelleFaiza AjanaAlexis ArmengaudJean Paul BoutinSandrine ChevallierSuzanne GagnonSabine GentyRomain GirodNadine GodineauClaude GuigenYves HatchuelClaude HengyArezki IzriDominique JeanFrédéric JourdainIsabelle LamauryB. MarchouValérie MassonPhilippe MinodierAlice PérignonSylvie PiccoliBéatrice QuinetAndré YebakimaJulien Santi-RoccaSherri Smith
• Organismes : "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group Epidémiologie, stratégies thérapeutiques et virologie cliniques dans l'infection à VIH Neuroépidémiologie Tropicale et Comparée Aix-Marseille Université - Faculté de médecine "Personal Protection Against Vectors" working group Hôpital d'Instruction des Armées Begin [Saint-Mandé, France] "Personal Protection Against Vectors" working group Département d'Épidémiologie et de Santé Publique Nord "Personal Protection Against Vectors" working group Diversity, ecology, evolution & Adaptation of arthropod vectors Centre d’Ecologie Fonctionnelle et Evolutive Physiopathologie et Médecine Translationnelle Virulence bactérienne précoce : fonctions cellulaires et contrôle de l'infection aiguë et subaiguë Vector Control Group Service des Maladies Infectieuses et Tropicales Centre Médical de l'Institut Pasteur Laboratoire de Parasitologie-Mycologie "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group Service de neuropédiatrie [Debré] "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group Vector Control Group "Personal Protection Against Vectors" working group CHU Trousseau [APHP] Génétique Moléculaire des Bunyavirus "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group Entomologie médicale [Cayenne, Guyane française] Service de parasitologie "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group Service des maladies infectieuses Service Maladies infectieuses et tropicales [CHU Toulouse] "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group Centre de la Démoustication "Personal Protection Against Vectors" working group "Personal Protection Against Vectors" working group
• Publié dans Parasite le 02/11/2020

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Résumé : Recent events with the first cases of local transmission of chikungunya and dengue fever virus in southern France by Aedes albopictus, adding to the nuisance and potential vectors that can be encountered when traveling in tropical or sub-tropical countries, has shown the value of a reflection on the Personal protection against vectors (PPAV). It is seen during an outbreak of vector-borne disease, or simply because of nuisance arthropods, that our fellow citizens try to protect themselves individually by using an arsenal of resources available on the market. Yet most of these means have been neither checked for effectiveness or safety tests, however, essential. Travellers, staff on mission or assignment, are looking for specific information on how to protect themselves or their families. Health workers had at their disposal so far indications that vary widely from one source to another. Therefore it seemed important to the Society of Travel Medicine (SMV) and the French Society of Parasitology (SFP) to initiate a reflection on this theme. This reflection took the form of recommendations for good practice, following the outline established by the French High Health Authority (HAS). The aim was to gather all relevant information, verified and validated and the format to be used not only by health personnel (doctors, pharmacists, nurses), but also by travel agents and individuals. This document highlights the need to take into account the risk of vector-borne diseases, some deadly, and the benefit of various methods of personal protection. The choice of methods is clearly oriented towards those whose effectiveness has been proven and potential risks assessed. The paper finally proposes two decision trees based on the transmission type (day or night) and kind of stay (short or roaming, long and steady). It concerns travellers, but also expatriates, residents and nomads.

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Fichiers liés : parasite2011181p93.pdf

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