Philippe Jean-Pierre

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• Type de publi. : Article dans une revue
• Date de publi. : 01/08/2025
• Auteurs : Camille RobinFabien RollotMathilde LefortRomain CaseySandra VukusicGuillaume MatheyJonathan CironJérôme de SèzeBruno StankoffElisabeth MaillartAurélie RuetPierre M. LabaugeArnaud KwiatkowskiHélène ZéphirCaroline PapeixGilles-Louis DeferChristine Lebrun-FrénayThibault MoreauDavid-Axel LaplaudEric BergerPierre ClavelouEric ThouvenotOlivier HeinzlefJean PelletierOlivier CasezBertrand BourreAbir WahabLaurent MagySolène MoulinJean-Philippe CamdessanchéInès DoghriMariana SarovKarolina HankiewiczCorinne PottierAmélie dos SantosÉric ManchonMaya TchikviladzeChantal NifleAnne KerbratGilles EdanEmmanuelle Le PageLaure Michel
• Organismes : Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre d'Investigation Clinique [Rennes] Université Claude Bernard Lyon 1 Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Observatoire Français de la Sclérose En Plaques [Lyon] Fondation Eugène Devic EDMUS Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre d'Investigation Clinique [Rennes] Université Claude Bernard Lyon 1 Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Observatoire Français de la Sclérose En Plaques [Lyon] Fondation Eugène Devic EDMUS Université Claude Bernard Lyon 1 Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Observatoire Français de la Sclérose En Plaques [Lyon] Fondation Eugène Devic EDMUS INterdisciplinarité en Santé Publique Interventions et Instruments de mesure complexes Service de neurologie [CHRU Nancy] Institut Toulousain des Maladies Infectieuses et Inflammatoires Centre Ressources et Compétences sclérose en plaques (CRC-SEP) [CHU Toulouse] Centre Hospitalier Universitaire [Strasbourg] CIC Strasbourg Institut du Cerveau = Paris Brain Institute Centre de Ressources et de Compétences Sclérose en Plaques (CRC-SEP) Paris CHU Pitié-Salpêtrière [AP-HP] Centre de Ressources et de Compétences Sclérose en Plaques (CRC-SEP) Paris Centre Hospitalier Universitaire de Bordeaux Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale Centre Hospitalier Régional Universitaire [Montpellier] Université de Montpellier Université catholique de Lille - Faculté de théologie Groupement des Hôpitaux de l'Institut Catholique de Lille Centre Hospitalier Régional Universitaire [CHU Lille] Centre de Ressources et de Compétences sur la Sclérose en Plaques (CRC-SEP) [Lille] Hôpital Fondation Adolphe de Rothschild = Adolphe de Rothschild Foundation Hospital Université Paris Cité CHU Caen Normandie – Centre Hospitalier Universitaire de Caen Normandie Centre Hospitalier Universitaire de Nice UR2CA - URRIS - Unité de Recherche sur le syndrome Radiologique ISolé et maladies apparentées Service de Neurologie générale, vasculaire et dégénérative (CHU de Dijon) Centre de Recherche en Transplantation et Immunologie - Center for Research in Transplantation and Translational Immunology Centre d'investigation clinique (CIC) de Nantes -CIC Plurithématique Centre Hospitalier Régional Universitaire de Besançon CHU Louise Michel [Clermont-Ferrand] Neuro-Dol Centre de Ressources et de Compétences sur la Sclérose en Plaques (CRC-SEP) [Clermont-Ferrand] Service de Neurologie [CHU Nimes] Institut de Génomique Fonctionnelle Centre hospitalier intercommunal de Poissy/Saint-Germain-en-Laye - CHIPS [Poissy] Centre de Ressources et de Compétences Sclérose en Plaques (CRC-SEP) Paris Neurologie, maladies neuro-musculaires [Hôpital de la Timone - APHM] Pôle Psychiatrie et Neurologie [Grenoble] Université Grenoble Alpes CHU Rouen Hôpital Henri Mondor CHU Limoges Hôpital universitaire Robert Debré [Reims] Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] Hôpital Bretonneau Service de neurologie [Le Kremlin Bicêtre] Centre Hospitalier Universitaire de La Réunion hôpital NOVO Centre hospitalier universitaire de Poitiers = Poitiers University Hospital CIC Poitiers – Centre d'investigation clinique de Poitiers Centre Hospitalier de Gonesse Hôpital Foch [Suresnes] Centre Hospitalier de Versailles André Mignot Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre d'Investigation Clinique [Rennes] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre d'Investigation Clinique [Rennes] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre d'Investigation Clinique [Rennes] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Microenvironment and B-cells: Immunopathology,Cell Differentiation, and Cancer Centre d'Investigation Clinique [Rennes]
• Publié dans Neurology le 01/11/2020

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Résumé : Background and objectives: The therapeutic strategy in patients with late-onset MS (LOMS) remains poorly defined. In this study, we aimed to evaluate both clinical and MRI outcomes between 2 cohorts of patients with relapsing-remitting LOMS treated or not yet treated. Methods: Patients with relapsing-remitting MS were included for the analysis if disease onset occurred after 55 years and if they had at least one follow-up visit. The primary outcome was time to first relapse between 2 matched groups of patients with LOMS (treated and not yet treated). Secondary outcomes were as follows: (1) time to first confirmed disability progression (CDP), (2) time to first progression independent of relapse activity (PIRA) event, (3) time to secondary progression (SPMS), (4) time to first MRI activity, and (5) serious infection incidence rates (IIRs). For the comparative analyses, we adopted a time-dependent propensity score matching approach. Results: A total of 881 patients fulfilled the inclusion criteria. The mean (SD) age at onset was 59.9 (4.43) years. After applying propensity score matching, 436 patients were matched. The mean (SD) follow-up duration was 5.2 (4.27) years in the treated group and 5.0 (3.86) years in the not-yet-treated group. Mean (SD) time to first relapse was significantly longer in the treated group compared with the not-yet-treated group (7.0 years [0.33] vs 5.4 years [0.33]; p = 0.001). Mean (SD) time to first MRI activity was significantly longer in the treated group (5.9 years [0.33] vs 5.0 years [0.33]; p = 0.049). However, the mean time to CDP, PIRA, or SPMS was not different between the 2 groups (difference = 0.32 years; p = 0.585 for CDP; difference = 0.40 years; p = 0.442 for PIRA; difference = -0.02 years; p = 0.952 for SPMS). No increase in serious IIRs was observed with an incidence rate ratio of 0.38 (95% CI 0.07-2.10, p = 0.265) in the never-treated group compared with the treated one. Discussion: This study demonstrates a beneficial effect of disease-modifying therapy (DMT) on disease activity in patients with LOMS but without significant impact on disability progression. Main limitations are linked to the challenge of data collection and to the baseline imbalances between the 2 groups. Classification of evidence: This study provides Class III evidence that in patients with LOMS, treatment with DMTs is associated with a longer time to first relapse compared with those not treated with DMTs.

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• Type de publi. : Article dans une revue
• Date de publi. : 31/07/2025
• Auteurs : Pauline JaubertCamille LoretTanya StojkovicShahram AttarianNathalie Bonello‐palotFrançoise BouhourJean-Philippe CamdessanchéJulien CassereauJean-Baptiste ChansonPascal CintasAlain CréangeFlorence EsselinSteeve GenestetSophie GiordanoCyril GitiauxMarine Guillaud‐batailleArnaud IsapofDeiva KumaranCéline LabeyrieVincent LaugelSarah Leonard‐louisPierre LozeronLaurent MagySandra MercierPhilippe MerleMaud MichaudGuillaume NicolasElisabeth OllagnonYann PereonAngela PumaVianney PoinsignonSusana Quijano RoyGuilhem SoleCéline TardLéo VidoniAnne‐sophie LiaAndoni Echaniz-Laguna
• Organismes : Marseille medical genetics - Centre de génétique médicale de Marseille Filière Neuromusculaire Marseille medical genetics - Centre de génétique médicale de Marseille CHU Amiens-Picardie
• Publié dans European Journal of Neurology le 22/10/2020

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Résumé :

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Fichiers liés : Euro J of Neurology - 2025 - Jaubert - Nationwide Phenotypic and Genotypic Characterisation of 103 Patients With SH3TC2.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 30/07/2025
• Auteurs : Eric Nguyen-KhacPhilippe MerleHajer Ben KhadhraAmaddeo GiulianaThomas DecaensThomas UguenJean-Frédéric BlancNathalie Ganne-CarrieMohamed BouattourStéphane CattanChristine SilvainGhassan RiachiJean-Marie PeronRodolphe AntyJean-Pierre BronowickiAurore BaronGeorges-Philippe PageauxVéronique Loustaud-RattiFrédéric ObertiManon AllaireSylvain ManfrediYasmina Ben MerabetIsabelle Ollivier-HourmandMarie LequoyJean-Baptiste NousbaumMoana Gelu-SimeonLucien GradosPierre NahonCharlotte CostentinJean Claude BarbareGérard DucournauOlivier Ganry
• Organismes : Groupe de Recherche sur l'alcool et les pharmacodépendances - UMR INSERM_S 1247 UPJV Service d'Hépato Gastroenterologie [CHU Amiens-Picardie] CIC CHU Lyon (inserm) Service d'Hépato Gastroenterologie [CHU Amiens-Picardie] Institut Mondor de Recherche Biomédicale Université Paris-Est Créteil Val-de-Marne - Paris 12 CHU Henri Mondor [Créteil] Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre Hospitalier Universitaire de Bordeaux Hôpital Avicenne [AP-HP] Centre de recherche sur l'Inflammation Hôpital Beaujon [AP-HP] Registre EPIMAD Centre Hospitalier Régional Universitaire [CHU Lille] Centre hospitalier universitaire de Poitiers = Poitiers University Hospital Nutrition, Inflammation et axe Microbiote-Intestin-Cerveau Institute for Research and Innovation in Biomedicine Université de Rouen Normandie Service d'Hépato-Gastroentérologie [CHU Rouen] Centre Hospitalier Universitaire de Toulouse Centre méditerranéen de médecine moléculaire Centre Hospitalier Universitaire de Nice Centre Hospitalier Régional Universitaire de Nancy Nutrition-Génétique et Exposition aux Risques Environnementaux Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) Centre Hospitalier Sud Francilien Centre Hospitalier Régional Universitaire [Montpellier] Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB) Biologie moléculaire et cellulaire des microorganismes Service de Bactériologie, Virologie, Hygiène [CHU Limoges] Centre Hospitalier Universitaire d'Angers Centre de recherche sur l'Inflammation CHU Pitié-Salpêtrière [AP-HP] Lipides - Nutrition - Cancer [Dijon - U1231] CHU Dijon Hôpital Paul Brousse CHU Caen Normandie – Centre Hospitalier Universitaire de Caen Normandie CHU Saint-Antoine [AP-HP] Centre Hospitalier Régional Universitaire de Brest CHU Pointe-à-Pitre / Abymes [Guadeloupe] CHU Amiens-Picardie Hôpital Avicenne [AP-HP] Centre Hospitalier Universitaire [CHU Grenoble] CHU Amiens-Picardie CHU Amiens-Picardie CHU Amiens-Picardie CHirurgie, IMagerie et REgénération tissulaire de l’extrémité céphalique - Caractérisation morphologique et fonctionnelle - UR UPJV 7516
• Publié dans European Journal of Gastroenterology & Hepatology le 22/10/2020

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Résumé : Background The burden of hepatocellular carcinoma (HCC) increases worldwide. We report the current landscape of HCC, in France. Methods Carcinome HépatocellulaIrE en France (CHIEF) is a national, prospective, observational cohort initiated in 2019 with the aim of including 5000 patients with HCC, with a 5-year follow-up for each. CHIEF Epidemio 2000, is the first global analysis. Results In September 2021, 2043 patients were included in 32 centers. We analyzed 1640 patients, 86% men, 68-year-old, BMI 26.8. 70.8% of patients had cirrhosis (MELD score 9, Child–Pugh A in 77.8%, and portal hypertension in 39%. Liver disease was related to alcohol 58.5%, metabolic syndrome 39%, and virus 23.3%. HCC was confirmed by histology in 46.3%. The Milan criteria fulfilled 32.9%, median AFP 39 ng/ml, 5.9% portal thrombosis, and 10.7% metastases. BCLC classes 0, A, B, C, and D were 6.1, 29.8, 28.8, 32.1, and 3.2%, respectively. HCC was detected during a surveillance program in 35.2% associated with better survival ( P < 0.001). Median follow-up was 17.76 months (29.1% deaths). The 6, 12, and 18 months overall survival rates were 84.9% (95% CI: 82.8–87), 76.7% (95% CI: 74.2–79.2), 69.3% (95% CI: 66.4–72.3). One-year survival for BCLC 0, A, B, C, and D was at 95.6, 89.7, 81.7, 54.9, and 40%, respectively ( P < 0.0001). First-line treatment was curative, locoregional, or systemic in 40.5, 36.2, and 19.2%, with 1-year survival at 92.9, 82.2, and 57.8%, respectively ( P < 0.0001). Atezolizumab–bevacizumab yielded a median overall survival of 17.05 months versus nine for TKI ( P < 0.0001). Conclusion In real-life data, metabolic syndrome becomes the second cause of HCC in France. The 1-year survival rates are high for all treatments applied, and Immunotherapy yields similar results than in trials.

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 29/07/2025
• Auteurs : Roel AaijAhmed Sameh Wagih AbdelmottelebCarlos Abellan BetetaFernando Jesus AbudinénThomas AckernleyAyomide Matthew AdefisoyeBernardo AdevaMarco AdinolfiPatrik Harri AdlarsonChristina AgapopoulouChristine Angela AidalaZiad AjaltouniSimon AkarKazuyoshi AkibaPietro AlbicoccoJohannes AlbrechtFederico AlessioZakariya AliouchePaula Alvarez CartelleRenaud AmalricSandra AmatoJake Lewis AmeyYasmine AmhisLiupan AnLucio AnderliniMartin AnderssonPasquale AndreolaMirco AndreottiSergio Andres EstradaAlessia AnelliDong AoFlavio ArchilliZaratsyan AregMatteo ArgentonSergio Arguedas CuendisAlexander ArtamonovMarina ArtusoElie AslanidesRita Ataíde da SilvaMichele AtzeniBenjamin AudurierJuliette AuthierDavid BacherIrene Bachiller PereaSebastian BachmannMarie BachmayerJohn BackPablo Baladron RodriguezVladislav BalaguraAnna BalboniWander BaldiniLuca BalzaniHaoran BaoJuan Baptista de Souza LeiteCarlos Javier Barbero PretelMatteo BarbettiIvanildo Rui BarbosaRoger BarlowMikhail BarnyakovSergey BarsukWilliam BarterJustin BartzSaliha BashirBaasansuren BatsukhPiera BattistaAurelio BayAnja BeckMaik BeckerFranco BedeschiIgnacio BediagaNoah Albin BehlingSamuel BelinKonstantin BelousIlia BelovIvan BelyaevGaya BenaneGiovanni BencivenniEli Ben-HaimSean BensonAlexander BerezhnoyRoland BernetSergi Bernet AndresAlessandro BertolinChristopher BetancourtFederico BettiJosh BexIaroslava BezshyikoOleg BezshyykoJihyun BhomMartin Stefan BiekerNicolo Vladi BiesuzPierre BilloirAlice BiolchiniMatthew BirchFionn Caitlin Ros BishopAlexander BitadzeAndrea BizzetiThomas BlakeFrederic BlancJonah Evan BlankSteven BluskVladimir BocharnikovJulian Alexander BoelhauveOscar Boente GarciaThomas BoettcherAbhishek BohareAlexey BoldyrevCarolina BolognaniRiccardo BolzonellaRiccardo BonacciNikolay BondarAleksandar BordeliusFederica BorgatoSilvia BorghiMartino BorsatoJozef Tomasz BorsukElia BottalicoSonia Amina BouchibaMarcelo BovillThemistocles BowcockAlexandre BoyerConcezio BozziJames Daniel BrandenburgAlexandre Brea RodriguezNils BreerJolanta BrodzickaArnau Brossa GonzaloJames David BrownDavide BrunduEmma BuchananLaura BuonincontriMarta Burgos MarcosAodhan Tomas BurkeChristopher BurrJordy Sebastiaan ButterJan BuytaertWiktor ByczynskiSandro CadedduHao CaiYuman CaiAlois CailletRoberto CalabreseSaul Calderon RamirezLukas CaleficeStefano CaliMarta CalviMiriam Calvo GomezPatricia Camargo MagalhaesJose Ivan Cambon BouzasPierluigi CampanaDaniel Hugo Campora PerezAngel Fernando Campoverde QuezadaSimone CapelliLorenzo CapriottiRonald Gerardo Caravaca-MoraAngelo CarboneLidia Carcedo SalgadoRoberta CardinaleAlessandro CardiniPaolo CarnitiLeon David CarusAdrian Casais VidalRowina CasparyGianluigi CasseMarco CattaneoGiovanni CavalleroViola CavalliniSara CelaniSara CesareAbbie Jane ChadwickIbrahim ChahrourHao ChangMatthew CharlesPhilippe CharpentierEvridki ChatzianagnostouRacha CheaibMaximilien ChefdevilleChen ChenJou-An ChenShanzhen ChenZewen ChenAleksei ChernovSerhii ChernyshenkoXenofon ChiotopoulosVeronika ChobanovaMarcin ChrzaszczAleksei ChubykinVladimir ChulikovPaolo CiambroneXabier Cid VidalGregory CiezarekPierfrancesco CifraPeter ClarkeMarco ClemencicHarry CliffJoel ClosierCarlos Eduardo Cocha ToapaxiVictor CocoJulien CoganEric CognerasLucian CojocariuSpencer Edward CollavitiPaula CollinsTommaso ColomboMarco ColonnaAlbert Comerma-MontellsLiliana CongedoAndrea ContuNaomi CookeChristian Andres CoronelImanol CorredoiraAnthony CorreiaGloria CortiJozie Cottee MeldrumBenjamin CouturierDaniel Charles CraikMelissa Maria Cruz TorresEsteban Curras RiveraRobert CurrieCesar Luiz da SilvaShakhzod DadabaevLingyun DaiXinchen DaiElena Dall'OccoJeremy DalsenoCarmelo d'AmbrosioJessy DanielPhilippe d'ArgentGabriella DarzeAlexander DavidsonJonathan Edward DaviesOscar de Aguiar FranciscoCamilla de AngelisFederico de BenedettiJan de BoerKristof de BruynStefano de CapuaMichel de CianUlisses de Freitas Carneiro da GracaErika de LuciaJussara de MirandaLeandro de PaulaMarilisa de SerioPatrizia de SimoneFabio de VellisJacco de VriesFrancesco DebernardisDaniel DecampSam Michael DekkersLuigi del BuonoBlaise DelaneyHans Peter DembinskiJianqiao DengVadym DenysenkoOlivier DeschampsFrancesco DettoriBiplab DeyPasquale Di NezzaIgor DiachkovSergey DidenkoShuchong DingYiyang DingLucas DittmannVasyl DobishukAleksandrina DochevaChenzhi DongAmanda May DonohoeFrancesca DordeiAlberto dos ReisAndrew Jay DowlingWeisong DuanPiotr Jakub DudaMaciej Wojciech DudekLaurent DufourViacheslav DukPaolo DuranteMaciej DurasJohn Matthew DurhamOzgur DurmusAgnieszka DziurdaAlexey DzyubaSajan EasoEllinor EcksteinUlrik EgedeArtem EgorychevVictor EgorychevStephan EisenhardtEnoch EjopuLars EklundMohamed ElashriJan Hendrik EllbrachtScott ElyAlexandru EneJonas Nathanael EschleSevda EsenTimothy EvansFederica FabianoSaba FaghihLucas FalcaoBo FangRiccardo FantechiLisa FantiniMaria FariaKeira Gwyn FarmerDavide FazziniLukasz Jerzy FelkowskiMingjie FengMauricio FeoAlvaro Fernandez CasaniMiguel Fernandez GomezAlex Daniel FernezFabio FerrariFernando Ferreira RodriguesMartina FerrilloMassimiliano Ferro-LuzziSergey FilippovRosa Anna FiniMassimiliano FioriniMiroslaw FirlejKamil Leszek FischerDillon Scott FitzgeraldConor FitzpatrickTomasz FiutowskiFrederic FleuretAlex FominMarianna FontanaLucas Arthur ForemanRoger FortyDaniel Foulds-HoltVinicius Franco LimaManuel Franco SevillaMarkus FrankEdoardo FranzosoGiulia FrauChristoph FreiDavid Anthony FridayJinlin FuQuentin FühringYuki FujiiTommaso FulghesuGiuliana GalatiMaria Domenica GalatiAbraham Gallas TorreiraDomenico GalliSilvia GambettaMiriam GandelmanPaolo GandiniBilal Ahmad GanieHan GaoRui GaoTian-Qi GaoYang GaoYuanning GaoYuxi GaoLuis Miguel Garcia MartinPaula Garcia MorenoJulián García PardiñasParker Taittinger GardnerKunal GargLluis GarridoClara GasparArsenii GavrikovLouis Lenard GerkenEvelina GersabeckMarco GersabeckTimothy GershonSimon GhizzoZahra GhorbanimoghaddamLuca GiambastianiFotis Ioannis GiasemisValerie GibsonHenryk Karol GiemzaAlexander Leon GilmanMatteo GiovannettiAlessandra GioventùLucas George GirardeyMaciej Artur GizaFabian Christoph GlaserVladimir GligorovCarla GöbelLarysa Golinka-BezshyykoElisabet GolobardesDmitry GolubkovAndrey GolutvinSergio Gomez FernandezWojciech GomulkaIsadora Gonçales VazFernanda Goncalves AbrantesMateusz GoncerzGuanghua GongJames Andrew GoodingIgor Vladimirovich GorelovClaudio GottiEkaterina GovorkovaJascha Peter GrabowskiLuis Alberto Granado CardosoEugeni GraugésElena GraveriniLuke GrazetteGiacomo GrazianiAlexandru Tudor GrecuLex Marinus GreevenNathan Allen GrieserLucia GrilloSergey GromovChenxi GuMarco GuariseLaetitia GuerryVasilisa GuliaevaPaul Andre GüntherAbdul-Kerim GuseinovEvgeny GushchinYury GuzThierry GysKai Sebastian HabermannThomas HadavizadehChristos HadjivasiliouGuido HaefeliChristophe HaenGeorge HallettPhoebe Meredith HamiltonJan HammerichQundong HanXiaoxue HanStephanie Hansmann-MenzemerLei HaoNeville HarnewThomas James HarrisMarie HartmannSabin HashmiJibo HeFrederic HemmerConor HendersonRaoul HendersonRiley Dylan Leslie HendersonArthur Marius HennequinKarol HennessyLouis HenryJames Daniel HerdPaula Herrero GasconJohannes HeuelAdlène HicheurGuillermo Hijano MendizabalJoshua Ethan HorswillRuiwen HouYingrui HouNed Francis HowarthJifeng HuWenhua HuXiaofan HuWouter HulsbergenRoss John HunterMikhail HushchynDavid HutchcroftMarek IdzikDmitrii IlinPhilip IltenAleksandr IniukhinArtur IshteevKuzma IvshinHendrik JageSergio Javier Jaimes EllesSune JakobsenEddy JansBrij Kishor JashalAbolhassan JawaheryChanka JayaweeraVukan JevticEmily Kaiyin JiangXiaojie JiangYi JiangYuyang JiangMalcolm JohnAllen Cris John Rubesh RajanDaniel JohnsonChristopher JonesThomas Peter JonesSalil JoshiBeat JostJuan Jose Juan CastellaNathan JurikIzabela JuszczakDimitrios KaminarisSergii KandybeiMichael James KaneYouen KangChandiprasad KarMatthias KaracsonDmitrii KarpenkovAnni KauniskangasJacob William KautzMichal Krzysztof KazaneckiFloris KeizerMatthew KenzieTjeerd KetelBasem KhanjiAnastasiia KharisovaSergei KholodenkoGaelle KhreichThomas KirnVeronica Soelund KirsebomOuail KitouniSuzanne KlaverNico KleijneKonrad KlimaszewskiMateusz Rafal KmiecSerhii KoliievLars KolkAnatoly KonoplyannikovPawel KopciewiczPatrick KoppenburgAlexander KorchinMikhail KorolevIgor KostiukOleksander KotSofia KotriakhovaElizabeth Marie KowalczykAnastasiia KozachukPolina KravchenkoLeonid KravchukMichal KrepsPavel KrokovnyWojciech KrupaWojciech KrzemienOleksandr KshyvanskyiSebastian Antoni KubisMarcin KucharczykVasily KudryavtsevEvgenia KulikovaAndrzej KupscVolodymyr KushnirBogdan KutsenkoIgor KyryllinDaniel LacarrerePaloma Laguarta GonzalezAdriano LaiAndrea LampisDavide LancieriniClara Landesa GomezJohn Jake LaneGaia LanfranchiChristoph LangenbruchJan LangerOliver LantwinThomas LathamFederico LazzariCristina LazzeroniRenaud Le GacHo Sang LeeRegis LefèvreAlexander LeflatSergey LegotinMarion LehurauxEdgar Lemos CidOlivier LeroyTadeusz LesiakEzra Douglas LesserBlake LeveringtonAnfeng LiChen LiChing-Hua LiHengne LiJiuzhao LiKechen LiLanxing LiManshu LiPeilian LiPei-Rong LiQinze LiShiyang LiTiange LiTianqi LiYanru LiYiming LiYujie LiZhengchen LianQiming LiangXixin LiangSimone LibralonChuangxin LinTai-Hua LinRolf LindnerHenry James LintonRoman LitvinovDuanqing LiuFrank Xiangyu LiuGuoming LiuKai LiuShuaiyi LiuWeijie LiuYiming LiuYing LiuYiwei LiuGustavo Alejandro Loachamin OrdonezAniol Lobo SalviaAngelo LoiThomas LongJose LopesAlbert Lopez HuertasSaúl López SoliñoQiuchan LuChiara LucarelliDonatella LucchesiMiriam Lucio MartinezYiheng LuoAnna LupatoEleonora LuppiKate LynchXiao-Rui LyuGe MaSerena MaccoliniFrederic MachefertFlorin MaciucBridget MackInnes MackayLauren Grace MackeyLakshan Ram Madhan MohanMarcus Jonathan MaduraiDaniel MagdalinskiDmitrii MaisuzenkoJakub Jacek MalczewskiSneha MaldeLorenzo MalentaccaAlexander MalininTimofei MaltsevGiulia MancaGiampiero MancinelliChiara MancusoRafel Manera EscaleroFederico ManganellaDaniele ManuzziDaniele MarangottoJean François MarchandRadoslav MarchevskiUmberto MarconiEdoardo MarianiSaverio MarianiCarla Marin BenitoJörg MarksAlexander Mclean MarshallLucas MartelGabriele MartelliGiuseppe MartellottiLoris MartinazzoliMaurizio MartinelliDaniel Guillermo Martinez GomezDiego Martinez SantosFernando Martinez VidalAlexia Martorell GranollersAndré MassafferriRosen MatevAbhijit MathadViacheslav MatiuninClara MatteuzziKara Renee MattioliAndrea MauriEmilie MauriceJoan MauricioPierre Paul Louis MayencourtJose Mazorra de CosMichal MazurekMichael MccannTamaki Holly McgrathNiall Thomas MchughAndrew McnabRonan McnultyBrian MeadowsGerwin MeierDmytro MelnychukFanjie MengMarcel MerkAndrea MerliLucas Meyer GarciaDexing MiaoHan MiaoMikhail MikhasenkoDiego Alejandro MilanesAlessandro MinottiElisa MinucciTristan MirallesBiljana MitreskaDominik Stefan MitzelAtanu ModakLeandra MoeserRizwaan Adeeb MohammedRazvan-Daniel MoiseEsteban Felipe Molina CardenasTitus MombächerMatthew David MonkStephane MonteilAngel Morcillo GomezGianfranco MorelloMichael Joseph MorelloMaurice Pierre MorgenthalerJakub MoronWouter MorrenAdam Benjamin MorrisAndrew George MorrisRaymond MountainHongjie MuZeqing MuEmir MuhammadFranz MuheimMick MulderKatharina MüllerFederico Muñoz-RojasRebecca MurtaViktor MytrochenkoParas NaikTatsuya NakadaRaja NandakumarTara NanutIrina NastevaMatthew NeedhamEvgeniia NekrasovaNicola NeriSebastian NeubertNiko NeufeldPetr NeustroevJanina NicoliniDavide NicotraElisabeth Maria NielNikolay NikitinQile NiuPedro NogarolliPiet NoggaCamille NormandJulio Novoa FernandezGabriel Matthew NowakCynthia NunezHavva Hasret NurAgnieszka Oblakowska-MuchaVladimir ObraztsovThomas OeserArtem OkhotnikovOleksandr OkhrimenkoRudolf OldemanFederica OlivaErnest Olivart PinoMicol OloccoGerco OnderwaterRyunosuke Hugo O'NeilDonata OsthuesJuan Martin Otalora GoicocheaPatrick OwenMaria Aranzazu OyangurenOzlem OzcelikFrancesco PaciollaAdam PadeeKlaas Ole PadekenBhagyashree PagareTommaso PajeroAntimo PalanoMatteo 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ZhangYanxi ZhangYuge ZhangZhicai ZhangYa ZhaoAlexey ZhelezovShuang ZhengXutao ZhengYangheng ZhengTianwen ZhouXiaokang ZhouYixiong ZhouValeriia ZhovkovskaLinxuan ZhuXianglei ZhuXiaoyu ZhuYibo ZhuValery ZhukovJiahui ZhuoQuan ZouDavide ZulianiGianluca Zunica
• Organismes : Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire Leprince-Ringuet Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire Leprince-Ringuet Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie

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Résumé : A search is presented for axion-like particles (ALPs) with masses between 4.9 and 19.4 GeV decaying to a pair of photons, using proton-proton collisions collected with the LHCb detector during 2018 at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 2.1 fb$^{-1}$. The same strategy and sample is used to search for the decays of the $B^0_s$, $B^0$ and $η_b$ mesons into photon pairs. No significant excess is found. Upper limits on the photon-pair branching fraction times the cross-section of ALP production are determined as a function of the ALP mass. Limits on the branching fractions of the beauty states are determined to be $\mathcal{B}(B^0_s\toγγ)<2.7\times10^{-5}$, $\mathcal{B}(B^0\toγγ)<0.83\times10^{-5}$, and $ σ(pp\toη_b X)\times\mathcal{B}(η_b\toγγ)<765\,\text{pb}$ at 95 % confidence level.

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Source

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 29/07/2025
• Auteurs : Vladimir ChekhovskyAram HayrapetyanVladimir MakarenkoArmen TumasyanWolfgang AdamJanik Walter AndrejkovicLisa BenatoThomas BergauerKonstantinos DamanakisMarko DragicevicCristina GiordanoPriya Sajid HussainManfred JeitlerNatascha KrammerAng LiDietrich LikoIvan MikulecJochen SchieckRobert SchöfbeckDennis SchwarzMangesh SonawaneWolfgang WaltenbergerClaudia-Elisabeth WulzTahys JanssenHyejin KwonThomas van LaerPierre van MechelenJas BierkensNordin BreugelmansJorgen d'HondtSoumya DansanaAlexandre de MoorMartin DelcourtFelix HeyenYanwen HongSteven LowetteInna MakarenkoDenise MüllerStefaan TavernierMichael TytgatGerrit Patrick van OnsemSenne van PutteDavid VanneromBugra BilinBarbara ClerbauxAloke Kumar DasIsabelle de BruynGilles de LentdeckerHugues EvardLaurent FavartParaskevas GianneiosAli KhalilzadehFakhri Alam KhanAndrea MalaraMuhammad Aamir ShahzadLaurent ThomasMax Vanden BemdenCatherine Vander VeldePascal VanlaerFengwangdong ZhangMaarten de CoenDidar DoburGul GokbulutJoscha KnolleLuka LambrechtDavid MarckxKirill SkovpenNiels van den BosscheJan van der LindenJules VandenbroeckLiam WezenbeekSamuel BeinAnna BeneckeAgni BethaniGiacomo BrunoAlessandra CappatiJerome de Favereau de JeneretChristophe DelaereAndrea GiammancoAhmet Oguz GuzelSandhya JainVincent LemaitreJindrich LidrychPaola MastrapasquaSemra TurkcaparGilvan AlvesEduardo CoelhoGilson Correia SilvaCarsten HenselThales Menezes de OliveiraClemencia Mora HerreraPatricia Rebello TelesMariana SoeiroEdmilson José Tonelli ManganoteAntonio Vilela PereiraWalter Luiz Aldá JúniorMapse Barroso Ferreira FilhoHelena Brandao MalbouissonWagner CarvalhoJose ChinellatoEliza Melo da CostaGustavo Gil da SilveiraDilson de Jesus DamiaoSandro Fonseca de SouzaRaphael Gomes de SouzaSilas JesusTulio Laux KuhnMatheus MacedoKevin Mota AmariloLuiz MundimHelio NogimaJoao Pedro PinheiroAlberto SantoroAndre SznajderMauricio ThielCesar Augusto BernardesLuigi CalligarisThiago TomeiEduardo de Moraes GregoresIsabela Maietto SilverioPedro G MercadanteSergio F NovaesBreno OrzariSandra PadulaValerie ScheurerAleksandar AleksandrovGeorgy AntchevRoumyana HadjiiskaPlamen IaydjievMilena MishevaMariana ShopovaGeorgi SultanovAnton DimitrovLeander LitovBorislav PavlovPeicho PetkovAnton PetrovElton ShumkaSumit KeshriDavid Nicolas Laroze NavarreteShalini ThakurTongguang ChengQianying GuoTahir JavaidLi YuanZhen HuZhengchen LiangJinfeng LiuGuo-Ming ChenHe-Sheng ChenMingshui ChenQingfeng HouFabio IemmiChun-Hua JiangAnshul KapoorHongbo LiaoZhenan LiuRamkrishna SharmaJia-Ning SongJunquan TaoChu WangJin WangHuaqiao ZhangJingzhou ZhaoAntonis AgapitosYong BanAlexandra Carvalho Antunes de OliveiraSen DengBotao GuoChuqiao JiangAndrew LevinCongqiao LiQiang LiYajun MaoSitian QianSi-Jin QianXuelong QinXiaohu SunDayong WangHeng YangYuzhe ZhaoChen ZhouShuai YangZhengyun YouKhawla JaffelNan LuGerry BauerBolin LiHui WangKai YiJingqing ZhangYuji LiZhen LinChenfeng LuMeng XiaoCarlos AvilaDiego Andres Barbosa TrujilloAndrés CabreraCarlos 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Résumé : A measurement of the angular structure of jets containing a prompt D$^0$ meson and of inclusive jets in proton-proton collisions at the LHC at a center-of-mass energy of 5.02 TeV is presented. The data corresponding to an integrated luminosity of 301 pb$^{-1}$ were collected by the CMS experiment in 2017. Two jet grooming algorithms, late-$k_\mathrm{T}$ and soft drop, are used to study the intrajet radiation pattern using iterative Cambridge$-$Aachen declustering. The splitting-angle distributions of jets with transverse momentum ($p_\mathrm{T}$) of around 100 GeV, obtained with these two algorithms, show that there is a shift of the distribution for jets containing a prompt D$^0$ meson with respect to inclusive jets. The shift observed in the late-$k_\mathrm{T}$ grooming approach is consistent with the dead-cone effect, whereas the shift for splittings selected with the soft-drop algorithm appears to be dominated by gluon splitting to charm quark-antiquark pairs. The measured distributions are corrected to the particle level and can be used to constrain model predictions for the substructure of high-$p_\mathrm{T}$ charm quark jets.

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