Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 11/03/2008
• Auteurs : Rodolphe AntyMonsef DahmanAntonio IannelliPhilippe GualAline Staccini-MyxImed Ben AmorNathalie LucianiMarie-Christine Saint-PaulPierre-Michel HuetJean-Louis SadoulSurjit Kaila S SraiRobert UnwinJean GugenheimYannick Le Marchand-BrustelAlbert TranSoumeya BekriSurjit Kaila S. Srai
• Organismes : Centre méditerranéen de médecine moléculaire Centre méditerranéen de médecine moléculaire Centre méditerranéen de médecine moléculaire Ecole Polytechnice Universitaire de Nice Matière et Systèmes Complexes Pôle Digestif Pôle Digestif Service d'Endocrinologie Royal Free and University College Medical School Centre Hospitalier Universitaire de Nice Signalisation moléculaire et obésité Centre méditerranéen de médecine moléculaire Centre Hospitalier Universitaire de Nice Laboratoire de biochimie générale [Rouen]
• Publié dans Obesity Surgery le 01/11/2020

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Résumé : Obesity is associated with a chronic and low-grade inflammation which may cause hypoferremia as seen in patients with chronic inflammatory diseases. The aim of the present study was to investigate the relationship between iron status and markers of inflammation in morbidly obese women and the effect of bariatric surgery.

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• Type de publi. : Communication dans un congrès
• Date de publi. : 11/03/2008
• Auteurs : Wigneron J.-P.Yann H. KerrKauzar Saleh ContellPhilippe RichaumePatricia de RosnayMaria Jose EscorihuelaJean-Christophe CalvetAurelio CanoAndré ChanzyFrançois DemontouxJennifer GrantMassimo GuglielmettiPaolo FerrazzoliHeather LawrenceErnesto Lopez-BaezaArnaud MialonThierry PellarinChristoph RüdigerGilles RuffiéMike SchwankNiels SkouPhilippe WaldteufelMichael BergerSteven Delwart
• Organismes : Écologie fonctionnelle et physique de l'environnement Centre d'études spatiales de la biosphère Centre d'études spatiales de la biosphère Centre d'études spatiales de la biosphère European Centre for Medium-Range Weather Forecasts Centre d'études spatiales de la biosphère Centre national de recherches météorologiques Universitat de València = University of Valencia = Universidade de Valencia Environnement Méditerranéen et Modélisation des Agro-Hydrosystèmes Laboratoire de l'intégration, du matériau au système Vrije Universiteit Amsterdam [Amsterdam] Eidgenössische Technische Hochschule - Swiss Federal Institute of Technology [Zürich] Università degli Studi di Roma Tor Vergata [Roma, Italia] = University of Rome Tor Vergata [Rome, Italy] = Université de Rome Tor Vergata [Rome, Italie] Écologie fonctionnelle et physique de l'environnement Laboratoire de l'intégration, du matériau au système Universitat de València = University of Valencia = Universidade de Valencia Centre d'études spatiales de la biosphère Centre National de la Recherche Scientifique Centre national de recherches météorologiques Laboratoire de l'intégration, du matériau au système Institute of Terrestrial Ecosystems National Space Institute [Lyngby] Service d'aéronomie Agence Spatiale Européenne = European Space Agency Agence Spatiale Européenne = European Space Agency

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Fichiers liés : Wigneron-microrad08-PPT-Parameterisation_2.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 10/03/2008
• Auteurs : Kauzar Saleh ContellYann H. KerrGilles BouletMaria Jose EscorihuelaPhilippe MaisongrandePhilippe RichaumePatricia de RosnayWigneron J.-P.Ernesto Lopez-BaezaJennifer GrantSteven DelwartMichael BergerRocco PancieraJeff Walker
• Organismes : Department of Geography [Cambridge, UK] Centre d'études spatiales de la biosphère Centre d'études spatiales de la biosphère Centre d'études spatiales de la biosphère Centre National d’Etudes Spatiales Centre d'études spatiales de la biosphère Centre d'études spatiales de la biosphère Écologie fonctionnelle et physique de l'environnement Universitat de València = University of Valencia = Universidade de Valencia Vrije Universiteit Amsterdam [Amsterdam] European Space Research and Technology Centre Agence Spatiale Européenne = European Space Agency University of Melbourne University of Melbourne

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Résumé : The ESA CoSMOS study aims at performing the first validation of the SMOS Soil Moisture Level 2algorithm using real data. The validation relies on data acquired during the CoSMOS/NAFE campaign in the Goulburn River Catchment (Southeast Australia) in 2005. The CoSMOS/ NAFE airborne campaign involved two L-band radiometers, EMIRAD (full- pol, bi-angular) and PLMR (dual-pol, multi-angular), and provided L- band data at different resolutions for six weeks.Intensive ground sampling was carried out too to provide measurements of all the surface parameters required by the soil moisture retrieval algorithm. This communication presents the main outcomes of the study. The focus is threefold:i) how do simulations of the surface brightness temperature and soil moisture retrievals perform using the ^Ñdefault^Ò L2 algorithm over homogenous an heterogeneous surfaces? Ii) what recommendations can be made in terms of fine-tuning of the microwave model used by the SMOSretrieval algorithm (soil model, vegetation model, litter model), and iii) how does the retrieved soil moisture at the scale of a SMOS pixel compare to ground measurements of soil moisture across the catchment? These questions are addressed in the ESA CoSMOS study, which makes a comprehensive data set available for validation of the SMOS Level 2 algorithm, and is currently at the phase of performing the forward model simulations and soil moisture retrievals.

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Fichiers liés : Saleh-Microrad2008_1.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 10/03/2008
• Auteurs : Frédéric MoynierQing-Zhu YinPhilippe GilletPierre BeckTristan FerroirJean-Alix BarratFrancis Albarède
• Organismes : McDonnell Center for Space Sciences Department of Earth and Planetary Sciences [St Louis] Department of Geology [Davis] Department of Geology [Davis] Laboratoire de Sciences de la Terre Laboratoire de Planétologie de Grenoble Laboratoire de Sciences de la Terre Institut d'étude de la mer Laboratoire de Sciences de la Terre

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Résumé : We measured the Cr and Zn stable isotope compositions of nine ureilite samples. Both Cr and Zn isotopic ratios are negatively correlated with their respective concentrations. These results may reflect isotopic fractionations during volatile loss.

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• Type de publi. : Communication dans un congrès
• Date de publi. : 07/03/2008
• Auteurs : Rabie Ben AtitallahPhilippe MarquetÉric PielSamy MeftaliSmail NiarAnne EtienJean-Luc DekeyserPierre Boulet
• Organismes : Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Automatique, de Mécanique et d'Informatique industrielles et Humaines - UMR 8201 Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time

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• Type de publi. : Article dans une revue
• Date de publi. : 06/03/2008
• Auteurs : Philippe PoncetRoland HildebrandGeorges-Henri CottetPetros Koumoutsakos
• Organismes : Mathématiques pour l'Industrie et la Physique Calculs Algébriques et Systèmes Dynamiques Equations aux Dérivées Partielles Computational Science and Engineering Laboratory
• Publié dans Journal of Fluid Mechanics le 26/10/2020

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Résumé : We report high drag reduction in Direct Numerical Simulations of controled flows past circular cylinders at Reynolds numbers of 300 and 1000. The flow is controlled by the azimuthal component of the tangential velocity of the cylinder surface. Starting from a spanwise uniform velocity profile that leads to high drag reduction, the optimization procedure identifies, for the same energy input, spanwise varying velocity profiles that lead to higher drag reduction. The three dimensional variations of the velocity field, corresponding to the modes A and B of three dimensional wake instabilities, are largely responsible for this drag reduction. The spanwise, wall velocity variations introduce streamwise vortex braids in the wake that are responsible for reducing the drag induced by the primary spanwise vortices shed by the cylinder. The results demonstrate that extending two dimensional controllers to three-dimensional flows is not optimal as three dimensional control strategies can lead efficiently to higher drag reduction.

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Fichiers liés : JFM-07-FT-0401.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 04/03/2008
• Auteurs : Philippe MenaschéOttavio AlfieriStefan JanssensWilliam MckennaHermann ReichenspurnerLudovic TrinquartJean-Thomas VilquinJean-Pierre MarolleauBarbara SeymourJérôme LargheroStephen LakeGilles ChatellierScott SolomonMichel DesnosAlbert Hagège
• Organismes : Centre de recherche en Myologie – U974 SU-INSERM
• Publié dans Circulation le 29/10/2020

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Résumé : Background— Phase I clinical studies have demonstrated the feasibility of implanting autologous skeletal myoblasts in postinfarction scars. However, they have failed to determine whether this procedure was functionally effective and arrhythmogenic. Methods and Results— This multicenter, randomized, placebo-controlled, double-blind study included patients with left ventricular (LV) dysfunction (ejection fraction ≤35%), myocardial infarction, and indication for coronary surgery. Each patient received either cells grown from a skeletal muscle biopsy or a placebo solution injected in and around the scar. All patients received an implantable cardioverter-defibrillator. The primary efficacy end points were the 6-month changes in global and regional LV function assessed by echocardiography. The safety end points comprised a composite index of major cardiac adverse events and ventricular arrhythmias. Ninety-seven patients received myoblasts (400 or 800 million; n=33 and n=34, respectively) or the placebo (n=30). Myoblast transfer did not improve regional or global LV function beyond that seen in control patients. The absolute change in ejection fraction (median [interquartile range]) between 6 months and baseline was 4.4% (0.2; 7.3), 3.4% (−0.3; 12.4), and 5.2% (−4.4; 11.0) in the placebo, low-dose, and high-dose groups, respectively ( P =0.95). However, the high-dose cell group demonstrated a significant decrease in LV volumes compared with the placebo group. Despite a higher number of arrhythmic events in the myoblast-treated patients, the 6-month rates of major cardiac adverse events and of ventricular arrhythmias did not differ significantly between the pooled treatment and placebo groups. Conclusions— Myoblast injections combined with coronary surgery in patients with depressed LV function failed to improve echocardiographic heart function. The increased number of early postoperative arrhythmic events after myoblast transplantation, as well as the capability of high-dose injections to revert LV remodeling, warrants further investigation.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/03/2008
• Auteurs : Dinah ParkerVincent DupuisFrançois LadieuJean-Philippe BouchaudDubois EmmanuelleRégine PerzynskiEric Vincent
• Organismes : Service de physique de l'état condensé University of Oxford Liquides Ioniques et Interfaces Chargées Service de physique de l'état condensé Service de physique de l'état condensé Liquides Ioniques et Interfaces Chargées Liquides Ioniques et Interfaces Chargées Service de physique de l'état condensé
• Publié dans Physical Review B: Condensed Matter and Materials Physics (1998-2015) le 02/11/2020

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Résumé : In this paper we investigate the superspin glass behavior of a concentrated assembly of interacting maghemite nanoparticles and compare it to that of canonical atomic spin glass systems. ac versus temperature and frequency measurements show evidence of a superspin glass transition taking place at low temperature. In order to fully characterize the superspin glass phase, the aging behavior of both the thermo-remanent magnetization (TRM) and ac susceptibility has been investigated. It is shown that the scaling laws obeyed by superspin glasses and atomic spin glasses are essentially the same, after subtraction of a superparamagnetic contribution from the superspin glass response functions. Finally, we discuss a possible origin of this superparamagnetic contribution in terms of dilute spin glass models.

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Fichiers liés : SGNanoparticles_ParkerDupuis_Feb08.pdf

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• Type de publi. : Ouvrage (y compris édition critique et traduction)
• Date de publi. : 01/03/2008
• Auteurs : Philippe SabouraultJean-François SidanerHormoz ModaressiJean-Louis DurvilleMarc WecksteinJean-Luc BerenguerMartine AufeuvreJean VirieuxJean-Pierre TouretPascal BernardPierre-Yves Bard
• Organismes : Direction Générale de la Prévention des Risques Bureau de Recherches Géologiques et Minières Bureau de Recherches Géologiques et Minières Géoazur Département de sismologie Laboratoire de Géophysique Interne et Tectonophysique

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• Type de publi. : Article dans une revue
• Date de publi. : 01/03/2008
• Auteurs : Tristan CenierCorine AmatPhilippe LitaudonSamuel GarciaPierre Lafaye de MicheauxBenoit LiquetStéphane G. RouxNathalie Buonviso
• Organismes : Neurosciences Sensorielles Comportement Cognition Neurosciences Sensorielles Comportement Cognition Laboratoire d'analyse et d'architecture des systèmes Neurosciences Sensorielles Comportement Cognition Neurosciences Sensorielles Comportement Cognition Stress Cellulaire Croissance cellulaire, réparation et régénération tissulaires Statistique Appliquée et de Géométrie Aléatoire de Grenoble Grenoble Institut des Neurosciences Institut de Santé Publique, d'Epidémiologie et de Développement Laboratoire de Statistiques et Analyse des Données Biostatistique Epidémiologie et Biostatistique [Bordeaux] Laboratoire de Physique de l'ENS Lyon Neurosciences Sensorielles Comportement Cognition
• Publié dans European Journal of Neuroscience le 22/10/2020

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Résumé : A central question in chemical senses is the way that odorant molecules are represented in the brain. To date, many studies, when taken together, suggest that structural features of the molecules are represented through a spatio-temporal pattern of activation in the olfactory bulb (OB), in both glomerular and mitral cell layers. Mitral/tufted cells interact with a large population of inhibitory interneurons resulting in a temporal patterning of bulbar local field potential (LFP) activity. We investigated the possibility that molecular features could determine the temporal pattern of LFP oscillatory activity in the OB. For this purpose, we recorded the LFPs in the OB of urethane-anesthetized, freely breathing rats in response to series of aliphatic odorants varying subtly in carbon-chain length or functional group. In concordance with our previous reports, we found that odors evoked oscillatory activity in the LFP signal in both the beta and gamma frequency bands. Analysis of LFP oscillations revealed that, although molecular features have almost no influence on the intrinsic characteristics of LFP oscillations, they influence the temporal patterning of bulbar oscillations. Alcohol family odors rarely evoke gamma oscillations, whereas ester family odors rather induce oscillatory patterns showing beta/gamma alternation. Moreover, for molecules with the same functional group, the probability of gamma occurrence is correlated to the vapor pressure of the odor. The significance of the relation between odorant features and oscillatory regimes along with their functional relevance are discussed.

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