Philippe JEAN-PIERRE

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Maëlenn GuerchetDismand Stephan HouinatoMoussiliou Noël ParaïsoNicolas von AhsenPhilippe NubukpoMarkus OttoJean-Pierre ClémentPierre-Marie PreuxJean-François Dartigues
• Organismes : Neuroépidémiologie Tropicale et Comparée Neuroépidémiologie Tropicale et Comparée Unité d'Enseignement et de Recherche de Neurologie Neuroépidémiologie Tropicale et Comparée Neuroépidémiologie Tropicale et Comparée Hôpital Psychiatrique La Valette Centre de Mémoire de Ressources et de Recherches [Limoges] Neuroépidémiologie Tropicale et Comparée Centre de Mémoire de Ressources et de Recherches [Limoges] Service de Psychiatrie [CHU Limoges] Neuroépidémiologie Tropicale et Comparée Service de l'Information Médicale et de l'Évaluation [CHU Limoges] Laboratoire de Biostatistique et d'Informatique Médicale Epidémiologie et Biostatistique [Bordeaux]
• Publié dans Dementia and Geriatric Cognitive Disorders le 01/11/2020

---

Résumé : BACKGROUND/AIMS: Dementia is increasing as a priority public health problem because of the ageing of the world population. Our goal was to estimate dementia and cognitive impairment prevalence in an elderly population of rural Benin. METHODS: In a door-to-door survey, elderly people aged 65 years and above were screened using the Community Screening Interview for Dementia and the Five-Word Test. RESULTS: The prevalence of cognitive impairment was 10.4% and that of dementia was 2.6%. Age, current depressive disorder and absence of the APOE epsilon2 allele were significantly associated with cognitive impairment. CONCLUSION: Prevalence of dementia and cognitive impairment appears to be lower in this study than in developed countries.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Mathieu SchusterPhilippe DuringerJean-François GhienneClaude RoquinPierre SepulchreAbderamane MoussaA.-E. LebatardHassan Taisso MackayeAndossa LikiusPatrick VignaudMichel Brunet
• Organismes : Institut de physique du globe de Strasbourg Institut de physique du globe de Strasbourg Institut de physique du globe de Strasbourg Institut de physique du globe de Strasbourg Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] Modélisation du climat Institut de physique du globe de Strasbourg Centre Européen de Recherche et d'Enseignement des Géosciences de l'Environnement Université de N'Djaména Université de N'Djaména Laboratoire de paléontologie, évolution, paléoécosystèmes, paléoprimatologie [UMR 7262] Institut international de paléoprimatologie, paléontologie humaine : Évolution et paléoenvironnement [UMR 6046] Collège de France - Chaire Paléontologie Humaine
• Publié dans Comptes Rendus. Géoscience le 29/07/2021

---

Résumé : Since the mid 1990s, the Mission paléoanthropologique francotchadienne (MPFT) conducts yearly paleontological field investigations of the Miocene-Pliocene of the Chad Basin. This article synthesizes some of the results of the MPFT, with focus on the Chad Basin development during the Neogene. We propose an overview of the depositional paleoenvironments of this part of Africa at different scales of time and space, based on a multidisciplinary approach (sedimentary geology, geomorphology, geophysic, numerical simulations and geochronology). The Miocene-Pliocene paleoenvironments are examined through the sedimentary archives of the early hominids levels and the Holocene Lake Mega-Chad episode illustrates the last major paleoenvironmental change in this area. The sedimentary record of the Chad Basin since the Late Miocene can be schematized as the result of recurrent interactions from lake to desert environments.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Laurent LardonArnaud HéliasBruno SialveJean-Philippe SteyerOlivier Bernard
• Organismes : Laboratoire de Biotechnologie de l'Environnement [Narbonne] Laboratoire de Biotechnologie de l'Environnement [Narbonne] Institut national d’études supérieures agronomiques de Montpellier Modeling and control of renewable resources Laboratoire de Biotechnologie de l'Environnement [Narbonne] Modeling and control of renewable resources
• Publié dans Environmental Science and Technology le 24/10/2020

---

Résumé : This paper provides an analysis of the potential environmental impacts of biodiesel production from microalgae. High production yields of microalgae have called forth interest of economic and scientific actors but it is still unclear whether the production of biodiesel is environmentally interesting and which transformation steps need further adjustment and optimization. A comparative LCA study of a virtual facility has been undertaken to assess the energetic balance and the potential environmental impacts of the whole process chain, from the biomass production to the biodiesel combustion. Two different culture conditions, nominal fertilizing or nitrogen starvation, as well as two different extraction options, dry or wet extraction, have been tested. The best scenario has been compared to first generation biodiesel and oil diesel. The outcome confirms the potential of microalgae as an energy source but highlights the imperative necessity of decreasing the energy and fertilizer consumption. Therefore control of nitrogen stress during the culture and optimization of wet extraction seem to be valuable options. This study also emphasizes the potential of anaerobic digestion of oilcakes as a way to reduce external energy demand and to recycle a part of the mineral fertilizers.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Philippe LericheFlavia PironEmilie RipaudPierre FrèreMagali AllainJean Roncali
• Organismes : MOLTECH-Anjou MOLTECH-Anjou MOLTECH-Anjou MOLTECH-Anjou
• Publié dans Tetrahedron Letters le 22/10/2020

---

Résumé :

Star-shaped molecules consisting of short-chain oligothiophenes attached onto an electron acceptor triazine core have been synthesized. Results of the analysis of the electronic properties of these compounds by UV–vis spectroscopy and cyclic voltammetry are used to discuss the impact of the electron-withdrawing node on the properties of the compounds. The electrochemical oxidation of some of these systems into the corresponding electroactive polymers is briefly discussed.

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2009
• Auteurs : Philippe LerichePierre FrèrePhilippe BlanchardAntonio CravinoJean Roncali
• Organismes : MOLTECH-Anjou MOLTECH-Anjou MOLTECH-Anjou MOLTECH-Anjou MOLTECH-Anjou

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Akram IdaniJean--Louis BoulangerLaurent Philippe
• Organismes : Validation de Systèmes, Composants et Objets logiciels Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174)
• Publié dans International Journal of Computers and their Applications (IJCA), Special Issue on the Application of Computer Technology to Public Safety and Law Enforcement le 06/11/2014

---

Résumé : no abstract

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Philippe StempfléT. DjilaliRichard Kouitat NjiwaMarthe RousseauEvelyne LopezXavier Bourrat
• Organismes : Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) Institut Jean Lamour Ecole Nationale Supérieure des Mines de Nancy Biologie des organismes marins et écosystèmes Biologie des organismes marins et écosystèmes Institut des Sciences de la Terre d'Orléans
• Publié dans Tribology Letters le 25/10/2020

---

Résumé : Sheet nacre is a natural biocomposite with a multiscale structure including a mineral phase of calcium carbonate (97 wt.%) and two organic matrices (3 wt.%). The mineral phase is constituted by an arrangement of CaCO3 biocrystal nanograins (ca 40 nm in size) drowned in an ‘‘intracrystalline'' organic matrix (4 nm thick) in order to form a microsized flat organomineral aragonite platelet. These platelets are themselves surrounded by an ‘‘intercrystalline'' organic matrix (40 nm thick) building up a very tough materials. This microarchitecture referred to as ‘‘bricks and mortar'' nacre structure, is mainly studied for the creation of new organic/inorganic hybrid materials. Currently, only little is known about the nacre mechanical behaviour under dynamical loading and more particularly under tribological conditions which involve shocks and thermal effects simultaneously. This paper brings out the thermal-induced damage mechanisms effect on the wear of sheet nacre by the assessment of the thermal component of the friction with a scanning thermal microscope. Results reveal that the mean contact pressure is the main driving force involved in the degradation of the organic constituents. For the lowest mean contact pressure (\0.4 MPa), wear is rather weak because the friction-induced thermal component is not sufficient for degrading the organic matrices. In contrast, beyond 0.4 MPa, the friction-induced contact temperature rises up over the melting point of the organic matrices, and may even reach the temperature of the aragonite– calcite phase transformation increasing dramatically the wear of sheet nacre.

---

Fichiers liés : 2009_Stempfle_etal_TribologyLetters_version_hal.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Margot FournierJérémie VitteJérôme GarrigueDominique LanguiJean-Philippe DullinFrançoise SauriniNaïma HanounFernando Perez-DiazFabien CornilleauChantal JoubertHéctor Ardila-OsorioSabine TraverRené DuchateauCécile Goujet-ZalcKaterina PaleologouHilal A LashuelChristian HaassCharles DuyckaertsCharles Cohen-SalmonPhilipp J KahleMichel HamonAlexis BriceOlga Corti
• Organismes : Neurogenetique Moleculaire Mécanismes adaptatifs : des organismes aux communautés Institut de médecine moléculaire de Rangueil Vulnérabilité Adaptation et Psychopathologie CHU Pitié-Salpêtrière [AP-HP] Centre de Recherche de l'Institut du Cerveau et de la Moelle épinière CHU Pitié-Salpêtrière [AP-HP] CHU Pitié-Salpêtrière [AP-HP] Neurologie et thérapeutique expérimentale
• Publié dans PLoS ONE le 25/10/2020

---

Résumé : In synucleinopathies, including Parkinson's disease, partially ubiquitylated alpha-synuclein species phosphorylated on serine 129 (P(S129)-alpha-synuclein) accumulate abnormally. Parkin, an ubiquitin-protein ligase that is dysfunctional in autosomal recessive parkinsonism, protects against alpha-synuclein-mediated toxicity in various models.We analyzed the effects of Parkin deficiency in a mouse model of synucleinopathy to explore the possibility that Parkin and alpha-synuclein act in the same biochemical pathway. Whether or not Parkin was present, these mice developed an age-dependent neurodegenerative disorder preceded by a progressive decline in performance in tasks predictive of sensorimotor dysfunction. The symptoms were accompanied by the deposition of P(S129)-alpha-synuclein but not P(S87)-alpha-synuclein in neuronal cell bodies and neuritic processes throughout the brainstem and the spinal cord; activation of caspase 9 was observed in 5% of the P(S129)-alpha-synuclein-positive neurons. As in Lewy bodies, ubiquitin-immunoreactivity, albeit less abundant, was invariably co-localized with P(S129)-alpha-synuclein. During late disease stages, the disease-specific neuropathological features revealed by ubiquitin- and P(S129)-alpha-synuclein-specific antibodies were similar in mice with or without Parkin. However, the proportion of P(S129)-alpha-synuclein-immunoreactive neuronal cell bodies and neurites co-stained for ubiquitin was lower in the absence than in the presence of Parkin, suggesting less advanced synucleinopathy. Moreover, sensorimotor impairment and manifestation of the neurodegenerative phenotype due to overproduction of human alpha-synuclein were significantly delayed in Parkin-deficient mice.These findings raise the possibility that effective compensatory mechanisms modulate the phenotypic expression of disease in parkin-related parkinsonism.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Mireille FlouzatPierre BettinelliPascal WillisJean‐philippe AvouacThierry HéritierUmesh Gautam
• Organismes : Centre d'Études de Limeil-Valenton Centre d'Études de Limeil-Valenton Institut de Physique du Globe de Paris Centre d'Études de Limeil-Valenton
• Publié dans Geophysical Journal International le 25/10/2020

---

Résumé : Geodetic time-series from continuous GPS (cGPS) and 1 DORIS stations across the Himalaya of central Nepal show strong seasonal fluctuations observed on the horizontal and vertical components. Because the fluctuations determined at the different stations have similar phase but different amplitudes, these observations would imply that the secular shortening across the range is modulated by a seasonal strain. Given the geographic and climatic setting, there is however a possibility that the GPS positions be biased by tropospheric effects. We process these data using two different software packages and two different analysis strategies. Our analysis shows evidence for 1-strong seasonal fluctuation of zenithal delays consistent with in situ meteorological data and two strong horizontal tropospheric gradients in particular in the EW direction, that is, parallel to the mountain front at Gumba, also detected in DORIS results. We show that the tropospheric effects cannot however be the source of the observed seasonality of horizontal strain. This study supports the view that the seasonal strain in the Himalaya is real and probably driven by seasonal surface load variations. Our study adds support to the view that seasonal variations of seismicity in the Himalaya reflects seasonal variations of geodetic strain.

---

Fichiers liés : 178-3-1246.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2009
• Auteurs : Jérôme VialardJean-Philippe DuvelMichael J. McphadenPascale Bouruet-AubertotBrian WardErica KeyDenis BourrasR. WellerP. J. MinnettAlain WeillChristophe CassouLaurence EymardT. FristedtClaude BasdevantYves DandonneauOlaf DuteilTakeshi IzumoClément de Boyer MontégutSébastien MassonFrancis MarsacChristophe MenkesSean C. Kennan
• Organismes : Laboratoire d'Océanographie et du Climat : Expérimentations et Approches Numériques Laboratoire de Météorologie Dynamique (UMR 8539) Laboratoire d'Océanographie et du Climat : Expérimentations et Approches Numériques ESTER - LATMOS ESTER - LATMOS Centre Européen de Recherche et de Formation Avancée en Calcul Scientifique Laboratoire d'Océanographie et du Climat : Expérimentations et Approches Numériques Laboratoire de Météorologie Dynamique (UMR 8539) Laboratoire d'Océanographie et du Climat : Expérimentations et Approches Numériques Laboratoire d'Océanographie et du Climat : Expérimentations et Approches Numériques Laboratoire d'Océanographie et du Climat : Expérimentations et Approches Numériques Laboratoire d'Océanographie et du Climat : Expérimentations et Approches Numériques Thons tropicaux et écosystèmes pélagiques : taxies, interactions et stratégies d'exploitation Laboratoire d'Océanographie et du Climat : Expérimentations et Approches Numériques
• Publié dans Bulletin of the American Meteorological Society le 26/10/2020

---

Fichiers liés : %5B15200477%20-%20Bulletin%20of%20the%20American%20Meteorological%20Society%5D%20Supplement%20to%20Cirene%3A%20Air%E2%80%94Sea%20Interactions%20in%20the%20Seychelles%E2%80%94Chagos%20Thermocline%20Ridge%20Region.pdf

---

Source