Philippe JEAN-PIERRE

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• Type de publi. : Communication dans un congrès
• Date de publi. : 28/08/2007
• Auteurs : François BermondYves CairePhilippe VezinJean-Pierre Verriest
• Organismes : Laboratoire de Biomécanique et Mécanique des Chocs Laboratoire de Biomécanique et Mécanique des Chocs Laboratoire de Biomécanique et Mécanique des Chocs Laboratoire de Biomécanique et Mécanique des Chocs

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Résumé : The WorldSID program was set up to develop a new, worldwide acceptable, advanced technology, side impact crash test dummy for improved assessment of injury risk to car occupants in lateral collisions. Following the release of the mid-sized male WorldSID, the development of the small female WorldSID dummy was initiate under the European Commission Integrated Project 'APROSYS' (Been et al. 2006, 2007). The main specifications and requirements of the new dummy have been defined in terms of anthropometry, biomechanical response and instrumentation capabilities in general and per body segment, by the APROSYS WP5.2 team. The prototype was subjected to an extensive set of biomechanical, durability and sensitivity tests using, pendulum, linear guided mass impactor and sled. The paper consists of the results performed at the pelvis with a linear guided impactor and the comparison of dummy prototype responses and its response requirements.

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• Type de publi. : Communication dans un congrès
• Date de publi. : 20/08/2007
• Auteurs : Jean-Mathias GriessmeierPhilippe ZarkaHanno Spreeuw
• Organismes : Laboratoire d'études spatiales et d'instrumentation en astrophysique Physique des plasmas Laboratoire d'études spatiales et d'instrumentation en astrophysique Physique des plasmas

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• Type de publi. : Article dans une revue
• Date de publi. : 03/08/2007
• Auteurs : Minh-Châu Phan HuyGuillaume LaffontVéronique DewynterPierre FerdinandPhilippe RoyJean-Louis AugusteDominique PagnouxWilfried BlancBernard Dussardier
• Organismes : Laboratoire de photonique et de nanostructures Centre d'Études de Saclay Centre d'Études de Saclay Centre d'Études de Saclay PHOTONIQUE PHOTONIQUE PHOTONIQUE Laboratoire de physique de la matière condensée Laboratoire de physique de la matière condensée
• Publié dans Optics Letters le 30/10/2020

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Résumé : We present a photosensitive three-hole microstructured optical fiber specifically designed to improve the refractive index sensitivity of a standard Fiber Bragg Grating (FBG) sensor photowritten in the suspended Ge-doped silica core. We describe the specific photowriting procedure used to realize gratings in such a fiber. We then determine their spectral sensitivity to the refractive index changes of material filling the holes surrounding the core. The sensitivity is compared to that of standard FBGs photowritten in a six-hole fiber with a larger core diameter. We demonstrate an improvement of the sensitivity by two orders of magnitude and reach a resolution of 3 x 10-5 and 6 x 10-6 around mean refractive index values of 1.33 and 1.40, respectively.

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Fichiers liés : _J-40_-Optics-Letters-2007-32-16-2390-sub.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/08/2007
• Auteurs : Juan Gil YacobazzoPierre-Marie PreuxAhmadou AlioumCarlos KetzoianJean-Claude DesportMichel Druet-CabanacPhilippe Couratier
• Organismes : Neuroépidémiologie Tropicale et Comparée Neuroépidémiologie Tropicale et Comparée Laboratoire de Biostatistique et d'Informatique Médicale Service de l'Information Médicale et de l'Évaluation [CHU Limoges] Neuroépidémiologie Tropicale et Comparée Service d'Hépato-gastro-entérologie et Nutrition [CHU Dupuytren 1, Limoges] Neuroépidémiologie Tropicale et Comparée Service de Santé au Travail [CHU Limoges] Unité Fonctionnelle Registre Général des Cancers du Limousin Neuroépidémiologie Tropicale et Comparée Service de Neurologie [CHU Limoges]
• Publié dans Critical Reviews in Oncology/Hematology le 31/10/2020

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Résumé : Although several prognostic factors have been identified in ALS, there remains some discordance concerning the prognostic significance of the age and clinical form at onset. In order to clarify these findings, we have analysed already known prognostic factors using a multi-state model. Two hundred and twenty-two sporadic ALS patients were followed. A simple unidirectional three-states model was used to summarize clinical course of ALS. States 1 and 2 reflected the progression of neurological impairment and state 3 represented the end of follow-up (tracheotomy or death). Gender, diagnostic delay, body mass index (BMI) and slow vital capacity (SVC) were also recorded. A time-inhomogeneous Markov model with piecewise constant transition intensities was used to estimate the effect of the covariates in each transition. The bulbar form at onset was only correlated with a more rapid clinical progression between state 1 and state 2. In contrast, an advanced age at diagnosis affected only survival from state 2. This methodological approach suggests that these two factors have a different prognostic significance: age at onset is related to patient's survival and the clinical form at onset predicts the progression of motoneuronal impairment in different regions.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/08/2007
• Auteurs : Christophe BureauJuan Carlos Garcia PaganGilles Pomier LayrarguesSophie MetivierPablo BellotPierre PerreaultPhilippe OtalJuan-G AbraldesJean Marie PeronHervé RousseauJaume BoschJean Pierre Vinel
• Organismes : Institut de médecine moléculaire de Rangueil Service de Gastroentérologie et pancréatologie [CHU Toulouse] Hepatic Hemodynamic Liver Unit Liver Unit Institut de médecine moléculaire de Rangueil Hepatic Hemodynamic Liver Unit Liver Unit Service Radiologie et imagerie médicale - Rangueil / Larrey [CHU Toulouse] Hepatic Hemodynamic Liver Unit Service de Gastroentérologie et pancréatologie [CHU Toulouse] Service Radiologie et imagerie médicale - Rangueil / Larrey [CHU Toulouse] Hepatic Hemodynamic Liver Unit Institut de médecine moléculaire de Rangueil Service de Gastroentérologie et pancréatologie [CHU Toulouse]
• Publié dans Liver International le 25/10/2020

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Résumé : An 80% dysfunction rate at 2 years limits the use of transjugular intrahepatic portosystemic shunts (TIPS) in the treatment of complications of portal hypertension. The use of covered stents could improve shunt patency; however, long-term effect and safety remain unknown. Eighty patients randomized to be treated by TIPS either with a covered stent (Group 1) or an uncovered prosthesis (Group 2) were followed-up for 2 years. Doppler US was performed every 3 months. Angiography and portosystemic pressure gradient measurement were performed every 6 months or whenever dysfunction was suspected. Actuarial rates of primary patency in Groups 1 and 2 were 76% and 36% respectively (P=0.001). Clinical relapse occurred in four patients (10%) in Group 1 and 12 (29%) in Group 2 (P<0.05). Actuarial rates of being free of encephalopathy were 67% in Group 1 and 51% in Group 2 (P<0.05). Probability of survival was 58% and 45% at 2 years, respectively, in Groups 1 and 2 (NS). The mean Child-Pugh score improved only in Group 1 (from 8.1+/-1.6 to 7+/-2.2 at 2 years -P<0.05). We also compared the Doppler-US parameters between patent and dysfunctioning shunts. In patent shunts, the mean velocity within the portal vein was significantly higher but the performance of Doppler-US was not accurate enough to predict shunt dysfunction. In conclusion, the improvement in TIPS patency by using covered prostheses is maintained over time with a decreased risk of encephalopathy, while the risk of death was not increased.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/08/2007
• Auteurs : Igor SibonIsabelle CoupryPatrice MénégonJean-Pierre BouchetPhilippe GorryIngrid BurgelinPatrick CalvasIsabelle OrignacVincent DoussetDidier LacombeJean-Marc OrgogozoBenoit ArveilerCyril Goizet
• Organismes : Université de Bordeaux Maladies rares, génétique et métabolisme / Rare Diseases, Genetics and Metabolism Centre Hospitalier Universitaire de Bordeaux Groupe de Recherche en Economie Théorique et Appliquée Geneuro-Innovation Service Génétique Médicale [CHU Toulouse] Service de neurologie [Bordeaux] Service de génétique médicale Epidémiologie et Biostatistique [Bordeaux] Laboratoire de Génétique Humaine, Développement et Cancer Service de génétique médicale
• Publié dans Annals of Neurology le 26/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/08/2007
• Auteurs : Jean-Luc AutranPhilippe RocheJoseph BorelChristophe SudreK. CouliéDaniela MunteanuThierry ParrassinGilles GasiotJean-Pierre Schoelikopf
• Organismes : Institut des Matériaux, de Microélectronique et des Nanosciences de Provence STMicroelectronics [Crolles] Institut des Matériaux, de Microélectronique et des Nanosciences de Provence Institut des Matériaux, de Microélectronique et des Nanosciences de Provence Institut des Matériaux, de Microélectronique et des Nanosciences de Provence STMicroelectronics [Crolles]
• Publié dans IEEE Transactions on Nuclear Science le 31/10/2020

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Résumé : The `' Altitude SEE Test European Platform `' (ASTEP) is dedicated to real-time soft-error rate (SER) testing of semiconductor memories. The platform, located in the French Alps on the `' Plateau de Bure `' at 2552 in, has been operational since March 2006. This test facility includes a proprietary automatic test equipment specially designed for static memory (SRAM) testing and secured remote control operation via internet. First real-time SER measurements on 3.6 Gbit of SRAMs manufactured in CMOS 130 nm technology are reported, as well as the comparison between real-time and accelerated SER. Project perspectives for CMOS 65 nm SRAMs are finally reported.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/08/2007
• Auteurs : Rodolphe AntyEve GelsiJean GiudicelliEugenia Mariné-BarjoanPhilippe GualSylvia BenzakenMarie-Christine Saint-PaulJean Louis SadoulPierre Michel HuetAlbert Tran
• Organismes : Centre méditerranéen de médecine moléculaire Centre Hospitalier Universitaire de Nice Hôpital Archet 2 [Nice] Hépato-Gastroentérologie Observatoire océanologique de Banyuls Centre méditerranéen de médecine moléculaire Laboratoire d’Immunologie [CHU Nice] Pôle Digestif Service d'endocrinologie [CHU Nice] Centre méditerranéen de médecine moléculaire Centre Hospitalier Universitaire de Nice
• Publié dans European Journal of Gastroenterology & Hepatology le 22/10/2020

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Résumé : Steatosis and metabolic abnormalities seem to be frequent and deleterious in chronic hepatitis C. Changes in glucose homeostasis and in adiponectin levels, an adipokine with anti-inflammatory and insulin-sensitive properties, were evaluated in patients with chronic hepatitis C according to steatosis, liver fibrosis and body mass index.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/08/2007
• Auteurs : Carole RossiKaili ZhangDaniel EstèvePierre AlphonsePhilippe TailhadesConstantin Vahlas
• Organismes : Laboratoire d'analyse et d'architecture des systèmes Laboratoire d'analyse et d'architecture des systèmes Laboratoire d'analyse et d'architecture des systèmes Centre interuniversitaire de recherche et d'ingénierie des matériaux Centre interuniversitaire de recherche et d'ingénierie des matériaux Centre interuniversitaire de recherche et d'ingénierie des matériaux
• Publié dans Journal of Microelectromechanical Systems le 28/10/2020

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Résumé : New energetic materials (EMs) are the key to great advances in microscale energy-demanding systems as actuation part, igniter, propulsion unit, and power. Nanoscale EMs (nEMs)particularly offer the promise of much higher energy densities, faster rate of energy release, greater stability, and more security sensitivity to unwanted initiation). nEMs could therefore give response to microenergetics challenges. This paper provides a comprehensive review of current research activities in nEMs for microenergetics application. While thermodynamic calculations of flame temperature and reaction enthalpies are tools to choose desirable EMs, they are not sufficient for the choice of good material for microscale application where thermal losses are very penalizing. A strategy to select nEM is therefore proposed based on an analysis of the material diffusivity and heat of reaction. Finally, after a description of the different nEMs synthesis approaches, some guidelines for future investigations are provided.

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Fichiers liés : rossi_2460.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 01/08/2007
• Auteurs : Valérie BossePhilippe BoulvaisPierre GautierM. TiepoloGilles RuffetJean-Luc Devidal
• Organismes : Laboratoire Magmas et Volcans Géosciences Rennes Géosciences Rennes Géosciences Rennes Laboratoire Magmas et Volcans

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Résumé : The monazite U-Th-Pb chronometer is extensively used to date metamorphic rocks because it is usually considered to be resistant to diffusive Pb loss at temperatures as high as 800°C. However, age perturbations are sometimes documented in monazite grains showing distinct compositional and age domains. The mechanism by which Pb is lost is not well understood. Fluid-assisted recrystallization has been shown to constitute an efficient mean to reset the monazite chronometer in experimental conditions (Seydoux-Guillaume et al. 2002). Whether the same holds true in natural systems remains to be documented. Here we present in situ U-Th-Pb ages on monazite from foliated pegmatitic veins from highly strained levels of the Central Rhodope metamorphic pile (Greece, Bulgaria), together with oxygen isotope characterization and 40Ar-39Ar data. U-Th-Pb ages were obtained by (LA)-ICPMS on 8 monazite grains from three samples. In one sample from Bulgaria, the ages are concordant at 35 Ma, and no chemical zonation is observed. Quartz and feldspar have ..18O values consistent with equilibration at high temperatures. Microfabrics in the vein and the host rocks indicate high grade conditions of deformation. In the two other samples, from Greece, monazite grains show distinct chemical domains and yield discordant U-Th-Pb ages ranging from 52 to 36 Ma. Strong oxygen isotope disequilibrium between quartz and feldspar argues for a complex fluid history: high-..18O fluids first invaded rocks and were followed by low-..18O fluids at lower temperatures. Low temperature fluid circulation at around 36 Ma is consistent with 40Ar-39Ar dating of both samples at 33-34 Ma (mica plateau ages) and with microfabrics documenting a transition from high grade to greenschist facies conditions of deformation during intense shearing. These data confirm the capacity of fluids in disturbing significantly the monazite chronometer.

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