Philippe JEAN-PIERRE

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 06/07/2008
• Auteurs : Joffrey MoirouxCecile Le LannJean-Sébastien PierrePhilippe VernonJoan van BaarenJacques J.M. J.M. van Alphen
• Organismes : Ecosystèmes, biodiversité, évolution [Rennes] Ecosystèmes, biodiversité, évolution [Rennes] Ecosystèmes, biodiversité, évolution [Rennes] Ecosystèmes, biodiversité, évolution [Rennes] Ecosystèmes, biodiversité, évolution [Rennes] Paysages, Changements Climatique, Biodiversité

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2008
• Auteurs : Alexandra GianoncelliJacques CastaingLuc OrtegaEric DooryheeJoseph SalomonPhilippe WalterJean-Louis HodeauPierre Bordet
• Organismes : Centre de recherche et de restauration des musées de France Centre de recherche et de restauration des musées de France X'Press : diffraction et hautes pressions Matériaux, Rayonnements, Structure Centre de recherche et de restauration des musées de France Centre de recherche et de restauration des musées de France Matériaux, Rayonnements, Structure Matériaux, Rayonnements, Structure
• Publié dans X-Ray Spectrometry le 27/10/2020

---

Résumé : A portable system has been recently developed; it combines x-ray fluorescence (XRF) and x-ray diffraction (XRD) techniques, allowing simultaneous elemental analysis and phase identification of inorganic materials. A low power (30 W) air-cooled Cu anode x-ray source is used, equipped with a polycapillary semi-lens to provide a parallel x-ray beam. The system has been designed without mechanical movements and its configuration allows the analysis of objects with arbitrary shapes; the instrument is particularly suitable for material identification in cultural heritage applications where artefacts are non-moveable, and/or exhibit irregular surfaces and shapes. In this article, we present the design of the instrument and the first test measurements. In particular, our results show that it is possible to identify the main crystalline phases present in the samples and to perform the analysis in relatively short times, from 30 min to 1 or 2 h.

---

Source

---

• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 01/07/2008
• Auteurs : Pierre BomelJean-Philippe DiguetGogniat GuyJérémie Crenne
• Organismes : Lab-STICC_UBS_CACS_MOCS Lab-STICC_UBS_CACS_MOCS Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (UMR 3192) Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (UMR 3192)

---

Résumé : In this paper we present a hierarchy of bitstreams repositories for FPGA-based networked and partially reconfigurable systems. These systems target embedded systems with very scarce hardware resources taking advantage of dynamic, specific and optimized architectures. Based on FPGA integrated circuits, they require a single FPGA with a network controller and less external memories to store reconfiguration software, bitstreams and buffer pools used by today's standard communication protocols. Our measures, based on a real implementation, show that our repository hierarchy is functional and can download bitstreams with a reconfiguration speed ten times faster than known solutions.

---

Fichiers liés : ispdc.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2008
• Auteurs : Nathalie LeonePierre DucimetièreJérôme GariépyDominique CourbonChristophe TzourioJean-François DartiguesKaren RitchieAnnick AlpérovitchPhillippe AmouyelMichel E. SafarMahmoud Zureik
• Organismes : Physiopathologie et Epidemiologie de l'Insuffisance Respiratoire Recherche en épidémiologie et biostatistique Centre de Médecine Préventive Cardiovasculaire Physiopathologie et Epidemiologie de l'Insuffisance Respiratoire Neuroépidémiologie Epidémiologie, santé publique et développement Neuropsychiatrie : recherche épidémiologique et clinique Neuroépidémiologie Epidémiologie des maladies chroniques : impact des interactions gène environnement sur la santé des populations Centre de diagnostic Physiopathologie et Epidemiologie de l'Insuffisance Respiratoire
• Publié dans Arteriosclerosis, Thrombosis, and Vascular Biology le 27/10/2020

---

Résumé : OBJECTIVE: Arterial mechanical properties are of growing interest in the understanding of cardiovascular disease development. We aimed to determine the predictive value of carotid wall mechanics on coronary heart disease (CHD) in the Three-City study. METHODS AND RESULTS: At baseline, 3337 participants aged > or =65 years underwent a carotid B-mode ultrasonography. During a median follow-up of 43.4 months, 128 CHD occurred. Increased carotid distension (relative stroke change in lumen diameter) was significantly associated with CHD risk. Comparison of subjects in tertile 3 versus those in tertile 1 (reference) showed a hazard ratio (HR) of 1.80 (95% CI, 1.17 to 2.75). Controlling for various confounders including age, heart rate, brachial (or carotid) pulse pressure, and common carotid intima-media thickness did not alter the association between carotid distension and CHD with a HR of 1.79 (95% CI, 1.12 to 2.86; tertile 3 versus tertile 1). Brachial and carotid pulse pressures were also independently associated with CHD. No association was found between CHD and carotid distensibility coefficient, cross-sectional compliance coefficient, Young's elastic modulus, or beta stiffness index. CONCLUSIONS: In the elderly, increased carotid distension was independently predictive of CHD. This simple and noninvasive parameter might be of particular interest for cardiovascular risk assessment.

---

Fichiers liés : Leone_ATVB_2008.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2008
• Auteurs : Dominique LarrouyPierre BarbeCarine ValleSébastien DejeanVéronique PellouxClaire ThalamasJean-Philippe BastardAnne Le BouilBertrand DiquetKarine ClémentDominique LanginNathalie Viguerie
• Organismes : Institut de médecine moléculaire de Rangueil Institut de médecine moléculaire de Rangueil Institut de médecine moléculaire de Rangueil Institut de Mathématiques de Toulouse UMR5219 Centre de Recherche des Cordeliers CHU Pitié-Salpêtrière [AP-HP] Institut de médecine moléculaire de Rangueil CIC - Biotherapie - Toulouse Pathologie de l'Adipocyte et des Cellules Hepatiques CHU Tenon [AP-HP] Département de la Médecine Département de la Médecine Centre de Recherche des Cordeliers CHU Pitié-Salpêtrière [AP-HP] Institut de médecine moléculaire de Rangueil Laboratoire de Biochimie [CHU Toulouse] Institut de médecine moléculaire de Rangueil
• Publié dans The American Journal of Clinical Nutrition le 29/10/2020

---

Résumé : BACKGROUND: Diet-induced weight reduction promotes a decrease in resting energy expenditure that could partly explain the difficulty in maintaining reduced body mass. Whether this reduction remains after stabilized weight loss is still controversial, and the molecular mechanisms are unknown. OBJECTIVE: The objective was to investigate the effect of a stabilized 10% weight loss on body composition, metabolic profile, and skeletal muscle gene expression profiling. DESIGN: Obese women were assigned to a 4-wk very-low-calorie diet, a 3-6-wk low-calorie diet, and a 4-wk weight-maintenance program to achieve a 10% weight loss. Resting energy expenditure, body composition, plasma variables, and skeletal muscle transcriptome were compared before weight loss and during stabilized weight reduction. RESULTS: Energy restriction caused an 11% weight loss. Stabilization to the new weight was accompanied by an 11% decrease in the resting metabolic rate normalized to the body cellular mass. A large number of genes were regulated with a narrow range of regulation. The main regulated genes were slow/oxidative fiber markers, which were overexpressed, and the gene encoding the glucose metabolism inhibitor PDK4, which tended to be down-regulated. The knowledge-based approach gene set enrichment analysis showed that a set of genes related to long-term calorie restriction was up-regulated, whereas sets of genes related to insulin, interleukin 6, and ubiquitin-mediated proteolysis were down regulated. CONCLUSIONS: Weight loss-induced decreases in resting metabolic rate persist after weight stabilization. Changes in skeletal muscle gene expression indicate a shift toward oxidative metabolism.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 30/06/2008
• Auteurs : Philippe ThomasCyril Hazif-ThomasJean-Pierre Clément
• Organismes : Service de Psychiatrie [CHU Limoges] Neuroépidémiologie Tropicale et Comparée Centre de Mémoire de Ressources et de Recherches [Limoges]
• Publié dans Revue du Praticien (La) le 30/10/2020

---

Résumé : The loss of motivation is frequent in aged person and sometimes is difficult to assess. It is associated with depression but not exclusively. It overlaps with frontal brain aging consequences. Moreover, somatic problems can interfere with a loss of motivation; loss of motivation is frequent with exhausting chronic diseases, cognitive impairment and it facilitates the social withdrawal. In elderly, loss of motivation blunts the intensity of moral pain. Depressions with conative disorders can move in a dysexecutive syndrome. Even if, owing to the treatment, the cognitive disorders disappear, several years after, an authentic dementia can be diagnosed. With aging process, elderly must cope with losses, less or more balanced: affective, physical and financial losses, triggering the reject of any personal commitment. Aging process also concerns brain amines, especially dopamine, exposing old persons to depression. It alters by a similar way others brain neuro-mediator, such acetylcholine, involved in dementia. Both loss motivation and executive disorders have to be systematically assessed. An antidepressant therapeutic is necessary in case of doubt, improving patients thymic status, quality of life of patients and their family, and sometime of frontal dysfunctions.

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 30/06/2008
• Auteurs : Pierre Le SidanerMarie-Lise Dubernet-TuckeyJonathan NormandRenaud SavalleAlbert Y. ShihJerôme BerthierJ. BertinCatherine BoissonJean BorsenbergerIgor V. ChilingarianBertrand de BatzJean-Michel DésertJean GuibertRégis HaigronIsabelle JégouzoFranck Le PetitCoralie NeinerPhilippe PrugnielFabrice RoyFrédéric RoyerJean SchneiderGuy SimonFrançoise TajahmadyWilliam ThuillotFrédéric VachierJacques Vetois
• Organismes : Institut de Mécanique Céleste et de Calcul des Ephémérides Astronomie et systèmes dynamiques Groupe Astrométrie et Planétologie Institut de Mécanique Céleste et de Calcul des Ephémérides Astronomie et systèmes dynamiques Groupe Astrométrie et Planétologie Institut de Mécanique Céleste et de Calcul des Ephémérides Astronomie et systèmes dynamiques Groupe Astrométrie et Planétologie

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 30/06/2008
• Auteurs : Marc WessnerMartin SengerFranck SamsonPhilippe PicouetFrançois MoreewsHervé MénagerVéronique MartinSébastien LetortCatherine LetondalMark HoebekeJerome GouzyJean-François GibratErwan CorreOlivier CollinSébastien CarrereChristophe CaronPierre TufféryBertrand Néron
• Organismes : Unité de Biologie du développement et biotechnologies Physiologie Moléculaire du Transport des Sucres chez les Végétaux Unité Mathématique Informatique et Génome Département Logique des Usages, Sciences sociales et Sciences de l'Information Lab-STICC_TB_CID_DECIDE Biological systems and models, bioinformatics and sequences Institut Pasteur [Paris] Unité Mathématique Informatique et Génome Institut National de la Recherche Agronomique Institut Pasteur [Paris] Laboratoire Statistique et Génome Laboratoire des interactions plantes micro-organismes Unité Mathématique Informatique et Génome Unité Mathématique Informatique et Génome Végétaux marins et biomolécules Biological systems and models, bioinformatics and sequences Laboratoire des interactions plantes micro-organismes Unité Mathématique Informatique et Génome Bioinformatique génomique et moléculaire Modélisation mathématique et statistique en biologie et médecine Institut Pasteur [Paris]

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 29/06/2008
• Auteurs : Jean-Pierre MathieuJonas HoffmannGilles RoehrichPhilippe Mallein
• Organismes : Audencia Business School

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 29/06/2008
• Auteurs : Jean-Michel KrysieckiXavier BodinPhilippe Schoeneich
• Organismes : Pôle de recherche pour l'organisation et la diffusion de l'information géographique Pacte, Laboratoire de sciences sociales Systèmes Environnementaux, Information Géographique et Aide à la Décision

---

Source