Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2024
• Auteurs : Antoine PegatJean-Baptiste ChansonPierre LozeronBastien JoubertAlexandre Bani-SadrIsabelle QuadrioLéo VidoniPhilippe Latour
• Organismes : Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL] Hôpitaux Universitaires de Strasbourg Hôpital Lariboisière-Fernand-Widal [APHP] Centre Hospitalier Lyon Sud [CHU - HCL] Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL] Radiopharmaceutical and Neurochemical Biomarkers Service de Biochimie et Biologie Moléculaire Grand Est [HCL, Lyon] Service de Biochimie et Biologie Moléculaire Grand Est [HCL, Lyon] Service de Biochimie et Biologie Moléculaire Grand Est [HCL, Lyon]
• Publié dans Journal of Neuroimmunology le 22/10/2020

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Résumé : Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is a rare immune-mediated neuropathy for which there is no clearly identified risk factor. The present study identified rare variants in the FBXO38 gene in three familial cases of CIDP with response to corticosteroids in three generations with incomplete penetrance, and in an unrelated fourth case with diffuse nerve hypertrophy. FBXO38 may be involved in the regulation of the immunity mediated by CD8 T cells, which have an important role in CIDP pathophysiology, through PD1 degradation. Considering these findings, FBXO38 should be investigated as a potential genetic factor in larger cohorts of patients with CIDP.

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Fichiers liés : PIIS0165572824000997.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2024
• Auteurs : Emilie DocheConstance SulowskiJean-Marie GuigonisFanny GraslinBarbara CasollaJean-François HakXavier CarleHervé BrunelSabine LindenthalJean-Charles MartinThierry PourcherLaurent SuissaMarie-Christine AlessiMickael BobotAbdelmalek BrinetSonia DagninoJean-Daniel DehondtSilvia Di LeggePhilippe Dory-LautrecCecile Dulau-MetrasPierre DurozardBasile KerlerouxNadia LaksiriBarbara LeclercqPierre LehmannEllen MagonciaChristine ManzacOphelie OsmanRoxane PeresSandra PerezCaroline ReyAnthony ReyreEmmanuelle Robinet-BorgomanoSalome SnymanLjubica SvilarCatherine TardivelPatricia TourniaireSivadji Vingadalassalom
• Organismes : Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research
• Publié dans Stroke le 31/10/2020

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Résumé : BACKGROUND: The dramatic clinical improvement offered by mechanical thrombectomy raised questions about the relevance of prior intravenous thrombolysis in large-vessel occlusion strokes. Hence, studying intravenous thrombolysis susceptibility and its dependence on thrombus composition is crucial. We used an observational proteomic study of whole thrombi retrieved by mechanical thrombectomy to identify factors associated with fibrin content and fibrinolytic activity (FA). METHODS: In 104 stroke patients, the thrombi proteome was established by mass spectrometry coupled to liquid chromatography. FA was estimated in clots both outside (FA out ) by measuring D-dimer levels at the blood-thrombus interface and inside (FA in ) by evaluating the ratio of fibrinogen α to its plasmin-cleaved forms using proteomics coupled with protein electrophoresis. The factors associated with fibrin content, FA in , and FA out were determined by intravenous thrombolysis-adjusted linear regression. RESULTS: FA out ( P <0.0001) and FA in ( P =0.0147) were driven by recombinant tissue-type plasminogen activator (r-tPA) administration (47/104) and thrombus composition. Indeed, FA out was greater with fibrin-rich than erythrocyte-rich thrombi, presumably because of more (r)tPA substrates. Thus, FA out was increased with cardioembolic thrombi (72/104), which are rich in fibrin ( P =0.0300). Opposite results were found inside the thrombus, suggesting that (r)tPA penetrability was hampered by the density of the fibrinous cap. Moreover, blood cells had a strong impact on thrombus structure and susceptibility to (r)tPA. Indeed, fibrin content was negatively associated with erythrocyte-specific proteins in the thrombus, admission hematocrit ( P =0.0139), and hemoglobin level ( P =0.0080), which underlines the key role of erythrocytes in thrombus composition. Also, an increased number of neutrophils impaired FA out ( P =0.0225), which suggests that their aggregation around the thrombus prevented the (r)tPA attack. Only FA out was significantly associated with reduced thrombus weight ( P =0.0310), increased recanalization rate ( P =0.0150), good clinical outcome ( P =0.0480), and reduced mortality ( P =0.0080). CONCLUSIONS: Proteomics can offer new insights into the close relationship between thrombus composition and susceptibility to fibrinolysis, paving the way for new adjuvant therapies.

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Fichiers liés : 113 How Clot Composition Influences Fibrinolysis in the Acute.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2024
• Auteurs : Willy SutterJean-Marc AlsacIannis Ben AbdallahCassandre MichelPierre JuliaJean-Philippe EmpanaSalma El Batti
• Organismes : Epidémiologie intégrative des maladies cardiovasculaires = Integrative epidemiology of cardiovascular diseases Innovations thérapeutiques en hémostase = Innovative Therapies in Haemostasis Epidémiologie intégrative des maladies cardiovasculaires = Integrative epidemiology of cardiovascular diseases Innovations thérapeutiques en hémostase = Innovative Therapies in Haemostasis
• Publié dans Annals of Vascular Surgery le 26/10/2020

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Résumé : Backgroud: The learning curve and midterm results of aortoiliac occlusive disease (AIOD) revascularization by robot-assisted laparoscopic (RAL) surgery may be known. Methods: A prospective single-center study was conducted in the vascular surgery department of Georges Pompidou European Hospital (Paris, France). Patients with AIOD treated by RAL from February 2014 to February 2019 were included. Demographic characteristics, past medical history, Trans-Atlantic Inter-Society Consensus (TASC) lesions classifications, mortality, primary and secondary patency, as well as complication rates were collected. Safety was analyzed by the cumulative sum control chart method with a conversion rate of 10%, operative time by cumulative average-time model, and primary and secondary patency by the Kaplan-Meier method. Results: Seventy patients were included, 18 (25.7%) with TASC C lesions and 52 (74.3%) with TASC D lesions. Before discharge, 14 (24.3%) patients had surgical complications. Among them, 10 (14.3%) required at least one reintervention. One (1.4%) patient died during the hospitalization. The learning curve in terms of safety (conversion rate) was 13 cases with an operating time of 220 minutes after 35 patients. During follow-up (median 37 months [21; 49]), 63 patients (91.3%) improved their symptoms, 53 (76.8%) became asymptomatic, and 3 graft limb occlusions occurred. The primary patency at 12, 24, 36, and 48 months was 94%, 92%, 92%, and 92%, respectively, while the secondary patency for the same intervals was 100%, 98.1%, 98.1%, and 98.1%, respectively. Conclusions: Robotic surgery in AIOD revascularization seems safe and effective; allowing to treat patients with few comorbidities and severe lesions, in a dedicated center experienced in RAL, with excellent patency. Prospective clinical trials should be performed to confirm safety.

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Fichiers liés : 1-s2.0-S0890509624001857-main.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2024
• Auteurs : Pedro Jiménez-MejíasSaúl ManzanoVinita GowdaFrank-Thorsten KrellMei-Ying LinSantiago Martín-BravoLaura Martín TorrijosGonzalo Nieto FelinerSergei L MosyakinRobert F C NacziCarmen AcedoInés ÁlvarezJorge V CrisciModesto Luceño GarcésJohn C. ManningJuan Carlos Moreno SaizA. Muthama MuasyaRicarda RiinaAndrea Sánchez MeseguerDaniel Sánchez-MataMagdi S A El-HawagryMohammad Amini RadPatrick BlandinMichael SchmittRyota HayashiSangtae KimAnna RonikierMichał RonikierSergio ChozasAndreia AnjosGuilherme Siniciato Terra GarbinoMikhail RogovManuel B MoralesCarlos Luis Leopardi VerdeEmre ÇildenDonald ShukaErmelinda GjetaLulëzim ShukaMarjol MecoSpase ShumkaAbdelkader Nabil BenghanemDjilali TahriLaouer HocineRachid MeddourSaidi BoubakrSalima BenhouhouClara PladevallFrancisco Maiato Pedro GonçalvesAbel Pérez-GonzálezAna Valeria CarranzaAnibal Oscar PrinaDarién E PradoDiego G GutiérrezElián L GuerreroEsteban O LavillaEugenia MinghettiFederico AgnolínGraciela Lorna AlfosnoJuan José CanteroJulian FaivovichLiliana KatinasMagdalena LauritoMarcelo AranaMaria Cecilia MeloMaria Jimena PonceMariela FabbroniPablo Edmundo OrtizPablo Horacio DemaioPablo M DellapéPablo TetaRoberto KieslingAlla AleksanyanGeorge FayvushBrian JonesDaniel J BickelEckart HåkanssonElena KupriyanovaGlenn SheaJürgen KellermannKaren L WilsonLadislav MucinaNicholas MorrisPeter CranstonPeter CrossingPeter G AllsoppPeter WestonRaymond HoserRohan PethiyagodaScott EipperTrevor Henry WorthyVratislav Ricardo Bejsak-Colloredo-MansfeldBožo FrajmanClemens PachschwöllGerald M SchneeweissGerhard PilsHermann VoglmayrIrmgard Krisai-GreilhuberKonstantina AgiadiMichael H J BarfussPeter SchönswetterWolfgang WillnerAlexander LukashukValery N TikhomirovAchik DorchinArnaud Henrardde Blauwe HansFilip VerlooveGuy SmaggheJacques VerniersJan BosselaersJérôme DegreefKenny MeganckLars ChatrouLouis BeyensLuis M da CostaMarc SosefOlivier S G PauwelsPaolo RosaPaul SchoolmeestersPol LimbourgRobbert GradsteinRobert SpeijerSalvator NtoreThomas James WoodWilly de PrinsNourou Soulemane YorouJigme WangchukLizette SilesLuis F AguirreLuis Fernando Aguirre UriosteMagaly Mercado UMarita A Pareses-RodríguezMauricio OcampoPamela Jenny Carvajal BacarrezaAvdul AdrovićSadbera Trožić-BorovacDemel Teketay FantaAdriano Brilhante KuryAndré HoffmannAndré Silva FernandesAxel KatzBruno Machado Teles WalterClapton Olimpio de MouraCristiano Lopes-AndradeDalton de Souza AmorimDaniel C CavallariDaniel LoebmannDiego Aguilar FachinDiego Nunes da SilvaFernando Z Vaz-de-MelloFrancisco Langeani NetoGerson Paulino LopesHenrique C CostaHenrique Mallmann BünekerIsabel Paiola GonçalvesJohn E LattkeJose Albertino RafaelJosé Nascimento JrJosé Rubens PiraniJosimar KülkampJulian C G Silva JrKatyuscia Araujo-VieiraLeandro Lacerda GiacominLeandro Manzoni VieiraLeandro Tavares Azevedo VieiraLeonardo M BorgesLeonardo M VersieuxLucas Cardoso MarinhoLucas Sá Barreto JordãoLuciano Paganucci de QueirozMarcelo TrovóMarcelo WekslerMarcos Gonçalves LhanoMaria Beatriz Rossi CaruzoMarinus S HoogmoedMaurício FigueiraMiguel MedranoMilton GroppoOmar Rojas PadillaOtávio Luis Marques da SilvaPatricia Jacqueline ThyssenPedro Henrique CardosoRafael A P Freitas SilvaRenata TrevizanRicardo de S SeccoRosângela Simão-BianchiniScott ThomsomTamily Carvalho 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CondamineFranck MaddiFrançois DusoulierFrançoise ChalieFrançoise Debierre-GrockiegoFrédéric DanetFrédéric DucarmeGael KergoatGerminal RouhanGildas GatebleGilles CunyGrégory KaradjianGuillaume ViscardiHenri SavinaHerve JourdanIvan IneichJavier Fernández-LópezJean-Bernard HuchetJean-Charles GantierJean-Christophe de MassaryJean-François JossoJean-François TrapeJean-Georges HarmelinJean-Louis LatilJean-Marc TisonJérôme BarbutJérôme DepaquitJérôme MunzingerJuliana ProsperiJulien EngelLilou LeonettiMarc PhilippeMichaël RabillerMichel LaguerreMonique Vianey-LiaudNicole Boury-EsnaultOlivier MontreuilPatrice LerautPhilippe BouchetPhilippe MorettoPierre-Olivier MaquartRomain GarrousteRudelle RémiSerge GadoumStéphane BuordSuzanne LeroySylvie DeschampsTeddy BruyThibault RamageThierry BourgoinThierry DeuveVincent LuccisanoViolaine NicolasLiwouwou Jean FelicienAchille KuateAndre SkaleAndreas KopetzAndreas ReichenbachAndreas WeigelAndrii TarieievBirgit BalkenholBjoern RulikChristoph HöpelChristoph OberprielerChristoph ReuteDaniel Montesinos-TubéeDirk AhrensDirk AlbachDirk MatternEberhard FischerEduardo MarabutoEric AntonFrancisco Hita-GarciaFrank CreutzburgFrank FritzlarHans FeryHans-Walter LackHelmut FreitagHolger DombrowHorst KippenbergJendrian RiedelJens KippingJoachim SchmidtJochen MülleJohan RovaJohn HutchinsonJörg GebertJulia SigwartJürgen WiesnerKarsten WescheManfred UlitzkaMarcel MüllerMarianne EspelandMatthias HartmannMaximilian WeigendMónica Solórzano-KraemerPaul LamkowskiPeggy LommatzschReza ZahiriSebastian GebauerSigfrid IngrischThomas GregorVictor ChepinogaVolker PuthzVolker von WirthAris ZografidisDionysios MermygkasGeorgios FotiadisPanayotis DimopoulosJavier Aju-TorresOsberth Morales-EsquivelLilian Ferrufino-AcostaArnold MóraBalázs TóthBálint PerneckerBarna Páll-GergelyCsaba CsuzdiÉva SzitaJenő KontschánLuca Eszter BalogPál BodaPéter KóborSándor HornokTamás NémethTamás SzűtsViktória SzőkZoltán CsabaiZoltán FehérZoltán VasGuðmundur GuðmundssonAnila AjayanAparna 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KumaranSuganthi AppalasamyAlexey ProzorovJacques DembeleAna María Hanan AlipiAniceto Rodolfo Solano GomezBeatriz Maruri-AguilarClaudia Janeth Ramírez DíazClaudio Delgadillo-MoyaDavid Alexander Prieto TorresDr Gopal MuruganEduardo Ruiz SánchezEmiliano Sánchez MartínezFelipe Gómez-NoguezGermán Carnevali Fernández-ConchaGustavo Montiel CanalesIvón Ramírez-MorilloJ Daniel Tejero-DíezJ Rolando Bastida-ZavalaJorge MeaveJosé Fernando Alvarado RodríguezLauro López MataLeonardo Osvaldo Alvarado CárdenasM Socorro González-ElizondoManuel González LedesmaMaría del Socorro García-MadrigalMaría Magdalena Hernández MartínezMartha González ElizondoNeptalí Ramírez-MarcialRamon Cuevas GuzmanRodrigo Stefano DunoRubén Martínez-CamiloTeresa TerrazasViacheslav ShaliskoVictor BarradasJ Adilson Pinedo-EscatelBazartseren BoldgivChambouleyron MathieuClaude LermmelJean-François LégerHarith FarooqJohn IrishKrishna ShresthaA DopAlexandra van der GeerAndré van EckAngelica Cibrian JaramilloE EgbertsEdwin PeetersErik 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GusarovAbdul MajidUzma HanifAnnette AielloJuan CarriónBolívar Garcete-BarrettNelida Soria ReyAsunción CanoCarlos Reynel RodriguezDin Olger Heredia HuarinoElva Fany PalominoGiussepe Gagliardi-UrrutiaGuillermo PinoItalo Francisco Treviño ZevallosJenny Rojas-FoxJorge Luis Cabrera MeléndezThomas ValquiAimee Lynn DupoCristian LucanasDavid Emmanuel M GeneralHaira Jill TolentinoIreneo LitMichael Agbayani CalaramoAdam KaczmarekAndrzej KaimArtur TaszakowskiBarbara Tokarska-GuzikBogdan WiśniowskiHanna MoniuszkoHelena WięcławIván García-CunchillosJacob KoopmanJarosław TyszkaJerzy LisKenneth de BaetsKrzysztof HryniewiczMarcin PiątekMarek WanatMarta ZakrzewskaMateusz TałandaPiotr KuklinskiRusłan SałamatinWojciech SolarzAndré de Matos Casimiro Justo CarapetoAndreu Santín MurielAntónio José CaladoArtur SáArtur SerranoCarlos Góis-MarquesCarlos Dinis PenedoCarlos Vila-ViçosaDiogo ParrinhaIris SampaioJoão FarminhãoJorge CapeloJosé Manuel Grosso-SilvaLeonel PereiraLuis Filipe LopesLuis CeríacoMarta BentoMartin CorleyMiguel Menezes de SequeiraNeftalí SilleroOctávio MateusPatricia EsquetePaulo OliveiraPedro NavesRafael CarvalhoRaquel Juan-OvejeroRoberto KellerSérgio TimóteoThiago SemedoUdo SchwarzerPatricia BurrowesMuhammad Ali NawazAdrian IndreicaAdrian OpreaAlma NicolinCatalin TanaseCosmin-Ovidiu ManciDan CogalniceanuDorel RuştiElena IorguEszter RuprechtFloriana PopescuGabor MajorosGavril Marius BerchiIonut Stefan IorguIrina IrimiaKuhn ThomasLucian FusuLucian PârvulescuMarius SkolkaMihai PuscasPaulina AnastasiuPeter Laszlo PapAleksandr EvsyukovAlexander BannikovAlexander KarhuAlexander KudryavtsevAlexander ProkinAlexander ProsvirovAlexandr EbelAlexandr RasnitsynAlexandr StekolnikovAlexei KravchenkoAlexey KotovAlexey MedvedevAlexey BashkuevAlexey PakhnevichAlexey ShmakovAlexey LopatinAlisa NeplyukhinaAndrei LegalovAndrey SamdanAndrey MatalinAndrey ZhuravlevArtem LeostrinArtem SinevBoris KorotyaevBoris KataevDavidian GenrikDmitry LifanovDmitry FedorenkoDmitry KopylovDmitry LyskovDmitry SokoloffDmitry VorontsovEduard MychkoEfremov AndreyEgorov LeonidEvgeniy DunayevEvgeniya MuchnikEvgeny PopovGennady BaryshnikovGeorgy MirantsevGyulli FarzalievaIgor FefelovIrina SamsonovaKirill MikhailovKirill MakarovKonstantin TarasenkoKsenia KlimovaLarisa BagmetLev ShestakovLovtsova JuliaLyudmila Mikhailovna PavlovaMaxim NabozhenkoMaxim NuralievMaxim VinarskiMelnikov Denis GMichael SerebryanyiNatalia TerekhinaNatalya AndreyenkovaNikita ZdravchevNikita ZelenkovNikolay PoyarkovPavel KhramtsovPavel ParkhaevPeter KhramovRoman NazarovSergei TshernyshevSergey SinevVladimir FedosovVladislav DesiatkinYuri MikhailovYurii SundukovZinovyev EvgeniyAhmed SolimanAbdoulaye Baïla NdiayeMingou Paterne Arnaud BernardAleksandar ĆetkovićAnđeljko PetrovićDalibor StojanovićMihailo VujićMirko ŠevićPredrag SimonovićSaša MarićVera NikolicVukašin GojšinaJohn AscherAdam KantorAnna GuttovaDaniel JablonskiJudita ZozomováKarol MarholdPavol MereďaStanislav ŠpanielVladimír HemalaAndraž ČarniFaisal Jama GelleBenny BytebierChristian DeschodtDavid Gwynne-EvansDenis BrothersGimo DanielHester SteynIan EngelbrechtJacques van RooyJanine VictorJanneke AylwardLynne QuickMike MostovskiMusa MlamboRiaan StalsRuan van MazijkSusan DippenaarVinícius da Costa-Silvaa Jesús Muñoz-PajaresAaron Pérez-HaaseAgustin LahoraAlberto Rodríguez-FernándezAna Beleén Fernández SaleguiAna García-MuñozAna María Vega MarayAna Morales-AlonsoAna Ortega-OlivenciaAndres BaselgaAndres OrdizÁngel Fernández CeularAntonio Flores-MoyaAntonio Galán de MeraAntonio García-TaberneroArturo Goldarazena LafuenteBaltasar CabezudoBárbara Díez-RodríguezBelén Albertos BofarullBelén Estébanez PérezCandela Blanco MorenoCarlos LadoCarlos HerreraCarlos Romero-ZarcoCarlos Salazar MendíasCarmen Bartolomé EstebanCarmen Benítez BenítezCésar Morales-MolinoCristian AltabaCristina González MontelongoDaniel Pinto-CarrascoDavid SerranoEduardo CiresEduardo NarbonaElena ÁlvarezEmilio LagunaEmma OrtúñezEnrique LaraEnrique MaguillaEnrique Peñalver MolláEsperanza Beltrán TejeraEsther San José CarrerasEstrella Alfaro-SaizEusebio López NietoF Javier Jiménez-LópezF Xavier PicóFederico Fernández-GonzálezFélix LlamasFélix Torres GonzálezFernando OjedaFrancisco BalaoFrancisco CabezasFrancisco ValtueñaFrancisco Javier Rejos BallesterosFrancisco LaraFrancisco VázquezGabriel BlancaGabriel Mercadal I CorominasGabriel MorenoGloria Martínez-SagarraGraciela Gil RomeraGregorio García Sánchez-RamalGuillermo BenítezIgnacio LazagabasterIgnacio de la RivaIrene Masa-IranzoIris Montero MuñozIsabel DraperIsabel SalcedoJavier Diéguez UribeondoJavier EtayoJavier Fabado AlósJavier Fuertes AguilarJavier Galán-DíazJesús MuñozJoaquín BaixerasJoaquina María García MartínJordi López-PujolJosé MejíasJose Carlos MirandaJosé Gabriel Segarra-MoraguesJosé Ignacio Lucas LledóJosé Luis Blanco PastorJosé Luis YelaJosé Blanco-MorenoJosé María CardielJosé María IriondoJose María Maya ManzanoJosé Ramon Grande AllendeJosé Vicente Andrés RosJose Vicente Pérez Santa-RitaJosé-Miguel Carretero DíazJosefa López MartínezJosep NinotJosep Padullés CubinoJoshua BorràsJuan AlarcónJuan Antonio DevesaJuan Carlos Gutiérrez-MarcoJuan UribeJuan MotaJuan José Pino PérezJuan LoriteJuan RubialesJuan LabargaJuan MonrósJuan GonzálezLaura Rodriguez GarciaLeopoldo Medina DomingoLlorenç SaezLluis Serra LaligaLourdes López MerinoM Luisa Buide del RealM Mar TrigoM Montserrat Martínez-OrtegaMagdalena Vicens FornésManuel Rodriguez-IglesiasManuel de la EstrellaManuel MacíaManuel Sánchez-AnguloMarcial EscuderoMaría Luisa Navarro PérezMaría Sanz ArnalMario Fernández-MazuecosMarta AlcoleaMiguel Ángel Gómez-SerranoMiquel CapóMohamed AbdelazizMónica Miguez RíosNereida Rancel-RodríguezOscar Reverter-GilPablo García MurilloPablo Muñoz-RodríguezPablo Tejero IbarraPablo VargasPaloma CantóPascual López-LópezPedro Pérez OleaPedro Sánchez GómezPenélope González-SampérizPere Fraga I ArguimbauRafael MedinaRafael Molina VenegasRaquel Alonso RedondoRaquel Pino BodasRaúl Lois MaderaRaúl Ochoa-HuesoRaúl Orihuela-RiveroRaúl Sánchez FrancésRegina BerjanoRicardo GarilletiRodrigo GranjelRogelio Sánchez VillegasRosa Mª Valencia BarreraRosario GavilanRosina Magaña UgarteRubén MateoRuymán David Cedrés-PerdomoSantiago Andrés SánchezSantiago Castroviejo-FisherSantiago Fernández JiménezSantiago OrtizSara del RíoSara RomeroSergio Pérez-OrtegaSilvia Gómez ValleSonia MolinoTeresa GarnatjeTomás Rodríguez RiañoVíctor RicoVictoria Ferrero VaqueroVioleta AtienzaVioleta Simón-PorcarVirginia ValcárcelWilliam Douglas CarvalhoWolfgang DenzerYoana García MendizabalBengt Å BengtssonBengt CarlssonBrita SvenssonCarlos Guerrero BosagnaEric WahlsteenGöran ArnqvistIrene BisangJadranka RotaJohan LiljebladKennet LundinKnud Andreas JønssonLars HedenäsMats WedinMichael NorénNiklas WahlbergPaco CárdenasPer AhlbergPer AlströmPer LöfgrenPeter NielsenSabine StöhrSteffen KielTorbjörn TylerUlf ArupZongzhuang LiuArne StridGerman Hernández AlonsoAlain ChautemsAna García-MartínAndré CharpinAndreas MüllerAnne FreitagBernard LandryChristophe PrazDanae ThivaiouDaniel CherixDaniel JeanmonodEdward MitchellFlorian MombrialGiulio CuccodoroGuido SabatinelliIvan LöblJean MariauxJean-Paul HaenniJean-Paul TheurillatJuan Carlos ZamoraLaurent ValtottonManuel RuediMarvco BernasconiNicolas FumeauxOliver HawlitschekPeter SchuchertPhilippe ClercSeraina KlopfsteinAdun SamathiKevin HydeRaoufou RadjiJ Francisco MoralesFaouzia CharfiRidha El MokniFiliz GunaySaida AgayevaAlessandro GiustiAndré SchuitemanAndrew WhittingtonArchie Yf KoAshley LeftwichChristopher David WilliamsClare ScanlanCrispin LittleDanniella SherwoodDavid LeesDavid GoyderDavid Michael JohnEdward DickinsonGeorge BeccaloniHenry NoltieIan McleanIsabel LarridonJohn BadminJohn McarthurJohn NoyesJonathan ToddLeonidas Romanos DavranoglouMark ShawMark YoungMartin EbejerMartyn KellyMaurizio DioliMaxwell BarclayMichael GeiserNick StewartPeter LangtonRichard BatemanRob MarchantSimon SchneiderTabitha TabererTammy HortonVladimir BlagoderovWolfgang WüsterZhe-Yu ChenDmitry TelnovAndriy NovikovDmytro DubynaIgor BalashovIhor OlshanskyiMykola FedoronchukNatalia ShiyanOleksandr KhodosovtsevOleksandr KovalchukOxana VinogradovaTatiana MikhailyukVasily DyadichkoVera HayovaViktor NachychkoVitalii KolomiichukVitaliy KharchenkoEvgeny PerkovskyAry MailhosEduardo MarchesiJose Mauricio BonifacinoMaría Victoria Valtierra SierraAaron BauerAdeyinka AdeyemiAlan FranckAlessandra PandolfiAllen NorrbomAndre MoncrieffAndrew JohnsonAngelo CapparellaAnthony RossiArmin NamayandehArt BorkentBarbara HellenthalBrett RatcliffeBrian O'SheaBrian Tilston SmithC Jonathan SchmittCamm SwiftChris CohenChristopher BorkentD Christopher RogersDale CasamattaDaniel KoenemannDavid BouffordDavid CampbellDavid KrauseDavide Dal PosDerek SikesDon LesEdward DekeyserEdwin Cruz-RiveraEmily CarterGlenn Fairbanks SeeholzerGuy ErohH Douglas PrattHinrich KaiserIrene Villa MachioJ Mark EggerJ RemsenJacob EsselstynJames Christopher SagebielJames LiebherrJames HogheJared WolfeJason DombroskieJessica EberhardJimmy McguireJohn GerwinJohn EplerJosé LealJose Lopez-RibotJudith WinstonJulian HarberJun WenJustin LeeJustin PargeterKatharine GreggKeith ArnoldKenneth CarpenterKevin MccrackenKevin WilliamsKevin WinkerKipling WillKyhl AustinKyle HarmsLes WatlingLinda WatsonManuel MarinMarc Edward EpsteinMarcus KeyMariana MarquesMark PyronMartin DovciakMartin HauserMary Jane West-EberhardMauricio DiazgranadosMel WarrenMichael OliverMichael FerroMichael EngelNatalia von EllenriederNathan Burkett-CadenaNeal EvenhuisNeil SnowNobuaki MizumotoObediah SagePatrick RakesPatrick RohnerPaul MorrisPaula CushingPaula Rozo-LopezPaulo Durães Pereira PinheiroPeter KerrPeter StevensPeter UetzQuentin WheelerR Edward DewaltR Kevan Schoonover McclellandRichard ZanderRichard RabelerRobert ZuparkoRobert HansenRoberta BrettRonald HellenthalRose MeierRosser GarrisonRoy GereauSam HeadsSamuel McleodSamuel Wooster JamesSeveryn KorneyevShaun WintertonStephen GaimariSteve HiltySubir ShakyaSusan AdamsSusan LetcherThomas AtkinsonTimothy WoodVictor GonzalezWalsh SjWendy ApplequistWilliam Smith-VanizWilliam MurphyWilliam Wayt ThomasKhalimov F ZMukhammadtuychi RakhimovShodmonov Feruz AbdullajonovichYigitali TashpulatovFernando Rojas-RunjaicHugo Gullermo Cerda PérezPedro TorrecillaThirza Ruiz ZapataHoang Quynh HoaNgoc NguyenCathy SharpMoira Fitzpatrick
• Organismes : Universidad Pablo de Olavide [Sevilla] Universidad de León = University of León [León] Indian Institute of Science Education and Research Bhopal Denver Museum of Nature and Science Mianyang Normal University, Mianyang (MYNU) Universidad Pablo de Olavide [Sevilla] Real Jardín Botánico de Madrid Real Jardín Botánico de Madrid National Academy of Sciences of Ukraine = Національна академія наук України = Académie nationale des sciences d'Ukraine New York Botanical Garden Universidad de León = University of León [León] Real Jardín Botánico de Madrid Facultad de Ciencias Naturales y Museo [La Plata] Universidad Pablo de Olavide [Sevilla] South African National Biodiversity Institute Universidad Autónoma de Madrid University of Cape Town Real Jardín Botánico de Madrid Real Jardín Botánico de Madrid Universidad Complutense de Madrid = Complutense University of Madrid [Madrid] Harvard University Cairo University Research Institute of Forests and Rangelands Muséum national d'Histoire naturelle Universität Greifswald = University of Greifswald Research & Development Center Sungshin Women's University W. Szafer Institute of Botany W. Szafer Institute of Botany Centre for Ecology - Evolution and Environmental Changes Centre for Ecology - Evolution and Environmental Changes Universidade Federal de Viçosa [Brasil] = Federal University of Viçosa [Brazil] = Université fédérale de Viçosa [Brésil] Geological Institute of the Russian Academy of Sciences Universidad Autónoma de Madrid Universidad de Colima [Mexico] Hacettepe University = Hacettepe Üniversitesi University of Vlora "Ismail Qemali" University of Tirana - Université de Tirana [Tirana, Albania] University of Tirana - Université de Tirana [Tirana, Albania] University of Tirana - Université de Tirana [Tirana, Albania] Agricultural University of Tirana Ecole Nationale Supérieure Agronomique d'Alger Université Amar Telidji - Laghouat Constantine 1 – Frères Mentouri University = Université Frères Mentouri Université Mouloud Mammeri [Tizi Ouzou] = Mouloud Mammeri University of Tizi-Ouzou Université Ibn Khaldoun de Tiaret = University of Tiaret Ecole Nationale Supérieure Agronomique d'Alger Andorra Recerca+Innovació Herbário do Lubango Museo Argentino de Ciencias Naturales ‘Bernardino Rivadavia' [Buenos Aires] Universidad Nacional de Jujuy Universidad Nacional de lLa Pampa Instituto de Investigaciones en Ciencias Agrarias de Rosario [Zavalla] Museo Argentino de Ciencias Naturales ‘Bernardino Rivadavia' [Buenos Aires] División Plantas Vasculares [La Plata] Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] Fundación Miguel Lillo, Tucumán Facultad de Ciencias Naturales y Museo [La Plata] Museo Argentino de Ciencias Naturales ‘Bernardino Rivadavia' [Buenos Aires] Facultad de Ciencias Exactas y Naturales [Buenos Aires] National University of Río Cuarto = Universidad Nacional de Río Cuarto Museo Argentino de Ciencias Naturales ‘Bernardino Rivadavia' [Buenos Aires] Facultad de Ciencias Naturales y Museo [La Plata] Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] Universidad Nacional de Chilecito National University of Río Cuarto = Universidad Nacional de Río Cuarto Facultad de Ciencias Exactas [La Plata] Instituto Multidisciplinario de Biología Vegetal [Córdoba] Facultad de Ciencias Naturales [Salta] Instituto Superior de Investigaciones Biológicas [Tucumán] Universidad Nacional de Catamarca Facultad de Ciencias Exactas [La Plata] Museo Argentino de Ciencias Naturales ‘Bernardino Rivadavia' [Buenos Aires] Consejo Nacional de Investigaciones Científicas y Técnicas [Buenos Aires] National Academy of Sciences of the Republic of Armenia [Yerevan] National Academy of Sciences of the Republic of Armenia [Yerevan] Murdoch University [Perth] Australian Museum [Sydney] The University of Western Australia Australian Museum Research Institute Sydney School of Veterinary Science State Herbarium of South Australia Royal Botanic Gardens [Kew] Murdoch University [Perth] The University of Western Australia Australian National University Auteur indépendant Queensland Museum National Herbarium of New South Wales Auteur indépendant Australian Museum Research Institute Nature4You Flinders University [Adelaide, Australia] Macleay Museum Leopold Franzens Universität Innsbruck - University of Innsbruck Universität Wien = University of Vienna Universität Wien = University of Vienna Universität für Bodenkultur Wien = University of Natural Resources and Life Sciences [Vienne, Autriche] Universität Wien = University of Vienna Universität Wien = University of Vienna Universität Wien = University of Vienna Universität Wien = University of Vienna Leopold Franzens Universität Innsbruck - University of Innsbruck Universität Wien = University of Vienna Berezinsky State Reserve Belarusian State University [Minsk, Bielorussie] Royal Museum for Central Africa [Tervuren] Université de Mons = University of Mons Royal Museum for Central Africa [Tervuren] Royal Belgian Institute for Natural Sciences [Belgium] Meise Botanic Garden [Belgium] Vrije Universiteit Brussel [Bruxelles] Universiteit Gent = Ghent University = Université de Gand Royal Museum for Central Africa [Tervuren] Meise Botanic Garden [Belgium] Institute for European Environmental Policy Universiteit Gent = Ghent University = Université de Gand Universiteit Antwerpen = University of Antwerp Royal Museum for Central Africa [Tervuren] Meise Botanic Garden [Belgium] Institut Royal des Sciences Naturelles de Belgique = Royal Belgian Institute of Natural Sciences Université de Mons = University of Mons Auteur indépendant Institut Royal des Sciences Naturelles de Belgique = Royal Belgian Institute of Natural Sciences Meise Botanic Garden [Belgium] Catholic University of Leuven = Katholieke Universiteit Leuven Meise Botanic Garden [Belgium] Université de Mons = University of Mons Institut Royal des Sciences Naturelles de Belgique = Royal Belgian Institute of Natural Sciences Université de Parakou = University of Parakou Ugyen Wangchuck Institute for Forests Training and Research Museo de Historia Natural ‘‘Alcide d'Orbigny’’ [Cochabamba, Bolivia] Universidad Mayor de San Simón [Cochabamba, Bolivie] Herbario Nacional de Bolivia Herbario Nacional de Bolivia Red de Investigadores en Herpetología Red de Investigadores en Herpetología Wildlife Conservation Society Univerzitet u Tuzli [Tuzla, Bosnie-Herzégovine] University of Sarajevo [Bosnia and Herzegovina] = Univerzitet u Sarajevu [Bosna i Hercegovina] = Université de Sarajevo [Bosnie-Herzégovine] University of Botswana Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] Fluminense Federal University [Niterói] Universidade Federal do Tocantins Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] Brazilian Agricultural Research Corporation = Empresa Brasileira de Pesquisa Agropecuária Genetic resources and biotechnology Universidade de Brasilia = University of Brasilia [Brasília] Universidade Federal de Viçosa [Brasil] = Federal University of Viçosa [Brazil] = Université fédérale de Viçosa [Brésil] Universidade de São Paulo = University of São Paulo Universidade de São Paulo = University of São Paulo Universidade Federal do Rio Grande do Sul [Porto Alegre – Brasil] = Federal University of Rio Grande do Sul [Porto Alegre – Brazil] Federal University of Goiás Instituto de Pesquisas Jardim Botanico do Rio de Janeiro Universidade Federal de Mato Grosso Universidade Estadual Paulista Júlio de Mesquita Filho = São Paulo State University Federal University of Amazonas Federal University of Juiz de Fora Universidade Federal do Rio Grande do Sul [Porto Alegre – Brasil] = Federal University of Rio Grande do Sul [Porto Alegre – Brazil] Universidade Estadual Paulista Júlio de Mesquita Filho = São Paulo State University Universidade Federal do Paraná [Curitiba, Brasil] = Federal University of Paraná [Curitiba, Brazil] = Université fédérale du Paraná [Curitiba, Brésil] Instituto Nacional de Pesquisas da Amazônia = National Institute of Amazonian Research Universidade Federal de São João del-Rei Universidade de São Paulo = University of São Paulo Universidade Federal de Pelotas = Federal University of Pelotas Universidade Estadual Paulista Júlio de Mesquita Filho = São Paulo State University Universidade Estadual Paulista Júlio de Mesquita Filho = São Paulo State University Universidade Federal da Paraiba / Federal University of Paraiba Federal University of Pernambuco [Recife] Mackenzie Presbyterian University [São Paulo] Federal University of São Carlos = Universidade Federal de São Carlos Univesidade Federal do Rio Grande do Norte = Federal University of Rio Grande do Norte Universidade Federal do Maranhão = Federal University of Maranhão Instituto de Pesquisas Jardim Botanico do Rio de Janeiro Universidade Estadual de Feira de Santana [Bahia]=State University of Feira de Santana Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] Federal University of São Carlos = Universidade Federal de São Carlos Federal University of São Carlos = Universidade Federal de São Carlos Museu Paraense Emílio Goeldi [Belém, Brésil] Universidade de Brasilia = University of Brasilia [Brasília] Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] Universidade de São Paulo = University of São Paulo Universidade Estadual De Santa Cruz [Brazil] Universidade de São Paulo = University of São Paulo Universidade Estadual de Campinas = University of Campinas Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] Instituto Nacional de Pesquisas da Amazônia = National Institute of Amazonian Research Universidade Estadual de Campinas = University of Campinas Museu Paraense Emílio Goeldi [Belém, Brésil] CETESB, Environmental Company of São Paulo State Instituto Nacional de Pesquisas da Amazônia = National Institute of Amazonian Research Mamirauá Institute for Sustainable Development = Instituto de Desenvolvimento Sustentavel Mamirauá Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] Universidade Federal do Rio de Janeiro [Brasil] = Federal University of Rio de Janeiro [Brazil] = Université fédérale de Rio de Janeiro [Brésil] Universidade Estadual de Maringá [Brasil] = State University of Maringá [Brazil] = Université d'État de Maringá [Brésil] Federal University of Pernambuco [Recife] Universiti Brunei Darussalam Universiti Brunei Darussalam Sofia University Saint Kliment Ohridski - Софийски университет „Свети Климент Охридски Sofia University Saint Kliment Ohridski - Софийски университет „Свети Климент Охридски Sofia University Saint Kliment Ohridski - Софийски университет „Свети Климент Охридски National Museum of Natural History [Sofia] Sofia University Saint Kliment Ohridski - Софийски университет „Свети Климент Охридски Bulgarian Academy of Sciences = Académie bulgare des sciences [Académie des sciences de Bulgarie] = Българска академия на науките Université de Douala Canadian National Collection of Insects, Arachnids, and Nematodes, Science & Technology Branch, Agriculture and Agri-Food Canada, Ottawa, ON, K1A 0C6 University of Manitoba [Winnipeg] Yukon University Université de Montréal Université de Montréal University of Alberta Canadian Museum of Nature University of Victoria [Canada] Natural Resources Canada University of Saskatchewan [Saskatoon, Canada] Canadian National Collection of Insects, Arachnids, and Nematodes, Science & Technology Branch, Agriculture and Agri-Food Canada, Ottawa, ON, K1A 0C6 Provincial Museum of Newfoundland and Labrador Canadian National Collection of Insects, Arachnids, and Nematodes, Science & Technology Branch, Agriculture and Agri-Food Canada, Ottawa, ON, K1A 0C6 Oligochaetology Laboratory, Kitchener Université de Montréal Université Laval [Québec] Royal Alberta Museum Wilfrid Laurier University Parks Canada = Parcs Canada University of British Columbia [Canada] University of Winnipeg University of Toronto Ottawa Research and Development Centre Royal Ontario Museum Ontario Ministry of Natural Resources and Forestry Universidad de Concepción = University of Concepción [Chile] Instituto de Ecología y Biodiversidad Universidad de La Serena Universidad Austral de Chile Museo Nacional de Historia Natural Chile Universidad de Concepción = University of Concepción [Chile] Centro de Estudios Avanzados en Zonas Aridas Universidad Católica de la Santísima Concepción Universidad Central de Chile Universidad Austral de Chile Nanjing Forestry University Ocean University of China Zhejiang University [Hangzhou, China] Yan'an University Kunming Institute of Zoology Kunming Institute of Zoology Zhejiang University [Hangzhou, China] Guangdong Academy of Agricultural Sciences Jiangsu Academy of Agricultural Sciences Qingdao Agricultural University The Government of the Hong Kong Special Administrative Region Institut de Systématique, Evolution, Biodiversité Mécanismes Adaptatifs et Evolution Office Pour les Insectes et leur Environnement Centre de Recherche en Paléontologie - Paris Institut méditerranéen d'océanologie Institut de Systématique, Evolution, Biodiversité Institut des Sciences de l'Evolution de Montpellier Centre de Biologie pour la Gestion des Populations Institut de Systématique, Evolution, Biodiversité Universidad de Sevilla = University of Seville = Université de Seville
• Publié dans Bioscience le 25/10/2020

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Résumé : The fundamental value of universal nomenclatural systems in biology is that they enable unambiguous scientific communication. However, the stability of these systems is threatened by recent discussions asking for a fairer nomenclature, raising the possibility of bulk revision processes for “inappropriate” names. It is evident that such proposals come from very deep feelings, but we show how they can irreparably damage the foundation of biological communication and, in turn, the sciences that depend on it. There are four essential consequences of objective codes of nomenclature: universality, stability, neutrality, and transculturality. These codes provide fair and impartial guides to the principles governing biological nomenclature and allow unambiguous universal communication in biology. Accordingly, no subjective proposals should be allowed to undermine them.

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Fichiers liés : biae043.pdf

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Source

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• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2024
• Auteurs : Romain BourcierGaultier MarnatCyril DargazanliFrançois ZhuArturo ConsoliEimad ShotarKevin PrematFrançois EugeneKevin JanotVincent L'AllinecJulien OgnardJean-Philippe DesillesRaphael BlancJean-Christophe GentricFrédéric BourdainJulien LabreucheLiang LiaoFrédéric ClarençonXavier BarreauHéloïse IferganJean-François HakBasile KerlerouxRaoul PopSébastien SoizeNicolas BricoutJildaz CaroffJohann Sebastian RichterHubert DesalBertrand LapergueAymeric RouchaudWagih BenhassenOlivier NaggaraCélia TuttleLouis VeunacAlain DuhamelRoberto RivaLili DétrazSimon EscalardLorenzo PiergalliniHocine RedjemAnthony ReyreVanessa ChalumeauNicolas PangonThomas PersonnicGrègoire BoulouisXavier CarleSolène HebertAlexis GonnetCedric LenobleBenjamin MaïerHelene RaoultLaurent Lagoarde-SegotFrederico Di MariaPierre-Louis AlexandreMatteo CappucciBenjamin GoryFlorent GarielChristophe PayaFouzi BalaMartin BretznerGéraud ForestierPierre François ManceauQuentin AliasJean Baptiste GirotImad DerrazJulien Ognard
• Organismes : Centre Hospitalier Universitaire de Nantes = Nantes University Hospital ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 Centre Hospitalier Universitaire de Bordeaux Centre Hospitalier Régional Universitaire [Montpellier] Institut de Génomique Fonctionnelle Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy] Imagerie Adaptative Diagnostique et Interventionnelle Hôpital Foch [Suresnes] Azienda Ospedaliero Universitaria Careggi [Firenze] = Careggi University Hospital [Florence, Italy] CHU Pitié-Salpêtrière [AP-HP] CHU Pitié-Salpêtrière [AP-HP] Laboratoire Traitement du Signal et de l'Image Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Service de neuroradiologie [CHRU Tours] Centre Hospitalier Universitaire d'Angers Laboratoire de Traitement de l'Information Medicale Centre Hospitalier Régional Universitaire de Brest Service de neurologie [Hôpital Fondation Adolphe de Rothschild] Service de neurologie [Hôpital Fondation Adolphe de Rothschild] Centre Hospitalier Régional Universitaire de Brest Laboratoire de Traitement de l'Information Medicale Centre Hospitalier de la Côte Basque Centre Hospitalier Régional Universitaire [CHU Lille] Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy] Imagerie Adaptative Diagnostique et Interventionnelle CHU Pitié-Salpêtrière [AP-HP] Centre Hospitalier Universitaire de Bordeaux Service de neuroradiologie [CHRU Tours] Hôpital de la Timone [CHU - APHM] Hôpital de la Timone [CHU - APHM] Département de Neuroradiologie [Strasbourg] Hôpital universitaire Robert Debré [Reims] Service de neuroradiologie [Lille] Service de Neuroradiologie [CHU de Bicêtre] Centre hospitalier de Pau Centre Hospitalier Universitaire de Nantes = Nantes University Hospital ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 Hôpital Foch [Suresnes] Université de Versailles Saint-Quentin-en-Yvelines BIO-SANTÉ Centre Hospitalier Universitaire Dupuytren 1 et 2 Université Paris Cité Département de neuroradiologie diagnostique et thérapeutique [CHRU Nancy]
• Publié dans The Lancet Neurology le 27/10/2020

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Résumé : Background: Positive susceptibility vessel sign (SVS) in patients with acute ischaemic stroke has been associated with friable red blood cell-rich clots and more effective recanalisation using stent retrievers versus contact aspiration. We compared the safety and efficacy of stent retrievers plus contact aspiration (combined technique) versus contact aspiration alone as the first-line thrombectomy technique in patients with acute ischaemic anterior circulation stroke and SVS-positive occlusions. Methods: Adaptive Endovascular Strategy to the Clot MRI in Large Intracranial Vessel Occlusion (VECTOR) was a prospective, randomised, open-label study with blinded evaluation. Patients with SVS-positive anterior circulation occlusions on pretreatment MRI and arterial puncture within 24 h of symptom onset were enrolled from 22 centres in France. A centralised web-based method was used by interventional neuroradiologists for dynamic randomisation by minimisation. Patients were randomly assigned 1:1 to the combined technique or contact aspiration alone. The primary outcome was expanded Thrombolysis in Cerebral Infarction (eTICI) grade 2c or 3 reperfusion after three or fewer passes on post-treatment angiogram, adjudicated by a blinded independent central imaging core laboratory. The intention-to-treat population was used to assess the primary and secondary outcomes. This trial is registered with ClinicalTrials.gov (NCT04139486) and is complete. Findings: Between Nov 26, 2019, and Feb 14, 2022, 526 patients were enrolled, of whom 521 constituted the intention-to-treat population (combined technique, n=263; contact aspiration alone, n=258). The median age of participants was 74·9 years (IQR 64·4-83·3); 284 (55%) were female and 237 (45%) male. The primary outcome did not differ significantly between groups (152 [58%] of 263 patients for the combined technique vs 135 [52%] of 258 for contact aspiration; odds ratio [OR] 1·27; 95% CI 0·88-1·83; p=0·19). Procedure-related adverse events occurred in 32 (12%) of 263 patients in the combined technique group and 27 (11%) of 257 in the contact aspiration group (OR 1·14; 0·65-2·00; p=0·65). The most common adverse event was intracerebral haemorrhage (146 [56%] of 259 patients for the combined technique vs 123 [49%] of 251 for contact aspiration; OR 1·32; 0·91-1·90; p=0·13). All-cause mortality at 3 months occurred in 57 (23%) of 251 patients in the combined technique group and 48 (19%) of 247 in the contact aspiration group (OR 1·19; 0·76-1·86; p=0·45), none of which was treatment-related. Interpretation: The results of the VECTOR trial do not show superiority of the combined stent retriever plus contact aspiration technique over contact aspiration alone in patients with SVS-positive occlusion with respect to achieving eTICI 2c-3 within three passes. These findings support the use of either the combined technique or contact aspiration alone as the initial thrombectomy strategy in patients with acute anterior circulation stroke with SVS on pretreatment MRI. Funding: Cerenovus.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/07/2024
• Auteurs : Thomas PerrosAnaïs Biquet-BisquertZacchari Ben MeriemMorgan DelaruePierre JosephPhilippe MarcqOlivier Cochet-Escartin
• Organismes : iLM - Biophysique iLM - Biophysique Centre de Biologie Structurale [Montpellier] Service Instrumentation Conception Caractérisation Équipe Micro-Nanofluidique pour les sciences de la vie et de l’environnement Équipe Micro-Nanofluidique pour les sciences de la vie et de l’environnement Physique et mécanique des milieux hétérogènes iLM - Biophysique
• Publié dans Biophysical Journal le 28/10/2020

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Résumé : Hydra vulgaris, long known for its remarkable regenerative capabilities, is also a long-standing source of inspiration for models of spontaneous patterning. Recently it became clear that early patterning during Hydra regeneration is an integrated mechanochemical process whereby morphogen dynamics is influenced by tissue mechanics. One roadblock to understanding Hydra self-organization is our lack of knowledge about the mechanical properties of these organisms. In this study, we combined microfluidic developments to perform parallelized microaspiration rheological experiments and numerical simulations to characterize these mechanical properties. We found three different behaviors depending on the applied stresses: an elastic response, a viscoelastic response, and tissue rupture. Using models of deformable shells, we quantify their Young’s modulus, shear viscosity, and the critical stresses required to switch between behaviors. Based on these experimental results, we propose a description of the tissue mechanics during normal regeneration. Our results provide a first step toward the development of original mechanochemical models of patterning grounded in quantitative experimental data

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Fichiers liés : BJ_resubmission_bioarxiv.pdf

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• Type de publi. : Rapport
• Date de publi. : 01/07/2024
• Auteurs : Marie-Claire PatyBénédicte ApoueyClémentine CalbaÉric CardinaleCarine MilcentDavid A RoizElodie RouviereJean-Michel SallesFrédéric SimardYannick SimoninJosselin ThuilliezLaura MaximBénédicte ApoueyLuc BaumstarkCéline BonnetThierry BrunelleFrance CaillavetAlain CarpentierThomas CoutrotCécile Detang-DessendreSerge GarciaJulien GautheyEmmanuelle LavaineMarc LeandriChristine Le ClaincheYouenn LoheacSelim LouafiEric PlottuÉlodie RouviereMaïder Saint JeanDenis SallesLouis-Georges SolerLéa TardieuJean-Christophe VergnaudGilles MeyerXavier BaillyCatherine BellocStéphane BertagnoliAlain BoissySéverine BoullierHenri-Jean BoulouisEric CardinaleAurélie CourcoulAlice de Boyer Des RochesBarbara DufourEmmanuelle Gilot-FromontÉtienne GiraudLionel GrisotClaire GuinatNadia HaddadElsa JourdainHervé JuinSophie Le Bouquin-Le NeveuCaroline Le MaréchalSophie Le PoderYves MillemannPierre MormèdeCarole PerozClaire PonsartCéline RichommeClaude SaegermanJean-François ValarcherIsabelle ValléeAgnès Waret-SzkutaNatacha Woronoff-RehnPhilippe QuénelFrédérick ArnaudThierry BaldetDaniel BleyChristophe BoeteSarah BonnetEmmanuel LienardAntoinette LudwigSylvie ManguinMarie-Claire PatyChristophe PaupyJocelyn RaudeMagalie Rene-MartelletDavid RoizClaude SaegermanFrédéric SimardJean-Paul StahlÉmeline BarrèsVéronique RaimondJohanna FiteFlorence ÉtoréKarine Fiore
• Organismes : Santé publique France - French National Public Health Agency [Saint-Maurice, France] Paris School of Economics Centre National de la Recherche Scientifique Santé publique France Provence-Alpes-Côte d'azur et Corse - Provence-Alps-French Riviera and Corsica [Marseille] Centre de Coopération Internationale en Recherche Agronomique pour le Développement Paris School of Economics Centre National de la Recherche Scientifique Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle AgroParisTech Centre National de la Recherche Scientifique Centre d'Economie de l'Environnement - Montpellier Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle Institut National de la Santé et de la Recherche Médicale Université de Montpellier Centre National de la Recherche Scientifique Université de Rennes Laboratoire Interdisciplinaire Sciences, Innovations, Sociétés Paris School of Economics Université Lumière - Lyon 2 Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Centre International de Recherche sur l'Environnement et le Développement Paris-Saclay Applied Economics Structures et Marché Agricoles, Ressources et Territoires Direction de l'animation de la recherche, des études et des statistiques Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Bureau d'Économie Théorique et Appliquée OFB Direction de la recherche et de l’appui scientifique Centre d'Economie de l'Environnement - Montpellier Université de Versailles Saint-Quentin-en-Yvelines Lille économie management - UMR 9221 Centre National de la Recherche Scientifique Université de Rennes Centre de Coopération Internationale en Recherche Agronomique pour le Développement Amélioration génétique et adaptation des plantes méditerranéennes et tropicales Université de Rennes Sciences pour l'Action et le Développement : Activités, Produits, Territoires Université de Bordeaux Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Centre d'économie de la Sorbonne École d’Économie de Paris École nationale vétérinaire de Toulouse Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique École nationale vétérinaire de Toulouse Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement École nationale vétérinaire de Toulouse Biologie moléculaire et immunologie parasitaires et fongiques Centre de Coopération Internationale en Recherche Agronomique pour le Développement Animal, Santé, Territoires, Risques et Ecosystèmes École nationale vétérinaire, agroalimentaire et de l'alimentation Nantes-Atlantique VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement École nationale vétérinaire d'Alfort VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Groupement Technique Vétérinaire Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement École nationale vétérinaire d'Alfort Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Laboratoire de Ploufragan-Plouzané-Niort [ANSES] Laboratoire de Ploufragan-Plouzané-Niort [ANSES] École nationale vétérinaire d'Alfort École nationale vétérinaire d'Alfort Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement Laboratoire de santé animale Laboratoire de la rage et de la faune sauvage de Nancy Université de Liège = University of Liège = Universiteit van Luik = Universität Lüttich Swedish University of Agricultural Sciences = Sveriges lantbruksuniversitet Biologie moléculaire et immunologie parasitaires et fongiques École nationale vétérinaire de Toulouse Laboratoire Vétérinaire Départemental du Doubs Institut de recherche en santé, environnement et travail École des Hautes Études en Santé Publique Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement Centre de Coopération Internationale en Recherche Agronomique pour le Développement Centre National de la Recherche Scientifique Institut de Recherche pour le Développement Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement École nationale vétérinaire de Toulouse Public Health Agency of Canada Institut de Recherche pour le Développement Santé publique France - French National Public Health Agency [Saint-Maurice, France] Institut de Recherche pour le Développement Université de Rennes Arènes: politique, santé publique, environnement, médias Unité des Virus Emergents École des Hautes Études en Santé Publique Département des sciences humaines et sociales Recherche sur les services et le management en santé VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement Institut de Recherche pour le Développement Fundamental and Applied Research for Animals & Health Université de Liège = University of Liège = Universiteit van Luik = Universität Lüttich Institut de Recherche pour le Développement CHU de Grenoble-Alpes - Centre Hospitalier Universitaire CHU Grenoble Direction de l'Evaluation des Risques Direction Sciences sociales, Economie et Société Direction de l'Evaluation des Risques Direction de l'Evaluation des Risques Direction Sciences sociales, Economie et Société

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Fichiers liés : ASE2022SA0146RA.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 28/06/2024
• Auteurs : Nicolas de ProstÉtienne AudureauAntoine GuillonLynda HandalaSébastien PréauAurélie GuigonFabrice UhelQuentin Le HingratFlora DelamaireClaire GrolhierFabienne TamionAlice MoisanCédric DarreauJean ThominDamien ContouAmandine HenryThomas DaixSébastien HantzClément SaccheriValerie GiordanengoTài PhamAmal ChaghouriPierre BayJean-Michel PawlotskySlim FouratiKeyvan RazaziArmand Mekontso DessapRaphaël BellaïcheLucile PicardAlexandre SoulierMélissa N’debiSarah SengChristophe RodriguezFrédéric PeneAnne-Sophie L’honneurAdrien JosephElie AzoulayMaud SalmonaMarie-Laure ChaixCharles-Edouard LuytDavid LevyJulien MayauxStéphane MarotJuliette BernierMaxime GaspermentTomas UrbinaHafid Ait-OufellaEric MauryLaurence Morand-JoubertDjeneba Bocar FofanaJean-François TimsitDelphyne DescampsGuillaume VoiriotNina de MontmollinMathieu TurpinStéphane GaudrySégolène BrichlerTài Olivier PhamElyanne GaultSébastien JochmansAurélia PitschGuillaume ChevrelCéline ClergueKubab SabahLaurence Courdavault Vagh WeinmannClaudio Garcia-SanchezFerhat MezianiLouis-Marie JandeauxSamira Fafi-KremerElodie LaugelSébastien PreauAurélie GuignonAntoine KimmounEvelyne SchvoererCedric HartardCharles DamoiselNicolas BrechotHelene PéréFrançois BeloncleFrancoise Lunel FabianiRémi CoudroyArnaud ThilleFrançois ArriveSylvain Le PapeLaura MarchassonLuc DerocheNicolas LevequeV. ThibaultBéatrice La CombeSéverine HaouiseeAlexandre BoyerSonia BurrelGaetan BeduneauChristophe GiraultMaximillien GrallDorothée CarpentierJean-Christophe PlantierEmmanuel CanetAudrey RodallecBerthe Marie ImbertSami HraeichPierre-Edouard FournierPhilippe ColsonAnaïs DartevelSylvie LarratGuillaume ThierySylvie PilletKada KloucheEdouard TuaillonCécile AubronAdissa TranSophie ValletPierre-Emmanuel CharlesAlexis Le RougemontBertrand SouweineCecile HenquellAudrey MirandBruno MourvillierLaurent AndreolettiClément LierDamien Du CheyronNefert Candace DossouAstrid VabretGaël PitonQuentin LepillerSylvie Roger
• Organismes : Service d'anesthésie-réanimation SAMU94-SMUR94 [Mondor] Groupe de recherche clinique CARMAS (Cardiovascular and Respiratory Manifestations of Acute lung injury and Sepsis) IMRB - VHC/"Viruses-Hepatology-Cancers" [Créteil] Université Paris-Est Créteil Val-de-Marne - Faculté de médecine Université Paris-Est Créteil Val-de-Marne - Faculté de médecine IMRB - CEPIA/"Clinical Epidemiology And Ageing : Geriatrics, Primary Care and Public Health" [Créteil] Hôpital Henri Mondor Centre d’Etude des Pathologies Respiratoires [Tours] Centre Hospitalier Régional Universitaire de Tours Morphogénèse et antigénicité du VIH, des Virus des Hépatites et Emergents Centre Hospitalier Régional Universitaire de Tours Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167 Centre Hospitalier Régional Universitaire [CHU Lille] Centre Hospitalier Régional Universitaire [CHU Lille] Service de Virologie [Lille] Institut Necker Enfants-Malades Hôpital Louis Mourier - AP-HP [Colombes] Infection, Anti-microbiens, Modélisation, Evolution AP-HP - Hôpital Bichat - Claude Bernard [Paris] Service des maladies infectieuses et réanimation médicale [Rennes] = Infectious Disease and Intensive Care [Rennes] Laboratoire de Virologie [Rennes] = Virology [Rennes] CHU Rouen Dynamique Microbienne associée aux Infections Urinaires et Respiratoires Laboratoire de virologie [Rouen] CHU Rouen Université de Caen Normandie Centre Hospitalier Le Mans (CH Le Mans) Centre Hospitalier Le Mans (CH Le Mans) Centre hospitalier Victor Dupouy [Centre hospitalier d'Argenteuil] Centre hospitalier Victor Dupouy [Centre hospitalier d'Argenteuil] Service de Réanimation Polyvalente [CHU Limoges] Centre d'Investigation Clinique de Limoges Anti-infectieux : supports moléculaires des résistances et innovations thérapeutiques Centre National de Référence des Herpèsvirus [Limoges] Centre Hospitalier Universitaire de Nice Caractérisation et Modélisation Multi-échelle, Multi-physique CHU Nice [Cimiez] Centre de recherche en épidémiologie et santé des populations Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre] Groupe de recherche clinique CARMAS (Cardiovascular and Respiratory Manifestations of Acute lung injury and Sepsis) Hôpital Paul Brousse Groupe de recherche clinique CARMAS (Cardiovascular and Respiratory Manifestations of Acute lung injury and Sepsis) IMRB - VHC/"Viruses-Hepatology-Cancers" [Créteil] CHU Henri Mondor [Créteil] Université Paris-Est Créteil Val-de-Marne - Paris 12 IMRB - VHC/"Viruses-Hepatology-Cancers" [Créteil] Hôpital Henri Mondor CHU Henri Mondor [Créteil] Université Paris-Est Créteil Val-de-Marne - Faculté de médecine IMRB - VHC/"Viruses-Hepatology-Cancers" [Créteil]
• Publié dans Annals of Intensive Care le 23/10/2020

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Résumé : Abstract Background A notable increase in severe cases of COVID-19, with significant hospitalizations due to the emergence and spread of JN.1 was observed worldwide in late 2023 and early 2024. However, no clinical data are available regarding critically-ill JN.1 COVID-19 infected patients. Methods The current study is a substudy of the SEVARVIR prospective multicenter observational cohort study. Patients admitted to any of the 40 participating ICUs between November 17, 2022, and January 22, 2024, were eligible for inclusion in the SEVARVIR cohort study (NCT05162508) if they met the following inclusion criteria: age ≥ 18 years, SARS-CoV-2 infection confirmed by a positive reverse transcriptase-polymerase chain reaction (RT-PCR) in nasopharyngeal swab samples, ICU admission for acute respiratory failure. The primary clinical endpoint of the study was day-28 mortality. Evaluation of the association between day-28 mortality and sublineage group was conducted by performing an exploratory multivariable logistic regression model, after systematically adjusting for predefined prognostic factors previously shown to be important confounders (i.e. obesity, immunosuppression, age and SOFA score) computing odds ratios (OR) along with their corresponding 95% confidence intervals (95% CI). Results During the study period (November 2022–January 2024) 56 JN.1- and 126 XBB-infected patients were prospectively enrolled in 40 French intensive care units. JN.1-infected patients were more likely to be obese (35.7% vs 20.8%; p = 0.033) and less frequently immunosuppressed than others (20.4% vs 41.4%; p = 0.010). JN.1-infected patients required invasive mechanical ventilation support in 29.1%, 87.5% of them received dexamethasone, 14.5% tocilizumab and none received monoclonal antibodies. Only one JN-1 infected patient (1.8%) required extracorporeal membrane oxygenation support during ICU stay (vs 0/126 in the XBB group; p = 0.30). Day-28 mortality of JN.1-infected patients was 14.6%, not significantly different from that of XBB-infected patients (22.0%; p = 0.28). In univariable logistic regression analysis and in multivariable analysis adjusting for confounders defined a priori, we found no statistically significant association between JN.1 infection and day-28 mortality (adjusted OR 1.06 95% CI (0.17;1.42); p = 0.19). There was no significant between group difference regarding duration of stay in the ICU (6.0 [3.5;11.0] vs 7.0 [4.0;14.0] days; p = 0.21). Conclusions Critically-ill patients with Omicron JN.1 infection showed a different clinical phenotype than patients infected with the earlier XBB sublineage, including more frequent obesity and less immunosuppression. Compared with XBB, JN.1 infection was not associated with higher day-28 mortality.

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• Type de publi. : Communication dans un congrès
• Date de publi. : 26/06/2024
• Auteurs : Elodie PeghaireThomas FlahautGwendoline ChristophePascal DubessayAlina-Violeta UrsuCédric DelattreLuc MarchalSébastien CholletGuillaume RoelensPedro CoutinhoNicolas TerraponR. VincentelliLaurent ChaisemartinJean-Yves BerthonPhilippe MichaudGuillaume Pierre
• Organismes : Institut Pascal Institut Pascal Institut Pascal Institut Pascal Institut Pascal Génie des Procédés, Energétique et Biosystèmes Institut Pascal Institut Pascal Institut Pascal Institut Pascal Laboratoire de génie des procédés - environnement - agroalimentaire Bioprocédés Appliqués aux Microalgues CAPACITÉS SAS CAPACITÉS SAS Architecture et fonction des macromolécules biologiques Architecture et fonction des macromolécules biologiques Architecture et fonction des macromolécules biologiques GREENTECH GREENTECH Institut Pascal Institut Pascal Institut Pascal Institut Pascal Institut Pascal

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• Type de publi. : Communication dans un congrès
• Date de publi. : 26/06/2024
• Auteurs : Philippe Jean-PierreSébastien BourdinFrançois Hermet
• Organismes : Centre d'Économie et de Management de l'Océan Indien Métis Lab EM Normandie Centre de Recherche Juridique

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