Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2007
• Auteurs : Barbara CauwelierHélène CavéCarine GervaisMichel LessardCarole BarinChristine PerotJacqueline van den AkkerFrancine MugneretChristiane CharrinMarie Pierre PagèsMarie-José GrégoirePhilippe JonveauxMarina Lafage-PochitaloffMarie Joelle MozzicconacciChristine TerréIsabelle LuquetPascale Cornillet-LefebvreBernard LaurenceGhislaine PlessisChristine LefebvreDominique LerouxHélène Antoine-PoirelCarlos GrauxLaurent MauvieuxPierre HeimannCéline ChalasEmmanuel ClappierBruno VerhasseltYves BenoitBarbara MoerlooseBruce PoppeNadine van RoyKim De KeersmaeckerJan CoolsFrançois SigauxRoland BergerJean SoulierAnne HagemeijerAnne PaepeNicole DastugueFranck Speleman
• Organismes : Center for Medical Genetics [Ghent] Laboratoire de Biochimie Génétique Laboratoire d'Hématologie Laboratoire d'Hématologie CHU Bretonneau Centre de Recherche Saint-Antoine Centre de Recherche Saint-Antoine Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand Laboratoire Central d'Anatomie et de Cytologie Pathologiques [Hôpital Edouard Herriot - HCL] Laboratoire Central d'Anatomie et de Cytologie Pathologiques [Hôpital Edouard Herriot - HCL] Service de Génétique [CHRU Nancy] Service de Génétique [CHRU Nancy] Institut Paoli-Calmettes Institut Paoli-Calmettes Centre Hospitalier de Versailles André Mignot Hôpital Maison Blanche Hôpital Maison Blanche Hôpital Robert Debré Service de Génétique [CHU Caen] Bases moléculaires de la progression tumorale -Groupe de Recherche sur les Lymphomes Bases moléculaires de la progression tumorale -Groupe de Recherche sur les Lymphomes Centre for Medical genetics Gvh et Gvl : Physiopathologie Chez l'Homme et Chez l'Animal, Incidence et Role Therapeutique Laboratoire d'Hématologie Department of Medical Genetics Laboratoire de Biochimie Génétique CHU Bretonneau Centre for Molecular Diagnostics Department of Pediatric Hematology/Oncology Department of Pediatric Hematology/Oncology Center for Medical Genetics [Ghent] Center for Medical Genetics [Ghent] Department of Human Genetics Department of Human Genetics Gvh et Gvl : Physiopathologie Chez l'Homme et Chez l'Animal, Incidence et Role Therapeutique Hôpital Necker - Enfants Malades [AP-HP] Gvh et Gvl : Physiopathologie Chez l'Homme et Chez l'Animal, Incidence et Role Therapeutique Centre for Human Genetics Center for Medical Genetics [Ghent] Service Hématologie - IUCT-Oncopole [CHU Toulouse] Center for Medical Genetics [Ghent]
• Publié dans Leukemia le 25/10/2020

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Résumé : Recently, we and others described a new chromosomal rearrangement, that is, inv(7)(p15q34) and t(7;7)(p15;q34) involving the T-cell receptor beta (TCRbeta) (7q34) and the HOXA gene locus (7p15) in 5% of T-cell acute lymphoblastic leukemia (T-ALL) patients leading to transcriptional activation of especially HOXA10. To further address the clinical, immunophenotypical and molecular genetic findings of this chromosomal aberration, we studied 330 additional T-ALLs. This revealed TCRbeta-HOXA rearrangements in five additional patients, which brings the total to 14 cases in 424 patients (3.3%). Real-time quantitative PCR analysis for HOXA10 gene expression was performed in 170 T-ALL patients and detected HOXA10 overexpression in 25.2% of cases including all the cases with a TCRbeta-HOXA rearrangement (8.2%). In contrast, expression of the short HOXA10 transcript, HOXA10b, was almost exclusively found in the TCRbeta-HOXA rearranged cases, suggesting a specific role for the HOXA10b short transcript in TCRbeta-HOXA-mediated oncogenesis. Other molecular and/or cytogenetic aberrations frequently found in subtypes of T-ALL (SIL-TAL1, CALM-AF10, HOX11, HOX11L2) were not detected in the TCRbeta-HOXA rearranged cases except for deletion 9p21 and NOTCH1 activating mutations, which were present in 64 and 67%, respectively. In conclusion, this study defines TCRbeta-HOXA rearranged T-ALLs as a distinct cytogenetic subgroup by clinical, immunophenotypical and molecular genetic characteristics.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2007
• Auteurs : Christelle M. DurandCatalina BetancurTobias M. BoeckersJuergen BockmannPauline ChasteFabien FauchereauGudrun NygrenMaria RastamI Carina GillbergHenrik AnckarsäterEili SponheimHany Goubran-BotrosRichard DelormeNadia ChabaneMarie-Christine Mouren-SimeoniPhilippe de MasEric BiethBernadette RogéDelphine HéronLydie BurglenChristopher GillbergMarion LeboyerThomas Bourgeron
• Organismes : Génétique Humaine et Fonctions Cognitives Neurobiologie et Psychiatrie Institute for Anatomy and Cell Biology Institute for Anatomy and Cell Biology Génétique Humaine et Fonctions Cognitives Génétique Humaine et Fonctions Cognitives Université Paris Diderot - Paris 7 Department of Child and Adolescent Psychiatry Department of Child and Adolescent Psychiatry Department of Child and Adolescent Psychiatry Department of Child and Adolescent Psychiatry Centre for Child and Adolescent Psychiatry Génétique Humaine et Fonctions Cognitives Génétique Humaine et Fonctions Cognitives Service de psychopathologie de l'enfant et de l'adolescent Service de psychopathologie de l'enfant et de l'adolescent Department of Medical Genetics Department of Medical Genetics Centre d'études et de recherches en psychopathologie CHU Pitié-Salpêtrière [AP-HP] CHU Trousseau [APHP] Department of Child and Adolescent Psychiatry Saint George's Hospital Medical School Neurobiologie et Psychiatrie Département de Psychiatrie Génétique Humaine et Fonctions Cognitives Université Paris Diderot - Paris 7
• Publié dans Nature Genetics le 29/10/2020

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Résumé : SHANK3 (also known as ProSAP2) regulates the structural organization of dendritic spines and is a binding partner of neuroligins; genes encoding neuroligins are mutated in autism and Asperger syndrome. Here, we report that a mutation of a single copy of SHANK3 on chromosome 22q13 can result in language and/or social communication disorders. These mutations concern only a small number of individuals, but they shed light on one gene dosage-sensitive synaptic pathway that is involved in autism spectrum disorders.

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Fichiers liés : Durand_SHANK3_Nat_Genet_2007.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2007
• Auteurs : Jean-Philippe BorgesAnnick BarreRaphael CulerrierNicolas ArchimbaudAlain DidierPierre Rougé
• Organismes : Centre de Recherche en Sciences et Technologies de l'Information et de la Communication - EA 3804 Centre de Recherche en Acquisition et Traitement de l'Image pour la Santé Modeling & analysis for medical imaging and Diagnosis
• Publié dans Biochimie le 28/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2007
• Auteurs : Philippe LasayguesRégine GuillerminJean-Pierre Lefebvre
• Organismes : Laboratoire de Mécanique et d'Acoustique [Marseille] Laboratoire de Mécanique et d'Acoustique [Marseille] Laboratoire de Mécanique et d'Acoustique [Marseille]
• Publié dans Ultrasonic Imaging le 25/10/2020

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Résumé : This study focuses on the application of ultrasonic diffraction tomography to noncircular 2D-cylindrical objects immersed in an infinite fluid. The distorted Born iterative method used to solve the inverse scattering problem be longs to the class of algebraic reconstruction algorithms. This method was developed to increase the order of application of the Born approximation (in the case of weakly-contrasted media) to higher orders. This yields quantitative in formation about the scatterer, such as the speed of sound and the attenuation. Quantitative ultrasonic imaging techniques of this kind are of great potential value in fields such as medicine, under water acoustics and non destructive testing.

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Fichiers liés : Lasaygues_V3.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2007
• Auteurs : Philippe WaldteufelPhilippe RichaumeYann H. KerrWigneron J.-P.Ali MahmoodiArnaud MialonJ.-L. VergelyFrançois CabotPaolo FerrazzoliSteven Delwart
• Organismes : Service d'aéronomie Centre d'études spatiales de la biosphère Centre d'études spatiales de la biosphère Écologie fonctionnelle et physique de l'environnement Array Systems Computing Centre d'études spatiales de la biosphère Analytic and Computational Research, Inc. - Earth Sciences Centre d'études spatiales de la biosphère Università degli Studi di Roma Tor Vergata [Roma, Italia] = University of Rome Tor Vergata [Rome, Italy] = Université de Rome Tor Vergata [Rome, Italie] European Space Research and Technology Centre

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Résumé : This contribution summarizes prominent features of the Level 2 algorithm aimed at processing land surface geophysical quantities from the ESA-led SMOS mission. It emphasizes the soil moisture retrieval and describes the decision tree built in order to select appropriate retrieval configurations. The expected performance is illustrated by preliminary results of the algorithm validation.

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• Type de publi. : Chapître d'ouvrage
• Date de publi. : 01/01/2007
• Auteurs : Jean-Pierre ChauveauJean-Philippe Colin
• Organismes : Marchés, Organisations, Institutions et Stratégies d'Acteurs Institut de Recherche pour le Développement Marchés, Organisations, Institutions et Stratégies d'Acteurs Institut de Recherche pour le Développement

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Résumé : This chapter studies changes in institutional arrangements for the transfer of land rights, both between groups and between individuals, in Benin, Burkina Faso, Ivory Coast and Mali. Mechanisms for the transfer of land rights range from short-term to permanent transfers, from partial to complete transfers, and from nonmonetarised arrangements embedded in social relations to market transactions. The chapter documents both changes in “customary”, non-monetarised arrangements (namely the tutorat” relationship); and the emergence of monetarised transactions, particularly land sales. While, conceptually, clear differences exist between “tutorat” arrangements (in which land transfers are embedded within a broader socio-political relationship and entail a continuing duty of gratitude and of allegiance toward the customary land holders) and sales (which are monetarised deals that do not entail a continuing relationship once the transaction is completed), in practice boundaries may be blurred, as tutorat arrangements are becoming monetarised and market transactions are nonetheless embedded in social relations.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2007
• Auteurs : Éric DuchaudMekki BoussahaValentin LouxJean-François BernardetChristian MichelBrigitte KerouaultStanislas MondotPierre P. NicolasRobert BossyChristophe C. CaronPhilippe BessièresJean-François GibratStéphane ClaverolFabien DumetzMichel Le HénafAbdenour A. Benmansour
• Organismes : Unité de recherche Virologie et Immunologie Moléculaires Unité de recherche Virologie et Immunologie Moléculaires Unité Mathématique Informatique et Génome Unité de recherche Virologie et Immunologie Moléculaires Unité de recherche Virologie et Immunologie Moléculaires Unité de recherche Virologie et Immunologie Moléculaires Unité de recherche Virologie et Immunologie Moléculaires Unité Mathématique Informatique et Génome Unité Mathématique Informatique et Génome Unité Mathématique Informatique et Génome Unité Mathématique Informatique et Génome Unité Mathématique Informatique et Génome Plateforme génomique fonctionnelle École Nationale d'Ingénieurs des Travaux Agricoles - Bordeaux École Nationale d'Ingénieurs des Travaux Agricoles - Bordeaux Unité de recherche Virologie et Immunologie Moléculaires
• Publié dans Nature Biotechnology le 29/10/2020

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Résumé : We report here the complete genome sequence of the virulent strain JIP02/86 (ATCC 49511) of Flavobacterium psychrophilum, a widely distributed pathogen of wild and cultured salmonid fish. The genome consists of a 2,861,988–base pair (bp) circular chromosome with 2,432 predicted protein-coding genes. Among these predicted proteins, stress response mediators, gliding motility proteins, adhesins and many putative secreted proteases are probably involved in colonization, invasion and destruction of the host tissues. The genome sequence provides the basis for explaining the relationships of the pathogen to the host and opens new perspectives for the development of more efficient disease control strategies. It also allows for a better understanding of the physiology and evolution of a significant representative of the family Flavobacteriaceae, whose members are associated with an interesting diversity of lifestyles and habitats

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2007
• Auteurs : Sébastien CouvreurCatherine HurtaudPierre-Guy MarnetPhilippe FaverdinJean-Louis J.-L. Peyraud
• Organismes : Production du lait Ecole Supérieure des Agricultures Production du lait Production du lait Production du lait Production du lait
• Publié dans Journal of Dairy Science le 22/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2007
• Auteurs : A. EzzhaouaniC. ValancognePhilippe PieriT. AmalakJean-Pierre J.-P. Gaudillere
• Organismes : Institut Agronomique et Vétérinaire Hassan II Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Institut Agronomique et Vétérinaire Hassan II Ecophysiologie et Génomique Fonctionnelle de la Vigne
• Publié dans Journal International des Sciences de la Vigne et du Vin le 28/10/2020

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Résumé : Aims: A study was conducted to compare traditional vineyard irrigation (TI) using one drip emitter per vine, and partial root zone drying irrigation (PRD) using two drip emitters per vine (one per each vine side), at 2 rates of water application (controlled deficit (TI4 and PRD4) and non limiting (TI8 and PRD8)). Methods and results: Individual vine transpiration and vine water status were estimated from sap flow measurements by a stem heat balance method and midday stem water potential. The quality of the harvest was not significantly changed by the treatments. However, the vegetative growth was lower for the low irrigation rate treatments (TI4 and PRD4) and the PRD8 (compared to TI8). The total amount of water transpired by the vines during the season was estimated to 147 l/m2 without water limitation. A limiting water supply (TI4) lessened vine water use and improved the fraction of supplied water trapped by the vines (81 % for TI4 and 66 % for TI8). PRD decreased the transpiration of the vines, but also the efficiency of use of irrigation water. Significance and impact of study: Limited water supply saved water and improved the water capture efficiency by the roots of the vines. PRD irrigation saved water but the vine water capture efficiency was lower, limiting the practical interest of the method.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2007
• Auteurs : Hélène GilbertJean Pierre BidanelJoseph GruandJean-Claude CaritezYvon BillonPhilippe P. GuillouetHervé LagantJean NobletPierre P. Sellier
• Organismes : Station de Génétique Quantitative et Appliquée Station de Génétique Quantitative et Appliquée Génétique Expérimentale en Productions Animales Génétique Expérimentale en Productions Animales Génétique Expérimentale en Productions Animales Insémination Caprine et Porcine Station de Génétique Quantitative et Appliquée Systèmes d'Elevage, Nutrition Animale et Humaine Station de Génétique Quantitative et Appliquée
• Publié dans Journal of Animal Science le 02/11/2020

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