Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2006
• Auteurs : Laurence Goux-CapesArianna FiloramoDenis CôteJean-Philippe BourgoinJean-Noël Patillon
• Organismes : Laboratoire d'Electronique Moléculaire Laboratoire d'Electronique Moléculaire Laboratoire Pierre Aigrain Laboratoire d'Electronique Moléculaire Laboratoire d'Electronique Moléculaire
• Publié dans Physica Status Solidi A (applications and materials science) le 25/10/2020

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Résumé : We present a simple and versatile method for linking single wall carbon nanotubes (SWNT) together through DNA by non-covalent chemistry using streptavidin-biotin recognition complex. Streptavidin coated SWNTs are reacted with biotin or bis-biotin ended DNA double strands leading to SWNT-DNA and SWNT-DNA-SWNT adducts in high yield. This method avoids strong acidic treatment of SWNTs prior to functionalization as usually required in covalent routes. Complementary characterizations by gel electrophoresis and AFM demonstrated the efficiency of the present binding method. In addition, SWNTs bound to DNA can be aligned on a substrate using the combing properties of DNA strands, bringing a new tool into the toolkit for self-assembling SWNTs onto surfaces.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2006
• Auteurs : George FlynnPierre BleuetJanet BorgJohn BradleyFrank BrenkerSean BrennanJohn BridgesDon BrownleeEmma . BullockManfred BurghammerBenton ClarkZu Rong DaiCharles DaghlianZahia DjouadiSirine FakraTristan FerroirChristine FlossIan FranchiZack GainsforthJean-Paul GallienPhilippe GilletPatrick GrantGiles GrahamSimon GreenFaustine GrossemyPhilipp HeckGregory HerzogPeter HoppeFriedrich HörzJoachim HuthKonstantin IgnatyevHope IshiiKoen JanssensDavid JoswiakAnton KearsleyHicham KhodjaAntonio LanzirottiJan LeitnerLaurence LemelleHugues LerouxKatharina LueningGlenn MacphersonKuljeet MarhasMatthew A. MarcusGraciela MatrajtTomoki NakamuraKeiko Nakamura-MessengerTsukasa NakanoMatthew NewvilleDimitri PapanastassiouPiero PianettaWilliam RaoChristian RiekelFrans RietmeijerDetlef RostCraig SchwandtThomas SeeJulie Sheffield-ParkerAlexandre SimionoviciIlona SitnitskyChristopher SneadFrank StadermannThomas StephanRhonda StroudJean SusiniYoshio SuzukiStephen SuttonSusan M. TaylorNick TeslichDavid TroadecPeter TsouAkira TsuchiyamaKentaro UesugiBart VekemansEdward VicenziLaszlo VinczeAndrew WestphalPenelope WozniakiewiczErnst ZinnerMichael Zolensky
• Organismes : European Synchrotron Radiation Facility Advanced Light Source [LBNL Berkeley] Laboratoire de Sciences de la Terre Laboratoire de Sciences de la Terre Institut d'astrophysique spatiale Laboratoire de Sciences de la Terre Advanced Light Source [LBNL Berkeley] European Synchrotron Radiation Facility Laboratoire de Sciences de la Terre European Synchrotron Radiation Facility Institut d’Électronique, de Microélectronique et de Nanotechnologie - UMR 8520
• Publié dans Science le 22/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2006
• Auteurs : Sébastien JudéSébastien RogerEric MartelPierre BessonSerge RichardPhilippe BougnouxPascal ChamperouxJean-Yves Le Guennec
• Organismes : Centre de Recherches Biologiques Niche, Nutrition, Cancer et métabolisme oxydatif Centre de Recherches Biologiques Niche, Nutrition, Cancer et métabolisme oxydatif Centre de Recherches Biologiques Niche, Nutrition, Cancer et métabolisme oxydatif Centre de Recherches Biologiques Niche, Nutrition, Cancer et métabolisme oxydatif
• Publié dans Progress in Biophysics and Molecular Biology le 25/10/2020

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Résumé : The relationship between high fish consumption and low mortality following coronary heart disease (CHD) and low incidence of breast cancer was first mentioned 3 decades ago. The fishes of interest are rich in omega-3 long-chain polyunsaturated fatty acids (omega-3 LC-PUFAs), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which could be the active nutrients. The current consensus about cardioprotection is that omega-3 LC-PUFAs would mainly exert antiarrhythmic effects. One of the proposed mechanisms is that circulating non-esterified LC-PUFAs partition into cardiac cells membrane phospholipids and exert a direct effect on ionic channels and/or modify intracellular calcium homeostasis. In another hypothesis, changes in the metabolism of phosphoinositides would be involved and lead to the differential activation of PKC isoforms. As compared to the mechanisms proposed for the cardioprotective effects of omega-3 LC-PUFAs, less is known about the molecular mechanisms involved in breast cancers prevention. Some proposed mechanisms such as the modulation of phosphoinositides metabolism and/or modulation of intracellular calcium homeostasis, are common to both pathologies. Other hypotheses involve the alteration of the cellular redox status induced by highly peroxidizable polyunsaturated fatty acids (FA), or the modulation of gene expression, both phenomena being tightly linked to apoptosis. In this review, we report and compare some proposed mechanisms for the involvement of omega-3 LC-PUFAs in both cardiac and breast cancer protection. Deliberately, we chose to discuss only the mechanisms, which are less described in other reviews such as ionic channels in cancer, calcium homeostasis, PKC activation or matrix metalloproteinases in both cancer and cardiac models. The leitmotiv along this review is that cardio- and cancero-protective effects use common pathways. Comparison of the cellular effects might therefore help to highlight the "protective" pathways.

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Fichiers liés : Jude_et_al_rev1.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2006
• Auteurs : M. FajardoPhilippe ZeitounGabriel FaivreStéphane SebbanT. MocekA. HallouD. AubertPh. BalcouF. BurgyD. DouilletPascal MercereAnne-Sophie MorlensJean-Philippe RousseauC. ValentinSophie KazamiasG. De Lachèze-MurelT. LefrouHamed MerdjiS. Le PapeMarie-Françoise Ravet-KrillFranck DelmotteJulien Gautier
• Organismes : Centro de Física dos Plasmas Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Imagine Optic Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'Optique Appliquée Laboratoire d'interaction du rayonnement X avec la matière Département de Physique Théorique et Appliquée Laboratoire pour l'utilisation des lasers intenses DAM Île-de-France Laboratoire pour l'utilisation des lasers intenses Laboratoire Charles Fabry de l'Institut d'Optique / Scop Laboratoire Charles Fabry de l'Institut d'Optique / Scop Laboratoire Charles Fabry de l'Institut d'Optique / Scop
• Publié dans Journal of Quantitative Spectroscopy and Radiative Transfer le 26/10/2020

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Résumé : High harmonic amplification is shown in an optical-field ionized X-ray laser. The 4d-4p X-ray line of Kr8+ at 32.8 nm, which has a close match to the 25th harmonic of the infrared laser, was amplified up to 200 times. The energy-extraction regime was also achieved, which depended on the level of seeding. This second-generation X-ray laser is fully polarized, has low divergence and shows a high degree of coherence. The duration is also expected to be short, fulfilling the requirements for an ultra-intense tabletop X-ray laser. Conditions for higher energy output are also suggested.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2006
• Auteurs : Jean-Philippe SteyerOlivier BernardDamien John BatstoneIrini Angelidaki
• Organismes : Laboratoire de Biotechnologie de l'Environnement [Narbonne] Modeling and control of renewable resources Danmarks Tekniske Universitet = Technical University of Denmark Danmarks Tekniske Universitet = Technical University of Denmark
• Publié dans Water Science and Technology le 26/10/2020

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Résumé : Anaerobic digestion plants are highly efficient wastewater treatment processes with inherent energy production. Despite these advantages, many industries are still reluctant to use them because of their instability confronted with changes in operating conditions. There is therefore great potential for application of instrumentation, control and automation (ICA) in the field of anaerobic digestion. This paper will discuss the requirements (in terms of on-line sensors needed, modelling efforts and mathematical complexity) but also the advantages and drawbacks of different control strategies that have been applied to AD high rate processes over the last 15 years.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2006
• Auteurs : Fabienne LaugerettePatricia Passilly-DegraceBruno PatrisIsabelle NiotJean-Pierre MontmayeurPhilippe Besnard
• Organismes : Centre des Sciences du Goût Centre des Sciences du Goût Centre des Sciences du Goût Centre des Sciences du Goût Centre des Sciences du Goût Centre des Sciences du Goût
• Publié dans Médecine/Sciences le 25/10/2020

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• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2006
• Auteurs : Jean-Philippe PerninAnne Lejeune
• Organismes : Modèles et Technologies pour l’Apprentissage Humain Modèles et Technologies pour l’Apprentissage Humain

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Résumé : no abstract

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• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2006
• Auteurs : Alice BerthelotIvan FaveroGuillaume CassaboisChristophe VoisinClaude DelalandePhilippe RoussignolJ.-M. Gérard
• Organismes : Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Nanophysique et Semiconducteurs

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2006
• Auteurs : Aude PicardPhilippe OgerIsabelle DanielHervé CardonGilles MontagnacJean-Claude Chervin
• Organismes : Laboratoire de Sciences de la Terre Laboratoire de Sciences de la Terre Laboratoire de Sciences de la Terre Laboratoire de Sciences de la Terre Laboratoire de Sciences de la Terre Institut de minéralogie et de physique des milieux condensés
• Publié dans Journal of Applied Physics le 02/11/2020

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Résumé : We present an optical pressure sensor suitable for experiments in diamond anvil cell in the 0.1 MPa–2 GPa pressure range, for temperatures between ambient and 323 K. It is based on the pressure-dependent fluorescence spectrum of FluoSpheres®, which are commercially available fluorescent microspheres commonly used to measure blood flow in experimental biology. The fluorescence of microspheres is excited by the 514.5 nm line of an Ar+ laser, and the resulting spectrum displays three very intense broad bands at 534, 558, and 598 nm, respectively. The reference wavelength and pressure gauge is that of the first inflection point of the spectrum, located at 525.6±0.2 nm at ambient pressure. It is characterized by an instantaneous and large linear pressure shift of 9.93(±0.08) nm/GPa. The fluorescence of the FluoSpheres® has been investigated as a function of pressure (0.1–4 GPa), temperature (295–343 K), pH (3–12), salinity, and pressure transmitting medium. These measurements show that, for pressures comprised between 0.1 MPa and 2 GPa, at temperatures not exceeding 323 K, at any pH, in aqueous pressure transmitting media, pressure can be calculated from the wavelength shift of two to three beads, according to the relation P=0.100 (±0.001) Deltalambdai(P) with Deltalambdai(P)=lambdai(P)–lambdai(0) and lambdai(P) as the wavelength of the first inflection point of the spectrum at the pressure P. This pressure sensor is approximately thirty times more sensitive than the ruby scale and responds instantaneously to pressure variations.

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• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2006
• Auteurs : Jean-Philippe PerninAnne Lejeune
• Organismes : Modèles et Technologies pour l’Apprentissage Humain Modèles et Technologies pour l’Apprentissage Humain

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Résumé : no abstract

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