Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : Victor Alcaraz-GonzalezRodolfo Salazar-PenaVictor Gonzalez-AlvarezJean-Luc GouzéJean-Philippe Steyer
• Organismes : Departamento de Ingeniería Química [Guadalajara] Departamento de Ingeniería Química [Guadalajara] Departamento de Ingeniería Química [Guadalajara] Modeling and control of renewable resources Laboratoire de Biotechnologie de l'Environnement [Narbonne]
• Publié dans Comptes Rendus. Biologies le 22/10/2020

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Résumé : This paper presents a robust nonlinear asymptotic observer with adjustable convergence rate with a great potential of applicability for biological systems in which the main state variables are difficult and expensive to measure or such measurements do not exist. This observer scheme is based on the classical asymptotic observer, which is modified to allow the tuning of the convergence rate. It is shown that the proposed observer provides fast and satisfactory estimates when facing load disturbances, system failures and parameter uncertainty while maintaining the excellent robustness and stability properties of the classical asymptotic observer. The implementation of the tunable observer is carried out by numerical simulations of a mathematical model of an anaerobic digestion process used for wastewater treatment. The key results are examined and further developed. (c) 2004 Academie des sciences. Published by Elsevier SAS. All rights reserved.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : Sébastien MichaudNicolas BernetPierre BuffièreJean-Philippe Delgenès
• Organismes : Laboratoire de Biotechnologie de l'Environnement [Narbonne] Laboratoire de Biotechnologie de l'Environnement [Narbonne] Laboratoire de Biotechnologie de l'Environnement [Narbonne] Laboratoire de Biotechnologie de l'Environnement [Narbonne]
• Publié dans Process Biochemistry le 25/10/2020

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Résumé : Methane yield (Y-CH4) is the result of the balance between the flows of organic carbon to catabolism and anabolism in methanogenic ecosystems. In anaerobic biofilm processes, it can be easily obtained to be used to characterize the behaviour of the biofilm in important transient phases. Thus, at the beginning of the start-up period, Y-CH4 is very low, indicating an important anabolic activity of the microorganisms to build the biofilm. Then, its value increases upto a stable level corresponding to the end of the biofilm formation. The time course of Y-CH4 describes the three phases of biofilm formation with the induction, the growth and the steady state. Therefore, it is possible to compare different start-up strategies and define the best operating conditions to grow the methanogenic biofilm. In steady state operations, Y-CH4 expresses the balance of the dynamic system between the net growth of the fixed cells and the biomass detachment, depending on the shear stress and on the capacity of the solid support to retain biomass. It also reflects the detachment rate evolution in anaerobic fixed film processes. © 2005 Elsevier Ltd. All rights reserved

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : Philippe P. GuesnetJean Marc J. M. AlessandriPierre AstorgFabien PifferiMonique Lavialle
• Organismes : Laboratoire de nutrition et sécurité alimentaire Laboratoire de nutrition et sécurité alimentaire Unité de Recherche en Epidémiologie Nutritionnelle Laboratoire de nutrition et sécurité alimentaire Laboratoire de nutrition et sécurité alimentaire
• Publié dans Oléagineux, Corps Gras, Lipides le 30/10/2020

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• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2005
• Auteurs : Lise Crevier-BuchmanPhilippe DejonckereJean-Pierre MartensMieke MoermanVirginie Woisard
• Organismes : LPP - Laboratoire de Phonétique et Phonologie - UMR 7018 Hôpital Européen Georges Pompidou [APHP]

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : Pierre-Yves BondiauGrégoire MalandainStéphane ChanaletPierre-Yves MarcyJean-Louis HabrandFrançois FauchonPhilippe PaquisAdel CourdiOlivier CommowickIsabelle RuttenNicholas Ayache
• Organismes : Medical imaging and robotics Centre de Lutte contre le Cancer Antoine Lacassagne [Nice] Medical imaging and robotics Analysis and Simulation of Biomedical Images Analysis and Simulation of Biomedical Images Computational Radiology Laboratory [Boston] Vision, Action et Gestion d'informations en Santé Medical imaging and robotics Analysis and Simulation of Biomedical Images
• Publié dans International Journal of Radiation Oncology, Biology, Physics le 31/10/2020

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Résumé : PURPOSE: Brain tumor radiotherapy requires the volume measurements and the localization of several individual brain structures. Any tool that can assist the physician to perform the delineation would then be of great help. Among segmentation methods, those that are atlas-based are appealing because they are able to segment several structures simultaneously, while preserving the anatomy topology. This study aims to evaluate such a method in a clinical context. METHODS AND MATERIALS: The brain atlas is made of two three-dimensional (3D) volumes: the first is an artificial 3D magnetic resonance imaging (MRI); the second consists of the segmented structures in this artificial MRI. The elastic registration of the artificial 3D MRI against a patient 3D MRI dataset yields an elastic transformation that can be applied to the labeled image. The elastic transformation is obtained by minimizing the sum of the square differences of the image intensities and derived from the optical flow principle. This automatic delineation (AD) enables the mapping of the segmented structures onto the patient MRI. Parameters of the AD have been optimized on a set of 20 patients. Results are obtained on a series of 6 patients' MRI. A comprehensive validation of the AD has been conducted on performance of atlas-based segmentation in a clinical context with volume, position, sensitivity, and specificity that are compared by a panel of seven experimented physicians for the brain tumor treatments. RESULTS: Expert interobserver volume variability ranged from 16.70 cm(3) to 41.26 cm(3). For patients, the ratio of minimal to maximal volume ranged from 48% to 70%. Median volume varied from 19.47 cm(3) to 27.66 cm(3) and volume of the brainstem calculated by AD varied from 17.75 cm(3) to 24.54 cm(3). Medians of experts ranged, respectively, for sensitivity and specificity, from 0.75 to 0.98 and from 0.85 to 0.99. Median of AD were, respectively, 0.77 and 0.97. Mean of experts ranged, respectively, from 0.78 to 0.97 and from 0.86 to 0.99. Mean of AD were, respectively, 0.76 and 0.97. CONCLUSIONS: Results demonstrate that the method is repeatable, provides a good trade-off between accuracy and robustness, and leads to reproducible segmentation and labeling. These results can be improved by enriching the atlas with the rough information of tumor or by using different laws of deformation for the different structures. Qualitative results also suggest that this method can be used for automatic segmentation of other organs such as neck, thorax, abdomen, pelvis, and limbs.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : Pierre MahéNobuhisa UedaTatsuya AkutsuJean-Luc PerretJean-Philippe Vert
• Organismes : Centre de Bioinformatique Centre de Bioinformatique
• Publié dans Journal of Chemical Information and Modeling le 27/10/2020

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Résumé : The support vector machine algorithm together with graph kernel functions has recently been introduced to model structure-activity relationships (SAR) of molecules from their 2D structure, without the need for explicit molecular descriptor computation. We propose two extensions to this approach with the double goal to reduce the computational burden associated with the model and to enhance its predictive accuracy: description of the molecules by a Morgan index process and definition of a second-order Markov model for random walks on 2D structures. Experiments on two mutagenicity data sets validate the proposed extensions, making this approach a possible complementary alternative to other modeling strategies.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : David BessonOlivier ParizeJean-Loup RubinoJean-Pierre AguilarMarie-Pierre AubryBernard BeaudoinWilliam A. BerggrenGeorges ClauzonPhilippe CrumeyrolleYann DexcotéNicolas FietSilvia IaccarinoGonzalo Jiménez-MorenoCécile Laporte-GalaaJacques MichauxKatharina von SalisJean-Pierre SucJean-Yves ReynaudRoland Wernli
• Organismes : Centre de Géotechnique et d'exploitation du sous sol Centre de Géotechnique et d'exploitation du sous sol Total, CST JF–TG/ISS Institut des Sciences de l'Evolution de Montpellier Centre de Géotechnique et d'exploitation du sous sol Total, CST JF–TG/ISS Centre de Géotechnique et d'exploitation du sous sol PaleoEnvironnements et PaleobioSphere Total, CST JF–TG/ISS Institut des Sciences de l'Evolution de Montpellier PaleoEnvironnements et PaleobioSphere
• Publié dans Comptes Rendus. Géoscience le 29/07/2021

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Résumé : An integrated study combining facies analysis, multiple group biostratigraphy, identification of depositional sequences and mapping has been conducted on the Miocene Molasse Basin of the external Alps (southeastern France). The filling of the basin is described as resulting from a succession of fluvial incisions subsequently filled during marine transgressions. The major incision is dated as Latest Burdigalian and the major transgression as Langhian. This revised interpretation of the Miocene physiographic evolution of the Molasse Basin implies a re-examination of previous stratigraphic correlations within the basin

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : Michael KüppersIvano BertiniSonia FornasierPedro J. GutiérrezStubbe F. HviidL. JordaHorst Uwe KellerJörg KnollenbergDetlef KoschnyRainer KrammLuisa-Maria LaraHolger SierksNicolas ThomasCesare BarbieriPhilippe LamyHans RickmanRafael RodrigoMichael F. A'HearnF. AngrilliM.E. BaileyP. BartholMaria Antonietta BarucciJean-Loup BertauxJ.A. BurnsGabriele CremoneseW. CurdtM. de CeccoS. DebeiM. FulleF. GliemW.-H. IpEkkehard KührtA. LlebariaJ.J. Lopez MorenoF. MarzariG. NalettoL. SabauA. Sanz AndrésJ.P. SivanG. TondelloK.-P. Wenzel
• Organismes : Max-Planck-Institut für Sonnensystemforschung = Max Planck Institute for Solar System Research Dipartimento di Astronomia [Padova] Dipartimento di Astronomia [Padova] Max-Planck-Institut für Sonnensystemforschung = Max Planck Institute for Solar System Research Laboratoire d'Astrophysique de Marseille Max-Planck-Institut für Sonnensystemforschung = Max Planck Institute for Solar System Research DLR Institut für Planetenforschung Max-Planck-Institut für Sonnensystemforschung = Max Planck Institute for Solar System Research Instituto de Astrofísica de Andalucía = Institute of Astrophysics of Andalusia Max-Planck-Institut für Sonnensystemforschung = Max Planck Institute for Solar System Research Dipartimento di Astronomia [Padova] Laboratoire d'Astrophysique de Marseille Uppsala Astronomical 0bservatory Instituto de Astrofísica de Andalucía = Institute of Astrophysics of Andalusia Service d'aéronomie
• Publié dans Nature le 29/10/2020

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Résumé : Comets spend most of their life in a low-temperature environment far from the Sun. They are therefore relatively unprocessed and maintain information about the formation conditions of the planetary system, but the structure and composition of their nuclei are poorly understood. Although in situ and remote measurements have derived the global properties of some cometary nuclei, little is known about their interiors. The Deep Impact mission shot a projectile into comet 9P/Tempel 1 in order to investigate its interior. Here we report the water vapour content (1.5 Å~ 1032 water molecules or 4.5 Å~ 106kg) and the cross-section of the dust (330km2 assuming an albedo of 0.1) created by the impact. The corresponding dust/ice mass ratio is probably larger than one, suggesting that comets are `icy dirtballs' rather than `dirty snowballs' as commonly believed. High dust velocities (between 110ms-1 and 300ms-1) imply acceleration in the comet's coma, probably by water molecules sublimated by solar radiation. We did not find evidence of enhanced activity of 9P/Tempel 1 in the days after the impact, suggesting that in general impacts of meteoroids are not the cause of cometary outbursts.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : Christophe CoudretG. GuiradoC. HortolaryJean-Pierre LaunayN. BattagliniH.R. KleinPhilippe Dumas
• Organismes : Centre Interdisciplinaire de Nanoscience de Marseille Centre Interdisciplinaire de Nanoscience de Marseille
• Publié dans Molecular Crystals and Liquid Crystals le 21/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2005
• Auteurs : Jean‐sébastien LauretChristophe VoisinSébastien BergerGuillaume CassaboisClaude DelalandePhilippe RoussignolLaurence Goux-CapesArianna Filoramo
• Organismes : Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire Pierre Aigrain Laboratoire d'Electronique Moléculaire Laboratoire d'Electronique Moléculaire
• Publié dans Physical Review B: Condensed Matter and Materials Physics (1998-2015) le 02/11/2020

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Résumé : Carrier dynamics is investigated in both luminescent and non luminescent samples of single wall carbon nanotubes -obtained by laser ablation- by means of two-color pump-probe experiments. The recombination dynamics is monitored by probing the transient photobleaching observed on the interband transitions of semi-conducting nanotubes. Interband and inter-subband relaxation times are about one order of magnitude slower in isolated nanotubes than in ropes of nanotubes bringing evidence of the environment influence on the carrier dynamics. The relaxation dynamics is non-exponential and is interpreted as a consequence of the inhomogeneity of the sample. Slow components up to 250 ps are measured which is significantly greater than values previoulsy reported in HiPCo nanotubes. These observations show the great dependence of the electronic properties of carbon nanotubes on the synthesis method and on their environment.

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Fichiers liés : voisin_prb.pdf

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