Philippe JEAN-PIERRE

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2004
• Auteurs : Jean-Philippe UzanNabila AghanimYannick Mellier
• Organismes : Institut d'Astrophysique de Paris Laboratoire de Physique Théorique d'Orsay [Orsay] Institut d'astrophysique spatiale Institut d'Astrophysique de Paris Laboratoire d'Etude du Rayonnement et de la Matière en Astrophysique
• Publié dans Physical Review D le 02/11/2020

---

Résumé : X-ray and Sunyaev-Zel\'dovich data of clusters of galaxies enable to construct a test of the distance duality relation between the angular and luminosity distances. We argue that such a test on large cluster samples may be of importance while trying to distinguish between various models of dark energy. The analysis of a data set of 18 clusters shows no significant violation of this relation. The origin and amplitude of systematic effects and the possibility to increase the precision of this method are discussed.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2004
• Auteurs : N. DuboulozAlain KerdraonPhilippe ZarkaJean-Michel Martin
• Organismes : Laboratoire d'études spatiales et d'instrumentation en astrophysique Physique des plasmas Laboratoire d'études spatiales et d'instrumentation en astrophysique Physique des plasmas
• Publié dans L'Astronomie le 26/02/2013

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2004
• Auteurs : Philippe KeckhutStuart McdermidDaan SwartThomas McgeeSophie Godin-BeekmannAlberto AdrianiJohn BarnesJean-Luc BarayHassan BencherifHans ClaudeAleide Di SarraGeorgio FioccoGeorg HansenAlain HauchecorneThierry LeblancChoo Hie LeeShiv PalGerard MegieHideaki NakaneRoland NeuberWolfgang SteinbrechtJeffrey Thayer
• Organismes : Service d'aéronomie National Institute for Public Health and the Environment [Bilthoven] NASA Goddard Space Flight Center Service d'aéronomie CNR Institute of Atmospheric Sciences and Climate National Oceanic and Atmospheric Administration Laboratoire de Météorologie Physique Observatoire de Physique du Globe de Clermont-Ferrand Laboratoire de physique de l'atmosphère Deutscher Wetterdienst [Offenbach] Norwegian Institute for Air Research Service d'aéronomie Jet Propulsion Laboratory Science and Art Innovation Inc. Service d'aéronomie National Institute for Environmental Studies Alfred-Wegener-Institut, Helmholtz-Zentrum für Polar- und Meeresforschung = Alfred Wegener Institute for Polar and Marine Research = Institut Alfred-Wegener pour la recherche polaire et marine Meteorologisches Observatorium Hohenpeißenberg University of Colorado [Boulder]
• Publié dans International Journal of Environmental Monitoring and Analysis le 06/02/2024

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2004
• Auteurs : Matthieu LengaigneÉric GuilyardiJean-Philippe BoulangerChristophe MenkesPascale DelécluseP. InnessJeff ColeJulia Slingo
• Organismes : Laboratoire d'océanographie dynamique et de climatologie Department of Meteorology [Reading] CGAM Laboratoire d'océanographie dynamique et de climatologie Laboratoire d'océanographie dynamique et de climatologie Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette] Department of Meteorology [Reading] CGAM Department of Meteorology [Reading] CGAM Department of Meteorology [Reading] CGAM
• Publié dans Climate Dynamics le 30/10/2020

---

Résumé : Two ten-members ensemble experiments using a coupled ocean-atmosphere general circulation model are performed to study the dynamical response to a strong westerly wind event (WWE) when the tropical Pacific has initial conditions favourable to the development of a warm event. In the reference ensemble (CREF), no wind perturbation is introduced, whereas a strong westerly wind event anomaly is introduced in boreal winter over the western Pacific in the perturbed ensemble (CWWE). Our results demonstrate that an intense WWE is capable of establishing the conditions under which a strong El Niño event can occur. First, it generates a strong downwelling Kelvin wave that generates a positive sea surface temperature (SST) anomaly in the central-eastern Pacific amplified through a coupled ocean-atmosphere interaction. This anomaly can be as large as 2.5°C 60 days after the WWE. Secondly, this WWE also initiates an eastward displacement of the warm-pool that promotes the occurrence of subsequent WWEs in the following months. These events reinforce the initial warming through the generation of additional Kelvin waves and generate intense surface jets at the eastern edge of the warm-pool that act to further shift warm waters eastward. The use of a ten-members ensemble however reveals substantial differences in the coupled response to a WWE. Whereas four members of CWWE ensemble develop into intense El Niño warming as described above, four others display a moderate warming and two remains in neutral conditions. This diversity between the members appears to be due to the internal atmospheric variability during and following the inserted WWE. In the four moderate warm cases, the warm-pool is initially shifted eastward following the inserted WWE, but the subsequent weak WWE activity (when compared to the strong warming cases) prevents to further shift the warm-pool eastwards. The seasonal strengthening of trade winds in June–July can therefore act to shift warm waters back into the western Pacific, reducing the central-eastern Pacific warming. This strong sensitivity of the coupled response to WWEs may therefore limit the predictability of El Niño events, as the high frequency wind variability over the warm pool region remains largely unpredictable even at short time lead.

---

Fichiers liés : Lengaigne2004.pdf

---

Source

---

• Type de publi. : Ouvrage (y compris édition critique et traduction)
• Date de publi. : 01/01/2004
• Auteurs : Philippe BourdeauJean CorneloupPascal Mao
• Organismes : Pacte, Laboratoire de sciences sociales Pacte, Laboratoire de sciences sociales Pacte, Laboratoire de sciences sociales

---

Source

---

• Type de publi. : Chapître d'ouvrage
• Date de publi. : 01/01/2004
• Auteurs : Philippe DessusJean-Yves Carpanèse
• Organismes : Laboratoire des Sciences de l'Éducation (Grenoble) French American School of Portland, USA Laboratoire des Sciences de l'Éducation (Grenoble)

---

Résumé : Cet article est l’occasion, d’une part, de commenter certains avis développés par Antoine Prost (2001) à propos de recherches contextualisées en éducation et, d’autre part, d’illustrer avec l’une des nôtres certains problèmes rencontrés en menant ce type de recherches. Plus particulièrement, nous nous centrerons sur les rapports délicats entre les sujets et le chercheur d’une recherche « contextualisée ». Nous montrerons que ces rapports sont liés à deux caractéristiques d’une recherche : ses validités interne et externe.

---

Fichiers liés : rechcontext04.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2004
• Auteurs : Alain RiazueloJeffrey WeeksJean-Philippe UzanRoland LehoucqJean-Pierre Luminet
• Organismes : Service de Physique Théorique Institut d'Astrophysique de Paris Astrophysique Interprétation Modélisation Laboratoire Univers et Théories Laboratoire Univers et Théories
• Publié dans Physical Review D le 02/11/2020

---

Résumé : This article investigates the signature of the seventeen multiconnected flat spaces in cosmic microwave background (CMB) maps. For each such space it recalls a fundamental domain and a set of generating matrices, and then goes on to find an orthonormal basis for the set of eigenmodes of the Laplace operator on that space. The basis eigenmodes are expressed as linear combinations of eigenmodes of the simply connected Euclidean space. A preceding work, which provides a general method for implementing multiconnected topologies in standard CMB codes, is then applied to simulate CMB maps and angular power spectra for each space. Unlike in the 3-torus, the results in most multiconnected flat spaces depend on the location of the observer. This effect is discussed in detail. In particular, it is shown that the correlated circles on a CMB map are generically not back to back, so that negative search of back-to-back circles in the Wilkinson Microwave Anisotropy Probe data does not exclude a vast majority of flat or nearly flat topologies.

---

Fichiers liés : PhysRevD.69.103518.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2004
• Auteurs : Armelle RoisinJean-Philippe RobinNathalie Dereuddre-BosquetAnne-Laure VitteDominique DormontPascal ClayettePierre Jalinot
• Organismes : Unité mixte de recherche biologie moléculaire de la cellule Unité mixte de recherche biologie moléculaire de la cellule Commissariat à l'énergie atomique et aux énergies alternatives Ministère des armées – Ministère de la défense [France] (1946-....) École Pratique des Hautes Études Université Paris-Sud - Paris 11 Unité mixte de recherche biologie moléculaire de la cellule Commissariat à l'énergie atomique et aux énergies alternatives Ministère des armées – Ministère de la défense [France] (1946-....) École Pratique des Hautes Études Université Paris-Sud - Paris 11 Commissariat à l'énergie atomique et aux énergies alternatives Ministère des armées – Ministère de la défense [France] (1946-....) École Pratique des Hautes Études Université Paris-Sud - Paris 11 Unité mixte de recherche biologie moléculaire de la cellule
• Publié dans Journal of Biological Chemistry le 02/11/2020

---

Résumé : New therapeutic agents able to block HIV-1 replication are eagerly sought after to increase the possibilities of treatment of resistant viral strains. In this report, we describe a rational strategy to identify small peptide sequences owning the dual property of penetrating within lymphocytes and of binding to a protein target. Such sequences were identified for two important HIV-1 regulatory proteins, Tat and Rev. Their association to a stabilizing domain consisting of human small ubiquitin-related modifier-1 (SUMO-1) allowed the generation of small proteins named SUMO-1 heptapeptide protein transduction domain for binding Tat (SHPT) and SUMO-1 heptapeptide protein transduction domain for binding Rev (SHPR), which are stable and efficiently penetrate within primary lymphocytes. Analysis of the antiviral activity of these proteins showed that one SHPR is active in both primary lymphocytes and macrophages, whereas one SHPT is active only in the latter cells. These proteins may represent prototypes of new therapeutic agents targeting the crucial functions exerted by both viral regulatory factors.

---

Fichiers liés : 77161_20101105041843873_1.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2004
• Auteurs : Pascal DranéEmmanuel CompePhilippe CatezPierre ChymkowitchJean-Marc Egly
• Organismes : Institut de génétique et biologie moléculaire et cellulaire Institut de génétique et biologie moléculaire et cellulaire Institut de génétique et biologie moléculaire et cellulaire Institut de génétique et biologie moléculaire et cellulaire Institut de génétique et biologie moléculaire et cellulaire
• Publié dans Molecular Cell le 29/10/2020

---

Résumé : Mutations in the XPD subunit of the transcription/repair factor TFIIH cause the Xeroderma pigmentosum disorder. We show that in some XP-D deficient cells, transactivation by the vitamin D receptor (VDR) is selectively inhibited for a subset of responsive genes, such as CYP24, and that the XPD/R683W mutation prevents VDR recruitment on its promoter. Contrary to other nuclear receptors, VDR, which lacks a functional A/B domain, is not phosphorylated and consequently not regulated by the cdk7 kinase of TFIIH. In fact, we demonstrate that the VDR transactivation defect resides in Ets1, another activator that cannot be phosphorylated by TFIIH in XP-D cells. Indeed, the phosphorylated Ets1 seems to promote the binding of VDR to its responsive element and trigger the subsequent recruitment of coactivators and RNA pol II. We propose a model in which TFIIH regulates the activity of nuclear receptors by phosphorylating either their A/B domain or an additional regulatory DNA binding partner.

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2004
• Auteurs : R. BoucheronJ.C. ValierePhilippe HerzogHélène BaillietJean-Pierre Dalmont
• Organismes : Laboratoire de Mécanique et d'Acoustique [Marseille] Laboratoire d'Acoustique de l'Université du Mans

---

Source