Philippe JEAN-PIERRE

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2003
• Auteurs : Sébastien Le JanCéline AmyAurélie CazesCatherine MonnotNoël LamandéJudith FavierJosette PhilippeMathilde SibonyJean-Marie GascPierre CorvolStéphane Germain
• Organismes : Angiogénèse embryonnaire et pathologique Pathologie vasculaire et endocrinologie rénale - Chaire de médecine expérimentale Centre interdisciplinaire de recherche en biologie
• Publié dans American Journal of Pathology le 26/10/2020

---

Résumé : Ischemic and solid tumor tissues are less well perfused than normal tissue, leading to metabolic changes and chronic hypoxia, which in turn promotes angiogenesis. We identified human angiopoietin-like 4 (angptl4) as a gene with hypoxia-induced expression in endothelial cells. We showed that the levels of both mRNA and protein for ANGPTL4 increased in response to hypoxia. When tested in the chicken chorioallantoic membrane assay, ANGPTL4 induced a strong proangiogenic response, independently of vascular endothelial growth factor. In human pathology, ANGPTL4 mRNA is produced in ischemic tissues, in conditions such as critical leg ischemia. In tumors, ANGPTL4 is produced in the hypoxic areas surrounding necrotic regions. We observed particularly high levels of ANGPTL4 mRNA in tumor cells of conventional renal cell carcinoma. Other benign and malignant renal tumor cells do not produce ANGPTL4 mRNA. This molecule therefore seems to be a marker of conventional renal cell carcinoma. ANGPTL4, originally identified as a peroxisome proliferator-activated receptor alpha and gamma target gene, has potential for use as a new diagnostic tool and a potential therapeutic target, modulating angiogenesis both in tumors and in ischemic tissues. This study also suggests that ANGPTL4 may provide a link between metabolic disorders and hypoxia-induced angiogenesis.

---

Source

---

• Type de publi. : Chapître d'ouvrage
• Date de publi. : 01/01/2003
• Auteurs : Jean CorneloupPhilippe BourdeauPascal MaoEric Boutroy
• Organismes : Pacte, Laboratoire de sciences sociales Pacte, Laboratoire de sciences sociales Pacte, Laboratoire de sciences sociales

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2003
• Auteurs : Cedric DumoulinPierre BouletJean-Luc DekeyserPhilippe Marquet
• Organismes : Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time Laboratoire d'Informatique Fondamentale de Lille Contributions of the Data parallelism to real time

---

Résumé : The development of embedded applications is very difficult. Several different languages are usually used to specify different parts of the application or of the hardware. Dealing with so many languages can be daunting. A separation of the preoccupations: application, hardware architecture, association between them and the simulation or execution technologies are keys to efficient co-design of embedded applications. The Model Driven Architecture can be used to better deal with the reuse of parts of the design and the interoperability between both the implementation technologies and the various simulation levels. par We propose a construction of metamodels to support a co-design methodology. This construction will be experimented on intensive signal processing application co-design to justify the adequacy of this methodology to usual industrial development techniques.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2003
• Auteurs : Gilles DusserreSophie SauvagnarguesAurélia Bony-DandrieuxJérôme TixierSébastien Rault DoumaxPierre-Alain AyralJean-Philippe DimbourKarin HaldDaas Jabbour
• Organismes : Laboratoire de Génie de l'Environnement Industriel Laboratoire de Génie de l'Environnement Industriel Laboratoire de Génie de l'Environnement Industriel Laboratoire de Génie de l'Environnement Industriel Laboratoire de Génie de l'Environnement Industriel
• Publié dans Réalités industrielles. Annales des mines le 29/10/2020

---

Fichiers liés : Contribution_a_laide_a_la_decision_en_situation_d.pdf

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 01/01/2003
• Auteurs : Jean MartinetYves ChiaramellaPhilippe MulhemIadh Ounis
• Organismes : FOX MIIRE Communication Langagière et Interaction Personne-Système Modélisation et Recherche d’Information Multimédia [Grenoble] School of Computing Science [Glasgow]

---

Résumé : We present in this paper a relational approach for indexing and retrieving photographs from a collection. Instead of using simple keywords as an indexing language, we propose to use star-graphs as document descriptors. A star-graph is a conceptual graph that contains a single relation, with some concepts linked to it. They are elementary pieces of information describing combinations of concepts. We use star-graphs as descriptors - or index terms - for image content representation. This allows for relational indexing and expression of complex user needs, in comparison to classical text retrieval, where simple keywords are generally used as document descriptors. We present a document representation model, a weighting scheme for star-graphs inspired by the tf.idf used in text retrieval. We have applied our model to image retrieval, and show the system evaluation results.

---

Fichiers liés : cbmi03-submitted.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2003
• Auteurs : Guillaume MorinFarid JuillotCorinne CasiotOdile BruneelJean-Christian PersonnéFrançoise Elbaz-PoulichetMarc LeblancPhilippe IldefonseGeorges Calas
• Organismes : Institut de minéralogie et de physique des milieux condensés Institut de minéralogie et de physique des milieux condensés Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Institut de minéralogie et de physique des milieux condensés Institut de minéralogie et de physique des milieux condensés
• Publié dans Environmental Science and Technology le 24/10/2020

---

Résumé : The oxidation of Fe(II) in acid mine drainage (AMD) leads to the precipitation of Fe(III) compounds which may incorporate toxic elements, such as arsenic (As), within their structure or adsorb them at their surface, thus limiting their mobility. The present work provides evidence for spatial and seasonal variations of microbial activity that influence arsenite oxidation and As immobilization in the heavily contaminated AMD from the Carnoulès mine, Gard, France ([As III] = 80 to 280 mg·L-1 in the acidic spring draining the waste-pile). In the first tens of meters of the AMD, the rapid oxidation of Fe(II) leads to the coprecipitation of large amounts of As with Fe(III) in bacterial mats. XRD, XANES, and SEM analyses of sediments and stromatolite samples revealed the unusual formation of As(III)-rich compounds, especially nanocrystalline tooeleite, Fe6(AsO3)4(SO4)(OH)4·4H2O, a rare ferric arsenite sulfate oxy-hydroxide mineral, together with XRD-amorphous mixed As(III)/As(V)-Fe(III) oxy-hydroxide compounds. In the wet season, the suspended sediments of the upstream zone essentially consist of tooeleite associated with am-As(III)-Fe(III) oxy-hydroxides, while am-As(V)-Fe(III) oxy-hydroxides, having As:Fe molar ratios as high as 0.6-0.8, dominate in the dry season. Comparing natural and bioassay samples revealed that the formation of As(III)-rich compounds in the wet season may be related to the metabolic activity of bacterial strains able to oxidize Fe(II) but not As(III). One of these strains, having an Acidithiobacillus ferrooxidans genotype, has been isolated from the Carnoulès AMD. In contrast, the formation of As(V)-rich compounds in the dry season can be related to both biotic and abiotic oxidation of As(III) to As(V). Some Thiomonas strains isolated from the Carnoulès AMD were shown to be able to catalyze the oxidation of As(III) to As(V) in solution. Therefore, they can promote the formation of mixed As(V)-Fe(III) oxy-hydroxides, provided enough Fe(II) oxidizes. These results yield a better understanding of natural processes at this site and may help in designing efficient As-removal processes.

---

Fichiers liés : Morin et al 2003.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2003
• Auteurs : Tantely RandriambeloJean-Luc BaraySerge BaldyA. M. ThompsonS. OltmansPhilippe Keckhut
• Organismes : Laboratoire de l'Atmosphère et des Cyclones Laboratoire de l'Atmosphère et des Cyclones Laboratoire de l'Atmosphère et des Cyclones NASA Goddard Laboratory for Atmosphere NOAA Climate Monitoring and Diagnostics Laboratory Service d'aéronomie
• Publié dans Annales Geophysicae le 26/10/2020

---

Résumé : Since 1998, a ground-based tropospheric ozone lidar has been running at Reunion Island and has been involved with a daily measurement campaign that was performed in the latter part of the biomass burning season, during November–December 1999. The averaged ozone profile obtained during November–December 1999 agrees well with the averaged ozone profile obtained from the ozonesondes launch at Reunion during November–December (1992– 2001). Comparing weekly sonde launches (part of the Southern Hemisphere Additional Ozonesondes: SHADOZ program) with the daily ground-based lidar observations shows that some striking features of the day-to-day variability profiles are not observed in the sonde measurements. Ozone profiles respond to the nature of disturbances which vary from one day to the next. The vertical ozone distribution at Reunion is examined as a function of prevailing atmospheric circulation. Back trajectories show that most of the enhanced ozone crossed over biomass burning and convectively active regions in Madagascar and the southern African continent. The analyses of the meteorological data show that ozone stratification profiles are in agreement with the movement of the synoptic situations in November–December 1999. Three different sequences of transport are explained using wind fields. The first sequence from 23 to 25 November is characterized by northerly transport; during the second sequence from 26 to 30 November, the air masses are influenced by meridional transport. The third sequence from 2 to 6 December is characterized by westerly transport associated with the sub-tropical jet stream. The large, standard deviations of lidar profiles in the middle and upper troposphere are in agreement with the upper wind variabilities which evidence passing ridge and trough disturbances. During the transition period between the dry season and the wet season, multiple ozone sources including stratosphere-troposphere exchanges, convection and biomass burning contribute to tropospheric ozone at Reunion Island through sporadic events characterized by a large spatial and temporal variability.

---

Fichiers liés : angeo-21-2095-2003.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2003
• Auteurs : Philippe BorgardJean-Pierre BrunLeguilloux MartineMarie Tuffreau-Libre
• Organismes : Centre Camille Jullian - Histoire et archéologie de la Méditerranée et de l'Afrique du Nord de la protohistoire à la fin de l'Antiquité Centre Jean Berard Centre Archéologique du Var Civilisations atlantiques & Archéosciences
• Publié dans Rivista di Studi Pompeiani le 22/01/2018

---

Source

---

• Type de publi. : Rapport
• Date de publi. : 01/01/2003
• Auteurs : Philippe de ReffyeMaurice GoursatJean-Pierre QuadratBaogang Hu
• Organismes : Methods, algorithms and software in automatic control Methods, algorithms and software in automatic control Methods, algorithms and software in automatic control Eco-informatics

---

Résumé : We explicit the dynamic equations followed by a tree during its growth according to the Greenlab model. In a first part we explicit the Organogenesis equations. In the second part, we recall the equations which, using a macroscopic photosynthesis point of view, describe with a great precision the evolution of the organ sizes. In a third part we establish the morphogenesis equations describing the geometry of a tree. The three parts are illustrated with an example.

---

Fichiers liés : RR-4877.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2003
• Auteurs : Nicolas MercierNicolas MercierPierre FrèrePhilippe BlanchardJean RoncaliMagali AllainChristophe PasquierAmédée Riou
• Organismes : Laboratoire de Physique des Solides - HP
• Publié dans Inorganic Chemistry le 31/10/2020

---

Résumé : 2,2′-bithiophene derivatives, 5-ammoniumethylsulfanyl-2,2′-bithiophene (AESBT) and 5,5′-bis(ammoniumethylsulfanyl)-2,2′-bithiophene (BAESBT), have been designed for their incorporation in organic-inorganic materials based on iodometalates. Three layered compounds, (BAESBT)Pbl4, (AESBT) 4Pb3l10, and (AESBT)3Bl 2l9, have been synthesized as crystals from slowly cooled aqueous solution containing metal halide and bithiophene derivative salts. When starting from the diammonium cation, (BAESBT)Pbl4 hybrid perovskite is obtained. (BAESBT)Pbl4 adopts a triclinic cell (P1̄) with the lattice parameters a = 8.4741(5) Å, b = 8.9255(6) Å, c = 16.876(1) Å, α = 88.328(5)°, β = 81.806(4)°, γ = 88.864(5)°, Z = 2. In the structure, Pbl42- perovskite sheets and diammonium cation layers alternate along c. The incorporation of the corresponding monoammonium cation (AESBT) leads to a head to tail arrangement of the molecules in the (AESBT)4Pb 3l10 hybrid, precluding the formation of the perovskite layers. (AESBT)4Pb3l10 is orthorhombic, Pna21, with a = 38.333(4) Å, b = 22.239(3) Å, c = 8.448(2) Å, Z = 4. The structure consists of corrugated layers of Pb 3l104- separated by organic layers of monoammonium cations. A similar relative situation of molecules in organic layers is observed in (AESBT)3Bi2l9, with the inorganic sheets being built up from Bi2l93- entities. (AESBT)3Bi2l9 crystallizes in an orthorhombic cell (P212121) with a = 8.4564(6) Å, b = 21.368(2) Å, c = 30.747(2) Å, Z = 4. In the three compounds, the molecular packings appear different, underlining the interplay between both organic and inorganic components. New packings are stabilized, as illustrated by an original mixed kappa-alpha type arrangement of the bithiophene units in (AESBT)3Bi2l9. Furthermore, molecular interactions, especially of S...S type, appear stronger in the hybrids based on the monoammonium cations. The electrical conductivity of a (BAESBT)Pbl4 single crystal has also been investigated, revealing a semiconductive behavior with a characteristic energy of E g = 2.535 eV.

---

Source