Philippe JEAN-PIERRE

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• Type de publi. : Ouvrage (y compris édition critique et traduction)
• Date de publi. : 01/01/1986
• Auteurs : Annie BrownLionel DumarchePhilippe GlorennecJean-Marcel HumbertE. SoullardP. HervetJean-Pierre Verney
• Organismes : Musée de l'Armée, Paris Musée de l'Armée, Paris

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Résumé : Catalogue de l’exposition organisée à la gare de l'Est en 1986, consacrée à la Première Guerre mondiale et à la mémoire combattante. L’ouvrage met l’accent sur l'expérience du front, les objets du quotidien des soldats et les représentations de la guerre dans l’imaginaire collectif.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/1986
• Auteurs : Jean-Loup BertauxBernard MegeAlain AbergelAlain HauchecorneJean-Pierre PommereauPhilippe RigaudAlexei P. EkonomovV. I. MorozV. I. GnedykhA.V. Grigor'EvBoris E. MoshkinS. B. Sergeeva
• Organismes : Service d'aéronomie Service d'aéronomie Service d'aéronomie Service d'aéronomie Service d'aéronomie Service d'aéronomie Space Research Institute of the Russian Academy of Sciences Space Research Institute of the Russian Academy of Sciences Space Research Institute of the Russian Academy of Sciences Space Research Institute of the Russian Academy of Sciences Space Research Institute of the Russian Academy of Sciences Space Research Institute of the Russian Academy of Sciences
• Publié dans Soviet astronomy letters le 21/01/2021

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Fichiers liés : 1986SvAL___12___33B.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 05/08/1985
• Auteurs : Pascale RombyDino MorasMarc BergdollPhilippe DumasValentin V. VlassovÉric WesthofJean Pierre EbelRichard Giegé
• Organismes :
• Publié dans Journal of Molecular Biology le 28/10/2020

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Résumé : Ethylnitrosourea is an alkylating reagent preferentially modifying phosphate groups in nucleic acids. It was used to monitor the tertiary structure, in solution, of yeast tRNAAsp and to determine those phosphate groups in contact with the cognate aspartyl-tRNA synthetase. Experiments involve 3′ or 5′-end-labelled tRNA molecules, low yield modification of the free or complexed nucleic acid and specific splitting at the modified phosphate groups. The resulting end-labelled oligonucleotides are resolved on polyacrylamide sequencing gels and data analysed by autoradiography and densitometry. Experiments were conducted in parallel on yeast tRNAAsp and on tRNAPhe. In that way it was possible to compare the solution structure of two elongator tRNAs and to interpret the modification data using the known crystal structures of both tRNAs. Mapping of the phosphates in free tRNAAsp and tRNAPhe allowed the detection of differential reactivities for phosphates 8, 18, 19, 20, 22, 23, 24 and 49: phosphates 18, 19, 23, 24 and 49 are more reactive in tRNAAsp, while phosphates 8, 20 and 22 are more reactive in tRNAPhe. All other phosphates display similar reactivities in both tRNAs, in particular phosphate 60 in the T-loop, which is strongly protected. Most of these data are explained by the crystal structures of the tRNAs. Thermal transitions in tRNAAsp could be followed by chemical modifications of phosphates. Results indicate that the D-arm is more flexible than the T-loop. The phosphates in yeast tRNAAsp in contact with aspartyl-tRNA synthetase are essentially contained in three continuous stretches, including those at the corner of the amino acid accepting and D-arm, at the 5′ side of the acceptor stem and in the variable loop. When represented in the three-dimensional structure of the tRNAAsp, it clearly appears that one side of the L-shaped tRNA molecule, that comprising the variable loop, is in contact with aspartyl-tRNA synthetase. In yeast tRNAPhe interacting with phenylalanyl-tRNA synthetase, the distribution of protected phosphates is different, although phosphates in the anticodon stem and variable loop are involved in both systems. With tRNAPhe, the data cannot be accommodated by the interaction model found for tRNAAsp, but they are consistent with the diagonal side model proposed by Rich & Schimmel (1977). The existence of different interaction schemes between tRNAs and aminoacyl-tRNA synthetases, correlated with the oligomeric structure of the enzyme, is proposed.

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• Type de publi. : Article dans une revue
• Date de publi. : 25/07/1985
• Auteurs : Frederique KuttennPhilippe CouillinFrançois GirardLine BillaudMonique VincensChafika BoucekkineJean-Christophe ThalabardThierry MaudelondePoli SpritzerIrene MowszowiczAndre BouePierre Mauvais-Jarvis
• Organismes : Hôpital Necker - Enfants Malades [AP-HP] Unité 73 CHU Trousseau [APHP] Hôpital Necker - Enfants Malades [AP-HP] CHU Pitié-Salpêtrière [AP-HP] Mathématiques Appliquées Paris 5 Hôpital Necker - Enfants Malades [AP-HP] Gynecological Endocrinology Unit, Division of Endocrinology, Hospital de Clinicas de Porto Alegre CHU Pitié-Salpêtrière [AP-HP] Hôpital Necker - Enfants Malades [AP-HP]
• Publié dans New England Journal of Medicine le 29/10/2020

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Résumé : We studied the incidence of late-onset adrenal hyperplasia as a cause of hirsutism, its association with the major histocompatibility complex, and its clinical expression. Twenty-four of 400 women seen because of hirsutism were found to have late-onset adrenal hyperplasia, diagnosed on the basis of a high plasma level of 17-hydroxyprogesterone, and its marked increase after ACTH stimulation. The degree of hirsutism varied widely. Plasma antigen levels were high, especially the level of androstenedione, whereas 5 alpha-reductase activity, considered to be a good index of peripheral androgen utilization, showed frequent normal or low values. The 24 patients were genotyped, along with 84 family members, and plasma hormones were measured in the family members. We found a high correlation between late-onset adrenal hyperplasia and HLA antigens B14 and Aw33. Similar biologic profiles were observed in the patients and those of their siblings who were HLA identical (n = 9), confirming that late-onset adrenal hyperplasia is linked to the histocompatibility complex. These nine siblings had no hirsutism. We therefore conclude that the role of skin sensitivity to androgens is important in determining the clinical expression of this disorder.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/1985
• Auteurs : Annie Gautier-HionJean-Marc DuplantierRené QurisF. FeerC. SourdJ. -P. DecouxGerard DubostLouise H. EmmonsC. ErardPhilippe HecketsweilerAugustin MoungaziC. RoussilhonJ. -M. Thiollay
• Organismes : Fonctionnement, évolution et mécanismes régulateurs des écosystèmes forestiers URA373 Laboratoire d'Ethologie [Ontogenèse et valeur adaptative des comportements] Centre de Biologie pour la Gestion des Populations URA373 Laboratoire d'Ethologie [Ontogenèse et valeur adaptative des comportements] Mécanismes adaptatifs : des organismes aux communautés Muséum national d'Histoire naturelle Department of Invertebrate Zoology Institut de Recherche en Ecologie Tropicale Fonctionnement, évolution et mécanismes régulateurs des écosystèmes forestiers Institut de Recherche en Ecologie Tropicale Fonctionnement, évolution et mécanismes régulateurs des écosystèmes forestiers Institut de Recherche en Ecologie Tropicale
• Publié dans Oecologia le 30/10/2020

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Résumé : Interactions between a large community of vertebrate frugivore-granivores (including 7 species of large canopy birds, 19 species of rodents, 7 species of ruminants, and 6 species of monkeys), and 122 fruit species they consume, were studied for a year in a tropical rainforest in Gabon. The results show how morphological characters of fruits are involved in the choice and partitioning of the available fruit spectrum among consumer taxa. Despite an outstanding lack of specificity between fruit and consumer species, consideration of simple morphological traits of fruits reveals broad character syndromes associated with different consumer taxa. Competition between distantly related taxa that feed at the same height is far more important than has been previously supposed. The results also suggest how fruit characters could have evolved under consumer pressure as a result of consumer roles as dispersers or seed predators. Our analyses of dispersal syndromes show that fruit species partitioning occurs more between mammal taxa than between mammals and birds. There is thus a bird-monkey syndrome and a ruminant-rodent-elephant syndrome. The bird-monkey syndrome includes fruit species on which there is no pre-dispersal seed predation. These fruits (berries and drupes) are brightly colored, have a succulent pulp or arillate seeds, and no protective seed cover. The ruminant-rodent-elephant syndrome includes species for which there is pre-dispersal predation. These fruits (all drupes) are large, dull-colored, and have a dry fibrous flesh and well-protected seeds.

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• Type de publi. : Rapport
• Date de publi. : 01/01/1985
• Auteurs : Evelyne ServerinPhilippe ClémentChristiane BeroujonSylvie BruxellesOdile DomenachAntoine JeammaudFrançoise Vennin
• Organismes : Centre de Recherches Critiques sur le Droit Centre Pierre Léon d'Histoire Économique et Sociale Informatique, Droit, Linguistique Centre de Recherches Critiques sur le Droit Centre de Recherches Critiques sur le Droit Centre de Recherches Critiques sur le Droit

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Résumé : Décrit et analyse certaines formes juridiques et pratiques sociales relatives au traitement non juridictionnel des conflits.

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Fichiers liés : conciliation_Version2_optimisé.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/1985
• Auteurs : Philippe ColombanJean-Pierre Boilot
• Organismes : De la Molécule aux Nanos-objets : Réactivité, Interactions et Spectroscopies Laboratoire de physique de la matière condensée
• Publié dans Revue de Chimie Minerale le 01/01/2003

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Fichiers liés : Rev Chim Mine Sol-Gel 1985 T22(2).pdf

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• Type de publi. :
• Date de publi. : 18/09/1984
• Auteurs : Jean-Yves MoisanPhilippe GraveyJean-Pierre FouassierDaniel Joseph Lougnot
• Organismes : CNET CNET Département de Photochimie Générale Département de Photochimie Générale

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• Type de publi. : Communication dans un congrès
• Date de publi. : 02/05/1983
• Auteurs : Richard GiegéPascale RombyCatherine FlorentzJean-Pierre EbelPhilippe DumasÉric WesthofDino Moras
• Organismes : Institut de biologie moléculaire et cellulaire Institut de biologie moléculaire et cellulaire Institut de biologie moléculaire et cellulaire Institut de biologie moléculaire et cellulaire Institut de biologie moléculaire et cellulaire Institut de biologie moléculaire et cellulaire Institut de biologie moléculaire et cellulaire

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• Type de publi. : Rapport
• Date de publi. : 01/01/1983
• Auteurs : Philippe BoudonPhilippe DeshayesEtienne FalkHervé GrailleJean-Pierre PerrinFrançoise Schatz
• Organismes : Laboratoire d'architecturologie et de recherches épistémologiques sur l'architecture

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Fichiers liés : MC_BRAUP_0192_83_TXT1_001_BD.pdf

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