Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 16/11/2023
• Auteurs : Quynh Bach Thi NhuLinh Le Thi ThuyHong Thi NguyenBinh Nguyen ThanhDelphine RapoudCatherine QuilletHong Thi TranR. ValloThanh Nham Thi TuyetLaurent MichelLaurence WeissPhilippe Vande PerreVinh Vu HaiNicolas NagotOanh Khuat Thi HaiDon Des JarlaisHuong Duong ThiPham Minh KhueDidier LaureillardJean-Pierre Moles
• Organismes : Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Immunologie humaine, physiopathologie & immunothérapie Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections
• Publié dans Diagnostics le 01/11/2020

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Résumé : The desired performance of nucleic acid testing (NAT) may vary if used for disease diagnosis or for the evaluation of the therapeutic efficacy of a treatment, although in most cases, the same assay is used. However, these tests may not be affordable in many situations including in low/middle income countries that in response have developed domestic assays. Given the example of HCV NAT among people who inject drugs in Vietnam, we aimed at evaluating a domestic assay versus an FDA-and CE-approved assay. This cross-evaluation revealed that (i) the domestic assay had a poorer sensitivity with a threshold of detection above 10 4 IU/mL, and (ii) the FDA-approved assay had a percentage of false negative results close to 1%. Together, in the present study, the domestic assay had a performance compatible with diagnosis purposes (given that this population was 70% HCV seropositive) but not compatible with HCV treatment monitoring (given that treatment failures are rare and the observed viremia frequently below the threshold of detection). This study highlights the need for a proper evaluation of HCV RNA domestic assays in order to efficiently contribute to the WHO HCV elimination target by 2030.

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Fichiers liés : diagnostics-13-03456.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 16/11/2023
• Auteurs : Elise LaruelleJean-Christophe PalauquiPhilippe AndreyAlain Trubuil
• Organismes : Institut Jean-Pierre Bourgin - Sciences du végétal Mathématiques et Informatique Appliquées du Génome à l'Environnement [Jouy-En-Josas] Sainsbury Laboratory Cambridge University Institut Jean-Pierre Bourgin - Sciences du végétal Institut Jean-Pierre Bourgin - Sciences du végétal Mathématiques et Informatique Appliquées du Génome à l'Environnement [Jouy-En-Josas]
• Publié dans Plant Methods le 27/10/2020

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Résumé : Background With the emergence of deep-learning methods, tools are needed to capture and standardize image annotations made by experimentalists. In developmental biology, cell lineages are generally reconstructed from timelapse data. However, some tissues need to be fixed to be accessible or to improve the staining. In this case, classical software do not offer the possibility of generating any lineage. Because of their rigid cell walls, plants present the advantage of keeping traces of the cell division history over successive generations in the cell patterns. To record this information despite having only a static image, dedicated tools are required. Results We developed an interface to assist users in the building and editing of a lineage tree from a 3D labeled image. Each cell within the tree can be tagged. From the created tree, cells of a sub-tree or cells sharing the same tag can be extracted. The tree can be exported in a format compatible with dedicated software for advanced graph visualization and manipulation.

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Fichiers liés : laruelle2023-TreeJ.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 15/11/2023
• Auteurs : Philippe Saint-PierreNicolas Savy
• Organismes : Institut de Mathématiques de Toulouse UMR5219 Institut de Mathématiques de Toulouse UMR5219
• Publié dans The international journal of biostatistics le 27/10/2020

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Résumé : Abstract Simulation studies are promising in medical research in particular to improve drug development. For instance, one can aim to develop In Silico Clinical Trial in order to challenge trial’s design parameters in terms of feasibility and probability of success of the trial. Approaches based on agent-based models draw on a particularly useful framework to simulate patients evolution. In this paper, an approach based on agent-based modeling is described and discussed in the context of medical research. An R-vine copula model is used to represent the multivariate distribution of the data. A baseline data cohort can then be simulated and execution models can be developed to simulate the evolution of patients. R-vine copula models are very flexible tools which allow researchers to consider different marginal distributions than the ones observed in the data. It is then possible to perform data augmentation to explore a new population by simulating baseline data which are slightly different than those of the original population. A simulation study illustrates the efficiency of copula modeling to generate data according to specific marginal distributions but also highlights difficulties inherent to data augmentation.

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• Type de publi. : Article dans une revue
• Date de publi. : 15/11/2023
• Auteurs : Romain DemeulemeesterNicolas SavyPascale GrosclaudeNadège CostaPhilippe Saint-Pierre
• Organismes : Centre Hospitalier Universitaire de Toulouse Institut de Mathématiques de Toulouse UMR5219 Oncopole Claudius Regaud Institut Universitaire du Cancer de Toulouse - Oncopole Equipe EQUITY (CERPOP) Centre d'Epidémiologie et de Recherche en santé des POPulations Institut de Mathématiques de Toulouse UMR5219 Institut Universitaire de Technologie - Paul Sabatier
• Publié dans The international journal of biostatistics le 27/10/2020

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Résumé : Although they remain little used in the field of Health Care Economics, Agent Based Models (ABM) are potentially powerful decision-making tools that open up great prospects. The reasons for this lack of popularity are essentially to be found in a methodology that should be further clarified. This article hence aims to illustrate the methodology by means of two applications to medical examples. The first example of ABM illustrates the construction of a Baseline Data Cohort by means of a Virtual Baseline Generator. The aim is to describe the prevalence of thyroid cancer in the French population over the long term according to different scenarios of evolution of this population. The second study considers a setting where the Baseline Data Cohort is an established cohort of (real) patients: the EVATHYR cohort. The aim of the ABM is to describe the long-term costs associated with different scenarios of thyroid cancer management. The results are evaluated using several simulation runs in order to observe the variability of simulations and to derive prediction intervals. The ABM approach is very flexible since several sources of data can be involved and a large variety of simulation models can be calibrated to generate observations according to different evolution scenarios.

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• Type de publi. : Article dans une revue
• Date de publi. : 14/11/2023
• Auteurs : Philipp KlossMaximilian LindholzAnnette MilnikÉlie AzoulayMaurizio CecconiGiuseppe CiterioThomas de CorteFrantisek DuskaLaura GalarzaMassimiliano GrecoArmand GirbesJozef KeseciogluJohannes MellinghoffMarlies OstermannMariangela PellegriniJean-Louis TeboulJan de WaeleAdrian WongStefan SchallerBuenos AiresAlicia GiraPhilipp EllerTarikul HamidInjamam Ull HaqueWim de BuyserAntonella CudiaDaniel de BackerPierre FoulonVincent CollinJolien van HeckeElisabeth de WaeleClaire van MalderenJean-Baptiste MeslandPatrick BistonMichael PiagnerelliLionel HaentjensNicolas de SchryverJan van LeemputPhilippe VanhovePierre BulpaViktoria IlievaDavid KatzAlexandra BinnieAnna GeageaFernando TirapeguiGustavo LagoJerónimo GrafRodrigo Perez-AraosPatricio VargasFelipe MartinezEduardo LabarcaDaniel Molano FrancoDaniela Parra-TanouxDavid YepesAhmed HammoudaOmar ElmandouhAhmed AzzamAliae Mohamed HusseinIslam GalalAhmed AwadMohammed AzabMaged AbdallaHebatallah AssalMostafa AlfishawySherief GhozySamar TharwatAbdullah EldalyAnneli EllerveeVeronika ReinhardAnne ChrismentChrystelle PoyatJulio BadieFernando Berdaguer FerrariBjörn WeissClara SchellenbergJulius GrunowMarco LorenzStefan SchallerPeter SpiethMarc BotaFalk FichtnerKristina FuestTobias LahmerJohannes HerrmannPatrick MeybohmNikolaos MarkouGeorgia VasileiadouEvangelia ChrysanthopoulouPanagiotis PapamichalisIoanna SoultatiSameer JogKushal KalvitSheila Nainan MyatraIvan KrupaAisa TharwatAlistair NicholAine MccarthyAta MahmoodpoorTommaso TonettiPaolo IsoniSavino SpadaroCarlo Alberto VoltaLucia MirabellaAlberto NotoGaetano FlorioAmedeo GuzzardellaChiara PaleariFederica BaccanelliMarzia SaviMassimo AntonelliGennaro de PascaleBarbara VaccariniGiorgia MontrucchioGabriele SalesKatia DonadelloLeonardo GottinMarta NizzeroEnrico PolatiSilvia de RosaDemet SulemanjiAbdurraouf AbusalamaMuhammed ElhadiMontelongo Felipe De JesusDaniel Rodriguez GonzalezVictor Hugo Madrigal RoblesNancy CanedoAlejandro Esquivel ChavezTarek DendaneBart GradyBen de JongEveline van der HeidenPatrick ThoralBas van den BogaardPeter SpronkSefanja AchterbergMelanie GroeneveldRalph SoCalvin de WijsHarm ScholtenAlbertus BeishuizenAlexander CornetAuke ReidingaHetty KranenRoos MensinkSylvia den BoerMarcel de GrootOliver BeckCarina BethlehemBas van BusselTim FrenzelCelestine de JongRob WiltingJannet Mehagnoul-SchipperDatonye AlasiaAshok KumarAhad QayyumMuhammad RanaMustafa Abu JayyabRosario Quispe SierraAaron Mark HernandezLúcia TabordaMónica AnselmoTiago RamiresCatarina SilvaCarolina RorizRui MoraisPedro PóvoaPatricia PatricioAndré PintoMaria Lurdes SantosVasco CostaPedro CunhaCelina GonçalvesSandra NunesJoão CamõesDiana AdriãoAna OliveiraAli OmraniMuna Al MaslamaniAbdurrahmaan Suei ElbuzidiBara Mahmoud Al QudahAbdel Rauof AkkariMohamed AlkhattebAnas BaiouAhmed HusainMohamed AlwraidatIbrahim Abdulsalam SaifDana BakdachAmna AhmedMohamed AleefAwadh BintaherCristina PetrisorEvgeniy PopovKsenia PopovaMariia DementienkoBoris TeplykhAlexey PyregovLiubov DavydovaBelskii VladislavElena NeporadaIvan ZverevSvetlana MeshchaninovaDmitry SokolovElena GavrilovaIrina ShlykIgor PoliakovMarina VlasovaOhoud AljuhaniAmina AlkhalafFelwa Bin HumaidYaseen ArabiAhmed KuhailOmar ElrabiMadihah GhannamAmit KansalVui Kian HoJensen NgRaquel Rodrígez GarcíaXiana Taboada FragaMª del Pilar García-BonilloAntonio Padilla-SerranoMarta Martin CuadradoCarlos FerrandoIgnacio Catalan-MonzonFernando Frutos-VivarJorge JimenezCarmen Rodríguez-SolisEnric Franquesa-GonzalezGuillermo Pérez AcostaLuciano Santana CabreraJuan Pablo Aviles ParraFrancisco Muñoyerro GonzalezMaria Lorente del Carmen ConesaIgnacio Yago Martinez VarelaOrville Victoriano Baez PraviaMaria Cruz Martin DelgadoCarlos Munoz de CaboAna-Maria IoanCesar Perez-CalvoArnoldo SantosAne Abad-MotosJavier Ripolles-MelchorBelén Civantos MartinSantiago Yus TeruelJuan Higuera LucasAaron Blandino OrtizRaúl de Pablo SánchezJesús Emilio Barrueco-FrancioniLorena Forcelledo EspinaJosé Bonell-GoytisoloIñigo SalaverriaAntonia Socias MirEmilio Rodriguez-RuizVirginia Hidalgo ValverdePatricia Jimeno CuberoFrancisca Arbol LindeNieves Cruza LeganesJuan Maria RomeuPablo ConchaJosé Angel Berezo-GarciaVirginia FraileCristina Cuenca-RubioDavid Pérez-TorresAinhoa SerranoClara Martínez ValeroAndrea Ortiz SunerLeire LarrañagaNoemi LegaristiGerardo FerrignoSafa KhlafallaRosita Bihariesingh-SanchitFrank ZoernerJonathan GripKristina KilsandJohan MårtenssonJonas ÖsterlindMagnus von SethJohan BerkiusSamuele CerutiAndrea GlottaSeval IzdesIşıl Özkoçak TuranAhmet CosarBurcin HalacliNecla DereliMehmet YilmazTürkay AkbasGülseren ElaySelin EyüpoğluYelíz BílírKemal Tolga SaraçoğluEbru KayaAyca Sultan SahinPervin Korkmaz EkrenTuğçe MengiKezban Ozmen SunerYakup TomakAhmet ErogluAsad AlsabbahKatie HanlonKevin GervinSean McmahonSamantha HaganCaroline HigenbottamRandeep MullhiLottie PoultonTomasz TorlinskiAllen GarethNick TrumanGopal VijayakumarChris HallAlasdair JubbLenka CagovaNicola JonesSam GrahamNicole RobinAmanda CowtonAdrian DonnellyNatalia SingatullinaMelanie KentCarole BoulangerZoë CampbellElizabeth PotterNatalie DuricTamas SzakmanyOrinta KviatkovskeNandor MarczinCaroline EllisRajnish SahaChunda Sri-ChandanaJohn AllanLana MumeljHarish VenkateshVera Nina GotzAnthony CochraneBarbara FicialShruthi KambleNuttha LumlertgulChristopher OddySusan JainGiulia Beatrice CrapelliAikaterini VlachouDavid GoldenSweyn GarriochJeremy HenningGupta LoveleenaMiriam DaveyLina GrauslyteErika Salciute-SimeneMartin CookDanny BarlingPhil BroadhurstSarah PurvisMichael SpiveyBenjamin ShukerIrina GrecuDaniel HardingNatalia SingatullinaJames DeanNathan NielsenSama Al-BayatiMohammed Al-SadawiMariane CharronPeter StubenrauchJairo SantanillaCatherine WentowskiDorothea RosenbergerPolikseni EksarkoRandeep Jawa
• Organismes : Hopital Saint-Louis [AP-HP] Istituto Clinico Humanitas [Milan] Università degli Studi di Milano-Bicocca = University of Milano-Bicocca VU University Medical Center [Amsterdam] Guy's and St Thomas' Hospital [London] SMARRT Study ANZICS Clinical Trials Group Hedenstierna Laboratory, Department of Surgical Sciences Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre] Hypertension pulmonaire : physiopathologie et innovation thérapeutique Groupe de recherche clinique CARMAS (Cardiovascular and Respiratory Manifestations of Acute lung injury and Sepsis) Hypertension pulmonaire : physiopathologie et innovation thérapeutique
• Publié dans Annals of Intensive Care le 23/10/2020

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Résumé : Abstract Background Early mobilisation (EM) is an intervention that may improve the outcome of critically ill patients. There is limited data on EM in COVID-19 patients and its use during the first pandemic wave. Methods This is a pre-planned subanalysis of the ESICM UNITE-COVID, an international multicenter observational study involving critically ill COVID-19 patients in the ICU between February 15th and May 15th, 2020. We analysed variables associated with the initiation of EM (within 72 h of ICU admission) and explored the impact of EM on mortality, ICU and hospital length of stay, as well as discharge location. Statistical analyses were done using (generalised) linear mixed-effect models and ANOVAs. Results Mobilisation data from 4190 patients from 280 ICUs in 45 countries were analysed. 1114 (26.6%) of these patients received mobilisation within 72 h after ICU admission; 3076 (73.4%) did not. In our analysis of factors associated with EM, mechanical ventilation at admission (OR 0.29; 95% CI 0.25, 0.35; p = 0.001), higher age (OR 0.99; 95% CI 0.98, 1.00; p ≤ 0.001), pre-existing asthma (OR 0.84; 95% CI 0.73, 0.98; p = 0.028), and pre-existing kidney disease (OR 0.84; 95% CI 0.71, 0.99; p = 0.036) were negatively associated with the initiation of EM. EM was associated with a higher chance of being discharged home (OR 1.31; 95% CI 1.08, 1.58; p = 0.007) but was not associated with length of stay in ICU (adj. difference 0.91 days; 95% CI − 0.47, 1.37, p = 0.34) and hospital (adj. difference 1.4 days; 95% CI − 0.62, 2.35, p = 0.24) or mortality (OR 0.88; 95% CI 0.7, 1.09, p = 0.24) when adjusted for covariates. Conclusions Our findings demonstrate that a quarter of COVID-19 patients received EM. There was no association found between EM in COVID-19 patients' ICU and hospital length of stay or mortality. However, EM in COVID-19 patients was associated with increased odds of being discharged home rather than to a care facility. Trial registration ClinicalTrials.gov: NCT04836065 (retrospectively registered April 8th 2021).

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• Type de publi. : Article dans une revue
• Date de publi. : 11/11/2023
• Auteurs : Xavier CorveleynCamille CorbelRoxanne FabreRadia ZeghariKathy DujardinPhilippe RobertValeria Manera
• Organismes : Maison des Sciences de l'Homme et de la Société Sud-Est Laboratoire d'Anthropologie et de Psychologie Cliniques, Cognitives et Sociales Laboratoire d'Anthropologie et de Psychologie Cliniques, Cognitives et Sociales Cognition Behaviour Technology Cognition Behaviour Technology Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 Centre Mémoire de Ressources et de Recherche [Nice] Centre Mémoire de Ressources et de Recherche [Nice] Cognition Behaviour Technology
• Publié dans Frontiers in Psychology le 02/11/2020

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Résumé : Objective: Apathy is present in many brain disorders, but it is also prevalent to varying degrees in healthy people. While many tools have been developed to assess levels of apathy in pathology, no standardized measure of apathy in healthy people exists. Method: Therefore, this study aimed to validate the French version of the Apathy Motivation Index (f-AMI). The results of 729 participants were analyzed using an exploratory factorial analysis. Results: Preliminary analyses suggested that the three domains of apathy extracted in the original AMI scale—behavioral activation (BA), social motivation (SM), and emotional sensitivity (ES)—could be found also in the f-AMI. A further exploratory analysis showed that a higher number of factors could be extracted, particularly for women. Specifically, both social and emotional factors could be divided into two sub-factors: (1) social motivation toward strangers or toward an acquaintance and (2) self-directed emotional sensitivity directed toward others. Regarding construct validity, the scores of f-AMI were correlated with the French Dimensional Apathy Scale results. Concerning the divergent validity, emotional sensitivity in apathy is different from depression, anhedonia, and fatigue levels. Conclusion: These results suggest that the f-AMI can be used to assess levels of apathy in healthy adults.

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Fichiers liés : fpsyg-14-1252965.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 09/11/2023
• Auteurs : Shengli TaoWigneron J.-P.Jérôme ChaveZhiyao TangZhiheng WangJiangling ZhuQinghua GuoYi LiuPhilippe Ciais
• Organismes : College of Urban and Environmental Sciences [Beijing] Interactions Sol Plante Atmosphère Evolution et Diversité Biologique Peking University [Beijing] Peking University [Beijing] Peking University [Beijing] Peking University [Beijing] University of New South Wales [Sydney] Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette]
• Publié dans Nature Climate Change le 30/10/2020

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Résumé : The resilience of the Amazon rainforest to climate and land-use change is crucial for biodiversity, regional climate and the global carbon cycle. Deforestation and climate change, via increasing dry-season length and drought frequency, may already have pushed the Amazon close to a critical threshold of rainforest dieback. Here, we quantify changes of Amazon resilience by applying established indicators (for example, measuring lag-1 autocorrelation) to remotely sensed vegetation data with a focus on vegetation optical depth (1991-2016). We find that more than three-quarters of the Amazon rainforest has been losing resilience since the early 2000s, consistent with the approach to a critical transition. Resilience is being lost faster in regions with less rainfall and in parts of the rainforest that are closer to human activity. We provide direct empirical evidence that the Amazon rainforest is losing resilience, risking dieback with profound implications for biodiversity, carbon storage and climate change at a global scale.The Amazon rainforest is increasingly under pressure from climate change and deforestation. The resilience of three-quarters of the forest, particularly in drier areas or close to human activity, has been decreasing since the 2000s, indicating that the system may be approaching a tipping point.

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Fichiers liés : s41558-023-01853-8.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 08/11/2023
• Auteurs : Nathalie OllatJean-Pascal TandonnetMarina de MiguelClément Saint CastVirginie LauvergeatJoseph TranBernadette RubioNabil GirolletPierre-François BertMaria LafarguePhilippe VivinSarah J. CooksonDaniel EsmenjaudElisa Marguerit
• Organismes : Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Interactions Biotiques et Santé Végétale Ecophysiologie et Génomique Fonctionnelle de la Vigne

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Résumé : Rootstocks were the first sustainable and environmentally friendly strategy to cope with a major threat for Vitis vinifera cultivation. In addition to providing Phylloxera resistance, they play an important role in protecting against other soil-borne pests, such as nematodes, and in adapting V. vinifera to limiting abiotic conditions. Today viticulture has to adapt to ongoing climate change whilst simultaneously reducing its environmental impact. In this context, rootstocks are a central element in the development of agro-ecological practices that increase adaptive potential with low external inputs. Despite the apparent diversity of the Vitis genus, only few rootstock varieties are used worldwide and most of them have a very narrow genetic background. This means that there is considerable scope to breed new, improved rootstocks to adapt viticulture for the future. However, in comparison to the extensive research effort devoted to fruit varieties, there is little scientific knowledge to support grapevine rootstock breeding. Since grafting became widespread in viticulture, very few studies have been done on the genetic architecture of the relevant traits in rootstocks, even for resistance to Phylloxera or grafting ability. The current presentation will provide an overview of our knowledge on the genetics of specific rootstock traits, covering resistance to Phylloxera and nematodes, rooting and grafting abilities, and adaptation to drought and salinity. An attempt to list the resources and initiatives at the international level will be made. Acknowledgements: The research for rootstock breeding in Bordeaux has been supported over the years by numerous funding agencies and has benefited from the support of the wine industry. Louis Bordenave, Bernard Douens, Jean-Pierre Petit, Cyril Hévin and Nicolas Hocquard are to be acknowledged for their great involvement in the management of genetic resources and the monitoring of plant material.

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• Type de publi. :
• Date de publi. : 08/11/2023
• Auteurs : Chloé OllivierJérôme DemartyJordi EtchanchuHélène BarralSamuel BitaudPascal BrunetSimon Damien CarrièreJean Philippe ChazarinLéna ColletA. DezetterNesrine FarhaniPierre FischerMaurice GuillodHervé JourdeBehshad KoohborI. MainassaraPierre MarchandMonique OïJean Louis PerrinBrune Raynaud--SchellMarine RousseauCharlie VoisinNanée Chahinian
• Organismes : Hydrosciences Montpellier Centre d'études spatiales de la biosphère Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Milieux Environnementaux, Transferts et Interactions dans les hydrosystèmes et les Sols Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Institut de chimie des milieux et matériaux de Poitiers [UMR 7285] Hydrosciences Montpellier Hydrosciences Montpellier GeoRessources GeoRessources Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier

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Résumé : Bassin versant du Rieu Massel, Sud-Est de la France, piémont Cévenol Les chercheurs d'HSM s'investissent depuis quelques années dans l'étude du fonctionnement du bassin versant du Rieu Massel. Ce cours d'eau intermittent est un affluent du Vidourle. Les débits observés au niveau du barrage de Ceyrac varient de 0 à plus de 200m 3 /s. Cet hydrosystème complexe présente des défis pour les éco-hydrologues, les hydrologues et hydrogéologues de l'UMR. Ce site est également un formidable terrain pédagogique pour les étudiants du master EAU de l'Université de Montpellier.

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Fichiers liés : PrésentationA0_ICOS_nov_2023c-1.pdf

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• Type de publi. :
• Date de publi. : 08/11/2023
• Auteurs : Etienne R. PatinAnder del Sol IturraldeUsue Pérez-LopezPierre GastouJean-Pascal TandonnetElisa MargueritPhilippe VivinNathalie OllatMarina de Miguel
• Organismes : Ecophysiologie et Génomique Fonctionnelle de la Vigne Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne] Distributed Systems Group [UPV/EHU] Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne] Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne

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Résumé : Grapevines are grown mainly as grafts worldwide, but the rootstocks most commonly used were selected between the late 19th and early 20th centuries and are based on reduced genetic diversity[1]. In the context of climate change, it is indeed urgent to diversify the range of rootstocks with genotypes much more adapted to drier environments, than the existing ones[2]. The aim of this study was to evaluate the potential of new genetic resources for grapevine rootstock breeding programs. For this purpose, 12 American and Asian wild Vitis species (3 to 5 accessions per species = 50 accessions) were evaluated for their rooting ability and drought response. The plants were submitted to different irrigation treatments (moderate water deprivation vs well-watered) in a phenotyping platform for one month. Evaluation of gas exchange related traits and vegetative growth was performed during the experiment. Rooting ability and root morphology at different developmental stages were also recorded using image analysis using Rhizovision and SmartRoot softwares. We used mixed models to estimate broad-sense heritability. We observed high genetic variation among and within species for root traits and aerial drought response. Genetic correlations between aerial traits in response to drought and constitutive root morphology allowed us to select interesting accessions to be used in breeding programs. The 50 evaluated accessions have been grafted in 2023 to evaluate the interactions with the scion when used as rootstocks. Acknowledgements: This study was supported by funding from INRAE, the Nouvelle-Aquitaine region (project VitiScope) and the CNIV. We acknowledge Maria Lafargue, Cyril Hevin, Nicolas Hocquard and Jean-Pierre Petit for their help with the plant material preparation. References: 1) Riaz, S. et al. (2019) Genetic diversity and parentage analysis of grape rootstocks. Theorethical and Applied Genetics 132, 1847–1860. 2) Marín, D. et al.(2021) Challenges of viticulture adaptation to global change : Tackling the issue from the roots. Australian Journal of Grape and Wine Research, 27(1), Article 1.

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