Philippe JEAN-PIERRE

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 25/09/2023
• Auteurs : Moindjie SoilihiDaniela MunteanuJean-Luc AutranMartin DentanPhilippe MoreauFrancis-Pierre PellissierBenjamin SantraineJérôme BucalossiVictor MalherbeThomas TheryGilles GasiotPhilippe RocheMatteo CecchettoRubén García Alía
• Organismes : Institut des Matériaux, de Microélectronique et des Nanosciences de Provence Institut des Matériaux, de Microélectronique et des Nanosciences de Provence Institut des Matériaux, de Microélectronique et des Nanosciences de Provence CEA Cadarache CEA Cadarache CEA Cadarache CEA Cadarache CEA Cadarache STMicroelectronics [Crolles] STMicroelectronics [Crolles] STMicroelectronics [Crolles] STMicroelectronics [Crolles] CERN [Genève] CERN [Genève]

---

Résumé : We conducted real-time SER measurements on bulk 65 nm SRAMs in the WEST tokamak during long pulse deuterium-deuterium plasma discharges (~60 s), evidencing bursts of SEUs during the most efficient shots and 12% of MCU events.

---

Fichiers liés : RADECS_2023_HAL.pdf

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 25/09/2023
• Auteurs : Théo MazureGeorges-Marie SaulnierVincent ChanudetManon BajardFabien ArnaudPierre SabatierJean-Philippe Jenny
• Organismes : Université Savoie Mont Blanc Centre Alpin de Recherche sur les Réseaux Trophiques et Ecosystèmes Limniques Environnements, Dynamiques et Territoires de Montagne Electricité de France Environnements, Dynamiques et Territoires de Montagne Environnements, Dynamiques et Territoires de Montagne Environnements, Dynamiques et Territoires de Montagne Centre Alpin de Recherche sur les Réseaux Trophiques et Ecosystèmes Limniques

---

Résumé : Human land use changes have altered soil erosion for millennia with extensive consequences on terrestrial and aquatic ecosystems as well as on biogeochemical cycles along the land-ocean continuum. Despite their great importance, past erosion trends have high uncertainties limiting quantitative estimates of long-term erosion dynamics. Here, we applied a new approach combining well-dated paleo-records of soil erosion from lake sediments and a spatially distributed semi-empirical model to simulate annual soil erosion in six lake watershed systems in the Northwestern Alps during the Holocene. Progressive and abrupt changes in soil erosion are detected in the six watersheds. Progressive erosion explains most of the soil exports observed during the Early to Mid-Holocene period (from 11,700 to 3000 cal. yr. BP), while transient erosion crises (i.e., periods of abrupt increase in the erosion rates spanning approximately 1000 ± 500 years) led to massive soil losses during the Late Holocene period (from 3000 to 1000 cal. yr. BP). Our coupled approach of proxy-model reconstruction shows that the transient erosion crises represent the half of the total soil erosion exports during the Holocene. These estimates defy current representations of large-scale soil erosion during the Holocene that do not consider transient erosion crises, hence potentially underestimating the anthropogenic perturbation of lateral fluxes and fate along the land-ocean continuum. Our results further suggest that erosion and/or land cover proxies need to be consistently integrated into model approaches when attempting to estimate past variations in mass exports from terrestrial to aquatic ecosystems over centennial to millennial timescales.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 21/09/2023
• Auteurs : Sébastien BourdinJohn MoodieNora Sánchez GassenDavid EversFulvio AdobatiMounir AmdaoudGiuseppe ArcuriEmanuela CastiVictoire CottereauIonel MunteleHajnalka LőcseiCorneliu IaţuPhilippe Jean-PierreFrançois HermetNadine LevrattoLinnea LöfvingEva Coll-MartínezYannis PsycharisViktor SaleniusZsuzsa Remete
• Organismes : Métis Lab EM Normandie Pôle de recherche interdisciplinaire en sciences du management EconomiX EconomiX Laboratoire d'Etude et de Recherche sur l'Economie, les Politiques et les Systèmes Sociaux
• Publié dans Regional Studies le 28/10/2020

---

Résumé : The COVID-19 pandemic, originating as a health crisis but quickly expanding to other social spheres, had significant and asymmetric impacts across Europe, which potentially undermine territorial cohesion. Much has been written about the overall impact of the pandemic on the underlying thematic and budgetary focus of European Union-level policies with respect to territorial cohesion. However, it remains unclear to what extent policies implemented at regional and local levels in response to the crisis also contribute to territorial cohesion. To address this, we investigated the extent to which the pandemic constituted a ‘window of opportunity’ for developing innovative policies furthering territorial cohesion policy goals and objectives within member states, and assessed whether the crisis led to more collaborative, integrative and holistic policymaking. To this end, the research examined policy responses across 14 European regions by means of a mixed-method case study approach, including the analysis of relevant policy documents and over 100 semi-structured interviews with key stakeholders. We show that the pandemic led to the introduction of new short-term social policies to reduce socio-economic disparities produced by COVID-19 and accelerated the implementation of green and smart policies. Additionally, the crisis fostered greater collaboration between public authorities and key stakeholders, and between regional and municipal public authorities, although the long-term impact is uncertain. These findings could have policy implications for other crisis situations. Moreover, they suggest that territorial cohesion policies should be tailored to empower regions and local governments to use systemic shocks to draft and implement proactive social, economic and environmental policies.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 20/09/2023
• Auteurs : Petros AndrikopoulosJudith Aron-WisnewskyRima ChakarounAntonis MyridakisKristoffer ForslundTrine NielsenSolia AdriouchBridget HolmesJulien ChillouxSara Vieira-SilvaGwen FalonyJoe‐elie SalemFabrizio AndreelliEugeni BeldaJulius KieswichKanta ChechiFrancesc Puig-CastellvíMickael ChevalierEmmanuelle Le ChatelierMichael T OlanipekunLesley HoylesRenato AlvesGerard HelftRichard IsnardLars KøberLuis Pedro CoelhoChristine RouaultDominique GauguierJens Peter GøtzeEdi PriftiPhilippe FroguelRohia AliliEhm Astrid Andersson GalijatovicOlivier BarthelemyJean-Philippe BastardJean-Paul BatissePierre Bel-LassenMagalie BerlandRanda BittarHervé M. BlottiereFrederic BosquetRachid BoubritOlivier BourronMickael CamusCecile CianguraJean-Philippe ColletArne DietrichMorad DjebbarAngélique DoréLine EngelbrechtsenLeopold FezeuSebastien FromentinNicolas PonsMarianne GraineCaroline GrünemannAgnes HartemannBolette HartmannMalene HornbakSophie JaqueminetNiklas Rye JørgensenHanna JulienneJohanne JustesenJudith KammerNikolaj KarupRuby KozlowskiMichael KuhnVéronique LejardIvica LetunicFlorence LevenezLajos MarkoLaura Martinez-GiliRobin MasseyNicolas MaziersLucas Moitinho-SilvaGilles MontalescotAna Luisa NevesLaetitia Pasero Le PavinFrancoise PoussetAndrea Rodriguez-MartinezSebastien SchmidtTatjana SchützLucas SilvaJohanne SilvainMathilde SvendstrupTimothy D SwartzThierry VanduyvenbodenEric O. VergerStefanie WaltherJean-Daniel ZuckerFredrik BäckhedHenrik VestergaardTorben HansenJean-Michel OppertMatthias BlüherJens NielsenJeroen RaesPeer BorkMuhammad M YaqoobMichael StumvollOluf PedersenS. Dusko EhrlichKarine ClémentMarc-Emmanuel Dumas
• Organismes : Toxicité environnementale, cibles thérapeutiques, signalisation cellulaire Metabolic functional (epi)genomics and molecular mechanisms involved in type 2 diabetes and related diseases - UMR 8199 - UMR 1283 Imperial College London
• Publié dans Nature Communications le 23/10/2020

---

Résumé : Abstract The host-microbiota co-metabolite trimethylamine N -oxide (TMAO) is linked to increased cardiovascular risk but how its circulating levels are regulated remains unclear. We applied “explainable” machine learning, univariate, multivariate and mediation analyses of fasting plasma TMAO concentration and a multitude of phenotypes in 1,741 adult Europeans of the MetaCardis study. Here we show that next to age, kidney function is the primary variable predicting circulating TMAO, with microbiota composition and diet playing minor, albeit significant, roles. Mediation analysis suggests a causal relationship between TMAO and kidney function that we corroborate in preclinical models where TMAO exposure increases kidney scarring. Consistent with our findings, patients receiving glucose-lowering drugs with reno-protective properties have significantly lower circulating TMAO when compared to propensity-score matched control individuals. Our analyses uncover a bidirectional relationship between kidney function and TMAO that can potentially be modified by reno-protective anti-diabetic drugs and suggest a clinically actionable intervention for decreasing TMAO-associated excess cardiovascular risk.

---

Fichiers liés : s41467-023-39824-4-2.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 20/09/2023
• Auteurs : Massilia AbbasMeriem MaalejFerran Nieto-FabregatMichel ThépautJean-Philippe KlemanIsabel AyalaAntonio MolinaroJean-Pierre SimorreRoberta MarchettiFranck FieschiCédric Laguri
• Organismes : Institut de biologie structurale Dipartimento di Scienze Chimiche Dipartimento di Scienze Chimiche Institut de biologie structurale Institut de biologie structurale Institut de biologie structurale Dipartimento di Scienze Chimiche Institut de biologie structurale Dipartimento di Scienze Chimiche Institut de biologie structurale Institut de biologie structurale
• Publié dans PNAS Nexus le 23/05/2022

---

Résumé : Lipopolysaccharides are a hallmark of gram-negative bacteria, and their presence at the cell surface is key for bacterial integrity. As surface-exposed components, they are recognized by immunity C-type lectin receptors present on antigen-presenting cells. Human macrophage galactose lectin binds Escherichia coli surface that presents a specific glycan motif. Nevertheless, this high-affinity interaction occurs regardless of the integrity of its canonical calcium-dependent glycan-binding site. NMR of macrophage galactose-type lectin (MGL) carbohydrate recognition domain and complete extracellular domain revealed a glycan-binding site opposite to the canonical site. A model of trimeric macrophage galactose lectin was determined based on a combination of small-angle X-ray scattering and AlphaFold. A disulfide bond positions the carbohydrate recognition domain perpendicular to the coiled-coil domain. This unique configuration for a C-type lectin orients the six glycan sites of MGL in an ideal position to bind lipopolysaccharides at the bacterial surface with high avidity.

---

Fichiers liés : pgad310.pdf

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 11/09/2023
• Auteurs : Quentin BerlingardMaxime MoulinJean-Philippe MichelThibaud FacheIsmael CharletChristophe PlantierZdenek ChalupaJ. Lugo-AlvarezJean-Pierre RaskinLouis HutinMikael Casse
• Organismes : Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Institut de Microélectronique, Electromagnétisme et Photonique - Laboratoire d'Hyperfréquences et Caractérisation Département Composants Silicium Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Département Composants Silicium Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Département Composants Silicium Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Université Catholique de Louvain = Catholic University of Louvain Département Composants Silicium Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information

---

Résumé : We investigate the temperature-dependent RF response of different types of silicon substrates (standard, highresistivity and trap-rich) through measurements performed on BEOL-embedded inductors from room temperature down to 7K. For the first time, we observe that the performance ranking between substrates, well known at 300K, is altered in cryogenic conditions (T<50K). Based on a parametric analysis of the Qfactor, we attribute this behavior to the heightened importance at low T of counteracting a parasitic surface conduction (PSC) forming at the interface between the substrate and the dielectric.

---

Source

---

• Type de publi. :
• Date de publi. : 09/09/2023
• Auteurs : Camille FletcherAlice HadchouelCaroline ThumerelleManon FleuryNouha JedidiMyriam BenhamidaKatia BessaciRaphaël BorieTiphaine BilhoueeJacques BrouardAurélie CantaisAnnick ClémentLaurianne CoutierPierrick CrosMarie-Laure DalphinChristophe DelacourtRalph EpaudEric DeneuvilleAntoine DeschildreJean-Christophe DubusCarole EgronMichaël FayonAgnes FinaAude ForgeronElsa GachelinFrancois GalodeIsabelle GibertiniLisa Giovannini-ChamiTamazoust GuiddirAudrey HerzogVéronique HoudouinEglantine HulloPierre-Henri JarreauGeraldine LabouretAlice LadauradeLaurence Le Clainche VialaChristophe MarguetAlexandra Masson-RouchaudJulie MazenqCaroline PerissonCinthia RamesPhilippe ReixMarie-Catherine RenouxLéa RoditisCyril SchweitzerAurélie TatopoulosPascale Trioche EberschweilerFrançoise TroussierClémentine VigierLaurence WeissMarie LegendreCamille LouvrierAlix de BecdelièvreAurore Coulomb-L'HermineChiara SileoHubert Ducou Le PointeLaureline BerthelootCeline DelestrainNadia Nathan
• Organismes : CHU Trousseau [APHP] Hôpital Necker - Enfants Malades [AP-HP] Institut Necker Enfants-Malades Centre Hospitalier Régional Universitaire [CHU Lille] CHU Trousseau [APHP] CHU Trousseau [APHP] Centre Hospitalier Universitaire de Nantes = Nantes University Hospital Hôpital universitaire Robert Debré [Reims] AP-HP - Hôpital Bichat - Claude Bernard [Paris] Centre Hospitalier Universitaire de Nantes = Nantes University Hospital CHU Caen Normandie – Centre Hospitalier Universitaire de Caen Normandie Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] CHU Trousseau [APHP] Centre Hospitalier Lyon Sud [CHU - HCL] Centre Hospitalier Régional Universitaire de Brest Centre Hospitalier Régional Universitaire de Besançon Hôpital Necker - Enfants Malades [AP-HP] Institut Necker Enfants-Malades Centre Hospitalier Intercommunal de Créteil Hôpital Sud [CHU Rennes] Centre Hospitalier Régional Universitaire [CHU Lille] Assistance Publique - Hôpitaux de Marseille CHU Estaing [Clermont-Ferrand] CHU de Bordeaux Pellegrin [Bordeaux] Hôpitaux Pédiatriques de Nice Lenval Centre Hospitalier Le Mans (CH Le Mans) Centre Hospitalier Universitaire de La Réunion Centre Hospitalier Universitaire de Bordeaux Centre Hospitalier Régional Universitaire de Tours Hôpitaux Pédiatriques de Nice Lenval Hôpital Bicêtre [AP-HP, Le Kremlin-Bicêtre] Centre Hospitalier Universitaire [Strasbourg] AP-HP Hôpital universitaire Robert-Debré [Paris] Centre Hospitalier Universitaire [CHU Grenoble] AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris] Centre Hospitalier Universitaire de Toulouse Centre Hospitalier Régional Universitaire de Besançon AP-HP Hôpital universitaire Robert-Debré [Paris] CHU Rouen CHU Limoges Assistance Publique - Hôpitaux de Marseille Centre Hospitalier Universitaire de La Réunion CHU Amiens-Picardie Hospices Civils de Lyon CHU Montpellier = Montpellier University Hospital Centre Hospitalier Universitaire de Toulouse Centre Hospitalier Régional Universitaire de Nancy Centre Hospitalier Régional Universitaire de Nancy Centre Hospitalier Régional Universitaire de Nancy Centre Hospitalier Universitaire d'Angers Hôpital Sud [CHU Rennes] Centre Hospitalier Universitaire [Strasbourg] CHU Trousseau [APHP] Maladies génétiques d'expression pédiatrique CHU Trousseau [APHP] Maladies génétiques d'expression pédiatrique Centre Hospitalier Intercommunal de Créteil CHU Trousseau [APHP] CHU Trousseau [APHP] CHU Trousseau [APHP] Hôpital Necker - Enfants Malades [AP-HP] Centre Hospitalier Intercommunal de Créteil CHU Trousseau [APHP] Maladies génétiques d'expression pédiatrique

---

Résumé : Introduction: Interstitial lung disease ( LD) in children (chlLD) is rare and Often severe. This study aims at analyzing the ep demiology of chlLD in France from 2000 to 2022. Methods: This study was retrospective and multicentric, A questionnaire was sent to all the RespiRare centers to collect the clinical, radiological, biological, histological and genetic data of the patients. Results: 617 patients (0-18 years) were included in 42 centers. 84 patients were excluded. The median age at diagnosis was 0.3 years with 17% of familial forms, The main investigations performed were: chest CT scan (92%), bronchoalveolar avage (52%), genetic ana ysis (78%), lung biopsy (23%). The main treatments were: corticosteroids (93%), oxygen therapy (52.2%), enteral nutrition (29%), hydroxychloroqu•ne (16%), azThromycin (26%), immunosuppressive drugs (210/0). The follovFup time was from O to 18,9 years (median duration 3,5years). The survival rate at 5 years was 68%. The overall incidence and preva ence were estimated at 38/million and 35/million children respectively. Conclusion: This arge chlLD epidemiological study confirms the Span •sh data with a higher incidence and prevalence than previous y described. The arge amount Of phenotypic data collected will allow better understanding ch LD and harmonizing their management.

---

Fichiers liés : E-poster ERS Epidemio PID_Camille FLETCHER.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 07/09/2023
• Auteurs : Robert CaiazzoPierre BauvinCamille MarciniakPatrick SauxGeoffrey JacqminRaymond ArnouxSalomon BenchetritJerome DargentJean-Marc ChevallierVincent FreringJean GugenheimDavid LechauxSimon MsikaAdrien SterkersPhilippe TopartGrégory BaudFrançois Pattou
• Organismes : Centre Hospitalier Régional Universitaire [CHU Lille] Centre Hospitalier Régional Universitaire [CHU Lille] Centre Hospitalier Régional Universitaire [CHU Lille] Scool Centre de Recherche en Informatique, Signal et Automatique de Lille - UMR 9189 Centre Hospitalier Régional Universitaire [CHU Lille] Centre Hospitalier Régional Universitaire [CHU Lille]
• Publié dans Annals of Surgery le 26/10/2020

---

Résumé : Objective: To investigate the way robotic assistance affected rate of complications in bariatric surgery at expert robotic and laparoscopic surgery facilities. Background: While the benefits of robotic assistance were established at the beginning of surgical training, there is limited data on the robot’s influence on experienced bariatric laparoscopic surgeons. Methods: We conducted a retrospective study using the BRO clinical database (2008–2022) collecting data of patients operated on in expert centers. We compared the serious complication rate (defined as a Clavien score≥3) in patients undergoing metabolic bariatric surgery with or without robotic assistance. We used a directed acyclic graph to identify the variables adjustment set used in a multivariable linear regression, and a propensity score matching to calculate the average treatment effect (ATE) of robotic assistance. Results: The study included 35,043 patients [24,428 sleeve gastrectomy (SG); 10,452 Roux-en-Y gastric bypass (RYGB); 163 single anastomosis duodenal-ileal bypass with sleeve gastrectomy (SADI-S)], with 938 operated on with robotic assistance (801 SG; 134 RYGB; 3 SADI-S), among 142 centers. Overall, we found no benefit of robotic assistance regarding the risk of complications (average treatment effect=−0.05, P =0.794), with no difference in the RYGB+SADI group ( P =0.322) but a negative trend in the SG group (more complications, P =0.060). Length of hospital stay was decreased in the robot group (3.7±11.1 vs 4.0±9.0 days, P <0.001). Conclusions: Robotic assistance reduced the length of stay but did not statistically significantly reduce postoperative complications (Clavien score≥3) following either GBP or SG. A tendency toward an elevated risk of complications following SG requires more supporting studies.

---

Source

---

• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 07/09/2023
• Auteurs : Shreyasi AcharyaDagmar AdamovaGianluca Aglieri RinellaMichelangelo AgnelloNeelima AgrawalZubayer AhammedShakeel AhmadSang Un AhnIshaan AhujaAlexander AkindinovMohammad Al-TuranyDmitry AleksandrovBruno AlessandroHaidar Masud AlfandaJose Ruben Alfaro MolinaBushra AliAndrea AliciNegin AlizadehvandchaliAnton AlkinJohan AlmeGiacomo AloccoTorsten AltAnna Rita AltamuraIgor AltsybeevMustafa AnaamCristian AndreiNicodemos AndreouAnton AndronicVenelin AnguelovFederico AntinoriPietro AntonioliNicole ApadulaLaurent AphecetcheHarald AppelshaeuserCarolina ArataSilvia ArcelliMauro ArestiRoberta ArnaldiJhoao Gabriel Martins Campos Almeida ArneiroIonut Cristian ArseneMesut ArslandokAndre AugustinusRalf Peter AverbeckMohd Danish AzmiHitoshi BabaAngela BadalaJoonsuk BaeYongwook BaekXiaozhi BaiRaphaelle Marie BailhacheYoshini BailungAlessandro BalbinoAlberto BaldisseriBartosz BalisDebjani BanerjeeZarina BanooRoberto BarberaFrancesco BarileLuca BarioglioMaria BarlouBanajit BarmanGergely Gabor BarnafoldiLee Stuart BarnbyValerie Ramillien BarretLeonardo Barreto de Oliveira CamposClara BartelsKlaus BarthEsther BartschNicole BastidSumit BasuGuillaume BatigneDaniel BattistiniBoris BatyunyaDibakar BauriJose Luis Bazo AlbaIan Gardner BeardenCaitlin BeattiePascal BechtDebadatta BeheraIouri BelikovAilec Bell HechavarriaFrancesca BelliniRene BellwiedSvetlana BelokurovaYael Antonio Vasquez BeltranGyula BencediStefania Maria BeoleYaroslav BerdnikovAnastasia BerdnikovaLuisa BergmannMihaela Gabriela BesoiuLatchezar BetevPartha Pratim BhaduriAnju BhasinMohammad Asif BhatBuddhadeb BhattacharjeeLivio BianchiNicola BianchiJaroslav BielcikJana BielcikovaJacek Bogumil BiernatAlexandre Patrick BigotAnte BilandzicGabor BiroSaikat BiswasNicolas BizéJustin Thomas BlairDmitry BlauMihail Bogdan BlidaruNora BluhmeChristoph BlumeGianluigi BocaFriederike BockTea BodovaAlexey BogdanovStefano BoiJeongsu BokLaszlo BoldizsarMarek BombaraPeter Matthew BondGermano BonomiHerve BorelAlexander BorissovAndres Gerardo Borquez CarcamoHannah BossiElena BottaYoussef El Mard BouzianiLars BratrudPeter Braun-MunzingerMarco BregantMichal BrozGiuseppe Eugenio BrunoMatthew Daniel BucklandDmitry BudnikovHenner BueschingStefania BufalinoPaul Alois BuhlerNazar BurmasovEdith Zinhle ButheleziAleksandr BylinkinSebastian Adam BysiakMengke CaiHelen Louise CainesAlberto CalivaErnesto Calvo VillarJuan Manuel Mejia CamachoPaolo CameriniFabio de Moraes CanedoMihai CarabasAitor Amatriain CarballoFrancesca CarnesecchiRobin Albert Andre CaronLeopoldo Abranches de CarvalhoJavier Ernesto Castillo CastellanosFabio CatalanoCesar Ceballos SanchezIrakli ChakaberiaPritam ChakrabortySinjini ChandraSylvain ChapelandMarielle ChartierSubhasis ChattopadhyaySukalyan ChattopadhyayTonatiuh Garcia ChavezTiantian ChengCvetan Valeriev CheshkovBrigitte CheynisVasco Miguel Chibante BarrosoDavid Dobrigkeit ChinellatoEmma Sophia ChizzaliJaeyoon ChoSoyeon ChoPeter ChochulaDhrubajyoti ChoudhuryPanagiotis ChristakoglouChristian Holm ChristensenPeter ChristiansenTatsuya ChujoMario CiaccoCorrado CicaloFederico CindoloMichael Rudolf CiupekGiulia ClaiFabio Filippo ColamariaJonathan Samuel ColburnDomenico ColellaManuel ColocciMatteo ConcasG. Conesa BalbastreZaida Conesa del ValleGiacomo ContinJesus Guillermo Contreras NunoMaurice CoquetPietro CorteseMauro Rogerio CosentinoFilippo CostaSusanna CostanzaCorentin CotJana CrkovskaPhilippe CrochetReynier Cruz TorresPengyao CuiAndrea DaineseMeike Charlotte DanischAndrea DanuProttay DasProttoy DasSupriya DasArchita Rani DashSadhana DashHector David Regules MedelAnnalisa de CaroGiacinto de CataldoJan de CuvelandAlessandro de FalcoDaniele de GruttolaNora de MarcoChiara de MartinSalvatore de PasqualeRohaan DebRaffaele del GrandeLuigi Dello StrittoWenjing DengPreeti DhankherDomenico Di BariAntonio Di MauroBatoul DiabRaul Arteche DiazThomas DietelYanchun DingJanik DitzelRoberto DiviaDhruv Utpalkumar DixitOeystein DjuvslandUliana DmitrievaAlexandru Florin DobrinBenjamin DonigusJan Michal DubinskiAndrea DublaSandeep DudiPascal DupieuxMartin DurkacNatalia DzalaiovaTabea Maria EderRaymond James EhlersFlorian EisenhutRen EjimaDomenico EliaBarbara Ewa ErazmusFrancesca ErcolessiBruno EspagnonGiulio EulisseDavid EvansSergey EvdokimovLaura FabbiettiMattia FagginJulien FaivreFeng FanWenqing FanAlessandra FantoniMarkus FaselPietro FecchioAlessandro FelicielloGrigorii FeofilovArturo Fernandez TellezLucas Ferrandi de OliveiraMarta Bertran FerrerAndrea FerreroChiara FerreroAlessandro FerrettiVictor Jose Gaston FeuillardVendulka FilovaDmitry FinogeevFiorella FiondaErlend FlatlandFernando Antonio FlorAmanda Nicole FloresSiegfried Valentin FoertschIlya FokinSergey FokinEnrico FragiacomoEszter FrajnaUlrich FuchsNicola FunicelloChristophe FurgetArtur FursTakahiro FusayasuJens Joergen GaardhoejeMartino GagliardiAlberto Martin Gago MedinaTanu GahlautCarlos Duarte GalvanDhevan Raja GangadharanParaskevi GanotiJose Maria Garabatos CuadradoAndrea Tavira GarciaJesus Ricardo Alvarado GarciaEdmundo Javier Garcia-SolisCorrado GargiuloPiotr Jan GasikAmrit GautamMaria Beatriz de Leone GayMarie GermainAbderrahmane GhimouzChandrasekhar GhoshMarco GiacaloneGiulia GioachinPaolo GiubellinoPiero GiubilatoAude Marie Camille GlaenzerPeter GlasselEwa GlimosDaniel Jia Qin GohVictor Luis Gonzalez SebastianMarek Boguslaw GorgonKangkan GoswamiSven GotovacVarlen GrabskiLukasz Kamil GraczykowskiEkaterina GreckaAlessandro GrelliCostin GrigorasVladislav GrigoryevSmbat GrigoryanFabrizio GrosaJan Fiete Grosse-OetringhausRaffaele GrossoDavid GrundNadine Alice GruenwaldGabriel Garcia GuardianoRachid GuernaneMaxime Rene Joseph GuilbaudKristjan Herlache GulbrandsenTuba GundemTaku GunjiWenda GuoAnik GuptaRamni GuptaRashi GuptaSergio Paisano GuzmanKatarzyna GwizdzielLaszlo GyulaiCynthia Marie HadjidakisFakhar Ul HaiderSara HaidlovaHideki HamagakiAbdennacer HamdiYounghoon HanBrian Gerald HanleyRyan Patrick HanniganJoachim HansenMd Rihan HaqueJohn William HarrisAustin Vincent HartonHadi HassanDespina HatzifotiadouPhilip HauerLaura Brittany HavenerStefan Thomas HeckelErnst HellbarHaavard HelstrupMarvin HemmerTomas HermanGerardo Antonio Herrera CorralFlorian HerrmannSarah Nina Edwige HerrmannKristin Fanebust HetlandBenedict HeybeckHartmut HillemannsBoris HippolyteFelix Willi HoffmannBas HofmanGeun Hee HongMaximilian HorstAdrian HorzykYongzhen HouPeter Zahariev HristovCharles HughesPatrick HuhnLaura Maria HuhtaThomas HumanicAlek HutsonDirk HutterRadiy IlkaevHira IlyasMotoi InabaGian Michele InnocentiMikhail IppolitovArtem IsakovTommaso IsidoriMd Samsul IslamMarian IvanovMarian IvanovVladimir IvanovKaare Endrup IversenMiroslaw JablonskiBarbara JacakNicolo JacazioPeter Martin JacobsSlavka JadlovskaJan JadlovskySyaefudin JaelaniCristiane JahnkeMonika Joanna JakubowskaMalgorzata Anna JanikThomas JansonSu-Jeong JiShihai JiaAlom Antonio Paz JimenezFlorian JonasDaniel Matthew JonesJohn JowettJerome JungMichael JungAntoine Jean-Simon JuniqueAnton JuskoMaja Jadwiga KabusJetnipit KaewjaiPeter KalinakAnnalena Sophie KalteyerAlexander Philipp KalweitVladimir KaplinAyben Karasu UysalDavid KaratovicOleg KaravichevTatiana KaravichevaPrzemyslaw KarczmarczykEvgeny KarpechevUdo Wolfgang KebschullRalf KeidelDarius KeijdenerMarkus KeilBernhard Franz KetzerSwapnesh Santosh KhadeAhsan Mehmood KhanShaista KhanAlexei KhanzadeevYury KharlovAnisa KhatunArvind KhuntiaBjarte KilengBeomkyu KimChong KimDong Jo KimEun Joo KimJaehyun KimJinsook KimJiyoung KimJunlee KimMinjung KimSe Yong KimTaejun KimKento KimuraStefan KirschIvan KiselSergey KiselevAdam Ryszard KisielJacek Pawel KitowskiJennifer Lynn KlayJochen KleinSpencer Robert KleinChristian Klein-BoesingMatthias KleinerThomas KlemenzAlexander KlugeAnders Garritt KnospeChinorat KobdajThorsten Sven KolleggerAndrey KondratyevNatalia KondratyevaEvgeny KondratyukJoshua Leon KonigStephan Alexander KonigstorferPiotr Jan KonopkaGeorgui Kornakov VanSebastian Dominik KoryciakArtem KotliarovVladimir KovalenkoMarek KowalskiVenelin Valeriev KozhuharovIvan KralikAdela KravcakovaLubos KrcalMarian KrivdaFilip KrizekKatarina Krizkova GajdosovaMartin KroesenMario KrugerDiana Maria KrupovaEvgeny KryshenVit KuceraChristian Claude KuhnPaulus Gerardus KuijerTakuya KumaokaDeekshit KumarLokesh KumarNavneet KumarShyam KumarSourav KunduPodist KurashviliAlexander KurepinAlexey KurepinAlexey KuryakinSvetlana KushpilMin Jung KweonYoungil KwonSarah Louise La PointePaola La RoccaAnantachai LakrathokMassimo LamannaRune LangoyPavel LarionovElisa LaudiLukas LautnerRoman LavickaRamona LeaHyungjun LeeIosif-Charles LegrandGauthier LegrasJohannes LehrbachTomasz Marcin LelekRoy Crawford LemmonIldefonso Leon MonzonMarcel Markus LeschEzra Douglas LesserPeter LevaiXiaomei LiJorgen Andre LienRoman LietavaIris LikmetaBong-Hwi LimSanghoon LimVolker LindenstruthAmelia LindnerChristian LippmannDonghai LiuJian LiuGianni Shigeru Setoue LiveraroIngrid Mckibben LofnesConstantinos LoizidesSandor LokosJohanna LomkerPetra LoncarXavier Bernard LopezErnesto Lopez TorresPengzhong LuFabiola Viridiana LugoJens Robert LuhderMarcello LunardonGrazia LuparelloYugang MaMagnus MagerAntonin MaireMartin Vasilev MakarievMikhail MalaevGiovanni MalfattoreNasir Mehdi MalikQasim Waheed MalikSalman Khurshid MalikLiudmila MalininaDukhishyam MallickNeelkamal MallickGiuseppe MandaglioSushobhan Kumar MandalVladislav MankoFranck MansoVito ManzariYaxian MaoRobert Waclaw MarcjanGiacomo Vito MargagliottiAnselmo MargottiAna Maria MarinChristina MarkertPaolo MartinengoMario Ivan Martinez HernandezGines Martinez-GarciaMaria Paula Martins PalharesSilvia MasciocchiMassimo MaseraAlberto MasoniLaure Marie MassacrierOlaf MassenAnnalisa MastroserioOliver MatonohaSerena MattiazzoAdam Tomasz MatyjaChristoph MayerAntonio Lafuente MazuecosFrancesco MazzaschiMarianna MazzilliJoyful Elma MdhluliYury MelikyanArturo Alejandro Menchaca-RochaJesus Eduardo Munoz MendezElisa MeninnoAnjaly Sasikumar MenonMichal MeresSibaliso MhlangaYasuo MiakeLuca MichelettiDimitar Lubomirov MihaylovKonstantin MikhaylovAditya Nath MishraDariusz Czeslaw MiskowiecAbhi ModakBedangadas MohantyMohammed Mohisin KhanMikael Andreas MolanderShirajum MoniraCindy MordasiniDenise Aparecida Moreira de GodoyIgor MorozovAndreas MorschTeo MrnjavacValeria MucciforaSanjib MuhuriJames Declan MulliganAlice MulliriMarcelo Gameiro MunhozRobert Helmut MunzerHikari MurakamiSean MurrayLuciano MusaJan MusinskyJulian Wojciech MyrchaBharati NaikAnjali Ila NambrathBasanta Kumar NandiRosario NaniaEugenio NappiAdrian Fereydon NassirpourAbhishek NathChristine NattrassMomchil Nikolaev NaydenovAlexandra NeaguAdrian-Eduard NegruLukas NellenRoman NepeivodaSigurd NeseGvozden NeskovicNicola NicassioBorge Svane NielsenEmil Gorm NielsenSergey NikolaevSergey NikulinVladimir NikulinFrancesco NoferiniSeoyoung NohPetr NomokonovJaime NormanNorbert NovitzkyPiotr NowakowskiAlexander NyaninJoakim Ingemar NystrandMasanori OginoSaehanseul OhAlice Elisabeth OhlsonVitaly OkorokovJanusz OleniaczAntonio Carlos Oliveira da SilvaAnna OnnerstadChiara OppedisanoAntonio Ortiz VelasquezJacek Tomasz OtwinowskiMotomi OyaKen OyamaYvonne Chiara PachmayerSonali PadhanDavide PaganoGuy PaicAntonio PalascianoStefano PanebiancoHanseo ParkHyebin ParkJonghan ParkJasper Elias ParkkilaYash PatleyRajendra Nath PatraBiswarup PaulHua PeiThomas PeitzmannXinye PengMichele PennisiStefania PerciballiDmitry Yurevich PeresunkoGuillermo Mesa PerezYury PestovVitalii PetrovMihai PetroviciRafael Peretti PezziStefano PianoMiroslav PiknaPhilippe PillotOmbretta PinazzaLawrence PinskyChiara PintoSilvia PisanoMateusz Andrzej PloskonMirko PlaninicFabian PliquettMartin PoghosyanBoris PolishchukStefano PolitanoNikola PoljakAmalia PopSarah Porteboeuf HoussaisValeriy PozdniakovIrandheny Yoval PozosKshitish Kumar PradhanSidharth Kumar PrasadSuraj PrasadRoberto PreghenellaFrancesco PrinoClaude Andre PruneauIgor PshenichnovMaximiliano PuccioSara PucilloZuzana PugelovaShi QiuLuca QuagliaSimone RagoniAnanya RaiAndry Malala RakotozafindrabeLuciano RamelloFouad RamiSaul Anibal Rodriguez RamirezThibaut Albert RancienMarika RasaSami Sakari RasanenRutuparna RathMax Philip RauchIvan RavasengaKenneth Francis ReadChristian ReckziegelAndreas Ralph RedelbachKrzysztof RedlichCarolina Anna ReetzAttiq Ur RehmanFelix ReidtHaakon Andre Reme-NessZuzana JakubcinovaKlaus Johannes ReygersAndrei RiabovViktor RiabovRiccardo RicciMatthias Rudolph RichterAnton Albert RiedelWerner RieglerAndrea Giovanni RifferoCatalin-Lucian RisteaManuel Viqueira RodriguezMario Rodriguez CahuantziKetil RoeedRoman RogalevElena RogochayaTim Sebastian RogoschinskiDavid Michael RohrDieter RoehrichPablo Fierro RojasSolangel Rojas TorresPrzemyslaw Stefan RokitaGleb RomanenkoFederico RonchettiAntonina RosanoEdgar Dominguez RosasKrystian RoslonAndrea RossiAnkhi RoySubhadeep RoyNicola RubiniDaniela RuggianoRinaldo RuiPawel Grzegorz RussekRoberto RussoAnar RustamovEvgeny RyabinkinYury RyabovAndrzej RybickiHeidi Maria RytkonenJaehyeok RyuWioleta RzesaOskari Antti Matti SaarimakiSamrangy SadhuSergey SadovskiyJon-Are SaetreKarel SafarikPallabi SahaSumit Kumar SahaSwati SahaBaidyanath SahooBhagyarathi SahooRaghunath SahooSarita SahooDushmanta SahuPradip Kumar SahuJogender SainiKlaudia TroppShingo SakaiMalavika Panikkassery SalvanSanjeev Singh SambyalDaniel SamitzIsabella SannaThiago Badaro SaramelaPranjal SarmaValerio SarritzuValentina Mantovani SartiMike SasSawan SawanJohann Joachim SchambachHorst Sebastian ScheidClaudiu Cornel SchiauaRainer Martin SchickerFelix SchlepperAlexander SchmahChristian Joachim SchmidtHans Rudolf SchmidtMarten Ole SchmidtMartin SchmidtNicolas SchmidtAustin Robert SchmierRomain SchotterAlexander SchroterJurgen SchukraftKai Oliver SchwedaGilda ScioliEnrico ScomparinJanet Elizabeth SegerYuko SekiguchiDaiki SekihataMariia SelinaIlya SelyuzhenkovSerhiy SenyukovJin Joo SeoDmitry SerebryakovLaura SerksnyteAdrian SevcencoTebogo Joyce ShabaAlexandre ShabetaiRuben ShahoyanArtem ShangaraevAnjali SharmaBinti SharmaDeependra SharmaHimanshu SharmaMeenakshi SharmaSamarth SharmaSheetal SharmaUpasana SharmaAfnan ShatatOveis SheibaniKenta ShigakiMaya Hachiya ShimomuraJaehyuck ShinSergey ShirinkinQiye ShouYury SibiryakSabyasachi SiddhantaTeodor SiemiarczukTiago Fiorini da SilvaDavid Olle Rickard SilvermyrTawanchat SimantathammakulRadoslav SimeonovBalwan SinghBhawani SinghKamaljeet SinghRanbir SinghRandhir SinghRavindra SinghSweta SinghVivek SinghVikas SinghalTinku Sarkar - SinhaBranislav SitarMario SittaBernhard SkaaliGeorgijs SkorodumovsMaciej SlupeckiNikolai SmirnovRaimond SnellingsEmilie Haugland SolheimJihye SongChristian SonnabendFrancesca SoramelAnalyce Bella Soto-HernandezRik SpijkersIwona Anna SputowskaJoey StaaJohanna StachelIonel StanPatrick John SteffanicStephan Friedrich StiefelmaierDiego StoccoIda StorehaugPeter StratmannSofia StrazziAlessandro SturnioloChristos Pliatskas StylianidisAlexandre Alarcon Do Passo SuaideChristophe Pierre SuireMikhail SukhanovMiljenko SuljicRishat SultanovVikash SumberiaSuharyo SumowidagdoSagarika SwainImrich SzarkaMaciej SzymkowskiSeyed Farid TaghaviGuillaume TaillepiedJun TakahashiGanesh Jagannath TambaveSiyu TangZebo TangDaniel Jesus Tapia TakakiNicolae TapusLucia Anna TarasovicovaMadalina-Gabriela TarzilaGiovanni Francesco TassielliArturo TauroGuillermo Tejeda MunozAdriana TelescaLivia TerlizziCristina TerrevoliSanchari ThakurDeepa ThomasAnatoly TikhonovNicolas TiltmannAnthony Robert TimminsMilan TkacikTomas TkacikAlberica ToiaRyoka TokumotoKeisuke TomohiroNataliya TopilskayaMarco ToppiTheraa M.A TorkPaola Vargas TorresVictor Valencia TorresArianna Grisel Torres RamosAntonio TrifiroAndrea Sofia TrioloSushanta TripathyTulika TripathyStefano TrogoloVictor TrubnikovWladyslaw Henryk TrzaskaTomasz Piotr TrzcinskiAlexandr TumkinRosario TurrisiTrine Spedstad TveterKjetil UllalandBerkin UlukutluAntonio UrasGianluca UsaiMartin ValaNicolo ValleLennart van DoremalenMarco van LeeuwenCasper Arie van VeenRoelof Jan Gijs van WeeldenPierre Vande VyvreDezso VargaZoltan VargaMaria VasileiouAndrey VasilievOton Vazquez DoceOmar Vazquez RuedaVladimir VecherninErmanno VercellinSergio Vergara LimonRahul VermaLucas Anne VermuntRobert VertesiMarta VerweijLinda VickovicZabulon VilakaziOrlando Villalobos BaillieAnna VillaniAlexander VinogradovTiziano VirgiliMaxim Mikael Olavi VirtaVytautas VislaviciusAlexander VodopyanovBenedikt VoelkelMartin Andreas VolklKirill VoloshinSergey VoloshinGiacomo VolpeBarthelemy von HallerIvan VorobyevNikita VozniukJanka VrlakovaJie WanChunzheng WangDongfang WangYuanzhe WangYubiao WangAdam Tadeusz WegrzynekFelix Thomas WeiglhoferSandro Christian WenzelJohannes Peter WesselsSierra Lisa WeyhmillerJens WiechulaJon WikneGrzegorz Andrzej WilkJeremy John WilkinsonGuido Alexander WillemsBernd Stefan WindelbandMichael Andreas WinnJosephina Rae WrightWenya WuYitao WuRan XuAnkur YadavArun Kumar YadavSerpil Yalcin KuzuYorito YamaguchiShiming YangSatoshi YanoZhongbao YinIn Kwon YooJin Hee YoonHyeonjin YuShiming YuanAlperen YuncuValentina ZaccoloChiara ZampolliFederica ZanoneNima ZardoshtiAndrey ZarochentsevPetr ZavadaNikolay ZavyalovMikhail ZhalovBiao ZhangChi ZhangLiuyao ZhangSong ZhangXiaoming ZhangYifei ZhangZhen ZhangMingrui ZhaoVladimir ZherebchevskiiZhi YuDaicui ZhouYou ZhouJianhui ZhuYa ZhuStefan Cristi ZugravelNicola Zurlo
• Organismes : Laboratoire de Physique de Clermont Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de physique subatomique et des technologies associées Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Physique des 2 Infinis de Lyon Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Physique des 2 Infinis de Lyon Institut de Physique des 2 Infinis de Lyon Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de physique subatomique et des technologies associées Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Physique des 2 Infinis de Lyon Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Laboratoire de Physique de Clermont Institut Pluridisciplinaire Hubert Curien Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Institut Pluridisciplinaire Hubert Curien Laboratoire de Physique Subatomique et de Cosmologie Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de physique subatomique et des technologies associées Institut de Physique des 2 Infinis de Lyon Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers

---

Résumé : The first measurements of $\mathrm{K^{*}(892)^{0}}$ resonance production as a function of charged-particle multiplicity in Xe$-$Xe collisions at $\sqrt{s_{\mathrm{NN}}}=$ 5.44 TeV and pp collisions at $\sqrt{s}=$ 5.02 TeV using the ALICE detector are presented. The resonance is reconstructed at midrapidity ($|y|< 0.5$) using the hadronic decay channel $\mathrm{K^{*0}} \rightarrow \mathrm{K^{\pm} \pi^{\mp}}$. Measurements of transverse-momentum integrated yield, mean transverse-momentum, nuclear modification factor of $\mathrm{K^{*0}}$, and yield ratios of resonance to stable hadron ($\mathrm{K^{*0}}$/K) are compared across different collision systems (pp, p$-$Pb, Xe$-$Xe, and Pb$-$Pb) at similar collision energies to investigate how the production of $\mathrm{K^{*0}}$ resonances depends on the size of the system formed in these collisions. The hadronic rescattering effect is found to be independent of the size of colliding systems and mainly driven by the produced charged-particle multiplicity, which is a proxy of the volume of produced matter at the chemical freeze-out. In addition, the production yields of $\mathrm{K^{*0}}$ in Xe$-$Xe collisions are utilized to constrain the dependence of the kinetic freeze-out temperature on the system size using HRG-PCE model.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 07/09/2023
• Auteurs : Amedeo AnselmiAlexandre MansourMarylou ParaNicolas MongardonAlizée PortoJulien GuihaireMarie-Catherine MorgantMatteo PozziBernard CholleyPierre-Emmanuel FalcozPhilippe GaudardGuillaume LebretonFrançois LabasteClaudio BarbantiOlivier FouquetSidney ChocronNicolas MottardMaxime EsvanClaire Fougerou-LeurentErwan FlecherAndré VincentelliNicolas NesselerMarc PierrotGuillaume FlicoteauxPhilippe MauriatAlexandre OuattaraHadrien RozeOlivier HuetMarc-Olivier FischerClaire AlessandriRaphel BellaïcheOphélie ConstantQuentin RouxAndré LyArnaud MeffertJean-Claude MerleLucile PicardElena SkripkinaThierry FolliguetAntonio FioreNicolas D’ostrevyMarie-Catherine MorganPierre-Grégoire GuinotMaxime NguyenLucie Gaide-ChevronnayNicolas TerziGwenhaël ColinOlivier FabreArash AstanehJustin IssardElie FadelDominique FabreAntoine GiraultIolande IonJean Baptiste MenagerDelphine MitilianOlaf MercierFrançois StephanJacques ThesJerôme JouanThibault DuburcqValentin LoobuyckMouhammed MoussaAgnes MugnierNatacha RousseSabrina ManganielloOlivier DesebbeJean-Luc FellahiRoland HenaineMatteo PozziJean-Christophe RichardZakaria RiadChristophe GuervillySami HraiechLaurent PapazianMatthias CastanierCharles ChanavazCyril CadozSebastien GetteGuillaume LouisErick PortocarreroKais BriniNicolas BischoffBruno LevyAntoine KimmounMathieu MatteiPierre PerezAlexandre BourdiolYannick HourmantPierre-Joachim MahéBertrand RozecMickaël Vourc’hStéphane AubertFlorian BazalgetteClaire RogerPierre JaquetBrice Lortat-JacobPierre MordantPatrick NatafJuliette PatrierSophie ProvenchereMorgan RouéRomain SonnevilleAlexy Tran-DinhPaul-Henri WickyCharles Al ZreibiYannis GuyonvarchSophie HamadaAstrid BertierAnatole HarroisJordi MatielloT KerforneCorentin LacroixNicolas BréchotAlain CombesMatthieu SchmidtJuliette ChommelouxJean Michel ConstantinCosimo D’alessandroPierre DemondionAlexandre DemouleMartin DresGuillaume FadelMuriel FartoukhGuillaume HékimianCharles JuvinPascal LeprinceDavid LevyCharles-Edouard LuytMarc Pineton de ChambrunThibaut SchoellPierre FillâtreNicolas MassartRoxane NicolasMaud JonasCharles VidalNicolas AllouSalvatore MuccioDario Di PernaVito-Giovanni RuggieriBruno MourvillierKarl BounaderYoann LauneyThomas LebouvierAlessandro ParasidoFlorian ReizinePhilippe SeguinEmmanuel BesnierDorothée CarpentierThomas ClavierAnne OllandMarion VillardFanny BounesVincent MinvilleAntoine GuillonYannick FedunJames Ross
• Organismes : Laboratoire Traitement du Signal et de l'Image Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre d'Investigation Clinique [Rennes] Laboratoire de Recherche Vasculaire Translationnelle Institut Mondor de Recherche Biomédicale IMRB - PROTECT/"Pharmacologie et Technologies pour les Maladies Cardiovasculaires" [Créteil] Hypertension pulmonaire : physiopathologie et innovation thérapeutique Hypertension pulmonaire : physiopathologie et innovation thérapeutique Research on Healthcare Performance Innovations thérapeutiques en hémostase = Innovative Therapies in Haemostasis Nanomédecine Régénérative Faculté de médecine, maïeutique et sciences de la santé [Strasbourg] Service de Chirurgie Thoracique Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] Centre Hospitalier Régional Universitaire [Montpellier] Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases Pôle Anesthésie Réanimation [CHU de Toulouse] Institut des Maladies Métaboliques et Casdiovasculaires MitoVasc - Physiopathologie Cardiovasculaire et Mitochondriale Centre d'Investigation Clinique [Rennes] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre d'Investigation Clinique [Rennes] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Laboratoire Traitement du Signal et de l'Image Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre d'Investigation Clinique [Rennes] Nutrition, Métabolismes et Cancer Hôpital de la Cavale Blanche - CHRU Brest Optimisation des régulations physiologiques Hypertension pulmonaire : physiopathologie et innovation thérapeutique Hypertension pulmonaire : physiopathologie et innovation thérapeutique Hypertension pulmonaire : physiopathologie et innovation thérapeutique
• Publié dans European Journal of Cardio-Thoracic Surgery le 22/10/2020

---

Résumé : Objectives - The clinical profile and outcomes of patients with Coronavirus Disease 2019 (COVID-19) who require veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or veno-arterial-venous extracorporeal membrane oxygenation (VAV-ECMO) are poorly understood. We aimed to describe the characteristics and outcomes of these patients and to identify predictors of both favourable and unfavourable outcomes. Methods - ECMOSARS is a multicentre, prospective, nationwide French registry enrolling patients who require veno-venous extracorporeal membrane oxygenation (ECMO)/VA-ECMO in the context of COVID-19 infection (652 patients at 41 centres). We focused on 47 patients supported with VA- or VAV-ECMO for refractory cardiogenic shock. Results - The median age was 49. Fourteen percent of patients had a prior diagnosis of heart failure. The most common aetiologies of cardiogenic shock were acute pulmonary embolism (30%), myocarditis (28%) and acute coronary syndrome (4%). Extracorporeal cardiopulmonary resuscitation (E-CPR) occurred in 38%. In-hospital survival was 28% in the whole cohort, and 43% when E-CPR patients were excluded. ECMO cannulation was associated with significant improvements in pH and FiO2 on day 1, but non-survivors showed significantly more severe acidosis and higher FiO2 than survivors at this point (P = 0.030 and P = 0.006). Other factors associated with death were greater age (P = 0.02), higher body mass index (P = 0.03), E-CPR (P = 0.001), non-myocarditis aetiology (P = 0.02), higher serum lactates (P = 0.004), epinephrine (but not noradrenaline) use before initiation of ECMO (P = 0.003), haemorrhagic complications (P = 0.001), greater transfusion requirements (P = 0.001) and more severe Survival after Veno-Arterial ECMO (SAVE) and Sonographic Assessment of Intravascular Fluid Estimate (SAFE) scores (P = 0.01 and P = 0.03). Conclusions - We report the largest focused analysis of VA- and VAV-ECMO recipients in COVID-19. Although relatively rare, the need for temporary mechanical circulatory support in these patients is associated with poor prognosis. However, VA-ECMO remains a viable solution to rescue carefully selected patients. We identified factors associated with poor prognosis and suggest that E-CPR is not a reasonable indication for VA-ECMO in this population.

---

Source