Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 11/11/2023
• Auteurs : Xavier CorveleynCamille CorbelRoxanne FabreRadia ZeghariKathy DujardinPhilippe RobertValeria Manera
• Organismes : Maison des Sciences de l'Homme et de la Société Sud-Est Laboratoire d'Anthropologie et de Psychologie Cliniques, Cognitives et Sociales Laboratoire d'Anthropologie et de Psychologie Cliniques, Cognitives et Sociales Cognition Behaviour Technology Cognition Behaviour Technology Centre de Recherche Jean-Pierre AUBERT Neurosciences et Cancer - U837 Centre Mémoire de Ressources et de Recherche [Nice] Centre Mémoire de Ressources et de Recherche [Nice] Cognition Behaviour Technology
• Publié dans Frontiers in Psychology le 02/11/2020

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Résumé : Objective: Apathy is present in many brain disorders, but it is also prevalent to varying degrees in healthy people. While many tools have been developed to assess levels of apathy in pathology, no standardized measure of apathy in healthy people exists. Method: Therefore, this study aimed to validate the French version of the Apathy Motivation Index (f-AMI). The results of 729 participants were analyzed using an exploratory factorial analysis. Results: Preliminary analyses suggested that the three domains of apathy extracted in the original AMI scale—behavioral activation (BA), social motivation (SM), and emotional sensitivity (ES)—could be found also in the f-AMI. A further exploratory analysis showed that a higher number of factors could be extracted, particularly for women. Specifically, both social and emotional factors could be divided into two sub-factors: (1) social motivation toward strangers or toward an acquaintance and (2) self-directed emotional sensitivity directed toward others. Regarding construct validity, the scores of f-AMI were correlated with the French Dimensional Apathy Scale results. Concerning the divergent validity, emotional sensitivity in apathy is different from depression, anhedonia, and fatigue levels. Conclusion: These results suggest that the f-AMI can be used to assess levels of apathy in healthy adults.

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Fichiers liés : fpsyg-14-1252965.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 09/11/2023
• Auteurs : Shengli TaoWigneron J.-P.Jérôme ChaveZhiyao TangZhiheng WangJiangling ZhuQinghua GuoYi LiuPhilippe Ciais
• Organismes : College of Urban and Environmental Sciences [Beijing] Interactions Sol Plante Atmosphère Evolution et Diversité Biologique Peking University [Beijing] Peking University [Beijing] Peking University [Beijing] Peking University [Beijing] University of New South Wales [Sydney] Laboratoire des Sciences du Climat et de l'Environnement [Gif-sur-Yvette]
• Publié dans Nature Climate Change le 30/10/2020

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Résumé : The resilience of the Amazon rainforest to climate and land-use change is crucial for biodiversity, regional climate and the global carbon cycle. Deforestation and climate change, via increasing dry-season length and drought frequency, may already have pushed the Amazon close to a critical threshold of rainforest dieback. Here, we quantify changes of Amazon resilience by applying established indicators (for example, measuring lag-1 autocorrelation) to remotely sensed vegetation data with a focus on vegetation optical depth (1991-2016). We find that more than three-quarters of the Amazon rainforest has been losing resilience since the early 2000s, consistent with the approach to a critical transition. Resilience is being lost faster in regions with less rainfall and in parts of the rainforest that are closer to human activity. We provide direct empirical evidence that the Amazon rainforest is losing resilience, risking dieback with profound implications for biodiversity, carbon storage and climate change at a global scale.The Amazon rainforest is increasingly under pressure from climate change and deforestation. The resilience of three-quarters of the forest, particularly in drier areas or close to human activity, has been decreasing since the 2000s, indicating that the system may be approaching a tipping point.

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Fichiers liés : s41558-023-01853-8.pdf

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 08/11/2023
• Auteurs : Thomas Rj MoreauVincent BondetJuliette RamosNaïm OuldaliMarie-Alexandra AlyanakianChristine BodemerGlory DinguluCécile DumaineNgoc-Bao DuongJean-Luc CharuelLaurye-Anne EveillardBenjamin FournierMarie-Louise FrémondJean Philippe HerbeuvalArnaud IsapofPierre QuartierCaroline VinitAnne Welfringer-MorinCyril GitiauxIsabelle MelkiDarragh DuffyBrigitte Bader-MeunierMathieu P Rodero
• Organismes : Centre National de la Recherche Scientifique Institut Pasteur [Paris] Institut Pasteur [Paris] Centre National de la Recherche Scientifique Institut Pasteur [Paris] Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques

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Résumé : This study was conducted to identify the contribution of myositis-specific antibodies (MSAs) on the correlation between type I interferon (IFN-I) plasma levels and disease activity in juvenile dermatomyositis (JDM) patients. We prospectively obtained 198 samples from 49 JDM patients. Autoantibody levels were determined for all patients. Muscle activity was scored using Childhood Myositis Assessment Scale (CMAS) and Manual Muscle Testing in 8 muscles (MMT-8) and skin involvement with a Disease Activity Score (DAS). Three homebrew digital ELISA measuring respectively the IFN-α2 subtype, all 12 interferon alpha (IFN-α) subtype proteins (Pan-α), and interferon beta (IFN-β) were used to quantify IFN-I in patient’s plasma. Correlations between IFN-I titers and clinical scores were evaluated using linear mixed-effect models. In our entire cohort, Pan-α and IFN-β were associated with all three clinical scores. Correlations between IFN-β plasma levels and muscle disease activity were stronger than those with IFN-α levels. After stratification on MSAs expression, we found a relatively equal distribution for the most frequent MSAs phenotypes (MDA5+:n=13, NXP2+:n=12, TIF1g+:n=11, No MSAs:n=13). We observed an association between CMAS and IFN-β in all 4 subgroups. In contrast, Pan-α levels were associated with clinical scores only in MDA5+ patients. In this subgroup, IFN-α2 was also strongly associated with muscle scores. These findings underscore the potential role of IFN-β in blood as a reliable biomarker of muscle disease activity in JDM, irrespectively of MSAs positivity. The association of IFN-α subtypes plasma levels with clinical scores only in MDA5+ patients suggests a distinct pathophysiological mechanism in this subgroup.

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Fichiers liés : IFN-b_plasmatic_levels_are_best_predictors_of_musc.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 08/11/2023
• Auteurs : Maryam KhaliliPierre-François BertJean-Pascal GoutoulyArmelle MaraisThierry CandresseMaria-Das-Dores LafargueChristel RenaudPhilippe DarrietGhislaine HilbertPhilippe GallusciPierre PétriacqSabine GuillaumieNathalie OllatJosep Valls FonayetCécile ThibonEric Gomès
• Organismes : Biologie du fruit et pathologie Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Biologie du fruit et pathologie Biologie du fruit et pathologie Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Unité de Recherche Œnologie [Villenave d'Ornon] Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Biologie du fruit et pathologie Plateforme Bordeaux Metabolome Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Unité de Recherche Œnologie [Villenave d'Ornon] Plateforme Bordeaux Metabolome Unité de Recherche Œnologie [Villenave d'Ornon] Plateforme Bordeaux Metabolome Ecophysiologie et Génomique Fonctionnelle de la Vigne

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Résumé : Sémillon is a cultivated grape variety known for contributing to dry and sweet white wine production. However, only seven approved clones have been officially recognized in France[1]. In this study, we aimed to characterize the genetic diversity and metabolomic profiles of a Sémillon clonal population, shedding light on the potential variations within this important grape variety. Through Illumina whole genome sequencing of 53 Sémillon clones, we observed various genetic variations, including single nucleotide polymorphisms (SNPs), providing comprehensive insights into their diversity and genomic variations. Additionally, metabolic profiling of berries was established with a combination of chemical and Gas Chromatography-Mass Spectrometry (GC-MS) analysis, allowing to quantify key quality-related parameters such as pH, acidity, sugar content and volatile thiol precursor compounds. Remarkably, our findings revealed significant variations among Sémillon clones, leading to their placing in three distinct clusters. Moreover, phenotypic evaluations highlighted variations in mid-veraison dates, cluster yield, and berry weight. These findings have practical implications for winemakers and vineyard managers, enabling informed decisions in selecting specific clones with desirable traits to achieve desired wine styles and adapt to specific environments and market demands. To unravel the underlying mechanisms behind the observed metabolomic and phenotypic variation within this Sémillon clonal population, comprehensive investigations of global metabolome profiles, epigenetic variations, and virome of the Sémillon clones will be conducted. Through the implementation of multi-omics approaches, we aim to obtain a comprehensive understanding of the Sémillon clonal population, unraveling complex regulatory networks and identifying factors that drive the unique characteristics of clones. This integrative approach will expand our knowledge beyond individual components and provides valuable insights into the intricate interplay among key players at various biological levels.

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• Type de publi. : Article dans une revue
• Date de publi. : 08/11/2023
• Auteurs : Jean-Philippe ChippauxRodrigue NtoneDavid BenhammouYoann MadecGaëlle NoëlAnais PerilhouFai KarlPierre AmtaMarie SanchezLucrece MatchimPedro ClauteauxLucrèce EtekiMark NdifonYap BoumArmand NkwescheuFabien Taieb
• Organismes : BioTop Institut Pasteur
• Publié dans PLoS Neglected Tropical Diseases le 23/10/2020

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Résumé : Background Snakebites is a serious public health issue but remains a neglected tropical disease. Data on antivenom effectiveness are urgently needed in Africa. We assessed effectiveness of Inoserp PAN-AFRICA (IPA), the recommended antivenom available in Cameroon. Methodology/Principal findings We enrolled 447 patients presenting with snakebite in 14 health facilities across Cameroon. At presentation, cytotoxicity, coagulation troubles and neurotoxicity were graded. We administered two to four vials of antivenom to patients based on hemotoxic or neurotoxic signs. We renewed antivenom administration to patients with persistence of bleedings or neurotoxicity 2 hours after each injection. We defined early improvement as a reduction of the grade of envenomation symptoms 2 hours after first injection. Medium-term effectiveness was investigated looking at disappearance of symptoms during hospitalization. After hospital discharge, a home visit was planned to assess long-term outcomes. Between October 2019 and May 2021, we enrolled 447 (93.7%), including 72% from the savannah regions. The median [IQR] age was 25 [14–40]. Envenomation was diagnosed in 369 (82.6%) participants. The antivenom was administered to 356 patients (96.5%) of whom 256 (71.9%) received one administration. Among these patients, cytotoxic symptoms were observed in 336 (94.4%) participants, coagulation disorders in 234 (65.7%) participants and neurotoxicity in 23 (6.5%) participants. Two hours after the first administration of antivenom, we observed a decrease in coagulation disorders or neurotoxicity in 75.2% and 39.1% of patients, respectively. Complete cessation of bleedings and neurotoxicity occurred in 96% and 93% of patients within 24 hours, respectively. Sequelae have been observed in 9 (3%) patients at the home visit 15 days after hospital admission and 11 (3%) died including one before antivenom injection. Conclusions/Significance We confirmed good effectiveness of the IPA and highlighted the rapid improvement in bleeding or neurotoxicity after the first administration. Sequential administrations of low doses of antivenom, rigorously assessed at short intervals for an eventual renewal, can preserve patient safety and save antivenom. Trial registration NCT03326492 .

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Fichiers liés : main.pdf

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• Type de publi. :
• Date de publi. : 08/11/2023
• Auteurs : Etienne R. PatinAnder del Sol IturraldeUsue Pérez-LopezPierre GastouJean-Pascal TandonnetElisa MargueritPhilippe VivinNathalie OllatMarina de Miguel
• Organismes : Ecophysiologie et Génomique Fonctionnelle de la Vigne Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne] Distributed Systems Group [UPV/EHU] Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne] Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne

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Résumé : Grapevines are grown mainly as grafts worldwide, but the rootstocks most commonly used were selected between the late 19th and early 20th centuries and are based on reduced genetic diversity[1]. In the context of climate change, it is indeed urgent to diversify the range of rootstocks with genotypes much more adapted to drier environments, than the existing ones[2]. The aim of this study was to evaluate the potential of new genetic resources for grapevine rootstock breeding programs. For this purpose, 12 American and Asian wild Vitis species (3 to 5 accessions per species = 50 accessions) were evaluated for their rooting ability and drought response. The plants were submitted to different irrigation treatments (moderate water deprivation vs well-watered) in a phenotyping platform for one month. Evaluation of gas exchange related traits and vegetative growth was performed during the experiment. Rooting ability and root morphology at different developmental stages were also recorded using image analysis using Rhizovision and SmartRoot softwares. We used mixed models to estimate broad-sense heritability. We observed high genetic variation among and within species for root traits and aerial drought response. Genetic correlations between aerial traits in response to drought and constitutive root morphology allowed us to select interesting accessions to be used in breeding programs. The 50 evaluated accessions have been grafted in 2023 to evaluate the interactions with the scion when used as rootstocks. Acknowledgements: This study was supported by funding from INRAE, the Nouvelle-Aquitaine region (project VitiScope) and the CNIV. We acknowledge Maria Lafargue, Cyril Hevin, Nicolas Hocquard and Jean-Pierre Petit for their help with the plant material preparation. References: 1) Riaz, S. et al. (2019) Genetic diversity and parentage analysis of grape rootstocks. Theorethical and Applied Genetics 132, 1847–1860. 2) Marín, D. et al.(2021) Challenges of viticulture adaptation to global change : Tackling the issue from the roots. Australian Journal of Grape and Wine Research, 27(1), Article 1.

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• Type de publi. : Communication dans un congrès
• Date de publi. : 08/11/2023
• Auteurs : Nathalie OllatJean-Pascal TandonnetMarina de MiguelClément Saint CastVirginie LauvergeatJoseph TranBernadette RubioNabil GirolletPierre-François BertMaria-Das-Dores LafarguePhilippe VivinSarah J. CooksonDaniel EsmenjaudElisa Marguerit
• Organismes : Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Interactions Biotiques et Santé Végétale Ecophysiologie et Génomique Fonctionnelle de la Vigne

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Résumé : Rootstocks were the first sustainable and environmentally friendly strategy to cope with a major threat for Vitis vinifera cultivation. In addition to providing Phylloxera resistance, they play an important role in protecting against other soil-borne pests, such as nematodes, and in adapting V. vinifera to limiting abiotic conditions. Today viticulture has to adapt to ongoing climate change whilst simultaneously reducing its environmental impact. In this context, rootstocks are a central element in the development of agro-ecological practices that increase adaptive potential with low external inputs. Despite the apparent diversity of the Vitis genus, only few rootstock varieties are used worldwide and most of them have a very narrow genetic background. This means that there is considerable scope to breed new, improved rootstocks to adapt viticulture for the future. However, in comparison to the extensive research effort devoted to fruit varieties, there is little scientific knowledge to support grapevine rootstock breeding. Since grafting became widespread in viticulture, very few studies have been done on the genetic architecture of the relevant traits in rootstocks, even for resistance to Phylloxera or grafting ability. The current presentation will provide an overview of our knowledge on the genetics of specific rootstock traits, covering resistance to Phylloxera and nematodes, rooting and grafting abilities, and adaptation to drought and salinity. An attempt to list the resources and initiatives at the international level will be made. Acknowledgements: The research for rootstock breeding in Bordeaux has been supported over the years by numerous funding agencies and has benefited from the support of the wine industry. Louis Bordenave, Bernard Douens, Jean-Pierre Petit, Cyril Hévin and Nicolas Hocquard are to be acknowledged for their great involvement in the management of genetic resources and the monitoring of plant material.

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• Type de publi. :
• Date de publi. : 08/11/2023
• Auteurs : Chloé OllivierJérôme DemartyJordi EtchanchuHélène BarralSamuel BitaudPascal BrunetSimon Damien CarrièreJean Philippe ChazarinLéna ColletA. DezetterNesrine FarhaniPierre FischerMaurice GuillodHervé JourdeBehshad KoohborI. MainassaraPierre MarchandMonique OïJean Louis PerrinBrune Raynaud--SchellMarine RousseauCharlie VoisinNanée Chahinian
• Organismes : Hydrosciences Montpellier Centre d'études spatiales de la biosphère Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Milieux Environnementaux, Transferts et Interactions dans les hydrosystèmes et les Sols Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Institut de chimie des milieux et matériaux de Poitiers [UMR 7285] Hydrosciences Montpellier Hydrosciences Montpellier GeoRessources GeoRessources Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier Hydrosciences Montpellier

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Résumé : Bassin versant du Rieu Massel, Sud-Est de la France, piémont Cévenol Les chercheurs d'HSM s'investissent depuis quelques années dans l'étude du fonctionnement du bassin versant du Rieu Massel. Ce cours d'eau intermittent est un affluent du Vidourle. Les débits observés au niveau du barrage de Ceyrac varient de 0 à plus de 200m 3 /s. Cet hydrosystème complexe présente des défis pour les éco-hydrologues, les hydrologues et hydrogéologues de l'UMR. Ce site est également un formidable terrain pédagogique pour les étudiants du master EAU de l'Université de Montpellier.

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Fichiers liés : PrésentationA0_ICOS_nov_2023c-1.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 08/11/2023
• Auteurs : Marina de MiguelEtienne R. PatinElsa ChedidEnrique Saez-LagunaAnder del Sol IturraldeUsue Pérez-LopezJean-Pascal TandonnetPierre-François BertPhilippe VivinElisa MargueritSarah J. CooksonNathalie Ollat
• Organismes : Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Biodiversité, Gènes & Communautés Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne] Distributed Systems Group [UPV/EHU] Universidad del País Vasco [Espainia] / Euskal Herriko Unibertsitatea [España] = University of the Basque Country [Spain] = Université du pays basque [Espagne] Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne

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Résumé : Drought is one of the main challenges for viticulture in the context of global change. The choice of rootstock could be leveraged for vineyard adaptation to drought as we can improve plant performance without modifying the scion variety. However, most of the existing rootstocks, selected over a century ago, have a narrow genetic background which could compromise their adaptive potential. Thus, there is a scope for innovation in grapevine rootstock varieties by exploiting a wider range of wild Vitis species. The aim of this study was to investigate the drought adaptation potential of a wide range of previously unexplored wild Vitis species, integrating information at different biological scales: from genomics, transcriptomics and metabolomics to developmental and functional root traits. Our hypothesis is that metabolites can be considered as intermediate phenotypes in roots because they are expected to be mechanistically related to more complex root phenotypes. For these purposes, we investigated genetic differentiation between species and variability within species using SNPs obtained from Illumina paired-end whole genome sequencing (4k project)[1]. In addition, we characterized the response of cuttings from 12 American, Asian and Eurasian wild Vitis species (50 accessions in total) to moderate drought, during 1 month in a greenhouse experiment, with a focus on root morphological, functional and molecular responses (transcriptomics and metabolomics). We identified variability among species in root osmotic adjustment, an important mechanism of drought tolerance[2]. The link between root osmotic potential and metabolites differentially accumulated in response to drought was analyzed. The results obtained in this work will help to identify new genetic resources to be used in rootstocks breeding programs to improve drought adaptation. In addition, we will provide tools to accelerate the screening of desirable traits in rootstocks using intermediate molecular phenotypes as proxies of complex root responses. Acknowledgements: We received funding from INRAE, University of Bordeaux (project PurVitis), Nouvelle-Aquitaine region (project VitiScope) and CNIV. We acknowledge Maria Lafargue, Cyril Hevin, Nicolas Hocquard and Jean-Pierre Petit for their help with the plant material preparation. 1) Dong, Y.,et al. (2023). Dual domestications and origin of traits in grapevine evolution. Science, 379(6635), 892‑901. 2) Blum, A. (2017). Osmotic adjustment is a prime drought stress adaptive engine in support of plant production. Plant, Cell & Environment, 40(1), 4‑10.

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• Type de publi. :
• Date de publi. : 08/11/2023
• Auteurs : Elsa ChedidPierre GastouJean-Pascal TandonnetPhilippe VivinSarah CooksonPierre-François BertNathalie OllatElisa MargueritMarina De Miguel
• Organismes : Ecophysiologie et Génomique Fonctionnelle de la Vigne Santé et agroécologie du vignoble Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne Ecophysiologie et Génomique Fonctionnelle de la Vigne

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Résumé : In the context of global change, the environmental conditions are expected to be more stressful for viticulture. The choice of the rootstock may play a crucial role to improve the adaptation of viticulture to new biotic and abiotic threats (Ollat et al., 2016). However, the selection of interesting traits in rootstock breeding programs is complex because of the combination of multiple targets in a same ideotype. In this sense, the integration of studies about the genetic architecture for desired biotic and abiotic response traits allow us to identify genomic regions to combine and those with interesting pleiotropic effects. In this work we aimed to study the genetic determinism of several traits related to disease resistance and tolerance to abiotic stresses in Vitis sp. with a potential interest to be used as grapevine rootstocks. For this purpose, 30 genetic maps and QTL mapping data, available in the literature, were collected and combined with unpublished QTL for root traits obtained at EGFV lab. This information was used to construct a dense consensus genetic map of Vitis sp.. Then, a QTL meta-analysis was conducted using the software Biomercator. The obtained consensus genetic map, comprising information from different Vitis sp. is a useful genetic resource for translational genetics. In addition, the identified meta-QTLs, that combined information from independent studies, allowed to reduce QTL confidence intervals, notably for tolerance to abiotic stress traits. These results, highlight the interest of QTL meta-analysis to narrow-down the position of loci controlling desired traits for rootstock breeding programs, as previously proved for scions (Delfino et al., 2019).

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