Philippe JEAN-PIERRE

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• Type de publi. :
• Date de publi. : 05/06/2023
• Auteurs : Maha KooliHenri-Pierre CharlesThaddée BricoutJean-Philippe NoelMaria Ramirez-CorralesBastien Giraud
• Organismes : Laboratoire Fonctions Innovantes pour circuits Mixtes Laboratoire Fonctions Innovantes pour circuits Mixtes Laboratoire Fonctions Innovantes pour circuits Mixtes Laboratoire Fonctions Innovantes pour circuits Mixtes Laboratoire Fonctions Innovantes pour circuits Mixtes Laboratoire Fonctions Innovantes pour circuits Mixtes

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Résumé : Computational SRAM (C-SRAM) is a new computing solution for Near-Memory Computing. It allows to perform operations inside or next to the memory without transferring data over the system bus, leading to significantly reducing energy consuption. Operations are realized on large vectors of data occupying the entire physical row of C-SRAM array, leading to high performance gains. This paper presents the C-SRAM solution as an integrated vector-processing unit to be used by a RISC-V processor as an energy-efficient and high performing co-processor. The proposed programming model of the C-SRAM is based on the system bus of a RISC-V processor.

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Fichiers liés : Kooli82.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 04/06/2023
• Auteurs : Louise TarradeJean-Pierre ChevrotJean-Philippe Magué
• Organismes : Interactions, Corpus, Apprentissages, Représentations LInguistique et DIdactique des Langues Étrangères et Maternelles Institut universitaire de France Institut Rhône-Alpin des systèmes complexes Interactions, Corpus, Apprentissages, Représentations

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Résumé : The study examines the diffusion of lexical innovations (new words) on Twitter between 2012 and 2019, seeking to determine whether the position of users within the social network influences the success or failure of the spread of these innovations. We identify lexical innovations that emerged during 2012-2014 and categorize them into "changes" that become widely adopted versus "buzz" words that fade out after a spike in usage. By comparing the network characteristics of users employing these innovations at each diffusion phase (innovation, propagation, stabilization/decline), the results show that: - The initial users (innovators) have a similar profile regardless of whether the innovation succeeds. -However, during the propagation phase, successful "changes" reach more central, prestigious users, unlike "buzz" words. - An innovation's fate can be predicted as early as the propagation phase based on the network profiles of its users. In conclusion, the position of speakers within the Twitter social network impacts the success of lexical innovation diffusion. Central, influential users are necessary for an innovation to take hold.

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Fichiers liés : proposition_JLC_finale.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 04/06/2023
• Auteurs : Constance DouwesGiovanni BindiAntoine CaillonPhilippe EslingJean-Pierre Briot
• Organismes : Sciences et Technologies de la Musique et du Son Sciences et Technologies de la Musique et du Son Sciences et Technologies de la Musique et du Son Sciences et Technologies de la Musique et du Son Institut de Recherche et Coordination Acoustique/Musique Universidade Federal do Estado do Rio de Janeiro Systèmes Multi-Agents

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Résumé : In most scientific domains, the deep learning community has largely focused on the quality of deep generative models, resulting in highly accurate and successful solutions. However, this race for quality comes at a tremendous computational cost, which incurs vast energy consumption and greenhouse gas emissions. At the heart of this problem are the measures that we use as a scientific community to evaluate our work. In this paper, we suggest relying on a multi-objective measure based on Pareto optimality, which takes into account both the quality of the model and its energy consumption. By applying our measure on the current state-of-the-art in generative audio models, we show that it can drastically change the significance of the results. We believe that this type of metric can be widely used by the community to evaluate their work, while putting computational cost – and in fine energy consumption – in the spotlight of deep learning research.

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Fichiers liés : _ICASSP_23__Is_Quality_Enough__Integrating_Energy_Consumption_in_a_Large_Scale_Evaluation_of_Neural_Audio_Synthesis_Models.pdf

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• Type de publi. : Communication dans un congrès
• Date de publi. : 04/06/2023
• Auteurs : Pierre DevelterJonathan BosseOlivier RabastePhilippe ForsterJean-Philippe Ovarlez
• Organismes : DEMR, ONERA, Université Paris Saclay [Palaiseau] Sondra, CentraleSupélec, Université Paris-Saclay DEMR, ONERA, Université Paris Saclay [Palaiseau] DEMR, ONERA, Université Paris Saclay [Palaiseau] Systèmes et Applications des Technologies de l'Information et de l'Energie DEMR, ONERA, Université Paris Saclay [Palaiseau] Sondra, CentraleSupélec, Université Paris-Saclay

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Résumé : In the state-of-the-art, the Probability of False Alarm (P F A)threshold relationship for the popular Matched Filter (MF) is often derived assuming that unknown non-linear parameters lie on a grid. However, these parameters vary continuously in practice. This is known as the off-grid case. In this article, an asymptotic P F A-threshold relationship for the popular Matched Filter is derived in the off-grid case under complex white Gaussian noise hypothesis using expected Euler characteristics. This asymptotic relationship fits very well with corresponding Monte-Carlo trials in the moderate to low P F A regime.

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Fichiers liés : ICASSP2023.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/06/2023
• Auteurs : Tania MarxLuc-Marie JolyAnne-Laure ParmentierJean-Baptiste PretalliMarc PuyraveauJean-Claude MeuriceJeannot SchmidtOlivier TiffetGilbert FerrettiDominique LauqueDidier HonnartFaraj Al FreijatAlain Eric DubartRomain Genre GrandpierreAlain ViallonDominique PerduPierre Marie RoyToufiq El CadiNathalie BronetGrégory DuncanGilles CardotPhilippe LestavelFrédéric MaunyThibaut Desmettre
• Organismes : Laboratoire de Psychologie Sociale et Cognitive CHU Clermont-Ferrand
• Publié dans American Journal of Respiratory and Critical Care Medicine le 26/10/2020

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Résumé : Rationale: Management of first episodes of primary spontaneous pneumothorax remains the subject of debate. Objectives: To determine whether first-line simple aspiration is noninferior to first-line chest tube drainage for lung expansion in patients with complete primary spontaneous pneumothorax. Methods: We conducted a prospective, open-label, randomized noninferiority trial. Adults aged 18–50 years with complete primary spontaneous pneumothorax (total separation of the lung from the chest wall), recruited at 31 French hospitals from 2009 to 2015, received simple aspiration (n = 200) or chest tube drainage (n = 202) as first-line treatment. The primary outcome was pulmonary expansion 24 hours after the procedure. Secondary outcomes were tolerance of treatment, occurrence of adverse events, and recurrence of pneumothorax within 1 year. Substantial discordance in the numerical inputs used for trial planning and the actual trial rates of the primary outcome resulted in a reevaluation of the trial analysis plan. Measurement and Main Results: Treatment failure occurred in 29% in the aspiration group and 18% in the chest tube drainage group (difference in failure rate, 0.113; 95% confidence interval [CI], 0.026–0.200). The aspiration group experienced less pain overall (mean difference, −1.4; 95% CI, −1.89, −0.91), less pain limiting breathing (frequency difference, −0.18; 95% CI, −0.27, −0.09), and less kinking of the device (frequency difference, −0.05; 95% CI, −0.09, −0.01). Recurrence of pneumothorax was 20% in this group versus 27% in the drainage group (frequency difference, −0.07; 95% CI, −0.16, +0.02). Conclusions: First-line management of complete primary spontaneous pneumothorax with simple aspiration had a higher failure rate than chest tube drainage but was better tolerated with fewer adverse events.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/06/2023
• Auteurs : Charlotte BoussardLaure DelageTania GajardoAlexandre KauskotMaxime BatignesNicolas GoudinMarie-Claude StolzenbergCamille BrunaudPatricia PanikulamQuentin RillerMaryse Moya-NilgesJean SolarzChristelle RepérantBéatrice DurelJean-Claude BordetOlivier PelléCorinne LebretonAude MagérusVithura PirabakaranPablo VargasSébastien DupichaudMarie JeanpierreAngélique VinitMohammed ZarhrateCécile MassonNathalie AladjidiPeter D. ArkwrightBrigitte Bader-MeunierSandrine Baron JolyJoy BenadibaElise BernardDominique BerrebiChristine BodemerMartin CastelleFabienne Charbit-HenrionMarwa ChbihiAgathe DebrayPhilippe DrabentSylvie FraitagMiguel HiéJudith Landmann-ParkerLudovic LhermitteDespina MoshousPierre RohrlichFrank RuemmeleAnne Welfringer-MorinMaud TusseauAlexandre BelotNadine Cerf-BensussanMarie RoelensCapucine PicardBénédicte NevenAlain FischerIsabelle CallebautMickaël MénagerFernando E. SepulvedaFrédéric AdamFrédéric Rieux-Laucat
• Organismes : Imagine - Institut des maladies génétiques (IHU) Imagine - Institut des maladies génétiques (IHU) Cytométrie Pitié-Salpêtrière Unité Mixte de Service Production et Analyse de données en Sciences de la vie et en Santé CHU Trousseau [APHP] Centre d'Immunologie et des Maladies Infectieuses CHU Trousseau [APHP] Institut de minéralogie, de physique des matériaux et de cosmochimie Imagine - Institut des maladies génétiques (IHU)
• Publié dans Blood le 28/10/2020

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Résumé : Dedicator of cytokinesis (DOCK) proteins play a central role in actin cytoskeleton regulation. This is highlighted by the DOCK2 and DOCK8 deficiencies leading to actinopathies and immune deficiencies. DOCK8 and DOCK11 activate CDC42, a RHO-GTPase involved in actin cytoskeleton dynamics, among many cellular functions. The role of DOCK11 in human immune disease has been long suspected but has never been described so far. We studied eight male patients, from seven unrelated families, with hemizygous DOCK11 missense variants leading to reduced DOCK11 expression. The patients were presenting with early-onset autoimmunity, including cytopenia, systemic lupus erythematosus, skin, and digestive manifestations. Patients’ platelets exhibited abnormal ultrastructural morphology and spreading as well as impaired CDC42 activity. In vitro activated T cells and B lymphoblastoid cell lines (B-LCL) of patients exhibited aberrant protrusions and abnormal migration speed in confined channels concomitant with altered actin polymerization during migration. A DOCK11 knock-down recapitulated these abnormal cellular phenotypes in monocytes-derived dendritic cells (MDDC) and primary activated T cells from healthy controls. Lastly, in line with the patients’ autoimmune manifestations, we also observed abnormal regulatory T cells (Tregs) phenotype with profoundly reduced FOXP3 and IKZF2 expression. Moreover, we found a reduced T cell proliferation and an impaired STAT5B phosphorylation upon IL2 stimulation of the patients’ lymphocytes. In conclusion, DOCK11 deficiency is a new X-linked immune-related actinopathy leading to impaired CDC42 activity and STAT5 activation, and associated with abnormal actin cytoskeleton remodeling as well as Tregs phenotype culminating in immune dysregulation and severe early-onset autoimmunity.

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Fichiers liés : BLD-2022-018486R1_Merged_PDF (1).pdf

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• Type de publi. : Chapître d'ouvrage
• Date de publi. : 01/06/2023
• Auteurs : Philippe ZardJean GoldzinkGérard Gengembre
• Organismes : Littérature et poétique comparées

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Fichiers liés : postface de Philippe Zard.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/06/2023
• Auteurs : Jérôme LuxJean David Lau Hiu HoongPierre-Yves MahieuxPhilippe Turcry
• Organismes : Laboratoire des Sciences de l'Ingénieur pour l'Environnement - UMR 7356 Laboratoire des Sciences de l'Ingénieur pour l'Environnement - UMR 7356 Laboratoire des Sciences de l'Ingénieur pour l'Environnement - UMR 7356 Laboratoire des Sciences de l'Ingénieur pour l'Environnement - UMR 7356 La Rochelle Université
• Publié dans Computers in Industry le 30/10/2020

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Fichiers liés : S0166361523000398.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/06/2023
• Auteurs : Grégoire Martin de FrémontNathalie Costedoat-ChalumeauEstibaliz LazaroRakiba BelkhirGaëlle Guettrot-ImbertNathalie MorelGaëtane NocturneAnna MoltoTiphaine GoulenokElisabeth DiotLaurent PerardNicole Ferreira-MaldentMaelle Le BesneraisNicolas LimalNihal MartisNoémie AbisrorOdile Souchaud-DebouverieChristophe RichezVincent SobanskiFrançois MaurierGaëtan SauvetreHervé LevesqueMarie-Agnès TimsitNathalie TieuliéPauline OrquevauxBoris BienvenuMatthieu MahevasThomas PapoCéline Lartigau-RoussinElodie ChauvetEmilie BerthouxFrançoise Sarrot-ReynauldLoïc RaffrayMarion CoudercNicolas Martin SilvaNoémie Jourde-ChicheNicolas BelhommeThierry ThomasVincent PoindronViviane Queyrel-MoranneJuliette DelforgeCamille Le RayEmmanuelle PannierXavier MarietteVéronique Le GuernRaphaèle SerorAlexandra Audemard-VergerEmmanuel AzziBéatrice BannevilleAntoine BaudetConstance Beaudouin BazireCristina BeliznaAlexandre BelotYgal BenhamouAlice BereznéFanny Bernard-GuervillySabine BerthierHoly BezanaharyLisa BialeAdrien BigotClaire Blanchard-DelaunayAnne CalasJulien CampagnePascal CathebrasClaire CazaletsBenjamin ChaigneOlivia ChandesrisJérémy ChatelaisEmmanuel ChatelusFleur CohenBernard CombeCéline ComparonPascal CoquerelleLouise DamianEric DaugasMathilde de MenthonClaire de MoreuilEstelle DelattreAzeddine DellalCatherine Deneux-TharauxAmélie DenisCamille DeprouwEmmanuelle DernisAlban DerouxSandra DesouchesPhilippe DieudéGuillaume DirezMaxime DougadosMarine DriessenAurélie Du-ThanhLaetitia DunogeantCécile DurantCécile-Audrey DurelIsabelle DurieuFlorence EboueElisabeth ElefantOlivier FainBruno FautrelRené-Marc FlipoAline FrazierAntoine FroissartSophie Georgin-LavialleElisabeth GervaisBertrand GodeauFrançois GoffinetAnne GompelLaure GossecPhilippe GoupilleClaire GrangeConstance Guillaud-DanisEric HachullaSabine HoefslootAurélie HummelPatrick JegoStéphanie JobardLaurence Josselin-MahrMarc LambertVincent LangloisDelphine LariviereClaire LarrocheAugustin LatourteChristian LavigneThomas Le GallouGaëlle LerouxJean Guillaume LetarouillyFrédéric LiotéLaurence LoeuilletJonathan LondonValentine LoustauPierre Lozac'HEmmanuel MaheuHélène MaillardHubert MarotteAgathe MasseauArsène MekinianSara Melboucy BelkhirCorinne Miceli-RichardMartin MichaudMarc MichelOlivier MoranneChafika Morati-HafsaouiGuillaume MoulisLuc MouthonBarbara NicolasJacky NizardJérémy OraRodérau OuthElisabeth PasquierJean-Loup PennaforteAntoinette PerlatHélène Petit-BauerEvangeline PilleboutJean-Maxime PiotAgnès PortierOlivier PourratXavier PuechalGregory PugnetManon RedondinAlexis RegentMélanie RorizLaurent SaillerLéa SaveyMarc ScherlingerNicolas SchleinitzJérémie SellamLoïc SentilhesAude ServaisPerrine SmetsChristelle SordetMartin SoubrierKatia Stankovic-StojanovicGeoffrey UrbanskiVéronique VeitEmmanuelle WeberCécile Yelnik
• Organismes : Hôpital Cochin [AP-HP] Centre Hospitalier Universitaire de Bordeaux Hôpital Bicêtre [GHU AP-HP. Université Paris-Saclay, Le Kremlin-Bicêtre] Service de médecine interne et centre de référence des maladies rares [CHU Cochin] Service de Pharmacologie et Immunoanalyse Centre de recherche en Immunologie des Infections virales et des maladies auto-immunes Clinical Epidemiology Applied to Osteoarticular Diseases | Épidémiologie clinique appliquée aux maladies rhumatismales et musculo-squelettiques Assistance publique - Hôpitaux de Paris (AP-HP) Centre Hospitalier Régional Universitaire de Tours Centre hospitalier Saint Joseph - Saint Luc [Lyon] Centre Hospitalier Régional Universitaire de Tours Physiopathologie, Autoimmunité, maladies Neuromusculaires et THErapies Régénératrices Hôpital Henri Mondor CHU Nice [Cimiez] CHU Saint-Antoine [AP-HP] Immunology from Concept and Experiments to Translation = Immunologie Conceptuelle, Expérimentale et Translationnelle Institute for Translational Research in Inflammation - U 1286 Hôpitaux Privés de Metz - Hôpital Robert Schuman -UNEOS Epidémiologie des Maladies Chroniques en zone tropicale CHU Limoges U 1059 – SAINBIOSE Bio-ingénierie
• Publié dans The Lancet Rheumatology le 13/12/2019

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Résumé : Background Adverse pregnancy outcomes in women with primary Sjogren's syndrome have only been evaluated retrospectively using heterogeneous methods and with contradictory results. We aimed to describe adverse pregnancy, delivery, and birth outcome risks in pregnant women with primary Sjogren's syndrome compared with those of a matched general population in France, and to identify factors predictive of disease flares or adverse pregnancy outcomes. Methods We conducted a multicentre, prospective, cohort study in France using the GR2 (Groupe de Recherche sur la Grossesse et les Maladies Rares) registry. Women from the GR2 study were eligible if they had conceived before March, 2021, had primary Sjogren's syndrome according to the American College of Rheumatology and European Alliance of Associations for Rheumatology (EULAR) 2016 classification criteria, and had an ongoing pregnancy at 12 weeks of gestation. In women who entered in the registry with pregnancies before 18 weeks of gestation, we sought to identify factors associated with primary Sjogren's syndrome flare (=3-point increase in EULAR Sjogren's Syndrome Disease Activity Index [ESSDAI] score) or adverse pregnancy outcomes (fetal or neonatal death, placental insufficiency leading to a preterm delivery [<37 weeks of gestation], or small-for-gestational-age birthweight). A matched controlled study compared adverse pregnancy, delivery, and birth outcome rates between pregnant women with primary Sjogren's syndrome from the GR2 registry and matched controls from the general population included in the last French perinatal survey (Enquete Nationale Perinatale 2016). Findings 1944 pregnancies were identified in the GR2 cohort, of which 106 pregnancies in 96 women with primary Sjogren's syndrome were included in this analysis. The median age at pregnancy onset was 33 years (IQR 31-36). 87 (83%) of 105 pregnancies (with ethnicity data) were in White women, 18 (17%) were in Black women; 92 (90%) of 102 had previous systemic activity (ESSDAI score of =1; data missing in four pregnancies), and 48 (45%) of 106 had systemic activity at inclusion. Of 93 pregnancies included at week 18 of gestation or earlier, primary Sjogren's syndrome flares occurred in 12 (13%). No baseline parameters were associated with primary Sjogren's syndrome flare. Four twin pregnancies and one medical termination were excluded from the adverse pregnancy outcome analysis; of the remaining 88, adverse pregnancy outcomes occurred in six (7%). Among pregnancies in women with data for antiphospholipid antibodies (n=55), antiphospholipid antibody positivity was more frequent among pregnancies with adverse outcomes (two [50%] of four pregnancies) compared with those without adverse outcomes (two [ 4%] of 51 pregnancies; p=0 center dot 023). Anti-RNP antibody positivity was also more frequent among pregnancies with adverse outcomes than those without, although this was not statistically significant. In the matched controlled study, adverse pregnancy outcomes occurred in nine (9%) of 105 pregnancies in women with primary Sjogren's syndrome and 28 (7%) of the 420 matched control pregnancies; adverse pregnancy outcomes were not significantly associated with primary Sjogren's syndrome (odds ratio 1 center dot 31, 95% CI 0 center dot 53-2 center dot 98; p=0 center dot 52). Interpretation Pregnancies in women with primary Sjogren's syndrome had very good prognoses for mothers and fetuses, with no overall increase in adverse pregnancy outcome risk compared with the general population. Women with antiphospholipid antibodies or anti-RNP antibodies require close monitoring, because these factors might be associated with a higher risk of adverse pregnancy outcomes. Funding Lupus France, Association des Sclerodermiques de France, Association Gougerot Sjogren, Association Francophone Contre la Polychondrite Chronique Atrophiante, AFM-Telethon, Societe Nationale Francaise de Medecine Interne, Societe Francaise de Rhumatologie, Cochin Hospital, French Health Ministry, Fondation for Research in Rheumatology, Association Prix Veronique Roualet, Union Chimique Belge.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/06/2023
• Auteurs : Renaud LouisTim HarrisonPascal ChanezFrancesco MenzellaGeorge PhilteosBorja CosioNjira LugogoGustavo de LuizAnnie BurdenTimothy AdlingtonNanna KeelingJustin KwiatekEsther Garcia GilWolfgang PohlDaniel DobererJean Benoit MartinotMaud DeschampheleireUlrike HimpeKenneth ChapmanAmarjit CheemaDelbert DorscheidClare RamseyJeffrey RolfBrandie WalkerRonald OlivensteinClaude PoirierPierre LariveeAnne Sofie BjerrumIngrid TitlestadOle HilbergMaritta KilpeläinenPhilippe BonniaudCamille TailléIuliana-Angelica TiotiuPierre-Olivier GirodetFrançois-Xavier BlancJohana PradelliAlain DidierCecilia Nocent EjnainiGaetan DesleeChristophe PisonYoucef DouadiGuillaume MahayGilles DevouassouxBoris MelloniPauline-Marie RouxArnaud BourdinStephanie FryThomas SchaumChristian SchulzDirk SkowaschChristian TaubeTobias WelteWolfgang GleiberRandolf BrehlerJens SchreiberWolfgang SchuetteJuliane KronsbeinReiner BonnetEkkehard BeckDonato LacedoniaGianenrico SennaCristiano CarusoNunzio CrimiFrancesco BlasiPierachille SantusGiorgio Walter CanonicaGabriella GuarnieriGirolamo PelaiaManlio MilaneseClaudio MichelettoAngelo Guido CorsicoNicola ScichiloneGiuseppe SpadaroBas LangeveldJurgen HoltersJan Willem van den BergArthur SmitLennart ConemansHelena van VeenGerald StaaksSverre LehmannJose Maria Echave-SustaetaChristian Domingo RibasGustavo de Luiz MartinezRuperto Gonzalez PerezJuan Luis Garcia RiveroXavier Muñoz GallJose Gregorio Soto CamposPaloma Campo MozoCarmen Vidal PanAna Gomez-Bastero FernandezSergio Campos TellezCarlos Martinez RiveraIrina Diana BoboleaRaquel Morillo GuerreroIsmael Ali GarciaJuan Luis Rodriguez HermosaNikolai StenforsAlf TunsäterDan CuriacChristophe von GarnierJoerg LeuppiPeter Schmid-GrendelmeierShuaib NasserRekha ChaudhuriMonica NordstromDinesh SaralayaPaul PfefferAdel MansurPhilip ShortSally WenzelWilliam Brett CherryHeidi ZafraErika GonzalezWeily SoongBenjamin DavisNeil KaoIftikhar HussainDiego Jose Maselli CaceresJames HarrisWilliam CalhounIleana RodicioDavid KaufmanMark MossEric SztejmanSamuel DeleonKaharu SuminoRavindra KashyapJeffrey LefleinRizan HajalFaisal FakihDavid HillRobert LinMikell JarrattVijay SubramaniamRobert SussmanNayla MumnehJoan ReibmanJared DarveauxRicardo TanTonny TanusVinay SikandGailen MarshallHemalini MehtaJeremy ColeBrad GoodmanDeborah GossJose BardelasAaron MilstoneVinay MehtaLee CloreMark MillardMichael PalumboDileep PuppalaMila LeongBruce PrennerEmory RobinetteHengameh Heidarian RaissyDavid FostWarren PleskowMichael MarcusJonathan IlowiteWendy MooreGary StevenLuis de la CruzGeoffrey ChuppWilliam BergerChristopher RandolphFernando HolguinShahrukh KureishyEdward CampbellRudi PecheLaura PiniAlberto PapiBianca BeghéSilvia PeveriAythamy Henriquez SantaJacinto Ramos GonzalezInes VingeRoy St. John
• Organismes : Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research
• Publié dans Journal of Allergy and Clinical Immunology: In Practice le 27/10/2020

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Résumé : The phase IIIb, randomized, parallel-group, placebo-controlled ANDHI double-blind (DB) study extended understanding of the efficacy of benralizumab for patients with severe eosinophilic asthma. Patients from ANDHI DB could join the 56-week ANDHI in Practice (IP) single-arm, open-label extension substudy.

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Fichiers liés : ANDHI+IN+PRACTICE+MARZO+2023.pdf

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