Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Amaury MartinPierre-Philippe GrandMatthew HullJean RoussetLars Oberbeck
• Organismes : Institut Photovoltaïque d’Ile-de-France (ITE) Institut Photovoltaïque d’Ile-de-France (ITE) EDF R&D Institut Photovoltaïque d’Ile-de-France (ITE) TotalEnergies OneTech [France] Institut Photovoltaïque d’Ile-de-France (ITE) EDF R&D Institut Photovoltaïque d’Ile-de-France (ITE) TotalEnergies OneTech [France]
• Publié dans EPJ Photovoltaics le 02/11/2020

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Résumé : Perovskite on silicon tandem technologies offer a promising way to overcome the efficiency limit of single-junction crystalline silicon modules and are therefore widely studied. Besides the cost reduction potential of using tandem modules in utility-scale PV plants, the application of bifacial PV modules offers additional opportunities to reduce costs by increasing the energy yield. However, the bifaciality factor of tandem PV modules using bifacial crystalline silicon solar cells is typically lower than that of single-junction bifacial modules, considering the asymmetric architecture of the module with higher front-side than rear-side efficiency. In this study, we assess a symmetrical bifacial triple-junction perovskite/silicon/perovskite PV module architecture which allows for a significant improvement of the PV module rear side efficiency. Cost of ownership, energy yield and levelized cost of energy modeling show the superior performance of such modules compared to crystalline silicon and perovskite/silicon tandem modules specifically in vertical mounting applications that are used e.g.in AgriPV or noise protection PV walls on highways.

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Fichiers liés : pv230035.pdf

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Source

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Philippe MerleJean-Frédéric BlancJulien EdelineKarine Le MalicotManon AllaireEric AssenatMeriem GuarssifiMohamed BouattourJean-Marie PéronPierre Laurent-PuigMassimo LevreroCharlotte CostentinBoris GuiuHarry SokolDavid TougeronThomas AparicioJean-Charles NaultJean-Marc Phélip
• Organismes : Centre de Recherche en Cancérologie de Lyon Centre Hospitalier Universitaire de Bordeaux Oncogenesis, Stress, Signaling Lipides - Nutrition - Cancer [Dijon - U1231] CHU Pitié-Salpêtrière [AP-HP] Lipides - Nutrition - Cancer [Dijon - U1231] UFR Sciences Fondamentales et Biomédicales [Sciences] - Université Paris Cité Centre de Recherche en Cancérologie de Lyon Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) CHU Montpellier = Montpellier University Hospital Institut Desbrest d'Epidémiologie et de Santé Publique Centre de Recherche Saint-Antoine FHU Paris Center for Microbiome Medicine Centre hospitalier universitaire de Poitiers = Poitiers University Hospital AP-HP. Université Paris Saclay Centre de Recherche des Cordeliers Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne]
• Publié dans Digestive and Liver Disease le 01/11/2020

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Résumé : A substantial proportion of patients with hepatocellular carcinoma have to face up, sooner or later, to systemic therapy. The current standards as first line systemic therapies are either atezolizumab (anti-PD-L1) plus bevacizumab (anti-VEGF), or durvalumab (anti-PD-L1) plus tremelimumab (anti-CTLA-4). However, the median overall survival remains below 20 months, and a minority of patients become long-term survivors. Of interest in immune-oncology strategies for hepatocellular carcinoma, the objective response seems to be the most reliable surrogate marker of better overall survival. TRIPLET-HCC (NCT05665348) is a multicentre, randomised, open-label phase II-III trial designed to evaluate efficacy and safety of the triple combination by the addition of ipilimumab (anti-CTLA-4) to atezolizumab/bevacizumab, versus the double atezolizumab/bevacizumab combination. The main inclusion criteria are histologically proven BCLC-B/C HCC without previous systemic therapy. The primary objective of the phase II is the objective response rate in the triple arm, and OS in the triple versus double arms in the phase III. Secondary endpoints common to the phases II and III are the comparisons of progression-free survival, objective response rates, tolerance and quality of life. In addition, genetic and epigenetic studies from tissue and circulating DNA/RNA will be conducted to assess their prognostic or predictive value.

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Fichiers liés : S1590865823001913.pdf

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Source

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : G. 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AmblerChristoph AmelungMaximilian AmerlChristoph AmesDante AmideiSusana Patricia Amor dos SantosSimone AmorosoKieran Robert AmosViktor AnanievChristos AnastopoulosTimothy Robert AndeenJohn Kenneth AndersStefio Yosse AndreanAttilio AndreazzaStylianos AngelidakisAaron AngeramiAlexey AnisenkovAlberto AnnoviClaire AntelMatthew Thomas AnthonyEgor AntipovMario AntonelliDaniel Joseph AntrimFabio AnulliMasato AokiTakumi AokiJavier Alberto Aparisi PozoMarco AparoLudovica Aperio BellaChristian AppeltNordin Aranzabal BarrioVictor Araujo FerrazChiara ArcangelettiAyana Tamu ArceEloisa ArenaJean-Francois ArguinSpyros ArgyropoulosJan-Hendrik ArlingAaron James ArmbrusterOlivier ArnaezHannah ArnoldZulit Paola Arrubarrena TameGiacomo ArtoniHaruka AsadaKanae AsaiShoji AsaiNedaa Alexandra AsbahJihad AssahsahKetevi Adikle AssamaganRobert AstalosRyan Justin AtkinMarkus Julian AtkinsonNaim Bora AtlayHicham AtmaniPrachi AtmasiddhaKamil AugstenSilvia AuricchioAdrien AuriolVolker Andreas AustrupGal 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• Organismes : Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules AstroParticule et Cosmologie AstroParticule et Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont AstroParticule et Cosmologie Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois 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2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules AstroParticule et Cosmologie Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers AstroParticule et Cosmologie Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie AstroParticule et Cosmologie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie AstroParticule et Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie
• Publié dans Phys.Rev.D le 05/03/2026

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Résumé : A search is presented for a heavy resonance $Y$ decaying into a Standard Model Higgs boson $H$ and a new particle $X$ in a fully hadronic final state. The full Large Hadron Collider Run 2 dataset of proton-proton collisions at $\sqrt{s}= 13$ TeV collected by the ATLAS detector from 2015 to 2018 is used, and corresponds to an integrated luminosity of 139 fb$^{-1}$. The search targets the high $Y$-mass region, where the $H$ and $X$ have a significant Lorentz boost in the laboratory frame. A novel signal region is implemented using anomaly detection, where events are selected solely because of their incompatibility with a learned background-only model. It is defined using a jet-level tagger for signal-model-independent selection of the boosted $X$ particle, representing the first application of fully unsupervised machine learning to an ATLAS analysis. Two additional signal regions are implemented to target a benchmark $X$ decay into two quarks, covering topologies where the $X$ is reconstructed as either a single large-radius jet or two small-radius jets. The analysis selects Higgs boson decays into $b\bar{b}$, and a dedicated neural-network-based tagger provides sensitivity to the boosted heavy-flavor topology. No significant excess of data over the expected background is observed, and the results are presented as upper limits on the production cross section $\sigma(pp \rightarrow Y \rightarrow XH \rightarrow q\bar{q}b\bar{b}$) for signals with $m_Y$ between 1.5 and 6 TeV and $m_X$ between 65 and 3000 GeV.

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