Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Mikhaël GiabicaniLaure ArdittyMarie France MamzerIsabelle FournelFiona B. EcarnotNicolas Meunier-BeillardFabrice BruneelEmmanuel WeissMarta SpranziJean Philippe RigaudJean Pierre Quenot
• Organismes : Université de Versailles Saint-Quentin-en-Yvelines
• Publié dans PLoS ONE le 25/10/2020

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Résumé : Introduction Conflicts between relatives and physicians may arise when decisions are being made about limiting life-sustaining therapies (LST). The aim of this study was to describe the motives for, and management of team-family conflicts surrounding LST limitation decisions in French adult ICUs. Methods Between June and October 2021, French ICU physicians were invited to answer a questionnaire. The development of the questionnaire followed a validated methodology with the collaboration of consultants in clinical ethics, a sociologist, a statistician and ICU clinicians. Results Among 186 physicians contacted, 160 (86%) answered all the questions. Conflicts over LST limitation decisions were mainly related to requests by relatives to continue treatments considered to be unreasonably obstinate by ICU physicians. The absence of advance directives, a lack of communication, a multitude of relatives, and religious or cultural issues were frequently mentioned as factors contributing to conflicts. Iterative interviews with relatives and proposal of psychological support were the most widely used tools in attempting to resolve conflict, while the intervention of a palliative care team, a local ethics resource or the hospital mediator were rarely solicited. In most cases, the decision was suspended at least temporarily. Possible consequences include stress and psychological exhaustion among caregivers. Improving communication and anticipation by knowing the patient's wishes would help avoid these conflicts. Conclusion Team-family conflicts during LST limitation decisions are mainly related to requests from relatives to continue treatments deemed unreasonable by physicians. Reflection on the role of relatives in the decision-making process seems essential for the future.

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Fichiers liés : journal.pone.0284756.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Souleymane TassembedoMwiya MwiyaAnais MennecierChipepo KankasaPaulin FaoJean-Pierre MolèsDramane KaniaCatherine Chunda-LiyokaLeticia Delphine SakanaMorgana d'OttaviAjani Ousmane TaofikiDavid RutagweraM M Wilfried-TongaNicolas NagotPhilippe Van De Perre
• Organismes : Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections
• Publié dans AIDS. Official journal of the international AIDS Society le 23/08/2019

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Résumé : Objective: Our study aimed to assess the PMTCT indicators in Burkina Faso and Zambia using a patient-orientated innovative strategy based on the second visit in the Expanded Program on Immunization (EPI-2) visit at 6-8 weeks. Design: This was a cross sectional study. Methods: We assessed women attending EPI-2 at primary healthcare facilities in Burkina Faso and Zambia with their children about their exposure to PMTCT interventions. For women living with HIV (WLHIV), viral load was measured and their children were tested for HIV DNA using point of care devices. Results: Overall, 25 093 were enrolled from Burkina Faso and 8961 women from Zambia. Almost, all women attended at least one antenatal care visit. Among those aware of their HIV-positive status, 95.8 and 99.2% were on antiretroviral therapy (ART) in Burkina Faso and Zambia, respectively. Among WLHIV on ART, 75 and 79.2% achieved a viral load suppression (viral load <1000 copies/ml) in Burkina Faso and Zambia, respectively. Infant postnatal prophylaxis was administered from birth until EPI-2 to 60.9 and 89.7% of HIV-exposed children in Burkina Faso and Zambia, respectively. In Burkina Faso, only 60 of 192 (31.3%) of HIV-exposed children were sampled at day 42 for early infant diagnosis (EID) and 3 (1.6%) received a result by EPI-2. In Zambia, these figures were 879 of 1465 (64.0%) and 9.9% (145/1465), respectively for HIV-exposed children sampled at birth. Conclusion: This evaluation strategy at EPI-2 visit could strengthen program monitoring and help identifying gaps to be addressed on the last mile towards elimination of MTCT of HIV.

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Fichiers liés : AIDS-D-23-00419.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Jean-Baptiste ChansonAleksandra Nadaj-PaklezaAnne-Laure Bedat-MilletAriane ChoumertAnne BarnierGhassen HamdiGaëtan LescaFabienne PrieurArnaud BruneelPhilippe LatourTanya StojkovicShahram AttarianNathalie Bonello‐palotNicolas PonsGorka Fernandez-EulateAntoine PegatMarie TheaudinRegis GuieuPaolo RipellinoManon DevedjianPatrick MaceMarion MasingueSarah Leonard-LouisPhilipe PetiotPauline RocheEmilien BernardFrancoise BouhourJean-Marc GoodAnnie VerschuerenAude-Marie GrapperonEmmanuelle SalortAnais Grosset
• Organismes : Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques Centre Hospitalier Universitaire d'Angers Hôpitaux Universitaires de Strasbourg Observatoire National Français des patients atteints de DMFSH Observatoire National Français des patients atteints de DMFSH جامعة سوسة = Université de Sousse = University of Sousse Hospices Civils de Lyon Centre Hospitalier Universitaire de Saint-Etienne [CHU Saint-Etienne] AP-HP - Hôpital Bichat - Claude Bernard [Paris] Groupement Hospitalier Lyon-Est CHU Pitié-Salpêtrière [AP-HP] Centre de recherche en Myologie – U974 SU-INSERM Hôpital de la Timone [CHU - APHM] Marseille medical genetics - Centre de génétique médicale de Marseille Hôpital de la Timone [CHU - APHM] MetaGenoPolis Université Paris-Saclay CHU Pitié-Salpêtrière [AP-HP] Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL] Université de Lausanne = University of Lausanne Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research Département de Biochimie [Hôpital de la Timone - APHM] Hôpital de la Timone [CHU - APHM] CHU Pitié-Salpêtrière [AP-HP] Centre de recherche en Myologie – U974 SU-INSERM CHU Pitié-Salpêtrière [AP-HP] Hôpital de la Conception [CHU - APHM] Hôpital neurologique et neurochirurgical Pierre Wertheimer [CHU - HCL] Hospices Civils de Lyon Centre Hospitalier Universitaire Vaudois = Lausanne University Hospital [Lausanne] Centre de résonance magnétique biologique et médicale Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - APHM] Hôpital de la Timone [CHU - APHM] Centre de résonance magnétique biologique et médicale Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - APHM] Hôpital de la Timone [CHU - APHM] Université de Lorraine
• Publié dans European Journal of Neurology le 22/10/2020

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Julia MaruaniFanny MolièreOphélia GodinAntoine YrondiDjamila BennabiRaphaelle RichieriWissam El-HageEtienne AllauzeLoic AnguillAlexandra BouvardVincent CamusJean-Michel DoreyB EtainGuillaume FondJean-Baptiste GentyEmmanuel HaffenJérôme HoltzmannMathilde HornFrançois KazourAnne-Sophie NguonJean PetrucciRomain ReyFlorian StephanGuillaume VaivaMichel WalterMichel LejoyeuxMarion LeboyerPierre-Michel LlorcaPhilippe CourtetBruno AouizeratePierre-Alexis Geoffroy
• Organismes : Fondation FondaMental [Créteil] GHU AP-HP Nord - Université Paris Cité AP-HP - Hôpital Bichat - Claude Bernard [Paris] Maladies neurodéveloppementales et neurovasculaires Fondation FondaMental [Créteil] Neuropsychiatrie : recherche épidémiologique et clinique CHU Montpellier = Montpellier University Hospital Fondation FondaMental [Créteil] IMRB - "Neuropsychiatrie translationnelle" [Créteil] Fondation FondaMental [Créteil] Centre Hospitalier Universitaire de Toulouse Toulouse NeuroImaging Center Fondation FondaMental [Créteil] Centre d'Investigation Clinique de Besançon Laboratoire de Neurosciences Intégratives et Cliniques - UFC (UR 481) Fondation FondaMental [Créteil] Institut FRESNEL Imagerie MOléculaire pour applications THéranostiques personnalisées Imaging, Brain & Neuropsychiatry Fondation FondaMental [Créteil] Fondation FondaMental [Créteil] Institut Pascal Fondation FondaMental [Créteil] Toulouse NeuroImaging Center Centre Hospitalier Universitaire de Toulouse Fondation FondaMental [Créteil] Nutrition et Neurobiologie intégrée Centre hospitalier Charles Perrens [Bordeaux] Fondation FondaMental [Créteil] Imaging, Brain & Neuropsychiatry Fondation FondaMental [Créteil] Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Centre Hospitalier le Vinatier [Bron] Optimisation thérapeutique en Neuropsychopharmacologie Fondation FondaMental [Créteil] Fondation FondaMental [Créteil] Centre d'études et de recherche sur les services de santé et la qualité de vie Fondation FondaMental [Créteil] Fédération Hospitalo-Universitaire de Médecine de Précision en Psychiatrie = Addiction And Psychiatry Transformation with Precision Medicine [Créteil, France] CHU Henri Mondor [Créteil] Institut Mondor de Recherche Biomédicale Fondation FondaMental [Créteil] Centre d'Investigation Clinique de Besançon Laboratoire de Neurosciences Intégratives et Cliniques - UFC (UR 481) Fondation FondaMental [Créteil] [GIN] Grenoble Institut des Neurosciences Pôle Psychiatrie et Neurologie [Grenoble] Fondation FondaMental [Créteil] Hôpital Fontan (CHRU Lille) Fondation FondaMental [Créteil] Imaging, Brain & Neuropsychiatry Fondation FondaMental [Créteil] [GIN] Grenoble Institut des Neurosciences Pôle Psychiatrie et Neurologie [Grenoble] Fondation FondaMental [Créteil] CHU Henri Mondor [Créteil] Institut Mondor de Recherche Biomédicale Fédération Hospitalo-Universitaire de Médecine de Précision en Psychiatrie = Addiction And Psychiatry Transformation with Precision Medicine [Créteil, France] Fondation FondaMental [Créteil] Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Centre Hospitalier le Vinatier [Bron] Fondation FondaMental [Créteil] Soins Primaires, Santé Publique, Registre des cancers de Bretagne Occidentale Hopital de Bohars - CHRU Brest Fondation FondaMental [Créteil] Hôpital Fontan (CHRU Lille) Centre National de Ressources et de Résilience [Lille] Fondation FondaMental [Créteil] Soins Primaires, Santé Publique, Registre des cancers de Bretagne Occidentale Hopital de Bohars - CHRU Brest Fondation FondaMental [Créteil] AP-HP - Hôpital Bichat - Claude Bernard [Paris] Maladies neurodéveloppementales et neurovasculaires Groupe hospitalier universitaire Paris psychiatrie & neurosciences [Paris] Fondation FondaMental [Créteil] CHU Henri Mondor [Créteil] Institut Mondor de Recherche Biomédicale Fédération Hospitalo-Universitaire de Médecine de Précision en Psychiatrie = Addiction And Psychiatry Transformation with Precision Medicine [Créteil, France] Fondation FondaMental [Créteil] Institut Pascal Fondation FondaMental [Créteil] Neuropsychiatrie : recherche épidémiologique et clinique Fondation FondaMental [Créteil] Nutrition et Neurobiologie intégrée Centre hospitalier Charles Perrens [Bordeaux] Fondation FondaMental [Créteil] AP-HP - Hôpital Bichat - Claude Bernard [Paris] Maladies neurodéveloppementales et neurovasculaires Institut des Neurosciences Cellulaires et Intégratives Groupe hospitalier universitaire Paris psychiatrie & neurosciences [Paris]
• Publié dans Journal of Affective Disorders le 31/10/2020

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Résumé : Patients suffering from treatment-resistant depression (TRD) are at risk of suicide. Sleep and circadian rhythm alterations are widely recognized as core symptoms of major depressive disorder and are associated with suicidal ideation. Thus, sleep and circadian rhythm alterations may be targeted to prevent suicide.

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Fichiers liés : 1-s2.0-S0165032723002719-main.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Chloé LaurencinNoémie TimestitAna MarquesDomitille Dilly DuchezCaroline GiordanaSara MeoniMarine HuddlestoneTeodor DanailaMathieu AnheimHélène KlingerTiphaine VidalMarion FatissonCatherine CaireMikaïl NourredinePhilippe BoulinguezCarole DhelensBénédicte BallangerStéphane PrangeSylvie BinStéphane Thobois
• Organismes : Service d'Electroneuromyographie et Service de Neurologie C [Hôpital Pierre Wertheimer - HCL] Service de neuro-oncologie [Hôpital Pierre Wertheimer - HCL] Service d'Electroneuromyographie et Service de Neurologie C [Hôpital Pierre Wertheimer - HCL] Fédération de Médecine Translationnelle de Strasbourg Institut de Génétique et de Biologie Moléculaire et Cellulaire Service d'Electroneuromyographie et Service de Neurologie C [Hôpital Pierre Wertheimer - HCL] Service d'Electroneuromyographie et Service de Neurologie C [Hôpital Pierre Wertheimer - HCL] Service d'Electroneuromyographie et Service de Neurologie C [Hôpital Pierre Wertheimer - HCL] Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Hôpital Edouard Herriot [CHU - HCL] Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Service d'Electroneuromyographie et Service de Neurologie C [Hôpital Pierre Wertheimer - HCL] Institut des sciences cognitives Marc Jeannerod - Centre de neuroscience cognitive - UMR5229 Service d'Electroneuromyographie et Service de Neurologie C [Hôpital Pierre Wertheimer - HCL] Institut des sciences cognitives Marc Jeannerod - Centre de neuroscience cognitive - UMR5229
• Publié dans Journal of Neurology le 01/11/2020

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Résumé : Background Impulse control disorders (ICDs) are frequently encountered in Parkinson's disease (PD). Objectives We aimed to assess whether clonidine, an α2-adrenergic receptor agonist, would improve ICDs. Methods We conducted a multicentre trial in five movement disorder departments. Patients with PD and ICDs (n = 41) were enrolled in an 8-week, randomised (1:1), double-blind, placebo-controlled study of clonidine (75 μg twice a day). Randomisation and allocation to the trial group were carried out by a central computer system. The primary outcome was the change at 8 weeks in symptom severity using the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease-Rating Scale (QUIP-RS) score. A reduction of the most elevated subscore of the QUIP-RS of more than 3 points without any increase in the other QUIP-RS dimension defined success. Results Between 15 May 2019 and 10 September 2021, 19 patients in the clonidine group and 20 patients in the placebo group were enrolled. The proportion difference of success in reducing QUIP-RS at 8 weeks, was 7% (one-sided upper 90% CI 27%) with 42.1% of success in the clonidine group and 35.0% in the placebo group. Compared to patients in the placebo group, patients in the clonidine group experienced a greater reduction in the total QUIP-RS score at 8 weeks (11.0 points vs. 3.6). Discussion Clonidine was well tolerated but our study was not enough powerful to demonstrate significant superiority compared to placebo in reducing ICDs despite a greater reduction of total QUIP score at 8 weeks. A phase 3 study should be conducted. Trial Registration The study was registered (NCT03552068) on clinicaltrials.gov on June 11, 2018.

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Fichiers liés : Laurencin et al. - 2023 - Efficacy and safety of clonidine for the treatment.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Armen TumasyanWolfgang AdamJanik Walter AndrejkovicThomas BergauerSuman ChatterjeeKonstantinos DamanakisMarko DragicevicAlberto Escalante del VallePriya Sajid HussainManfred JeitlerNatascha KrammerLukas LechnerDietrich LikoIvan MikulecPeter PaulitschFlorian Michael PittersJochen SchieckRobert SchöfbeckDennis SchwarzSebastian TemplWolfgang WaltenbergerClaudia-Elisabeth WulzMohamed Rashad DarwishTahys JanssenTomas KelloHaifa Rejeb SfarPierre van MechelenEmil Sørensen BolsJorgen d'HondtAlexandre de MoorMartin DelcourtHesham El FahamSteven LowetteSeth MoortgatAlexander MortonDenise MüllerAbanti Ranadhir SahasransuStefaan TavernierWalter van DoninckDavid VanneromBarbara ClerbauxGilles de LentdeckerLaurent FavartDmytro HohovJohny JaramilloK LeeMostafa MahdavikhorramiInna MakarenkoAndrea MalaraSantiago ParedesLaurent PétréNicolas PostiauLaurent ThomasMax Vanden BemdenCatherine Vander VeldePascal VanlaerDidar DoburJoscha KnolleLuka LambrechtGianny MestdachMarek NiedzielaCésar RendónChristos RoskasAmrutha SamalanKirill SkovpenMichael TytgatNiels van den BosscheBasile VermassenLiam WezenbeekAnna BeneckeGiacomo BrunoFlorian Joel J BuryClaudio CaputoPieter DavidChristophe DelaereIzzeddin Suat DonertasAndrea GiammancoKhawla JaffelSandhya JainSa JainVincent LemaitreKuntal MondalAngela TaliercioTu Thong TranPietro VischiaSébastien WertzGilvan AlvesEduardo CoelhoCarsten HenselArthur MoraesPatricia Rebello TelesWalter Luiz Aldá JúniorMiguel Alves Gallo PereiraMapse Barroso Ferreira FilhoHelena Brandao MalbouissonWagner CarvalhoJose ChinellatoEliza Melo da CostaGustavo Gil da SilveiraDilson de Jesus DamiaoVitor dos Santos SousaSandro Fonseca de SouzaJordan MartinsClemencia Mora HerreraKevin Mota AmariloLuiz MundimHelio NogimaAlberto SantoroSheila Mara Silva Do AmaralAndre SznajderMauricio ThielFelipe Torres da Silva de AraujoAntonio Vilela PereiraCesar Augusto BernardesLuigi CalligarisT.R Fernandez Perez TomeiEduardo de Moraes GregoresPedro G MercadanteSergio F NovaesSandra S PadulaAleksandar AleksandrovGeorgy AntchevRoumyana HadjiiskaPlamen IaydjievMilena MishevaMircho RodozovMariana ShopovaGeorgi SultanovAnton DimitrovTodor IvanovLeander LitovBorislav PavlovPeicho PetkovAnton PetrovElton ShumkaShalini ThakurTongguang ChengTahir JavaidMonika MittalL YuanMuhammad AhmadGerry BauerZhen HuSamet LezkiKai YiGuo-Ming ChenHe-Sheng ChenMingshui ChenFabio IemmiChun-Hua JiangAnshul KapoorHanjun KouHongbo LiaoZhenan LiuVukasin MilosevicFabio MontiRamkrishna SharmaJunquan TaoJoshuha Thomas-WilskerJ WangHuaqiao ZhangJingzhou ZhaoAntonis AgapitosYing AnYong BanCheng ChenAndrew LevinCongqiao LiQiang LiXudong LyuYajun MaoSi-Jin QianXiaohu SunDayong WangJie XiaoHeng YangMeng LuZhengyun YouXuyang GaoDuncan LeggatHideki OkawaY ZhangZhen LinChenfeng LuMeng XiaoCarlos AvilaDiego Andres Barbosa TrujilloAndrés CabreraCarlos FlorezJorge FragaJhovanny Mejia GuisaoFelipe RamirezManuel RodriguezJosé David Ruiz AlvarezDuje GiljanovicNikola GodinovicDamir LelasIvica PuljakZeljko AntunovicMarko KovacToni SculacVuko BrigljevicBhakti Kanulal ChitrodaDinko FerencekDevdatta MajumderSaswat MishraMatej RoguljicAndrei StarodumovTatjana SusaAlexandros AttikisKonstantinos ChristoforouMarina KolosovaSotiroulla KonstantinouJehad MousaCharalambos NicolaouFotios PtochosPanos A RazisHans RykaczewskiHalil SakaAnton StepennovM FingerM FingerAntonin KvetonEdy AyalaEdgar Carrera JarrinHassan AbdallaYasser AssranMohammed MahmoudYasser MohammedSandeep BhowmikRam Krishna DewanjeeKarl EhatahtMario KadastikTorben LangeSaswati NandanChristine NielsenJoosep PataMartti RaidalLaurits TaniChristian VeelkenPaula EerolaHenning KirschenmannKenneth OsterbergMikko VoutilainenShudhashil BharthuarErik BrückenFrancisco Ignacio Garcia FuentesJoona HavukainenM.S KimRitva KinnunenTapio LampénKati Lassila-PeriniSami LehtiTomas LindénMikko LottiLaura MartikainenMikael MyllymäkiJennifer OttMilla-Maarit RantanenHannu SiikonenEija TuominenJorma TuominiemiPanja-Riina LuukkaHenri PetrowTuure TuuvaChiara AmendolaMarc BesanconFabrice CoudercMarc DejardinDaniel DenegriJean-Louis FaureFederico FerriSerguei GanjourPhilippe GrasGautier Hamel de MonchenaultPatrick JarryVictor LohezicJulie MalclesJohn RanderAndré RosowskyMehmet Özgür SahinAurore Savoy-NavarroPolina SimkinaMaksym TitovCristian Baldenegro BarreraFlorian BeaudetteAxel Buchot PerraguinPhilippe BussonAlessandra CappatiClaude CharlotFlorian DamasOlivier DavignonBatoul DiabGuillaume FalmagneBruno Afonso Fontana Santos AlvesS GhoshRaphael Granier de CassagnacAlexandre HakimiBharadwaj HarikrishnanGeliang LiuJona MottaMatthew NguyenChristophe OchandoLouis PortalesRoberto SalernoUttiya SarkarJean-Baptiste SauvanYves SiroisAlessandro TarabiniElena VernazzaAlexandre ZabiAmina ZghicheJean-Laurent AgramJeremy AndreaDylan ApparuDaniel BlochGuillaume BourgatteJean-Marie BromEric Christian ChabertCaroline CollardDouja DarejUlrich GoerlachClément GrimaultAnne-Catherine Le BihanPierre van HoveStephanie BeauceronBenjamin BlanconGaelle BoudoulAurélien CarleNicolas ChanonJ ChoiDidier ContardoPierre DepasseCandan DozenHoumani El MamouniJean FaySusan GasconMaxime GouzevitchGérald GrenierBernard IlleImad Baptiste LaktinehMorgan LethuillierLaurent MirabitoStephane PerriesLucas TorterototMuriel Vander DoncktPatrice VerdierSébastien ViretDavit ChokheliIrakli LomidzeZviad TsamalaidzeValeria BottaLutz FeldKatja KleinMartin LipinskiDanilo MeuserAlexander PaulsNicolas RöwertMarius TeroerdeSvenja DiekmannAlena DodonovaNiclas EichDmitry EliseevMartin ErdmannPeter FackeldeyDaniele FasanellaBenjamin FischerThomas HebbekerKerstin HoepfnerFrancesco IvoneMing-Yan LeeLuca MastrolorenzoMarkus MerschmeyerA MeyerS MondalS MukherjeeDennis NollAndrzej NovakFabian NowotnyAndrey PozdnyakovYannik RathWahid RedjebHans ReithlerAlexander SchmidtSimon Christoph SchulerA SharmaLorenzo VigilanteSebastian WiedenbeckShawn ZaleskiChristian DziwokGünter FlüggeWael Haj AhmadOlena HlushchenkoThomas KressAndreas NowackOliver PoothAchim StahlTim ZiemonsAlexander ZotzHenriette Aarup PetersenMaria Aldaya MartinPaul AsmussSamuel BaxterMaryam BayatmakouOlaf BehnkeArmando Bermúdez MartínezS BhattacharyaAfiq Aizuddin Bin AnuarFreya BlekmanKerstin BorrasDavid BrunnerAlan CampbellAndrea CardiniChun ChengFederica ColombinaSandra Consuegra RodríguezGilson Correia SilvaMalinda de SilvaLeonid DidukhGuenter EckerlinDoris EcksteinLuis Ignacio Estevez BanosOleg FilatovElisabetta GalloAchim GeiserAngela GiraldiGuillaume GreauAlexander GrohsjeanValentina GuglielmiMoritz GuthoffAbideh JafariNur Zulaiha JomhariBenno KaechAshraf MohamedA KasemMatthias KasemannHessamoddin KavehClaus KleinwortRoman KoglerMatthias KommDirk KrückerWolfgang LangeDaina Leyva PerniaKaterina LipkaWolfgang LohmannRainer MankelIsabell-Alissandra Melzer-PellmannMikel Mendizabal MorentinJosry MetwallyA.B MeyerGabriele MilellaMichele MormileAndreas MussgillerAndreas NürnbergYounes OtaridDanyer Pérez AdánAlexei RasperezaBeatriz Ribeiro LopesJonas RübenachAlessia SaggioAndrej SaibelMykola SavitskyiMoritz SchamValerie ScheurerSimon SchnakePaul SchützeChristian SchwanenbergerMykyta ShchedrolosievRafael Eduardo Sosa RicardoDominic StaffordNicolas TononMerijn van de KlundertFederico VazzolerAna Ventura BarrosoRoberval WalshDavid WalterQ WangYiwen WenKatarzyna WichmannLucas WiensChristoph WissingSebastian WuchterlY YangAndré Zimermmane Castro SantosAnna AlbrechtSteffen AlbrechtMassimiliano AntonelloSamuel BeinLisa BenatoMatteo BonanomiPatrick ConnorKsenia de LeoMelanie EichKarim El MorabitFinn FeindtAlexander FröhlichChristoph GarbersErika GaruttiMohammadtaghi HajheidariJohannes HallerAndreas HinzmannHenrik Ronald JabuschGregor KasieczkaPhilip KeicherRobert KlannerWilliam KorcariTobias KramerViktor KutznerFinn LabeJohannes LangeArtur LobanovChristopher MatthiesAnkita MehtaLouis MoureauxMalte MrowietzAliya NigamovaYuval NissanAlexander PaaschKarla Josefina Pena RodriguezTobias QuadfaselMarcel RiegerOliver RiegerDaniel SavoiuPeter SchleperMatthias SchröderJoern SchwandtManuel SommerhalderHartmut StadieGeorg SteinbrückAlexandra TewsMoritz WolfSebastian BrommerMaximilian BurkartErik ButzRené CaspartThorsten ChwalekAlexander DierlammAlexander DrollNils FaltermannManuel GiffelsJan-Ole GosewischArtur GottmannFrank HartmannMaximilian HorzelaUlrich HusemannMarkus KluteRoland KoppenhöferStefan MaierSoureek MitraTh MüllerThomas MüllerMax NeukumMinseok OhGunter QuastKlaus RabbertzJohann RauserMatthias SchnepfDavid SeithIvan ShvetsovHans-Jürgen SimonisNicolò TrevisaniRalf UlrichJan van der LindenRalf Florian von CubeMichael WassmerSebastian WielandRoger WolfSebastian WozniewskiStefan WunschXunwu ZuoGeorgios AnagnostouPanagiotis AssiourasGeorgios DaskalakisAristotelis KyriakisAnna StakiaMagda DiamantopoulouDimitrios KarasavvasPantelis KontaxakisArkadios Manousakis-KatsikakisApostolos PanagiotouIoanna PapavergouNiki SaoulidouKonstantinos TheofilatosEirini TziaferiKonstantinos VellidisIlias ZisopoulosGeorgios BakasTheodoros ChatzistavrouKonstantinos KousourisIoannis PapakrivopoulosGeorgios TsipolitisAnna ZacharopoulouKosmas AdamidisIoannis BestintzanosIoannis EvangelouCostas FoudasParaskevas GianneiosChristos KamtsikisPanagiotis KatsoulisPanagiotis KokkasPolidamas Georgios Kosmoglou KioseoglouNikolaos ManthosIoannis PapadopoulosJohn StrologasMate CsanádKrisztián FarkasMahmod Moussa Abdelkhalek GadallahSándor LökösPéter MajorKoushik MandalGabriella PasztorAttila József RádlOlivér SurányiGabor Istvan VeresMárton BartókGyorgy BenczeCsaba HajduDezso HorvathFerenc SiklerViktor VeszpremiNoemi BeniSandor CzellarJános KarancsiJozsef MolnarZoltan SzillasiDaniel TeyssierPeter RaicsBalazs UjvariTamas Ferenc CsorgoFrigyes NemesTamas NovakJyoti BabbarSunil BansalSuman Bala BeriVipin BhatnagarGeetanjali ChaudharySushil ChauhanNitish DhingraRajat GuptaA KaurA KaurHarjot KaurManjit KaurS KumarPriyanka KumariMeena MeenaKaur SandeepTanvi SheokandJasbir SinghAayushi SinglaA.K VirdiAsar AhmedAshutosh BhardwajBrajesh C ChoudharyA KumarMohammad 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• Publié dans JHEP le 14/01/2026

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Résumé : Measurements of the inclusive and normalised differential cross sections are presented for the production of single top quarks in association with a W boson in proton-proton collisions at a centre-of-mass energy of 13 TeV. The data used were recorded with the CMS detector at the LHC during 2016–2018, and correspond to an integrated luminosity of 138 fb$^{−1}$. Events containing one electron and one muon in the final state are analysed. For the inclusive measurement, a multivariate discriminant, exploiting the kinematic properties of the events is used to separate the signal from the dominant $ \textrm{t}\overline{\textrm{t}} $ background. A cross section of $ 79.2\pm 0.9{\left(\textrm{stat}\right)}_{-8.0}^{+7.7}\left(\textrm{syst}\right)\pm 1.2\left(\textrm{lumi}\right) $ pb is obtained, consistent with the predictions of the standard model. For the differential measurements, a fiducial region is defined according to the detector acceptance, and the requirement of exactly one jet coming from the fragmentation of a bottom quark. The resulting distributions are unfolded to particle level and agree with the predictions at next-to-leading order in perturbative quantum chromodynamics.[graphic not available: see fulltext]

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Source

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Shreyasi AcharyaDagmar AdamovaAlexander AdlerGianluca Aglieri RinellaMichelangelo AgnelloNeelima AgrawalZubayer AhammedShakeel AhmadSang Un AhnIshaan AhujaAlexander AkindinovMohammad Al-TuranyDmitry AleksandrovBruno AlessandroHaidar Masud AlfandaJose Ruben Alfaro MolinaBushra AliYasir AliAndrea AliciNegin AlizadehvandchaliAnton AlkinJohan AlmeGiacomo AloccoTorsten AltIgor AltsybeevMustafa AnaamCristian AndreiAnton AndronicVenelin AnguelovFederico AntinoriPietro AntonioliAnuj ChandraNicole ApadulaL AphecetcheHarald AppelshaeuserSilvia ArcelliRoberta ArnaldiIonut Cristian ArseneMesut ArslandokAndre AugustinusRalf Peter AverbeckSizar AzizMohd Danish AzmiAngela BadalaYongwook BaekXiaozhi BaiRaphaelle Marie BailhacheYoshini BailungRenu BalaAlessandro BalbinoAlberto BaldisseriBartosz BalisDebjani BanerjeeZarina BanooRoberto BarberaLuca BarioglioMaria BarlouGergely Gabor BarnafoldiLee Stuart BarnbyValerie Ramillien BarretLeonardo Barreto de Oliveira CamposClara BartelsKlaus BarthEsther BartschFilippo BaruffaldiNicole BastidSumit BasuGuillaume BatigneDaniel BattistiniBoris BatyunyaDibakar BauriJose Luis Bazo AlbaIan Gardner BeardenCaitlin BeattiePascal BechtDebadatta BeheraIouri BelikovAilec Bell HechavarriaFrancesca BelliniRene BellwiedSvetlana BelokurovaVladimir BelyaevGyula BencediStefania Maria BeoleAlexandru BercuciYaroslav BerdnikovAnastasia BerdnikovaLuisa BergmannMihaela Gabriela BesoiuLatchezar BetevPartha Pratim BhaduriAnju BhasinInayat Rasool BhatMohammad Asif BhatBuddhadeb BhattacharjeeLivio BianchiNicola BianchiJaroslav BielcikJana BielcikovaJacek Bogumil BiernatAnte BilandzicGabor BiroSaikat BiswasJustin Thomas BlairDmitry BlauMihail Bogdan BlidaruNora BluhmeChristoph BlumeGianluigi BocaFriederike BockTea BodovaAlexey BogdanovStefano BoiJeongsu BokLaszlo BoldizsarAlexander BolozdynyaMarek BombaraPeter Matthew BondGermano BonomiHerve BorelAlexander BorissovHannah BossiElena BottaLars BratrudPeter Braun-MunzingerMarco BregantMichal BrozGiuseppe Eugenio BrunoMatthew Daniel BucklandDmitry BudnikovHenner BueschingStefania BufalinoOphelie BugnonPaul Alois BuhlerEdith Zinhle ButheleziJamila Bashir ButtAleksandr BylinkinSebastian Adam BysiakMengke CaiHelen Louise CainesAlberto CalivaErnesto Calvo VillarJuan Manuel Mejia CamachoPaolo CameriniFabio de Moraes CanedoMihai CarabasFrancesca CarnesecchiRobin Albert Andre CaronJavier Ernesto Castillo CastellanosFabio CatalanoCesar Ceballos SanchezIrakli ChakaberiaPritam ChakrabortySinjini ChandraSylvain ChapelandMarielle ChartierSubhasis ChattopadhyaySukalyan ChattopadhyayTonatiuh Garcia ChavezTiantian ChengCvetan Valeriev CheshkovBrigitte CheynisVasco Miguel Chibante BarrosoDavid Dobrigkeit ChinellatoEmma Sophia ChizzaliJaeyoon ChoSoyeon ChoPeter ChochulaPanagiotis ChristakoglouChristian Holm ChristensenPeter ChristiansenTatsuya ChujoMario CiaccoCorrado CicaloLuisa CifarelliFederico CindoloMichael Rudolf CiupekGiulia ClaiFabio Filippo ColamariaJonathan Samuel ColburnDomenico ColellaAlberto ColluManuel ColocciMatteo ConcasG. 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• Publié dans Phys.Lett.B le 31/10/2025

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Résumé : The production yields of non-prompt Ds+ mesons, namely Ds+ mesons from beauty-hadron decays, were measured for the first time as a function of the transverse momentum (pT) at midrapidity (|y|<0.5) in central and semi-central Pb–Pb collisions at a centre-of-mass energy per nucleon pair sNN=5.02TeV with the ALICE experiment at the LHC. The Ds+ mesons and their charge conjugates were reconstructed from the hadronic decay channel Ds+→ϕπ+, with ϕ→K−K+, in the 4<pT<36GeV/c and 2<pT<24GeV/c intervals for the 0–10% and 30–50% centrality classes, respectively. The measured yields of non-prompt Ds+ mesons are compared to those of prompt Ds+ and non-prompt D0 mesons by calculating the ratios of the production yields in Pb–Pb collisions and the nuclear modification factor RAA. The ratio between the RAA of non-prompt Ds+ and prompt Ds+ mesons, and that between the RAA of non-prompt Ds+ and non-prompt D0 mesons in central Pb–Pb collisions are found to be on average higher than unity in the 4<pT<12GeV/c interval with a statistical significance of about 1.6σ and 1.7σ, respectively. The measured RAA ratios are compared with the predictions of theoretical models of heavy-quark transport in a hydrodynamically expanding QGP that incorporate hadronisation via quark recombination.

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