Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Philippe RicaudPatrice MedinaPierre DurandJean-Luc AttiéEric BazilePaolo GrigioniMassimo Del GuastaBenji Pauly
• Organismes : Centre national de recherches météorologiques Laboratoire d'aérologie Laboratoire d'aérologie Laboratoire d'aérologie Centre national de recherches météorologiques Agenzia Nazionale per le nuove Tecnologie, l’energia e lo sviluppo economico sostenibile = Italian National Agency for New Technologies, Energy and Sustainable Economic Development Istituto Nazionale di Ottica DeltaQuad
• Publié dans Drones le 20/11/2018

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Résumé : The Antarctic atmosphere is rapidly changing, but there are few observations available in the interior of the continent to quantify this change due to few ground stations and satellite measurements. The Concordia station is located on the East Antarctic Plateau (75 • S, 123 • E, 3233 m above mean sea level), one of the driest and coldest places on Earth. Several remote sensing instruments are available at the station to probe the atmosphere, together with operational meteorological sensors. In order to observe in situ clouds, temperature, relative humidity and supercooled liquid water (SLW) at a high vertical resolution, a new project based on the use of an unmanned aerial vehicle (drone) vertical takeoff and landing from the DeltaQuad Company has been set up at Concordia. A standard Vaisala pressure, temperature and relative humidity sensor was installed aboard the drone coupled to an Anasphere SLW sensor. A total of thirteen flights were conducted from 24 December 2022 to 17 January 2023: nine technology flights and four science flights (on 2, 10, 11 and 13 January 2023). Drone-based temperature and relative humidity profiles were compared to (1) the balloon-borne meteorological observations at 12:00 UTC, (2) the ground-based microwave radiometer HAMSTRAD and (3) the outputs from the numerical weather prediction models ARPEGE and AROME. No SLW clouds were present during the period of observations. Despite technical issues with drone operation due to the harsh environments encountered (altitude, temperature and geomagnetic field), the drone-based observations were consistent with the balloon-borne observations of temperature and relative humidity. The radiometer showed a systematic negative bias in temperature of 2 • C, and the two models were, in the lowermost troposphere, systematically warmer (by 2-4 • C) and moister (by 10-30%) than the drone-based observations. Our study shows the great potential of a drone to probe the Antarctic atmosphere in situ at very high vertical resolution (a few meters).

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Fichiers liés : drones-07-00532.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Sona Malric-GarajovaFlorian FortunaFlorian PionElise MartinAdithya Raveendran ThottathilAudrey GuillemainAnnick DoanAnne LomascoloCraig B FauldsStéphanie BaumbergerLaurence FoulonBrigitte ChabbertHélène de BaynastPascal DubessayFabrice AudonnetEmmanuel BertrandGiuliano SciaraSandra Tapin-LinguaPaul-Henri DucrotPhilippe MichaudVéronique Aguié-BéghinEric Record
• Organismes : Biodiversité et Biotechnologie Fongiques Fractionnement des AgroRessources et Environnement Institut Jean-Pierre Bourgin - Sciences du végétal Institut Pascal Institut Jean-Pierre Bourgin - Sciences du végétal Institut Technologique Forêt Cellulose Bois-construction Ameublement Biodiversité et Biotechnologie Fongiques Biodiversité et Biotechnologie Fongiques Biodiversité et Biotechnologie Fongiques Institut Jean-Pierre Bourgin - Sciences du végétal Fractionnement des AgroRessources et Environnement Fractionnement des AgroRessources et Environnement Institut Pascal Génie des Procédés, Energétique et Biosystèmes Institut Pascal Biodiversité et Biotechnologie Fongiques Biodiversité et Biotechnologie Fongiques Institut Technologique Forêt Cellulose Bois-construction Ameublement Institut Jean-Pierre Bourgin - Sciences du végétal Institut Pascal Fractionnement des AgroRessources et Environnement Biodiversité et Biotechnologie Fongiques
• Publié dans Molecules le 31/10/2020

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Résumé : Here, we report work on developing an enzymatic process to improve the functionalities of industrial lignin. A kraft lignin sample prepared from marine pine was treated with the high-redoxpotential laccase from the basidiomycete fungus Pycnoporus cinnabarinus at three different concentrations and pH conditions, and with and without the chemical mediator 1-hydroxybenzotriazole (HBT). Laccase activity was tested in the presence and absence of kraft lignin. The optimum pH of PciLac was initially 4.0 in the presence and absence of lignin, but at incubation times over 6 h, higher activities were found at pH 4.5 in the presence of lignin. Structural changes in lignin were investigated by Fourier-transform infrared spectroscopy (FTIR) with differential scanning calorimetry (DSC), and solvent-extractable fractions were analyzed using high-performance size-exclusion chromatography (HPSEC) and gas chromatography-mass spectrometry (GC-MS). The FTIR spectral data were analyzed with two successive multivariate series using principal component analysis (PCA) and ANOVA statistical analysis to identify the best conditions for the largest range of chemical modifications. DSC combined with modulated DSC (MDSC) revealed that the greatest effect on glass transition temperature (Tg) was obtained at 130 U g cm −1 and pH 4.5, with the laccase alone or combined with HBT. HPSEC data suggested that the laccase treatments led to concomitant phenomena of oligomerization and depolymerization, and GC-MS revealed that the reactivity of the extractable phenolic monomers depended on the conditions tested. This study demonstrates that P. cinnabarinus laccase can be used to modify marine pine kraft lignin, and that the set of analytical methods implemented here provides a valuable tool for screening enzymatic treatment conditions.

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Fichiers liés : molecules-28-04873-v2.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Philippe ColsonPhilippe GautretJeremy DelerceHervé ChaudetPierre PontarottiPatrick ForterreRaphael TolaMarielle BedottoLéa DelormeWahiba BaderAnthony LevasseurJean‐christophe LagierMatthieu MillionNouara YahiJacques FantiniBernard La ScolaPierre‐edouard FournierDidier Raoult
• Organismes : Microbes Evolution Phylogénie et Infections Institut Hospitalier Universitaire Méditerranée Infection Institut Hospitalier Universitaire Méditerranée Infection Vecteurs - Infections tropicales et méditerranéennes Microbes Evolution Phylogénie et Infections Institut Hospitalier Universitaire Méditerranée Infection Vecteurs - Infections tropicales et méditerranéennes Institut Hospitalier Universitaire Méditerranée Infection Microbes Evolution Phylogénie et Infections Centre National de la Recherche Scientifique Institut Pasteur [Paris] Institut de Biologie Intégrative de la Cellule Hôpital de la Timone [CHU - APHM] Institut Hospitalier Universitaire Méditerranée Infection Microbes Evolution Phylogénie et Infections Institut Hospitalier Universitaire Méditerranée Infection Microbes Evolution Phylogénie et Infections Institut Hospitalier Universitaire Méditerranée Infection Institut Hospitalier Universitaire Méditerranée Infection Microbes Evolution Phylogénie et Infections Institut Hospitalier Universitaire Méditerranée Infection Microbes Evolution Phylogénie et Infections Microbes Evolution Phylogénie et Infections Institut Hospitalier Universitaire Méditerranée Infection Unité de Neurobiologie des canaux Ioniques et de la Synapse Unité de Neurobiologie des canaux Ioniques et de la Synapse Microbes Evolution Phylogénie et Infections Institut Hospitalier Universitaire Méditerranée Infection Institut Hospitalier Universitaire Méditerranée Infection Vecteurs - Infections tropicales et méditerranéennes Microbes Evolution Phylogénie et Infections Institut Hospitalier Universitaire Méditerranée Infection
• Publié dans Journal of Medical Virology le 25/10/2020

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Résumé : The nature and dynamics of mutations associated with the emergence, spread, and vanishing of SARS-CoV-2 variants causing successive waves are complex. We determined the kinetics of the most common French variant (“Marseille-4”) for 10 months since its onset in July 2020. Here, we analyzed and classified into subvariants and lineages 7453 genomes obtained by next-generation sequencing. We identified two subvariants, Marseille-4A, which contains 22 different lineages of at least 50 genomes, and Marseille-4B. Their average lifetime was 4.1 ± 1.4 months, during which 4.1 ± 2.6 mutations accumulated. Growth rate was 0.079 ± 0.045, varying from 0.010 to 0.173. Most of the lineages exhibited a bell-shaped distribution. Several beneficial mutations at unpredicted sites initiated a new outbreak, while the accumulation of other mutations resulted in more viral heterogenicity, increased diversity and vanishing of the lineages. Marseille-4B emerged when the other Marseille-4 lineages vanished. Its ORF8 gene was knocked out by a stop codon, as reported in SARS-CoV-2 of mink and in the Alpha variant. This subvariant was associated with increased hospitalization and death rates, suggesting that ORF8 is a nonvirulence gene. We speculate that the observed heterogenicity of a lineage may predict the end of the outbreak.

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Fichiers liés : Journal of Medical Virology - 2022 - Colson - The emergence spread and vanishing of a French SARS‐CoV‐2 variant (2).pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Laurent StrohmengerEric SauquetClaire BernardJeremie BonneauFlora BrangerAmélie BressonPierre BrigodeRémy BuzierOlivier DelaigueAlexandre DeversGuillaume EvinMaïté FournierShu-Chen HsuSandra LaniniAlban de LavenneThibault Lemaitre-BassetClaire MagandGuilherme Mendoza GuimarãesMax MenthaSimon MunierCharles PerrinTristan PodechardLéo RouchyMalak SadkiMyriam Soutif-BellengerFrançois TilmantYves TramblayAnne-Lise VéronJean-Philippe VidalGuillaume Thirel
• Organismes : Hydrosystèmes continentaux anthropisés : ressources, risques, restauration RiverLy - Fonctionnement des hydrosystèmes Chambre d'Agriculture du Vaucluse RiverLy - Fonctionnement des hydrosystèmes RiverLy - Fonctionnement des hydrosystèmes Etablissement Public Territorial du Bassin de la Dordogne - EPIDOR (FRANCE) Géoazur Hydrosystèmes continentaux anthropisés : ressources, risques, restauration Université de Limoges Hydrosystèmes continentaux anthropisés : ressources, risques, restauration RiverLy - Fonctionnement des hydrosystèmes Institut des Géosciences de l’Environnement ACTEON Hydrosystèmes continentaux anthropisés : ressources, risques, restauration Bureau de Recherches Géologiques et Minières Gestion de l'Eau, Acteurs, Usages Hydrosystèmes continentaux anthropisés : ressources, risques, restauration Milieux Environnementaux, Transferts et Interactions dans les hydrosystèmes et les Sols Hydrosystèmes continentaux anthropisés : ressources, risques, restauration Service santé de la faune et fonctionnement des écosystèmes agricoles Service fonctionnement, préservation et restauration des écosystèmes aquatiques continentaux et marins Hydrosystèmes continentaux anthropisés : ressources, risques, restauration SAFEGE NANTERRE Centre national de recherches météorologiques Hydrosystèmes continentaux anthropisés : ressources, risques, restauration RiverLy - Fonctionnement des hydrosystèmes Centre national de recherches météorologiques Hydrosystèmes continentaux anthropisés : ressources, risques, restauration AgroParisTech Hydrosystèmes continentaux anthropisés : ressources, risques, restauration Hydrosciences Montpellier Hydrosystèmes continentaux anthropisés : ressources, risques, restauration RiverLy - Fonctionnement des hydrosystèmes Hydrosystèmes continentaux anthropisés : ressources, risques, restauration
• Publié dans Hydrology and Earth System Sciences le 24/10/2020

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Résumé : Large datasets of long-term streamflow measurements are widely used to infer and model hydrological processes. However, streamflow measurements may suffer from what users can consider anomalies, i.e. non-natural records that may be erroneous streamflow values or anthropogenic influences that can lead to misinterpretation of actual hydrological processes. Since identifying anomalies is time consuming for humans, no study has investigated their proportion, temporal distribution, and influence on hydrological indicators over large datasets. This study summarizes the results of a large visual inspection campaign of 674 streamflow time series in France made by 43 evaluators, who were asked to identify anomalies falling under five categories, namely, linear interpolation, drops, noise, point anomalies, and other. We examined the evaluators' individual behaviour in terms of severity and agreement with other evaluators, as well as the temporal distributions of the anomalies and their influence on commonly used hydrological indicators. We found that inter-evaluator agreement was surprisingly low, with an average of 12 % of overlapping periods reported as anomalies. These anomalies were mostly identified as linear interpolation and noise, and they were more frequently reported during the low-flow periods in summer. The impact of cleaning data from the identified anomaly values was higher on low-flow indicators than on high-flow indicators, with change rates lower than 5 % most of the time. We conclude that the identification of anomalies in streamflow time series is highly dependent on the aims and skills of each evaluator, which raises questions about the best practices to adopt for data cleaning.

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Fichiers liés : hess-27-3375-2023.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : Célia ChamignonGeoffroy MallaretJulie RiviereMarthe VilotteSead ChadiAlejandra de Moreno de LeblancJean Guy LeblancFrédéric Antonio CarvalhoMarco PanePierre-Yves MoussetPhilippe LangellaSophie LafayLuis Bermúdez-Humarán
• Organismes : MICrobiologie de l'ALImentation au Service de la Santé Indigo Therapeutics Neuro-Dol MICrobiologie de l'ALImentation au Service de la Santé Génétique Animale et Biologie Intégrative MICrobiologie de l'ALImentation au Service de la Santé CERELA-CONICET [Tucuman, Argentina] CERELA-CONICET [Tucuman, Argentina] Neuro-Dol probiotical research Indigo Therapeutics MICrobiologie de l'ALImentation au Service de la Santé Indigo Therapeutics MICrobiologie de l'ALImentation au Service de la Santé
• Publié dans Biomolecules le 25/10/2020

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Résumé : Intestinal barrier integrity is essential in order to maintain the homeostasis of mucosal functions and efficient defensive reactions against chemical and microbial challenges. An impairment of the intestinal barrier has been observed in several chronic diseases. The gut microbiota and its impact on intestinal homeostasis is well described and numerous studies suggest the ability of some probiotic strains to protect the intestinal epithelial integrity and host homeostasis. In this work, we aimed to assess the beneficial effects of three Lactobacillus strains (Lacticaseibacillus rhamnosus LR04, Lacticaseibacillus casei LC03, and Lactiplantibacillus plantarum CNCM I-4459) and their mechanism of action in low-grade inflammation or neonatal maternal separation models in mice. We compared the impact of these strains to that of the well-known probiotic Lacticaseibacillus rhamnosus GG. Our results demonstrated that the three strains have the potential to restore the barrier functions by (i) increasing mucus production, (ii) restoring normal permeability, and (iii) modulating colonic hypersensitivity. Moreover, gene expression analysis of junctional proteins revealed the implication of Claudin 2 and Cingulin in the mechanisms that underlie the interactions between the strains and the host. Taken together, our data suggest that LR04, CNCM I-4459, and LC03 restore the functions of an impaired intestinal barrier.

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Fichiers liés : Chamignon2023_biomolecules-13-01295.pdf

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• Type de publi. : Chapître d'ouvrage
• Date de publi. : 01/01/2023
• Auteurs : Franck AccadbledRoger BadetS. BahrounOlivier BarbierWilliam BarnoudCécile BataillerThomas BauerPhilippe BeaufilsAntoine BertaniYohann BohuStéphane BoisgardPhilippe BoisrenoultFrançois BonnometMaxence BordesNicolas BouguennecThierry BoyerValérie BrioleFilippo CalannaOlivier CantinÉtienne CavaignacAntoine CazorFrançois ChalenconVincent ChassaingFranck ChotelCamille ChoufaniPhilippe ColombetT. CottebruneLouis CourtotThomas CucuruloJ. DartusDavid DejourFlorent DelangleGuillaume DemeyÉtienne DerocheStéphane DescampsR. Di FranciaPatrick DjianVictoria DuthonPascal Edouard ÉdouardMatthieu EhlingerRoger ErivanHenri FavreauJean-Marie FayardA. FerreiraC. FoisseyBenjamin FreychetAntoine GeromettaPhilippe GicquelThomas GicquelNicolas GraveleauOlivier GrimaudFrançois-Xavier GunepinSylvain GuyAlexandre HardyChristophe HuletChristophe JacquetChristophe JavoisJean-Yves JennyNabil JomaahCharles KajetanekFrédéric KhiamiPierre-Jean LambreyPhilippe LandreauNicolas LefevreRomain LetartreHoel LetissierMarie-Laure LouisThibaut LucenaSébastien LustigC. LutzVincent MarotJacques MenetreyGuillaume MesnardAlain MeyerCaroline MoutonBernard MoyenThomas NériMatthieu OllivierAïda OrceGilles PasquierSimon PelletierVincent PineauCharles PiogerJean-François PotelCésar PrazNicolas PujolSophie PutmanAlexandre RambaudFranck RémyHenri RobertFrédéric RongiérasRomain RousseauAbdou SbihiRomain SeilElvire ServienRenaud SiboniBertrand Sonnery-CottetHadrien StolzMathieu ThaunatPatricia ThoreuxCécile ToanenFrançois-Xavier VerdotGuillaume Villatte
• Organismes : Hôpital de la Croix-Rousse [CHU - HCL] Laboratoire de Biomécanique et Mécanique des Chocs Hôpital de la Croix-Rousse [CHU - HCL] Laboratoire de Biomécanique et Mécanique des Chocs

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2023
• Auteurs : G. AadBraden Keim AbbottBrad AbbottDale AbbottAdam Abed AbudKira AbelingDeshan Kavishka AbhayasingheHaider AbidiHass AbouzeidOssama AbouzeidNicola Louise AbrahamHalina AbramowiczHenso AbreuYiming AbulaitiBobby Samir AcharyaBaida AchkarShunsuke AdachiLennart AdamClaire Adam BourdariosLeszek AdamczykLukas AdamekJahred AdelmanMichael AdersbergerAytul AdiguzelSofia Adorni Braccesi ChiassiTim AdyeA.A. AffolderTony AffolderYoav AfikChristina AgapopoulouMerve Nazlim AgarasAnamika AggarwalCatalin AgheorghieseiJuan Antonio Aguilar SaavedraFaig AhmadovWaleed Syed AhmedXiaocong AiGiulio AielliShunichi AkatsukaTorsten AkessonEce AkilliAndrei AkimovKonie Al KhouryGian Luigi AlberghiJustin AlbertM.J. Alconada VerziniSara AlderweireldtMartin AleksaIgor AlexandrovCalin AlexaTheodoros AlexopoulosAlice AlfonsiFabrizio AlfonsiMuhammad AlhroobBabar AliMalik AlievGianluca AlimontiCorentin AllaireBenedict AllbrookeBenjamin William AllenPhilip Patrick AllportAlberto AloisioFrancisco AlonsoCristiano AlpigianiAzzah Aziz AlshehriElio Alunno CameliaManuel Alvarez EstevezMariagrazia AlviggiYara Do Amaral CoutinhoAlessandro AmblerLuca AmbrozChristoph AmelungDante AmideiSusana Patricia Amor dos SantosSimone AmorosoCherifa Sabrina AmroucheFenfen AnChristos AnastopoulosNansi AndariTimothy Robert AndeenChristoph Falk AndersJohn Kenneth AndersAttilio AndreazzaVictor AndreiChristopher Ryan AnelliStylianos AngelidakisAaron AngeramiAlexey AnisenkovAlberto AnnoviClaire AntelMatthew Thomas AnthonyEgor AntipovMario AntonelliDaniel Joseph AntrimFabio AnulliMasato AokiJavier Alberto Aparisi PozoMarco AparoLudovica Aperio BellaJuan Pedro Araque EspinosaVictor Araujo FerrazR.Araujo PereiraChiara ArcangelettiAyana Tamu ArceFrancisco Anuar ArduhJean-Francois ArguinSpyros ArgyropoulosSpyridon ArgyropoulosJan-Hendrik ArlingAaron James ArmbrusterAlexander ArmstrongOlivier ArnaezHannah ArnoldZulit Paola Arrubarrena TameGiacomo ArtoniSebastian ArtzShoji AsaiThanawat AsawatavonvanichNedaa Alexandra AsbahEleni Myrto AsimakopoulouLily AsquithJihad AssahsahKetevi Adikle AssamaganRobert AstalosRyan Justin AtkinMarkus Julian AtkinsonNaim Bora AtlayHicham AtmaniKamil AugstenConstantin P. BachasMohamad Kassem AyoubGeorges AzuelosHenri BachacouKonstantinos BachasMoritz BackesKarl Filip BackmanPaolo BagnaiaH. BahrasemaniMarzieh BahmaniSina BahrasemaniAdam BaileyVirginia BaileyJohn BainesChristos BakalisKeith BakerPepijn Johannes BakkerDebottam Bakshi GuptaShyam BalajiEvgenii BaldinPetr BalekFabrice BalliWilliam Keaton BalunasJohannes BalzElzbieta BanasAnjishnu BandyopadhyaySw. BanerjeeSwagato BanerjeeA.A. E. BannouraLiron BarakWilliam Mickael BarbeElisabetta BarberioDario BarberisMarlon Benoit BarberoGregory BarbourTeresa BarillariMartin BarisitsJason Tyler Colt BarkelooTim BarklowTimothy BarklowRotem BarneaBruce M. BarnettMichael BarnettZ. Barnovska-BlenessyToni BaroncelliAntonio BaroncelliGaetano BaroneAlan BarrLaura Barranco NavarroFernando Barreiro AlonsoJoao Barreiro Guimaraes da CostaSergey BarsovRainer BartoldusGiovanni BartoliniAdam Edward BartonPavol BartosArtem BasalaevAlexander BasanAhmed BassalatMatthew Joseph BassoRichard BatesSouad BatlamousRichard BatleyBinish BatoolMarco BattagliaMatteo BauceFlorian BauerKevin Thomas BauerHarinder Singh BawaJames BeachamTristan BeauPierre-Hugues BeaucheminFabian BechererPhilip BechtleHelge Christoph BeckHans Peter BeckKathrin BeckerCyril Pascal BecotAyda BeddallAndrew BeddallVadim BednyakovMatteo BedognettiChris BeeChristopher BeeThomas BeermannMarcia BegalliMichael BegelArabinda BeheraJanna Katharina BehrFlorian BeisiegelAndrew Stuart BellGideon BellaLorenzo BellagambaAlain BellerivePanagiotis BellosKonstantin BeloborodovKonstantin BelotskiyNikita BelyaevDriss BenchekrounNectarios BenekosYan BenhammouDoug BenjaminDouglas BenjaminMathieu BenoitJim BensingerJames BensingerStan BentvelsenLydia Audrey BeresfordMatteo Mario BerettaDavid BergeElin Bergeaas KuutmannNicolas BergerBenedikt Ludwig BergmannLaura Jean BergstenJuerg BeringerSimon BerlendisGregorio BernardiCatrin BerniusFlorian Urs BernlochnerTracey BerryPeter BertaClaudia BertellaIain BertramOlga Bessidskaia BylundNathalie BessonAgni BethaniSiegfried BethkeAlessandra BettiAdrian BevanJulien-Christopher BeyerDeb Sankar BhattacharyaPrajita BhattaraiRunyu BiRiccardo Maria BianchiOtmar BiebelDustin BiedermannRafal BielskiKatharina BierwagenNicolo Vladi BiesuzMichela BigliettiT.R. V. BilloudMarcello BindiAhmet BingulCesare BiniSilvia BiondiMattias BirmanTobias BisanzJyoti Prakash BiswalDiptaparna BiswasAlexander BitadzeCarsten BittrichKristian BjoerkeTomas BlazekIngo BlochCraig BlockerAndrew James BlueUlla BlumenscheinUlrike BlumenscheinGerjan BobbinkViktor BobrovnikovSimona BocchettaAndrea BocciDaniela BoernerDanijela BogavacAlexander BogdanchikovChristian BohmVeronique BoisvertPetar BokanTomasz BoldArthur Eugen BolzMarco BombenMarcella BonaJohan Sebastian BonillaMaarten BoonekampCallum Dale BoothHanna Maria Borecka-BielskaLucas Santiago BorgnaAnatoli BorisovGuennadi BorissovJona BortfeldtJonathan BortfeldtDaniela BortolettoDavide BoscheriniMartine Fernandez-BosmanJ.D. Bossio SolaKhalil BouaoudaJoseph BoudreauE.V. Bouhova-ThackerEvelina Vassileva Bouhova-ThackerDjamel Eddine BoumedieneSarah BoutleAntonio BoveiaJamie BoydJames BoydDiallo BoyeIgor BoykoAdam BozsonJuraj BracinikNihal BrahimiGerhard Immanuel BrandtOleg BrandtFrued Erik BrarenBenjamin Paul BrauJim BrauWill Breaden MaddenJames BrauWilliam Dmitri Breaden MaddenKurt BrendlingerLydia BrennerRichard BrennerShikma BresslerBernard BrickweddeDaniel Lawrence BriglinDavid BrittonDave BrittonDaniel Andreas BritzgerIan BrockRaymond BrockGustaaf BrooijmansWilliam King BrooksElizabeth BrostJames BroughtonPawel Bruckman de RenstromDusan BrunckoAlessia BruniGraziano BruniLucrezia Stella BruniSalvatore BrunoMarco BruschiNello BruscinoPatrick Eugene BryantLene Kristian BryngemarkTrygve BuanesQuentin BuatPeter BuchholzAndy BuckleyAndrew BuckleyIoulian BudagovMagnar Kopangen BuggeFelix BuhrerOleg BulekovTyler James BurchSergey BurdinCarsten BurgardAngela Maria BurgerBlake Oliver BurghgraveWilliam ButtingerJon BurrJonathan Thomas BurrCharles BurtonJackson Carl BurzynskiVolker BuescherEric BuschmannPeter John BusseyJohn Mark ButlerCraig Macleod ButtarJonathan ButterworthPierfrancesco ButtiWill ButtingerCarlos Josue Buxo VazquezAdrian BuzatuAlexey BuzykaevAleksey BuzykaevGrazia CabrasSusana Cabrera UrbanDavide CaforioHuacheng CaiValentina CairoOrhan CakirNoemi CalacePaolo CalafiuraAlessandro CalandriGiovanni CalderiniPhilippe CalfayanGiuseppe CalleaLuiz CalobaAlessandro CaltabianoSergio Calvente LopezDavid CalvetSamuel CalvetThomas Philippe CalvetMilene CalvettiReina Coromoto Camacho ToroStefano CamardaDaniel Camarero MunozPaolo CamarriDavid CameronClement CamincherSimone CampanaMario CampanelliAlessandra CamplaniAngel Fernando Campoverde QuezadaVincenzo CanaleAuriane CanesseMarc Bret CanoJosu Cantero GarciaTingting CaoYumeng CaoM.D. M. Capeans GarridoMarcella CapuaRoberto CardarelliFabio CardilloGiovandomenico CarducciIna CarliTancredi CarliGiampaolo CarlinoB.T. CarlsonBenjamin Taylor CarlsonEvan Michael CarlsonLeonardo CarminatiRebecca CarneySascha CaronEdson Carquin LopezSonia CarraJ.W. S. CarterPilar Casado LechugaMaria Pilar CasadoAlbert Francis CashaRemco Johannes CastelijnFlorencia Luciana CastilloLucia Castillo GarciaVictoria Castillo GimenezNuno CastroAndrea CatinaccioJames CatmoreAriella CattaiViviana CavaliereEmanuele CavallaroMatteo Cavalli-SforzaVincenzo CavasinniEmre CelebiLeonor Cerda AlberichKarel CernyAugusto Santiago CerqueiraAlex CerriAlessandro CerriLucio CerritoFabio CeruttiAlberto CervelliSerkant CetinZakaria ChadiDhiman ChakrabortyJay ChanTerry Ws ChanChen-Hsun ChanWing Sheung ChanWai Yuen ChanJohn Derek ChapmanBakar ChargeishviliDave CharltonThomas Paul CharmanChav Chhiv ChauSiinn CheSergei ChekanovSergey ChekulaevG. ShelkovBoping ChenCheng ChenChunhui ChenHucheng ChenJing ChenJue ChenJiayi ChenShion ChenShenjian ChenXin ChenYu-Heng ChenHok Chuen Tom ChengHuajie ChengAlexander CheplakovEvgeniya CheremushkinaRajaa Cherkaoui El MoursliElliott CheuKingman CheungThibault ChevaleriasLaurent ChevalierVitaliano ChiarellaGiorgio ChiarelliGabriele ChiodiniAndrew Stephen ChisholmAdrian ChitanI-Huan ChiuJustin ChiuMihail ChizhovKyungeon ChoiArthur ChomontSofia ChouridouE.Y. S. ChowYun Sang ChowMing Chung ChuXiaotong ChuJiri ChudobaJanusz ChwastowskiLadislav ChytkaDavide CieriKrzysztof CieslaDiane CincaVladimir CindroIrina Antonela CioaraAlessandra CiocioFrancesco CirottoZ.H. CitronMauro CitterioDan Andrei CiubotaruBianca Monica CiunguAllan ClarkFelix ClarkMichael Ryan ClarkPhilip ClarkChristophe ClementYann CoadouMarina CobalAndrea CoccaroJames Herbert CochranRafael Coelho Lopes de SaHadar CohenA.E. C. CoimbraBrian ColeAuke-Pieter ColijnJohann CollotPatricia Conde MuinoSimon ConnellIan Allan ConnellySerban ConstantinescuFrancesco ConventiA.M. Cooper-SarkarFelix CormierKyle James Read CormierLouie Dartmoor CorpeMassimo CorradiEric Edward CorriganFrancois CorriveauArely Cortes-GonzalezMaria Jose Costa MezquitaFrancesco CostanzaDavide CostanzoGlen CowanJames William CowleyJonathan CraneKyle Stuart CranmerSamuel Joseph CrawleyRachael Ann CreagerS. 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• Organismes : Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique Subatomique et de Cosmologie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Subatomique et de Cosmologie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Subatomique et de Cosmologie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Calcul de l'IN2P3 Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie
• Publié dans Nature Phys. le 26/11/2025

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Résumé : Electroweak symmetry breaking explains the origin of the masses of elementary particles through their interactions with the Higgs field. Besides the measurements of the Higgs boson properties, the study of the scattering of massive vector bosons with spin one allows the nature of electroweak symmetry breaking to be probed. Among all processes related to vector-boson scattering, the electroweak production of two jets and a $Z$-boson pair is a rare and important one. Here we report the observation of this process from proton-proton collision data corresponding to an integrated luminosity of 139 fb$^{-1}$ recorded at a centre-of-mass energy of 13 TeV with the ATLAS detector at the Large Hadron Collider. We consider two different final states originating from the decays of the $Z$-boson pair - one containing four charged leptons and the other containing two charged leptons and two neutrinos. The hypothesis of no electroweak production is rejected with a statistical significance of 5.7 $\sigma$, and the measured cross-section for electroweak production is consistent with the standard model prediction. In addition, we report cross-sections for inclusive production of a $Z$-boson pair and two jets for the two final states.

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