Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 15/10/2026
• Auteurs : Nacim BetrouniMaia KetelersRomain ViardCamille NaïdjiAnne Sophie RollandCharlotte LalouxCaroline MoreauGrégory KuchcinskiAlexandre EusebioStéphane ThoboisElodie HainqueJean-Philippe BrandelOlivier J. RascolChristine Brefel-CourbonSophie DrapierCaroline GiordanaAna MarquesDavid MaltêteDominique GuehlLucie HopesTiphaine RouaudBéchir JarrayaIsabelle BenatruThomas WirthFazia Mélissa TirMarie ChupinJean-Christophe CorvolDavid Devos
• Organismes : Lille Neurosciences & Cognition - U 1172 Lille Neurosciences & Cognition - U 1172 Plateformes Lilloises en Biologie et Santé - UAR 2014 - US 41 Lille Neurosciences & Cognition - U 1172 Lille Neurosciences & Cognition - U 1172 Plateformes Lilloises en Biologie et Santé - UAR 2014 - US 41 Lille Neurosciences & Cognition - U 1172 Département de neurologie [Lille] Lille Neurosciences & Cognition - U 1172 Plateformes Lilloises en Biologie et Santé - UAR 2014 - US 41 Departement de Neuroradiologie [Lille] Institut de Neurosciences de la Timone Service de neurologie C - Centre expert Parkinson Équipe Pathophysiologie de la maladie de Parkinson et des troubles associés - Pathophysiology of Parkinson's disease and related disorders Team AP-HP - Hôpital de la Pitié Salpêtrière Institut du Cerveau = Paris Brain Institute Fondation Ophtalmologique Adolphe de Rothschild [Paris] Toulouse NeuroImaging Center Centre d'investigation clinique de Toulouse Toulouse NeuroImaging Center Centre d'investigation clinique de Toulouse Service de Neurologie [Rennes] = Neurology [Rennes] Service de Neurologie [CHU Nice] Thérapie guidée par l'image Service de neurologie [Rouen] Différenciation et communication neuronale et neuroendocrine Institut des Maladies Neurodégénératives [Bordeaux] Service de neurologie [CHRU Nancy] Hôpital Guillaume-et-René-Laennec [CHU Nantes] Neuroimagerie cognitive - Psychologie cognitive expérimentale CIC de Poitiers – Centre d'investigation clinique de Poitiers (CIC 1402) Institut de Génétique et de Biologie Moléculaire et Cellulaire Fédération de Médecine Translationnelle de Strasbourg Neurologie [CHU Amiens] Laboratoire de Neurosciences Fonctionnelles et Pathologies - UR UPJV 4559 Institut du Cerveau = Paris Brain Institute AP-HP - Hôpital de la Pitié Salpêtrière Institut du Cerveau = Paris Brain Institute Lille Neurosciences & Cognition - U 1172 Département de Pharmacologie Médicale [Lille]
• Publié dans Neurobiology of Disease le 23/10/2020

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Résumé : Background: Levodopa is the gold-standard therapy for motor symptoms in Parkinson's disease (PD). However, individual responses vary substantially among patients, and the biological mechanisms underlying this heterogeneity remain incompletely understood. Objective: This study aimed to investigate the neural substrates associated with variability in levodopa responsiveness using multimodal magnetic resonance imaging (MRI). Methods: Data were retrieved for this ancillary study from the PREDISTIM cohort, that aims to define predictors for deep brain stimulation outcomes. Patients were stratified through a data-driven clustering approach according to their dopa responsiveness and disease duration. MRI analyses included T1-weighted imaging and multi-echo fast gradient-echo sequences. Structural and iron-sensitive MRI measures were compared across clusters within key regions. Results: A three-phenotype response pattern previously reported in the Parkinson's Progression Markers Initiative dataset was identified, extending beyond the conventional binary classification of good (C3) and poor responders (C1). An intermediate phenotype (C2) showed preserved pharmacological responsiveness despite longer disease duration. Structural MRI revealed significant putaminal atrophy in this cluster. In contrast, patients in cluster C1 exhibited reduced grey matter in the temporo-parietal operculum and inferior frontal cortex as well as an increased iron deposition in the substantia nigra and globus pallidus internus. Conclusion: These findings, that should be validated in other populations, suggest that variability in levodopa responsiveness reflects distinct neurobiological substrates rather than a simple continuum of disease severity. Integrating markers of structural degeneration and iron-related microenvironmental changes within basal ganglia-cortical circuits may improve phenotypic stratification and support the development of precision therapeutic strategies in PD.

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Fichiers liés : 1-s2.0-S096999612600344X-main.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 13/10/2026
• Auteurs : Raquel BarbosaPaulo André Dias BastosOlivier J. RascolJean-Christophe CorvolFabienne Ory MagneChristine Brefel-CourbonClémence LeungLouise-Laure MarianiLuc DefebvreNicolas CarrièreCaroline GiordanaCharlotte HéraudChloé LaurencinStéphane PrangePhilippe RémyLucie HopesJean-Luc HouetoPauline PrinClaire ThiriezAnne Doé de MaindrevilleIsabelle BenatruAnne-Gaëlle CorbilléSilvia Di LeggeOuhaïd Lagha-BoukbizaVincent SchneiderStéphane GrimaldiGiovanni CastelnovoFazia Mélissa TirDavid MaltêteAlexandra Foubert-SamierAna MarquesSophie DrapierMargherita Fabbri
• Organismes : Département Neurologie [CHU Toulouse] Toulouse NeuroImaging Center Centre d'investigation clinique de Toulouse Toulouse NeuroImaging Center Centre d’Excellence en Maladies Neurodégénératives Toulouse NeuroImaging Center Centre d'investigation clinique de Toulouse Institut du Cerveau = Paris Brain Institute Centre d'investigation clinique Neurosciences [CHU Pitié Salpêtrière] Toulouse NeuroImaging Center Centre Hospitalier Universitaire de Toulouse Centre d'investigation clinique de Toulouse Toulouse NeuroImaging Center Département Neurologie [CHU Toulouse] Institut du Cerveau = Paris Brain Institute Lille Neurosciences & Cognition - U 1172 Lille Neurosciences & Cognition - U 1172 Centre Hospitalier Régional Universitaire [CHU Lille] Service de Neurologie [CHU Nice] Université Côte d'Azur Service de neurologie C - Centre expert Parkinson Équipe Pathophysiologie de la maladie de Parkinson et des troubles associés - Pathophysiology of Parkinson's disease and related disorders Team Hospices Civils de Lyon Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Université de Lyon IMRB - "NeuroPsychologie Interventionnelle" [Créteil] CHRU Nancy - Hôpitaux de Brabois Service de Neurologie [CHU Limoges] Institut des Neurosciences de Montpellier CHU Montpellier = Montpellier University Hospital Service de Neurologie [Strasbourg] Service de neurologie [Reims] Service de neurologie [CHU de Poitiers] Université de Poitiers – UFR Santé [Faculté de Médecine et de Pharmacie] Centre Hospitalier Universitaire de Nantes = Nantes University Hospital CIC Plurithématique de Nantes Centre Hospitalier Intercommunal Aix-Pertuis Service de Neurologie [Strasbourg] Service de neurochirurgie [CHU Dijon] Neurologie, maladies neuro-musculaires [Hôpital de la Timone - APHM] Service de Neurologie [CHU Nimes] Neurologie [CHU Amiens] Laboratoire de Neurosciences Fonctionnelles et Pathologies - UR UPJV 4559 Service de neurologie [Rouen] Neuroendocrine, Endocrine and Germinal Differentiation Communication Institut des Maladies Neurodégénératives [Bordeaux] CHU Clermont-Ferrand Thérapie guidée par l'image Service de Neurologie [Rennes] = Neurology [Rennes] Centre d'Investigation Clinique [Rennes] Département Neurologie [CHU Toulouse] Toulouse NeuroImaging Center
• Publié dans Neurology le 01/11/2020

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Résumé : Background and Objectives Recent reports have suggested that levodopa exposure may contribute to freezing of gait (FOG), but this relationship remains controversial because of confounding by disease severity and duration. Our goal was to assess the relationship between levodopa use and FOG incidence and severity. Methods We studied 2 prospective, multicentric cohorts: NS-Park and Parkinson's Progression Markers Initiative (PPMI). Patients with ≥2 visits were selected. Three nested subcohorts were defined based on disease duration, baseline FOG, and levodopa exposure. FOG was assessed using the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Part II 2.13. Analyses included mixed-effects ordered logistic regression to evaluate FOG severity and Kaplan-Meier and Cox proportional hazards models to assess incident FOG. Models adjusted for disease duration, Hoehn and Yahr (H&Y) stage, and MDS-UPDRS Part III scores. Results A total of 25,602 patients with Parkinson disease from the NS-Park (mean age 68.3 ± 29.1, 42% female) and 1,441 from the PPMI (mean age 62.9 ± 9.8, 37% female) cohorts were included. In unadjusted analyses with the NS-Park cohort, levodopa use was associated with higher FOG severity and incidence, but this association was no longer statistically significant in the PPMI cohort. In mixed-effects ordinal logistic regression models adjusting for disease duration/severity, levodopa status showed a nonsignificant effect size on FOG (NS-Park odds ratio [OR] 1.84, 95% CI 0.94–3.61, p = 0.074; PPMI OR 0.76, 95% CI 0.38–1.51, p = 0.430), while disease duration (NS-Park OR 4.4, 95% CI 3.01–6.29, p = 6.0e-15; PPMI OR 6.97, 95% CI 5.05–9.63, p = 4.7e-32), Hoehn & Yahr stage (NS-Park OR 6.8, 95% CI 3.52–13.08, p = 1.059e-08; PPMI OR 1.5, 95% CI 0.96–2.22, p = 0.073), and MDS-UPDRS-III score (NS-Park OR 1.85, 95% CI 1.38–2.49, p = 4.34e-05; PPMI OR 2.00, 95% CI 1.67–2.39, p = 2.4e-14) were independently associated with greater FOG severity. No statistically significant association was observed between future levodopa exposure and de novo FOG incidence. In turn, FOG incidence was driven by the H&Y (NS-Park: hazard ratio [HR] 1.94, 95% CI 1.68–2.23; PPMI: HR 1.78, 95% CI 1.47–2.17) and MDS-UPDRS III (NS-Park: HR 1.40, 95% CI 1.07–1.83; PPMI: HR 1.26, 95% CI 1.17–1.36). Discussion No significant or consistent association between levodopa exposure and FOG severity or incidence was observed after adjustment for disease duration and severity, with the effect estimates significantly attenuated despite residual uncertainty.

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• Type de publi. : Article dans une revue
• Date de publi. : 13/10/2026
• Auteurs : Paul GuedeneyJulio Farjat-PasosNicolas MeneveauClaire DauphinMaik GrundekenJeremie AbtanMeyer ElbazMatthieu BesuttiJules MesnierLars WittePatrick OhlmannGora NdiayeMarion KiblerMarcel Am BeijkRobbert de WinterGaetano Maria de FerrariPaolo BorettoRomain TresorierThibaut PommierVincent RouleFarzin BeyguiNicolas MartinPaul GabrionHakim BenamerMatthieu PerierVincent AuffretEmmanuel BoiffardFabien ArabuckiStéphanie RouanetMarie DupuyFlorent HuangLouis GiovachiniMichel ZeitouniNadjib HammoudiJohanne SilvainJosep Rodés-CabauGilles MontalescotNiki ProcopiAnthony ElhadadPerrine DevosThomas WalletCamille GrangerEric VicautArthur SouquetAlexis HermidaLaurent LeborgneBenjamain HaberPaul BarsoumNadjib LehbibMarie Hauguel-MoreauGabriel ChevrotGuillaume CaylaBenoit GerardinJean Noel AndarelliGregoire AlbenqueJulien RosencherSabrina UhryCamille SiegelLaurent PayotFarouk AbchaEmmanuel GallAlexandre LafontLaszlo LevaiAnthony MattaPhilippe GarotGilles RioufolJean-Michel ClercRadwane HakimPaul LuporsiChedi YousfiFabien HuetPierre AubryBrahim Meftout
• Organismes : Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases Quebec Heart and Lung Institute Université Marie et Louis Pasteur CHU Clermont-Ferrand Alliance française pour les essais cliniques cardio-vasculaires - French Alliance for Cardiovascular Trials AP-HP - Hôpital Bichat - Claude Bernard [Paris] Service Cardiologie [CHU Toulouse] Centre d'investigation clinique de Toulouse Centre Hospitalier Régional Universitaire de Besançon Université Marie et Louis Pasteur Assistance publique - Hôpitaux de Paris Service de cardiologie [CHU Bichat] Pôle d'Activité Médico-Chirurgicale Cardio-Vasculaire [Strasbourg] Médecine Cardiovasculaire Translationnelle Centre Hospitalier Universitaire [Strasbourg] Nouvel Hôpital Civil de Strasbourg Université de Strasbourg Academic Medical Center - Academisch Medisch Centrum [Amsterdam] Università degli studi di Torino = University of Turin CHU Clermont-Ferrand Physiopathologie et épidémiologie cérébro-cardiovasculaires [Dijon] CHU Caen Normandie – Centre Hospitalier Universitaire de Caen Normandie Université de Caen Normandie Cardiologie [CHU Amiens] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Laboratoire Traitement du Signal et de l'Image AP-HP - Hôpital de la Pitié Salpêtrière Unité de Recherche sur les Maladies Cardiovasculaires, du Métabolisme et de la Nutrition = Research Unit on Cardiovascular and Metabolic Diseases Cardiologie [CHU Amiens] Périnatalité et Risques Toxiques - UMR INERIS_I 1 UPJV
• Publié dans Circulation le 29/10/2020

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 07/10/2026
• Auteurs : Duchesse-Lacours Mbadinga ZamarPhilippe RanochaMélanie K RichKatharina MelkonianTatiana VerniéTifenn PellenNicolas VigneronJean KellerFrédéric DomergueYves MartinezAurélie Le RuChristophe DunandPierre-Marc Delaux
• Organismes : Laboratoire de Recherche en Sciences Végétales Laboratoire de Recherche en Sciences Végétales LRSV-Evolution des Interactions Plantes-Microorganismes Laboratoire de Recherche en Sciences Végétales Laboratoire de Recherche en Sciences Végétales Laboratoire de Recherche en Sciences Végétales Laboratoire de Recherche en Sciences Végétales Laboratoire de Recherche en Sciences Végétales Laboratoire de biogenèse membranaire Plateforme TRI FR-AIB Plateforme TRI FR-AIB Laboratoire de Recherche en Sciences Végétales LRSV-Evolution des Interactions Plantes-Microorganismes

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Résumé : Abstract How the functional innovations that enabled plants to first colonize land 450 million years ago evolved remains puzzling. Here, we show that the gain of a single family of enzymes was pivotal in the evolution of two of these innovations, the cuticle that protect plants from dehydration and UV light, and the Arbuscular Mycorrhizal symbiosis promoting water and nutrient uptake. We show that functional phosphatase domain Glycerol-3-Phosphate Acyl Transferase (p-GPATs) evolved in the first land plants, concomitantly with the cuticle and symbiosis. Mutation of two p-GPATs from the liverwort Marchantia paleacea is sufficient to abolish both cuticle formation and AM symbiosis, leading to major developmental defects. We propose that the evolution of p-GPATs in land plants acted as a two birds-one stone innovation, diverting intracellular lipids to the extracellular space and providing a simple path to the evolution of two traits essential for the colonization of land.

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 06/10/2026
• Auteurs : Roel AaijMohammed AbdelfatahAhmed Sameh Wagih AbdelmottelebCarlos Abellan BetetaFernando Jesus AbudinénThomas AckernleyAyomide Matthew AdefisoyeBernardo AdevaMarco AdinolfiPatrik Harri AdlarsonChristina AgapopoulouChristine Angela AidalaSimon AkarKazuyoshi AkibaHussain Hassan A Al SalehPietro AlbicoccoJohannes AlbrechtRamunas AleksiejunasFederico AlessioPaula Alvarez CartelleAntonio Augusto AlvesSandra AmatoJake Lewis AmeyYasmine AmhisZachariah Benjamin AmosLiupan AnLucio AnderliniPasquale AndreolaMirco AndreottiSergio Andres EstradaAlessia AnelliDong AoCarolina ArataFlavio ArchilliZaratsyan AregMatteo ArgentonSergio Arguedas CuendisLisa ArnoneMarina ArtusoElie AslanidesRita Ataíde da SilvaMichele AtzeniBenjamin AudurierJuliette AuthierDavid BacherIrene Bachiller PereaSebastian BachmannMarie BachmayerJohn BackMaoze BaiZiyu BaiVladislav BalaguraAnna BalboniWander BaldiniZachary BaldwinLuca BalzaniHaoran BaoJuan Baptista de Souza LeiteCarlos Javier Barbero PretelIvanildo Rui BarbosaWilliam David BarkerRoger BarlowMikhail BarnyakovSophie BaronSergey BarsukWilliam BarterJustin BartzSaliha BashirBaasansuren BatsukhPiera BattistaAli BavarcheeAurelio BayAnja BeckMaik BeckerFranco BedeschiIgnacio BediagaNoah Albin BehlingSamuel BelinAlberto BellavistaIvan BelyaevGiovanni BencivenniEli Ben-HaimJulie BerkeyRoland BernetAlessandro BertolinLukas Frederic BertschFederico BettiJosh BexOleg BezshyykoSenjuti BhattacharyaMartin Stefan BiekerNicolo Vladi BiesuzAlice BiolchiniMatthew BirchFionn Caitlin Ros BishopAlexander BitadzeAndrea BizzetiThomas BlakeFrederic BlancJonah Evan BlankSteven BluskJulian Alexander BoelhauveOscar Boente GarciaThomas BoettcherAbhishek BohareCarolina BolognaniRiccardo BonacciAleksandar BordeliusFederica BorgatoSilvia BorghiMartino BorsatoJozef Tomasz BorsukElia BottalicoSonia Amina BouchibaMarcelo BovillThemistocles BowcockAlexandre BoyerConcezio BozziJames Daniel BrandenburgAlexandre Brea RodriguezNils BreerChristopher BreitfeldJolanta BrodzickaJames David BrownEmma BuchananMarta Burgos MarcosChristopher BurrErich Vito ButeraClarissa ButiJordy Sebastiaan ButterWiktor ByczynskiSandro CadedduHao CaiYichao CaiYuman CaiAlois CailletRoberto CalabreseLukas CaleficeMarta CalviMiriam Calvo GomezPatricia Camargo MagalhaesJose Ivan Cambon BouzasPierluigi CampanaAndrea Fulvio CampomagnaniAlexandre CamposAngel Fernando Campoverde QuezadaYuhang CaoSimone CapelliMarco CaporaleLorenzo CapriottiRonald Gerardo Caravaca-MoraAngelo CarboneLidia Carcedo SalgadoRoberta CardinaleAlessandro CardiniPaolo CarnitiLeon David CarusRowina CasparyGianluigi CasseMarco CattaneoGiovanni CavalleroViola CavalliniSara CelaniIrene CelestinoSara CesareAbbie Jane ChadwickMatthew CharlesPhilippe CharpentierEvridki ChatzianagnostouRacha CheaibMaximilien ChefdevilleChen ChenJou-An ChenShanzhen ChenZewen ChenAlex Chen HuMostafa CherifSerhii ChernyshenkoXenofon ChiotopoulosGleb ChizhikVeronika ChobanovaAlec ChristakakisMarcin ChrzaszczYanbo ChuVladimir ChulikovPaolo CiambroneXabier Cid VidalPierfrancesco CifraPeter ClarkeMarco ClemencicHarry CliffJoel ClosierCarlos Eduardo Cocha ToapaxiVictor CocoArianna CodoviniChiara Silvia CodoviniJulien CoganEric CognerasLucian CojocariuSpencer Edward CollavitiPaula CollinsTommaso ColomboMarco ColonnaAlbert Comerma-MontellsLiliana CongedoJames ConnaughtonAndrea ContuNaomi CookeAnnalea CoralloGiulio CordovaChristian Andres CoronelImanol CorredoiraAnthony CorreiaGloria CortiGiuseppe CostantinoClaudiu-Mihai CotirlanJozie Cottee MeldrumBenjamin CouturierDaniel Charles CraikNicolas CrepetMelissa Maria Cruz TorresMario Alberto Cubero CamposEsteban Curras RiveraRobert CurrieCesar Luiz da SilvaXinchen DaiJeremy DalsenoCarmelo d'AmbrosioGabriella DarzeAlexander DavidsonOscar de Aguiar FranciscoCamilla de AngelisFederico de BenedettiJan de BoerKristof de BruynStefano de CapuaMichel de CianUlisses de Freitas Carneiro da GracaFabio de GregorioErika de LuciaJussara de MirandaLeandro de PaulaAlessandro de RobertisElena de SantisMarilisa de SerioPatrizia de SimoneFabio de VellisJacco de VriesFrancesco DebernardisDaniel DecampSam Michael DekkersLuigi del BuonoBasile Demaire-LepapeJianqiao DengOlivier DeschampsFrancesco DettoriBiplab DeyPasquale Di NezzaShuchong DingYiyang DingLucas DittmannJurgen Francis DiverchyAleksandrina DochevaAlex Patrick DohenyChenzhi DongFrancesca DordeiJavier Dorta MorenoAlberto dos ReisJeferson dos Santos OliveiraAndrew Jay DowlingLea Marie Sophie DreyfusWeisong DuanPiotr Jakub DudaLaurent DufourViacheslav DukPaolo DuranteMaciej DurasJohn Matthew DurhamKira DuweAgnieszka DziurdaSajan EasoEllinor EcksteinUlrik EgedeStephan EisenhardtEnoch EjopuLars EklundMohamed ElashriDaniel Guillermo Elizondo BlancoJan Hendrik EllbrachtScott ElyAlexandru EneTimothy EvansFederica FabianoSaba FaghihLucas FalcaoBo FangRiccardo FantechiLisa FantiniMaria FariaKeira Gwyn FarmerFloris Patrick Jan FassinDavide FazziniLukasz Jerzy FelkowskiChencheng FengMingjie FengAlvaro Fernandez CasaniMiguel Fernandez GomezBrais Fernandez RodinoJac Rafael Fernandez-JohnAlex Daniel FernezFabio FerrariFernando Ferreira RodriguesRosa Anna FiniRenato FiorenzaMassimiliano FioriniMiroslaw FirlejDillon Scott FitzgeraldConor FitzpatrickTomasz FiutowskiFrederic FleuretAlex FominMarianna FontanaMarcos Fontes VazLucas Arthur ForemanRoger FortyDaniel Foulds-HoltVinicius Franco LimaManuel Franco SevillaMarkus FrankEdoardo FranzosoGiulia FrauChristoph FreiDavid Anthony FridayJinlin FuYisheng FuQuentin FühringTommaso FulghesuMatteo FulghieriGiuliana GalatiMaria Domenica GalatiAbraham Gallas TorreiraDomenico GalliSilvia GambettaMiriam GandelmanPaolo GandiniBilal Ahmad GanieHan GaoRui GaoTian-Qi GaoYang GaoYuanning GaoYuxi GaoLuis Miguel Garcia MartinPaula Garcia MorenoJulián García PardiñasParker Taittinger GardnerLluis GarridoClara GasparArsenii GavrikovJoseph GeorgeEvelina GersabeckMarco GersabeckTimothy GershonSimon GhizzoZahra GhorbanimoghaddamFotis Ioannis GiasemisValerie GibsonHenryk Karol GiemzaAlexander Leon GilmanMatteo GiovannettiAlessandra GioventùLucas George GirardeyMaciej Artur GizaFabian Christoph GlaserVladimir GligorovAlfredo GliotiCarla GöbelLarysa Golinka-BezshyykoElisabet GolobardesAndrey GolutvinSergio Gomez FernandezAndres Mauricio Gomez MonguiWojciech GomulkaFernanda Goncalves AbrantesIsadora Gonçales VazMateusz GoncerzGuanghua GongShaokun GongJames Andrew GoodingClaudio GottiEkaterina GovorkovaJascha Peter GrabowskiLuis Alberto Granado CardosoRaul Grande QuartieriEugeni GraugésElena GraveriniLuke GrazetteGiacomo GrazianiAlexandru Tudor GrecuNathan Allen GrieserLucia GrilloChenxi GuMarco GuariseLaetitia GuerryManuel GuittiereAbdul-Kerim GuseinovYury GuzThierry GysKai Sebastian HabermannThomas HadavizadehChristos HadjivasiliouGuido HaefeliChristophe HaenSamuel James HakenGeorge HallettPhoebe Meredith HamiltonQundong HanShuyu HanXiaoxue HanStephanie Hansmann-MenzemerNeville HarnewThomas James HarrisLuca HartmanMarie HartmannSabin HashmiJibo HeNathan Barry HeatleyAndreea-Irina HedesFrederic HemmerConor HendersonRaoul HendersonRiley Dylan Leslie HendersonArthur Marius HennequinKarol HennessyAdrien HenrotJames Daniel HerdPaula Herrero GasconJohannes HeuelAnna-Maria HeynAdlène HicheurGuillermo Hijano MendizabalJoshua Ethan HorswillRuiwen HouYingrui HouDylan Cameron HoustonNed Francis HowarthWenhua HuXiaofan HuWouter HulsbergenRoss John HunterDavid HutchcroftMarek IdzikPhilip IltenAxel IohnerSarunas JaceviciusHendrik JageSergio Javier Jaimes EllesSune JakobsenTomas JakoubekEddy JansAbolhassan JawaheryChanka JayaweeraAlexander Michael JelavicVukan JevticZekun JiaEmily Kaiyin JiangXiaojie JiangYi JiangYuyang JiangEsteban Jimenez MoyaNicholas JindalMalcolm JohnAllen Cris John Rubesh RajanDaniel JohnsonChristopher JonesSalil JoshiBeat JostJuan Jose Juan CastellaNathan JurikIzabela JuszczakKamila Karina KalecinskaDimitrios KaminarisSergii KandybeiMichael James KaneYouen KangChandiprasad KarAnni KauniskangasJacob William KautzMichal Krzysztof KazaneckiFloris KeizerMatthew KenzieTjeerd KetelBasem KhanjiSergei KholodenkoValerii KholoimovGaelle KhreichFatma Zulal KirazThomas KirnVeronica Soelund KirsebomNico KleijneAlina KleimenovaDenys KlekotsKonrad KlimaszewskiMateusz Rafal KmiecTobias Krischan KnospeRuben KolbSerhii KoliievLars KolkAnatoly KonoplyannikovPawel KopciewiczPatrick KoppenburgAlexander KorchinIgor KostiukOleksander KotSofia KotriakhovaElizabeth Marie KowalczykOleg KravcovMichal KrepsWojciech KrupaWojciech KrzemienOleksandr KshyvanskyiSebastian Antoni KubisMarcin KucharczykAndrzej KupscAnna KurzinaVolodymyr KushnirBogdan KutsenkoJakub KvapilIgor KyryllinDaniel LacarrerePaloma Laguarta GonzalezAdriano LaiAndrea LampisDavide LancieriniClara Landesa GomezGaia LanfranchiChristoph LangenbruchThomas LathamFederico LazzariCristina LazzeroniRenaud Le GacHo Sang LeeRegis LefèvreMarion LehurauxClotilde LemettaisEdgar Lemos CidOlivier LeroyTadeusz LesiakEzra Douglas LesserBlake LeveringtonAnfeng LiChen LiChing-Hua LiHengne LiJiuzhao LiKechen LiLanxing LiLonghao LiPeilian LiPei-Rong LiQinze LiTiange LiTianqi LiWanxia LiYanru LiYiming LiYujie LiZifan LiZhengchen LianQiming LiangXixin LiangZhihua LiangSimone LibralonAlisha LightbodyJiazhao LinShaoze LinTai-Hua LinRolf LindnerHenry James LintonRoman LitvinovDuanqing LiuFrank Xiangyu LiuGuoming LiuKai LiuShuaiyi LiuWeijie LiuXueyin LiuYiming LiuYing LiuYiwei LiuGustavo Alejandro Loachamin OrdonezIsaac Graciano LoboAniol Lobo SalviaAngelo LoiThomas LongFelipe Cesario Laterza LopesJose LopesAlbert Lopez HuertasCristina Lopez IribarnegarayQiuchan LuChiara LucarelliDonatella LucchesiMiriam Lucio MartinezYiheng LuoAnna LupatoMichael LupbergerEleonora LuppiKate LynchJiayi LyuShuotian LyuXiao-Rui LyuHeng MaSerena MaccoliniFrederic MachefertFlorin MaciucBridget MackInnes MackayLauren Grace MackeyLakshan Ram Madhan MohanMarcus Jonathan MaduraiDaniel MagdalinskiJakub Jacek MalczewskiSneha MaldeLorenzo MalentaccaGiulia MancaChiara MancusoRafel Manera EscaleroAbdussamad MangalasseriFederico ManganellaRitwik Rajesh MangrulkarDaniele ManuzziShenghan MaoDaniele MarangottoJean François MarchandRadoslav MarchevskiUmberto MarconiLeo MaresoEdoardo MarianiSaverio MarianiCarla Marin BenitoJörg MarksAlexander Mclean MarshallLucas MartelGabriele MartelliGiuseppe MartellottiLoris MartinazzoliMaurizio MartinelliCamila Belen MartinezAlberto Martinez ArmasDaniel Guillermo Martinez GomezDiego Martinez SantosFernando Martinez VidalAlexia Martorell GranollersAndré MassafferriRosen MatevAbhijit MathadClara MatteuzziKara Renee MattioliLuke Davis MatznerAndrea MauriEmilie MauriceJoan MauricioPierre Paul Louis MayencourtJose Mazorra de CosMichal MazurekDavid Mazzanti TaranconMichael MccannNiall Thomas MchughAndrew McnabRonan McnultyBrian MeadowsSacha Emile R MedaerDmytro MelnychukDiego Mendoza GranadaPablo Eduardo Menendez Valdes PerezFanjie MengMarcel MerkAndrea MerliLucas Meyer GarciaDexing MiaoHan MiaoSamuel MicoMikhail MikhasenkoDiego Alejandro 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• Organismes : Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire Leprince-Ringuet Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Laboratoire Leprince-Ringuet Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie

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Résumé : The lifetime ratio ${r_τ\equivτ_{Ω_b^-}/τ_{Ξ_b^-}}$ between the ${Ω_b^-}$ and ${Ξ_b^-}$ baryons is measured using a sample of $pp$ collision data corresponding to an integrated luminosity of 6 fb$^{-1}$ and collected by the LHCb experiment during LHC Run 2 (2015$-$2018). The ratio $r_τ$ is measured in two sets of decays modes, ${ {(Ω_b^-,Ξ_b^-)\to(Ω_c^0π^-,Ξ_c^0π^-)}}$ and ${(Ω_b^-,Ξ_b^-)\to(J/ψΩ^-, J/ψΞ^-)}$, with ${(Ω_c^0,Ξ_c^0)\to pK^-K^-π^+}$, ${(Ω^-,Ξ^-)\to(Λ^0 K^-,Λ^0π^-)}$, ${Λ^0\to pπ^-}$ and $J/ψ\toμ^+μ^-$. The measured $r_τ$ values are averaged and combined with Run 1 (2011$-$2012) measurements in the same decay modes to obtain ${r_τ = 1.109\pm0.055\pm0.010}$. Multiplying by the known ${Ξ_b^-}$ lifetime results in the ${Ω_b^-}$ lifetime ${τ_{Ω_b^-} = 1.751\pm0.089\pm0.022~{\rm ps}}$, where the uncertainties are statistical and systematic. This measurement improves on the precision of the $Ω_b^-$ lifetime by about a factor of two over the previous world average. The value of $r_τ$ is in agreement with the most recent theoretical predictions from the heavy quark expansion framework.

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Source

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 06/10/2026
• Auteurs : Dana Ali Hassan AbdallahIbrahim Jaser AbualrobShreyasi AcharyaKshitij AgarwalGianluca Aglieri RinellaLuca AgliettaNeelima AgrawalZubayer AhammedShakeel AhmadZulkaida AkbarValentina AkishinaMohammad Al-TuranyBruno AlessandroAbdul Rahman AlfarasyiJose Ruben Alfaro MolinaBushra AliAndrea AliciJohan AlmeGiacomo AloccoTorsten AltIgor AltsybeevCristian AndreiNicodemos AndreouAnton AndronicMassimo AngelettiVenelin AnguelovFederico AntinoriPietro AntonioliNicole ApadulaHarald AppelshaeuserSilvia ArcelliRoberta ArnaldiIonut Cristian ArseneMesut ArslandokMuhammad Uzair AslamAndre AugustinusRalf Peter AverbeckMohd Danish AzmiByungyun KongHitoshi BabaAkash Raj John BabuAngela BadalaJoonsuk BaeYunseul BaeYongwook BaekXiaozhi BaiRaphaelle Marie BailhacheYoshini BailungRenu BalaAlberto BaldisseriBartosz BalisShubham BangaliaKoushik BaraiVeronika BarbasovaFrancesco BarileLuca BarioglioMaria BarlouBanajit BarmanGergely Gabor BarnafoldiLee Stuart BarnbyEmilie Martine BarreauValerie Ramillien BarretLeonardo Barreto de Oliveira CamposKlaus BarthEsther BartschNicole BastidGuillaume BatigneDaniel BattistiniBoris BatyunyaLuca BaudinoDibakar BauriJose Luis Bazo AlbaIan Gardner BeardenDebadatta BeheraSwadhin BeheraMaria Alejandra Calmon BehlingIouri BelikovValerio Di BellaFrancesca BelliniRene BellwiedLucina Gabriela Espinoza BeltranYael Antonio Vasquez BeltranGyula BencediOussama BenchikhiAdel BensaoulaStefania Maria BeoleAnastasia BerdnikovaLuisa BergmannLorenzo BernardinisLatchezar BetevPartha Pratim BhaduriTushar BhallaAnju BhasinBuddhadeb BhattacharjeeLivio BianchiJaroslav BielcikJana BielcikovaAnte BilandzicAnna BinoyGabor BiroSaikat BiswasMihail Bogdan BlidaruNora BluhmeChristoph BlumeFriederike BockLaszlo BoldizsarMarek BombaraPeter Matthew BondGermano BonomiHerve BorelAlexander BorissovAndres Gerardo Borquez CarcamoElena BottaNaseem BouchharYoussef El Mard BouzianiDiana Catalina BrandiburLars BratrudPeter Braun-MunzingerMarco BregantMichal BrozGiuseppe Eugenio 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• Organismes : Institut de Physique des 2 Infinis de Lyon Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de physique subatomique et des technologies associées Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Physique des 2 Infinis de Lyon Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut Pluridisciplinaire Hubert Curien Institut Pluridisciplinaire Hubert Curien Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique de Clermont Institut de Physique des 2 Infinis de Lyon Institut Pluridisciplinaire Hubert Curien Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Physique des 2 Infinis de Lyon Institut Pluridisciplinaire Hubert Curien Laboratoire de physique subatomique et des technologies associées Laboratoire de physique subatomique et des technologies associées Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Subatomique et de Cosmologie Laboratoire de Physique de Clermont Institut de Physique des 2 Infinis de Lyon Institut de Recherches sur les lois Fondamentales de l'Univers Institut de Physique des 2 Infinis de Lyon Laboratoire de Physique de Clermont

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Résumé : A measurement of the correlation between the splitting angle $θ_{\rm g}$ and the momentum-sharing fraction $z_{\rm g}$ of the first hard splitting in a parton shower in pp collisions and 0$-$10% central Pb$-$Pb collisions at $\sqrt{s_{\rm NN}}$ = 5 TeV with the ALICE detector is reported. Charged-particle jets are reconstructed using the anti-$k_{\rm T}$ algorithm with a jet resolution parameter $R$ = 0.2, in the transverse-momentum range $60 \leq p_{\rm T,ch\;jet} < 80$ GeV/$c$. The Soft Drop grooming algorithm is used to identify the first splitting in the parton shower. Jets observed in Pb$-$Pb collisions are narrower than in pp collisions. This effect is more pronounced for balanced than for unbalanced jets. No significant modification of the momentum-sharing fraction is observed for jets with small opening angles. In contrast, there is a hint that jets with a large opening angle may be less balanced in transverse momentum in Pb$-$Pb collisions compared to pp collisions. The correlations between $θ_{\rm g}$ and $z_{\rm g}$ are well described in pp collisions by PYTHIA 8 and POWHEG while HERWIG shows too few jets with large opening angle. In Pb$-$Pb collisions the measurement is compared to a variety of models. The measurement is insensitive to the different implementations of medium response. Inclusion of elastic scatterings, as implemented in the HYBRID model is preferred to describe the unbalanced jets with large $θ_{\rm g}$ in Pb$-$Pb collisions. The balanced jets, however, are less sensitive to elastic scatterings.

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Source

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• Type de publi. : Pré-publication, Document de travail
• Date de publi. : 06/10/2026
• Auteurs : Roel AaijMohammed AbdelfatahAhmed Sameh Wagih AbdelmottelebCarlos Abellan BetetaFernando Jesus AbudinénThomas AckernleyAyomide Matthew AdefisoyeBernardo AdevaMarco AdinolfiPatrik Harri AdlarsonChristina AgapopoulouChristine Angela AidalaSimon AkarKazuyoshi AkibaHussain Hassan A Al SalehPietro AlbicoccoJohannes AlbrechtRamunas AleksiejunasFederico AlessioPaula Alvarez CartelleSandra AmatoJake Lewis AmeyYasmine AmhisZachariah Benjamin AmosLiupan AnLucio AnderliniPasquale AndreolaMirco AndreottiSergio Andres EstradaAlessia AnelliDong AoCarolina ArataFlavio ArchilliZaratsyan AregMatteo ArgentonSergio Arguedas CuendisLisa ArnoneMarina ArtusoElie AslanidesRita Ataíde da SilvaMichele AtzeniBenjamin AudurierJuliette AuthierDavid BacherIrene Bachiller PereaSebastian BachmannMarie BachmayerJohn BackMaoze BaiZiyu BaiVladislav BalaguraAnna BalboniWander BaldiniZachary BaldwinLuca BalzaniHaoran BaoJuan Baptista de Souza LeiteCarlos Javier Barbero PretelMatteo BarbettiIvanildo Rui BarbosaWilliam David BarkerRoger BarlowMikhail BarnyakovSophie BaronSergey BarsukWilliam BarterJustin BartzSaliha BashirBaasansuren BatsukhPiera BattistaAli BavarcheeAurelio BayAnja BeckMaik BeckerFranco BedeschiIgnacio BediagaNoah Albin BehlingSamuel BelinAlberto BellavistaIvan BelyaevGiovanni BencivenniEli Ben-HaimJulie BerkeyRoland BernetAlessandro BertolinLukas Frederic BertschFederico BettiJosh BexOleg BezshyykoSenjuti BhattacharyaMartin Stefan BiekerNicolo Vladi BiesuzAlice BiolchiniMatthew BirchFionn Caitlin Ros BishopAlexander BitadzeAndrea BizzetiThomas BlakeFrederic BlancJonah Evan BlankSteven BluskJulian Alexander BoelhauveOscar Boente GarciaThomas BoettcherAbhishek BohareCarolina BolognaniRiccardo BonacciAleksandar BordeliusFederica BorgatoSilvia BorghiMartino BorsatoJozef Tomasz BorsukElia BottalicoSonia Amina BouchibaMarcelo BovillThemistocles BowcockAlexandre BoyerConcezio BozziJames Daniel BrandenburgAlexandre Brea RodriguezNils BreerChristopher BreitfeldJolanta BrodzickaJames David BrownEmma BuchananMarta Burgos MarcosChristopher BurrClarissa ButiJordy Sebastiaan ButterJan BuytaertWiktor ByczynskiSandro CadedduHao CaiYichao CaiYuman CaiAlois CailletRoberto CalabreseLukas CaleficeMarta CalviMiriam Calvo GomezPatricia Camargo MagalhaesJose Ivan Cambon BouzasPierluigi CampanaAndrea Fulvio CampomagnaniAlexandre CamposAngel Fernando Campoverde QuezadaYuhang CaoSimone CapelliMarco CaporaleLorenzo CapriottiRonald Gerardo Caravaca-MoraAngelo CarboneLidia Carcedo SalgadoRoberta CardinaleAlessandro CardiniPaolo CarnitiLeon David CarusAdrian Casais VidalRowina CasparyGianluigi CasseMarco CattaneoGiovanni CavalleroViola CavalliniSara CelaniIrene CelestinoSara CesareAbbie Jane ChadwickMatthew CharlesPhilippe CharpentierEvridki ChatzianagnostouRacha CheaibMaximilien ChefdevilleChen ChenJou-An ChenShanzhen ChenZewen ChenAlex Chen HuMostafa CherifSerhii ChernyshenkoXenofon ChiotopoulosGleb ChizhikVeronika ChobanovaAlec ChristakakisMarcin ChrzaszczYanbo 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• Organismes : Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Institut de Recherches sur les lois Fondamentales de l'Univers Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire d'Annecy de Physique des Particules Laboratoire Leprince-Ringuet Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Laboratoire de Physique de Clermont Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique de Clermont Laboratoire Leprince-Ringuet Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Institut de Recherches sur les lois Fondamentales de l'Univers Laboratoire de Physique des 2 Infinis Irène Joliot-Curie

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Résumé : As the essential building blocks of visible matter, hadrons have traditionally been classified by the quark model as mesons composed of quark-antiquark pairs and baryons built from three valence quarks. Yet, this classical picture does not account for the intricate chiral dynamics of the strong force and the emergence of exotic multi-quark hadrons. While experimental evidence for such unconventional dynamics has surfaced in the charm sector, the open-beauty system remains the long-sought frontier for testing the universality of these mechanisms. Here the observation of a new resonance in the beauty-strange sector with a global significance exceeding seven standard deviations is reported using proton-proton collision data recorded by the Large Hadron Collider beauty (LHCb) experiment at the European Organization for Nuclear Research (CERN). It exhibits a narrow natural width and a substantial mass deficit compared to the conventional quark model predictions. This result marks the first observation of a nonconventional single-beauty hadron, providing crucial insights into the chiral dynamics of the strong interaction and heavy-quark spin symmetry in the exotic domain.

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