Professeur des universités en sciences de gestion
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Identification of several eating habits that mediate the association between eating behaviors and the risk of obesity
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Estelle AymesGabrielle LisembardJean DallongevilleJulien RousseauxMarie‐pierre DumontPhilippe AmouyelMonique RomonAline Meirhaeghe
Fiche détaillée
Identification of several eating habits that mediate the association between eating behaviors and the risk of obesity
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Estelle AymesGabrielle LisembardJean DallongevilleJulien RousseauxMarie‐pierre DumontPhilippe AmouyelMonique RomonAline Meirhaeghe
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Organismes :
Institut National de la Santé et de la Recherche Médicale
Facteurs de Risque et Déterminants Moléculaires des Maladies liées au Vieillissement - U 1167
- Publié dans Obesity Science & Practice le 27/07/2023
Source
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Formation of N2(B, v′) levels in N2, N2/Ar and N2/He reduced pressure late afterglows
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Valentin FerrerJ P GardouAndré RicardJean-Philippe SarretteF. Marchal
Fiche détaillée
Formation of N2(B, v′) levels in N2, N2/Ar and N2/He reduced pressure late afterglows
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Valentin FerrerJ P GardouAndré RicardJean-Philippe SarretteF. Marchal
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Organismes :
Plasmas Réactifs Hors Equilibre
Plasmas Réactifs Hors Equilibre
Institut Universitaire de Technologie - Paul Sabatier
Plasmas Réactifs Hors Equilibre
Plasmas Réactifs Hors Equilibre
Plasmas Réactifs Hors Equilibre
- Publié dans The European Physical Journal D : Atomic, molecular, optical and plasma physics le 28/10/2020
Fichiers liés :
10053_2022_512_Author.pdf
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Undernutrition, overweight and obesity prevalences among community-dwelling elderly in Africa-a systematic review
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Gustave MabiamaThierno MillimonoDieudonné AdiogoFarid BoumedienePierre-Marie PreuxJean-Claude DesportPhilippe FayemendyPierre Jésus
Fiche détaillée
Undernutrition, overweight and obesity prevalences among community-dwelling elderly in Africa-a systematic review
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Gustave MabiamaThierno MillimonoDieudonné AdiogoFarid BoumedienePierre-Marie PreuxJean-Claude DesportPhilippe FayemendyPierre Jésus
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Organismes :
Université de Douala = University of Douala
Epidémiologie des Maladies Chroniques en zone tropicale
Epidémiologie des Maladies Chroniques en zone tropicale
Microbiology, Immunology-Hematology and Morphologic Sciences Laboratory (LMIHSM)
Epidémiologie des Maladies Chroniques en zone tropicale
Epidémiologie des Maladies Chroniques en zone tropicale
Epidémiologie des Maladies Chroniques en zone tropicale
Nutrition Resources Center CERENUT, Isle
Epidémiologie des Maladies Chroniques en zone tropicale
Nutrition Resources Center CERENUT, Isle
Epidémiologie des Maladies Chroniques en zone tropicale
Nutrition Resources Center CERENUT, Isle
- Publié dans Clinical nutrition open science/Clin Nutr Open Sci le 30/08/2022
Source
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Immunologically active phenotype by gene expression profiling is associated with clinical benefit from PD-1/PD-L1 inhibitors in real-world head and neck and lung cancer patients
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Jean-Philippe FoyAndy KarabajakianSandra Ortiz-CuaranMaxime BoussageonLucas MichonJebrane BouaoudDorssafe FekiriMarie RobertKim-Arthur BaffertChristophe CauxGeneviève HervéPauline QuilhotValéry AttignonAngélique GirodAndré ChaineMourad BenassarouPhilippe ZrounbaFrançois GhiringhelliSylvie LantuejoulCarole CrozesIsabelle BrochériouMaurice PérolJérôme FayetteChloé BertolusPierre Saintigny
Fiche détaillée
Immunologically active phenotype by gene expression profiling is associated with clinical benefit from PD-1/PD-L1 inhibitors in real-world head and neck and lung cancer patients
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Jean-Philippe FoyAndy KarabajakianSandra Ortiz-CuaranMaxime BoussageonLucas MichonJebrane BouaoudDorssafe FekiriMarie RobertKim-Arthur BaffertChristophe CauxGeneviève HervéPauline QuilhotValéry AttignonAngélique GirodAndré ChaineMourad BenassarouPhilippe ZrounbaFrançois GhiringhelliSylvie LantuejoulCarole CrozesIsabelle BrochériouMaurice PérolJérôme FayetteChloé BertolusPierre Saintigny
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Organismes :
Centre de Recherche en Cancérologie de Lyon
Centre de Recherche en Cancérologie de Lyon
Centre de Recherche en Cancérologie de Lyon
Plateforme anatomopathologie recherche Lyon-Est
Centre Léon Bérard [Lyon]
Centre de Recherche en Cancérologie de Lyon
- Publié dans European Journal of Cancer le 22/10/2020
Source
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Oncological Outcomes of Delayed Nephrectomy After Optimal Response to Immune Checkpoint Inhibitors for Metastatic Renal Cell Carcinoma
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Géraldine PignotAntoine Thiery-VuilleminLaurence AlbigèsJochen WalzHervé LangLoïc BalssaBastien ParierLionnel GeoffroisKarim BensalahFriederike SchlürmannSylvain LadoirePierre BigotDelphine BorchielliniOphélie CassutoConstance ThibaultAlexandre IngelsVéronique SaldanaGuilhem RoubaudJean-Christophe BernhardGwenaelle GravisPhilippe Barthélémy
Fiche détaillée
Oncological Outcomes of Delayed Nephrectomy After Optimal Response to Immune Checkpoint Inhibitors for Metastatic Renal Cell Carcinoma
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Géraldine PignotAntoine Thiery-VuilleminLaurence AlbigèsJochen WalzHervé LangLoïc BalssaBastien ParierLionnel GeoffroisKarim BensalahFriederike SchlürmannSylvain LadoirePierre BigotDelphine BorchielliniOphélie CassutoConstance ThibaultAlexandre IngelsVéronique SaldanaGuilhem RoubaudJean-Christophe BernhardGwenaelle GravisPhilippe Barthélémy
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Organismes :
Laboratoire Traitement du Signal et de l'Image
Centre de Recherche en Cancérologie de Marseille
- Publié dans European Urology Oncology le 02/11/2020
Source
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Is monkeypox virus transmissible by breastfeeding?
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Philippe Van de PerreJean-Pierre MolesNigel Rollins
Fiche détaillée
Is monkeypox virus transmissible by breastfeeding?
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Philippe Van de PerreJean-Pierre MolesNigel Rollins
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Organismes :
Pathogenesis and Control of Chronic and Emerging Infections
Pathogenesis and Control of Chronic and Emerging Infections
- Publié dans Pediatric Allergy and Immunology le 02/11/2020
Source
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Advances in human intracranial electroencephalography research, guidelines and good practices
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Manuel MercierAnne-Sophie DubarryFrançois TadelPietro AvanziniNikolai AxmacherDillan CellierMaria Del VecchioLiberty HamiltonDora HermesMichael KahanaRobert KnightAnaïs LlorensPierre MégevandLucia MelloniKai MillerVitória PiaiAina PuceNick RamseyCaspar SchwiedrzikSydney SmithArjen StolkNicole SwannMariska VansteenselBradley VoytekLiang WangJean-Philippe LachauxRobert Oostenveld
Fiche détaillée
Advances in human intracranial electroencephalography research, guidelines and good practices
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Manuel MercierAnne-Sophie DubarryFrançois TadelPietro AvanziniNikolai AxmacherDillan CellierMaria Del VecchioLiberty HamiltonDora HermesMichael KahanaRobert KnightAnaïs LlorensPierre MégevandLucia MelloniKai MillerVitória PiaiAina PuceNick RamseyCaspar SchwiedrzikSydney SmithArjen StolkNicole SwannMariska VansteenselBradley VoytekLiang WangJean-Philippe LachauxRobert Oostenveld
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Organismes :
Institut de Neurosciences des Systèmes
Laboratoire Parole et Langage
University of Southern California
National Research Council of Italy | Consiglio Nazionale delle Ricerche
Ruhr University Bochum = Ruhr-Universität Bochum [Bochum]
Beijing Normal University
University of California [San Diego]
National Research Council of Italy | Consiglio Nazionale delle Ricerche
University of Texas at Austin [Austin]
Mayo Clinic [Rochester]
University of Pennsylvania [Philadelphia]
University of California [Berkeley]
University of California [Berkeley]
Université de Genève = University of Geneva
Max Planck Institute for Empirical Aesthetics [Frankfurt am Main]
New York University School of Medicine
Mayo Clinic [Rochester]
Radboud University [Nijmegen]
Indiana University [Bloomington]
University Medical Center [Utrecht]
University Medical Center Göttingen
German Primate Center - Deutsches Primatenzentrum - Leibniz Insitute for Primate Research [Göttingen]
University of California [San Diego]
Radboud University [Nijmegen]
Dartmouth College [Hanover]
University of Oregon [Eugene]
University Medical Center [Utrecht]
University of California [San Diego]
Institute of Psychology [Beijing]
Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center
Radboud University [Nijmegen]
Karolinska Institutet = Karolinska Institute [Stockholm]
- Publié dans NeuroImage le 01/11/2020
Résumé : Since the second-half of the twentieth century, intracranial electroencephalography (iEEG), including both electrocorticography (ECoG) and stereo-electroencephalography (sEEG), has provided an intimate view into the human brain. At the interface between fundamental research and the clinic, iEEG provides both high temporal resolution and high spatial specificity but comes with constraints, such as the individual's tailored sparsity of electrode sampling. Over the years, researchers in neuroscience developed their practices to make the most of the iEEG approach. Here we offer a critical review of iEEG research practices in a didactic framework for newcomers, as well addressing issues encountered by proficient researchers. The scope is threefold: (i) review common practices in iEEG research, (ii) suggest potential guidelines for working with iEEG data and answer frequently asked questions based on the most widespread practices, and (iii) based on current neurophysiological knowledge and methodologies, pave the way to good practice standards in iEEG research. The organization of this paper follows the steps of iEEG data processing. The first section contextualizes iEEG data collection. The second section focuses on localization of intracranial electrodes. The third section highlights the main pre-processing steps. The fourth section presents iEEG signal analysis methods. The fifth section discusses statistical approaches. The sixth section draws some unique perspectives on iEEG research. Finally, to ensure a consistent nomenclature throughout the manuscript and to align with other guidelines, e.g., Brain Imaging Data Structure (BIDS) and the OHBM Committee on Best Practices in Data Analysis and Sharing (COBIDAS), we provide a glossary to disambiguate terms related to iEEG research.
Fichiers liés :
main.pdf
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Five-year clinical outcomes using the bioresorbable vascular scaffold: Insights from the FRANCE ABSORB registry
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Quentin LandolffThierry LefèvreJean FajadetJoel SainsousThibault LhermusierSimon ElhadadFrançois TarraganoSylvain RancSaïd GhostineGuillaume CaylaFrédéric MarcoPhilippe GarotLuc MaillardPascal MotreffNicolas DelarcheAxel de LabriolleMichel PansieriJean-François MorellePierre CazauxMarc Eric MoulichonPatrick ChopatD AngoulvantVincent BatailleHervé Le BretonRené Koning
Fiche détaillée
Five-year clinical outcomes using the bioresorbable vascular scaffold: Insights from the FRANCE ABSORB registry
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Quentin LandolffThierry LefèvreJean FajadetJoel SainsousThibault LhermusierSimon ElhadadFrançois TarraganoSylvain RancSaïd GhostineGuillaume CaylaFrédéric MarcoPhilippe GarotLuc MaillardPascal MotreffNicolas DelarcheAxel de LabriolleMichel PansieriJean-François MorellePierre CazauxMarc Eric MoulichonPatrick ChopatD AngoulvantVincent BatailleHervé Le BretonRené Koning
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Organismes :
Clinique Saint-Hilaire [Rouen]
Hôpital Privé Jacques Cartier [Massy]
Clinique Pasteur [Toulouse]
Clinique Rhône Durance - ELSAN
Centre Hospitalier Universitaire de Toulouse
Centre Hospitalier de Marne-la-Vallée [Jossigny]
Hôpital Américain de Paris
Centre hospitalier Saint Joseph - Saint Luc [Lyon]
Hôpital Marie-Lannelongue
Centre Hospitalier Universitaire de Nîmes
Capio Polyclinique du Parc
Centre Hospitalier Privé Claude Galien - Ramsay Santé
Pelvi-Perineal Surgery and Rehabilitation Department, Private Medical Centre "l'Avancée-Clinique Axium", Aix en Provence, France.
Service Chirurgie Cardio-Vasculaire [CHU Clermont-Ferrand]
Centre hospitalier de Pau
Clinique du Pont de Chaume - ELSAN
Centre Hospitalier Henri Duffaut [Avignon]
Hôpital Privé Saint-Martin [Caen]
Groupe Hospitalier Bretagne Sud
Centre Hospitalier Saint Jean de Perpignan
Centre hospitalier territorial Gaston-Bourret [Dumbea, Nouvelle-Calédonie]
Centre Hospitalier Régional Universitaire de Tours
Université Toulouse III Paul Sabatier - Faculté de médecine Purpan
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Clinique Saint-Hilaire [Rouen]
- Publié dans Archives of cardiovascular diseases le 30/10/2020
Résumé : Background: randomized trials comparing the first-generation absorb bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, CA, USA) with a drug-eluting stent showed a moderate but significant increase in the rate of 3-year major adverse cardiac events and scaffold thrombosis, followed by a decrease in adverse events after 3 years. Aim: the objective of this study was to assess the 5-year outcomes of patients treated with at least one absorb BVS and included in the FRANCE ABSORB registry. Methods: all patients treated in France with an absorb BVS were prospectively included in a large nationwide multicentre registry. The primary efficacy outcome was the occurrence of 5-year major adverse cardiac events. Secondary efficacy outcomes were the rates of 5-year target vessel revascularization and definite/probable scaffold thrombosis. Results: between September 2014 and April 2016, 2,070 patients were included in 86 centres (mean age 55±11 years; 80% men; 49% with acute coronary syndrome). The rates of 1-, 3- and 5-year major adverse cardiac events were 3.9%, 9.4% and 12.1%, respectively (including cardiac death in 2.5% and target vessel revascularization in 10.4%). By multivariable analysis, diabetes, oral anticoagulation, the use of multiple Absorb BVSs and the use of a 2.5mm diameter absorb BVS were associated with 5-year major adverse cardiac events. The rates of 1-, 3- and 5-year definite/probable scaffold thrombosis were 1.5%, 3.1% and 3.6%, respectively. By multivariable analysis, older age, diabetes, anticoagulation at discharge and the use of a 2.5mm diameter absorb BVS were associated with 5-year scaffold thrombosis. Conclusions: absorb BVS implantation was associated with low rates of 1-year major adverse cardiac events, which increased significantly at 3-year follow-up. There was a clear decrease in the rates of scaffold thrombosis and major adverse cardiac events after 3 years.
Source
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Sotrovimab to Prevent Severe COVID-19 in High-Risk Patients Infected with Omicron BA.2
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Guillaume Martin-BlondelAnne-Geneviève MarcelinCathia SouliéSofia KaisaridiClovis Lusivika-NzingaCéline DorivalLaura NaillerAnaïs BostonCléa MelenotteAndré CabiéChristophe ChoquetFrançois CoustillèresJean-Philippe MartellosioGéraldine GaubeAlbert Trinh-DucAnne-Marie RonchettiValérie PourcherMarie ChauveauKarine LacombeNathan Peiffer-SmadjaPierre HoussetAurore PerrotGilles PialouxAurélie MartinVincent DubéeMathilde DevauxJérôme FreyCharles CazanaveRoland S LiblauFabrice CarratYouri Yordanov
Fiche détaillée
Sotrovimab to Prevent Severe COVID-19 in High-Risk Patients Infected with Omicron BA.2
- Type de publi. : Article dans une revue
- Date de publi. : 01/10/2022
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Auteurs :
Guillaume Martin-BlondelAnne-Geneviève MarcelinCathia SouliéSofia KaisaridiClovis Lusivika-NzingaCéline DorivalLaura NaillerAnaïs BostonCléa MelenotteAndré CabiéChristophe ChoquetFrançois CoustillèresJean-Philippe MartellosioGéraldine GaubeAlbert Trinh-DucAnne-Marie RonchettiValérie PourcherMarie ChauveauKarine LacombeNathan Peiffer-SmadjaPierre HoussetAurore PerrotGilles PialouxAurélie MartinVincent DubéeMathilde DevauxJérôme FreyCharles CazanaveRoland S LiblauFabrice CarratYouri Yordanov
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Organismes :
Service Maladies infectieuses et tropicales [CHU Toulouse]
Institut Toulousain des Maladies Infectieuses et Inflammatoires
Institut Pierre Louis d'Epidémiologie et de Santé Publique
Institut Pierre Louis d'Epidémiologie et de Santé Publique
AP-HP - Hôpital de la Pitié Salpêtrière
Institut Pierre Louis d'Epidémiologie et de Santé Publique
Institut Pierre Louis d'Epidémiologie et de Santé Publique
Institut Pierre Louis d'Epidémiologie et de Santé Publique
ANRS France Recherche Nord & sud Sida-hiv hépatites
ANRS France Recherche Nord & sud Sida-hiv hépatites
AP-HP - Hôpital Necker - Enfants Malades
Centre d'Investigation Clinique Antilles-Guyane
Pathogenesis and Control of Chronic and Emerging Infections
AP-HP - Hôpital Bichat - Claude Bernard [Paris]
Centre Hospitalier Régional Universitaire de Tours
Centre hospitalier universitaire de Poitiers = Poitiers University Hospital
Service Maladies infectieuses et tropicales [CHU Toulouse]
Centre Hospitalier Agen-Nérac
Centre Hospitalier Sud Francilien - Centre Hospitalier d'Evry
AP-HP - Hôpital de la Pitié Salpêtrière
Hôpital Hôtel-Dieu [CHU Nantes]
Centre d’Investigation Clinique de Nantes
Institut Pierre Louis d'Epidémiologie et de Santé Publique
AP-HP - Hôpital Saint-Antoine
Services de Maladies Infectieuses et Tropicales [CHU Bichat]
Centre Hospitalier Sud Francilien - Centre Hospitalier d'Evry
Service Hématologie - IUCT-Oncopole [CHU Toulouse]
AP-HP - Hôpital Tenon
Centre Hospitalier Universitaire de Nîmes
Centre Hospitalier Universitaire d'Angers
Centre Hospitalier Intercommunal de Poissy/Saint-Germain-en-Laye
Centre hospitalier régional de Metz-Thionville
Centre Hospitalier Universitaire de Bordeaux
Microbiologie Fondamentale et Pathogénicité
Institut Toulousain des Maladies Infectieuses et Inflammatoires
Service d'Allergologie et d'Immunologie [CHU Toulouse]
Épidémiologie clinique des maladies virales chroniques [iPLesp]
AP-HP - Hôpital Saint-Antoine
Institut Pierre Louis d'Epidémiologie et de Santé Publique
AP-HP - Hôpital Saint-Antoine
- Publié dans Journal of Infection le 23/10/2020
Résumé : Before the Omicron era, the neutralizing antibody targeting the SARS-CoV2 Spike protein Sotrovimab has been shown to reduce the risk of COVID-19-related hospitalization in patients who are at high risk for progression. We recently showed that early administration of Sotrovimab in Omicron-infected patients with very high-risk for progression was associated with a low rate of COVID-19-related hospitalization within one month after treatment administration (3%), and with no death. However, the dominance of the Omicron sublineage BA.2 led health agencies to suspend Sotrovimab emergency use authorizations because of its lower neutralizing ability in vitro compared to BA.1 sublineage . Clinical efficiency of Sotrovimab to prevent COVID-19 related complications in high-risk patients with mild-to-moderate COVID-19 Omicron BA.2 remains unknown. Our aim was to compare the clinical and virological outcomes of Omicron BA.1 and BA.2-infected patients with mild-to-moderate COVID-19 who received 500 mg of Sotrovimab IV to prevent COVID-19-related complications.
Fichiers liés :
Martin-Blondel et al. - 2022 - Sotrovimab to prevent severe COVID-19 in high-risk.pdf
Source
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AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicenter results from Western France
- Type de publi. : Article dans une revue
- Date de publi. : 29/09/2022
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Auteurs :
Clément DubostJacques TomasiAntoine DucroixKévin PluchonPierre EscrigOlivier FouquetArthur AupartAlain MirzaImen FellahEric BezonChristophe BaufretonJean Marc El AridJean-Christian RousselJean-Philippe VerhoyeThomas Sénage
Fiche détaillée
AORTLANTIC: French registry of aortic valve-sparing root replacement, preliminary multicenter results from Western France
- Type de publi. : Article dans une revue
- Date de publi. : 29/09/2022
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Auteurs :
Clément DubostJacques TomasiAntoine DucroixKévin PluchonPierre EscrigOlivier FouquetArthur AupartAlain MirzaImen FellahEric BezonChristophe BaufretonJean Marc El AridJean-Christian RousselJean-Philippe VerhoyeThomas Sénage
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Organismes :
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital
ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291
Laboratoire Traitement du Signal et de l'Image
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Centre Hospitalier Universitaire d'Angers
Centre Hospitalier Régional Universitaire de Brest
Laboratoire Traitement du Signal et de l'Image
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Centre Hospitalier Universitaire d'Angers
Centre Hospitalier Régional Universitaire de Tours
Nouvelle Clinique de Tours Saint Gatien-Alliance [Tours]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital
ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291
Centre Hospitalier Régional Universitaire de Brest
Centre Hospitalier Universitaire d'Angers
Centre Hospitalier Régional Universitaire de Tours
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital
ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291
Laboratoire Traitement du Signal et de l'Image
Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou]
Centre Hospitalier Universitaire de Nantes = Nantes University Hospital
ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291
- Publié dans Interactive Cardiovascular and Thoracic Surgery le 22/10/2020
Résumé : OBJECTIVES: Aortic root aneurysms often affect younger patients in whom valve-sparing surgery is challenging. Amongst current techniques, aortic valve-sparing root replacement described by Tirone David has shown encouraging results. The AORTLANTIC registry was instituted for a multicentre long-term evaluation of this procedure. The current initial study evaluates the hospital outcomes of the procedure. MATERIAL AND METHOD: This is a retrospective study of patients operated between January 01, 2004, and December 31, 2020, in 6 hospitals in western France. All study data were recorded in the national digital database of the French Society of Cardiac Surgery: EPICARD. RESULTS: 524 consecutive patients with a mean age of 53(15.1) years underwent surgery. 13% (n = 68) patients presented with acute aortic dissection, 16.5% (n = 86) had associated connective tissue pathology and 7.3% (n = 37) had bicuspid aortic valves. Preoperative aortic regurgitation ≥ 2/4 was present in 65.3% (n = 341) of patients. Aortic valvuloplasty was required in 18.6% (n = 95) patients. At discharge, 92.8% (n = 461) patients had no or 1/4 aortic regurgitation. The stroke rate was 1.9% (n = 10). Intra-hospital mortality was 1.9% (n = 10). CONCLUSION: The AORTLANTIC registry includes 6 centers in western France with more than 500 patients. Despite numerous complex cases (acute aortic dissections, bicuspid aortic valves, preoperative aortic regurgitation), aortic valve-sparing root replacement has a low intra-hospital mortality. The initial encouraging results of this multicentre study warrant further long-term evaluation by future studies. CLINICAL REGISTRATION NUMBER: Nov 2021: This registry was approved by an ethics committee mandated by the CNIL (Commission Nationale de l’Informatique et des Libertés) to approve scientific projects of the Nantes Hospital Centre.
Fichiers liés :
ivac240.pdf
Source