Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 16/02/2021
• Auteurs : Anne-Laure Larroque-LombardÉtienne ChatelutJean-Pierre DelordDiane-Charlotte ImbsPhilippe RochaixBertrand Jean-ClaudeBen Allal
• Organismes : Research Institute of the McGill University Health Centre Centre de Recherches en Cancérologie de Toulouse Oncopole Claudius Regaud Oncopole Claudius Regaud Simulation & Modelling : Adaptive Response for Therapeutics in Cancer Oncopole Claudius Regaud Université de Provence - Aix-Marseille 1 Centre de Recherches en Cancérologie de Toulouse
• Publié dans Pharmaceuticals le 26/10/2020

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Résumé : The clinical use of cytotoxic agents is plagued by systemic toxicity. We report a novel approach that seeks to design a “combi-molecule” to behave as an alkylating agent on its own and to undergo acid-catalyzed conversion to two bioactive species at a pH range akin to that of a tumor microenvironment: an AL530 prototype was synthesized and we studied its ability to release a chlorambucil analogue (CBL-A) plus a potent mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitor (PD98059) at different pHs in buffered solutions, plasma and tumors. Its potency was compared in vitro with CBL+PD98059 (SRB assay) and in vivo in a xenograft model. Its target modulation was studied by western blotting and immunohistochemistry. AL530 released PD98059+CBL-A at mild acidic pH and in vitro was fivefold more potent than CBL and three-to-fivefold more potent than CBL+PD98059. In vivo it released high levels of PD98059 in tumors with a tumor/plasma ratio of five. It induced γ-H2AX phosphorylation and blocked pErk1,2, indirectly indicating its ability to damage DNA and modulate MEK. It induced significant tumor delay and less toxicity at unachievable doses for CBL and CBL+PD98059. We demonstrated the feasibility of a pH-labile combi-molecule capable of delivering high MEK inhibitor concentration in tumors, damaging DNA therein, and inducing tumor growth delay.

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• Type de publi. : Article dans une revue
• Date de publi. : 16/02/2021
• Auteurs : Philippe Van De PerreJean-Pierre MolesNicolas NagotEdouard TuaillonPierre‐emmanuel CeccaldiAmeena GogaAndrew J PrendergastNigel Rollins
• Organismes : Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Pathogenesis and Control of Chronic and Emerging Infections Epidémiologie et Physiopathologie des Virus Oncogènes / Oncogenic Virus Epidemiology and Pathophysiology University of Pretoria [South Africa] Queen Mary University of London Organisation Mondiale de la Santé / World Health Organization Office [Genève, Suisse]
• Publié dans Pediatric Allergy and Immunology le 02/11/2020

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Résumé : As breastfeeding is of utmost importance for child development and survival, identifying whether breast milk is a route of transmission for human viruses is critical. Based on the principle of Koch’s postulate, we propose an analytical framework to determine the plausibility of viral transmission by breast milk. This framework is based on five criteria: viral infection in children receiving breastmilk from infected mothers; the presence of virus, viral antigen or viral genome in the breast milk of infected mothers; the evidence for the virus in breast milk being infectious; the attempts to rule out other transmission modalities; and the reproduction of viral transmission by oral inoculation in an animal model. We searched for evidence in published reports to determine whether the 5 criteria are fulfilled for 16 human viruses that are suspected to be transmissible by breast milk. We considered breast milk transmission is proven if all 5 criteria are fulfilled, as probable if 4 of the 5 criteria are met, as possible if 3 of the 5 criteria are fulfilled and as unlikely if less than 3 criteria are met. Only five viruses have proven transmission through breast milk: human T‐cell lymphotropic virus 1, human immunodeficiency virus, human cytomegalovirus, dengue virus and Zika virus. The other 11 viruses fulfilled some but not all criteria and were categorized accordingly. Our framework analysis is useful for guiding public health recommendations and for identifying knowledge gaps amenable to original experiments

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Fichiers liés : Revisiting koch's postulate to determine the plausibility of viral transmission.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 15/02/2021
• Auteurs : Giske OpheimAnja van Der KolkKarin Markenroth BlochAlbert ColonKathryn DavisThomas HenryJacobus F.A. JansenStephen JonesJullie PanKarl RösslerJoel SteinMaria StrandbergSiegfried TrattnigPierre-Francois van de MoorteleMaria Isabel VargasIrène WangFabrice BartolomeiNeda BernasconiAndrea BernasconiBoris C BernhardtIsabella Björkman-BurtscherMirco CosottiniSandhitsu DasLucie Hertz-PannierSara InatiMichael JurkiewiczAli KhanShuli LiangRuoyun Emily MaSrinivasan MukundanHeath PardoeLars PinborgJonathan PolimeniJean‐philippe RanjevaEsther SteijversSteven StufflebeamTim VeersemaAlexandre VignaudNatalie VoetsSerge VulliemozChristopher WigginsRong XueRenzo GuerriniMaxime Guye
• Organismes : Neurobiology Research Unit, Department of Neurology Rigshospitalet Copenhagen University Hospital, UCPH Faculty of Health and Medical Sciences, UCPH Utrecht Brain Center [UMC] Department of Radiology University Medical Center Utrecht Skane University Hospital [Lund] Department of Neurology Neurophysiology and Neurosurgery, ACE Kempenhaeghe/MUMC, Heeze/Maastricht PENN Epilepsy Center Department of Neurology University of Minnesota, Minneapolis Department of Radiology and Nuclear Medicine Maastricht University Medical Center School for Mental Health and Neuroscience [Maastricht] Imaging Institute [Cleveland] University of Pittsburgh Medical University of Vienna = Medizinische Universität Wien Department of Radiology Hospital of the University of Pennsylvania, Philadelphia Skane University Hospital [Lund] Medical University of Vienna = Medizinische Universität Wien Medical University of Vienna = Medizinische Universität Wien Center for Magnetic Resonance Research [Minneapolis] Neuroradiology Division, Diagnostic Unit University Hospitals and Faculty of Medicine of Geneva Epilepsy Center Cleveland Clinic Institut de Neurosciences des Systèmes Service de neurophysiologie clinique [Hôpital de la Timone - APHM] McConnell Brain Imaging Centre McConnell Brain Imaging Centre McConnell Brain Imaging Centre Göteborgs Universitet = University of Gothenburg Department of Translational Research on New Technologies in Medicine and Surgery Department of Neurology University of Pennsylvania, Philadelphia Building large instruments for neuroimaging: from population imaging to ultra-high magnetic fields EEG Section, NINDS, NIH, Bethesda University of Western Ontario Imaging Research Laboratories, Robarts Research Institute, London Functional Neurosurgery Department Beijing Children's Hospital of Capital Medical University, Beijing Center for Magnetic Resonance Research [Minneapolis] Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston Epilepsy Clinic, Department of Neurology, Rigshospitalet Copenhagen University Hospital Neurobiology Research Unit, Department of Neurology Rigshospitalet Copenhagen University Hospital, UCPH Harvard-MIT Division of Health Sciences and Technology [Cambridge] Athinoula A. Martinos Center for Biomedical Imaging Centre de résonance magnétique biologique et médicale Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - APHM] Scannexus Ultrahigh Field MRI Research Center, Maastricht Harvard-MIT Division of Health Sciences and Technology [Cambridge] Athinoula A. Martinos Center for Biomedical Imaging Department of Radiology and Nuclear Medicine Meander Medical Center, Amersfoort Laboratoire d'Imagerie et de Spectroscopie Wellcome Trust Centre for Integrative Neuroimaging Université de Genève = University of Geneva Scannexus Ultrahigh Field MRI Research Center, Maastricht Beijing Normal University Università degli Studi di Firenze = University of Florence = Université de Florence IMAGO 7 Foundation, Florence Centre de résonance magnétique biologique et médicale Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - APHM]
• Publié dans Neurology le 01/11/2020

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Résumé : Identifying a structural brain lesion on MRI has important implications in epilepsy and is the most important factor that correlates with seizure freedom after surgery in patients with drug-resistant focal onset epilepsy. However, at conventional magnetic field strengths (1.5 and 3T), only approximately 60%–85% of MRI examinations reveal such lesions. Over the last decade, studies have demonstrated the added value of 7T MRI in patients with and without known epileptogenic lesions from 1.5 and/or 3T. However, translation of 7T MRI to clinical practice is still challenging, particularly in centers new to 7T, and there is a need for practical recommendations on targeted use of 7T MRI in the clinical management of patients with epilepsy. The 7T Epilepsy Task Force—an international group representing 21 7T MRI centers with experience from scanning over 2,000 patients with epilepsy—would hereby like to share its experience with the neurology community regarding the appropriate clinical indications, patient selection and preparation, acquisition protocols and setup, technical challenges, and radiologic guidelines for 7T MRI in patients with epilepsy. This article mainly addresses structural imaging; in addition, it presents multiple nonstructural MRI techniques that benefit from 7T and hold promise as future directions in epilepsy. Answering to the increased availability of 7T MRI as an approved tool for diagnostic purposes, this article aims to provide guidance on clinical 7T MRI epilepsy management by giving recommendations on referral, suitable 7T MRI protocols, and image interpretation.

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• Type de publi. : Article dans une revue
• Date de publi. : 12/02/2021
• Auteurs : Tom Le VoyerCyril GitiauxFrançois Jérôme AuthierChristine BodemerIsabelle MelkiPierre QuartierFlorence AeschlimannArnaud IsapofJean Philippe HerbeuvalVincent BondetJean-Luc CharuelMarie-Louise FrémondDarragh DuffyMathieu P RoderoBrigitte Bader-Meunier
• Organismes : Service d'immuno-hématologie pédiatrique [CHU Necker] Human genetics of infectious diseases : Mendelian predisposition Hôpital Necker - Enfants Malades [AP-HP] Université Paris Cité Institut Mondor de Recherche Biomédicale Département de pathologie [Mondor] Service de dermatologie [CHU Necker] Service d'immuno-hématologie pédiatrique [CHU Necker] Laboratory of neurogenetics and neuroinflammation AP-HP Hôpital universitaire Robert-Debré [Paris] Service d'immuno-hématologie pédiatrique [CHU Necker] Imagine - Institut des maladies génétiques (IHU) Service d'immuno-hématologie pédiatrique [CHU Necker] Imagine - Institut des maladies génétiques (IHU) CHU Trousseau [APHP] Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques Immunologie Translationnelle - Translational Immunology lab CHU Pitié-Salpêtrière [AP-HP] Laboratory of neurogenetics and neuroinflammation Immunologie Translationnelle - Translational Immunology lab Laboratoire de Chimie et de Biochimie Pharmacologiques et Toxicologiques Service d'immuno-hématologie pédiatrique [CHU Necker] Imagine - Institut des maladies génétiques (IHU)
• Publié dans Rheumatology le 29/10/2020

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Résumé : Objective To evaluate the efficacy and safety of Janus kinase inhibitors (JAKis) in JDM. Methods We conducted a single-centre retrospective study of patients with JDM treated by JAKi with a follow-up of at least 6 months. Proportion of clinically inactive disease (CID) within 6 months of JAKi initiation was evaluated using PRINTO criteria and skin Disease Activity Score. Serum IFN-α concentration was measured by Simoa assay. Results Nine refractory and one new-onset patients with JDM treated with ruxolitinib (n = 7) or baricitinib (n = 3) were included. The main indications for treatment were refractory muscle involvement (n = 8) and ulcerative skin disease (n = 2). CID was achieved in 5/10 patients (two/two anti-MDA5, three/four anti-NXP2, zero/three anti-TIF1γ-positive patients) within 6 months of JAKi introduction. All responders could withdraw plasmatic exchange, immunoadsorption and other immunosuppressive drugs. The mean daily steroid dose decreased from 1.1 mg/kg (range 0.35–2 mg/kg/d) to 0.1 (range, 0–0.3, P = 0.008) in patients achieving CID, and was stopped in two. Serum IFN-α concentrations were elevated in all patients at the time of treatment initiation and normalized in both responder and non-responder. A muscle biopsy repeated in one patient 26 months after the initiation of JAKi, showed a complete restoration of muscle endomysial microvascular bed. Herpes zoster and skin abscesses developed in three and two patients, respectively. Conclusion JAKis resulted in a CID in a subset of new-onset or refractory patients with JDM and may dramatically reverse severe muscle vasculopathy. Overall tolerance was good except for a high rate of herpes zoster infection.

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Fichiers liés : JAKiDMRheumatologyREVISEDFINAL.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 11/02/2021
• Auteurs : P. RichetteAugustin LatourteJérémie SellamDaniel WendlingMuriel PipernoPhilippe GoupilleYves-Marie PersFlorent EymardSebastien OttavianiPaul OrnettiRené-Marc FlipoBruno FautrelOlivier PeyrJean Pierre BertolaÉric VicautXavier Chevalier
• Organismes : Service de Rhumatologie [CHU Lariboisière] Service de Rhumatologie [CHU Lariboisière] Pathologies biliaires, fibrose et cancer du foie [CRSA] Service de Rhumatologie Université Claude Bernard Lyon 1 CHU Trousseau [Tours] Centre Hospitalier Régional Universitaire [Montpellier] Cellules Souches, Plasticité Cellulaire, Médecine Régénératrice et Immunothérapies (IRMB) Service de rhumatologie [CHU Henri Mondor] Université Paris-Est Créteil Val-de-Marne - Paris 12 AP-HP - Hôpital Bichat - Claude Bernard [Paris] Service de Rhumatologie (CHU de Dijon) Service de rhumatologie[Lille] Institut Pierre Louis d'Epidémiologie et de Santé Publique Service de Rhumatologie [CHU Lariboisière] Chugai Pharma France, Paris La Défense Hôpital Lariboisière-Fernand-Widal [APHP] Service de rhumatologie [CHU Henri Mondor] Université Paris-Est Créteil Val-de-Marne - Paris 12
• Publié dans Annals of the Rheumatic Diseases le 26/10/2020

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Résumé : Objective: To evaluate the efficacy of tocilizumab, an antibody against IL-6 receptor, in patients with hand osteoarthritis. Methods: This was a multicentre, 12-week, randomised, double-blind, placebo-controlled study from November 2015 to October 2018. Patients with symptomatic hand osteoarthritis (pain ≥40 on a 0–100 mm visual analogue scale (VAS) despite analgesics and non-steroidal anti-inflammatory drugs; at least three painful joints, Kellgren-Lawrence grade ≥2) were randomised to receive two infusions 4 weeks apart (weeks 0 and 4) of tocilizumab (8 mg/kg intravenous) or placebo. The primary endpoint was changed in VAS pain at week 6. Secondary outcomes included the number of painful and swollen joints, duration of morning stiffness, patients’ and physicians’ global assessment and function scores. Results: Of 104 patients screened, 91 (45 to tocilizumab and 46 to placebo; 82% women; mean age 64.4 (SD 8.7) years) were randomly assigned and 79 completed the 12-week study visit. The mean change between baseline and week 6 on the VAS for pain (primary outcome) was −7.9 (SD 19.4) and −9.9 (SD 20.1) in the tocilizumab and placebo groups (p=0.7). The groups did not differ for any secondary outcomes at weeks 4, 6, 8 or 12. Overall, adverse events were slightly more frequent in the tocilizumab than placebo group. Conclusion: Tocilizumab was no more effective than placebo for pain relief in patients with hand osteoarthritis.

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• Type de publi. : Article dans une revue
• Date de publi. : 11/02/2021
• Auteurs : Anne-Sophie GilleCatherine PatratJean-Hugues DalleFrançoise BernaudinCéline ChalasMony FahdCamille JeanHarry LezeauLydia RiouVéronique DrouineaudAnnabel Paye-JaouenAnnie KamdemBénédicte NevenCécile ArnaudSaba AzarnoushKarima YakoubenSabine SarnackiMariane de MontalembertEva Maria ComperatGilles LenaourMathilde SibonyNathalie DhédinDaniel VaimanJean-Philippe WolfCatherine PatratPierre FouchetCatherine PoirotVirginie Barraud-Lange
• Organismes : Université Paris Cité Université Paris Cité
• Publié dans Blood le 28/10/2020

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Résumé : In these two short reports, the authors approach the issue of whether hydroxyurea (HU) use in young males has major irreversible effects on sperm production. Joseph et al analyzed and compared sperm parameters in male patients with sickle cell disease (SCD) who were exposed or not exposed to HU before puberty. They report semen abnormalities in all patients but no differences between groups. Independently, Gille et al provide evidence for the lack of in vivo HU-related decreases in the spermatogonial pool in biopsy specimens from young males with SCD but evidence for a negative effect of SCD itself. Together, these reports suggest that the use of HU in young males does not adversely affect fertility.

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Fichiers liés : 1-s2.0-S0006497121002834-main.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 11/02/2021
• Auteurs : Renaud FeltenValérie Devauchelle-PensecRaphaèle SerorPierre DuffauDavid SaadounÉric HachullaPierre-Yves HatronCarine SalliotAleth PerdrigerJacques MorelArsène MékinianOlivier VittecoqJean-Marie BerthelotEmanuelle DernisVeronique Le GuernPhilippe DieudéClaire LarrocheChristophe RichezThierry MartinCharles ZarnitskyGilles BlaisonPierre KiefferFrançois MaurierAzeddine DellalStephanie RistEmmanuel AndrèsAnne ContisEmmanuel ChatelusChristelle SordetJean SibiliaCécile ArnoldMira TawkOuafaa AberkaneLise HolterbachPatrice CacoubAlain SarauxXavier MarietteNicolas MeyerJacques-Eric Gottenberg
• Organismes : Service de rhumatologie [Strasbourg] CHRU Brest - Service de Rhumatologie Service de Rhumatologie [CHU Bicêtre] Service de médecine interne et maladies infectieuses [Bordeaux] CHU Pitié-Salpêtrière [AP-HP] Service de médecine interne [Lille] Service de médecine interne [Lille] Centre Hospitalier Regional d'Orléans Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Centre Hospitalier Régional Universitaire [Montpellier] Institut de Génétique Moléculaire de Montpellier CHU Saint-Antoine [AP-HP] Service de Rhumatologie [CHU Rouen] Service de rhumatologie [Nantes] Service de Rhumatologie [CH Le Mans] Service de médecine interne et centre de référence des maladies rares [CHU Cochin] AP-HP - Hôpital Bichat - Claude Bernard [Paris] Service de médecine interne [Avicenne] Hôpital Pellegrin Centre Hospitalier Universitaire [Strasbourg] Groupe Hospitalier du Havre Hôpital Jacques Monod (MONTIVILLIERS) CH Colmar Centre Hospitalier Emile Muller [Mulhouse] Hôpital Sainte Blandine Groupe Hospitalier Intercommunal Le Raincy-Montfermeil Centre Hospitalier Regional d'Orléans Centre Hospitalier Universitaire [Strasbourg] Service de médecine interne et maladies infectieuses [Bordeaux] Service de rhumatologie [Strasbourg] Service de rhumatologie [Strasbourg] Service de rhumatologie [Strasbourg] Centre Hospitalier Universitaire [Strasbourg] Centre Hospitalier Universitaire [Strasbourg] Centre Hospitalier Universitaire [Strasbourg] Centre Hospitalier Universitaire [Strasbourg] CHU Pitié-Salpêtrière [AP-HP] CHRU Brest - Service de Rhumatologie Service de Rhumatologie [CHU Bicêtre] Centre Hospitalier Universitaire [Strasbourg] Service de rhumatologie [Strasbourg]
• Publié dans Annals of the Rheumatic Diseases le 26/10/2020

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Résumé : Objectives No immunomodulatory drug has been approved for primary Sjögren’s syndrome, a systemic autoimmune disease affecting 0.1% of the population. To demonstrate the efficacy of targeting interleukin 6 receptor in patients with Sjögren’s syndrome-related systemic complications. Methods Multicentre double-blind randomised placebo-controlled trial between 24 July 2013 and 16 July 2018, with a follow-up of 44 weeks, involving 17 referral centres. Inclusion criteria were primary Sjögren’s syndrome according to American European Consensus Group criteria and score ≥5 for the EULAR Sjögren’s Syndrome Disease activity Index (ESSDAI, score of systemic complications). Patients were randomised to receive either 6 monthly infusions of tocilizumab or placebo. The primary endpoint was response to treatment at week 24. Response to treatment was defined by the combination of (1) a decrease of at least 3 points in the ESSDAI, (2) no occurrence of moderate or severe activity in any new domain of the ESSDAI and (3) lack of worsening in physician’s global assessment on a Visual Numeric Scale ≥1/10, all as compared with enrolment. Results 110 patients were randomised, 55 patients to tocilizumab (mean (SD) age: 50.9 (12.4) years; women: 98.2%) and 55 patients to placebo (54.8 (10.7) years; 90.9%). At 24 weeks, the proportion of patients meeting the primary endpoint was 52.7% (29/55) in the tocilizumab group and 63.6% (35/55) in the placebo group, for a difference of −11.4% (95% credible interval −30.6 to 9.0) (Pr[Toc >Pla]=0.14). Conclusion Among patients with primary Sjögren’s syndrome, the use of tocilizumab did not improve systemic involvement and symptoms over 24 weeks of treatment compared with placebo. Trial registration number NCT01782235 .

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• Type de publi. : Article dans une revue
• Date de publi. : 10/02/2021
• Auteurs : Carole FritzGilles ToselloGuillaume FleuryEmmanuel KasarherouPhilippe WalterFrancis DuranthonPascal GaillardJulien Tardieu
• Organismes : Maison des Sciences de l'Homme et de la Société de Toulouse Travaux et recherches archéologiques sur les cultures, les espaces et les sociétés Maison des Sciences de l'Homme et de la Société de Toulouse Muséum de Toulouse Musée du quai Branly – Jacques Chirac Laboratoire d'Archéologie Moléculaire et Structurale Muséum de Toulouse Cognition, langues, langage, ergonomie Maison des Sciences de l'Homme et de la Société de Toulouse Maison des Sciences de l'Homme et de la Société de Toulouse
• Publié dans Science Advances le 21/10/2020

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Résumé : Anthropologists and ethnomusicologists assert that there is no society without song, and more specifically, there is no ritual or celebration without accompanying sound. The production of sounds in social contexts is very ancient. Here, we report on the study of a seashell from the decorated cave of Marsoulas and demonstrate that the Magdalenian occupants of this site transformed this shell into a wind instrument. It is one of the very rare examples, if not the only one for the Paleolithic period, of a musical instrument fashioned from a large shell, and the first conch shell of this use thus far discovered. We already know that prehistoric people transformed many shells into portable ornaments and that they thus attributed substantial corporal symbolism to them. This seashell horn, with its unique sonority, both deep and strong with an enduring reverberation, sheds light on a musical dimension until now unknown in the context of Upper Paleolithic societies.

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Fichiers liés : eabe9510.full.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 08/02/2021
• Auteurs : Nguyen Bich NgocP. DiepHarriet ParsonsKate PattleThiem HoangDaniel R. van RossumLe Ngoc TramCharles L H HullMehrnoosh TahaniRay FuruyaPierre BastienKeping QiuTetsuo HasegawaWoojin KwonYasuo DoiShih-Ping LaiSimon CoudéDavid BerryTao-Chung ChingJihye HwangArchana SoamJia-Wei WangDoris ArzoumanianTyler BourkeDo-Young ByunHuei-Ru Vivien ChenZhiwei ChenWen Ping ChenMike ChenJungyeon ChoYunhee ChoiMinho ChoiA. ChrysostomouEun Jung ChungSophia DaiJames Di FrancescoYan DuanHao-Yuan DuanD. EdenChakali EswaraiahLapo FanciulloJason FiegeLaura FisselErica FranzmannPer FribergRachel FriesenGary FullerTim GledhillSarah GravesJane GreavesMatt GriffinQi-Lao 琦烙 Gu 顾Ilseung HanJennifer HatchellSaeko HayashiMartin HoudeTsuyoshi InoueShu-Ichiro InutsukaKazunari IwasakiIl-Gyo JeongDoug JohnstoneJi-Hyun KangSung-Ju KangMiju KangAkimasa KataokaKoji S KawabataFrancisca KemperKee-Tae KimJongsoo KimTae-Soo PyoLei QianRamprasad RaoMark RawlingsJonathan RawlingsBrendan RetterJohn RicherAndrew RigbySarah SadavoyHiro SaitoGiorgio SaviniAnna ScaifeMasumichi SetaGwanjeong KimShinyoung KimKyoung Hee KimMi-Ryang KimFlorian KirchschlagerJason KirkMasato KobayashiPatrick M KochVera KönyvesTakayoshi KusuneJungmi KwonKevin LacailleChi-Yan LawSang-Sung LeeYong-Hee LeeChin-Fei LeeJeong-Eun LeeHyeseung LeeC.-W. LeeDi LiHua-Bai LiDalei LiHong-Li LiuJunhao LiuTie 铁 Liu 刘Sheng-Yuan LiuXing LuA.-Ran LyoSteve MairsMasafumi 雅文 Matsumura 松村Brenda MatthewsGerald Moriarty-SchievenTetsuya NagataSandhyarani PanigrahyHiroyuki NakanishiNagayoshi OhashiTakashi OnakaGeumsook ParkNicolas PerettoYoshito ShimajiriHiroko ShinnagaMotohide TamuraYa-Wen TangXindi TangKohji TomisakaYusuke TsukamotoSerena VitiHongchi WangAnthony WhitworthJinjin XieHsi-Wei YenHyunju YooJinghua YuanHyeong-Sik YunTetsuya ZenkoYapeng ZhangChuan-Peng ZhangGuoyin ZhangJianjun ZhouLei ZhuIlse De LoozePh. AndréC. Darren DowellStewart EyresSam FalleJean-François RobitailleSven van Loo
• Organismes : Vietnam Academy of Science and Technology [Hanoi] Vietnam Academy of Science and Technology [Hanoi] Korea Astronomy and Space Science Institute Stratospheric Observatory for Infrared Astronomy
• Publié dans The Astrophysical Journal le 22/10/2020

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Résumé : Abstract We report the first high spatial resolution measurement of magnetic fields surrounding LkHα 101, part of the Auriga–California molecular cloud. The observations were taken with the POL-2 polarimeter on the James Clerk Maxwell Telescope within the framework of the B-fields In Star-forming Region Observations (BISTRO) survey. Observed polarization of thermal dust emission at 850 μm is found to be mostly associated with the redshifted gas component of the cloud. The magnetic field displays a relatively complex morphology. Two variants of the Davis–Chandrasekhar–Fermi method, unsharp masking and structure function, are used to calculate the strength of magnetic fields in the plane of the sky, yielding a similar result of BPOS ∼ 115 μG. The mass-to-magnetic-flux ratio in critical value units, λ ∼ 0.3, is the smallest among the values obtained for other regions surveyed by POL-2. This implies that the LkHα 101 region is subcritical, and the magnetic field is strong enough to prevent gravitational collapse. The inferred δB/B 0 ∼ 0.3 implies that the large-scale component of the magnetic field dominates the turbulent one. The variation of the polarization fraction with total emission intensity can be fitted by a power law with an index of α = 0.82 ± 0.03, which lies in the range previously reported for molecular clouds. We find that the polarization fraction decreases rapidly with proximity to the only early B star (LkHα 101) in the region. Magnetic field tangling and the joint effect of grain alignment and rotational disruption by radiative torques can potentially explain such a decreasing trend.

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• Type de publi. : Article dans une revue
• Date de publi. : 08/02/2021
• Auteurs : Daniel J. KlionskyAmal Kamal Abdel-AzizSara AbdelfatahMahmoud AbdellatifAsghar AbdoliSteffen AbelHagai AbeliovichMarie AbildgaardYakubu Princely AbuduAbraham Acevedo-ArozenaIannis AdamopoulosKhosrow AdeliTimon AdolphAnnagrazia AdornettoElma AflakiGalila AgamAnupam AgarwalBharat AggarwalMaria AgnelloPatrizia AgostinisJaved AgrewalaAlexander AgrotisPatricia AguilarS. Tariq AhmadZubair AhmedUlises Ahumada-CastroSonja AitsShu AizawaYunus AkkocTonia AkoumianakiHafize Aysin AkpinarAhmed Al-AbdLina Al-AkraAbeer Al-GharaibehMoulay Alaoui-JamaliSimon AlbertiElísabet Alcocer-GómezCristiano AlessandriMuhammad AliM. Abdul Alim Al-BariSaeb AliwainiJavad AlizadehEugènia AlmacellasAlexandru AlmasanAlicia AlonsoGuillermo AlonsoNihal Altan-BonnetDario AltieriÉlida ÁlvarezSara AlvesCristine Alves da CostaMazen AlzaharnaMarialaura AmadioConsuelo AmantiniCristina AmaralSusanna AmbrosioAmal AmerVeena AmmanathanZhenyi AnStig AndersenShaida AndrabiMagaiver Andrade-SilvaAllen AndresSabrina AngeliniDavid AnnUche AnozieMohammad AnsariPedro AntasAdam AntebiZuriñe AntónTahira AnwarLionel ApetohNadezda ApostolovaToshiyuki ArakiYasuhiro ArakiKohei ArasakiWagner AraújoJun ArayaCatherine ArdenMaria-Angeles ArévaloSandro ArguellesEsperanza AriasJyothi ArikkathHirokazu ArimotoAileen AriosaDarius Armstrong-JamesLaetitia Arnauné-PelloquinAngeles ArocaDaniela ArroyoIvica ArsovRubén ArteroDalia Maria Lucia AsaroMichael AschnerMilad AshrafizadehOsnat Ashur-FabianAtanas AtanasovAlicia AuPatrick AubergerHolger AunerLaure AurelianRiccardo AutelliLaura AvaglianoYenniffer ÁvalosSanja AveicCélia Alexandra AveleiraTamar Avin-WittenbergYucel AydinScott AytonSrinivas AyyadevaraMaria AzzopardiMisuzu BabaJonathan BackerSteven BackuesDong-Hun BaeOk-Nam BaeSoo Han BaeEric BaehreckeAhruem BaekSeung-Hoon BaekSung Hee BaekGiacinto BagettaAgnieszka Bagniewska-ZadwornaHua BaiJie BaiXiyuan BaiYidong BaiNandadulal BairagiShounak BaksiTeresa BalbiCosima BaldariWalter BalduiniAndrea BallabioMaria BallesterSalma BalazadehRena BalzanRina BandopadhyaySreeparna BanerjeeSulagna BanerjeeÁgnes BánrétiYan BaoMauricio BaptistaAlessandra BaraccaCristiana BarbatiAriadna BargielaDaniela BarilàPeter BarlowSami BarmadaEsther BarreiroGeorge BarretoJiri BartekBonnie BartelAlberto BartolomeGaurav BarveSuresh BasagoudanavarDiane BasshamRobert BastAlakananda BasuHenri BatokoIsabella BattenEtienne BaulieuBradley BaumgarnerJagadeesh BayryRupert BealeIsabelle BeauFlorian BeaumatinLuiz R.G. BecharaGeorge BeckMichael BeersJakob BegunChristian BehrendsGeorg M.N. BehrensRoberto BeiEloy BejaranoShai BelChristian BehlAmine BelaidNaïma Belgareh-TouzéCristina BellarosaFrancesca BelleudiMelissa Belló PérezRaquel Bello-MoralesJackeline Soares de Oliveira BeltranSebastián BeltranDoris Mangiaracina BenbrookMykolas BendoriusBruno BenitezIrene Benito-CuestaJulien BensalemMartin BerchtoldSabina BerezowskaDaniele BergamaschiMatteo BergamiAndreas BergmannLaura BerliocchiClarisse Berlioz-TorrentAmélie BernardLionel BerthouxCagri BesirliSébastien BesteiroVirginie BetinRudi BeyaertJelena BezbradicaKiran BhaskarIngrid Bhatia-KissovaResham BhattacharyaSujoy BhattacharyaShalmoli BhattacharyyaMd. Shenuarin BhuiyanSujit Kumar BhutiaLanrong BiXiaolin BiTrevor BidenKrikor BijianViktor BillesNadine BinartClaudia BincolettoAsa BirgisdottirGeir BjorkoyGonzalo BlancoAna Blas-GarciaJanusz BlasiakRobert BlomgranKlas BlomgrenJanice BlumEmilio Boada-RomeroMirta BobanKathleen Boesze-BattagliaPhilippe BoeufBarry BolandPascale BomontPaolo BonaldoSrinivasa Reddy BonamLaura BonfiliJuan BonifacinoBrian BooneMartin BootmanMatteo BordiChristoph BornerBeat BornhauserGautam BorthakurJürgen BoschSantanu BoseLuis BotanaJuan BotasChantal BoulangerMichael BoultonMathieu BourdenxBenjamin BourgeoisNollaig BourkeGuilhem BousquetPatricia BoyaPeter BozhkovLuiz BoziTolga BozkurtDoug BrackneyChristian BrandtsRalf BraunGerhard BrausRoberto Bravo-SaguaJosé M. Bravo-San PedroPatrick BrestMarie-Agnès BringerAlfredo Briones-HerreraV. Courtney BroaddusPeter BrodersenJeffrey BrodskySteven BrodyPaola BronsonJeff BronsteinCarolyn BrownRhoderick BrownPatricia BrumJohn BrumellNicola Brunetti-PierriDaniele BrunoRobert Bryson-RichardsonCecilia BucciCarmen BuchrieserMarta BuenoLaura Elisa Buitrago-MolinaSimone BuraschiShilpa BuchJ. Ross BuchanErin BuckinghamHikmet BudakMauricio BudiniGeert BultynckFlorin BuradaJoseph BurgoyneM. Isabel BurónVictor BustosSabrina BüttnerElena ButturiniAaron ByrdIsabel CabasSandra Cabrera-BenitezKen CadwellJingjing CaiLu CaiQian CaiMontserrat CairóJose CalbetGuy CaldwellKim CaldwellJarrod CallRiccardo CalvaniAna CalvoMiguel Calvo-Rubio BarreraNiels Os CamaraJacques H. CamonisNadine CamougrandMichelangelo CampanellaEdward CampbellFrançois-Xavier Campbell-ValoisSilvia CampelloIlaria CampesiJuliane CamposOlivier CamuzardJorge CancinoDanilo Candido de AlmeidaLaura CanesiIsabella CaniggiaBarbara CanonicoCarles CantíBin CaoMichele CaragliaBeatriz CaramésEvie CarchmanElena Cardenal-MuñozCésar CárdenasLuis CardenasSandra CardosoJennifer CarewGeorges F CarleGillian CarletonSilvia CarloniDidac Carmona-GutierrezLeticia CarneiroOliana CarnevaliJulian CarosiSerena CarraAlice CarrierLucie CarrierBernadette CarrollA. Brent CarterAndreia Neves CarvalhoMagali CasanovaCaty CasasJosefina CasasChiara CassioliEliseo CastilloKaren CastilloSonia Castillo-LluvaFrancesca CastoldiMarco CastoriAriel CastroMargarida Castro-CaldasJavier Castro-HernandezSusana Castro-ObregonSergio CatzClaudia CavadasFederica CavaliereGabriella CavalliniMaria CavinatoMaría L CayuelaPaula Cebollada RicaValentina CecariniFrancesco CecconiMarzanna Cechowska-PaskoSimone CenciVictòria Ceperuelo-MallafréJoão CerqueiraJanete CeruttiDavide CerviaVildan Bozok CetintasSilvia CetrulloHan-Jung ChaeAndrei ChaginChee-Yin ChaiGopal ChakrabartiOishee ChakrabartiTapas ChakrabortyTrinad ChakrabortyMounia ChamiGeorgios ChamilosDavid ChanEdmond ChanEdward ChanH.Y. Edwin ChanHelen ChanHung ChanMatthew T.V. ChanYau Sang ChanPartha ChandraChih-Peng ChangChunmei ChangHao-Chun ChangKai ChangJie ChaoTracey ChapmanNicolas Charlet-BerguerandSamrat ChatterjeeShail ChaubeAnu ChaudharySantosh ChauhanEdward ChaumFrédéric CheclerMichael CheethamChang-Shi ChenGuang-Chao ChenJian-Fu ChenLiam ChenLeilei ChenLin ChenMingliang ChenMu-Kuan ChenNing ChenQuan ChenRuey-Hwa ChenShi ChenShanhong ChenWeiqiang ChenXin-Ming ChenXiong-Wen ChenXu ChenYan ChenYe-Guang ChenYingyu ChenYongqiang ChenYu-Jen ChenYue-Qin ChenZhefan Stephen ChenZhi ChenZhi-Hua ChenZhijian ChenZhixiang ChenHanhua ChengJun ChengShi-Yuan ChengWei ChengXiaodong ChengXiu-Tang ChengYiyun ChengZhiyong ChengZhong ChenHeesun CheongJit Kong CheongBoris ChernyakSara CherryChi Fai Randy CheungChun Hei Antonio CheungKing-Ho CheungEric ChevetRichard ChiAlan Kwok Shing ChiangFerdinando ChiaradonnaRoberto ChiarelliMario ChiarielloNathalia ChicaSusanna ChioccaMario ChiongShih-Hwa ChiouAbhilash ChiramelValerio ChiurchiùDong-Hyung ChoSeong-Kyu ChoeAugustine M.K. ChoiMary ChoiKamalika Roy ChoudhuryNorman ChowCharleen ChuJason ChuaJohn Jia En ChuaHyewon ChungKin Pan ChungSeockhoon ChungSo-Hyang ChungYuen-Li ChungValentina CianfanelliIwona CiechomskaMariana CifuentesLaura CinqueSebahattin CirakMara CironeMichael ClagueRobert ClarkeEmilio ClementiEliana CocciaPatrice CodognoEhud CohenMickael M. CohenTania ColasantiFiorella ColasuonnoRobert ColbertAnna ColellMiodrag ČolićNuria CollMark CollinsMaría ColomboDaniel Colón-RamosLydie CombaretSergio CominciniMárcia CominettiAntonella ConsiglioAndrea ConteFabrizio ContiViorica Raluca ContuMark CooksonKevin CoombsIsabelle CoppensMaria Tiziana CorasanitiDale CorkeryNils CordesKatia CorteseMaria Do Carmo CostaSarah CostantinoPaola CostelliAna Coto-MontesPeter CrackJose CrespoAlfredo CriolloValeria CrippaRiccardo CristofaniTamas CsizmadiaAntonio CuadradoBing CuiJun CuiYixian CuiYong CuiEmmanuel CulettoAndrea CuminoAndrey CybulskyMark CzajaStanislaw CzuczwarStefania D’adamoMarcello D’amelioDaniela D’arcangeloAndrew D’lugosGabriella D’oraziJames da SilvaHormos Salimi DafsariRuben DagdaYasin DagdasMaria DagliaXiaoxia DaiYun DaiYuyuan DaiJessica Dal ColPaul DalhaimerLuisa Dalla ValleTobias DallengaGuillaume DalmassoMarkus DammeIlaria DandoNico DantumaApril DarlingHiranmoy DasSrinivasan DasarathySantosh DasariSrikanta DashOliver DaumkeAdrian DauphineeJeffrey DaviesValeria DávilaRoger DavisTanja DavisSharadha Dayalan NaiduFrancesca de AmicisKarolien de BosscherFrancesca de FeliceLucia de FranceschiChiara de LeonibusMayara de Mattos BarbosaGuido R.Y. de MeyerAngelo de MilitoCosimo de NunzioClara de PalmaMauro de SantiClaudio de VirgilioDaniela de ZioJayanta DebnathBrian DeboschJean-Paul DecuypereMark DeehanGianluca DeflorianJames DegregoriBenjamin DehayGabriel del RioJoe DelaneyLea DelbridgeElizabeth Delorme-AxfordM. Victoria DelpinoFrancesca DemarchiVilma DembitzNicholas DemersHongbin DengZhiqiang DengJoern DengjelPaul DentDonna DentonMelvin DepamphilisChanning DerVojo DereticAlbert DescoteauxLaura DevisSushil DevkotaOlivier DevuystGrant DewsonMahendiran DharmasivamRohan DhimanDiego Di BernardoManlio Di CristinaFabio Di DomenicoPietro Di FazioAlessio Di FonzoGiovanni Di GuardoGianni Di GuglielmoLuca Di LeoChiara Di MaltaAlessia Di NardoMartina Di RienzoFederica Di SanoGeorge DiallinasJiajie DiaoGuillermo Diaz-ArayaInés Díaz-LaviadaJared DickinsonMarc DiederichMélanie DieudéIvan DikicShiping DingWen-Xing DingLuciana DiniJelena DinićMiroslav DinicAlbena Dinkova-KostovaMarc DionneJörg H.W. DistlerAbhinav DiwanIan M.C. DixonMojgan Djavaheri-MergnyIna DobrinskiOxana DobrovinskayaRadek DobrowolskiRenwick C.J. DobsonJelena ĐokićSerap Dokmeci EmreMassimo DonadelliBo DongXiaonan DongZhiwu DongGerald 2nd DornVolker DotschHuan DouJuan DouMoataz DowaidarSami DridiLiat DruckerAilian DuCaigan DuGuangwei DuHai-Ning DuLi-Lin DuAndré Du ToitShao-Bin DuanXiaoqiong DuanSónia DuarteAnna DubrovskaElaine DunlopNicolas DupontRaúl V DuránBilikere DwarakanathSergey DyshlovoyDarius Ebrahimi-FakhariLeopold EckhartCharles EdelsteinThomas EfferthEftekhar EftekharpourLudwig EichingerNabil EidTobias EisenbergN. Tony EissaSanaa EissaMiriam EjarqueAbdeljabar El AndaloussiNazira El-HageShahenda El-NaggarAnna Maria EleuteriEman El-ShafeyMohamed ElgendyAristides EliopoulosMaría ElizaldePhilip ElksHans-Peter ElsasserEslam ElsherbinyBrooke EmerlingN. EmreChristina EngNikolai EngedalAnna-Mart EngelbrechtAgnete S.T. EngelsenJorrit EnserinkRicardo EscalanteAudrey EsclatineMafalda Escobar-HenriquesEeva-Liisa EskelinenL EspertMakandjou-Ola EusebioGemma FabriasCinzia FabriziAntonio FacchianoFrancesco FacchianoBengt FadeelClaudio FaderAlex FaesenW. Douglas FairlieAlberto FalcóBjorn FalkenburgerDaping FanJie FanYanbo FanEvandro FangYanshan FangYognqi FangManolis FantoTamar Farfel-BeckerMathias FaureGholamreza FazeliAnthony FedeleArthur FeldmanDu FengJiachun FengLifeng FengYibin FengYuchen FengWei FengThais Fenz AraujoThomas FergusonÁlvaro FernándezJose Fernandez-ChecaSonia Fernández-VeledoAlisdair FernieAnthony FerranteAlessandra FerraresiMerari FerrariJulio C.B. FerreiraSusan Ferro-NovickAntonio FiguerasRiccardo FiladiNicoletta FilighedduEduardo Filippi-ChielaGiuseppe FilomeniGian Maria FimiaVittorio FineschiFrancesca FinettiSteven FinkbeinerEdward FisherPaul FisherFlavio FlamigniSteven FlieslerTrude FloIda FloranceOliver FloreyTullio FlorioErika FodorCarlo FolloEdward FonAntonella ForlinoFrancesco FornaiPaola FortiniAnna FracassiAlessandro FraldiBrunella FrancoRodrigo FrancoFlavia FranconiLisa FrankelScott FriedmanLeopold FröhlichGema FrühbeckJose FuentesYukio FujikiNaonobu FujitaYuuki FujiwaraMitsunori FukudaSimone FuldaLuc FuricNorihiko FuruyaCarmela FuscoMichaela GackLidia GaffkeSehamuddin GaladariAlessia GalassoMaria GalindoSachith Gallolu KankanamalageLorenzo GalluzziVincent GalyNoor GammohBoyi GanIan GanleyFeng GaoHui GaoMinghui GaoPing GaoShou-Jiang GaoWentao GaoXiaobo GaoAna GarceraMaria Noé GarciaVerónica GarciaFrancisco García-del PortilloVega Garcia-EscuderoAracely Garcia-GarciaMarina Garcia-MaciaDiana García-MorenoCarmen Garcia-RuizPatricia García-SanzAbhishek GargRicardo GarginiTina GarofaloRobert GarryNils GassenDamian GaticaLiang GeWanzhong GeRuth Geiss-FriedlanderCecilia GelfiPascal GenschikIan GentleValeria GerbinoChristoph GerhardtKyla GermainMarc GermainDavid GewirtzElham Ghasemipour AfsharSaeid GhavamiAlessandra GhigoManosij GhoshGeorgios GiamasClaudia GiampietriAlexandra GiatromanolakiGary GibsonSpencer GibsonVanessa GinetEdward GinigerCarlotta GiorgiHenrique GiraoStephen GirardinMridhula GiridharanSandy GiulianoCecilia GiuliviSylvie GiuriatoJulien GiustinianiAlexander GluschkoVeit GoderAlexander GoginashviliJakub GolabDavid GoldstoneAnna GolebiewskaLuciana GomesRodrigo Enrique GomezRubén Gómez-SánchezMaria Catalina Gomez-PuertoRaquel Gomez-SintesQingqiu GongFelix GoniJavier González-GallegoTomas Gonzalez-HernandezRosa Gonzalez-PoloJose Gonzalez-ReyesPatricia González-RodríguezIng Swie GopingMarina GorbatyukNikolai GorbunovKivanç GörgülüRoxana GorojodSharon GorskiSandro GoruppiCecilia GotorRoberta GottliebIllana GozesDevrim GozuacikMartin GraefMarkus GrälerVeronica GranatieroDaniel GrassoJoshua GrayDouglas GreenAlexander GreenhoughStephen GregoryEdward GriffinMark GrinstaffFrédéric GrosCharles GroseAngelina GrossFlorian GruberPaolo GrumatiTilman GruneXueyan GuJun-Lin GuanCarlos GuardiaKishore GudaFlora GuerraConsuelo GuerriPrasun GuhaCarlos GuillénShashi GujarAnna GukovskayaIlya GukovskyJan GunstAndreas GüntherAnyonya GunturChuanyong GuoChun GuoHongqing GuoLian-Wang GuoMing GuoPawan GuptaShashi Kumar GuptaSwapnil GuptaVeer Bala GuptaVivek GuptaAsa GustafssonDavid GuttermanRanjitha H.B.Annakaisa HaapasaloJames HaberAleksandra HaćShinji HadanoAnders HafrénMansour HaidarBelinda HallGunnel HalldénAnne Hamacher-BradyAndrea HamannMaho HamasakiWeidong HanMalene HansenPhyllis I.  HansonZijian HaoMasaru HaradaLjubica Harhaji-TrajkovicNirmala HariharanNigil HaroonJames HarrisTakafumi HasegawaNoor Hasima NagoorJeffrey HaspelVolker HauckeWayne HawkinsBruce HayCole HaynesSoren HayrabedyanThomas HaysCongcong HeQin HeRong-Rong HeYou-Wen HeYu-Ying HeYasser HeakalAlexander HeberleJ. Fielding HejtmancikGudmundur Vignir  HelgasonVanessa HenkelMarc HerbAlexander HergovichAnna Herman-AntosiewiczAgustín HernándezCarlos HernandezSergio Hernandez-DiazVirginia Hernandez-GeaAmaury HerpinJudit HerrerosJavier HervásDaniel HesselsonClaudio HetzVolker HeusslerYujiro HiguchiSabine HilfikerJoseph HillWilliam HlavacekEmmanuel HoIdy H.T. HoPhilip Wing-Lok HoShu-Leong HoWan Yun HoG. Aaron HobbsMark HochstrasserPeter H.M. HoetDaniel HofiusPaul HofmanAnnika HöhnCarina HolmbergJose HombrebuenoChang-Won Hong, Yi-Ren HongLora HooperThorsten HoppeRastislav HorosYujin HoshidaI-Lun HsinHsin-Yun HsuBing HuDong HuLi-Fang HuMing Chang HuRonggui HuWei HuYu-Chen HuZhuo-Wei HuFang HuaJinlian HuaYingqi HuaChongmin HuanCanhua HuangChuanshu HuangChuanxin HuangChunling HuangHaishan HuangKun HuangMichael L.H. HuangRui HuangShan HuangTianzhi HuangXing HuangYuxiang Jack HuangTobias HuberVirginie HubertChristian HubnerStephanie HughesWilliam HughesMagali HumbertGerhard HummerJames HurleySabah HussainSalik HussainPatrick HusseyMartina HutabaratHui-Yun HwangSeungmin HwangAntonio IeniFumiyo IkedaYusuke ImagawaYuzuru ImaiCarol ImbrianoMasaya ImotoDenise InmanKen InokiJuan Lucio IovannaRenato IozzoGiuseppe IppolitoJavier IrazoquiPablo IribarrenMohd IshaqMakoto IshikawaNestor IshimweCiro IsidoroNahed IsmailShohreh Issazadeh-NavikasEisuke ItakuraDaisuke ItoDavor IvankovicSaška IvanovaAnand Krishnan V. IyerJosé IzquierdoMasanori IzumiMarja JäätteläMajid Sakhi JabirWilliam JacksonNadia Jacobo-HerreraAnne-Claire JacominElise JacquinPooja JadiyaHartmut JaeschkeChinnaswamy JagannathArjen JakobiJohan JakobssonBassam JanjiPidder Jansen-DürrPatric JanssonJonathan JantschSławomir JanuszewskiAlagie JasseySteve JeanHélène JeltschPavla JendelovaAndreas JennyThomas JensenNiels JessenJenna JewellJing JiLijun JiaRui JiaLiwen JiangQing JiangRicheng JiangTeng JiangXuejun JiangYu JiangMaria Jimenez-SanchezEun-Jung JinFengyan JinHongchuan JinLi JinLuqi JinMeiyan JinSi JinEun-Kyeong JoCarine JoffreTerje JohansenGail V.W. JohnsonSimon JohnstonEija JokitaloMohit Kumar JollyLeo A.B. JoostenJoaquin JordanBertrand JosephDianwen JuJeong-Sun JuJingfang JuEsmeralda JuárezDelphine JudithGábor JuhászYoungsoo JunChang Hwa JungSung-Chul JungYong Keun JungHeinz JungbluthJohannes JungverdorbenSteffen JustKai KaarnirantaAllen KaasikTomohiro KabutaDaniel KaganovichAlon KahanaRenate KainShinjo KajimuraMaria KalamvokiManjula KaliaDanuta KalinowskiNina KaludercicIoanna KalvariJoanna KaminskaVitaliy KaminskyyHiromitsu KanamoriKeizo KanasakiChanhee KangRui KangSang Sun KangSenthilvelrajan KaniyappanTomotake KankiThirumala-Devi KannegantiAnumantha KanthasamyArthi KanthasamyMarc KantorowOrsolya KapuyMichalis KaramouzisMd. Razaul KarimParimal KarmakarRajesh KatareMasaru KatoStefan H.E. KaufmannAnu KauppinenGur KaushalSusmita KaushikKiyoshi KawasakiKemal KazanPo-Yuan KeDamien KeatingUrsula KeberJohn KehrlKate KellerChristian KellerJongsook Kim KemperCandia KenificOliver KeppStephanie KermorgantAndreas KernRobin KettelerTom KeulersBoris KhalfinHany KhalilBilon KhambuShahid KhanVinoth Kumar Megraj KhandelwalRekha KhandiaWiduri KhoNoopur KhobrekarSataree KhuansuwanMukhran KhundadzeSamuel KillackeyDasol KimDeok Ryong KimDo-Hyung KimDong-Eun KimEun Young KimEun-Kyoung KimHak-Rim KimHee-Sik KimHyung-Ryong KimJeong Hun KimJin Kyung KimJin-Hoi KimJoungmok KimJu Hwan KimKeun Il KimPeter KimSeong-Jun KimScot KimballAdi KimchiAlec KimmelmanTomonori KimuraMatthew KingKerri KinghornConan KinseyVladimir KirkinLorrie KirshenbaumSergey KiselevShuji KishiKatsuhiko KitamotoYasushi KitaokaKaio KitazatoRichard KitsisJosef KittlerOle KjaerulffPeter KleinThomas KlopstockJochen KluckenHelene KnævelsrudRoland KnorrBen C.B. KoFred KoJiunn-Liang KoHotaka KobayashiSatoru KobayashiIna KochJan KochUlrich KoenigDonat KögelYoung Ho KohMasato KoikeSepp KohlweinNur KocaturkMasaaki KomatsuJeannette KönigToru KonoBenjamin KoppTamas KorcsmarosGözde KorkmazViktor KorolchukMónica Suárez KorsnesAli KoskelaJanaiah KotaYaichiro KotakeMonica KotlerYanjun KouMichael KoukourakisEvangelos KoustasAttila KovacsTibor KovácsDaisuke KoyaTomohiro KozakoClaudine KraftDimitri KraincHelmut KrämerAnna KrasnodembskayaCarole Kretz-RemyGuido KroemerNicholas KtistakisKazuyuki KuchitsuSabine KuenenLars KuerschnerThomas KukarSaptaparna BhattacharyaAshok KumarDeepak KumarDhiraj KumarSharad KumarShinji KumeCaroline KumstaChanakya KunduMondira KunduAjaikumar KunnumakkaraLukasz KurganTatiana KutateladzeOzlem KutluSeongae KwakHo Jeong KwonTaeg Kyu KwonYong Tae KwonIrene KyrmiziAlbert La SpadaPatrick LabontéSylvain LadoireIlaria LafaceFrank LafontDiane LagaceVikramjit LahiriZhibing LaiAngela LairdAparna LakkarajuTrond LamarkSheng-Hui LanAne LandajuelaDarius LaneJon LaneCharles LangCarsten LangeÜlo LangelRupert LangerPierre LapaquetteJocelyn LaporteNicholas LarussoIsabel Lastres-BeckerWilson Chun Yu LauGordon LaurieSergio LavanderoBetty Yuen Kwan LawHelen Ka-Wai LawRob LayfieldWeidong LeHerve Le StunffAlexandre LearyJean-Jacques LebrunLionel Y.W. LeckJean-Philippe Leduc-GaudetChangwook LeeChung-Pei LeeDa-Hye LeeEdward LeeErinna LeeGyun Min LeeHe-Jin LeeHeung Kyu LeeJae Man LeeJason LeeJin-A LeeJoo-Yong LeeJun Hee LeeMichael LeeMin Goo LeeMin Jae LeeMyung-Shik LeeSang Yoon LeeSeung-Jae LeeStella LeeSung Bae LeeWon Hee LeeYing-Ray LeeYong-Ho LeeYoungil LeeChristophe LefebvreRenaud LegouisYu LeiYuchen LeiSergey LeikinGerd LeitingerLeticia LemusShuilong LengOlivia LenoirGuido LenzHeinz Josef LenzPaola LenziYolanda LeónAndréia LeopoldinoChristoph LeschczykStina LeskeläElisabeth LetellierChi-Ting LeungPo Sing LeungJeremy LeventhalBeth LevinePatrick LewisKlaus LeyBin LiDa-Qiang LiJianming LiJing LiJiong LiRobert Johannes LangenbergLiwu LiMei LiMin LiMing LiMingchuan LiPin-Lan LiMing-Qing LiQing LiSheng LiTiangang LiWei LiWenming LiXue LiYi-Ping LiYuan LiZhiqiang LiZhiyong LiZhiyuan LiJiqin LianChengyu LiangQiangrong LiangWeicheng LiangYongheng LiangYongtian LiangGuanghong LiaoLujian LiaoMingzhi LiaoYung-Feng LiaoMariangela LibrizziPearl LieMary LillyHyunjung LimThania R.R. LimaFederica LimanaChao LinChih-Wen LinDar-Shong LinFu-Cheng LinJiandie LinKurt LinKwang-Huei LinLiang-Tzung LinPei-Hui LinQiong LinShaofeng LinSu-Ju LinWenyu LinXueying LinYao-Xin LinYee-Shin LinRafael LindenPaula LindnerShuo-Chien LingPaul LingorAmelia LinnemannYih-Cherng LiouMarta LipinskiSaška LipovšekVitor LiraNatalia LisiakPaloma LitonChao LiuChing-Hsuan LiuChun-Feng LiuCui Hua LiuFang LiuHao LiuHsiao-Sheng LiuHua-Feng LiuHuifang LiuJia LiuJing LiuJulia LiuLeyuan LiuLonghua LiuMeilian LiuQin LiuYichen LiWende LiuXiao-Hong LiuXiaodong LiuXingguo LiuXu LiuXuedong LiuYanfen LiuYang LiuYueyang LiuYule LiuJ. Andrew LivingstonGerard LizardJose LizcanoSenka Ljubojevic-HolzerMatilde LleonartDavid Llobet-NavàsAlicia LlorenteChih Hung LoDamián Lobato-MárquezQi LongYun Chau LongBen LoosJulia LoosManuela LópezGuillermo López-DoménechJosé Antonio López-GuerreroAna López-JiménezÓscar López-PérezIsrael López-ValeroMagdalena LorenowiczMar LorentePeter LorinczLaura LossiSophie LotersztajnPenny LovatJonathan LovellAlenka LovyPéter LőwGuang LuHaocheng LuJia-Hong LuJin-Jian LuMengji LuShuyan LuAlessandro LucianiJohn LucocqPaula LudovicoMicah LuftigMorten LuhrDiego Luis-RaveloJulian LumLiany Luna-DulceyAnders LundViktor LundJan LünemannPatrick LüningschrörHonglin LuoRongcan LuoShouqing LuoZhi LuoClaudio LuparelloBernhard LüscherLuan LuuAlex LyakhovichKonstantin LyamzaevAlf Håkon LystadLyubomyr LytvynchukAlvin MaChangle MaMengxiao MaNing-Fang MaQuan-Hong MaXinliang MaYueyun MaZhenyi MaOrmond MacdougaldFernando MacianGustavo MacintoshJeffrey MackeiganKay MacleodSandra MadayFrank MadeoMuniswamy MadeshTobias MadlJulio Madrigal-MatuteAkiko MaedaYasuhiro MaejimaMarta MagarinosPoornima MahavadiEmiliano MaianiKenneth MaiesePanchanan MaitiMaria Chiara MaiuriBarbara MajelloMichael MajorElena MakareevaFayaz MalikKarthik MallilankaramanWalter MalorniAlina MaloyanNajiba MammadovaGene Chi Wai ManFederico ManaiJoseph ManciasEva-Maria MandelkowMichael MandellAngelo ManfrediMasoud ManjiliRavi ManjithayaPatricio ManqueBella ManshianRaquel ManzanoClaudia ManzoniKai MaoCinzia MarcheseSandrine MarchettiAnna Maria MarconiFabrizio MarcucciStefania MardenteOlga MareninovaMarta MargetaMuriel MariSara MarinelliOliviero MarinelliGuillermo MariñoSofia MariottoRichard MarshallMark MartenSascha MartensAlexandre P.J. MartinKatie MartinSara MartinShaun MartinAdrián Martín-SeguraMiguel Martín-AcebesInmaculada Martin-BurrielMarcos Martin-RinconPaloma Martin-SanzJosé MartinaWim MartinetAitor MartinezAna MartinezJennifer MartinezMoises Martinez VelazquezNuria Martinez-LopezMarta Martinez-VicenteDaniel MartinsJoilson MartinsWaleska MartinsTania Martins-MarquesEmanuele MarzettiShashank MasaldanCéline Masclaux‐daubresseDouglas MashekValentina MassaLourdes MassieuGlenn MassonLaura MasuelliAnatoliy MasyukTetyana MasyukPaola MatarreseAnder MatheuSatoaki MatobaSachiko MatsuzakiPamela MattarAlessandro MatteDomenico MattoscioJosé MaurizMario MautheCaroline MauvezinEmanual MaverakisPaola MaycotteJohanna MayerGianluigi MazzoccoliCristina MazzoniJoseph MazzulliNami MccartyChristine McdonaldMitchell McgillSharon MckennaBethann MclaughlinFionn McloughlinMark McnivenThomas McwilliamsFatima Mechta-GrigoriouTania Catarina MedeirosDiego MedinaLynn MegeneyKlara MegyeriMaryam MehrpourJawahar MehtaAlfred MeijerAnnemarie MeijerJakob MejlvangAlicia MeléndezAnnette MelkGonen MemisogluAlexandrina MendesDelong MengFei MengTian MengRubem Menna-BarretoManoj MenonCarol MercerAnne MercierJean‐louis MergnyAdalberto MerighiSeth MerkleyGiuseppe MerlaVolker MeskeAna Cecilia MestreShree Padma MeturChristian MeyerHemmo MeyerWenyi MiJeanne Mialet-PerezJunying MiaoLucia MicaleYasuo MikiEnrico MilanMałgorzata MilczarekDana MillerSamuel MillerSilke MillerSteven MillwardIra MilosevicElena MininaHamed MirzaeiHamid Reza MirzaeiMehdi MirzaeiAmit MishraNandita MishraParas Kumar MishraMaja Misirkic MarjanovicRoberta MisasiAmit MisraGabriella MissoClaire MitchellGeraldine MitouTetsuji MiuraShigeki MiyamotoMakoto MiyazakiMitsunori MiyazakiTaiga MiyazakiKeisuke MiyazawaNoboru MizushimaTrine Hyrup MogensenBaharia MograbiReza MohammadinejadYasir MohamudAbhishek MohantySipra MohapatraTorsten MöhlmannAsif MohmmedAnna MolesKelle MoleyMaurizio MolinariVincenzo MollaceAndreas Buch MøllerBertrand MollereauFaustino MollinedoCostanza MontagnaMervyn MonteiroAndrea MontellaL. Ruth MontesBarbara MonticoVinod MonyGiacomo Monzio CompagnoniMichael MooreMohammad MoosaviAna MoraMarina MoraDavid Morales-AlamoRosario MoratallaPaula MoreiraElena MorelliSandra MorenoDaniel Moreno-BlasViviana MoresiBenjamin MorgaAlwena MorganFabrice MorinHideaki MorishitaOrson MoritzMariko MoriyamaYuji MoriyasuManuela MorleoEugenia MorselliJose Moruno-ManchonJorge MoscatSerge MostowyElisa MotoriAndrea Felinto MouraNaima Moustaid-MoussaMaria MrakovcicGabriel Muciño-HernándezAnupam MukherjeeSubhadip MukhopadhyayJean Mulcahy LevyVictoriano MuleroSylviane MullerChristian MünchAshok MunjalPura Munoz-CanovesTeresa Muñoz-GaldeanoChristian MünzTomokazu MurakawaClaudia MuratoriBrona MurphyJ. Patrick MurphyAditya MurthyTimo MyöhänenIndira MysorekarJennifer MytychSeyed Mohammad NabaviMassimo NabissiPéter NagyJihoon NahAimable NahimanaIchiro NakagawaKen NakamuraHitoshi NakatogawaShyam NandiMeera NanjundanMonica NanniGennaro NapolitanoRoberta NardacciMasashi NaritaMelissa NassifIlana NathanManabu NatsumedaRyno NaudeChristin NaumannOlaia NaveirasFatemeh NavidSteffan NawrockiTaras NazarkoFrancesca NazioFlorentina NegoitaThomas NeillAmanda NeischLuca NeriMihai NeteaPatrick NeubertThomas NeufeldDietbert NeumannAlbert NeutznerPhillip NewtonPaul NeyIoannis NezisCharlene C.W. NgTzi Bun NgHang NguyenLong NguyenHong-Min NiClíona Ní CheallaighZhenhong NiM. Celeste NicolaoFrancesco NicoliManuel Nieto-DiazPer NilssonShunbin NingRituraj NiranjanHiroshi NishimuneMireia Niso-SantanoRalph NixonAnnalisa NobiliClevio NobregaTakeshi NodaUxía Nogueira-RecaldeTrevor NolanIvan NombelaIvana NovakBeatriz NovoaTakashi NozawaNobuyuki NukinaCarmen Nussbaum-KrammerJesper NylandstedTracey O’donovanSeónadh O’learyEyleen O’rourkeMary O’sullivanTimothy O’sullivanSalvatore OddoIna OehmeMichinaga OgawaEric Ogier-DenisMargret OgmundsdottirBesim OgretmenGoo Taeg OhSeon-Hee OhYoung OhTakashi OhamaYohei OhashiMasaki OhmurayaVasileios OikonomouRani OjhaKoji OkamotoHitoshi OkazawaMasahide OkuSara OlivánJorge OliveiraMichael OllmannJames OlzmannShakib OmariM. Bishr OmaryGizem ÖnalMartin OndrejSang-Bing OngSang-Ging OngAnna OnnisJuan OrellanaSara Orellana-MuñozMaria del Mar Ortega-VillaizanXilma Ortiz-GonzalezElena OrtonaHeinz OsiewaczAbdel-Hamid OsmanRosario OstaMarisa OteguiKinya OtsuChristiane OttLuisa OttobriniJing-Hsiung James OuTiago OuteiroInger OynebratenMelek OzturkGilles PagèsSusanta PahariMarta PajaresUtpal PajvaniRituraj PalSimona PaladinoNicolas PalletMichela PalmieriGiuseppe PalmisanoCamilla PalumboFrancesco PampaloniLifeng PanQingjun PanWenliang PanXin PanGanna PanasyukRahul PandeyUdai PandeyVrajesh PandyaFrancesco PaneniShirley PangElisa PanzariniDaniela PapademetrioElena PapaleoDaniel PapinskiDiana PappEun Chan ParkHwan Tae ParkJi-Man ParkJong-In ParkJoon Tae ParkJunsoo ParkSang Chul ParkSang-Youel ParkAbraham ParolaJan ParysAdrien PasquierBenoit PasquierJoão PassosNunzia PastoreHemal PatelDaniel PatschanSophie PattingreGustavo Pedraza-AlvaJose Pedraza-ChaverriZully PedrozoGang PeiJianming PeiHadas Peled-ZehaviJoaquín PellegriniJoffrey PelletierMiguel PeñalvaDi PengYing PengFabio PennaMaria PennutoFrancesca PentimalliCláudia Mf PereiraGustavo J.S. PereiraLilian PereiraLuis Pereira de AlmeidaNirma PereraÁngel Pérez-LaraAna Perez-OlivaMaría Esther Pérez-PérezPalsamy PeriyasamyAndras PerlCristiana PerrottaIda PerrottaRichard PestellMorten PetersenIrina PetracheGoran PetrovskiThorsten PfirrmannAstrid PfisterJennifer PhilipsHuifeng PiAnna PiccaAlicia PickrellSandy PicotGiovanna PierantoniMarina PierdominiciPhilippe PierreValérie Pierrefite-CarleKarolina PierzynowskaFederico PietrocolaMiroslawa PietruczukClaudio PignataFelipe Pimentel-MuiñosMario PinarRoberta PinheiroRonit Pinkas-KramarskiPaolo PintonKarolina PircsSujan PiyaPaola PizzoTheo PlantingaHarald PlattaAinhoa Plaza-ZabalaMarkus PlomannEgor PlotnikovHelene Plun-FavreauRyszard PlutaRoger PocockStefanie PöggelerChristian PohlM PoirotAngelo PolettiMarisa PonpuakHana PopelkaBlagovesta PopovaHelena PortaSoledad Porte AlconEliana Portilla-FernandezMartin PostMalia PottsJoanna PoultonTed PowersVeena PrahladTomasz K. PrajsnarDomenico PraticòRosaria PrencipeMuriel PriaultTassula Proikas-CezanneVasilis J. PromponasChristopher G. ProudRosa PuertollanoLuigi PuglielliThomas PulinilkunnilDeepika PuriRajat PuriJulien PuyalXiaopeng QiYongmei QiWenbin QianLei QiangYu QiuJoe QuadrilateroJorge QuarleriNina RabenHannah RabinowichDebora RagonaMichael J. RagusaNader RahimiMarveh RahmatiValeria RaiaNuno RaimundoNamakkal-Soorappan RajasekaranSriganesh Ramachandra RaoAbdelhaq RamiIgnacio Ramírez-PardoDavid B. RamsdenFelix RandowPundi N. RangarajanDanilo RanieriHai RaoLang RaoRekha RaoSumit RathoreJ. Arjuna RatnayakaEdward A. RatovitskiPalaniyandi RavananGloria RavegniniSwapan K. RayBabak RazaniVito RebeccaFulvio ReggioriAnne Régnier-VigourouxAndreas S. ReichertDavid ReigadaJan H. ReilingTheo ReinSiegfried ReipertRokeya Sultana RekhaHongmei RenJun RenWeichao RenTristan RenaultGiorgia RengaKaren ReueKim RewitzBruna Ribeiro de Andrade RamosS. Amer RiazuddinTeresa M. Ribeiro-RodriguesJean-Ehrland RicciRoméo RicciVictoria RiccioDes R. RichardsonYasuko RikihisaMakarand V. RisbudRuth M. RisueñoKonstantinos RitisSalvatore RizzaRosario RizzutoHelen C. RobertsLuke D. RobertsKatherine J. RobinsonMaria Carmela RoccheriStephane RocchiGeorge G. RodneyTiago RodriguesVagner Ramon Rodrigues SilvaAmaia RodriguezRuth Rodriguez-BarruecoNieves Rodriguez-HencheHumberto Rodriguez-RochaJeroen RoelofsRobert S. RogersVladimir V. RogovAna I. RojoKrzysztof RolkaVanina RomanelloLuigina RomaniAlessandra RomanoPatricia S. RomanoDavid Romeo-GuitartLuis C. RomeroMontserrat RomeroJoseph C. RoneyChristopher RongoSante RopertoMathias T. RosenfeldtPhilip RosenstielAnne G. RosenwaldKevin A. RothLynn RothSteven RothKasper M.A. RouschopBenoit D. RousselSophie RouxPatrizia Rovere-QueriniAjit RoyAurore RozieresDiego RuanoDavid C. RubinszteinMaria P. RubtsovaKlaus RuckdeschelChristoph RuckenstuhlEmil RudolfRüdiger RudolfAlessandra RuggieriAvnika Ashok RupareliaPaola RusminiRyan R. 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SharkeyDipali SharmaGaurav SharmKulbhushan SharmaPawan SharmaSurendra SharmaHan-Ming ShenHongtao ShenJiangang ShenMing ShenWeili ShenZheni ShenRui ShengZhi ShengZu-Hang ShengJianjian ShiXiaobing ShiYing-Hong ShiKahori Shiba-FukushimaJeng-Jer ShiehYohta ShimadaShigeomi ShimizuMakoto ShimozawaTakahiro ShintaniChristopher J. ShoemakerShahla ShojaeiIkuo ShojiBhupendra V. ShravageViji ShridharChih-Wen ShuHong-Bing ShuKe ShuiArvind K. ShuklaTimothy E. ShuttValentina SicaAleem SiddiquiAmanda SierraVirginia Sierra-TorreSantiago SignorelliPayel SilBruno J. de Andrade SilvaJohnatas D. SilvaEduardo Silva-PavezSandrine Silvente-PoirotRachel E. SimmondsAnna Katharina SimonHans-Uwe SimonMatias SimonsAnurag SinghLalit P. SinghRajat SinghShivendra V. SinghShrawan K. SinghSudha B. SinghSunaina SinghSurinder Pal SinghDebasish SinhaRohit Anthony SinhaSangita SinhaAgnieszka SirkoKapil SirohiEfthimios L. SivridisPanagiotis SkendrosAleksandra SkiryczIva SlaninováSoraya S. SmailiAndrei SmertenkoMatthew D. SmithStefaan J. SoenenEun Jung SohnSophia P. M. SokGiancarlo SolainiThierry SoldatiScott A. SoleimanpourRosa M. SolerAlexei SolovchenkoJason A. SomarelliAvinash SonawaneFuyong SongHyun Kyu SongJu-Xian SongKunhua SongZhiyin SongLeandro R. SoriaMaurizio SoriceAlexander A. SoukasSandra-Fausia SoukupDiana SousaNadia SousaPaul A. SpagnuoloStephen A. SpectorM. M. Srinivas BharathDaret St. ClairVenturina StagniLeopoldo StaianoClint A. StalneckerMetodi V. StankovPeter B. StathopulosKatja StefanSven Marcel StefanLeonidas StefanisJoan S. SteffanAlexander SteinkassererHarald StenmarkJared SterneckertCraig StevensVeronika StokaStephan StorchBjörn StorkFlavie StrappazzonAnne Marie StroheckerDwayne G. StupackHuanxing SuLing-Yan SuLongxiang SuAna M. Suarez-FontesCarlos S. SubausteSelvakumar SubbianPaula V. SubiradaGanapasam SudhandiranCarolyn M. SueXinbing SuiCorey SummersGuangchao SunJun SunKang SunMeng-Xiang SunQiming SunYi SunZhongjie SunKaren K.S. SunaharaEva SundbergKatalin SusztakPeter SutovskyHidekazu SuzukiGary SweeneyJ. David SymonsStephen Cho Wing SzeNathaniel J. SzewczykAnna Tabęcka-ŁonczynskaClaudio TabolacciFrank TackeHeinrich TaegtmeyerMarco TafaniMitsuo TagayaHaoran TaiStephen W. G. TaitYoshinori TakahashiSzabolcs TakatsPriti TalwarChit TamShing Yau TamDavide TampelliniAtsushi TamuraChong Teik TanEng-King TanYa-Qin TanMasaki TanakaMotomasa TanakaDaolin TangJingfeng TangTie-Shan TangIsei TanidaZhipeng TaoMohammed TaouisLars TatenhorstNektarios TavernarakisAllen TaylorGregory A. TaylorJoan M. TaylorElena TchetinaAndrew R. TeeIrmgard TegederDavid TeisNatercia TeixeiraFatima Teixeira-ClercKumsal A. TekirdagTewin TencomnaoSandra TenreiroAlexei V. TepikinPilar S. TestillanoGianluca TettamantiPierre-Louis TharauxKathrin ThedieckArvind A. ThekkinghatStefano ThellungJosephine W. ThinwaV. P. ThirumalaikumarSufi Mary ThomasPaul G. 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VahsenHelin Vakifahmetoglu-NorbergRut ValdorMaria J. ValenteAyelén ValkoRichard B. ValleeAngela M. ValverdeGreet van den BergheStijn van der VeenLuc van KaerJorg van LoosdregtSjoerd J.L. van WijkWim VandenbergheIlse VanhorebeekMarcos A. Vannier-SantosNicola VanniniM. Cristina VanrellChiara VantaggiatoGabriele VaranoIsabel Varela-NietoMáté VargaM. Helena VasconcelosSomya VatsDemetrios G. VavvasIgnacio Vega-NaredoSilvia Vega-Rubin-De-CelisGuillermo VelascoAriadna P. VelázquezTibor VellaiEdo VellengaFrancesca VelottiMireille VerdierPanayotis VerginisIsabelle VergnePaul VerkadeManish VermaPatrik VerstrekenTim VervlietJörg VervoortsAlexandre T. VessoniVictor M. VictorMichel VidalChiara VidoniOtilia V. VieiraRichard D. VierstraSonia ViganóHelena VihinenVinoy VijayanMiquel VilaMarçal VilarJosé M. VillalbaAntonio VillaloboBeatriz Villarejo-ZoriFrancesc VillarroyaJoan VillarroyaOlivier VincentCecile VindisChristophe ViretMaria Teresa ViscomiDora VisnjicIlio VitaleDavid J. VocadloOlga V. VoitsekhovskajaCinzia VolontéMattia VoltaMarta VomeroClarissa von HaefenMarc A. VooijsWolfgang VoosLjubica VucicevicRichard Wade-MartinsSatoshi WaguriKenrick A. WaiteShuji WakatsukiDavid W. WalkerMark J. WalkerSimon A. WalkerJochen WalterFrancisco G. WandosellBo WangChao-Yung WangChen WangChenran WangChenwei WangCun-Yu WangDong WangFangyang WangFeng WangFengming WangGuansong WangHan WangHao WangHexiang WangHong-Gang WangJianrong WangJigang WangJiou WangJundong WangKui WangLianrong WangLiming WangMaggie Haitian WangMeiqing WangNanbu WangPengwei WangPeipei WangPing WangPing WangQing Jun WangQing WangQing Kenneth WangQiong A. WangWen-Tao WangWuyang WangXinnan WangXuejun WangYan WangYanchang WangYanzhuang WangYen-Yun WangYihua WangYipeng WangYu WangYuqi WangZhe WangZhenyu WangZhouguang WangGary WarnesVerena WarnsmannHirotaka WatadaEizo WatanabeMaxinne WatchonAnna WawrzyńskaTimothy E. WeaverGrzegorz WegrzynAnn M. WehmanHuafeng WeiLei WeiTaotao WeiYongjie WeiOliver H. WeiergräberConrad C. WeihlGünther WeindlRalf WeiskirchenAlan WellsRunxia H. WenXin WenAntonia WernerBeatrice WeykopfSally P. WheatleyJ. Lindsay WhittonAlexander J. WhitworthKatarzyna WiktorskaManon E. WildenbergTom WilemanSimon WilkinsonDieter WillboldBrett WilliamsRobin S. B. WilliamsRoger L. WilliamsPeter R. WilliamsonRichard A. WilsonBeate WinnerNathaniel J. WinsorSteven S. WitkinHarald WodrichUte WoehlbierThomas WollertEsther WongJack Ho WongRichard W. WongVincent Kam Wai WongW. Wei-Lynn WongAn-Guo WuChengbiao WuJian WuJunfang WuKenneth K. WuMin WuShan-Ying WuShengzhou WuShu-Yan WuShufang WuWilliam K.K. WuXiaohong WuXiaoqing WuYao-Wen WuYihua WuRamnik J. XavierHongguang XiaLixin XiaZhengyuan XiaGe XiangJin XiangMingliang XiangWei XiangBin XiaoGuozhi XiaoHengyi XiaoHong-Tao XiaoJian XiaoLan XiaoShi XiaoYin XiaoBaoming XieChuan-Ming XieMin XieYuxiang XieZhiping XieZhonglin XieMaria XilouriCongfeng XuEn XuHaoxing XuJing XuJinrong XuLiang XuWen Wen XuXiulong XuYu XueSokhna M.S. Yakhine-DiopMasamitsu YamaguchiOsamu YamaguchiAi YamamotoShunhei YamashinaShengmin YanShian-Jang YanZhen YanYasuo YanagiChuanbin YangDun-Sheng YangHuan YangHuang-Tian YangHui YangJin-Ming YangJing YangJingyu YangLing YangLiu YangMing YangPei-Ming YangQian YangSeungwon YangShu YangShun-Fa YangWannian YangWei Yuan YangXiaoyong YangXuesong YangYi YangYing YangHonghong YaoShenggen YaoXiaoqiang YaoYong-Gang YaoYong-Ming YaoTakahiro YasuiMeysam YazdankhahPaul M. YenCong YiXiao-Ming YinYanhai YinZhangyuan YinZiyi YinMeidan YingZheng YingCalvin K. YipStephanie Pei Tung YiuYoung H. YooKiyotsugu YoshidaSaori R. YoshiiTamotsu YoshimoriBahman YousefiBoxuan YuHaiyang YuJun YuJun YuLi YuMing-Lung YuSeong-Woon YuVictor C. YuW. Haung YuZhengping YuZhou YuJunying YuanLing-Qing YuanShilin YuanShyng-Shiou F. YuanYanggang YuanZengqiang YuanJianbo YueZhenyu YueJeanho YunRaymond L. YungDavid N. ZacksGabriele ZaffagniniVanessa O. ZambelliIsabella ZanellaQun S. ZangSara ZanivanSilvia ZappavignaPilar ZaragozaKonstantinos S. ZarbalisAmir ZarebkohanAmira ZarroukScott O. ZeitlinJialiu ZengJu-Deng ZengEva ŽerovnikLixuan ZhanBin ZhangDonna D. ZhangHanlin ZhangHong ZhangHong ZhangHonghe ZhangHuafeng ZhangHuaye ZhangHui ZhangHui-Ling ZhangJianbin ZhangJianhua ZhangJing-Pu ZhangKalin Y.B. ZhangLeshuai W. ZhangLin ZhangLisheng ZhangLu ZhangLuoying ZhangMenghuan ZhangPeng ZhangSheng ZhangWei ZhangXiangnan ZhangXiao-Wei ZhangXiaolei ZhangXiaoyan ZhangXin ZhangXinxin ZhangXu Dong ZhangYang ZhangYanjin ZhangYi ZhangYing-Dong ZhangYingmei ZhangYuan-Yuan ZhangYuchen ZhangZhe ZhangZhengguang ZhangZhibing ZhangZhihai ZhangZhiyong ZhangZili ZhangHaobin ZhaoLei ZhaoShuang ZhaoTongbiao ZhaoXiao-Fan ZhaoYing ZhaoYongchao ZhaoYongliang ZhaoYuting ZhaoGuoping ZhengKai ZhengLing ZhengShizhong ZhengXi-Long ZhengYi ZhengZu-Guo ZhengBoris ZhivotovskyQing ZhongAo ZhouBen ZhouCefan ZhouGang ZhouHao ZhouHongbo ZhouJie ZhouJing ZhouJing ZhouJiyong ZhouKailiang ZhouRongjia ZhouXu-Jie ZhouYanshuang ZhouYinghong ZhouYubin ZhouZheng-Yu ZhouZhou ZhouBinglin ZhuChanglian ZhuGuo-Qing ZhuHaining ZhuHongxin ZhuHua ZhuWei-Guo ZhuYanping ZhuYushan ZhuHaixia ZhuangXiaohong ZhuangKatarzyna Zientara-RytterChristine M. ZimmermannElena ZivianiTeresa ZoladekWei-Xing ZongDmitry B. ZorovAntonio ZorzanoWeiping ZouZhen ZouZhengzhi ZouSteven ZurynWerner ZwerschkeBeate Brand-SaberiX. Charlie DongChandra Shekar KenchappaZuguo LiYong LinShigeru OshimaYueguang RongJudith C. SluimerChristina L. StallingsChun-Kit Tong
• Organismes : Université du Michigan = University of Michigan [Ann Arbor] Institut Pasteur d'Iran The Arctic University of Norway [Tromsø, Norway] Institut de pharmacologie moléculaire et cellulaire Lipides - Nutrition - Cancer [Dijon - U1231] Centre de Recherches sur la Cognition Animale - UMR5169 Centre de Biologie Intégrative Centre méditerranéen de médecine moléculaire Institut de Biologie Valrose Maladies et hormones du système nerveux University of South Carolina Upstate Centre de Recherche des Cordeliers The Francis Crick Institute [London] Royal Free Hospital [London, UK] Physiologie et physiopathologie endocriniennes Nutrition, Métabolisme, Aquaculture Laboratoire de Biologie Moléculaire et Cellulaire des Eucaryotes Department of Molecular Medicine Biotechnologie et signalisation cellulaire Institut Cochin Laboratoire de biogenèse membranaire Université du Québec à Trois-Rivières Laboratory of Pathogen Host Interactions [Montpellier] Physiologie et physiopathologie endocriniennes Institut NeuroMyoGène Centre de Recherche des Cordeliers Paris-Centre de Recherche Cardiovasculaire Marqueurs cardiovasculaires en situation de stress Centre de Recherche des Cordeliers Institut de Recherche sur le Cancer et le Vieillissement OEil, nutrition et signalisation cellulaire [CSGA] Biologie des Bactéries intracellulaires - Biology of Intracellular Bacteria Institut Curie [Paris] Institut de biochimie et génétique cellulaires Transporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux Transporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux Centre de Recherche en Cancérologie de Marseille Laboratoire d'ingénierie des systèmes macromoléculaires Métabolisme, Cancer et Immunité Plateforme de métabolomique Institut de pharmacologie moléculaire et cellulaire Centre for Integrative Biology Institut de pharmacologie moléculaire et cellulaire Chemistry, Oncogenesis, Stress and Signaling CRLCC Eugène Marquis Institut Necker Enfants-Malades Laboratoire de Biologie Moléculaire et Cellulaire des Eucaryotes Unité de Nutrition Humaine Institut de Biologie Intégrative de la Cellule Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte Institut des Maladies Neurodégénératives [Bordeaux] Centre de Recherche des Cordeliers Institut de Recherche en Infectiologie de Montpellier Centre International de Recherche en Infectiologie Centre de Recherches en Cancérologie de Toulouse Maladies et hormones du système nerveux Laboratoire de biogenèse membranaire Laboratoire de Physiologie et Génomique des Poissons = Fish Physiology and Genomics Institute Centre de Recherche en Cancérologie de Marseille Physiopathologie et traitement des maladies du foie Centre de Recherches en Cancérologie de Toulouse Institut Cochin Centre de Recherche des Cordeliers Plateforme de métabolomique Institut NeuroMyoGène Centre de Recherche des Cordeliers Plateforme de métabolomique Hôpital Européen Georges Pompidou [APHP] Karolinska Institutet [Stockholm] Armand-Frappier Santé Biotechnologie Research Centre Département d'oncologie médicale [Centre Georges-François Leclerc] Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 Procédés Alimentaires et Microbiologiques [Dijon] Institut de Génétique et de Biologie Moléculaire et Cellulaire Institut des Neurosciences Paris-Saclay Paris-Centre de Recherche Cardiovasculaire Laboratoire Bio-PeroxIL. Biochimie du peroxysome, inflammation et métabolisme lipidique [Dijon] Centre de recherche sur l'Inflammation Centre de Recherche des Cordeliers Centre méditerranéen de médecine moléculaire Institut Jean-Pierre Bourgin - Sciences du végétal CHU Clermont-Ferrand Institut Pascal Unité de génétique et biologie des cancers Biologia Celular [Rio de Janeiro] Laboratoire d'Optique et Biosciences Institut Jean-Pierre Bourgin - Sciences du végétal Institut des Maladies Métaboliques et Cardiovasculaires Institut des Maladies Métaboliques et Casdiovasculaires Université Toulouse III - Paul Sabatier Institut de Recherche sur le Cancer et le Vieillissement Centre de Lutte contre le Cancer Antoine Lacassagne [Nice] Laboratoire de biologie et modélisation de la cellule Unité Santé, Génétique et Microbiologie des Mollusques Différenciation et communication neuronale et neuroendocrine Biotechnologie et signalisation cellulaire Institut d’Etudes Avancées de l’Université de Strasbourg - Institute for Advanced Study Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte Centre de recherche sur l'Inflammation Centre de Recherche des Cordeliers Sanofi [Vitry-sur-Seine] Institut de Recherche en Cancérologie de Montpellier UNICANCER - Institut régional du Cancer Montpellier Val d'Aurelle Unité Santé, Génétique et Microbiologie des Mollusques Centre d'Immunologie de Marseille - Luminy Universidade de Aveiro = University of Aveiro Shanghai Jiao Tong University [Shanghai] Transporteurs et Imagerie, Radiothérapie en Oncologie et Mécanismes biologiques des Altérations du Tissu Osseux Centre de Recherches en Cancérologie de Toulouse Institut de Génétique et de Biologie Moléculaire et Cellulaire Laboratory of Fundamental and Applied Bioenergetics = Laboratoire de bioénergétique fondamentale et appliquée Institut de pharmacologie et de biologie structurale Laboratory of Pathogen Host Interactions [Montpellier] Biochimie membranaire et transport / Membrane Biochemistry and Transport
• Publié dans Autophagy le 02/11/2020

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Résumé : In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.

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Fichiers liés : Klionsky Guidelines 2021 (1).pdf

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