Philippe JEAN-PIERRE

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : John B WhitfieldS MassonSuthat LiangpunsakulSebastian MuellerGuruprasad P AithalFlorian EyerDermot GleesonA ThompsonFelix StickelMichael SoykaAnn K DalyHeather J CordellTatiana ForoudLawrence LumengMunir PirmohamedBertrand NalpasJean-Marc JacquetRomain MoirandPierre NahonSylvie S. NaveauPascal PerneyPaul S HaberHervé SeitzC DayPhilippe MathurinTimothy R MorganDevanshi Seth
• Organismes : QIMR Berghofer Medical Research Institute Newcastle University [Newcastle] Indiana University System Universität Heidelberg [Heidelberg] = Heidelberg University University of Nottingham, UK Technische Universität Munchen = Technical University Munich = Université Technique de Munich Royal Hallamshire Hospital University of Liverpool University hospital of Zurich [Zurich] University-Hospital Munich-Großhadern [München] Newcastle University [Newcastle] Newcastle University [Newcastle] Indiana University School of Medicine Indiana University System University of Liverpool Hôpital Universitaire Carémeau [Nîmes] Hôpital Universitaire Carémeau [Nîmes] Nutrition, Métabolismes et Cancer Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Génomique Fonctionnelle des Tumeurs Solides Hôpital Jean Verdier [AP-HP] AP-HP - Hôpital Antoine Béclère [Clamart] Hôpital Universitaire Carémeau [Nîmes] The University of Sydney Universität Heidelberg [Heidelberg] = Heidelberg University Newcastle University [Newcastle] Centre Hospitalier Régional Universitaire [CHU Lille] California State University [Long Beach] University of California The University of Sydney
• Publié dans The American Journal of Gastroenterology le 22/10/2020

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Résumé : Introduction - Sustained high alcohol intake is necessary but not sufficient to produce alcohol-related cirrhosis. Identification of risk factors, apart from lifetime alcohol exposure, would assist in discovery of mechanisms and prediction of risk. Methods - We conducted a multicenter case-control study (GenomALC) comparing 1,293 cases (with alcohol-related cirrhosis, 75.6% male) and 754 controls (with equivalent alcohol exposure but no evidence of liver disease, 73.6% male). Information confirming or excluding cirrhosis, and on alcohol intake and other potential risk factors, was obtained from clinical records and by interview. Case-control differences in risk factors discovered in the GenomALC participants were validated using similar data from 407 cases and 6,573 controls from UK Biobank. Results - The GenomALC case and control groups reported similar lifetime alcohol intake (1,374 vs 1,412 kg). Cases had a higher prevalence of diabetes (20.5% (262/1,288) vs 6.5% (48/734), P = 2.27 × 10) and higher premorbid body mass index (26.37 ± 0.16 kg/m) than controls (24.44 ± 0.18 kg/m, P = 5.77 × 10). Controls were significantly more likely to have been wine drinkers, coffee drinkers, smokers, and cannabis users than cases. Cases reported a higher proportion of parents who died of liver disease than controls (odds ratio 2.25 95% confidence interval 1.55-3.26). Data from UK Biobank confirmed these findings for diabetes, body mass index, proportion of alcohol as wine, and coffee consumption. Discussion - If these relationships are causal, measures such as weight loss, intensive treatment of diabetes or prediabetic states, and coffee consumption should reduce the risk of alcohol-related cirrhosis.

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Fichiers liés : Whitfield et al. - 2021 - Obesity, Diabetes, Coffee, Tea, and Cannabis Use A.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Mathieu ChalouniStanislas PolPhilippe SogniHélène FontaineKarine LacombeJean Marc-LacombeLaure EsterleCeline DorivalMarc BourlièreFirouzé Bani-SadrVictor de LedinghenDavid ZucmanDominique LarreyDominique Salmon-CéronFabrice CarratLinda Wittkop
• Organismes : Team MORPH3EUS CIC Bordeaux Immunité Innée - Innate Immunity Hôpital Cochin [AP-HP] Immunité Innée - Innate Immunity Hôpital Cochin [AP-HP] Immunité Innée - Innate Immunity Hôpital Cochin [AP-HP] Institut Pierre Louis d'Epidémiologie et de Santé Publique CHU Saint-Antoine [AP-HP] INSERM-TRANSFERT [Paris] Team MORPH3EUS Institut Pierre Louis d'Epidémiologie et de Santé Publique Hôpital Saint-Joseph [Marseille] Hôpital universitaire Robert Debré [Reims] Bordeaux Research In Translational Oncology [Bordeaux] Hôpital Haut-Lévêque [CHU Bordeaux] Hôpital Foch [Suresnes] Hôpital Saint-Éloi [Montpellier] Hôpital Cochin [AP-HP] Hôpital Hôtel-Dieu [Paris] Université Paris Cité Institut Pierre Louis d'Epidémiologie et de Santé Publique CHU Saint-Antoine [AP-HP] Institut de Santé Publique, d'Epidémiologie et de Développement Team MORPH3EUS CIC Bordeaux
• Publié dans Journal of Hepatology le 23/10/2020

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Résumé : Background & aims: Direct-acting antivirals (DAA) lead to high sustained virological response (SVR) rates and decrease the risk of disease progression. We compared SVR rates and all-cause, liver- and non-liver-related deaths, liver-related events, and non-liver-related cancers in HIV/HCV-coinfected and HCV-monoinfected participants from 2 French cohort studies after initiation of DAA treatment. Methods: Up to 4 HCV-monoinfected participants from the ANRS CO22 HEPATHER cohort were matched by age and sex to each HIV/HCV-coinfected patient from the ANRS CO13 HEPAVIH cohort; both are nationwide, prospective, multicentre, and observational. Participants were initiated on DAAs between March 2014 and December 2017. Cox proportional hazards models adjusted by age, sex, duration since HCV diagnosis, HCV transmission routes, HCV genotypes, cirrhosis, tobacco, alcohol consumption, and SVR (time dependent) were used. Results: A total of 592 HIV/HCV-coinfected and 2,049 HCV-monoinfected participants were included; median age was 53.3 years (inter-quartile range: 49.6-56.9) and 52.9 years (49.6; 56.7), 1,498 (73.1%) and 436 (73.6%) were men, and 159 (28.8%) and 793 (41.2%) had cirrhosis, respectively. SVR was observed in 92.9% and 94.6%, respectively. HIV coinfection was associated with higher risk of all-cause death (hazard ratio [HR] 1.93; 95% CI 1.01-3.69), non-liver-related death (HR 2.84; 95% CI 1.27-6.36), and non-liver-related cancer (HR 3.26; 95% CI 1.50-7.08), but not with liver-related-death (HR 1.04; 95% CI 0.34-3.15) or liver-related events (HR 0.66; 95% CI 0.31-1.44). Conclusions: After DAA treatment, HIV-coinfected individuals had similar SVR rates and risk of liver-related deaths and events compared with HCV-monoinfected individuals, but had a higher risk of all-cause and non-liver-related deaths and non-liver-related cancers. Lay summary: We compared the risk of several clinical events in participants infected by human immunodeficiency virus and hepatitis C virus with those infected with hepatitis C virus alone, matched on age and sex, after treatment with contemporary direct-acting antivirals. We found a higher risk of all-cause deaths, non-liver-related deaths, and non-liver-related cancers in participants coinfected with the human immunodeficiency virus and hepatitis C virus, and no differences for the risk of liver-related deaths or events. Trial registration: ClinicalTrials.gov NCT03324633 NCT01953458.

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Fichiers liés : inserm-03332406.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Sophie MathaisXavier MoissetBruno PereiraFrederic TaitheJonathan CironPierre M LabaugeCécile DulauDavid-Axel LaplaudJérôme de SèzeJean PelletierEric BergerChristine Lebrun-FrénayGiovanni CastelnovoGilles EdanGilles DeferPatrick VermerschBertrand BourreJean-Philippe CamdessanchéLaurent MagyA.-M. GuennocGuillaume MatheyThibault MoreauOlivier GoutO HeinzlefElisabeth MaillartSandra VukusicPierre Clavelou
• Organismes : CHU Clermont-Ferrand Neuro-Dol CHU Clermont-Ferrand CHU Clermont-Ferrand CHU Clermont-Ferrand Département de Neurologie [Toulouse] CHU Montpellier = Montpellier University Hospital Université de Montpellier Neurocentre Magendie : Physiopathologie de la Plasticité Neuronale CIC Bordeaux Centre Hospitalier Universitaire de Nantes = Nantes University Hospital CIC - Nantes Centre de Recherche en Transplantation et Immunologie CIC Strasbourg Service de Neurologie [Strasbourg] Assistance Publique - Hôpitaux de Marseille Service de Neurologie [CHRU Besançon] Hôpital Pasteur [Nice] Centre Hospitalier Universitaire de Nice Service de Neurologie [CHU Nimes] Centre d'Investigation Clinique [Rennes] Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Service de Neurologie [CHU Caen] Centre Hospitalier Régional Universitaire [CHU Lille] Lille Neurosciences & Cognition - U 1172 CHU Rouen Service de Neurologie [CHU de Saint-Étienne] Service de Neurochirurgie [CHU Limoges] Service de neuroradiologie [Tours] Maladies chroniques, santé perçue, et processus d'adaptation Service de neurologie [CHRU Nancy] Service de Neurologie générale, vasculaire et dégénérative (CHU de Dijon) Service de neurologie [Hôpital Fondation Adolphe de Rothschild] Service de Neurologie [CHU de Poissy] CHU Pitié-Salpêtrière [AP-HP] Hospices Civils de Lyon Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Université Claude Bernard Lyon 1 Neuro-Dol CHU Clermont-Ferrand
• Publié dans Neurotherapeutics le 01/11/2020

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Résumé : High-dose biotin (HDB) is a therapy used in non-active progressive multiple sclerosis (PMS). Several reports have suggested that HDB treatment may be associated with an increased risk of relapse. We aimed to determine whether HDB increases the risk of clinical relapse in PMS and describe the characteristics of the patients who experience it. We conducted a French, multicenter, retrospective study, comparing a group of PMS patients treated with HDB to a matched control group. Poisson regression was applied to model the specific statistical distribution of the annualized relapse rate (ARR). A propensity score (PS), based on the inverse probability of treatment weighting (IPTW), was used to adjust for indication bias and included the following variables: gender, primary PMS or not, age, EDSS, time since the last relapse, and co-prescription of a DMT. Two thousand six hundred twenty-eight patients treated with HDB and 654 controls were analyzed with a follow-up of 17 +/- 8 months. Among them, 148 validated relapses were observed in the group treated with biotin and 38 in the control group (p = 0.62). After adjustment based on the PS, the ARR was 0.044 +/- 0.23 for the biotin-treated group and 0.028 +/- 0.16 for the control group (p = 0.18). The more relapses there were before biotin, the higher the risk of relapse during treatment, independently from the use of HDB. While the number of relapses reported for patients with no previous inflammatory activity receiving biotin has gradually increased, the present retrospective study is adequately powered to exclude an elevated risk of relapse for patients with PMS treated with HDB.

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Fichiers liés : Mathais et al-2020-Relapses in Patients Treated with High-Dose Biotin.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Xavier DrayGuy HouistJean-Philippe Le MouelJean-Christophe SaurinGeoffroy VanbiervlietChloé LeandriGabriel RahmiClotilde DuburqueJulien KirchgesnerRomain LeenhardtFranck CholetLucille Quénéhervé
• Organismes : CHU Saint-Antoine [AP-HP] Institut Pierre Louis d'Epidémiologie et de Santé Publique Service d'Hépato Gastroenterologie [CHU Amiens-Picardie] Centre Hospitalier Universitaire de Nice Hôpital Européen Georges Pompidou [APHP] CHU Saint-Antoine [AP-HP] CHU Saint-Antoine [AP-HP]
• Publié dans Clinics and Research in Hepatology and Gastroenterology le 26/10/2020

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Fichiers liés : S2210740120303788.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Roel AaijCarlos Abellán BetetaThomas AckernleyBernardo AdevaMarco AdinolfiHossein AfsharniaChristine Angela AidalaSalvatore AiolaZiad AjaltouniSimon AkarJohannes AlbrechtFederico AlessioMichael AlexanderAlejandro Alfonso AlberoZakariya AlioucheGeorgy AlkhazovPaula Alvarez CartelleSandra AmatoYasmine AmhisLiupan AnLucio AnderliniAleksei AndreianovMirco AndreottiFlavio ArchilliAlexander ArtamonovMarina ArtusoKenenbek ArzymatovElie AslanidesMichele AtzeniBenjamin AudurierSebastian BachmannMarie BachmayerJohn BackSophie BakerPablo Baladron RodriguezVladislav BalaguraWander BaldiniJuan Baptista LeiteRoger BarlowSergey BarsukWilliam BarterMatteo BartoliniFedor BaryshnikovJan-Marc BaselsGiovanni BassiBaasansuren BatsukhAlexander BattigAurelio BayMaik BeckerFranco BedeschiIgnacio BediagaAndrew BeiterVladislav BelavinSamuel BelinViolaine BelleeKonstantin BelousIlia BelovIvan BelyaevGiovanni BencivenniEli Ben-HaimAlexander BerezhnoyRoland BernetDaniel BerninghoffHarris Conan BernsteinClaudia BertellaEmilie BertholetAlessandro BertolinChristopher BetancourtFederico BettiMarc-Olivier BettlerIaroslava BezshyikoSrishti BhasinJihyun BhomLingzhu BianMartin Stefan BiekerSimone BifaniPierre BilloirMatthew BirchFionn Caitlin Ros BishopAndrea BizzetiMikkel BjørnMichele Piero BlagoThomas BlakeFrederic BlancSteven BluskDana BobulskaJulian Alexander BoelhauveOscar Boente GarciaThomas BoettcherAlexey BoldyrevAlexander BondarNikolay BondarSilvia BorghiMaxim BorisyakMartino BorsatoJozef Tomasz BorsukSonia Amina BouchibaThemistocles BowcockAlexandre BoyerConcezio BozziMatthew John BradleySvende BraunAlexandre Brea RodriguezMichael BrodskiJolanta BrodzickaArnau Brossa GonzaloDavide BrunduAnnarita BuonauraChristopher BurrAlbert BurscheAnatoly ButkevichJordy Sebastiaan ButterJan BuytaertWiktor ByczynskiSandro CadedduHao CaiRoberto CalabreseLukas CaleficeLiliet Calero DiazStefano CaliRyan CalladineMarta CalviMiriam Calvo GomezPatricia Camargo MagalhaesAlessandro CamboniPierluigi CampanaDaniel Hugo Campora PerezAngel Fernando Campoverde QuezadaSimone CapelliLorenzo CapriottiAngelo CarboneGiovanni CarboniRoberta CardinaleAlessandro CardiniIna CarliPaolo CarnitiLeon David CarusKazuyoshi Carvalho AkibaAdrian Casais VidalGianluigi CasseMarco CattaneoGiovanni CavalleroSara CelaniJacopo CerasoliAbbie Jane ChadwickMatthew George ChapmanMatthew CharlesPh. CharpentierGeorgios ChatzikonstantinidisCarlos Alberto Chavez BarajasMaximilien ChefdevilleChen ChenShanzhen ChenAleksei ChernovStefan-Gabriel ChiticVeronika ChobanovaSerhii CholakMarcin ChrzaszczAlexsei ChubykinVladimir ChulikovPaolo CiambroneMaria Flavia CicalaXabier Cid VidalGregory CiezarekPeter ClarkeMarco ClemencicHarry CliffJoel ClosierJohn Leslie CobbledickVictor CocoJoao a B CoelhoJulien CoganEric CognerasLucian CojocariuPaula CollinsTommaso ColomboLiliana CongedoAndrea ContuNaomi CookeGeorge CoombsGloria CortiCayo Mar Costa SobralBenjamin CouturierDaniel Charles CraikJana CrkovskáMelissa Maria Cruz TorresRobert CurrieCesar Luiz da SilvaElena Dall'OccoJeremy DalsenoCarmelo d'AmbrosioAnna DanilinaPhilippe d'ArgentAdam DavisOscar de Aguiar FranciscoKristof de BruynStefano de CapuaMichel de CianJussara de MirandaLeandro de PaulaMarilisa de SerioDario de SimonePatrizia de SimoneJacco de VriesCameron Thomas DeanWilliam DeanDaniel DecampLuigi del BuonoBlaise DelaneyHans Peter DembinskiAdam DendekVadym DenysenkoDenis DerkachOlivier DeschampsFabrice DesseFrancesco DettoriBiplab DeyPasquale Di NezzaSergey DidenkoLorena Dieste MaronasHans DijkstraVasyl DobishukAmanda May DonohoeFrancesca DordeiAlberto dos ReisLauren DouglasAnatoliy DovbnyaAnthony Gavin DownesKarlis DreimanisMaciej Wojciech DudekLaurent DufourViacheslav DukPaolo DuranteJohn Matthew DurhamDeepanwita DuttaMichal DziewieckiAgnieszka DziurdaAlexey DzyubaSajan EasoUlrik EgedeVictor EgorychevSemen EidelmanStephan EisenhardtSurapat Ek-InLars EklundScott ElyAlexandru EneEliane EppleStephan EscherJonas Nathanael EschleSevda EsenTimothy EvansAntonio FalabellaJingzhou FanYanting FanBo FangNathanael FarleyStephen FarryDavide FazziniPetr FedinMauricio FéoPlacido Fernandez DeclaraAntonio Fernandez PrietoJose Maria Fernandez-Tenllado ArribasFabio FerrariLino Ferreira LopesFernando Ferreira RodriguesSilvia Ferreres SoleMartina FerrilloMassimiliano Ferro-LuzziSergey FilippovRosa Anna FiniMassimiliano FioriniMiroslaw FirlejKamil Leszek FischerConor FitzpatrickTomasz FiutowskiFrederic FleuretMarianna FontanaFlavio FontanelliRoger FortyVinicius Franco LimaManuel Franco SevillaMarkus FrankEdoardo FranzosoGiulia FrauChristoph FreiDavid Anthony FridayJinlin FuQuentin FuehringWolfgang FunkEmmy GabrielTatiana GaintsevaAbraham Gallas TorreiraDomenico GalliSilvia GambettaYuyue GanMiriam GandelmanPaolo GandiniYuanning GaoMichela GarauLuis Miguel Garcia MartinPaula Garcia MorenoJulián García PardiñasBeatriz Garcia PlanaFelipe Andres Garcia RosalesLluis GarridoClara GasparRobbert Erik GeertsemaDavid GerickLouis Lenard GerkenEvelina GersabeckMarco GersabeckTimothy GershonDawid GerstelPhilippe GhezValerie GibsonMatteo GiovannettiAlessandra GioventùPere Gironella GironellLavinia-Helena GiubegaCarmen GiuglianoKonstantin GizdovEvangelos Leonidas GkougkousisVladimir GligorovCarla GöbelElisabet GolobardesDmitry GolubkovAndrey GolutvinAlvaro GomesSergio Gomez FernandezFernanda Goncalves AbrantesMateusz GoncerzGuanghua GongPetr GorbounovIgor Vladimirovich GorelovClaudio GottiEkaterina GovorkovaJascha Peter GrabowskiRicardo Graciani DiazThomas GrammaticoLuis Alberto Granado CardosoEugeni GraugésElena GraveriniGiacomo GrazianiAlexandru GrecuLex Marinus GreevenPeter GriffithLucia GrilloSergey GromovBarak Raimond Gruberg CazonChenxi GuMarco GuarisePaul Andre GüntherEvgeny GushchinAndreas GuthYury GuzThierry GysThomas HadavizadehGuido HaefeliT. GysJakob HaimbergerSusan HainesTabitha Halewood-LeagasPhoebe Meredith HamiltonQundong HanXiaoxue HanThomas Henry HancockStephanie Hansmann-MenzemerNeville HarnewThomas HarrisonChristoph HasseMark HatchJibo HeMalte HeckerKevin HeijhoffKevin HeinickeArthur Marius HennequinKarol HennessyLouis HenryJohannes HeuelAdlène HicheurDonal HillMartha HiltonSophie Elizabeth HollittJiangqiao HuJifeng HuWenhua HuWenqian HuangXiaotao HuangWouter HulsbergenRoss John HunterMikhail HushchynDavid HutchcroftDaniel HyndsPhilipp IbisMarek IdzikDmitrii IlinPhilip IltenAlexander InglessiArtur IshteevKuzma IvshinRichard JacobssonSune JakobsenEddy JansBrij Kishor JashalAbolhassan JawaheryVukan JevticMarek JezabekE. JansMalcolm JohnA. JawaheryChristopher JonesThomas Peter JonesBeat JostNathan JurikSergii KandybeiYouen KangMatthias KaracsonMaksim KarpovNikita KazeevFloris KeizerMatthew KenzieTjeerd KetelBasem KhanjiAnastasiia KharisovaSergei KholodenkoKyung Eun KimThomas KirnVeronica Soelund KirsebomOuail KitouniSuzanne KlaverKonrad KlimaszewskiSerhii KoliievAlmagul KondybayevaAnatoly KonoplyannikovPawel KopciewiczRenata KopecnaPatrick KoppenburgMikhail KorolevIgor KostiukOleksander KotSofia KotriakhovaPolina KravchenkoLeonid KravchukRafal Dominik KrawczykMichal KrepsFelix Johannes KressSophie Katharina KretzschmarPavel KrokovnyWojciech KrupaWojciech KrzemienWojciech KucewiczMarcin KucharczykVasily KudryavtsevHilbrand Steffen KuindersmaGerd Joachim KundeTengiz KvaratskheliyaDaniel LacarrereGeorge LaffertyAdriano LaiAndrea LampisDavide LancieriniJohn Jake LaneRichard LaneGaia LanfranchiChristoph LangenbruchJan LangerOliver LantwinThomas LathamFederico LazzariRenaud Le GacSook Hyun LeeRegis LefèvreAlexander LeflatSergey LegotinOlivier LeroyTadeusz LesiakBlake LeveringtonHengne LiOlivier LeroyPeilian LiXuan LiYiming LiYutong LiZhuoming LiXixin LiangTai-Hua LinRolf LindnerVitalii LisovskyiRoman LitvinovGuoming LiuHuanhuan LiuShuaiyi LiuXuesong LiuAngelo LoiJulian Lomba CastroIain LongstaffJose LopesGuillermo LoustauGeorge Holger LovellYu LuDonatella LucchesiStanislav LuchukMiriam Lucio MartinezValeriia LukashenkoYiheng LuoAnna LupatoEleonora LuppiOliver LuptonAlberto LusianiXiao-Rui LyuLishuang MaSerena MaccoliniFrederic MachefertFlorin MaciucVladimir MackoPatrick MackowiakSamuel Maddrell-ManderOlga MadejczykLakshan Ram Madhan MohanOleg MaevArtem MaevskiyDmitrii MaisuzenkoMaciej Witold MajewskiJakub Jacek MalczewskiSneha MaldeBartosz MaleckiAlexander MalininTimofei MaltsevHanna MalyginaGiulia MancaGiampiero MancinelliRafel Manera EscaleroDaniele ManuzziDaniele MarangottoJan MaratasJean François MarchandUmberto MarconiSaverio MarianiCarla Marin BenitoMatthieu MarinangeliPietro MarinoJörg MarksPhillip John MarshallGiuseppe MartellottiLoris MartinazzoliMaurizio MartinelliDiego Martinez SantosFernando Martinez VidalAndré MassafferriMarcel MaterokRosen MatevAbhijit MathadZoltan MatheViacheslav MatiuninClara MatteuzziKara Renee MattioliAndrea MauriEmilie MauriceJuan MauricioMichal Kazimierz MazurekMichael MccannLucas McconnellTamaki Holly McgrathAndrew McnabRonan McnultyJames Vincent MeadBrian MeadowsCedric MeauxGerwin MeierNis MeinertDmytro MelnychukSimone MeloniMarcel MerkAndrea MerliLucas Meyer GarciaMikhail MikhasenkoDiego Alejandro MilanesEdward James MillardMarko MilovanovicMarie-Noelle MinardLuca MinzoniSara Elizabeth MitchellBiljana MitreskaDominik Stefan MitzelAntje MöddenRizwaan Adeeb MohammedRazvan Daniel MoiseTitus MombächerIgancio Alberto MonroyStephane MonteilMauro MorandinGianfranco MorelloMichael Joseph MorelloJakub MoronAdam Benjamin MorrisAndrew George MorrisRaymond MountainHongjie MuFranz MuheimMaitreyee MukherjeeMick MulderDominik MüllerKatharina MüllerColm Harold MurphyDonal MurrayPiera MuzzettoParas NaikTatsuya NakadaRaja NandakumarTara NanutIrina NastevaMatthew NeedhamIlaria NeriNicola NeriSebastian NeubertNiko NeufeldRyan NewcombeThi Dung NguyenChung Nguyen-MauElisabeth Maria NielSimon NieswandNikolay NikitinNiklas Stefan NolteCynthia NunezAgnieszka Oblakowska-MuchaVladimir ObraztsovDaniel Patrick O'HanlonRudolf OldemanMario Edgardo OlivaresGerco OnderwaterAnna OssowskaJuan Martin Otalora GoicocheaTatiana OvsiannikovaPatrick OwenMaria Aranzazu OyangurenBhagyashree PagarePreema Rennee PaisTommaso PajeroAntimo PalanoMatteo PalutanYue PanGennady PanshinAntonios PapanestisMarco PappagalloLuciano PappalardoCheryl PappenheimerWilliam ParkerChristopher ParkesChristopher John ParkinsonBarbara PassalacquaGiovanni PassalevaAlessandra PastoreMitesh PatelClaudia PatrignaniChristopher James PawleyAlex PearceAntonio PellegrinoMonica Pepe AltarelliStefano PerazziniDmitrii PereimaPascal PerretKonstantinos PetridisAlessandro PetroliniAleksandr PetrovStefano PetrucciMarco PetruzzoThi Thuy Hang PhamAnton PhilippovLorenzo PicaMauro PicciniBoleslaw PietrzykGuillaume PietrzykMartina PiliDavide PinciJacopo PinzinoFlavio PisaniAlessio PiucciResmi PkVlad-Mihai PlacintaJonathan PlewsMaximo Plo CasasusFrancesco PolciMarco Poli LenerMariia PoliakovaAnton PoluektovNatalia PolukhinaIvan PolyakovErica PolycarpoGabriela Johanna PomerySebastien PonceGabriela Johanna PomerySergei PopovStanislav PoslavskiiKodassery PrasanthLaura PrombergerClaire ProuveValery PugatchAlbert Puig NavarroHannah Louise PullenGiovanni PunziWenbin QianJia-Jia QinRenato QuaglianiBoris QuintanaNaomi Veronika RaabRaul Iraq Rabadan TrejoBartlomiej RachwalJonas RademackerMatteo RamaMiguel Ramos PernasMurilo RangelFedor RatnikovGerhard RavenMéril ReboudFederico RediFlorian ReissClara Remon AlepuzZan RenVictor RenaudinRoberto RibattiStefania RicciardiKurt RinnertPatrick RobbeArnaud RobertGary RobertsonAna Barbara RodriguesEduardo RodriguesJairo Alexis Rodriguez LopezAlexandra Paige RollingsPhilipp RoloffVladimir RomanovskiyMarcos Romero LamasAntonio Romero VidalJordan Daniel RothMarcello RotondoMatthew Scott RudolphThomas RufJoan Ruiz VidalArtem RyzhikovJakub RyzkaJuan Jose Saborido SilvaNaylya SagidovaNiladribihari SahooBiagio SaittaDavid Sanchez GonzaloCristina Sanchez GrasRoberta SantacesariaCibran Santamarina RiosMarco SantimariaEmanuele SantovettiDanila SaraninGediminas SarpisMinaugas SarpisAlessio SartiCelestina SatrianoAlessia SattaMiroslav SaurDarya SavrinaHalime SazakLuke George Scantlebury SmeadStefan SchaelMargarete SchellenbergManuel SchillerHeinrich SchindlerMichael SchmellingTimon SchmelzerBurkhard SchmidtOlivier SchneiderAndreas SchopperMaxime SchubigerSebastian SchulteMarie Helene SchuneRainer SchwemmerBarbara SciasciaAdalberto SciubbaSara SellamAlexander SemennikovMara Senghi SoaresAntonino SergiNicola SerraLorenzo SestiniAlex SeuthePaul SeyfertDesmond Mzamo ShangaseMikhail ShapkinIvan ShchemerovLesya ShchutskaTara ShearsLev ShekhtmanZhihong ShenVladimir ShevchenkoEdward Brendan ShieldsEvgenii ShmaninJoseph David ShupperdBenedetto Gianluca SiddiRafael Silva CoutinhoGabriele SimiSaverio SimoneIgor SkibaNicola SkidmoreTomasz SkwarnickiMark SlaterJennifer Clare SmallwoodJohn Gordon SmeatonAnastasia SmetkinaEluned SmithMark SmithAleksandra SnochMarcelo SoaresLais Soares LavraMichael SokoloffPaul SolerAleksandr SolovevIvan SolovyevFelipe Luan Souza de AlmeidaBruno Souza de PaulaBernhard SpaanElisabetta Spadaro NorellaPatrick SpradlinFederico StagniMarian StahlSascha StahlPavol StefkoOlaf SteinkampSimon StemmleOleg StenyakinHolger StevensSheldon StoneMaria Elena StramagliaMihai StraticiucDaria StrekalinaSergey StrokovFidan SuljikJiayin SunLiang SunYipeng SunPeter SvihraPaul Nathaniel SwallowKrzysztof SwientekAdam SzabelskiTomasz SzumlakMaciej Pawel SzymanskiShantam TanejaTobias TekampeFrederic TeubertEric ThomasKayleigh Anne ThomsonMatthew James TilleyVincent TisserandStephane t'JampensMark TobinSiim TolkLuca TomassettiDiego Torres Machadoda Yu TouMurdo TraillMinh Tâm TranEkaterina TrifonovaCarina TripplGiulia TuciAlison TullyNiels TuningArtur UklejaDaniel Joachim UnverzagtEduard UrsovAndrii UsachovAndrey UstyuzhaninUlrich UwerAlexander VagnerVincenzo VagnoniAndrea ValassiGiovanni ValentiNuria Valls CanudasMartinus van BeuzekomMaarten van DijkHubert van HeckeEric van HerwijnenCharlotte Barbara van HulseMaarten van VeghelRicardo Vazquez GomezPablo Vazquez RegueiroCarlos Vázquez SierraStefania VecchiJaap VelthuisMichele VeltriAravindhan VenkateswaranMichele VeronesiMika VesterinenDaniel VieiraMaria Vieites DiazHarald ViemannXavier Vilasis-CardonaEva Vilella FiguerasPascal VincentGiacomo VitaliAchim VollhardtDorothea Vom BruchAlexey VorobyevVitaly VorobyevNikolai VoropaevRoland WaldiJohn WalshChishuai WangJianqiao WangJike WangJialu WangJianchun WangMengzhen WangRui WangE. Vilella FiguerasZhenzi WangHeather Mckenzie WarkNigel WatsonSteffen Georg WeberDavid WebsdaleConstantin WeisserBenedict Donald C WesthenryDylan Jaide WhiteMark WhiteheadDirk WiednerGuy WilkinsonMichael WilkinsonIfan WilliamsMike WilliamsMark Richard James WilliamsFergus WilsonWojciech WislickiMariusz WitekLukas WitolaGuy WormserStephen WottonHangyi WuKenneth WyllieZhiyu XiangDong XiaoYuehong XieAo XuJingyi XuLi XuMenglin XuQingnian XuZhihao XuZehua XuDi YangYouhua YangZhenwei YangZishuo YangYuezhe YaoLauren Emma YeomansHang YinJiesheng YuXuhao YuanOleg YushchenkoEttore ZaffaroniKristian Alexander ZarebskiMikhail ZavertyaevMilosz ZdybalOleksandr ZenaievMing ZengDongliang ZhangLiming ZhangShunan ZhangYanxi ZhangYu ZhangAlexey ZhelezovYangheng ZhengXiaokang ZhouYixiong ZhouXianglei ZhuValery ZhukovJennifer Brigitta ZonneveldStefano ZucchelliDavide ZulianiGianluca Zunica
• Organismes : Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire Leprince-Ringuet Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie
• Publié dans Journal of High Energy Physics le 23/10/2020

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Résumé : The time-dependent CP asymmetries of B$^{0}$→ π$^{+}$π$^{−}$ and $ {B}_s^0 $→ K$^{+}$K$^{−}$ decays are measured using a data sample of pp collisions corresponding to an integrated luminosity of 1.9 fb$^{−1}$, collected with the LHCb detector at a centre-of-mass energy of 13 TeV. The results are$ {\displaystyle \begin{array}{c}{C}_{\pi \pi}=-0.311\pm 0.045\pm 0.015,\\ {}{S}_{\pi \pi}=-0.706\pm 0.042\pm 0.013,\\ {}{C}_{KK}=0.123\pm 0.034\pm 0.015,\\ {}{S}_{KK}=0.164\pm 0.034\pm 0.014,\\ {}{\mathcal{A}}_{KK}^{\Delta \varGamma }=-0.83\pm 0.05\pm 0.09,\end{array}} $where the first uncertainties are statistical and the second systematic. The same data sample is used to measure the time-integrated CP asymmetries of B$^{0}$→ K + π$^{−}$ and $ {B}_s^0 _{→}$K$^{−}$π$^{+}$ decays and the results are$ {\displaystyle \begin{array}{c}{A}_{CP}^{B^0}=-0.0824\pm 0.0033\pm 0.0033,\\ {}{A}_{CP}^{B_s^0}=0.236\pm 0.013\pm 0.011.\end{array}} $All results are consistent with earlier measurements. A combination of LHCb measurements provides the first observation of time-dependent CP violation in $ {B}_s^0 $ decays.[graphic not available: see fulltext]

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Matteo GhidelliAndrey OrekhovAndrea Li BassiGiancarlo TerraneoP. DjemiaGrégory AbadiasMagnus NordArmand BéchéNicolas GauquelinJohan VerbeeckJean-Pierre RaskinDominique SchryversThomas PardoenHosni Idrissi
• Organismes : Laboratoire des Sciences des Procédés et des Matériaux Universiteit Antwerpen = University of Antwerp Politecnico di Milano [Milan] Politecnico di Milano [Milan] Laboratoire des Sciences des Procédés et des Matériaux Physique et Propriétés des Nanostructures [Institut Pprime] Universiteit Antwerpen = University of Antwerp Universiteit Antwerpen = University of Antwerp Universiteit Antwerpen = University of Antwerp Universiteit Antwerpen = University of Antwerp Université Catholique de Louvain = Catholic University of Louvain Universiteit Antwerpen = University of Antwerp Université Catholique de Louvain = Catholic University of Louvain Université Catholique de Louvain = Catholic University of Louvain
• Publié dans Acta Materialia le 25/10/2020

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Résumé : A novel class of nanostructured Zr50Cu50 (%at.) metallic glass films with superior and tunable mechanical properties is produced by pulsed laser deposition. The process can be controlled to synthetize a wide range of film microstructures including dense fully amorphous, amorphous embedded with nanocrystals and amorphous nano-granular. A unique dense self-assembled nano-laminated atomic arrangement characterized by alternating Cu-rich and Zr/O-rich nanolayers with different local chemical enrichment and amorphous or amorphous-crystalline composite nanostructure has been discovered, while significant in-plane clustering is reported for films synthetized at high deposition pressures. This unique nanoarchitecture is at the basis of superior mechanical properties including large hardness and elastic modulus up to 10 and 140 GPa, respectively and outstanding total elongation to failure (>9%), leading to excellent strength/ductility balance, which can be tuned by playing with the film architecture. These results pave the way to the synthesis of novel class of engineered nanostructured metallic glass films with high structural performances attractive for a number of applications in microelectronics and coating industry.

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Fichiers liés : Ghidelli et al_ Manuscript_DEF_II.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Roel AaijCarlos Abellán BetetaThomas AckernleyBernardo AdevaMarco AdinolfiHossein AfsharniaChristine Angela AidalaSalvatore AiolaZiad AjaltouniSimon AkarJohannes AlbrechtFederico AlessioMichael AlexanderAlejandro Alfonso AlberoZakariya AlioucheGeorgy AlkhazovPaula Alvarez CartelleSandra AmatoYasmine AmhisLiupan AnLucio AnderliniAleksei AndreianovMirco AndreottiFlavio ArchilliAlexander ArtamonovMarina ArtusoKenenbek ArzymatovElie AslanidesMichele AtzeniBenjamin AudurierSebastian BachmannMarie BachmayerJohn BackSophie BakerPablo Baladron RodriguezVladislav BalaguraWander BaldiniJuan Baptista LeiteRoger BarlowSergey BarsukWilliam BarterMatteo BartoliniFedor BaryshnikovJan-Marc BaselsGiovanni BassiBaasansuren BatsukhAlexander BattigAurelio BayMaik BeckerFranco BedeschiIgnacio BediagaAndrew BeiterVladislav BelavinSamuel BelinViolaine BelleeKonstantin BelousIlia BelovIvan BelyaevGiovanni BencivenniEli Ben-HaimAlexander BerezhnoyRoland BernetDaniel BerninghoffHarris Conan BernsteinClaudia BertellaEmilie BertholetAlessandro BertolinChristopher BetancourtFederico BettiIaroslava BezshyikoSrishti BhasinJihyun BhomLingzhu BianMartin Stefan BiekerSimone BifaniPierre BilloirMatthew BirchFionn Caitlin Ros BishopAndrea BizzetiMikkel BjørnMichele Piero BlagoThomas BlakeFrederic BlancSteven BluskDana BobulskaJulian Alexander BoelhauveOscar Boente GarciaThomas BoettcherAlexey BoldyrevAlexander BondarNikolay BondarSilvia BorghiMaxim BorisyakMartino BorsatoJozef Tomasz BorsukSonia Amina BouchibaThemistocles BowcockAlexandre BoyerConcezio BozziMatthew John BradleySvende BraunAlexandre Brea RodriguezMichael BrodskiJolanta BrodzickaArnau Brossa GonzaloDavide BrunduAnnarita BuonauraChristopher BurrAlbert BurscheAnatoly ButkevichJordy Sebastiaan ButterJan BuytaertWiktor ByczynskiSandro CadedduHao CaiRoberto CalabreseLukas CaleficeLiliet Calero DiazStefano CaliRyan CalladineMarta CalviMiriam Calvo GomezPatricia Camargo MagalhaesAlessandro CamboniPierluigi CampanaAngel Fernando Campoverde QuezadaSimone CapelliLorenzo CapriottiAngelo CarboneGiovanni CarboniRoberta CardinaleAlessandro CardiniIna CarliPaolo CarnitiLeon David CarusKazuyoshi Carvalho AkibaAdrian Casais VidalGianluigi CasseMarco CattaneoGiovanni CavalleroSara CelaniJacopo CerasoliAbbie Jane ChadwickMatthew George ChapmanMatthew CharlesPh. CharpentierGeorgios ChatzikonstantinidisCarlos Alberto Chavez BarajasMaximilien ChefdevilleChen ChenShanzhen ChenAleksei ChernovStefan-Gabriel ChiticVeronika ChobanovaSerhii CholakMarcin ChrzaszczAlexsei ChubykinVladimir ChulikovPaolo CiambroneMaria Flavia CicalaXabier Cid VidalGregory CiezarekPeter ClarkeMarco ClemencicHarry CliffJoel ClosierJohn Leslie CobbledickVictor CocoJoao a B CoelhoJulien CoganEric CognerasLucian CojocariuPaula CollinsTommaso ColomboLiliana CongedoAndrea ContuNaomi CookeGeorge CoombsGloria CortiCayo Mar Costa SobralBenjamin CouturierDaniel Charles CraikJana CrkovskáMelissa Maria Cruz TorresRobert CurrieCesar Luiz da SilvaElena Dall'OccoJeremy DalsenoCarmelo d'AmbrosioAnna DanilinaPhilippe d'ArgentAdam DavisOscar de Aguiar FranciscoKristof de BruynStefano de CapuaMichel de CianJussara de MirandaLeandro de PaulaMarilisa de SerioDario de SimonePatrizia de SimoneJacco de VriesCameron Thomas DeanWilliam DeanDaniel DecampLuigi del BuonoBlaise DelaneyHans Peter DembinskiAdam DendekVadym DenysenkoDenis DerkachOlivier DeschampsFabrice DesseFrancesco DettoriBiplab DeyPasquale Di NezzaSergey DidenkoLorena Dieste MaronasHans DijkstraVasyl DobishukAmanda May DonohoeFrancesca DordeiAlberto dos ReisLauren DouglasAnatoliy DovbnyaAnthony Gavin DownesKarlis DreimanisMaciej Wojciech DudekLaurent DufourViacheslav DukPaolo DuranteJohn Matthew DurhamDeepanwita DuttaMichal DziewieckiAgnieszka DziurdaAlexey DzyubaSajan EasoUlrik EgedeVictor EgorychevSemen EidelmanStephan EisenhardtSurapat Ek-InLars EklundScott ElyAlexandru EneEliane EppleStephan EscherJonas Nathanael EschleSevda EsenTimothy EvansAntonio FalabellaJingzhou FanYanting FanBo FangNathanael FarleyStephen FarryDavide FazziniPetr FedinMauricio FéoPlacido Fernandez DeclaraAntonio Fernandez PrietoJose Maria Fernandez-Tenllado ArribasFabio FerrariLino Ferreira LopesFernando Ferreira RodriguesSilvia Ferreres SoleMartina FerrilloMassimiliano Ferro-LuzziSergey FilippovRosa Anna FiniMassimiliano FioriniMiroslaw FirlejKamil Leszek FischerConor FitzpatrickTomasz FiutowskiFrederic FleuretMarianna FontanaFlavio FontanelliRoger FortyVinicius Franco LimaManuel Franco SevillaMarkus FrankEdoardo FranzosoGiulia FrauChristoph FreiDavid Anthony FridayJinlin FuQuentin FuehringWolfgang FunkEmmy GabrielTatiana GaintsevaAbraham Gallas TorreiraDomenico GalliSilvia GambettaYuyue GanMiriam GandelmanPaolo GandiniYuanning GaoMichela GarauLuis Miguel Garcia MartinPaula Garcia MorenoJulián García PardiñasBeatriz Garcia PlanaFelipe Andres Garcia RosalesLluis GarridoClara GasparRobbert Erik GeertsemaDavid GerickLouis Lenard GerkenEvelina GersabeckMarco GersabeckTimothy GershonDawid GerstelPhilippe GhezValerie GibsonMatteo GiovannettiAlessandra GioventùPere Gironella GironellLavinia-Helena GiubegaCarmen GiuglianoKonstantin GizdovEvangelos Leonidas GkougkousisVladimir GligorovCarla GöbelElisabet GolobardesDmitry GolubkovAndrey GolutvinAlvaro GomesSergio Gomez FernandezFernanda Goncalves AbrantesMateusz GoncerzGuanghua GongPetr GorbounovIgor Vladimirovich GorelovClaudio GottiEkaterina GovorkovaJascha Peter GrabowskiRicardo Graciani DiazThomas GrammaticoLuis Alberto Granado CardosoEugeni GraugésElena GraveriniGiacomo GrazianiAlexandru GrecuLex Marinus GreevenPeter GriffithLucia GrilloSergey GromovBarak Raimond Gruberg CazonChenxi GuMarco GuarisePaul Andre GüntherEvgeny GushchinAndreas GuthYury GuzThierry GysThomas HadavizadehGuido HaefeliT. GysJakob HaimbergerTabitha Halewood-LeagasPhoebe Meredith HamiltonQundong HanXiaoxue HanThomas Henry HancockStephanie Hansmann-MenzemerNeville HarnewThomas HarrisonChristoph HasseMark HatchJibo HeMalte HeckerKevin HeijhoffKevin HeinickeArthur Marius HennequinKarol HennessyLouis HenryJohannes HeuelAdlène HicheurDonal HillMartha HiltonSophie Elizabeth HollittJiangqiao HuJifeng HuWenhua HuWenqian HuangXiaotao HuangWouter HulsbergenRoss John HunterMikhail HushchynDavid HutchcroftDaniel HyndsPhilipp IbisMarek IdzikDmitrii IlinPhilip IltenAlexander InglessiArtur IshteevKuzma IvshinRichard JacobssonSune JakobsenEddy JansBrij Kishor JashalAbolhassan JawaheryVukan JevticMarek JezabekE. JansMalcolm JohnA. 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ShevchenkoEdward Brendan ShieldsEvgenii ShmaninJoseph David ShupperdBenedetto Gianluca SiddiRafael Silva CoutinhoGabriele SimiSaverio SimoneIgor SkibaNicola SkidmoreTomasz SkwarnickiMark SlaterJennifer Clare SmallwoodJohn Gordon SmeatonAnastasia SmetkinaEluned SmithMark SmithAleksandra SnochMarcelo SoaresLais Soares LavraMichael SokoloffPaul SolerAleksandr SolovevIvan SolovyevFelipe Luan Souza de AlmeidaBruno Souza de PaulaBernhard SpaanElisabetta Spadaro NorellaPatrick SpradlinFederico StagniMarian StahlSascha StahlPavol StefkoOlaf SteinkampSimon StemmleOleg StenyakinHolger StevensSheldon StoneMaria Elena StramagliaMihai StraticiucDaria StrekalinaSergey StrokovFidan SuljikJiayin SunLiang SunYipeng SunPeter SvihraPaul Nathaniel SwallowKrzysztof SwientekAdam SzabelskiTomasz SzumlakMaciej Pawel SzymanskiShantam TanejaFrederic TeubertEric ThomasKayleigh Anne ThomsonMatthew James TilleyVincent TisserandStephane t'JampensMark TobinSiim TolkLuca TomassettiDiego Torres Machadoda Yu TouMurdo TraillMinh Tâm TranEkaterina TrifonovaCarina TripplGiulia TuciAlison TullyNiels TuningArtur UklejaDaniel Joachim UnverzagtEduard UrsovAndrii UsachovAndrey UstyuzhaninUlrich UwerAlexander VagnerVincenzo VagnoniAndrea ValassiGiovanni ValentiNuria Valls CanudasMartinus van BeuzekomMaarten van DijkEric van HerwijnenCharlotte Barbara van HulseMaarten van VeghelRicardo Vazquez GomezPablo Vazquez RegueiroCarlos Vázquez SierraStefania VecchiJaap VelthuisMichele VeltriAravindhan VenkateswaranMichele VeronesiMika VesterinenDaniel VieiraMaria Vieites DiazHarald ViemannXavier Vilasis-CardonaEva Vilella FiguerasPascal VincentGiacomo VitaliAchim VollhardtDorothea Vom BruchAlexey VorobyevVitaly VorobyevNikolai VoropaevRoland WaldiJohn WalshChishuai WangJianqiao WangJike WangJialu WangJianchun WangMengzhen WangRui WangE. Vilella FiguerasZhenzi WangHeather Mckenzie WarkNigel WatsonSteffen Georg WeberDavid WebsdaleConstantin WeisserBenedict Donald C WesthenryDylan Jaide WhiteMark WhiteheadDirk WiednerGuy WilkinsonMichael WilkinsonIfan WilliamsMike WilliamsMark Richard James WilliamsFergus WilsonWojciech WislickiMariusz WitekLukas WitolaGuy WormserStephen WottonHangyi WuKenneth WyllieZhiyu XiangDong XiaoYuehong XieAo XuJingyi XuLi XuMenglin XuQingnian XuZhihao XuZehua XuDi YangYouhua YangZhenwei YangZishuo YangYuezhe YaoLauren Emma YeomansHang YinJiesheng YuXuhao YuanOleg YushchenkoEttore ZaffaroniKristian Alexander ZarebskiMikhail ZavertyaevMilosz ZdybalOleksandr ZenaievMing ZengDongliang ZhangLiming ZhangShunan ZhangYanxi ZhangYu ZhangAlexey ZhelezovYangheng ZhengXiaokang ZhouYixiong ZhouXianglei ZhuValery ZhukovJennifer Brigitta ZonneveldStefano ZucchelliDavide ZulianiGianluca Zunica
• Organismes : Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire Leprince-Ringuet Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie
• Publié dans Journal of High Energy Physics le 23/10/2020

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Résumé : Measurements of CP observables in B$^{±}$ → D$^{(*)}$K$^{±}$ and B$^{±}$ → D$^{(*)}$π$^{±}$ decays are presented, where D$^{(∗)}$ indicates a neutral D or D$^{∗}$ meson that is an admixture of meson and anti-meson states. Decays of the D$^{(∗)}$ meson to the Dπ$^{0}$ and Dγ final states are partially reconstructed without inclusion of the neutral pion or photon. Decays of the D meson are reconstructed in the K$^{±}$π$^{∓}$, K$^{+}$K$^{−}$, and π$^{+}$π$^{−}$ final states. The analysis uses a sample of charged B mesons produced in proton-proton collisions and collected with the LHCb experiment, corresponding to integrated luminosities of 2.0, 1.0, and 5.7 fb$^{−1}$ taken at centre-of-mass energies of 7, 8, and 13 TeV, respectively. The measurements of partially reconstructed B$^{±}$ → D$^{(*)}$K$^{±}$ and B$^{±}$ → D$^{(∗)}$π$^{±}$ with D → K$^{∓}$π$^{±}$ decays are the first of their kind, and a first observation of the B$^{±}$ → $ {\left(D{\pi}^0\right)}_{D^{\ast }}{\pi}^{\pm } $ decay is made with a significance of 6.1 standard deviations. All CP observables are measured with world-best precision, and in combination with other LHCb results will provide strong constraints on the CKM angle γ.[graphic not available: see fulltext]

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Source

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Roel AaijCarlos Abellán BetetaThomas AckernleyBernardo AdevaMarco AdinolfiHossein AfsharniaChristine Angela AidalaSalvatore AiolaZiad AjaltouniSimon AkarJohannes AlbrechtFederico AlessioMichael AlexanderAlejandro Alfonso AlberoZakariya AlioucheGeorgy AlkhazovPaula Alvarez CartelleSandra AmatoYasmine AmhisLiupan AnLucio AnderliniAleksei AndreianovMirco AndreottiFlavio ArchilliAlexander ArtamonovMarina ArtusoKenenbek ArzymatovElie AslanidesMichele AtzeniBenjamin AudurierSebastian BachmannMarie BachmayerJohn BackSophie BakerPablo Baladron RodriguezVladislav BalaguraWander BaldiniJuan Baptista LeiteRoger BarlowSergey BarsukWilliam BarterMatteo BartoliniFedor BaryshnikovJan-Marc BaselsGiovanni BassiBaasansuren BatsukhAlexander BattigAurelio BayMaik BeckerFranco BedeschiIgnacio BediagaAndrew BeiterVladislav BelavinSamuel BelinViolaine BelleeKonstantin BelousIlia BelovIvan BelyaevGiovanni BencivenniEli Ben-HaimAlexander BerezhnoyRoland BernetDaniel BerninghoffHarris Conan BernsteinClaudia BertellaAlessandro BertolinChristopher BetancourtFederico BettiIaroslava BezshyikoSrishti BhasinJihyun BhomLingzhu BianMartin Stefan BiekerSimone BifaniPierre BilloirMatthew BirchFionn Caitlin Ros BishopAlexander BitadzeAndrea BizzetiMikkel BjørnMichele Piero BlagoThomas BlakeFrederic BlancSteven BluskDana BobulskaJulian Alexander BoelhauveOscar Boente GarciaThomas BoettcherAlexey BoldyrevAlexander BondarNikolay BondarSilvia BorghiMaxim BorisyakMartino BorsatoJozef Tomasz BorsukSonia Amina BouchibaThemistocles BowcockAlexandre BoyerConcezio BozziMatthew John BradleySvende BraunAlexandre Brea RodriguezMichael BrodskiJolanta BrodzickaArnau Brossa GonzaloDavide BrunduAnnarita BuonauraChristopher BurrAlbert BurscheAnatoly ButkevichJordy Sebastiaan ButterJan BuytaertWiktor ByczynskiSandro CadedduHao CaiRoberto CalabreseLukas CaleficeLiliet Calero DiazStefano CaliRyan CalladineMarta CalviMiriam Calvo GomezPatricia Camargo MagalhaesAlessandro CamboniPierluigi CampanaAngel Fernando Campoverde QuezadaSimone CapelliLorenzo CapriottiAngelo CarboneGiovanni CarboniRoberta CardinaleAlessandro CardiniIna CarliPaolo CarnitiLeon David CarusKazuyoshi Carvalho AkibaAdrian Casais VidalGianluigi CasseMarco CattaneoGiovanni CavalleroSara CelaniJacopo CerasoliAbbie Jane ChadwickMatthew George ChapmanMatthew CharlesPh. 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JawaheryChristopher JonesThomas Peter JonesBeat JostNathan JurikSergii KandybeiYouen KangMatthias KaracsonMaksim KarpovNikita KazeevFloris KeizerMatthew KenzieTjeerd KetelBasem KhanjiAnastasiia KharisovaSergei KholodenkoKyung Eun KimThomas KirnVeronica Soelund KirsebomOuail KitouniSuzanne KlaverKonrad KlimaszewskiSerhii KoliievAlmagul KondybayevaAnatoly KonoplyannikovPawel KopciewiczRenata KopecnaPatrick KoppenburgMikhail KorolevIgor KostiukOleksander KotSofia KotriakhovaPolina KravchenkoLeonid KravchukRafal Dominik KrawczykMichal KrepsFelix Johannes KressSophie Katharina KretzschmarPavel KrokovnyWojciech KrupaWojciech KrzemienWojciech KucewiczMarcin KucharczykVasily KudryavtsevHilbrand Steffen KuindersmaGerd Joachim KundeTengiz KvaratskheliyaDaniel LacarrereGeorge LaffertyAdriano LaiAndrea LampisDavide LancieriniJohn Jake LaneRichard LaneGaia LanfranchiChristoph LangenbruchJan LangerOliver LantwinThomas LathamFederico LazzariRenaud Le GacSook Hyun LeeRegis LefèvreAlexander LeflatSergey LegotinOlivier LeroyTadeusz LesiakBlake LeveringtonHengne LiOlivier LeroyPeilian LiYiming LiYutong LiZhuoming LiXixin LiangTai-Hua LinRolf LindnerVitalii LisovskyiRoman LitvinovGuoming LiuHuanhuan LiuShuaiyi LiuXuesong LiuAngelo LoiJulian Lomba CastroIain LongstaffJose LopesGeorge Holger LovellYu LuDonatella LucchesiStanislav LuchukMiriam Lucio MartinezValeriia LukashenkoYiheng LuoAnna LupatoEleonora LuppiOliver LuptonAlberto LusianiXiao-Rui LyuLishuang MaSerena MaccoliniFrederic MachefertFlorin MaciucVladimir MackoPatrick MackowiakSamuel Maddrell-ManderOlga MadejczykLakshan Ram Madhan MohanOleg MaevArtem MaevskiyDmitrii MaisuzenkoMaciej Witold MajewskiJakub Jacek MalczewskiSneha MaldeBartosz MaleckiAlexander MalininTimofei MaltsevHanna MalyginaGiulia MancaGiampiero MancinelliRafel Manera EscaleroDaniele ManuzziDaniele MarangottoJan MaratasJean François MarchandUmberto MarconiSaverio MarianiCarla Marin BenitoMatthieu MarinangeliPietro MarinoJörg MarksPhillip John MarshallGiuseppe MartellottiLoris MartinazzoliMaurizio MartinelliDiego Martinez SantosFernando Martinez VidalAndré MassafferriMarcel MaterokRosen MatevAbhijit MathadZoltan MatheViacheslav MatiuninClara MatteuzziKara Renee MattioliAndrea MauriEmilie MauriceJuan MauricioMichal Kazimierz MazurekMichael MccannLucas McconnellTamaki Holly McgrathAndrew McnabRonan McnultyJames Vincent MeadBrian MeadowsCedric MeauxGerwin MeierNis MeinertDmytro MelnychukSimone MeloniMarcel MerkAndrea MerliLucas Meyer GarciaMikhail MikhasenkoDiego Alejandro MilanesEdward James MillardMarko MilovanovicMarie-Noelle MinardLuca MinzoniSara Elizabeth MitchellBiljana MitreskaDominik Stefan MitzelAntje MöddenRizwaan Adeeb MohammedRazvan Daniel MoiseTitus MombächerIgancio Alberto MonroyStephane MonteilMauro MorandinGianfranco MorelloMichael Joseph MorelloJakub MoronAdam Benjamin MorrisAndrew George MorrisRaymond MountainHongjie MuFranz MuheimMaitreyee MukherjeeMick MulderDominik MüllerKatharina MüllerColm Harold MurphyDonal MurrayPiera MuzzettoParas NaikTatsuya NakadaRaja NandakumarTara NanutIrina NastevaMatthew NeedhamIlaria NeriNicola NeriSebastian NeubertNiko NeufeldRyan NewcombeThi Dung NguyenChung Nguyen-MauElisabeth Maria NielSimon NieswandNikolay NikitinNiklas Stefan NolteCynthia NunezAgnieszka Oblakowska-MuchaVladimir ObraztsovDaniel Patrick O'HanlonRudolf OldemanMario Edgardo OlivaresC.J.G. 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SolerAleksandr SolovevIvan SolovyevFelipe Luan Souza de AlmeidaBruno Souza de PaulaBernhard SpaanElisabetta Spadaro NorellaPatrick SpradlinFederico StagniMarian StahlSascha StahlPavol StefkoOlaf SteinkampSimon StemmleOleg StenyakinHolger StevensSheldon StoneMaria Elena StramagliaMihai StraticiucDaria StrekalinaFidan SuljikJiayin SunLiang SunYipeng SunPeter SvihraPaul Nathaniel SwallowKrzysztof SwientekAdam SzabelskiTomasz SzumlakMaciej Pawel SzymanskiShantam TanejaFrederic TeubertEric ThomasKayleigh Anne ThomsonMatthew James TilleyVincent TisserandStephane t'JampensMark TobinSiim TolkLuca TomassettiDiego Torres Machadoda Yu TouMurdo TraillMinh Tâm TranEkaterina TrifonovaCarina TripplGiulia TuciAlison TullyNiels TuningArtur UklejaDaniel Joachim UnverzagtEduard UrsovAndrii UsachovAndrey UstyuzhaninUlrich UwerAlexander VagnerVincenzo VagnoniAndrea ValassiGiovanni ValentiNuria Valls CanudasMartinus van BeuzekomMaarten van DijkEric van HerwijnenCharlotte Barbara van HulseMaarten van VeghelRicardo Vazquez GomezPablo Vazquez RegueiroCarlos Vázquez SierraStefania VecchiJaap VelthuisMichele VeltriAravindhan VenkateswaranMichele VeronesiMika VesterinenDaniel VieiraMaria Vieites DiazHarald ViemannXavier Vilasis-CardonaEva Vilella FiguerasPascal VincentGiacomo VitaliAchim VollhardtDorothea Vom BruchAlexey VorobyevVitaly VorobyevNikolai VoropaevRoland WaldiJohn WalshChishuai WangJialu WangJianchun WangJianqiao WangJike WangMengzhen WangRui WangE. Vilella FiguerasZhenzi WangHeather Mckenzie WarkNigel WatsonSteffen Georg WeberDavid WebsdaleConstantin WeisserBenedict Donald C WesthenryDylan Jaide WhiteMark WhiteheadDirk WiednerGuy WilkinsonMichael WilkinsonIfan WilliamsMike WilliamsMark Richard James WilliamsFergus WilsonWojciech WislickiMariusz WitekLukas WitolaGuy WormserStephen WottonHangyi WuKenneth WyllieZhiyu XiangDong XiaoYuehong XieAo XuJingyi XuLi XuMenglin XuQingnian XuZehua XuZhihao XuDi YangYouhua YangZhenwei YangZishuo YangYuezhe YaoLauren Emma YeomansHang YinJiesheng YuXuhao YuanOleg YushchenkoEttore ZaffaroniKristian Alexander ZarebskiMikhail ZavertyaevMilosz ZdybalOleksandr ZenaievMing ZengDongliang ZhangLiming ZhangShunan ZhangYanxi ZhangYu ZhangAlexey ZhelezovYangheng ZhengXiaokang ZhouYixiong ZhouXianglei ZhuValery ZhukovJennifer Brigitta ZonneveldStefano ZucchelliDavide ZulianiGianluca Zunica
• Organismes : Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire Leprince-Ringuet Laboratoire Leprince-Ringuet Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire d'Annecy de Physique des Particules Laboratoire Leprince-Ringuet Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Centre de Physique des Particules de Marseille Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Centre de Physique des Particules de Marseille Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire Leprince-Ringuet Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire d'Annecy de Physique des Particules Centre de Physique des Particules de Marseille Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique de Clermont Laboratoire de Physique des 2 Infinis Irène Joliot-Curie Laboratoire de Physique de Clermont Laboratoire de Physique de Clermont Laboratoire d'Annecy de Physique des Particules Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique Nucléaire et de Hautes Énergies Centre de Physique des Particules de Marseille Laboratoire de Physique Nucléaire et de Hautes Énergies Laboratoire de Physique des 2 Infinis Irène Joliot-Curie
• Publié dans Physical Review D le 02/11/2020

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Résumé : A search for time-dependent violation of the charge-parity symmetry in $D^0\to K^{+}{K}^{-}$ and $D^0\to {\pi }^{+}{\pi }^{-}$ decays is performed at the LHCb experiment using proton-proton collision data recorded from 2015 to 2018 at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of $6{\mathrm{fb}}^{-1}$. The $D^0$ meson is required to originate from a $D^{*}(2010{)}^{+}\to D^0{\pi }^{+}$ decay, such that its flavor at production is identified by the charge of the accompanying pion. The slope of the time-dependent asymmetry of the decay rates of $D^0$ and ${\overline{D}}^0$ mesons into the final states under consideration is measured to be $\mathrm{\Delta }{Y}_{K^{+}{K}^{-}}=(-2.3\pm 1.5\pm 0.3)\times {10}^{-4}$, $\mathrm{\Delta }{Y}_{{\pi }^{+}{\pi }^{-}}=(-4.0\pm 2.8\pm 0.4)\times {10}^{-4}$, where the first uncertainties are statistical and the second are systematic. These results are compatible with the conservation of the charge-parity symmetry at the level of 2 standard deviations and improve the precision by nearly a factor of 2.

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Marie-Pierre DubéMarc-André LegaultAudrey LemaçonLouis-Philippe Lemieux PerreaultRené FouodjioStefano VerganiSimon KouzFausto PintoAldo MaggioniRafael DiazColin BerryWolfgang KoenigJose Lopez-SendonHabib GamraGhassan KiwanGéraldine AsselinSylvie ProvostAmina BarhdadiMaxine SunMariève CossetteLucie BlondeauIan MongrainAnick DuboisDavid RhaindsNadia BouabdallaouiMichelle SamuelSimon de DenusPhilippe L'AllierMarie-Claude GuertinFrançois RoubilleJean-Claude Tardif
• Organismes : Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] Centre Hospitalier Régional Universitaire [Montpellier]
• Publié dans Circulation: Genomic and Precision Medicine le 27/05/2019

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Résumé : This article is published in its accepted form; it has not been copyedited and has not appeared in an issue of the journal. Preparation for inclusion in an issue of Circulation: Genomic and Precision Medicine involves copyediting, typesetting, proofreading, and author review, which may lead to differences between this accepted version of the manuscript and the final published version.

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Fichiers liés : 2021 Dube et al., Circ Genom.pdf

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• Type de publi. : Article dans une revue
• Date de publi. : 01/01/2021
• Auteurs : Houssein NasrallahYuanyuan MinEmmanuel LerayerTuan-Anh NguyenDidier PoinsotJulien RogerStéphane BrandèsOlivier HeintzPierre RoblinFranck JoliboisRomuald PoteauYannick CoppelMyrtil L KahnI.C. GerberM. Rosa AxetP. SerpJean-Cyrille Hierso
• Organismes : Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] Laboratoire de chimie de coordination Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon] Laboratoire Interdisciplinaire Carnot de Bourgogne Laboratoire de Génie Chimique Laboratoire de physique et chimie des nano-objets Laboratoire de physique et chimie des nano-objets Laboratoire de chimie de coordination Laboratoire de chimie de coordination Laboratoire de physique et chimie des nano-objets Laboratoire de chimie de coordination Laboratoire de chimie de coordination Institut de Chimie Moléculaire de l'Université de Bourgogne [Dijon]
• Publié dans JACS Au le 03/02/2021

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Résumé : Ultrasmall gold nanoparticles (NPs) stabilized in networks by polymantane ligands (diamondoids) were successfully used as precatalysts for highly selective heterogeneous gold-catalyzed dimethyl allyl(propargyl)malonate cyclization to 5-membered conjugated diene. Such reaction usually suffers from selectivity issues with homogeneous catalysts. This control over selectivity further opened the way to one-pot cascade reaction, as illustrated by the 1,6-enyne cycloisomerization–Diels–Alder reaction of dimethyl allyl propargyl malonate with maleic anhydride. The ability to assemble nanoparticles with controllable sizes and shapes within networks concerns research in sensors, medical diagnostics, information storage, and catalysis applications. Herein, the control of the synthesis of sub-2-nm gold NPs is achieved by the formation of dense networks, which are assembled in a single step reaction by employing ditopic polymantanethiols. By using 1,1′-bisadamantane-3,3′-dithiol (BAd-SH) and diamantane-4,9-dithiol (DAd-SH), serving both as bulky surface stabilizers and short-sized linkers, we provide a simple method to form uniformly small gold NPs (1.3 ± 0.2 nm to 1.6 ± 0.3 nm) embedded in rigid frameworks. These NP arrays are organized alongside short interparticular distances ranging from 1.9 to 2.7 nm. The analysis of gold NP surfaces and their modification were achieved in joint experimental and theoretical studies, using notably XPS, NMR, and DFT modeling. Our experimental studies and DFT analyses highlighted the necessary oxidative surface reorganization of individual nanoparticles for an effective enyne cycloisomerization. The modifications at bulky stabilizing ligands allow surface steric decongestion for the alkyne moiety activation but also result in network alteration by overoxidation of sulfurs. Thus, sub-2-nm nanoparticles originating from networks building create convenient conditions for generating reactive Au(I) surface single-sites—in the absence of silver additives—useful for heterogeneous gold-catalyzed enyne cyclization. These nanocatalysts, which as such ease organic products separation, also provide a convenient access for building further polycyclic complexity, owing to their high reactivity and selectivity.

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Fichiers liés : jacsau.0c00062.pdf

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