Philippe JEAN-PIERRE

---

• Type de publi. :
• Date de publi. : 22/09/2025
• Auteurs : Jean-Philippe SarretteValentin FerrerAndré RicardJ P GardouF. Marchal
• Organismes : Plasmas Réactifs Hors Equilibre Plasmas Réactifs Hors Equilibre Plasmas Réactifs Hors Equilibre Plasmas Réactifs Hors Equilibre LAboratoire PLasma et Conversion d'Energie

---

Résumé :

---

Fichiers liés : poster PLATHINIUM 2025.pdf

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 17/09/2025
• Auteurs : Bertrand ArnulfJerome LambertLionel KarlinCyrille TouzeauOlivier DecauxAurore PerrotSalomon ManierMohamad MohtyKarim BelhadjXavier LeleuCyrille HulinLydia MontesThomas ChalopinJill CorreTitouan CazaubielBenoit FermentAlexis TalbotJean-Marc SchianoStéphanie HarelPierre BoriesThierry FaconPhilippe Moreau
• Organismes : Hopital Saint-Louis [AP-HP] Epidemiology and Clinical Statistics for Tumor, Respiratory, and Resuscitation | Epidémiologie Clinique, STatistique, pour la Recherche en Santé Service de biostatistique et information médicale de l’hôpital Saint Louis (Equipe ECSTRA) Centre Hospitalier Lyon Sud [CHU - HCL] Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes-Angers Centre Hospitalier Universitaire de Rennes [CHU Rennes] = Rennes University Hospital [Pontchaillou] Pôle IUCT [CHU Toulouse] Centre de Recherches en Cancérologie de Toulouse Université de Lille Hétérogénéité, Plasticité et Résistance aux Thérapies des Cancers = Cancer Heterogeneity, Plasticity and Resistance to Therapies - UMR 9020 - U 1277 Centre Hospitalier Régional Universitaire [CHU Lille] CHU Saint-Antoine [AP-HP] Hôpital Henri Mondor Centre hospitalier universitaire de Poitiers = Poitiers University Hospital CIC de Poitiers – Centre d'investigation clinique de Poitiers (CIC 1402) Hôpital Haut-Lévêque [CHU Bordeaux] CHU Amiens-Picardie Laboratoire Charles Fabry / Gaz Quantiques Pôle IUCT [CHU Toulouse] Centre de Recherches en Cancérologie de Toulouse CHU de Bordeaux Pellegrin [Bordeaux] Hopital Saint-Louis [AP-HP] Université Paris Cité Institut Paoli-Calmettes Hopital Saint-Louis [AP-HP] Oncopole Claudius Regaud Centre Hospitalier Régional Universitaire [CHU Lille] Centre de Recherche en Cancérologie et Immunologie Intégrée Nantes-Angers

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 17/09/2025
• Auteurs : A EgalDenis VidaFrançois ColasBrigitte ZandaSylvain BouleyAsma SteinhausserPierre VernazzaL. FerrièreJ. GattaccecaM. BirlanJérémie VaubaillonKarl AntierSimon AnghelJ. DesmarsKevin BaillieL. MaquetSébastien BouquillonAdrien MalgoyreSimon JeanneJosep M Trigo-RodríguezEnrique HerreroJim RoweAndrew R. D. SmedleyAshley KingSalma SyllaDaniele GardiolDario BarghiniHervé LamyEmmanuël JehinDetlef KoschnyBjorn PoppeAndres JordánRene MendezKatherine VieiraHebe CremadesHasnaa Chennaoui AoudjehaneZouhair BenkhaldounJiří BorovičkaPavel SpurnýHadrien A. R. DevillepoixMarco MicheliDavide FarnocchiaShantanu NaiduPeter BrownPaul WiegertKrisztián SárneczkyAndrás PálNicholas A MoskovitzT. KaretaToni Santana-RosAlexis Le PichonGilles Mazet-RouxJulien VergozLuke McfaddenJelle D AssinkLäslo G EversDaniela KrietschHenner BusemannColin MadenLisa Maria EckartJean-Alix BarratPavel PovinecIvan SýkoraIvan Kontul’Oscar MarchhartMartin MartschiniSilke MerchelAlexander WieserMatthieu GounelleSylvain PontPierre Sans-JofreSebastiaan de VetIoannis BaziotisM. BrožMichaël MarssetJerôme VergneJosef HanušMaxime DevogèleLuca ConversiFrancisco OcañaLuca BuzziD. NedelcuAdrian SonkaFlorent LossePhilippe DupouyKorado KorlevićDieter HusarJost JahnDamir ŠegonMark McintyreRalf NeubertPierre BeckPatrick ShoberAnthony LagainOlivier HernandezDarrel RobertsonPeter Jenniskens
• Organismes : Géosciences Paris Saclay Laboratoire d'Astrophysique de Marseille Centre Européen de Recherche et d'Enseignement des Géosciences de l'Environnement Laboratoire Temps Espace Planetology and environments from ground astrometry and space exploration Laboratoire des Sciences de l'Environnement Marin (LEMAR)
• Publié dans Nature Astronomy le 15/02/2017

---

Résumé : Mitigation of the threat from airbursting asteroids requires an understanding of the potential risk they pose for the ground. How asteroids release their kinetic energy in the atmosphere is not well understood due to the rarity of large impacts. Here we present a comprehensive, space-to-laboratory characterization of an impact of an L chondrite, which represents a common type of Earth-impacting asteroid. Small asteroid 2023 CX1 was detected in space and predicted to impact over Normandy, France, on 13 February 2023. Observations from several independent sensors and reduction techniques revealed an unusual but potentially high-risk fragmentation behaviour. The nearly spherical 650 +/- 160 kg (72 +/- 6 cm diameter) asteroid catastrophically fragmented at a dynamic pressure of 4 MPa around 28 km altitude, releasing 98% of its total energy in a concentrated region of the atmosphere. The resulting shock wave was spherical, not cylindrical, and released more energy closer to the ground. This type of fragmentation increases the risk of substantial damage at ground level. These results warrant consideration for a planetary defence strategy for cases where a >3-4 MPa dynamic pressure is expected, including planning for evacuation of areas beneath anticipated disruption locations.

---

Fichiers liés : s41550-025-02659-8.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 12/09/2025
• Auteurs : Jean-Charles PicaudOlivier ClarisMercedes Gil-CamposIgnacio Salamanca de la CuevaLuc CornettePhilippe AllietAndré LekeMireille CastanetHugues PiloquetVirginie de HalleuxDelphine MitanchezYvan VandenplasPierre MatonFrank JochumDirk OlbertzSergio Negre PolicarpoLuca LavalleCecilia FumeroPaula Rodriguez-GarciaJanne Marie MollIrma Silva-ZolezziBoutaina ZemraniNicholas HaysNorbert SprengerJavier Miranda-Mallea
• Organismes : Hôpital de la Croix-Rousse [CHU - HCL] Cardiovasculaire, métabolisme, diabétologie et nutrition Hospices Civils de Lyon Université Claude Bernard Lyon 1 Instituto Maimonides de Investigación Biomédica de Cordoba Instituto Hispalense de Pediatria [Sevilla, Spain] Sint-Jan General Hospital Jessa Ziekenhuis = Jessa Hospital Périnatalité et Risques Toxiques - UMR INERIS_I 1 UPJV Neuroendocrine, Endocrine and Germinal Differentiation Communication Centre Hospitalier Universitaire de Nantes = Nantes University Hospital Physiopathologie des Adaptations Nutritionnelles Centre Hospitalier Universitaire de Liège Centre Hospitalier Régional Universitaire de Tours Vrije Universiteit Brussel [Bruxelles] Clinique CHC MontLégia [Liège, Belgium] Evangelisches Waldkrankenhaus Spandau University Medical Center Rostock Hospital Quirónsalud Bizkaia [Bilbao] Nestlé Research Center | Centre de recherche Nestlé [Lausanne] Nestlé Research Center | Centre de recherche Nestlé [Lausanne] Copenhagen University Hospitals [Copenhague] Copenhagen University Hospitals [Copenhague] Nestlé Product Technology Center Dairy Nestlé Product Technology Center Dairy Nestlé Product Technology Center Dairy Nestlé Institute of Health Sciences SA [Lausanne, Switzerland] Hospital Vithas Vitoria = Vithas Vitoria Hospital
• Publié dans Frontiers in Nutrition le 25/10/2020

---

Fichiers liés : 2025_Picaud_Front_Nutrition.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 10/09/2025
• Auteurs : Zhaojie ChaiGuansheng LiPapa Alioune NdourPhilippe ConnesPierre BuffetMélanie FrancoGeorge Em Karniadakis
• Organismes : Brown University Brown University Biologie Intégrée du Globule Rouge Laboratoire Interuniversitaire de Biologie de la Motricité Biologie Intégrée du Globule Rouge Biologie Intégrée du Globule Rouge Brown University
• Publié dans PLoS Computational Biology le 27/10/2020

---

Résumé : Gaucher Disease (GD) is a rare genetic disorder characterized by a deficiency in the enzyme glucocerebrosidase, leading to the accumulation of glucosylceramide in various cells, including red blood cells (RBCs). This accumulation results in altered biomechanical properties and rheological behavior of RBCs, which may play an important role in blood rheology and the development of bone infarcts, avascular necrosis (AVN) and other bone diseases associated with GD. In this study, dissipative particle dynamics (DPD) simulations are employed to investigate the biomechanics and rheology of blood and RBCs in GD under various flow conditions. The model incorporates the unique characteristics of GD RBCs, such as decreased deformability and increased aggregation properties, and aims to capture the resulting changes in RBC biophysics and blood viscosity. This study is the first to explore the Young's modulus and aggregation parameters of GD RBCs by validating simulations with confocal imaging and experimental RBC disaggregation thresholds. Through in silico simulations, we examine the impact of hematocrit, RBC disaggregation threshold, and cell stiffness on blood viscosity in GD. The results reveal three distinct domains of GD blood viscosity based on shear rate: the aggregation domain, where the RBC disaggregation threshold predominantly influences blood viscosity; the transition area, where both RBC aggregation and stiffness impact on blood viscosity; and the stiffness domain, where the stiffness of RBCs emerges as the primary determinant of blood viscosity. By analyzing RBC mechanical properties and blood viscosity in relation to bone disease, we find that the RBC aggregation properties, deformability, and blood viscosity, may contribute to its onset. These findings enhance our understanding of how changes in RBC properties impact on blood viscosity and may affect bone health, offering a partial explanation for the bone complications observed in GD patients.

---

Fichiers liés : journal.pcbi.1012705.pdf

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 09/09/2025
• Auteurs : Sofia Avalos-AlaisMaciej JedynakAnthony BoyerBlandine Chanteloup-ForêtCristiana PinheiroChristopher ClineSara ParmigianiYasser Alemán-GómezPatric HagmannCorey KellerOlivier DavidClaude AdamVincent NavarroArnaud BirabenAnca NicaDominique MenardMilan BrazdilRobert KubaJitka KočvarováMartin PailIrena DoležalováFrançois DubeauJean GotmanPhilippe RyvlinJean IsnardHélène CatenoixAlexandra MontavontSylvain RheimsFabrice BartolomeiAgnès TrébuchonAileen McgonigalWenjing ZhouHaixiang WangSinclair LiuZhang WeiZhu DanGuo QiangHu XiangshuLi HuaHua GangWang WenshengMei XiFeng YigangRima NabboutMarie BourgeoisAnna KamińskaThomas BlauwblommeMercedes GarcésAntonio ValentinRinki SinghLiisa MetsähonkalaEija GailyLeena LauronenMaria PeltolaFrancine ChassouxElizabeth LandréPhilippe DerambureWilliam SzurhajMaxime ChochoisEdouard HirschMaria Paola ValentiJulia SchollyLuc ValtonMarie DenuelleJonathan CurotRodrigo RocamoraAlessandro PrincipeMiguel LeyIoana MindrutaAndrei BarboricaStefano FrancioneRoberto MaiLino NobiliIvana SartoriLaura TassiLouis MaillardJean-Pierre VignalJacques JonasLouise TyvaertMathilde ChipauxDelphine TaussigPhilippe KahaneLorella MinottiAnne-Sophie JobVéronique MichelMarie de MontaudoinJérôme AupyViviane BouilleretAna Maria PetrescuPascal MasnouClaire DussauleMarion QuirinsDelphine TaussigCarmen BarbaRenzo GuerriniMatteo LengeElisa Nacci
• Organismes : Institut de Neurosciences des Systèmes Institut de Neurosciences des Systèmes Institut de Neurosciences des Systèmes [GIN] Grenoble Institut des Neurosciences IFR de neurosciences de Strasbourg Stanford University Stanford University Université de Lausanne = University of Lausanne Université de Lausanne = University of Lausanne Stanford University Institut de Neurosciences des Systèmes Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center Department of Functional Neurology and Epileptology, Hospices Civils de Lyon and University of Lyon, Lyon, France
• Publié dans Brain - A Journal of Neurology le 29/10/2020

---

Résumé : Abstract The lateral prefrontal cortex (LPFC) serves as a critical hub for higher-order cognitive and executive functions in the human brain, coordinating brain networks whose disruption has been implicated in many neurological and psychiatric disorders. While transcranial brain stimulation treatments often target the LPFC, our current understanding of connectivity profiles guiding these interventions based on electrophysiology remains limited. Here, we present a high-resolution probabilistic map of bidirectional effective connectivity between the LPFC and widespread cortical and subcortical regions. This map is derived from intracranial evoked potential analysis of 48,797 intracranial direct electrical stimulation runs across 759 implantations in 724 patients with refractory epilepsy (368 male, 354 female, two unspecified; mean age 24±13.5 years). We mapped probabilistic connectivity between brain parcels with adaptive resolution – higher resolution in the LPFC in the hemisphere of interest and lower elsewhere – maintaining statistical power while achieving 95% average confidence interval of ∼0.03 for connectivity probability estimates. In addition, the significance threshold (p-value) for probabilistic connectivity was obtained from surrogate distributions. Overall, we observed remarkable symmetry between afferent and efferent connectivity patterns of the LPFC, with a slight preference for efferent connections (mean slope = 0.92±0.09, mean R² = 0.93±0.025). For example, connections between the inferior frontal gyrus (IFG) and anterior cingulate showed notable directional asymmetry. The IFG strongly projected to most brain networks compared to other LPFC regions, with the strongest connectivity to the ventral attention network (0.26±0.01 compared to values between 0.15 and 0.21 in other LPFC regions). Posterior DLPFC demonstrated stronger connectivity to brain networks compared to anterior DLPFC regions (eg. 0.21±0.01 vs 0.15±0.01 for connectivity to ventral attention network), with the exception of the limbic cortex. All LPFC subregions strongly projected to the fronto-parietal (greater than 0.17) and ventral attention (greater than 0.15) networks, with moderate connections to the default network (between 0.1 and 0.15, with the maximum corresponding to superior DLPFC). Finally, latency analysis suggested that the left LPFC's influence on ipsilateral emotion-related regions is primarily polysynaptic, with particularly strong pathways from IFG to amygdala (0.16±0.02) and hippocampus (0.12±0.01). Taken together, these comprehensive connectivity maps provide a new detailed electrophysiological foundation for understanding the functional anatomy of LPFC and guiding targeted brain stimulation protocols.

---

Source

---

• Type de publi. : Article dans une revue
• Date de publi. : 09/09/2025
• Auteurs : Caroline BraudP KeravecIngrid NeunaberSandrine AubrunJean-Luc AttiéPierre DurandPhilippe RicaudJean-François GeorgisEmmanuel LeclercLise MourreClaire Taymans
• Organismes : Laboratoire de science et génie des surfaces Centre d'études spatiales de la biosphère Laboratoire de recherche en Hydrodynamique, Énergétique et Environnement Atmosphérique Laboratoire de recherche en Hydrodynamique, Énergétique et Environnement Atmosphérique Centre national de recherches météorologiques
• Publié dans Wind Energy Science le 13/05/2020

---

Résumé : Abstract. A comprehensive meteorological data set from an operational wind farm, consisting of six 2 MW turbines, has been made available. A meteorological mast, equipped with sonic anemometers at four different heights, was installed at the center of the farm and has collected data over 3 years. The data set is further supplemented with radiometer measurements for atmospheric stability analysis. Simultaneously, supervisory control and data acquisition (SCADA) data were acquired to provide operational information about the wind turbines, including inter alia power production and wind direction. Additionally, the turbine blades were scanned to support aerodynamic simulations. This unique and comprehensive database has been made accessible to the research community through the AERIS platform.

---

Fichiers liés : wes-10-1929-2025.pdf

---

Source

---

• Type de publi. :
• Date de publi. : 08/09/2025
• Auteurs : Emma AraignousPierre BourdaudKarine R HeerahJuliette delavenneLydie CouturierYann PlanqueA AcouE AlmoricHugues BlanchetFrida Ben Rais LasramN BuissonAntoine ChabrolleDominique ClorennecMagali CollinL DespringhereR FabletC FerryF GallienLisa GarnierL IborraFrançois Le Loc’hNathalie NiquilG NolibéJean-Philippe PezyEmma QuintardF SamaranT TrancartN UrienJehanne Prevot
• Organismes : Patrimoine naturel Laboratoire d’Océanologie et de Géosciences (LOG) - UMR 8187 Laboratoire des Sciences de l'Environnement Marin (LEMAR) Morphodynamique Continentale et Côtière Normandie Université Centre National de la Recherche Scientifique Université de Caen Normandie Morphodynamique Continentale et Côtière

---

Source

---

• Type de publi. :
• Date de publi. : 08/09/2025
• Auteurs : Laurie MichaudAurore RaouxJean-Philippe PezyEmma AraignousPierre BourdaudNathalie Niquil
• Organismes : Morphodynamique Continentale et Côtière Morphodynamique Continentale et Côtière Morphodynamique Continentale et Côtière France Énergies Marines [Brest] France Énergies Marines [Brest] Morphodynamique Continentale et Côtière Normandie Université Centre National de la Recherche Scientifique Université de Caen Normandie

---

Source

---

• Type de publi. : Communication dans un congrès
• Date de publi. : 08/09/2025
• Auteurs : Clément MathieuJérôme WassermannSébastien PéraltaRonan L. HébertPierre M. AdlerJean-Louis GalliasPhilippe Bromblet
• Organismes : Laboratoire de mécanique et matériaux du génie civil Laboratoire de mécanique et matériaux du génie civil Laboratoire de Physico-chimie des Polymères et des Interfaces ISTeP-CY Milieux Environnementaux, Transferts et Interactions dans les hydrosystèmes et les Sols Laboratoire de mécanique et matériaux du génie civil Centre Interdisciplinaire de Conservation et Restauration du Patrimoine

---

Résumé : Salt crystallization within the heritage stones is recognized as a major cause of damage. In particular, sodium sulfates which are very commonly encountered in natural environment, are recognized as the most destructive salts. The mechanisms leading to the stone damage are still not well defined. The identification of the salt crystallization sequence and of the spatial distribution at the pore scale, remain a real scientific challenge. The sodium sulfate crystallization within true natural porous network is studied at pore scales during weathering cycles. Savonnières limestone samples are exposed to salt by successive imbibition and evaporation of a 1 mol/L sodium sulfate solution at constant ambient temperature and relative humidity conditions. Phases characterization and topography cartographies are performed using Raman spectroscopy and Atomic Force Microscopy respectively. The two combined technics on a same limestone sample help to characterize the spatial distribution of neocrystallized salt phases within the porous network. The results shown that the micro and the macropores of the limestones are mainly filled by thenardite phase V microcrystals. Large crystals of mirabilite could be formed in the stone before the dehydration. Gypsum crystals have been observed too and are located in the micropores of the limestone: at interfacial zones between oolites and sparitic cement and also in the micropores of the oolites. The presence of gypsum could indicate a chemical reaction between the sodium sulfate solution and the limestone.

---

Source